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Full-Text Articles in Entire DC Network
Answers To Common Misconceptions About Biological Evolution, Leah M. Abebe, Blake Bartels, Kaitlyn M. Caron, Adam M. Gleeson, Samuel N. Johnson, Tyler J. Kluza, Nicholas W. Knopik, Kristen N. Kramer, Masiel S. Maza, Kaitlyn A. Stava, Kaitlyn Sullivan, Jordan T. Trimble, Robert M. Zink
Answers To Common Misconceptions About Biological Evolution, Leah M. Abebe, Blake Bartels, Kaitlyn M. Caron, Adam M. Gleeson, Samuel N. Johnson, Tyler J. Kluza, Nicholas W. Knopik, Kristen N. Kramer, Masiel S. Maza, Kaitlyn A. Stava, Kaitlyn Sullivan, Jordan T. Trimble, Robert M. Zink
Papers in Evolution
“When you have an established scientific emergent truth, it is true whether or not you believe in it.” Neil deGrasse Tyson, Science in America. Very few people outside of a particular scientific discipline can actually say they understand it, because most do not have the training to “speak the language.” They are then not particularly bothered by its tenets and predictions. Of all the major branches of science, however, evolutionary biology is an exception to this generalization because even though people are not versed in the field, they sometimes have a negative, knee-jerk objection. This objection is often because they …
Hexapod Herald - Vol. 29, No. 3, May 2017
Hexapod Herald - Vol. 29, No. 3, May 2017
Hexapod Herald and Other Entomology Department Newsletters
Contents: Congratulations - Retirement Reception for Dr. Shripat Kamble - Welcome - Faculty News - Publications - Grants - Student News - Kansas Entomological Society Annual Meeting, April 15, 2017 - Blast from the Past - Travel
Nebline, May 2017
NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County
Feature: Biosolids Land Application Program Celebrating 25 Years of Benefiting the Community
Food & Health
Farm & Acreage
Pests & Wildlife
Horticulture
Early Childhood
4-H & Youth
and other extension news and events
"Choir Is For Girls": Intersectional Mixed Methods Perspectives On Adolescent Gender Identity, Singing Interest, And Choral Music Participation, Briana E. Nannen
"Choir Is For Girls": Intersectional Mixed Methods Perspectives On Adolescent Gender Identity, Singing Interest, And Choral Music Participation, Briana E. Nannen
Glenn Korff School of Music: Dissertations, Theses, Student Creative Work, and Performances
As students progress through adolescent development, researchers have observed a lack of male participation in choral music activities. This male to female imbalance is often attributed to a perception that singing is a feminine activity and results in a lack of balance in choral music ensembles. The purpose of this mixed methods study was to explore adolescent gender identity as it relates to singing interest and choral music participation. An explanatory sequential mixed methods design was used, in which quantitative data were collected and analyzed followed by in-depth qualitative interviews. A group of 9th grade students (n=174) completed the …
Development Of Peritoneal Microbubble Oxygenation As An Extrapulmonary Treatment For Hypoxia, Nathan Legband
Development Of Peritoneal Microbubble Oxygenation As An Extrapulmonary Treatment For Hypoxia, Nathan Legband
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Patients affected by a respiratory disease or injury experience a substantially impaired respiratory system and as a consequence are unable to obtain a sufficient amount of oxygen. Hypoxia can quickly result in developing permanent tissue damage or death. Currently, the medical methods of treating hypoxia are mechanical ventilation or extracorporeal membrane oxygenation. However, these treatments are ineffective in certain cases and possess significant additional risks including barotrauma, infection, hemorrhage, and thrombosis.
The extrapulmonary method of peritoneal oxygenation has been investigated by other research groups as a potential alternative to providing supplemental oxygen in hypoxic animals. In peritoneal oxygenation, the peritoneum, …
On The Wetting States Of Low Melting Point Metal Galinstan And Wetting Characteristics Of 3-Dimensional Nanostructured Fractal Surfaces, Ethan Allan Davis
On The Wetting States Of Low Melting Point Metal Galinstan And Wetting Characteristics Of 3-Dimensional Nanostructured Fractal Surfaces, Ethan Allan Davis
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Exergy, or the availability of energy for useful work, is a critical issue that must be addressed to accommodate growing energy demands of society. Increasing population and steady advancement of technology necessitates novel approaches to the management, conversion, and storage of energy. Per the Lawrence Livermore National Laboratory, approximately 60 percent of the energy used by the United States in 2015 was rejected as waste [1]; a large quantity of which can be assumed to be in the form of heat. Therefore, novel thermal management methods for waste heat are critical to increasing energy efficiency and sustainability in the future. …
Design And Validation Of An In Vivo Long-Term Attachment Capsule Robot, Wanchuan Xie
Design And Validation Of An In Vivo Long-Term Attachment Capsule Robot, Wanchuan Xie
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
The invention of capsule endoscopy (CE) made the non-invasive monitoring of the entire small bowel possible and became the primary means for diagnosing small bowel pathology. In the last decade, capsule robots have been transformed from diagnostic devices into a widely studied biomedical platform with the potential for active locomotion, drug delivery and therapeutic capabilities. To perform accurate on-site drug release and therapy, it is necessary for a capsule robot to be able to attach to the intestinal tissue and maintain its position long-term. Design challenges derive from the task of long-term mucosal adhesion which requires firm, quick-response attachment without …
Land Use As An Indicator Of Stream Habitat Quality In Salt Creek, Adam Brown
Land Use As An Indicator Of Stream Habitat Quality In Salt Creek, Adam Brown
Department of Environmental Studies: Undergraduate Student Theses
This study sought to quantify land use types in Lancaster County and identify which, if any, environmental parameters were significantly influencing fish and invertebrate distribution in the Salt Creek basin. Historical sampling data were obtained from the Nebraska Department of Environmental Quality. Watershed land cover maps were created and the percentages of urban/developed, forested, row crop, and grassland use were calculated. This data was combined with NDEQ water quality parameter, fish, and invertebrate sampling data to conduct nonmetric multidimensional scaling. This analysis did not provide significant conclusions about the driving force of fish and invertebrate distribution in this region because …
Patch Seeding On An Extensive Green Roof: Initial Experiment On Microclimate Impacts, Zhuqing Xu
Patch Seeding On An Extensive Green Roof: Initial Experiment On Microclimate Impacts, Zhuqing Xu
Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research
The green roof provides not only aesthetic values but also many ecological benefits. In North America, seeding or reseeding with native species becomes increasingly popular as a result of its high efficacy and low cost. The extreme temperature and a lack of water on the green roof impose restrictions on seeds germination that determines the success of a seeding program.
The study started on June 1 and was completed by July 15. Five Great Plains native species were hand-seeded in two blocks on Larson Building green roof, along with two blocks set up in the greenhouse at University of Nebraska-Lincoln …
Response Of Problematic Weed Populations In Nebraska To Glyphosate, Spencer L. Samuelson
Response Of Problematic Weed Populations In Nebraska To Glyphosate, Spencer L. Samuelson
Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research
There are currently nine reported herbicide-resistant weed species in Nebraska, six of which are resistant to glyphosate. Overall distribution and frequency of these resistant species is unknown.
The objectives of this research were to understand the frequency and distribution of glyphosate-resistant weeds in Nebraska. Common and problematic weeds of Nebraska were arbitrarily collected from fields in 77 counties during the fall of 2013-2015. From our statewide collection, five species including: horseweed (Conyza canadensis (L.) Cronq.), kochia (Kochia scoparia (L.) Schrad.), Russian-thistle (Salsola tragus L.), giant ragweed (Ambrosia trifida L.), and common lambsquarters (Chenopodium album L.) …
Examining Admission Policy Change At A Private, Tuition-Dependent, Baccalaureate Institution In An Urban Setting: A Qualitative Case Study, Christopher B. Gage
Examining Admission Policy Change At A Private, Tuition-Dependent, Baccalaureate Institution In An Urban Setting: A Qualitative Case Study, Christopher B. Gage
College of Education and Human Sciences: Dissertations, Theses, and Student Research
Higher education in America is resilient; in the face of seemingly insurmountable challenges, higher education manages to weather the storm of change, pressure, doubt, and criticism. Consider the following challenges: shifting demographics, escalating tuition, decreased state funding, retention and graduation rates, flat tuition revenue, competition for students, student preparedness, and student loan debt. Enrollment managers navigate these formidable impediments through innovative policy change, leadership and faithfulness to institutional mission (Eckel & Kezar, 2003b; Hector, 2016). Test-optional admission policies are changing the landscape of the enrollment management profession. Critics say some institutions adopt test-optional admissions to improve their national rankings by …
An Exploratory Mixed-Methods Examination Of Empathy And Multiple Intelligences Among Youth Involved In Bullying, Heather Schwartz
An Exploratory Mixed-Methods Examination Of Empathy And Multiple Intelligences Among Youth Involved In Bullying, Heather Schwartz
College of Education and Human Sciences: Dissertations, Theses, and Student Research
Bullying is a significant issue among school-aged youth, and it is important to examine the underlying mechanisms of these behaviors. Studies have shown that one characteristic found among some children who bully is a lack of empathy. Previous literature examining empathy and bullying has typically relied on the use of self-report data. Few studies have included other ways of evaluating empathy. Self-report data can be limiting, particularly for individuals who possess strengths other than verbal/linguistic. Drawings have been found to reveal insight into children’s emotions and may be more suited to assessing empathy. Studying children’s drawings of bullying, and their …
Thinking About Race: How Group Biases Interact With Ideological Principles To Yield Attitudes Toward Government Assistance, Frank John Gonzalez
Thinking About Race: How Group Biases Interact With Ideological Principles To Yield Attitudes Toward Government Assistance, Frank John Gonzalez
Department of Political Science: Dissertations, Theses, and Student Research
When are people more likely to evaluate race-targeted government assistance based on ideological principles rather than racial prejudice? In order to answer this question, it is necessary to understand the mechanisms by which prejudice influences political attitudes. In this dissertation, I develop a theoretical model for explaining how deep-seated, automatic group biases interact with higher-order, ideological principles in order to influence attitudes toward race-targeted government assistance. I suggest group-based principles are more important than individualistic values or ingroup favoritism in explaining race-targeted policy attitudes. I argue that when people evaluate race-targeted policies, controlled neural processes translate automatic neural processes into …
The Terror Of The Political: Community, Identity, And Apocalypse In Don Delillo's Falling Man, Dillon Rockrohr
The Terror Of The Political: Community, Identity, And Apocalypse In Don Delillo's Falling Man, Dillon Rockrohr
Department of English: Dissertations, Theses, and Student Research
Falling Man by Don DeLillo casts the event of 9/11 and its aftermath in such a way that the novel itself enacts an aesthetic terror aimed at explicating the ubiquitous social-atmospheric elements of community- and identity-formation out of which terror precipitates. As DeLillo figures terrorism in the novel as apocalyptic in that it is a violence that reveals the violence constitutive of political community, including the political community of liberal democracy, which ostensibly relegates violence to domains not considered legitimately political. DeLillo’s novel, as an act of aesthetic terrorism, not only thematizes the instantiation of terror that precipitates out of …
Ethics Of Care On The Narrative Margins Of Willa Cather’S The Professor’S House And Death Comes For The Archbishop, Jeannette E. Schollaert
Ethics Of Care On The Narrative Margins Of Willa Cather’S The Professor’S House And Death Comes For The Archbishop, Jeannette E. Schollaert
Department of English: Dissertations, Theses, and Student Research
Willa Cather’s Southwestern novels feature cultured male protagonists as the driving sources of action. The male characters explore the natural world and advance the plot, but Cather positions female figures, particularly spinster figures, on the sidelines of the protagonists’ plots to offer support and connection with the natural world. Using an ethic of care framework and ecofeminist Val Plumwood’s master model, this thesis examines the ways in which Cather marginalizes female figures even as they serve crucial roles in the male protagonists’ development. While the male protagonists link spinster figures and sexualized feminine bodies with the natural world, they imbue …
Heterogeneity Of Avian Breeding Habitat On Grazing Lands Of The Northern Great Plains, Maggi S. Sliwinski
Heterogeneity Of Avian Breeding Habitat On Grazing Lands Of The Northern Great Plains, Maggi S. Sliwinski
School of Natural Resources: Dissertations, Theses, and Student Research
Native rangelands in the Great Plains are largely privately owned and used for beef production. Vegetation heterogeneity is important for maintaining biodiversity, but private land may be more homogenous than desired. My research had two components: 1) to examine whether a variety of grazing strategies created vegetation heterogeneity in a large, intact rangeland, and 2) to understand beef producers’ attitudes about vegetation heterogeneity.
First, I sampled vegetation structure, composition, and bird abundance at multiple plots on eleven management units in Cherry County, Nebraska. Units were managed with commonly used grazing strategies (e.g., short-duration grazing and season-long continuous grazing). I examined …
Not Infertile, Can’T Have Children: Non-Reproductive Health Barriers To A Wanted Child, Jennifer A. Andersen
Not Infertile, Can’T Have Children: Non-Reproductive Health Barriers To A Wanted Child, Jennifer A. Andersen
Department of Sociology: Dissertations, Theses, and Student Research
Non-reproductive health barriers to a wanted baby are an understudied population in the field of infertility research. This is a concern for fertility, public health, and family scholars as the lack of information can have affects the attitudes, knowledge, and behaviors of couples with non-reproductive health barriers. Using the National Survey of Fertility Barriers (NSFB) and Survey Driven Narrative Construction, I was able to identify thirty-two women and their partners who have confronted a non-reproductive health barrier. These women did not self-identify and were grouped as such by the author. I found that the majority of the couples do not …
Genetically Encoded Fluorescent Protein Biosensor For Nitric Oxide, Wenjia Zhai
Genetically Encoded Fluorescent Protein Biosensor For Nitric Oxide, Wenjia Zhai
Department of Chemistry: Dissertations, Theses, and Student Research
Nitric oxide (NO) is an important molecule in living cells for signaling, thus a specific sensor to detect its level in live cells is needed. Currently there are a few small molecule probes for the detection of NO. A common shortcoming of these probes is their unavoidable leakage from the target cells. In this project, I seek to develop a novel green fluorescent protein (GFP)-based biosensor to detect cellular NO. This GFP-based sensor is genetically encodable and can potentially avoid the possible false positive result due to the leakage. I synthesized an unnatural amino acid (unAA) and examined its incorporation …
The Effect Of Spray Parameters On The Application Of Enlist Duo, Matthew R. Nelson
The Effect Of Spray Parameters On The Application Of Enlist Duo, Matthew R. Nelson
Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research
The emergence of new weed control challenges, along with shifts in weed management strategies and cultural practices, has resulted in an increased reliance on chemical weed control in United States (US) cropping systems. As a result, numerous weed species have evolved resistance to herbicides such as glyphosate, thus prompting the development of new weed control systems designed to aid growers in managing resistant weeds. While these new weed control options may give growers additional management options, the high sensitivity of broadleaf crops, fruits, and vegetables to products containing 2,4-D or dicamba increases the potential for herbicide drift resulting from application …
Atopic Dermatitis And Food Sensitization In South African Toddlers: Role Of Fiber And Gut Microbiota, Mahboobeh Mahdavinia, Heather Rasmussen, Phillip Engen, Jolice P. Van Den Berg, Erika Davis, Krista Engen, Stefan J. Green, Ankur Naqib, Maresa Botha, Claudia Gray, Nonhlanhla Lunjani, Carol Hlela, Wisdom Basera, Lelani Hobane, Alexandra Watkins, Mary C. Tobin, Alan Landay, Ali Keshavarzian, Michael E. Levin
Atopic Dermatitis And Food Sensitization In South African Toddlers: Role Of Fiber And Gut Microbiota, Mahboobeh Mahdavinia, Heather Rasmussen, Phillip Engen, Jolice P. Van Den Berg, Erika Davis, Krista Engen, Stefan J. Green, Ankur Naqib, Maresa Botha, Claudia Gray, Nonhlanhla Lunjani, Carol Hlela, Wisdom Basera, Lelani Hobane, Alexandra Watkins, Mary C. Tobin, Alan Landay, Ali Keshavarzian, Michael E. Levin
Department of Nutrition and Health Sciences: Faculty Publications
The pathogenesis of atopic dermatitis (AD) is complex and related to allergic responses and defects in skin barrier function. In common with many atopic diseases, the prevalence of AD has been increasing across the world.1 One of the theories for this increase is increased hygiene and urbanization-related changes in the environment, which can affect the human microbiome.2 Previous studies have found associations between the composition of the early gut microbiome and development of atopic conditions, including AD.3 Although the rate of atopic conditions, including AD and food allergy, is increasing on all continents, the prevalence of these diseases is still …
Behavioral Plasticity Across Non-Social Contexts In Female Green Swordtails, Xiphophorus Helleri, Lindsey M. Coit
Behavioral Plasticity Across Non-Social Contexts In Female Green Swordtails, Xiphophorus Helleri, Lindsey M. Coit
School of Biological Sciences: Dissertations, Theses, and Student Research
Phenotypic plasticity is the ability of an individual to alter its phenotype in response to environmental change. Individuals that express plasticity in behavior can quickly respond to changes that occur in the environment. Therefore, individuals that exhibit behavioral plasticity can alter their behavioral expression to best match current environmental conditions. The degree and direction of behavioral plasticity may be influenced by variation in individual characteristics. Understanding how variation in individual traits affects behavioral plasticity, and, whether patterns of behavioral plasticity are consistent across behavioral contexts are important topics to explore as we try to better understand how plasticity evolves and …
Variation In Density Dependent Seedling Survival Across Forests Of Different Successional Age And Hunting Protection Status, Nohemi Huanca-Nunez
Variation In Density Dependent Seedling Survival Across Forests Of Different Successional Age And Hunting Protection Status, Nohemi Huanca-Nunez
School of Biological Sciences: Dissertations, Theses, and Student Research
Over 50% of the original extent of tropical forests has been cleared. Restoration of secondary forests is important for maintaining the ecosystem services that mature tropical forests provide. Density dependence (DD) is thought to be a major mechanism for shaping forest community structure and may cause reduced spatial aggregation among individuals of the same species, allowing for maintenance of diversity. While much research has focused on DD in mature tropical forests, few studies have examined how DD may influence community structure in secondary forests, many of which are also exposed to hunting. There are several important agents of negative and …
Backgrounding Calf Management Strategies Using Corn Residue And Double Cropped Forages, Jordan L. Cox-O'Neill
Backgrounding Calf Management Strategies Using Corn Residue And Double Cropped Forages, Jordan L. Cox-O'Neill
Department of Animal Science: Dissertations, Theses, and Student Research
Approximately 70% of calves in the U.S. are born in the spring and weaned in the fall, this results in a large supply of calves potentially available for backgrounding over the winter. Backgrounding systems positively impact the beef industry by efficiently using forage resources available. These systems also provide production value by enhancing the calf’s frame size, mature BW (increase HCW), and health prior to entering the feedlot. In Nebraska opportunities to integrate both crop and livestock production, by backgrounding calves abound. Approximately 13,100 metric tons of corn residue or 34,000 Animal Unit Months are available for grazing in Nebraska. …
Use Of Byproducts In Forage-Based, Post-Weaning Beef Systems And Effects Of Serial Slaughter On Performance And Profitability, Robert Gregory Bondurant Jr.
Use Of Byproducts In Forage-Based, Post-Weaning Beef Systems And Effects Of Serial Slaughter On Performance And Profitability, Robert Gregory Bondurant Jr.
Department of Animal Science: Dissertations, Theses, and Student Research
Crude glycerin was included in high-forage beef growing diets at 0, 4, 8, and 12% diet DM to determine the effect on fiber digestion by evaluating changes in microbial species abundance, NDF digestibility, and VFA concentrations. Total tract NDF digestibility decreased with increasing inclusion of GLY in high-forage diets. However, there was no decrease in in situ NDF digestibility and Fibrobacter succinogenes microbial populations were unaffected, indicating that fiber digestion was not directly affected by inclusion of GLY. Acetate decreased while propionate and butyrate VFA proportions increased as GLY increased.
Spayed heifers were utilized in a 2-yr study to evaluate …
Effects Of Energy Restriction During Gilt Development On Milk Nutrient Profile, Progeny Biomarkers, And Growth Performance, Shana Marie Barnett
Effects Of Energy Restriction During Gilt Development On Milk Nutrient Profile, Progeny Biomarkers, And Growth Performance, Shana Marie Barnett
Department of Animal Science: Dissertations, Theses, and Student Research
Two experiments were conducted at separate times to evaluate the effects of sow dietary treatment on piglet growth performance. One experiment solely focused on the growth performance of parity 1 piglets from gilt batches 5 through 13. The other experiment focused on growth performance of piglets from batch 14, parity 1, as well as, analysis of growth biomarkers, GLP-2 and Insulin. Milk samples from sows of each dietary treatment were collected and analyzed for oligosaccharide composition, nutrient composition, and insulin levels.
The first experiment utilized 733 sows that were fed either a restricted (RESTR) of ad libitum (ADLIB) diet during …
Replicability And Reproducibility In Comparative Psychology, Jeffrey R. Stevens
Replicability And Reproducibility In Comparative Psychology, Jeffrey R. Stevens
Jeffrey Stevens Publications
Psychology faces a replication crisis. The Reproducibility Project: Psychology sought to replicate the effects of 100 psychology studies. Though 97% of the original studies produced statistically significant results, only 36% of the replication studies did so (Open Science Collaboration, 2015). This inability to replicate previously published results, however, is not limited to psychology (Ioannidis, 2005). Replication projects in medicine (Prinz et al., 2011) and behavioral economics (Camerer et al., 2016) resulted in replication rates of 25 and 61%, respectively, and analyses in genetics (Munafò, 2009) and neuroscience (Button et al., 2013) question the validity of studies in those fields. Science, …
Spring Field Report, March-May 2017, W. Ross Silcock
Spring Field Report, March-May 2017, W. Ross Silcock
Nebraska Bird Review
In general, this was a routine spring, except for remarkable numbers reported of several species, and a notable paucity of most species of wood-warblers. A huge Snow Goose flock in the east was estimated to contain 500,000- 1,000,000 birds; other notable numbers were 2000 Tree Swallows and 5000 Cliff Swallows, both record counts, 44 Black-capped Chickadees, 300 House Wrens, 62 Fox and 76 Song Sparrows on the same day at a single location, 168 Dark-eyed (Slate-colored) Juncos, and 10,000 Common Grackles. Perhaps the most notable phenomenon this spring was the dearth of migrant wood-warblers. Joel Jorgensen constructed graphics based on …
Species And Trichothecene Genotypes Of Fusarium Head Blight Pathogens In Nebraska, Usa In 2015–2016, Esteban Valverde-Bogantes
Species And Trichothecene Genotypes Of Fusarium Head Blight Pathogens In Nebraska, Usa In 2015–2016, Esteban Valverde-Bogantes
Department of Food Science and Technology: Dissertations, Theses, and Student Research
Fusarium head blight (FHB) of wheat and other small grain cereals is a devastating and economically important disease caused by members of the Fusarium graminearum species complex (FGSC). FHB poses a threat to food security and food safety, due to yield and quality reduction, as well as mycotoxin contamination. To determine the diversity of species and trichothecene genotypes of the FGSC in Nebraska, 33 wheat samples were collected from FHB-affected fields during two consecutive years (2015 and 2016) and 50 Fusarium isolates were obtained from those wheat samples. Identification of F. graminearum was attempted by PCR using UBC85 and GO …
Applications Of Femtosecond Laser Processed Metallic Surfaces: Leidenfrost Point And Thermal Stability Of Rare Earth Oxide Coatings, Anton Charles Hassebrook
Applications Of Femtosecond Laser Processed Metallic Surfaces: Leidenfrost Point And Thermal Stability Of Rare Earth Oxide Coatings, Anton Charles Hassebrook
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
In this thesis, micro/nano structured surfaces were created through the use of Femtosecond Laser Surface Processing (FLSP). In the first part of the thesis, an experimental investigation of the effects of droplet diameters and fluid properties on the Leidenfrost temperature of polished and nano/microstructured surfaces has been carried out. Leidenfrost experiments were conducted on a stainless steel 304 polished surface and a stainless steel surface which was processed by a femtosecond laser to form Above Surface Growth (ASG) nano/microstructures. Surface preparation resulted in a root mean square roughness (Rrms) of 4.8 µm and 0.04 µm on the laser …
Hierarchical Active Learning Application To Mitochondrial Disease Protein Dataset, James D. Duin
Hierarchical Active Learning Application To Mitochondrial Disease Protein Dataset, James D. Duin
School of Computing: Dissertations, Theses, and Student Research
This study investigates an application of active machine learning to a protein dataset developed to identify the source of mutations which give rise to mitochondrial disease. The dataset is labeled according to the protein's location of origin in the cell; whether in the mitochondria or not, or a specific target location in the mitochondria's outer or inner membrane, its matrix, or its ribosomes. This dataset forms a labeling hierarchy. A new machine learning approach is investigated to learn the high-level classifier, i.e., whether the protein is a mitochondrion, by separately learning finer-grained target compartment concepts and combining the results. This …