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Full-Text Articles in Entire DC Network
Nutrition During Gilt Development And Genetic Line Affect Reproductive Rate Through Parity 1, Rodger Johnson, Philip S. Miller, Roman Moreno, Matthew W. Anderson, Jeffrey M. Perkins, Kelsey Rhynalds, Trevor J. Glidden, Donald Mcclure, Thomas Mcgargill
Nutrition During Gilt Development And Genetic Line Affect Reproductive Rate Through Parity 1, Rodger Johnson, Philip S. Miller, Roman Moreno, Matthew W. Anderson, Jeffrey M. Perkins, Kelsey Rhynalds, Trevor J. Glidden, Donald Mcclure, Thomas Mcgargill
Nebraska Swine Reports
Effects of allowing gilts ad libitum access to feed until breeding age or developing them with 25% energy restriction from 123 days of age to breeding on reproductive success through parity 1 were studied with a total of 639 gilts of two lines that differ in lean growth and reproduction. Gilts of the two lines had common sires, an industry maternal line, but dams were from different populations. One line of gilts, LW x LR, represented standard industry Large White x Landrace cross females. The other gilts, L45X, were daughters of Nebraska selection Line 45 that has been selected 27 …
Post Weaning Management Of Heifer Calves Impacts Average Daily Gain And Feed Efficiency As Pregnant Heifers, D. M. Larson, Tonya L. Meyer, L. A. Stalker, Richard N. Funston
Post Weaning Management Of Heifer Calves Impacts Average Daily Gain And Feed Efficiency As Pregnant Heifers, D. M. Larson, Tonya L. Meyer, L. A. Stalker, Richard N. Funston
West Central Research and Extension Center, North Platte
Three experiments evaluated replacement heifer development systems and subsequent effects on gain and efficiency of pregnant heifers. In Exp. 1 and 2, were developed grazing corn residue (CR; 422 ± 5 kg) or fed in a dry lot (DL; 446 ± 5 kg) prior to breeding. In Exp. 1, a subset of pregnant heifers (n = 40) were individually fed a diet composed of 90% grass hay (11.7 % CP; DM basis) and 10% of a wet distillers grains plus solubles/straw mixture (21.8 % CP; DM basis) during late gestation. In Exp. 2, 55 pregnant …
Estrous Synchronization Increases Early Calving Frequency, Which Enhances Steer Progeny Value, D. M. Larson, Richard N. Funston
Estrous Synchronization Increases Early Calving Frequency, Which Enhances Steer Progeny Value, D. M. Larson, Richard N. Funston
West Central Research and Extension Center, North Platte
Calving records collected between 2000 and 2008 at the Gudmundsen Sandhills Laboratory, Whitman, NE, were used to determine the effect of estrous synchronization on calving distribution and the impact of time of calving on carcass characteristics. Calves born between 2000 and 2006 resulted from non-synchronized 60 d breeding seasons between 1999 and 2005 (n = 2075). Calves born in 2007 and 2008 resulted from synchronized 45 d breeding seasons in 2006 and 2007 (n = 521). Estrus was synchronized with a single injection of prostaglandin F2α administered 108 h after bulls were turned in with cows. Cow …
The Effects Of Corn Coproduct Supplementation On Primiparous Cow Reproduction And Calf Performance, D. M. Larson, R. N. Funston
The Effects Of Corn Coproduct Supplementation On Primiparous Cow Reproduction And Calf Performance, D. M. Larson, R. N. Funston
West Central Research and Extension Center, North Platte
An experiment was replicated over 2 yr to determine the effect of additional RUP and dietary fat from dried distillers grains plus solubles (DDGS; n = 2) or wet corn gluten feed (WCGF; n = 2) before breeding on primiparous cow reproduction and calf production. Over 2 yr, 134 postpartum, primiparous cows (429 ± 5 kg initial BW) were fed 1 of 2 isocaloric, approximately isonitrogenous diets in 1 pen/yr (n = 4) providing varying levels of RUP and dietary fat. Treatments were initiated 21 (yr 1) and 60 d (yr 2) postpartum and continued for 56 (yr 1) or …
A Comparison Of Melengestrol Acetate Fed At Two Dose Levels To Feedlot Heifers, G. E. Sides, J. T. Vasconcelos, R. C. Borg, O. A. Turgeon, W. C. Koers, M. S. Davis, K. Vander Pol, D. J. Weigel, C. M. Tucker
A Comparison Of Melengestrol Acetate Fed At Two Dose Levels To Feedlot Heifers, G. E. Sides, J. T. Vasconcelos, R. C. Borg, O. A. Turgeon, W. C. Koers, M. S. Davis, K. Vander Pol, D. J. Weigel, C. M. Tucker
Panhandle Research and Extension Center
A randomized complete block design was used to compare the effects of feeding melengestrol acetate (MGA) at 0.4 (0.4M) and 0.5 (0.5M) mg/d per head on feedlot performance, estrus activity, and carcass characteristics of commercial beef heifers (n = 1,418; 10 pens/ treatment). Within 48 h of arrival at the research site, heifers were assigned to treatment, processed according to feedlot protocol, and administered an abortifacient. After adaptation to a 95% concentrate diet, MGA was supplied at either 0.4 or 0.5 mg/head daily. Estrus activity was monitored twice daily and summarized as a count of heifers showing estrus within a …
Growing Rate Of Gain On Subsequent Feedlot Performance, Meat, And Carcass Quality Of Beef Steers, B. A. Loken, R. J. Maddock, M. M. Stamm, C. S. Schauer, Ivan G. Rush, S. Quinn, G. P. Lardy
Growing Rate Of Gain On Subsequent Feedlot Performance, Meat, And Carcass Quality Of Beef Steers, B. A. Loken, R. J. Maddock, M. M. Stamm, C. S. Schauer, Ivan G. Rush, S. Quinn, G. P. Lardy
Panhandle Research and Extension Center
Eighty Angus and Angus × Simmental steer calves were used in a completely random design to determine the effect of rate of BW gain during the backgrounding period on subsequent feedlot performance, carcass characteristics, Warner-Bratzler shear force (WBSF), and sensory analysis. Animals were stratified by BW and allotted randomly to 1 of 10 pens (5 pens/treatment). Dietary treatments were formulated for an ADG of 0.91 kg/d [low BW gain (LG), 1.06 Mcal of NEg/kg] diets and 1.25 kg/d [high BW gain (HG), 1.19 Mcal of NEg/kg]. Steers were fed 70 d during the growing period. The …
Rapid Gains In Yield And Adoption Of New Maize Varieties For Complex Hillside Environments Through Farmer Participation. Ii. Scaling-Up The Adoption Through Community-Based Seed Production (Cbsp), T. P. Tiwari, G. Ortiz-Ferrara, Carlos A. Urrea, R. B. Katuwal, K. B. Koirala, R. C. Prasad, D. B. Gurung, D. Sharma, B. Hamal, B. Bhandari, M. Thapa
Rapid Gains In Yield And Adoption Of New Maize Varieties For Complex Hillside Environments Through Farmer Participation. Ii. Scaling-Up The Adoption Through Community-Based Seed Production (Cbsp), T. P. Tiwari, G. Ortiz-Ferrara, Carlos A. Urrea, R. B. Katuwal, K. B. Koirala, R. C. Prasad, D. B. Gurung, D. Sharma, B. Hamal, B. Bhandari, M. Thapa
Panhandle Research and Extension Center
Participatory varietal selection (PVS) led to the identification of Population-22 and its later release as Manakamana-3. Subsequently further mother–baby trials tested five unreleased open-pollinated varieties (OPVs), ZM-621, Shitala, Population-45, Hill Pool White, and Hill Pool Yellow to compare them with Manakamana-3. Farmers again preferred Manakamana-3 as well as ZM-621 for their stable, higher grain yield, and for other traits such as stay-green, non-lodging, large white grains, and tolerance to foliar diseases. However, Manakamana- 3 and ZM-621 both had late maturity, open husks and dented grain. Both were tested with farmers on-farm coordinated farmers field trials (CFFTs) and had not been …
Draft U.S. Pacific Marine Mammal Stock Assessments: 2009, James V. Carretta, Karin A. Forney, Mark S. Lowry, Jay Barlow, Jason Baker, Dave Johnston, Brad Hanson, Robert L. Brownell Jr., Jooke Robbins, David K. Mattila, Katherine Ralls, Marcia M. Muto, Deanna Lynch, Lilian Carswell
Draft U.S. Pacific Marine Mammal Stock Assessments: 2009, James V. Carretta, Karin A. Forney, Mark S. Lowry, Jay Barlow, Jason Baker, Dave Johnston, Brad Hanson, Robert L. Brownell Jr., Jooke Robbins, David K. Mattila, Katherine Ralls, Marcia M. Muto, Deanna Lynch, Lilian Carswell
United States Department of Commerce: Staff Publications
Under the 1994 amendments to the Marine Mammal Protection Act (MMPA), the National Marine Fisheries Service (NMFS) and the U.S. Fish and Wildlife Service (USFWS) are required to publish Stock Assessment Reports for all stocks of marine mammals within U.S. waters, to review new information every year for strategic stocks and every three years for non-strategic stocks, and to update the stock assessment reports when significant new information becomes available. This report presents stock assessments for 13 Pacific marine mammal stocks under NMFS jurisdiction, including 8 “strategic” stocks and 5 “non-strategic” stocks (see summary table). A new stock assessment for …
Crop Effects On Closed System Element Cycling For Human Life Support In Space, C. L. Mackowiak, P. R. Grossl, R. M. Wheeler
Crop Effects On Closed System Element Cycling For Human Life Support In Space, C. L. Mackowiak, P. R. Grossl, R. M. Wheeler
United States National Aeronautics and Space Administration: Publications
Nutrient recycling in a space-based Bioregenerative Life Support System (BLSS) will require an understanding of nutrient dosage effects on crop production, plant tissue partitioning, and geochemical fates within crop systems. Sodium (Na+), fluoride (F−), and iodide (I−) are found in human waste streams. These elements were examined using crops in hydroponic systems. Lettuce, radish, spinach, and beet were used to study Na+ uptake and tolerance. Spinach, lettuce, and radish growth were inhibited at 8.0 × 10−2 M Na+ compared to the control. Beet growth improved at 2.0 and 4.0 × 10 …
Regional Differences In The Spatial And Temporal Heterogeneity Of Oceanographic Habitat Used By Steller Sea Lions, Michelle E. Lander, Thomas R. Loughlin, Miles G. Logsdon, Glenn R. Vanblaricom, Brian S. Fadely, Lowell W. Fritz
Regional Differences In The Spatial And Temporal Heterogeneity Of Oceanographic Habitat Used By Steller Sea Lions, Michelle E. Lander, Thomas R. Loughlin, Miles G. Logsdon, Glenn R. Vanblaricom, Brian S. Fadely, Lowell W. Fritz
United States Department of Commerce: Staff Publications
Over the past three decades, the decline and altered spatial distribution of the western stock of Steller sea lions (Eumetopias jubatus) in Alaska have been attributed to changes in the distribution or abundance of their prey due to the cumulative effects of fisheries and environmental perturbations. During this period, dietary prey occurrence and diet diversity were related to population decline within metapopulation regions of the western stock of Steller sea lions, suggesting that environmental conditions may be variable among regions. The objective of this study, therefore, was to examine regional differences in the spatial and temporal heterogeneity of …
Reduced Genomic Potential For Secreted Plant Cell-Wall-Degrading Enzymes In The Ectomycorrhizal Fungus Amanita Bisporigera, Based On The Secretome Of Trichoderma Reesei, Subashini Nagendran, Heather E. Hallen-Adams, Janet M. Paper, Nighat Aslam, Jonathan D. Walton
Reduced Genomic Potential For Secreted Plant Cell-Wall-Degrading Enzymes In The Ectomycorrhizal Fungus Amanita Bisporigera, Based On The Secretome Of Trichoderma Reesei, Subashini Nagendran, Heather E. Hallen-Adams, Janet M. Paper, Nighat Aslam, Jonathan D. Walton
Heather Hallen-Adams Publications
Based on the analysis of its genome sequence, the ectomycorrhizal (ECM) basidiomycetous fungus Laccaria bicolor was shown to be lacking many of the major classes of secreted enzymes that depolymerize plant cell wall polysaccharides. To test whether this is also a feature of other ECM fungi, we searched a survey genome database of Amanita bisporigera with the proteins found in the secretome of Trichoderma reesei (syn. Hypocrea jecorina), a biochemically well-characterized industrial fungus. Additional proteins were also used as queries to compensate for major groups of cell-wall-degrading enzymes lacking in the secretome of T. reesei and to substantiate conclusions …
Future Of Water For Food: Proceedings Of The Future Of Water For Food Conference Held At The University Of Nebraska–Lincoln, May 3-5, 2009, University Of Nebraska–Lincoln Office Of Research And Economic Development
Future Of Water For Food: Proceedings Of The Future Of Water For Food Conference Held At The University Of Nebraska–Lincoln, May 3-5, 2009, University Of Nebraska–Lincoln Office Of Research And Economic Development
Office of Research and Economic Development: Publications
“Water is key. It’s a critical issue. In many cases, it’s a critical limitation. And we come together probably in some cases with different perspectives, but I think we can all agree that it’s a critical challenge, one that we must take on,” said Jeff Raikes, chief executive officer of the Bill & Melinda Gates Foundation in his keynote address at the Future of Water for Food conference.
Hosted by the University of Nebraska and the Bill & Melinda Gates Foundation, the conference was held at the University of Nebraska–Lincoln, May 3-5, 2009. The conference brought together more than 230 …
2008 Major Sponsored Programs And Faculty Awards For Research And Creative Activity, Office Of Research, University Of Nebraska–Lincoln
2008 Major Sponsored Programs And Faculty Awards For Research And Creative Activity, Office Of Research, University Of Nebraska–Lincoln
Office of Research and Economic Development: Publications
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Resistance To Therapies For Infection By Plasmodium Vivax, J. Kevin Baird
Resistance To Therapies For Infection By Plasmodium Vivax, J. Kevin Baird
United States Public Health Resources
The scope and depth of this review reflect the complexity of therapy for malaria in general and of Plasmodium vivax in particular. Even for malariologists steeped in an understanding of the treatment of acute, uncomplicated malaria caused by Plasmodium falciparum, P. vivax challenges. The tendency to fold the two species together into a single conceptual framework, and they indeed share some common ground, leads to errors in both strategic reasoning and practice with therapies. These two species are biologically and clinically distinct in fundamentally important ways. This review attempts to draw a distinction with P. vivax in the broad context …
Extensive Heifer Development Systems, Richard N. Funston, Jeremy Martin, Andy Roberts
Extensive Heifer Development Systems, Richard N. Funston, Jeremy Martin, Andy Roberts
Range Beef Cow Symposium
Studies in numerous species provide evidence that diet during development can partially control physiological changes necessary for puberty (Frisch, 1984). Energy balance or plane of nutrition influences reproductive performance in heifers and cows (Butler and Smith, 1989; Randel, 1990; Robinson, 1990; Short and Adams, 1988; Swanson, 1989). Numerous studies have reported inverse correlations between postweaning growth rate and age at puberty (Arije and Wiltbank, 1971; Ferrell, 1982; Short and Bellows, 1971; Wiltbank et al., 1966, 1969, 1985) and pregnancy rates in heifers were shown to be dependent upon the number displaying estrus prior to or early in the breeding season …
Common $Ense Heifer Management, Patsy Houghton
Common $Ense Heifer Management, Patsy Houghton
Range Beef Cow Symposium
The replacement heifer is a mixed blessing for cow-calf operators. On one hand, she represents the future profitability and genetic improvement of the cow herd; thus her selection and development are of paramount importance to the continued success of any cow herd. On the other hand, the replacement heifer is an inconvenience at best. She is essentially non-productive for the first two-and-a-half years of her life; thus she places a significant drain on a rancher’s cash flow, making her easy prey for mismanagement. Nevertheless, proper growth and development of the replacement female from birth until she produces her first calf …
Impact Of Method Of Heifer Development And Post-Ai Management On Reproductive Efficiency, George Perry, Julie Walker, Cody Wright, Ken Olson
Impact Of Method Of Heifer Development And Post-Ai Management On Reproductive Efficiency, George Perry, Julie Walker, Cody Wright, Ken Olson
Range Beef Cow Symposium
An important part of any production system is the reproductive performance and costs associated with developing replacement heifers. The cost of developing replacement heifers has a tremendous impact on the profitability and sustainability of cow-calf operations, and reproductive failure costs the U.S. beef and dairy industries approximately $1 billion annually (Bellows et al., 2002). Heifers need to calve by 24 months of age to achieve maximum life-time productivity (Patterson et al., 1992), and heifers that lose a pregnancy or conceive late in the breeding season are likely to not have enough time to rebreed during a defined breeding season. In …
Profitable Cow And Heifer Pregnancy Rates, Jack C. Whittier
Profitable Cow And Heifer Pregnancy Rates, Jack C. Whittier
Range Beef Cow Symposium
Wow! What a challenging topic. Why is it challenging? Because there is not one right answer; nor is the question easy to define or analyze. However, there are some underlying principles that I believe apply in most situations. I will spend most of my time on those principles with the hope that you as a cattle manager can use these principles to make good decisions.
Impacts Of Calf Nutritional Management On Quality Grade, Scott Lake
Impacts Of Calf Nutritional Management On Quality Grade, Scott Lake
Range Beef Cow Symposium
Why is quality important? An enormous amount of research and money have been invested in determining the impacts of just about every management practice on the effects of marbling. Marketing and management practices have been developed around the choice/select spread. But the question begs to be asked, “Is marbling important?” Regardless of the choice/select spread or any other premiums received due to carcass quality, the answer to that question should be a resounding “YES”, for no other reason than the importance of a quality eating experience from consumers. The 2005 National Quality Beef Audit reports that the #1 concern of …
U.S. Beef Demand Drivers And Enhancement Opportunities: A Research Summary, James R. Mintert, Glynn T. Tonsor, Ted C. Schroeder
U.S. Beef Demand Drivers And Enhancement Opportunities: A Research Summary, James R. Mintert, Glynn T. Tonsor, Ted C. Schroeder
Range Beef Cow Symposium
Large shifts in domestic beef demand have had substantial impacts on the beef industry. Before the late 1970s, growth in the U.S. economy and rising consumer incomes contributed to beef demand increasing for a sustained period. In response to growing product demand, the beef industry increased in size. However, starting about 1980, domestic retail beef demand weakened and subsequently declined every year through 1998. The long-run decline in retail beef demand contributed to a reduction in cattle industry size, particularly in relation to competing meat sectors such as poultry and pork. In 1999, following nearly 20 consecutive years of decline, …
Rumen Physiology For The Rancher, Ivan G. Rush
Rumen Physiology For The Rancher, Ivan G. Rush
Range Beef Cow Symposium
The ruminant animal has two unique features – it chews its cud and has four distinct compartments in the stomach. More importantly the ruminant can convert forages that are comprised by large quantities of cellulose, that is poorly digestible by non-ruminants, into high quality protein (muscle) that provides excellent eating experiences and nutrients for humans. Rumen Physiology is the study of the mechanical, physical and biochemical function of the rumen. When I first enrolled in an animal nutrition course I felt this area was unnecessary in order to feed cattle. All I wanted to learn was does the cow need …
Two Best And Two Worst Decisions, Kory Bierle
Two Best And Two Worst Decisions, Kory Bierle
Range Beef Cow Symposium
My name is Kory Bierle and I am from a family ranch just east of Midland, South Dakota, on the Bad River. The name of our ranch is the Madsen Ranch. We use that name because it was my mother’s family that settled and started the place. My great-great-grandfather showed my great-grandfather where a good place for a ranch would be, and we’ve been there ever since. My house is just a few yards from where the original log house was. The gal that talked to me about participating in the Range Beef Cow Symposium this year said that, from …
Bovine Respiratory Disease & Diagnostic Veterinary Medicine (Managing Respiratory Diseases In The Herd), Donald Montgomery
Bovine Respiratory Disease & Diagnostic Veterinary Medicine (Managing Respiratory Diseases In The Herd), Donald Montgomery
Range Beef Cow Symposium
Year in and year out, diseases of the respiratory system are a major cause of illness and death in cattle from 6 weeks to two years of age. Sadly, this is as true today as it was 30 years ago despite development of new and improved vaccines, new broad spectrum antibiotics, and increased fundamental knowledge as to the cause of disease. WHY? I don‟t have the answer and I doubt if anyone does. As a pathologist, I often see firsthand the devastating effects that bacteria can have in the lungs of cattle that die from respiratory disease complex or shipping …
Do Fence Me In: Cattle Enlisted In The Great Basin To Reverse The Cheatgrass/Wildfire Cycle, Elise Lequire
Do Fence Me In: Cattle Enlisted In The Great Basin To Reverse The Cheatgrass/Wildfire Cycle, Elise Lequire
Joint Fire Science Program Briefs (2007-2012)
Cheatgrass and cattle have co-existed in the Great Basin since the late 19th century, when both were introduced by settlers of the western territories. Unchecked grazing of the sagebrush-steppe community decimated the native perennial grasses in some areas and gave cheatgrass, a nonnative annual, permanent inroads into the ecosystem. Cheatgrass is generally palatable and nutritious for cattle in spring, but dries quickly in the hot, dry summers typical of the Great Basin, becoming a flashy fuel that carries fire quickly. The invasion has drastically shortened the fire return interval and led to increasingly intense and fast spreading wildfi res, which …
Winter Grazing System And Supplementation During Late Gestation Influence Performance Of Beef Cows And Steer Progeny, Daniel Larson, J. L. Martin, Don C. Adams, Richard N. Funston
Winter Grazing System And Supplementation During Late Gestation Influence Performance Of Beef Cows And Steer Progeny, Daniel Larson, J. L. Martin, Don C. Adams, Richard N. Funston
Department of Animal Science: Faculty Publications
A 2 × 2 factorial study evaluated effects of cow wintering system and last trimester CP supplementation on performance of beef cows and steer progeny over a 3-yr period. Pregnant composite cows (Red Angus × Simmental) grazed winter range (WR; n = 4/yr) or corn residue (CR; n = 4/yr) during winter and within grazing treatment received 0.45 kg/d (DM) 28% CP cubes (PS; n = 4/yr) or no supplement (NS; n = 4/yr). Offspring steer calves entered the feedlot 14 d postweaning and were slaughtered 222 d later. Precalving BW was greater (P = 0.02) for PS than NS …
Comparison Of Dry Distillers Or Modified Wet Distillers Grains Plus Solubles In Wet Or Dry Forage Based Diets, Mallorie Willken, Terry L. Mader, Galen E. Erickson, Leslie J. Johnson
Comparison Of Dry Distillers Or Modified Wet Distillers Grains Plus Solubles In Wet Or Dry Forage Based Diets, Mallorie Willken, Terry L. Mader, Galen E. Erickson, Leslie J. Johnson
Nebraska Beef Cattle Reports
Modified wet distillers grains plus solubles (MDGS) or dry distiller grains plus solubles (DDGS) in combination with wet or dry forages were fed to growing steer calves (n =192). They were fed one of four treatments in a 2 x 2 factorial arrangement with factors as wet or dry forage and MDGS or DDGS for 105 days. Gain and feed-to-gain ratio (F:G) of steers fed MDGS were similar to those fed DDGS. Feeding wet forage significantly improved average daily gain (ADG) and F:G compared to feeding dry forage, which likely reflects forage quality in this study.
Natural History Note No Trade-Off Between Seed Size And Number In The Valley Oak Quercus Lobata, Walter D. Koenig, Johannes M.H. Knops, William J. Carmen, Richard D. Sage
Natural History Note No Trade-Off Between Seed Size And Number In The Valley Oak Quercus Lobata, Walter D. Koenig, Johannes M.H. Knops, William J. Carmen, Richard D. Sage
School of Biological Sciences: Faculty Publications
We examined the relationship between acorn mass and number in valley oaks (Quercus lobata) over 4 years in central coastal California. Despite considerable variation in acorn size among both trees and years, trees produced acorns of the same size relative to other trees in different years. Across years, the relationship between acorn mass and acorn crop size was generally positive, even after controlling for environmental conditions and differences in individual tree size and quality. Life-history trade-offs in valley oaks are primarily between current and future reproduction and indirectly between concurrent growth and reproduction, not between seed size and …
Role Of Vapbc Toxin–Antitoxin Loci In The Thermal Stress Response Of Sulfolobus Solfataricus, Charlotte R. Cooper, Amanda J. Daugherty, Sabrina Tachdjian, Paul H. Blum, Robert M. Kelly
Role Of Vapbc Toxin–Antitoxin Loci In The Thermal Stress Response Of Sulfolobus Solfataricus, Charlotte R. Cooper, Amanda J. Daugherty, Sabrina Tachdjian, Paul H. Blum, Robert M. Kelly
School of Biological Sciences: Faculty Publications
TA (toxin–antitoxin) loci are ubiquitous in prokaryotic microorganisms, including archaea, yet
their physiological function is largely unknown. For example, preliminary reports have suggested
that TA loci are microbial stress-response elements, although it was recently shown that knocking
out all known chromosomally located TA loci in Escherichia coli did not have an impact on
survival under certain types of stress. The hyperthermophilic crenarchaeon Sulfolobus solfataricus
encodes at least 26 vapBC (where vap is virulence-associated protein) family TA loci in its
genome. VapCs are PIN (PilT N-terminus) domain proteins with putative ribonuclease activity,
while VapBs are proteolytically labile proteins, which purportedly function …
The Amphipod Orchomenella Pinguis — A Potential Bioindicator For Contamination In The Arctic, Lis Bach, Valery E. Forbes, Ingela Dahllöf
The Amphipod Orchomenella Pinguis — A Potential Bioindicator For Contamination In The Arctic, Lis Bach, Valery E. Forbes, Ingela Dahllöf
Valery Forbes Publications
Indigenous organisms can be used as bioindicators for effects of contaminants, but no such bioindicator has been established for Arctic areas. Orchomenella pinguis is a benthic amphipod, ubiquitous in the Arctic and can be found in high numbers. We collected O. pinguis at sites with different contamination levels. Population characteristics (body length distribution, average dry weight and amphipod organic content) were related to sediment contaminant concentrations, in order to identify suitable endpoints for using this species as a bioindicator. We show that O. pinguis was prevalent in both clean and contaminated areas, easy to sample and that its population characteristics …
Cadmium-Mediated Rescue From Er-Associated Degradation Induces Expression Of Its Exporter, David J. Adle, Wenzhong Wel, Nathan Smith, Joshua J. Bles, Jaekwon Lee
Cadmium-Mediated Rescue From Er-Associated Degradation Induces Expression Of Its Exporter, David J. Adle, Wenzhong Wel, Nathan Smith, Joshua J. Bles, Jaekwon Lee
Department of Biochemistry: Faculty Publications
Cadmium is a highly toxic environmental contaminant that has been implicated in various disorders. A major mechanism for cadmium detoxification in the yeast Saccharomyces cerevisiae relies on extrusion via Pca1, a P-type ATPase. While an N-terminal degron targets Pca1 for degradation before its secretion to the plasma membrane, cadmium in the growth media rapidly upregulates Pca1 by preventing its turnover. Here we show that the endoplasmic reticulum-associated degradation (ERAD) system, known for its role in quality control of secretory proteins, is unexpectedly responsible for the regulation of Pca1 expression by cadmium. Direct cadmium sensing at the ER by a degron …