Digital Commons Network^™

Methylene Blue As Light And Reactive Oxygen Species Sensitive Ligand: Appicability In Hybrid Drug And Material Synthesis, Huy Dao

Electronic Theses and Dissertations

Methylene blue (MB) with a 10-N-carbamoyl linkage was discovered and developed as a multifunctional far-red (660 nm) photocleavable ligand capable of rendering a series of MB conjugated compounds with off-to-on fluorescence switch properties through the controlled release of MB. The released MB was successfully demonstrated to be an effective photosensitizer, imaging probe, and therapeutic agent. The complete release of MB was achieved with a cumulative light dose of 15 J/cm2. The photosensitivity was demonstrated to be dependent on the type of chemical bond at 10-N of the phenothiazine ring which links MB to a side group. Specifically, the urea bond-based …

Traumatic Life Experiences And Their Impact On Factors Pertinent To Leadership Effectiveness In School Principals, Derrick D. Hardaway

Electronic Theses and Dissertations

Many schools across the nation are not making adequate achievement or growth goals from year-to-year. This leads to high principal turnover rates and instability in the learning environment which profoundly impacts student achievement. Currently, most efforts in schools are aimed at raising student achievement, implementing equitable practices, and limiting barriers. While these are critical actions for closing the achievement gap, the principal’s role in this process is vitally important. Therefore, this quantitative study explored how trauma affects factors that are pertinent to leader success in school principals. To determine the impact trauma has on leadership qualities, this study examined the …

Decreasing Discipline Disparities Among African-American Males: An Applied Research Study On The Effects Of Developing Culturally Responsive Teaching Practices Among Teachers And Equipping Students With Added Supports, Reginald Maurice Herrington

Electronic Theses and Dissertations

Schools and school leaders are charged to provide equitable educational opportunities and ensure the success for all students no matter their scholastic ability giving students access to an education that is culturally responsive. Despite this charge, African-American male students receive exclusionary punishment at disparaging rates which contributes to the widening achievement gap between white and black students. The purpose of this applied research study was to decrease the rate at which African-American males are referred to the office. This study analyzes the implementation of two elements: engaging teachers in a book study on culturally responsive teaching strategies and targeted counseling …

The Role Of Social Anxiety In Prosocial Behavior Following Exclusion, Hannah Friedman

Electronic Theses and Dissertations

Social anxiety (SA) causes significant distress and impairment in several areas of daily life. Individuals with SA experience increased rates of exclusion and have more difficultly forming meaningful interpersonal relationships. Exclusion is associated with increased SA and motivations for social withdrawal in emerging adulthood. In non-SA individuals, the desire for compensatory social interaction following exclusion often produces prosocial behaviors (e.g., increased effort to help the group). Prosocial behavior levels following exclusion are not uniform, however, as an individual’s response may vary depending on the type of exclusion experienced. Although previous work has observed decreased levels of prosocial behavior in non-SA …

As Close As I Can Get To It, Kathryn Leland Henricks

Electronic Theses and Dissertations

A collection of poems.

1.5 Generation Korean-American Young Adults' Bilingualism And Their Identity In The U.S., Hanna Kim

Electronic Theses and Dissertations

Since the 20th century, particularly post-1965, there has been rapid growth in the Korean-American population in the U.S. The number of 1.5 generation Korean-Americans has also increased. 1.5 generation Korean-Americans can take advantage of learning both languages and cultures in the two countries which can help them become bilingual and bicultural individuals. However, previous studies about the language experience and identity of Korean-Americans have mainly focused on the first or second-generations (Kang, 2013; M. Park, 2005) rather than 1.5 generations. Some of these studies have focused more on children at an early age (E. S. Park, 2005; Zhou, 1997) instead …

The Influence Of Emotion Regulation And Family Involvement On Diabetes Distress Among Adults With Type 2 Diabetes, Patric Justin Leukel

Electronic Theses and Dissertations

Adults with diabetes frequently experience diabetes related distress which is associated with negative health outcomes. Family members are commonly involved in patients’ diabetes self-management. However, family involvement can have harmful and/or helpful effects on patients’ diabetes outcomes. Difficulties in regulating emotions may play a role in patients’ interactions with family members and experience of diabetes distress. This study examined the role of emotion regulation and type of family involvement in diabetes distress among 370 adults with type 2 diabetes. Two separate three-step sequential linear regression models were used to test the main and interactive effects of harmful and helpful family …

Increasing Reading Achievement: An Applied Research Study On The Effects Of Implementing An Independent Reading Time At Lester Elementary School, Sherna Jones

Electronic Theses and Dissertations

Reading proficiency is an important skill and demonstrated proficiency is required by the Mississippi’s Literacy Based Promotion Act of 2013 for third graders to be promoted to fourth grade. Reading proficiency at third grade also has serious implications for lifelong outcomes. The purpose of this applied research project was to increase reading achievement for the second and third grade students of Lester Elementary, specifically by exploring the effects of increased time spent reading, access and self-selection of books, and motivation to read on reading proficiency. The analysis of pre- and post- STAR data was used to determine if proficiency rates …

The Value Of Participating In Cooperative Education, Megan Upchurch Miller

Electronic Theses and Dissertations

The benefits of experiential education are well known and a popular discussion topic on college campuses. The value of participation in a co-op work experience is recognized by employers, but not necessarily by the students they are hoping to hire. This study sought to determine whether or not students who did participate in a co-op found their experiences to be beneficial to their personal or professional growth.

Academic Support Systems And College Readiness For Black Male Student Athletes, Derek Lovell King

Electronic Theses and Dissertations

High school athletics is a major aspect of today’s educational landscape. Sports generate revenue, galvanize communities, and provide opportunities for widespread exposure. For the black athlete, sports generally represent an opportunity to go to college. With the pressure of academic accountability, increased athletic competitiveness, and the impact of future prospects, high schools have to be innovative in order to optimize the academic experience, particularly for Black male athletes.

The impact of high school academic support systems, particularly their capacity to increase the college readiness of Black male athletes, has not been adequately examined. College GPA, college persistence rate, and college …

What Remains: Telling The Story Of Irene Taylor's Murder, Christian Leus

Electronic Theses and Dissertations

This written thesis serves as a companion piece to What Remains, a six-part audio podcast telling the story of Irene Taylor, a 19-year-old sharecropper’s daughter who was murdered in Altheimer, Arkansas, in 1939. The investigation of the murder, which garnered national press attention, ended with the conviction and execution of Sylvester Williams, a 22-year-old Black man also from Altheimer. This paper expands on the contextual research done in support of the podcast, including close readings of newspaper coverage and fictionalized magazine reports of the case; an examination of the Delta environment’s racialized history and its impact on the lives of …

Building Teacher Capacity As A Pathway To Equity For First-Grade Spanish-Speaking English Learners: An Applied Research Study, Mary Greenlee Moak

Electronic Theses and Dissertations

ABSTRACT The teaching of English Learners, one of the fastest-growing subgroups in American Public schools, is a task American classroom teachers are ill-equipped to handle. As students from a variety of language backgrounds move from metropolitan areas of the country to more rural locales educational leaders must equip teachers to integrate language acquisition with content instruction. Failure to do so will result in compounding learning gaps among English Learners as the language barrier prevents them from gaining content knowledge. Based in a Mississippi school with a growing population of English Learners comprising over a quarter of the school’s population, this …

Hot-Melt Extrusion Based Fused Deposition Modeling 3d Printing Of Atorvastatin Calcium Tablets: Impact Of Shape And Infill Density On Printability And Performance, Preethi Mandati

Electronic Theses and Dissertations

The main objective of the current research is to investigate the effect of shapes (heart and round shape tablets) and infill densities (50% and 100%) on drug release profiles of tablets prepared by hot melt extrusion (HME) coupled fused deposition modeling (FDM) technique. Two different commercial FDM 3D printers with different filament feeding mechanisms were evaluated for suitability of printing. Drug-loaded filaments of 1.5 mm and 2.5 mm diameters were extruded using Process 11 mm HME, using atorvastatin as a model drug and Kollicoat® IR, Kollidon® VA64, Kollidon®12PF, and Kolliphor® P407 as hydrophilic polymers. Filaments of Kollicoat® IR in combination …

Subcutaneous Delivery Of Albumin, Vy Nguyen

Electronic Theses and Dissertations

An increasing number of protein drugs are used in the clinic to treat a broad range of diseases. However, because of their large molecular sizes and high hydrophilicity, protein drugs are not orally bioavailable, which commonly require intravenous, intramuscular or subcutaneous injection. Thermosensitive polymers have been widely investigated as in situ depots for sustained drug release delivered through subcutaneous route.Albumin is the most abundant proteins in bloodstream. It has long half-life (19 days in human) and plays important roles such as acting as carrier for fatty acids, amino acids, waste products and medical compounds. Albumin has been studied for decades …

Effects Of Nonnative Phonotactic Constraints On The Perception Of Nasal-Initial Consonant Clusters, Msafiri Otonya

Electronic Theses and Dissertations

This study examines the effects of non-native phonotactic constraints on the perception of nasal-initial consonant clusters (NICC), specifically whether native English speakers can perceive NICC as accurately as native Swahili speakers. The ABX task was conducted over Zoom to test L1 English speakers (N=12) and L1 Swahili speakers (N=12). Stimuli with four conditions were used: 1) The stimuli had one of the three nasal sounds (/m/, /n/, and /?/) in word-initial consonant clusters; 2) The stimuli had NICC composed of a nasal sound followed by either a voiced or voiceless consonant; 3) The consonant clusters were composed of sounds that …

Equity, Social Justice, And Ethical Responsibility In Higher Education: Voices Of Business Students At A Pervasivley Sectarian University, Van Brooks Poole

Electronic Theses and Dissertations

This proposed study explores the perceptions and experiences of business students who attend a pervasively sectarian university in the South (MPSU) regarding their perceptions of equity, social justice, and ethical responsibility through their experiences on campus and in their academic program. This study will discuss socio-political influences at the national, state, and local levels and examine existing university policies and practices to identify recommendations for organizational change using Lewin’s unfreezing model as a theoretical framework.

The Trajectory Of Resilience, Meaning In Life, Social Support, Posttraumatic Growth, And Posttraumatic Stress For Emerging Adult Trauma Survivors, Marcela C. Weber

Electronic Theses and Dissertations

BACKGROUND: The literature suggests the relationship between posttraumatic growth (PTG) and posttraumatic stress (PTS) is curvilinear, and that type or severity of trauma may affect this relationship. The relationship between depression, anxiety, and PTG is understudied. It is well established that meaning in life predicts PTG, PTS, and resilience, yet most of the research has measured general perceived meaning rather than meaning beyond-the-self, specifically, which was initially theorized by mid-century Humanistic psychologists. Mixed findings about whether searching for meaning is beneficial or harmful suggests potential moderators of search for meaning should be explored. METHOD: Participants (N = 628) were emerging …

The Bake Sale: Fundraising And Social Justice In The 21st Century, Kelly E. Spivey

Electronic Theses and Dissertations

Bake sales have recently come to the forefront of our consciousness as a method of fundraising for social justice but the practice’s history reaches back to the 18th century. A readily available tool for women, baking was put to work to raise money for voting rights in the early 20th century. Less than fifty years later, bake sales appeared as a key fundraising tool for the civil rights movement. The reappearance of bake sales today stems from several factors, including the presidential election of Donald Trump in 2016, the appearance of COVID-19 in the United States in early 2020, and …

Microbial Community Responses To Salinification: Applications In Climate Change And Extreme Environments, Eric Weingarten

Electronic Theses and Dissertations

Sediment microbial community responses to elevated salinity are important in predicting the effects of sea level rise as well as in understanding those communities that can thrive in extreme environments. In this dissertation, I use natural and field experiments to investigate how salinity influences microbiome structure in coastal wetlands. Through the use of amplicon sequencing, I demonstrate that there are compositional differences between the microbiota of four wetland salinity classes: limnetic, oligohaline, mesohaline, and polyhaline. These results were reciprocated in a microcosm study exposing freshwater sediment to meso- and polyhaline conditions, showing that communities shifted proportionally to the magnitude of …

Ceramic Analysis Of The 2019 Excavations Of Ely (44le12) Mound Site, Lee County, Virginia, Shannon Medah Wooten

Electronic Theses and Dissertations

The Mississippian frontier in southwestern Virginia is a relatively unexplored area. This area was occupied by Mississippian and Radford locals, creating a crossroads between the two groups. The Ely Mound site is a Mississippian frontier site that can help understand the influence of Mississippian and Radford cultures on the development of chiefdoms. This thesis will analyze the ceramics from the mound test unit and shovel test survey of the 2019 excavation at Ely located in Lee County, Virginia. The temper patterns were used to understand the date and use of the site. The purpose of this thesis is to analyze …

Soul Liberation: Black Christian Intellectual Engagement With Black Power, Jemar Tisby

Electronic Theses and Dissertations

Throughout the Civil Rights movement, Black Christians figured prominently as clergy, leaders, and foot soldiers in the struggle. As a result, the presence of Black Christians during this phase of the Black activism is well-documented by historians. During the Black Power era, however, scholars tend to overlook the ongoing presence and significance of Black Christians in the movement. Soul Liberation corrects this omission by studying Black Christian engagement during the Black Power movement of the 1960s and 1970s.

Lining-Out And Performance Practice Of The Dr. Watts Hymn- Lining Tradition In Three Selected African American Missionary Baptist Churches In The Northern Mississippi Delta Region, Kelvin K. Towers

Electronic Theses and Dissertations

The purpose of this descriptive study is to analyze the performance practice of lined-hymns that are sung in three selected African American Missionary Baptist churches located in the Northern Mississippi Delta region. ‘Dr. Watts’ lined-hymn singing has survived in some African American church denominations for approximately 150 years without the availability of a standardized printed musical notation source. Focus of the investigation is guided by five questions exploring the historical context, liturgical function, musical characteristics, performance practice, and method of learning of this musical tradition. Further examined are the role of the song leader, and cultural beliefs and philosophical differences …

Design And Optimization Of Alkali-Activated Binders For Construction Applications, Rami Khalil Al-Sughayer

Electronic Theses and Dissertations

This research is focused on investigating the potential use of by-product waste and natural materials for improving alternative green cement mixes. The primary objective of this research is to expand the use of sustainable and more environmentally friendly cement alternatives, by enhancing their performance for construction applications. To activate the binding properties of binder under investigation, they have to be mixed with an alkaline solution in specific quantities. To broaden the use of these binders in the construction industry, parameters such as the effect of different chemical activators types and dosages, curing times and temperatures, processing techniques, and the chemical …

Epigenetic Regulation In Brevundimonas Subvibrioides And Comparison With The Caulobacter Crescentus Model, Satish Adhikari

Electronic Theses and Dissertations

Epigenetics is a form of DNA methylation-based gene regulation. The CcrM methyltransferase and transcriptional regulator GcrA, constitute an epigenetic regulatory system well-conserved throughout the Alphaproteobacteria. The regulatory targets of GcrA and CcrM were identified in the Alphaproteobacterium Brevundimonas subvibrioides, and then compared to those of its close relative Caulobacter crescentus. Both these bacteria belong to the same family and inhabit the same environment. Although the regulators themselves are highly conserved, the genes they regulate are vastly different. GcrA directly regulates 204 genes in C. crescentus, and though B. subvibrioides has orthologs to 147 of those genes, only 48 genes retained …

The Perceptions That Um First-Generation College Students Have Regarding The Impact Of Campus Engagement On Their Success At The Institution, Martin B. Fisher

Electronic Theses and Dissertations

First-generation students are often underprepared for college and have lower persistence rates (Balemian & Feng, 2013), and they face a unique set of challenges in their transition to college that many of their peers do not (Pelco, Bell, & Lockeman, 2014). Consistent with national statistics, data obtained from UM’s Office of Institutional Research, Effectiveness, and Planning indicate first-generation students at UM persist and graduate at lower rates than their peers whose parents have a bachelor’s degree.

There are many reasons why first-generation students have lower success rates, and, for some students, a lack of engagement is one of them (Pascarella, …

Fabrication And Characterization Of Ocular Inserts By Hot Melt Extrusion And 3d Printing, Meghana Mokashi

Electronic Theses and Dissertations

Hot melt extrusion (HME) has emerged as a viable approach for a wide range of pharmaceutical applications over the last few decades. The HME method is more efficient than other traditional technologies due to its high throughput, low residence time, lack of organic solvents, and a combination of intensive mixing and controlled temperature. Because of the ability to construct complex and personalized dosage forms depending on the requirements of the patient, three-dimensional printing (3DP) is an emerging approach in the fabrication of pharmaceutical dosage forms. The objective of the current study is to fabricate Lidocaine HCl ocular inserts by HME …

A Numerical Study Of The Effects Of Time-Varying Streambed Conductivity On Groundwater – Surface Water Interactions During Storm Events, Jiayu Fang

Electronic Theses and Dissertations

Streambed conductivity is widely recognized as a vital parameter controlling the stream-aquifer exchange. Many field measurements have revealed that temporal variation of streambed conductivity is rapid and dramatic during floods. However, previous numerical studies either assumed streambed conductivity as steady over storm events or focused on time-varying streambed conductivity during low-stage periods. This study aims at bridging this gap by both incorporating time-varying streambed conductivity into a numerical model of groundwater (GW) – surface water (SW) interactions and simulating them under different flooding conditions, making this dissertation the first modeling study to explore combined effects of high-stage events and time-varying …

Come As You Are: Islamic Religiousness As A Context For Mental Illness Beliefs And Treatment, Elijah Phoenix Mudryk

Electronic Theses and Dissertations

The United States is home to approximately three million Muslim-Americans, a diverse and growing demographic group that has woven itself into the fabric of American life. Hailing from many regions around the world, Muslims in the U.S. are varied in racial and ethnic backgrounds and not dominated by any particular race or ethnicity. National pride and a strong religious identity are shared aspects among U.S. born Muslims and immigrants alike (Pew, 2018). In addition to the typical challenges of daily life, Muslim-Americans have experienced high levels of religious and ethnic discrimination. Post-9/11, Muslim-Americans suffered a 1600% increase in reported hate …

Exploring Copper Active Sites In Biology With Relevance To Alzheimer's Disease And De Novo Designed Biocatalysts, Suchitra Mitra

Electronic Theses and Dissertations

Copper is one of the most abundant and less toxic metal on earth. In nature, a variety of proteins have copper in their active site structure. Copper bound to amyloid proteins are implicated to play pathophysiological roles in neurodegenerative diseases. On the other hand, copper containing metalloenzymes in Nature catalyze important biochemical reactions. Cu containing metalloenzymes play a significant role in a variety of functions viz. electron transfer, oxygen reduction, oxygen transport, and substrate oxidation owing to the readily available redox states of Cu+/Cu2+. While Cu bound to amyloid proteins that are often referred as intrinsically disordered or misfolded proteins …

Acoustic Bessel And Vortex Beams: Forces And Refraction, Xudong Fan

Electronic Theses and Dissertations

Non-contact manipulation techniques or tweezers devices are invaluable for applications in physics, chemistry, biology, and engineering. Acoustic tweezers using either standing waves or focused beams have been investigated for more than a few decades with advantages of label-free operation, noninvasiveness, and biocompatibility when compared with the optical, magnetic, and electrical counterparts. Here, a new type of acoustic tweezers (i.e. acoustic tractors) is studied using acoustic Bessel and vortex beams that are able to pull objects against the beam's propagation over centimeter ranges. Stable acoustic tractors require transversely stable trapping in addition to axially negative pulling. Hence, the transverse forces acting …