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History Of The Coal Tax, Thomas E. Towe Aug 2020

History Of The Coal Tax, Thomas E. Towe

Public Land & Resources Law Review

No abstract provided.


The Wild River Bill: House Bill 133, Harrison Fagg Aug 2020

The Wild River Bill: House Bill 133, Harrison Fagg

Public Land & Resources Law Review

No abstract provided.


Stream Access Remembrance, Ron Waterman Aug 2020

Stream Access Remembrance, Ron Waterman

Public Land & Resources Law Review

No abstract provided.


Implementation Of Montana's Strip Mine Legislation, Leo Berry Aug 2020

Implementation Of Montana's Strip Mine Legislation, Leo Berry

Public Land & Resources Law Review

No abstract provided.


The Water Use Act, Gary Wicks Aug 2020

The Water Use Act, Gary Wicks

Public Land & Resources Law Review

No abstract provided.


A Little History And A Few Of Its Heroes, Daniel Kemmis Aug 2020

A Little History And A Few Of Its Heroes, Daniel Kemmis

Public Land & Resources Law Review

No abstract provided.


A Retrospective: The Golden Years, Peter M. Meloy Aug 2020

A Retrospective: The Golden Years, Peter M. Meloy

Public Land & Resources Law Review

No abstract provided.


The Hard Rock Mining Bill: House Bill 243, Harrison Fagg Aug 2020

The Hard Rock Mining Bill: House Bill 243, Harrison Fagg

Public Land & Resources Law Review

No abstract provided.


The Senate Democratic Caucus Of 1975, Thomas E. Towe Aug 2020

The Senate Democratic Caucus Of 1975, Thomas E. Towe

Public Land & Resources Law Review

No abstract provided.


An Epic Depate, Greg Jergeson Aug 2020

An Epic Depate, Greg Jergeson

Public Land & Resources Law Review

No abstract provided.


How House Bill 666 And Grass Roots Democracy Won Subdivision Reform For Montana, John Vincent Aug 2020

How House Bill 666 And Grass Roots Democracy Won Subdivision Reform For Montana, John Vincent

Public Land & Resources Law Review

No abstract provided.


The Montana Environmental Information Center, Robin Nichols Aug 2020

The Montana Environmental Information Center, Robin Nichols

Public Land & Resources Law Review

No abstract provided.


The 1972 Montana State Constitution Declaration Of Rights And The Opportunities On The Bumpy Road Ahead, Rick Applegate Aug 2020

The 1972 Montana State Constitution Declaration Of Rights And The Opportunities On The Bumpy Road Ahead, Rick Applegate

Public Land & Resources Law Review

No abstract provided.


My Glory Days: How I Came To Be In The Right Place At The Right Time., Mae Nan Ellingson Aug 2020

My Glory Days: How I Came To Be In The Right Place At The Right Time., Mae Nan Ellingson

Public Land & Resources Law Review

No abstract provided.


The Writing And Ratification Of The 1972 Montana Constitution, Bob Campbell Aug 2020

The Writing And Ratification Of The 1972 Montana Constitution, Bob Campbell

Public Land & Resources Law Review

No abstract provided.


Alice Creek, Dolores Colburg Aug 2020

Alice Creek, Dolores Colburg

Public Land & Resources Law Review

No abstract provided.


Montana (1959 – 1989) Political Evolution — Political Revolution, Ted Schwinden Aug 2020

Montana (1959 – 1989) Political Evolution — Political Revolution, Ted Schwinden

Public Land & Resources Law Review

No abstract provided.


Author Biographies Aug 2020

Author Biographies

Public Land & Resources Law Review

No abstract provided.


Table Of Contents Aug 2020

Table Of Contents

Public Land & Resources Law Review

No abstract provided.


Letter From The Editor Aug 2020

Letter From The Editor

Public Land & Resources Law Review

No abstract provided.


Plrlr Editors And Staff Aug 2020

Plrlr Editors And Staff

Public Land & Resources Law Review

No abstract provided.


Montana Kaimin, August 19, 2020, Students Of The University Of Montana, Missoula Aug 2020

Montana Kaimin, August 19, 2020, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.


Prion Protein Lowering Is A Disease-Modifying Therapy Across Prion Disease Stages, Strains And Endpoints, Eric Vallabh Minikel, Hien T. Zhao, Jason Le, Jill O'Moore, Rose Pitstick, Samantha Graffam, George A. Carlson, Michael P. Kavanaugh Aug 2020

Prion Protein Lowering Is A Disease-Modifying Therapy Across Prion Disease Stages, Strains And Endpoints, Eric Vallabh Minikel, Hien T. Zhao, Jason Le, Jill O'Moore, Rose Pitstick, Samantha Graffam, George A. Carlson, Michael P. Kavanaugh

Biomedical and Pharmaceutical Sciences Faculty Publications

Lowering of prion protein (PrP) expression in the brain is a genetically validated therapeutic hypothesis in prion disease. We recently showed that antisense oligonucleotide (ASO)-mediated PrP suppression extends survival and delays disease onset in intracerebrally prion-infected mice in both prophylactic and delayed dosing paradigms. Here, we examine the efficacy of this therapeutic approach across diverse paradigms, varying the dose and dosing regimen, prion strain, treatment timepoint, and examining symptomatic, survival, and biomarker readouts. We recapitulate our previous findings with additional PrP-targeting ASOs, and demonstrate therapeutic benefit against four additional prion strains. We demonstrate that


August 2020 News Releases, University Of Montana--Missoula. Office Of University Relations Aug 2020

August 2020 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.


July 2020 News Releases, University Of Montana--Missoula. Office Of University Relations Jul 2020

July 2020 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.


Reduced Expression Of The Pp2a Methylesterase, Pme-1, Or The Pp2a Methyltransferase, Lcmt-1, Alters Sensitivity To Beta-Amyloid-Induced Cognitive And Electrophysiological Impairments In Mice, Agnieszka Staniszewski, Hong Zhang, Kesava Asam, Rose Pitstick, Michael P. Kavanaugh, Ottavio Arancio, Russell E. Nicholls Jun 2020

Reduced Expression Of The Pp2a Methylesterase, Pme-1, Or The Pp2a Methyltransferase, Lcmt-1, Alters Sensitivity To Beta-Amyloid-Induced Cognitive And Electrophysiological Impairments In Mice, Agnieszka Staniszewski, Hong Zhang, Kesava Asam, Rose Pitstick, Michael P. Kavanaugh, Ottavio Arancio, Russell E. Nicholls

Biomedical and Pharmaceutical Sciences Faculty Publications

Beta-amyloid (Ab) is thought to play a critical role in Alzheimer’s disease (AD), and application of soluble oligomeric forms of Ab produces AD-like impairments in cognition and synaptic plasticity in experimental systems. We found previously that transgenic overexpression of the PP2A methylesterase, PME-1, or the PP2A methyltransferase, LCMT-1, altered the sensitivity of mice to Ab-induced impairments, suggesting that PME-1 inhibition may be an effective approach for preventing or treating these impairments. To explore this possibility, we examined the behavioral and electrophysiological effects of acutely applied synthetic Ab oligomers in male and female mice heterozygous for either a PME-1 KO or …


Providing Opportunities To Develop Prospective Teachers’ Pedagogical Content Knowledge, Aina Appova, Cynthia E. Taylor Jun 2020

Providing Opportunities To Develop Prospective Teachers’ Pedagogical Content Knowledge, Aina Appova, Cynthia E. Taylor

The Mathematics Enthusiast

One responsibility of mathematics teacher educators is to provide opportunities for prospective teachers to develop the necessary knowledge to be highly qualified professionals and effective mathematics teachers. Hill, Ball, and Schilling (2008) delineated two major knowledge domains required for mathematics teachers to be effective: subject matter knowledge and pedagogical content knowledge. In this article, based on literature review, we explore specific recommendations for mathematics teacher educators, including mathematicians and novice mathematics teacher educators, on different ways to incorporate lesson ideas into mathematics content courses to help provide opportunities for grades K-8 (age 5-14) prospective teachers’ development of pedagogical content knowledge. …


Biob 170n.01d: Principles Of Biological Diversity, Gregory D. Peters Jun 2020

Biob 170n.01d: Principles Of Biological Diversity, Gregory D. Peters

University of Montana Course Syllabi

No abstract provided.


Biob 161.50b: Principles Of Living Systems Lab, Laurie A. Minns Jun 2020

Biob 161.50b: Principles Of Living Systems Lab, Laurie A. Minns

University of Montana Course Syllabi

No abstract provided.


Biob 171n.01d: Principles Of Biological Diversity Lab, Gregory D. Peters Jun 2020

Biob 171n.01d: Principles Of Biological Diversity Lab, Gregory D. Peters

University of Montana Course Syllabi

No abstract provided.