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The Pocatello Supply Depot: A History And Update, Patrick A. Darrow Jan 2020

The Pocatello Supply Depot: A History And Update, Patrick A. Darrow

Vertebrate Pest Conference Proceedings: 29th (2020)

Since the Pocatello Supply Depot (PSD) was created in 1936, the PSD has gone through many transformation and organizational changes. The most recent of these changes occurred in 2014, when the PSD transitioned from a cooperative service agreement between the U.S. Department of Agriculture (USDA) and the Greater Pocatello Chamber of Commerce, to a fully federal facility within USDA. Despite the many organizational changes, the purpose of the PSD has remained the same. The PSD manufactures and provides specialized wildlife damage management materials and services that are not readily available from commercial sources, for use by USDA Wildlife Services (WS), …


Assessing Beaver Occupancy And Dam Building Potential: A Case Study In The Umpqua Watershed Of Southwestern Oregon, Vanessa M. Petro, John Stevenson, Jimmy Taylor Jan 2020

Assessing Beaver Occupancy And Dam Building Potential: A Case Study In The Umpqua Watershed Of Southwestern Oregon, Vanessa M. Petro, John Stevenson, Jimmy Taylor

Vertebrate Pest Conference Proceedings: 29th (2020)

Interest in beaver-related restoration is growing in the western U.S. but understanding the basic ecology of American beaver and their population dynamics is often overlooked when integrating beaver into stream restoration goals. Our study investigated the spatial-temporal distribution of beaver colonies and their damming activities to better inform stream restoration projects in the West Fork Cow Creek Basin of the Umpqua Watershed in southwestern Oregon. During fall 2017, we conducted beaver activity surveys at 144 randomly selected reaches predicted to be either suitable or unsuitable for damming, but suitable for beaver occupation. We categorized beaver use at each reach using …


Automated Aerial Baiting For Invasive Brown Treesnake Control: System Overview And Program Status, Shane R. Siers, John D. Eisemann, William C. Pitt, Larry Clark, Scott M. Goetz, Robert J. Gosnell, Aaron F. Collins, Eric T. Hileman, Melia G. Nafus, Amy A. Yackel Adams, Michael C. Messaros, William G.N. Coon Jan 2020

Automated Aerial Baiting For Invasive Brown Treesnake Control: System Overview And Program Status, Shane R. Siers, John D. Eisemann, William C. Pitt, Larry Clark, Scott M. Goetz, Robert J. Gosnell, Aaron F. Collins, Eric T. Hileman, Melia G. Nafus, Amy A. Yackel Adams, Michael C. Messaros, William G.N. Coon

Vertebrate Pest Conference Proceedings: 29th (2020)

The economically and ecologically catastrophic introduction of invasive brown treesnakes to the Pacific Island of Guam has long served as a cautionary tale about the dangers of invasive species and the seeming impossibility of their management on a landscape scale. USDA Wildlife Services and federal and private partners have engineered a system for the automated manufacture and aerial delivery of toxic baits for landscape-scale suppression of brown treesnakes in large and remote forest plots. The helicopter-borne dispensing module can launch four bait cartridges per second, and a single payload of 3,600 cartridges can treat 30 ha of forest at 120 …


Understanding And Preventing Bird Damage On Dairies, Amber Adams-Progar, Karen Steensma, Stephanie A. Shwiff, Julie L. Elser, Susan Kerr, Tyler P. Caskin Jan 2020

Understanding And Preventing Bird Damage On Dairies, Amber Adams-Progar, Karen Steensma, Stephanie A. Shwiff, Julie L. Elser, Susan Kerr, Tyler P. Caskin

Vertebrate Pest Conference Proceedings: 29th (2020)

Wild birds cause significant damage to dairy farms through the consumption and spoilage of cattle feed. A survey of Washington State dairy farmers revealed approximately $14 million in bird damage losses for the Washington State dairy industry, annually. Furthermore, farms that reported the presence of more than 10,000 birds per day were more likely to report the presence of Salmonella spp. or Johne’s disease (caused by Mycobacterium avium subsp. paratuberculosis). Over the course of three years, we assessed the impact of bird populations on the presence of bacteria in bird feces and the nutritional composition of cattle feed. Five dairies …


Island Rodent Eradications: Little Things Make Big Things Happen, Araceli Samaniego-Herrera, Peter J. Kappes, Shane R. Siers Jan 2020

Island Rodent Eradications: Little Things Make Big Things Happen, Araceli Samaniego-Herrera, Peter J. Kappes, Shane R. Siers

Vertebrate Pest Conference Proceedings: 29th (2020)

Island rodent eradication is often a prerequisite for ecological restoration. These operations have been scaling up in size and complexity, and typically revolve around the thorough distribution of rodenticides in bait stations, by hand broadcast, by helicopter-borne spreading buckets, or by combinations of these methods. Many of the requirements of an eradication can be met by simply purchasing the right materials and following published best practices. However, intangible factors such as training and mindset of personnel are equally critical, and less commonly understood. We briefly review these factors and highlight issues such as the limited pool of experienced eradication practitioners, …


If At First You Don’T Eradicate: Remediating Rat Eradication Failure On Wake Atoll, Peter J. Kappes, Shane R. Siers, Kristen Rex, Chad Hanson Jan 2020

If At First You Don’T Eradicate: Remediating Rat Eradication Failure On Wake Atoll, Peter J. Kappes, Shane R. Siers, Kristen Rex, Chad Hanson

Vertebrate Pest Conference Proceedings: 29th (2020)

Island rodent eradication operations have been remarkably successful at eliminating damages caused by these harmful vertebrate pests. As efforts increase in scale and complexity, so does risk of eradication failure. In this paper we present the example of a partially successful rodent eradication project to highlight how best practices and lessons learned are being integrated to reduce risk of failure during a second attempt. In 2012 the U.S. Air Force (USAF) commissioned an attempted eradication of two rat species from Wake Atoll in the Western Pacific. Asian house rats were successfully eradicated, but it was soon confirmed that some Polynesian …


Laboratory Evaluation Of The Effectiveness Of The Fertility Control Bait Contrapest® On Wild-Captured Black Rats (Rattus Rattus), Shane Siers, Robert T. Sugihara, Israel Leinbach, Brandy R. Pyzyna, Gary Witmer Jan 2020

Laboratory Evaluation Of The Effectiveness Of The Fertility Control Bait Contrapest® On Wild-Captured Black Rats (Rattus Rattus), Shane Siers, Robert T. Sugihara, Israel Leinbach, Brandy R. Pyzyna, Gary Witmer

Vertebrate Pest Conference Proceedings: 29th (2020)

A non-toxic liquid fertility control bait for rats has recently become commercially available (ContraPest® from SenesTech, Inc.). This product contains two chemicals, both of which impair spermatogenesis in male and reduce ovulations in female rats. We tested the efficacy of this bait in wild-caught adult black rats from the island of Hawai’i in a short-term laboratory trial. A control group (n = 25) was offered placebo bait and the treatment group (n = 25) was offered fertility control bait, both ad libitum, during a 15-day introduction period and during the first of four breeding rounds, for a total of 58 …


Development And Testing Of A Matrix For Mongoose Toxic Bait: Nontoxic Bait Acceptance Cage Trials, Shane Siers, Robert T. Sugihara, Israel Leinbach, Daniel Sedgwick, Chris N. Niebuhr, Emily W. Ruell Jan 2020

Development And Testing Of A Matrix For Mongoose Toxic Bait: Nontoxic Bait Acceptance Cage Trials, Shane Siers, Robert T. Sugihara, Israel Leinbach, Daniel Sedgwick, Chris N. Niebuhr, Emily W. Ruell

Vertebrate Pest Conference Proceedings: 29th (2020)

The only pesticide currently registered for mongoose control is a product developed for rats that consists of a hard-cereal bait block. Although the active ingredient (diphacinone) is known to be highly effective for mongoose, previous studies indicate that carnivorous and omnivorous mongooses do not readily consume the hard bait matrix designed for gnawing rodents. A palatable bait matrix with a consistency more appropriate to mongoose dentition and feeding behavior will be required to develop a more effective mongoose pesticide. We evaluated the acceptance and consumption of nontoxic versions of four candidate bait matrices: FOXECUTE® and FOXSHIELD® (Animal Control Technologies, Australia; …


Feasibility Of A Successful Rat Eradication On Wake Atoll Following Initial Partial Failure: Potential Causes, Remedial Actions, And Remaining Knowledge Gaps, Chad Hanson, Kristen Rex, Peter J. Kappes, Shane R. Siers Jan 2020

Feasibility Of A Successful Rat Eradication On Wake Atoll Following Initial Partial Failure: Potential Causes, Remedial Actions, And Remaining Knowledge Gaps, Chad Hanson, Kristen Rex, Peter J. Kappes, Shane R. Siers

Vertebrate Pest Conference Proceedings: 29th (2020)

A 2012 attempt to remove two rat species (Rattus tanezumi and R. exulans) from Wake Atoll was partially successful. R. tanezumi was eradicated from all three islands (Wake, Wilkes, and Peale), and R. exulans was eradicated from Peale. However, R. exulans remained on Wake and Wilkes and have since recovered to very high densities. In 2013, a panel of experts reviewed the eradication operation and offered a list of possible causes of the partial failure. Since that time, further research has been conducted to address several of the issues identified in the review. In this paper, we conduct a current …


Placebo Bait Uptake Trial To Test Feasibility Of Polynesian Rat (Rattus Exulans) Eradication On Wake Atoll, Chris N. Niebuhr, Israel Leinbach, Thomas W. Mcauliffe, Dean K. Foster, Shane R. Siers Jan 2020

Placebo Bait Uptake Trial To Test Feasibility Of Polynesian Rat (Rattus Exulans) Eradication On Wake Atoll, Chris N. Niebuhr, Israel Leinbach, Thomas W. Mcauliffe, Dean K. Foster, Shane R. Siers

Vertebrate Pest Conference Proceedings: 29th (2020)

Rodent eradications have contributed to the recovery of many threatened species, but challenges often exist for campaigns that occur on tropical islands when compared to more temperate regions. A post-operational review of a rat eradication operation on Wake Atoll indicated that certain areas, such as those with high alternative food abundance, may have contributed to the failure to remove all Polynesian rats. We conducted a nontoxic bait uptake trial to evaluate whether the maximum prescribed bait application rate for Brodifacoum-25W rodenticide pellets was sufficient to expose all rats to a lethal dose at three sites on Wake Atoll, including around …


Roboticdeviceswithonboard Control And Related Systems And Devices, Shane Michael Farritor, Erik Mumm, Philip Chu, Nishant Kumar, Jason Dumpert, Yutaka Tsutano Jan 2020

Roboticdeviceswithonboard Control And Related Systems And Devices, Shane Michael Farritor, Erik Mumm, Philip Chu, Nishant Kumar, Jason Dumpert, Yutaka Tsutano

Department of Mechanical and Materials Engineering: Faculty Publications

The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various modular medical devices for in vivo medical procedures.


Comparative Analysis Of Single-Cell Transcriptomics In Human And Zebrafish Oocytes, Handan Can, Sree K. Chanumolu, Elena Gonzalez-Muñoz, Sukumal Prukudom, Hasan H. Otu, Jose Cibelli Jan 2020

Comparative Analysis Of Single-Cell Transcriptomics In Human And Zebrafish Oocytes, Handan Can, Sree K. Chanumolu, Elena Gonzalez-Muñoz, Sukumal Prukudom, Hasan H. Otu, Jose Cibelli

Department of Electrical and Computer Engineering: Faculty Publications

Background: Zebrafish is a popular model organism, which is widely used in developmental biology research. Despite its general use, the direct comparison of the zebrafish and human oocyte transcriptomes has not been well studied. It is significant to see if the similarity observed between the two organisms at the gene sequence level is also observed at the expression level in key cell types such as the oocyte.

Results: We performed single-cell RNA-seq of the zebrafish oocyte and compared it with two studies that have performed single-cell RNA-seq of the human oocyte. We carried out a comparative analysis of genes expressed …


Cdc42-Dependent Transfer Of Mir301 From Breast Cancer-Derived Extracellular Vesicles Regulates The Matrix Modulating Ability Of Astrocytes At The Blood–Brain Barrier, Golnaz Morad, Cassandra C. Daisy, Hasan H. Otu, Towia A. Libermann, Simon T. Dillon, Marsha A. Moses Jan 2020

Cdc42-Dependent Transfer Of Mir301 From Breast Cancer-Derived Extracellular Vesicles Regulates The Matrix Modulating Ability Of Astrocytes At The Blood–Brain Barrier, Golnaz Morad, Cassandra C. Daisy, Hasan H. Otu, Towia A. Libermann, Simon T. Dillon, Marsha A. Moses

Department of Electrical and Computer Engineering: Faculty Publications

Breast cancer brain metastasis is a major clinical challenge and is associated with a dismal prognosis. Understanding the mechanisms underlying the early stages of brain metastasis can provide opportunities to develop efficient diagnostics and therapeutics for this significant clinical challenge. We have previously reported that breast cancer-derived extracellular vesicles (EVs) breach the blood–brain barrier (BBB) via transcytosis and can promote brain metastasis. Here, we elucidate the functional consequences of EV transport across the BBB. We demonstrate that brain metastasis-promoting EVs can be internalized by astrocytes and modulate the behavior of these cells to promote extracellular matrix remodeling in vivo. We …


Ieee Access Special Section Editorial: Green Signal Processing For Wireless Communicationsand Networking, Wen-Long Chin, David Shiung, Yi Qian, Woongsup Lee, Andres Kwasinki, Yansha Deng Jan 2020

Ieee Access Special Section Editorial: Green Signal Processing For Wireless Communicationsand Networking, Wen-Long Chin, David Shiung, Yi Qian, Woongsup Lee, Andres Kwasinki, Yansha Deng

Department of Electrical and Computer Engineering: Faculty Publications

No abstract provided.


Holistic Health And Fitness (This Item Is Published With Basic Incl C1), United States Army Jan 2020

Holistic Health And Fitness (This Item Is Published With Basic Incl C1), United States Army

United States Army: Field Manuals

Holistic Health and Fitness (This Item Is Published with Basic Incl C1), United States Army Field Manual FM 7-22, This publication supersedes chapters 1–6 and Appendix D of FM 7-22 dated October 26, 2012


Effect Of Urban Green Space On Urban Populations., Jack Mensinger Jan 2020

Effect Of Urban Green Space On Urban Populations., Jack Mensinger

Department of Environmental Studies: Undergraduate Student Theses

As the world's population continues to urbanize, population density increases and people endure the ever-increasing speed of the urban environment. The need to focus on mental and physical health becomes ever more critical as daily routines may not fulfill urban residents' basic needs. The bulk of work studying the relationship between green space, mental, and physical wellness, have had a narrow scope in their assessment of the benefits of green space. Previous studies focused either on the human interaction or the spaces utilities as a corridor and a habitat for flora and fauna. We utilized a systematic literature review to …


Diatom Morphology In Light Of A Changing Climate: A Focus On Aulacoseira Crenulate, Brighid Welchans Jan 2020

Diatom Morphology In Light Of A Changing Climate: A Focus On Aulacoseira Crenulate, Brighid Welchans

Department of Environmental Studies: Undergraduate Student Theses

Fossilized diatoms are arguably the most vital proxy record utilized in paleolimnology. Diatoms are unicellular microalgae that are the basis of countless food webs, are invaluable bioindicators, and generate nearly a quarter of global net primary productivity. Diatoms are affected by a variety of environmental factors but there is relatively little research on how environmental conditions impact diatom valve morphology, and in particular whether there is a correlation between incoming light and diatom pore morphology. This report focuses on the Amazon lowland lake Garzacocha, and analyzes the relationship between light levels and the corresponding size of Aulacoseira crenulata pores. We …


Agronomic Utilization Of Precipitated Calcium Carbonate—Effect Of Pcc On Sugar Beet Root Aphid Control And Herbicide Dose Response Of Kochia Grown On Pcc Piles, Murali Darapuneni, Gary W. Hergert, Jeff Bradshaw, Robert Wilson, Abdul Aqeel, Robert Harveson, Rex Nielsen, Leonard Lauriault Jan 2020

Agronomic Utilization Of Precipitated Calcium Carbonate—Effect Of Pcc On Sugar Beet Root Aphid Control And Herbicide Dose Response Of Kochia Grown On Pcc Piles, Murali Darapuneni, Gary W. Hergert, Jeff Bradshaw, Robert Wilson, Abdul Aqeel, Robert Harveson, Rex Nielsen, Leonard Lauriault

Panhandle Research and Extension Center

Agricultural use of precipitated calcium carbonate (PCC), a byproduct of sugar clarification process, as a possible source of nutrients and pest and disease control in sugar beet (Beta vulgaris subsp. vulgaris.) needs a careful examination of the risk and benefit assessment at various levels of management and production. A series of controlled environment studies were conducted in Scottsbluff, NE, to assess the 1) effect of PCC on root aphids in sugar beet, and 2) risk of the weed kochia spreading by applying PCC to agricultural land and its chemical control strategy, by conducting various dose-response studies. A replicated lab study …


20 Is Plenty: The Most Infamous Of The Invasive Species, Giancarlo V. Maddaloni Jan 2020

20 Is Plenty: The Most Infamous Of The Invasive Species, Giancarlo V. Maddaloni

Department of Entomology: Distance Master of Science Projects

This informational resource was created to assist the general public in learning about the importance of invasive insects and provide help in identifying some of the most dangerous among them. This guide will also provide current information about prevention and control of these insects along with what high risk items travelers should be careful of returning with from abroad to control the spread of these pests. This resource also covers inter-state as well as intra-state pests of concern, illustrating the importance of adhering to quarantine guidelines while traveling through these regions. Whether or not this pest has become established, it …


Apopka Insect Field Guide, Sarah Parker Jan 2020

Apopka Insect Field Guide, Sarah Parker

Department of Entomology: Distance Master of Science Projects

For my master's project I created a printable insect field guide specific to my area for use by the local elementary and middle schools. My property is located near both Lakeville Elementary School and Piedmont Lakes Middle School, therefore insects collected in my garden should closely approximate the insects that could potentially be seen at either school. A targeted insect guide will help facilitate any number of observational activities and may encourage the schools to plant insect friendly vegetation to increase their abundance of insects. My goal is for this teaching tool to encourage local teachers to include insect education …


Use Of Otolith Chemistry To Assess Recruitment And Habitat Use Of A White Bass Fishery In A Nebraska Reservoir, Matthew A. Perrion, Mark A. Kaemingk, Keith D. Koupal, Casey W. Schoenebeck, Nate A. Bickford Jan 2020

Use Of Otolith Chemistry To Assess Recruitment And Habitat Use Of A White Bass Fishery In A Nebraska Reservoir, Matthew A. Perrion, Mark A. Kaemingk, Keith D. Koupal, Casey W. Schoenebeck, Nate A. Bickford

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Managing fisheries that exhibit variable annual recruitment is challenging, and maintenance stockings are often prescribed to minimize interannual population variation. Maintenance stockings are costly and may not be necessary if sufficient natural recruitment is occurring. Therefore, developing tools and techniques that can collectively assess hatching origin and subsequent habitat use of individuals would be valuable. Herein, we aimed to assess the efficacy of otolith chemistry techniques to (1) determine whether there was evidence of natural recruitment within an annually stocked white bass population and (2) examine the potential to describe spatial reservoir use of these age-0 fish. A sample of …


Flash Drought Development And Cascading Impacts Associated With The 2010 Russian Heatwave, J. Christian, J. B. Basara, E. D. Hunt, J. A. Otkin, X. Xiao Jan 2020

Flash Drought Development And Cascading Impacts Associated With The 2010 Russian Heatwave, J. Christian, J. B. Basara, E. D. Hunt, J. A. Otkin, X. Xiao

School of Natural Resources: Faculty Publications

No abstract provided.


Thriving Nebraska: Key Drivers For Community Economic Vitality, Laura E. Young, Mary Garbacz, Michael J. Boehm, Matthew Morton, Marilyn R. Schlake, Katie Bresnahan, Paul Springer, Alex Voichoskie, Megan Kelley, Emily Frenzen, Jill O'Donnell, Haley Ehrke, Chris Chizinski, Surin Kim, Tom Field, Taylor Nuss, John Erixson, Simanti Banerjee, Lexi Kaiser, Isamail Dweikat, Taylor Ruth, Alice Akers, Travis Mulliniks, Nathan Conner, Kathleen Lodl, Terry Howell, Matt Allmand, Demi Striglos, Ed Cahoon, Mark Wilkins Jan 2020

Thriving Nebraska: Key Drivers For Community Economic Vitality, Laura E. Young, Mary Garbacz, Michael J. Boehm, Matthew Morton, Marilyn R. Schlake, Katie Bresnahan, Paul Springer, Alex Voichoskie, Megan Kelley, Emily Frenzen, Jill O'Donnell, Haley Ehrke, Chris Chizinski, Surin Kim, Tom Field, Taylor Nuss, John Erixson, Simanti Banerjee, Lexi Kaiser, Isamail Dweikat, Taylor Ruth, Alice Akers, Travis Mulliniks, Nathan Conner, Kathleen Lodl, Terry Howell, Matt Allmand, Demi Striglos, Ed Cahoon, Mark Wilkins

Strategic Discussions for Nebraska

Thriving Nebraska: Key Drivers for Community Economic Vitality

When we think about community vitality, we consider the factors that influence the quality of life and the prosperity of life for people in those communities. We have a responsibility in our research and discovery agenda to push the bounds and discover new information. Then, we put this new information to work in our state.


The Effect Of Presenting Relative Calorie Information On Calories Ordered, Christopher Gustafson, Eliana Zeballos Jan 2020

The Effect Of Presenting Relative Calorie Information On Calories Ordered, Christopher Gustafson, Eliana Zeballos

Department of Agricultural Economics: Faculty Publications

In this research, we tested the effect of a novel method of presenting calorie information—highlighting relative differences in calories among ingredients. We conducted an online hypothetical food choice experiment where 633 participants selected the ingredients for a sandwich from five categories: meat/protein, cheese, spread/ dressing, bread, and vegetables. Each participant was randomly assigned to one of four calorie information conditions: 1) a condition in which no information about calories was provided, 2) a condition in which calorie information was provided for each ingredient, 3) a condition in which calorie information was presented relative to the highest calorie item, and 4) …


Introduction To Metaeconomics, Gary D. Lynne Jan 2020

Introduction To Metaeconomics, Gary D. Lynne

Department of Agricultural Economics: Faculty Publications

Metaeconomics is fundamentally about the problem of having too much emphasis on the Market or too much emphasis on the Government. It is about the essential need to bring empirical reality and ethics into finding balance: It is essential to achieving a good capitalism. Why? Well, because of the natural tendency to excessive Greed. As DeWaal (2009) would have it, we live in an age of Empathy: Ego based Greed is out. The Greed needs to be tempered, balanced, and perhaps bounded, with Empathy-based ethics. And, as Metaeconomics makes clear, it is because there is a dual nature of human …


Camelid Fleece And The Hidden Histories Of Colors In The Andes, Penelope Dransart Jan 2020

Camelid Fleece And The Hidden Histories Of Colors In The Andes, Penelope Dransart

Textile Society of America: Symposium Proceedings

This article explores the significance of natural fleece colors that are often hidden by dyeing processes. The earliest domesticated alpacas and llamas probably resembled vicuñas and guanacos, their wild counterparts. By 3000 years ago, differences were beginning to emerge in the coats of alpacas and llamas. Dyers, spinners, and weavers learned to exploit these variations to complement and extend the range of possibilities offered through the use of dyed yarns. The evidence from the Siguas and Nasca cultural traditions considered here is both direct and indirect, taking into account textile remains and the depiction of camelids on ceramics. It indicates …


Evaluating Gene Drive Approaches For Public Benefit, Michael R. Santos Jan 2020

Evaluating Gene Drive Approaches For Public Benefit, Michael R. Santos

United States Public Health Resources

Gene drive approaches—those which bias inheritance of a genetic element in a population of sexually reproducing organisms—have the potential to provide important public benefits. The spread of selected genetic elements in wild populations of organisms may help address certain challenges, such as transmission of vector-borne human and animal diseases and biodiversity loss due to invasive animals. Adapting various naturally occurring gene drive mechanisms to these aims is a long-standing research area, and recent advances in genetics have made engineering gene drive systems significantly more technically feasible. Gene drive approaches would act through changes in natural environments, thus robust methods to …


Adaptive In Vivo Device For Theranostics Of Inflammation: Real-Time Monitoring Of Interferon-Γ And Aspirin, Chaomin Cao, Ronghua Jin, Hui Wei, Zhongning Liu, Shengnan Ni, Guo Jun Liu, Howard A. Young, Xin Chen, Guozhen Liu Jan 2020

Adaptive In Vivo Device For Theranostics Of Inflammation: Real-Time Monitoring Of Interferon-Γ And Aspirin, Chaomin Cao, Ronghua Jin, Hui Wei, Zhongning Liu, Shengnan Ni, Guo Jun Liu, Howard A. Young, Xin Chen, Guozhen Liu

United States Public Health Resources

Cytokines mediate and control immune and inflammatory responses. Complex interactions exist among cytokines, inflammation, and the innate and adaptive immune responses in maintaining homeostasis, health, and well-being. On-demand, local delivery of anti-inflammatory drugs to target tissues provides an approach for more effective drug dosing while reducing the adverse effects of systemic drug delivery. This work demonstrates a proof-of-concept theranostic approach for inflammation based on analyte-kissing induced signaling, whereby a drug (in this report, aspirin) can be released upon the detection of a target level of a proinflammatory cytokine (i.e., interferon-γ (IFN-γ)) in real time. The structure-switching aptamer-based biosensor described here …


2020 Focused Updates To The Asthma Management Guidelines: Clinician's Guide Jan 2020

2020 Focused Updates To The Asthma Management Guidelines: Clinician's Guide

United States Natonal Institutes of Health: Materials

This Clinician’s Guide summarizes the 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention group.


2020 Focused Updates To The Asthma Management Guidelines: At-A-Glance Guide Jan 2020

2020 Focused Updates To The Asthma Management Guidelines: At-A-Glance Guide

United States Natonal Institutes of Health: Materials

This At-A-Glance Guide describes a treatment management approach based on recommendations from the 2020 Focused Updates to the Asthma Management Guidelines.