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The Neuroprotective Effects Of Estradiol And Genistein In Zebra Finch Cerebellum, Renee E. Breaux

Honors Theses

The estradiol (E2) synthetic pathway converts testosterone to E2 via aromatase (AROM) and plays an important role in neuroplasticity. However, exogenous E2 increases cancer risk and interferes with gonadal function. Phytoestrogens, plant-based estrogens, may provide neuroprotection without negative E2 effects. Genistein (GEN), a soy phytoestrogen, preferentially binds to estrogen receptor beta (ER β), which is expressed at a relatively higher concentration than ER α in the cerebellum (CB). The songbird CB is an ideal model for steroid-mediated plasticity. Songbird brains are highly plastic and CB contains all steroid-synthetic enzymes. Previous studies in zebra finches (ZF) have shown that AROM and …

Evaluating The Barriers Of Entry That Small Commercial Farmers Face And The Implications Of Such Barriers On Rural Communities, Lauren C. Chandler

Honors Theses

The research proposed in this thesis will identify the barriers of entry that

small farmers face when entering the Agricultural Industry. The proposed research will also seek to discover how having these barriers in place affects rural communities. This thesis conducts a literature review of the topic, sets the context for the research to be done, and proposes a research project to further investigate the topic. The proposed research will be done through administering a survey to stakeholders, and then interviewing a small sample of those surveyed to get a comprehensive look at the effects of agribusiness on rural communities. …

Lessons From The Aisles: A Collection Of Short Stories, Drew Jones

Honors Theses

This thesis is a collection of short stories, each set in a separate aisle of Walmart. By exploring the relationships and conflicts of these characters, I hope to illustrate that life’s complexity can be shown in a place as simple and mundane as Walmart.

Comprehensive Review Of Accounting: A Case-By-Case Study, Cristina Trefry

Honors Theses

This thesis was prepared to investigate a variety of accounting scenarios to further learn and challenge student’s notion of accounting. These accounting scenarios were in the form of 11 case studies done over the course of September 2020 to April 2021. These case studies highlighted a wide variety of accounting concepts, and even challenged students to a case competition highlighted in cases 6 through 10. These case studies not only challenged students to think about accounting concepts in a different light, but also to learn more about the field they are going into through personalized cases. These personalized cases allowed …

Synthesis Of Fluorinated Ketones For Biological Evaluation At The Gaba-B Receptor, Katherine Kreusel

Honors Theses

The proper functioning of the CNS depends on the balance between excitatory and inhibitory neurotransmitters. While excitation is primarily regulated by glutamate, inhibition is regulated by γ-aminobutyric acid (GABA). When GABA binds to a GABA receptor, there is a block in nerve transmission which is important when studying pain and drug addiction. There are two types of GABA receptors that are used as drug targets: GABA-A and GABA-B. While GABA-A receptors are ionotropic and ligand-gated ion channels, GABA-B receptors are G-protein coupled receptors that are used by cells to convert extracellular signals into intracellular responses. Although many therapeutics modulate the …

Employing A Public Policy Evaluative Framework: An Analysis Of Domestic Theme Park Development, Anthony Gray Houser

Honors Theses

The intention of the thesis is to examine the relationship between the development of the Walt Disney Company’s theme parks and public policy. Using the Disneyland Resort in Anaheim, California and the Walt Disney World Resort outside of Orlando, Florida as case studies, this thesis will execute a comparative analysis to better understand the relationship between the Walt Disney Company’s theme parks and public policy. Using an evaluative framework, this thesis will provide a deeper understanding of how public policy affected the development and the current operations of these theme parks. The driving research question in this thesis is, ‘what …

Strategic Planning With Chi Alpha Christian Fellowship At The University Of Mississippi, Taylor R. Coe

Honors Theses

In this paper, I detail the strategic planning process undertaken by Chi Alpha Christian Fellowship at the University of Mississippi. I do this by first presenting information about strategic planning and about Chi Alpha as an organization. Then, I present a narrative detailing how we completed the planning process. After that, I present the results that make up the strategic plan itself. I end with an evaluation of the overall effort. Our planning process created strategies to address five strategic issues: reaching international students, lacking a unified discipleship structure, lacking a property, developing a “missions mindset” instead of a “leadership …

The Efficacy Of The Covid-19 Vaccine In Mississippi, Ilyse Miriam Levy

Honors Theses

The Efficacy of The COVID-19 Vaccine in Mississippi

(Under the direction of Dr. Xin Dang)

By tracking and analyzing fifty-three weeks of COVID-19 data, this thesis analyzes the efficacy of the COVID-19 vaccine within the State of Mississippi. Over the course of these fifty-three weeks, I have also been able to calculate the confidence intervals for vaccination efficacy and the risk reduction due to vaccination by using data regarding the correlations between deaths and vaccination status, provided to me by the Mississippi Office of Epidemiology. My analysis demonstrates that the COVID-19 vaccine is effective not only in Mississippi but also …

Characterizing The Roles Of Cannabinoid Receptor 1 & 2 In Zebrafish Behavior, Metabolism, And Seizure-Induced Activity, Kayci Kimmons

Honors Theses

Epileptic disorders like Dravet Syndrome require novel studies to determine the most ideal treatment. New research linking the endocannabinoid system (ECS) to epileptic disorders is arising, but there is still much to be discovered about the function and regulatory impact of the endocannabinoid system and its receptors in epilepsies like Dravet. In this study, knockout models of larval and adult zebrafish (Danio rerio) were used to investigate the roles of cannabinoid receptors 1 & 2 in behavior, brain mitochondrial metabolism, and seizure-induced activity following exposure to THC and CBD. Larval zebrafish which lacked cannabinoid receptor 1 exhibited increased …

Species Diversity And Growth Rates Of Overstory Vegetation Over 25 Years In Response To Physical And Chemical Properties In Long-Term Monitoring Plots At The University Of Mississippi Field Station, Mitchell Tharp

Honors Theses

Overstory vegetation for twenty-two long-term monitoring plots (LTMPs) was sampled from 1996 to 2021 to study the changes in vegetation due to natural and human disturbance. From the fall of 2020 through the fall of 2021, the overstory of the 22 LTMPs was resampled and soil samples were collected from each plot. The circumference at breast height (CBH) and species diversity were recorded and compared to previous years’ data. The objectives of this study were to: (1) document changes in the overstory species of the LTMPs, (2) measure growth rates of surviving trees, (3) survey how elevation and slope impact …

Covalent Modification Of Recombinant Protein With Reactive Thiols, Sawyer Dulaney, Bailey Taylor

Honors Theses

Many diseases cause chronic and painful inflammation in different body systems. One of the front-line drug classes to treat such inflammation is Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Despite the benefits of oral administration of NSAIDs, there are drawbacks to their long-term usage because they can cause detrimental effects on off-target systems in the body such as the liver, kidney, or the lining of the intestinal tract. An alternative to NSAIDs is the usage of hydrogels for targeted drug delivery. Hydrogels can provide drug delivery in a specific portion of the site of inflammation, thus allowing higher doses of medication to be …

Optimization Of A Fluidized Bed Reactor For The Production Of Styrene From Ethylbenzene, Gregory Espenan

Honors Theses

In order to optimize Unit 500, a styrene production plant, the Net Present Value (NPV) was used as the objective function to ensure every optimization strategy had a positive economic effect. To optimize a chemical plant, it is important to note efficiency, economics, product specifications, and production requirements. The goal of this project was to make changes to the base case of Unit 500 to minimize the cost to produce styrene for an upstream unit. PRO/II was used to simulate various points in different unit operations throughout the process. The NPV was measured after each unit operation was simulated to …

The Effects Of Crowding Agents On The Pka Of Physiologically Stable I-Motif Dna, Courtney Turner

Honors Theses

The overall goal of this thesis was to investigate the environmental conditions that induce i-Motif folding of the DNA strand DUX4L22, a cytosine-rich segment of DNA found in the human genome. Cellular conditions were simulated using sodium cacodylate buffer and multiple weights of polyethylene glycol as a crowding agent. The presence of i-motifs were confirmed by Circular Dichroism spectroscopy. I found that DUX4L22 does form i-motifs under these physiological simulations at both acidic and neutral pHs. DUX4L22 therefore shows potential for use in studies of a wide variety of biotechnological advances, such as regulatory switches in nanomachines or drug-delivery systems.

The Influence Of Culture On The Accounting Profession: An Investigation Into The Implementation Of The Oecd's Inclusive Framework On Beps In The United States And Germany, Vivian Francis

Honors Theses

This research investigates the United States and Germany’s implementation of the OECD’s Inclusive Framework on BEPS and assesses the degree to which each country’s response was influenced by its culture. The objective of this research is to present a perspective on how international accounting regulations can take cultural characteristics into consideration in order to produce their desired outcomes. For the purpose of this thesis culture is defined and quantified through the framework developed by Geert Hofstede. Furthermore, this thesis investigates the relationship between the neoliberal political paradigm and the role of culture in accounting. This research uses a combination of …

Confronting Stigma: Ethical Leadership, Influence, And The Dignity Of People Struggling With Addiction, Jacob Fennell

Honors Theses

People struggling with addiction in the United States of America deserve better treatment. The current stigma of people struggling with addiction as moral failures perpetuates a policy of drugs that sees them as criminal. This policy should be repealed and a better culture of care should be created. People struggling with addiction deserve a standard of treatment based on the core tenet of human dignity. In engaging with the history and cultural beliefs that are the foundation of this mistreatment, this same tenet of dignity must be upheld. This specifically comes into my project when exploring methods of changing these …

American Goldfinches (Spinus Tristis): Changes In Behavior During Mycoplasma Gallisepticum Infection, Hetal Shingrani

Honors Theses

Animal sickness behavior is an important component of disease ecology and is essential to understanding wildlife diseases and how and where animals allocate resources for survival. This study examines sickness behaviors, the extent of conjunctivitis, and the presence of an antibody response in relation to a Mycoplasma gallisepticum (MG) respiratory infection in American goldfinches. We conducted an experimental infection of American goldfinches and recorded behavior videos, and collected blood samples, throat swabs, eye swelling, and mass data at multiple time points throughout the experiment. An ELISA-serum assay was run after the conclusion of the study to identify the presence of …

The Design Of A Pcr-Based Assay To Detect And Isolate The Serine Palmitolytransferase Gene From Environmental Bacteria, Lana Taylor

Honors Theses

Sphingolipids are a natural class of lipids that function as structural elements of cell membranes and signaling molecules for important cellular activities such as cell growth, differentiation, apoptosis, recognition, and adhesion. These lipids can be found universally in eukaryotic cells as well as some species of bacteria, such as those found in the human gut microbiome and in the environment in soils. Though sphingolipid production is rare in bacteria, both eukaryotic and prokaryotic sphingolipid biosynthesis begin with the condensation of serine and palmitoyl CoA into 3-ketodihydrosphingosine catalyzed by the enzyme serine palmitoyltransferase (SPT). In recent years, several studies have shown …

May 3, 2022, University Of Mississippi. Faculty Senate

Meeting Minutes

Minutes for the May 3, 2022 meeting of the University of Mississippi Faculty Senate.

May 3, 2022, University Of Mississippi. Faculty Senate

Meeting Agendas

Agenda for the May 3, 2022 meeting of the University of Mississippi Faculty Senate.

Flies Don't Enter A Closed Mouth, Margaret Perez

Graduate Theses in Studio Art

From the Artist's Statement: "The work in Flies Don't Enter A Closed Mouth is both photographed and drawn, digitally printed and hand-made, flat and assembled into three-dimensional installations."

Breaking Boundaries And Making Her Way - Journey To Commencement, Lou Tyson

Journey to Commencement

Tayler Glover fosters opportunities for women in computer science.

Acquiring Knowledge To Support Those In Need - Journey To Commencement, Cameron Smith

Journey to Commencement

Erin Bowens pursues her passion and develops skills in speech-language pathology.

Match Made In Pharmacy - Journey To Commencement, Whitney Tarp

Journey to Commencement

Nason and Shelby Wise found the perfect matches in each other and the profession.

Ralph Eubanks Recognized For Reflecting Mississippi, Rebecca Lauck Cleary

University of Mississippi News

UM alumnus and visiting professor honored by Mississippi Humanities Council

Graduate Student Earns Summer Internship At Library Of Congress, Edwin B. Smith

University of Mississippi News

Roger Davis Jr. is among 42 selected for distinguished program

Journey To Commencement: Mattie Ford, Rebecca Lauck Cleary

Blog Posts

For Mattie Ford, a Tennessee native, using her hands to climb rock walls, dig vegetables & write intricate papers were all a way to grow both academically & professionally at UM's Center for the Study of Southern Culture. Read about her Journey- https://bit.ly/3vtE32k

America’S History Of Health Disparities: How Does This Affect The Future Of Healthcare In Mississippi?, Zuri O. Dixon Omere, Jazmin King

Honors Theses

America’s healthcare system runs rampant with healthcare inequalities that have an alarming effect on minorities and people of color. In order for people of color and marginalized groups to receive proper care and treatment, more attention needs to be brought to these inequalities. For example, Covid-19 reflected the health inequalities that are present in this country; minorities were more likely to become hospitalized due to Covid-19 than other non-minorities. In addition, minorities in women’s health, specifically black women, have been affected in various ways that are related to the inequalities in medicine like dying during childbirth and improper care. This …

Oxidized, Ashley Smith

Graduate Theses in Studio Art

No abstract provided.

Saying Yes To (Mostly) Everything - Journey To Commencement, Lydia Lagarde

Journey to Commencement

Richard Springer opened up to a lifetime of experiences at Ole Miss.

Sparking Confidence Through Competition - Journey To Commencement, Nell Floyd

Journey to Commencement

Ole Miss prepares Lauren Taylor to embark on graphic design career.