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“Emerging” Parasitic Infections In Arctic Ungulates, Susan J. Kutz, Eric P. Hoberg, John Nagy, Lydden Polley, Brett Elkin Apr 2004

“Emerging” Parasitic Infections In Arctic Ungulates, Susan J. Kutz, Eric P. Hoberg, John Nagy, Lydden Polley, Brett Elkin

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Important drivers for emergence of infectious disease in wildlife include changes in the environment, shrinking habitats or concentration of wildlife, and movement of people, animals, pathogens, or vectors. In this paper we present three case-studies of emerging parasitic infections and diseases in ungulates in the Canadian north. First we discuss climate warming as an important driver for the emergence of disease associated with Umingmakstrongylus pallikuukensis, a nematode lungworm of muskoxen. Then we examine how Protostrongylus stilesi, the sheep lungworm, emerged (or re-emerged) in muskoxen after re-introduction of this host into its historical range made it sympatric with Dall’s …

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Rocky Mountain Wolf Recovery 2004 Annual Report Mar 2004

Rocky Mountain Wolf Recovery 2004 Annual Report

Rocky Mountain Wolf Recovery: Annual Reports

The gray wolf (Canis lupus) population in the Northern Rocky Mountain (NRM) states (Idaho, Montana, and Wyoming) continued to increase in distribution and numbers (Figure 1, Tables 4a, 4b). Estimates of wolf numbers at the end of 2004 were 452 wolves in the Central Idaho Recovery Area (CID), 324 in the Greater Yellowstone Recovery Area (GYA), and 59 in the Northwest Montana Recovery Area (NWMT) for a total of 835 wolves (Figure 1, Table 4a). By state boundaries, there were an estimated 422 wolves in the state of Idaho, 260 in Wyoming and 153 in Montana (Table 4b). …

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Causes Of Proteolytic Degradation Of Secreted Recombinant Proteins Produced In Methylotrophic Yeast Pichia Pastoris: Case Study With Recombinant Ovine Interferon-Τ, Mehmet İnan, Michael M. Meagher, Bradley A. Plantz, Jayanta Sinha Mar 2004

Causes Of Proteolytic Degradation Of Secreted Recombinant Proteins Produced In Methylotrophic Yeast Pichia Pastoris: Case Study With Recombinant Ovine Interferon-Τ, Mehmet İnan, Michael M. Meagher, Bradley A. Plantz, Jayanta Sinha

Papers in Biochemical Engineering

It was observed that during fermentative production of recombinant ovine interferon-τ (r-oIFN-τ) in Pichia pastoris, a secreted recombinant protein, the protein was degraded increasingly after 48 h of induction and the rate of degradation increased towards the end of fermentation at 72 h, when the fermentation was stopped. Proteases, whose primary source was the vacuoles, was found in increasing levels in the cytoplasm and in the fermentation broth after 48 h of induction and reached maximal values when the batch was completed at 72 h. Protease levels at various cell fractions as well as in the culture supernatant were …

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Coyote Attacks: An Increasing Suburban Problem, Robert M. Timm, Rex O. Baker, Joe R. Bennett, Craig C. Coolahan Mar 2004

Coyote Attacks: An Increasing Suburban Problem, Robert M. Timm, Rex O. Baker, Joe R. Bennett, Craig C. Coolahan

Vertebrate Pest Conference Proceedings: 21st (2004)

Coyote attacks on humans and pets have increased within the past 5 years in California. We discuss documented occurrences of coyote aggression and attacks on people, using data from USDA Wildlife Services, the California Department of Fish & Game, and other sources. Forty-eight such attacks on children and adults were verified from 1998 through 2003, compared to 41 attacks during the period 1988 through 1997; most incidents occurred in Southern California near the suburban-wildland interface. Attack incidents are typically preceded by a sequence of increasingly bold coyote behaviors, including: nighttime coyote attacks on pets; sightings of coyotes in neighborhoods at …

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Nebraska Vine Lines, Vol. Vii, No. 2, March/April 2004 Mar 2004

Nebraska Vine Lines, Vol. Vii, No. 2, March/April 2004

Nebraska Vine Lines (2003–2006)

Contents

• Seventh Annual Nebraska Winery & Grape Growers Forum and Trade Show “Best Yet”

• Highlights from Wineries Unlimited

• Australia: Grape quality “not related to yield”

• UNVPAC Survey Results

• “Nebraska’s Largest Winery receives Enterprising Gambler Award”

• Speakers Bureau Slide Presentation

• Fall Workshop: “Instrumentation for Vineyards and Wineries”

• Grape Growing Environments in Nebraska –Winegrapes in Uncertain Climates by William Waltman

• The Vinifera Zone

• Major Grape Growing Zones

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Nebline, March 2004 Mar 2004

Nebline, March 2004

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

All-American Selections: 72 Years of Award-Winning Plants
Nature, the Ultimate Recycler
Scrap Tire Collection Announced
Guidelines for Farm Debt
Roosting Starlings are a Nasty Problem
UNL Beekeeping Programs for 2004
Cats in the Neighborhood Can be a Nuisance, Harmful to Local Wildlife
Ants on the Web
Eating GREEN on St. Patrick’s Day
Easy PB & Banana Waffles Recipe
Oh Those Darn Portion Sizes
Tea Time! - Brewing a Tasty (& Healthy!) Cup of Tea
Eating Dairy Products May Help Children Control Their Weight
President’s Notes – Janet’s Jargon
Household Hints
FCE News & Events
National Poison Prevention Week is March …

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Tuberculosis, John B. Kaneene, Charles O. Thoen Mar 2004

Tuberculosis, John B. Kaneene, Charles O. Thoen

Michigan Bovine Tuberculosis Bibliography and Database

Tuberculosis is a term that encompasses various diseases caused by bacteria of the Mycobacterium tuberculosis complex, including M tuberculosis, M bovis, M africanum, and other mycobacterial species. Whereas M tuberculosis infection is largely spread from human to human, M bovis infection has been identified as a zoonotic disease with most cases of human infection attributable to animal sources. The mycobacteria other than tuberculosis complex (MOTT), which includes M avium subsp avium and M avium subsp intracellulare isolated from animals, has been isolated from immune-compromised humans (ie, those with human immunodeficiency virus [HIV] infection), but seldom from immunocompetent humans. Recently, …

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Inoculum Size Effect In Dimorphic Fungi: Extracellular Control Of Yeast-Mycelium Dimorphism In Ceratocystis Ulmi, Jacob M. Hornby, Sarah M. Jacobitz-Kizzier, Donna J. Mcneel, Ellen C. Jensen, David S. Treves, Kenneth W. Nickerson Mar 2004

Inoculum Size Effect In Dimorphic Fungi: Extracellular Control Of Yeast-Mycelium Dimorphism In Ceratocystis Ulmi, Jacob M. Hornby, Sarah M. Jacobitz-Kizzier, Donna J. Mcneel, Ellen C. Jensen, David S. Treves, Kenneth W. Nickerson

Papers in Microbiology

We studied the inoculum size effect in Ceratocystis ulmi, the dimorphic fungus that causes Dutch elm disease. In a defined glucose-proline-salts medium, cells develop as budding yeasts when inoculated at >106 spores per ml and as mycelia when inoculated at type, age of the spores, temperature, pH, oxygen availability, trace metals, sulfur source, phosphorous source, or the concentration of glucose or proline. Similarly, it was not influenced by added adenosine, reducing agents, methyl donors, amino sugars, fatty acids, or carbon dioxide. Instead, growing cells excreted an unknown quorum-sensing factor that caused a morphological shift from mycelia to budding yeasts. …

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Age-Of-Dam Adjustment Factors For Birth And Weaning Weight Records Of Beef Cattle: A Review, Janice M. Rumpf, L. Dale Van Vleck Feb 2004

Age-Of-Dam Adjustment Factors For Birth And Weaning Weight Records Of Beef Cattle: A Review, Janice M. Rumpf, L. Dale Van Vleck

Department of Animal Science: Faculty Publications

Age-of-dam adjustment factors are used to pre-adjust birth and weaning weight data for national beef cattle genetic evaluations. Adjustments are used in order to make the means of the different age-of-dam subclasses similar so that a fair comparison of animals can be performed. A review was made of various research studies that have estimated age-of-dam adjustment factors for birth weight and weaning weight of beef cattle. In general, birth weight age-of-dam adjustment factors are the same across the sexes, but weaning weight age-of-darn adjustment factors differ across the sexes, with heifer calves receiving smaller adjustments than their male counterparts. Additionally, …

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Piggybac Transformation Of The New World Screwworm, Cochliomyia Hominivorax, Produces Multiple Distinct Mutant Strains, M.L. Allen, A.M. Handler, Dennis Berkebile, S.R. Skoda Feb 2004

Piggybac Transformation Of The New World Screwworm, Cochliomyia Hominivorax, Produces Multiple Distinct Mutant Strains, M.L. Allen, A.M. Handler, Dennis Berkebile, S.R. Skoda

Department of Entomology: Faculty Publications

Sterile insect technique (SIT) programs are designed to eradicate pest species by releasing mass-reared, sterile insects into an infested area. The first major implementation of SIT was the New World Screwworm Eradication Program, which successfully eliminated the New World screwworm (NWS), Cochliomyia hominivorax (Coquerel) (Diptera: Calliphoridae), from the Continental US, Mexico and much of Central America. Ionizing radiation is currently used for sterilization, but transgenic insect techniques could replace this method, providing a safer, more cost-effective alternative. Genetic transformation methods have been demonstrated in NWS, and verified by Southern blot hybridization, PCR and sequencing of element insertion junctions. A lethal …

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Coyotes In Yellowstone National Park: The Influence Of Dominance On Foraging, Territoriality, And Fitness, Eric M. Gese Feb 2004

Coyotes In Yellowstone National Park: The Influence Of Dominance On Foraging, Territoriality, And Fitness, Eric M. Gese

United States Department of Agriculture Wildlife Services: Staff Publications

The coyote, is an opportunistic, generalist predator that has expanded its distribution to most of North America and is probably one of the most widely researched canids. Yet, its typically nocturnal, secretive behavior mean there have been only two studies-both in Grand Teton National Park, Wyoming-based on direct observation of wild coyotes (Camenzind 1978b; Bekoff and Wells 1986). The coyote population in YNP has not been persecuted for several decades, and thus is tolerant of humans to an extent that has facilitated our studies of how coyotes deal with fluctuations in temperature, snow depth, snow-pack hardness, and food availability (e.g. …

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Effects Of Forage Nutritional Quality (Energy And Protein) On Deer Acceptance Of Foods Containing Secondary Metabolites, Dale L. Nolte, Bruce A. Kimball, Kelly R. Perry, Juan J. Villalba, Frederick D. Provenza Feb 2004

Effects Of Forage Nutritional Quality (Energy And Protein) On Deer Acceptance Of Foods Containing Secondary Metabolites, Dale L. Nolte, Bruce A. Kimball, Kelly R. Perry, Juan J. Villalba, Frederick D. Provenza

United States Department of Agriculture Wildlife Services: Staff Publications


Deer foraging on tree seedlings is recognized as the most widespread detriment to reforestation efforts. Non-lethal approaches to reduce deer damage to seedlings are highly desirable. Avoidance of natural secondary metabolites contained in conifers may provide feasible means to develop non-lethal measures. Other studies have demonstrated that sheep and goats fed diets with high protein-to-energy ratios, or allowed to select between concentrates high in either energy or protein, ate much more of a high-terpene diet and of a high-tannin diet than when they were fed diets high in energy-to-protein ratios. Thus, manipulating foraging options for deer may impact their ability …

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Genetic Relationships Between Sex-Specific Traits In Beef Cattle: Mature Weight, Weight Adjusted For Body Condition Score, Height And Body Condition Score Of Cows, And Carcass Traits Of Their Steer Relatives, K. A. Nephawe, L. V. Cundiff, M. E. Dikeman, J. D. Crouse, L. Dale Van Vleck Feb 2004

Genetic Relationships Between Sex-Specific Traits In Beef Cattle: Mature Weight, Weight Adjusted For Body Condition Score, Height And Body Condition Score Of Cows, And Carcass Traits Of Their Steer Relatives, K. A. Nephawe, L. V. Cundiff, M. E. Dikeman, J. D. Crouse, L. Dale Van Vleck

Department of Animal Science: Faculty Publications

Data from the first four cycles of the Germplasm Evaluation Program at the U.S. Meat Animal Research Center (USMARC) were used to investigate genetic relationships between mature weight (MW, n = 37,710), mature weight adjusted for body condition score (AMW, n = 37,676), mature height (HT, n = 37,123), and BCS (n = 37,676) from 4- to 8-yr old cows (n = 1,800) and carcass traits (n = 4,027) measured on their crossbred paternal half-sib steers. Covariance components among traits were estimated using REML. Carcass traits were adjusted for age at slaughter. Estimates of heritability for hot carcass weight (HCWT); …

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University Of Nebraska–Lincoln Extension Connect, February 2004 Feb 2004

University Of Nebraska–Lincoln Extension Connect, February 2004

Connect (University of Nebraska-Lincoln Extension)

Inside this issue:

Pg. 3 Latino Voices Pg. 4 Environmental stewardship Pg. 7 Water use reduced

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Ard News February 2004 Feb 2004

Ard News February 2004

Agricultural Research Division: News and Annual Reports

CONTENTS:
Comments from the Dean
Hatch and State Projects
FY 2004 CSREES Appropriation and the President's FY 2005 Budget
117th ARD Annual Report
Federal Earmark Grants – FY 2004
Endeavors
Grants and Contracts Received December 2003 and January 2004
Proposals Submitted for Federal Grants
New or Revised Projects
Fall 2003 Graduate Census

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Agricultural Biotechnology Training For Extension Educators, Susan Fritz, Sarah Ward, Patrick Byrne, Kristyn Harms, Deana Namuth Feb 2004

Agricultural Biotechnology Training For Extension Educators, Susan Fritz, Sarah Ward, Patrick Byrne, Kristyn Harms, Deana Namuth

Department of Agricultural Leadership, Education, and Communication: Faculty Publications

Recent advances in plant biotechnology have led to significant changes in crop varieties and cropping systems in the United States, in particular the rapidly expanding cultivation of transgenic or genetically modified (GM) crops (Liu, 1999). Such crops, which contain artificially inserted genes, have been hailed as a major advance in agricultural technology and simultaneously condemned as a grave threat to the environment and to human health. In Europe, which represents a significant market for U.S. agricultural producers, widespread and vehement public opposition has effectively shut down importation and domestic production of GM crops, while in the U.S. public uncertainty is …

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Nebline, February 2004 Feb 2004

Nebline, February 2004

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Lancaster County Benefits from a Year-Round Farmer’s Market
Computerized Financial Record Keeping Workshops
Check Condition of Stored Grain
The Dream of Country Living
Attracting Birds with Proper Habitat
Urban Agriculture is Branch of Modern Sustainable Agriculture
Power Tool Safety
See “Red” on Valentine’s Day
Strawberry Sauce Recipe
Golden Apple Oatmeal Recipe
A Healthy Plate - What Does It Look Like?
No-Salt Sloppy Joe Seasoning Mix
President’s Notes – Janet’s Jargon
Household Hints: Keep Heating & Cooling Costs Under Control
FCE News & Events
Sharing Meals Important to Building Family Unity
Ease Parenting During Teen Years With Communication, Involvement
A Caring …

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Fatty Acid Composition And Oxidation Of Lipids In Korean Catfish, K. T. Hwang, J. E. Kim, S. G. Kang, S. T. Jung, H. J. Park, Curtis L. Weller Feb 2004

Fatty Acid Composition And Oxidation Of Lipids In Korean Catfish, K. T. Hwang, J. E. Kim, S. G. Kang, S. T. Jung, H. J. Park, Curtis L. Weller

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This study determined the lipid content and FA composition of muscle and a mixture of muscle and viscera from Korean catfish as well as lipid oxidation and hydrolysis. Lipid content and FA compositions in Korean catfish, which were purchased every month or two during September 1999–July 2000, were analyzed. Lipid oxidation and hydrolysis were determined as PV, thiobarbituric acid value, and FFA in the muscle and the mixture during storage at 2°C for 12 d and –14°C for 9 wk. Lipid contents of the muscle and the mixture were 3.2 (w/w) and 5.4%, respectively. Oleic acid was the most abundant …

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Prediction Of Leaf/Stem Ratio Using Near-Infrared Reflectance Spectroscopy (Nirs): A Technical Note, Alexander J. Smart, Walter H. Schacht, Lowell E. Moser, Jerry D. Volesky Feb 2004

Prediction Of Leaf/Stem Ratio Using Near-Infrared Reflectance Spectroscopy (Nirs): A Technical Note, Alexander J. Smart, Walter H. Schacht, Lowell E. Moser, Jerry D. Volesky

Department of Agronomy and Horticulture: Faculty Publications

Leaf/stem ratio of grass stands is an important factor affecting diet selection, quality, and forage intake. Determination of leaf/stem ratio involves a labor-intensive process of hand separating leaf and stem fractions. Our objectives in this study were to evaluate leaf/stem ratio prediction using near-infrared reflectance spectroscopy (NIRS) in monocultures of big bluestem (Andropogon gerardii Vitman), switch- grass (Panicum virgatum L.), intermediate wheatgrass [Thinopyrum intermedian (Host) Barkw. & D.R. Dewey], and smooth bromegrass (Bromus inermis Leyss.). Samples of each species were hand-clipped from monocultures at four locations throughout Nebraska in the 1997 and 1998 growing seasons. Ground …

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Understanding Mental Health Needs Of Southeast Asian Refugees: Historical, Cultural, And Contextual Challenges, Eugenia Hsu, Corrie A. Davies, David J. Hansen Jan 2004

Understanding Mental Health Needs Of Southeast Asian Refugees: Historical, Cultural, And Contextual Challenges, Eugenia Hsu, Corrie A. Davies, David J. Hansen

Department of Psychology: Faculty Publications

Research and clinical information pertaining to mental health needs of Asians residing in the United States is limited but growing. There is a tendency to group all persons of Asian descent together and, therefore, the empirical literature does not sufficiently address the mental health needs in specific subgroups. The focus of this article is to understand the mental health needs of one subgroup of Asians-Southeast Asian refugees (SEAR). The main purpose is to review the relevant literature pertaining to Southeast Asian refugees’ experiences and to understand the manifestation of psychiatric disorders by examining historical, cultural, and contextual challenges. Despite the …

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Forage & Grazing Lands: Morphological Characteristics Of Big Bluestem And Switchgrass Plants Divergently Selected For Seedling Tiller Number, Alexander J. Smart, Lowell E. Moser, Kenneth P. Vogel Jan 2004

Forage & Grazing Lands: Morphological Characteristics Of Big Bluestem And Switchgrass Plants Divergently Selected For Seedling Tiller Number, Alexander J. Smart, Lowell E. Moser, Kenneth P. Vogel

Department of Agronomy and Horticulture: Faculty Publications

Selection at the seedling stage in grass breeding would be useful if seedling traits were correlated to desired agronomic traits of mature plants. Objectives of this study were to determine if seedlings from big bluestem (Andropogon gerardii Vitman) and switchgrass (Panicumvirgatum L.) populations that differ genetically in seedling tiller num- ber differ in mature plant (i) morphological characteristics, (ii) forage yield managed by a three-cut harvest system or a single end-of-season harvest, and (iii) leaf elongation rate. Field experiments were conducted on a Kennebec silt loam soil (fine-silty, mixed, superactive, mesic Cumulic Hapludolls). In addition, greenhouse studies were …

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2004 Nebraska Swine Report Jan 2004

2004 Nebraska Swine Report

Nebraska Swine Reports

Contents

Nutrition
Body Composition, Protein Deposition, and Efficiency of Lysine Utilization of Growing Pigs Fed Crystalline or Protein-Bound Lysine
Dietary Antimicrobials in a Wean-to-Finish Facility
Update on Omega-3 Fatty Acids and Litter Size in Swine
Effects of Sow Dietary Glutamine Supplementation on Sow and Litter Performance, Subsequent Weanling Pig Performance, and Intestinal Development after an Immune Challenge
Energy and Nitrogen Utilization of Corn Rootworm Protected Corn (Event MON 863) and Similar Non-Transgenic Corn in Young Pigs
Effect of Increasing Dietary Crude Protein Concentration on Growth Performance and Serum Insulin-Like Growth Factor-I Concentration

Genetics
Different Biological Responses of Pigs of Two …

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Nebraska 2004 Beef Cattle Report (Complete Volume) Jan 2004

Nebraska 2004 Beef Cattle Report (Complete Volume)

Nebraska Beef Cattle Reports

Contents

Cow-Calf
An Evaluation of Economic Efficiencies of Two Beef Systems from Calving to Harvest
A System for Wintering Spring-calving Bred Heifers Without Feeding Hay
Effect of Gestation and Supplementation on Intake of Low-quality Forage

Grazing
A Review of Corn Stalk Grazing on Animal Performance and Crop Yield
Feed Values for Annual Forages in Western Nebraska
Urea Inclusion in Forage Based Diets Containing Dried Distillers Grains
Effect of Distillers Grains or Corn Supplementation Frequency on Forage Intake and Digestibility
Dried Distillers Grains as a Grazed Forage Supplement

Finishing
Effects of Corn Bran and Degradable Protein Source on Microbial Protein Estimated …

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Identification Of Trace Element-Containing Proteins In Genomic Databases, Vadim N. Gladyshev, Gregory V. Kryukov, Dmitri E. Fomenko, Dolph L. Hatfield Jan 2004

Identification Of Trace Element-Containing Proteins In Genomic Databases, Vadim N. Gladyshev, Gregory V. Kryukov, Dmitri E. Fomenko, Dolph L. Hatfield

Vadim Gladyshev Publications

Development of bioinformatics tools provided researchers with the ability to identify full sets of trace element–containing proteins in organisms for which complete genomic sequences are available. Recently, independent bioinformatics methods were used to identify all, or almost all, genes encoding selenocysteine-containing proteins in human, mouse, and Drosophila genomes, characterizing entire selenoproteomes in these organisms. It also should be possible to search for entire sets of other trace element–associated proteins, such as metal-containing proteins, although methods for their identification are still in development.

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Gudmundsen Sandhills Laboratory Open House, John Owens Jan 2004

Gudmundsen Sandhills Laboratory Open House, John Owens

John Owens: Speeches and Appearances

What a pleasure it is to be here with you today at the Gudmundsen Sandhills Laboratory Open House. I grew up a country boy in Texas, and any day I get to spend in rangeland is a good day to me.

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Vc Council, John Owens Jan 2004

Vc Council, John Owens

John Owens: Speeches and Appearances

No abstract provided.

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Nebraska College Of Technical Agriculture Budget Hearing, John Owens Jan 2004

Nebraska College Of Technical Agriculture Budget Hearing, John Owens

John Owens: Speeches and Appearances

Good afternoon Senator Wehrbein and members of the Appropriations Committee. I am John Owens, and I am University of Nebraska Vice President for Agriculture and Natural Resources, and Harlan Vice Chancellor of the Institute of Agriculture and Natural Resources at the University of Nebraska- Lincoln. I am here to speak with you about the impact of further budget cuts to the Nebraska College of Technical Agriculture - NCTA - at Curtis, Nebraska.

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Does Presence Of Permanent Fresh Water Affect Recruitment In Prairie-Nesting Dabbling Ducks?, Gary Krapu, Pamela Pietz, David Brandt, Robert Cox Jr. Jan 2004

Does Presence Of Permanent Fresh Water Affect Recruitment In Prairie-Nesting Dabbling Ducks?, Gary Krapu, Pamela Pietz, David Brandt, Robert Cox Jr.

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

In the Prairie Pothole Region (PPR) of North Dakota, USA, American mink (Mustela vison) are a major predator of ducklings. Mink populations plummet during severe droughts, but some mink survive where permanent fresh water is available. In 1992–1993, we evaluated whether development of a permanent water body, the 125- km McClusky Canal (MC), had affected survival of gadwall (Anas strepera) and mallard (A. platyrhynchos) broods and ducklings in surrounding wetland complexes. Twelve of 25 radiomarked gadwall and mallard hens experienced total brood loss, and 148 of 199 radiomarked ducklings from 58 broods died by …

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Hepatocellular Carcinoma In The Woodchuck Model Of Hepatitis B Virus Infection, Bud C. Tennant, Ilia A. Toshkov, Simon F. Peek, James R. Jacob, Stephan Menne, William E. Hornbuckle, Raymond D. Schinazi, Brent E. Korba, Paul J. Cote, John L. Gerin Jan 2004

Hepatocellular Carcinoma In The Woodchuck Model Of Hepatitis B Virus Infection, Bud C. Tennant, Ilia A. Toshkov, Simon F. Peek, James R. Jacob, Stephan Menne, William E. Hornbuckle, Raymond D. Schinazi, Brent E. Korba, Paul J. Cote, John L. Gerin

United States Department of Veterans Affairs: Publications

The Eastern woodchuck (Marmota monax) harbors a DNA virus (Woodchuck hepatitis virus [WHV]) that is similar in structure and replicative life cycle to the human hepatitis B virus (HBV). Like HBV, WHV infects the liver and can cause acute and chronic hepatitis. Furthermore, chronic WHV infection in woodchucks usually leads to development of hepatocellular carcinoma (HCC) within the first 2–4 years of life. The woodchuck model has been important in the preclinical evaluation of safety and efficacy of the antiviral drugs now in use for treatment of HBV infection and continues to serve as an important, predictive model …

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Omtvedt Innovation Award Winners, John Owens Jan 2004

Omtvedt Innovation Award Winners, John Owens

John Owens: Speeches and Appearances

It is such a pleasure to have this opportunity this afternoon to present four Omtvedt Innovation Awards to Institute colleagues whose outstanding work is a source of tremendous pride and inspiration for us all.

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