Digital Commons Network^™

Serving Children Experiencing Parental Substance Misuse In The Elementary Classroom: Training Modules For Pre-Service Teachers, Lauren Biando

Honors Theses

The purpose of this capstone is to explore how the needs of children whose parents misuse substances are often left unmet and to develop training modules for pre-service teachers. The need for teacher training on how to identify and intervene to meet students’ basic needs is essential as Maslow’s hierarchy of needs explains that children cannot build self-esteem, reach self-actualization, and focus on learning if their basic needs are not met. This capstone reviews the literature on the impacts that parental substance misuse has on children and the interventions that have been tried to help these children cope with the …

An Examination Of Cardio-Vascular Patients’ Experiences In A Rural Food Prescription Program, Julia Hansen

Honors Theses

The burden of diet-related chronic diseases in rural communities has prompted the implementation of food prescription programs in rural areas to investigate the impact of more affordable and accessible fresh produce on these vulnerable populations. Because there is little research on the impact of food prescription programs on cardiovascular patients in rural areas, this study will focus on how food prescription programs can benefit this at-risk population. Another goal of this study is to receive feedback from participants to improve food prescription programs to better suit cardiovascular participant needs. To accomplish these goals, a series of questions were asked to …

Your Money Or Your Life: A Study Of Medical Debt In The Southeastern United States, Grace Barrett

Honors Theses

A major issue has emerged from the U.S. healthcare system: medical debt. Medical debt is a serious problem in the U.S. that often cripples those who received healthcare services, but are unable to pay the bill. The most common scenario is when an unexpected major medical issue occurs, e.g. a heart attack, an automobile accident, cancer or anything requiring an emergency room visit. These hospital visits often result in very large, very unexpected expenses. These expenses are ultimately owed to the healthcare provider by the patient (or the patient's insurance policy) and increasingly, cause lifelong financial stress to those who …

Are We Ready: Envisioning An Inclusive Higher Education Program For Individuals With Intellectual And Developmental Disabilities At The University Of Mississippi, Bailey Beaird

Honors Theses

An inclusive higher education program (IHEP) exists for individuals with intellectual and developmental disabilities (I/DDs) to foster academic success, employment equipping, interpersonal skill development, and active participation and value validation in the community. Establishing an IHEP can benefit current university students, faculty, and staff, and individuals with I/DDs and their families to create a more informed, inclusive environment. The University of Mississippi (UM) does not currently have an IHEP. Therefore, my advocacy initiative seeks to provide an opportunity for individuals with I/DDs to receive a college education and experience at UM. For two and a half years, I independently researched …

An Examination Of The Accounting Profession In Relation To Socioeconomic Factors, Amelia Hunter

Honors Theses

This thesis contains 6 separate case studies that relate to accounting principles and relevant current topics that can affect the accounting industry. These case studies were assigned by Dr. Dickinson during the fall and spring semesters of the Honors Accountancy 420 course. During the fall semester, the class was divided into research groups and were each assigned a fortune 500 company that would be the subject of the case studies. My group was assigned to Flowers Foods, and we were given the opportunity to approach each case study as if the company was a client, and we were the accountants. …

Graduates: Stay Focused, Remember Ole Miss And Find Happiness Within, Emily Howorth

University of Mississippi News

When the Class of 2024 graduates Saturday (May 11), they'll complete one journey and embark on the next. Just like those who came before them, these new graduates are ready to grow the legacies they've started at the University of Mississippi.

Early Developmental Exposure To Δ9-Tetrahydrocannabinol Causes Latent Behavioral, Growth, And Bioenergetic Effects In Danio Rerio, Astra Hahm

Honors Theses

Early developmental exposure to Δ9-tetrahydrocannabinol causes latent behavioral, growth, and bioenergetic effects in Danio rerio

(Under the direction of Dr. Kristine Willett)

Δ9-tetrahydrocannabinol (Δ9-THC) is used during pregnancy to mitigate symptoms such as nausea, pain, and insomnia. It is established that Δ9-THC exposure early in life causes adverse effects in children’s development including behavioral disorders. Our goal was to determine the latent and generational impacts on growth, behavior, and mitochondrial bioenergetics following exposure to Δ9-THC. Wildtype (5D) zebrafish were exposed to 0 (0.05% DMSO), 0.08, 0.4, or 1 µM Δ9-THC from 6-96 hours post-fertilization (hpf), then subsequently raised in clean …

Childhood Food Insecurity As It Relates To Adult Intuitive Eating Patterns, Lily Langley

Honors Theses

Many American families struggle with food insecurity and do not have the economic capabilities to obtain a sufficient quantity of nutritious food. Childhood food insecurity is associated with negative health effects and altered relationships with food as an adult. Intuitive eating, a non-diet framework that emphasizes mindful eating, may attenuate these effects. It includes unconditional permission to eat, eating for physical rather than emotional reasons, reliance on hunger and satiety cues, and body-food choice congruence. Previous research has not examined whether childhood food insecurity can affect one’s ability to eat intuitively as an adult. The goal of this study was …

Jtc 24: Lifting Others, Emily Howorth

University of Mississippi News

This story is part of the 2024 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

The Emergence Of Approachable Luxury In The Grocery Industry, Joseph Curcio

Honors Theses

This thesis examines various trends in the grocery industry that have led to the new age grocer. These trends are centered around the emergence of approachable luxury products on grocery shelves and new grocery stores centered around an approachable luxury approach. Due to the subjective nature of the term “luxury,” it is hard to define, but multiple academic definitions from the Journal of Business Research are analyzed.

The timeline of the luxury grocery is outlined – beginning with traditional Iberian shops to the emergence of the new curated grocer to the revitalization of big box stores. The thesis includes psychological …

Issue 442: May 2-16, 2024, The Local Voice

The Local Voice

No abstract provided.

Pharmacy Matters - May 2024, Umiversity Of Mississippi School Of Pharmacy

Pharmacy Matters Newsletters

Featured Stories: "Journey to Commencement: Victoria Green Makes Good on a Promise", "Donors Break Giving Day Record", "Pharmacies Could Create Custom Drugs with 3D-Printed Medication", "Pharmacy Researchers Review Reasoning for Nordic Ashwagandha Ban", "Pharmacy Federal Grant to Propel Vaccine Technology Research".

An Examination Of Products That University Of Mississippi Students Consume For Managing Their Stress, Kiersten Rickard

Honors Theses

Students are notoriously one of the most stressed groups in our society. Stress is a complex topic; causes, mitigation methods, and manifestations of stress all vary in an individual. Being that stress is an universal experience, this research capitalizes on the importance of stress and the methods used to mitigate stress. This study looks at, among other ideas, stress on the University of Mississippi campus in regards to demographics and the products (caffeine, sleep aids, over the counter medicines, stress supplements, and CBD) that students use. Results demonstrate that, overall, higher stress levels correlate to higher product usage rates. The …

How Witnessing Domestic Violence Affects The Future Of Children: An Exploratory Study, Victoria Cleckler

Honors Theses

Domestic violence (DV), also known as Intimate Partner Violence (IPV), is a widespread issue that affects many people, families, and communities, with one in four women and one in nine men falling victim to domestic violence each year in the United States. However, these statistics only consider what has actually been reported. More than 44% of domestic violence cases go unreported each year. It can be inferred that a drastic number of children are also affected. Children who witness domestic violence are indirect victims of DV, as they experience psychological and emotional turmoil simply by witnessing the abuse. However, there …

Metabolite Profiling Of Functional Fungi Strains Of Hericium Erinaceus & Cordyceps Militaris: Using Phenotypes, Untargeted Metabolomics By Mass Spectrometry And Cell-Based Assays, Julie Daoust

Oxford ICSB

Mushrooms have a long tradition of use as medicinal and functional ingredients however the lack of development in testing methods currently limits our ability to characterize these products. Selecting the right strain or processing method is currently challenging given the lack of commercially available analytical methods to detect or quantify secondary metabolites with therapeutic endpoints. Very little is known about the variability of these metabolites between strains of the same species and between identical strains grown in different conditions therefore an untargeted analytical method was needed to adequately assess impact of strain genetics and growing methods for M2 Ingredients cultures …

Re-Discovery Of Fungi, Christopher Hobbs

Oxford ICSB

This will be a very concise overview of the laboratory and clinical work that has been published on the health and medical benefits of medicinal mushrooms and mycelium. Medicinal mushroom and mycelium-based products currently on the market will be critically reviewed, specifically focusing on identifying the 5 most important constituent groups intensive world-wide research has identified as providing the intended benefits of these products, and what leading companies as well as startups are doing to insure their products contain them in meaningful amounts.

Evaluation Of Botanical Extracts For Cytochrome P450 Inhibition Mediated Drug Interactions, Angela I. Calderón, Zarna Raichura, Kabre Heck, Jaewoo Choi, Mikah Brandes, Cody Neff, Claudia Maier, Amala Soumyanath, Robert Arnold

Oxford ICSB

There has been remarkable growth in consumption of botanical dietary supplements (BDS), making it important to understand the safety profile of BDS with respect to the pharmacokinetic properties for any potential of botanical-drug interactions. One such botanical interactions which has gained significant attention involves inhibition of cytochrome P450 (CYP450) enzymes by co-administered drugs. Our study involved examining two widely used botanicals, ashwagandha and açaí for any potential inhibition of CYP450. Four different ashwagandha extracts were tested, resulting in inhibition of CYP2B6 with IC50 < 100 µg/ml of extract and showed potential of time-dependent inhibition for CYP2C9 and CYP2D6 with an IC50 ~ 200 µg/ml of extract. In the case of açaí, seven different extracts were tested and only CYP2C9 was inhibited. The acidic methanol extract of açaí formulation showed an IC50 of 0.3 µg/ml of extract indicating potent inhibition of CYP2C9, while the methanol (IC50 ~ 91.75 µg/ml) & ethanol extracts of Mountain Rose açaí powder showed weak inhibitory effect with an IC50 < 100 µg/ml of extract for CYP2C9. The results reflect that both botanical extracts showed potential of CYP450 inhibition, suggesting that compounds in BDS can prolong the half-lives of medications leading to extended action or toxicity. Next step involves, testing subfractions of these extracts to identify the compounds responsible for the observed inhibition.

Screening Of Medicinal Herbs To Predict The Potential Perpetrators Of Herb-Drug Interaction, Ikhlas A. Khan, Amar G. Chittiboyina, Shabana Khan, Bill Gurley, Islam Husain

Oxford ICSB

Over time, the popularity and consumption of herbal medicine and its products like nutraceuticals, botanical drugs, and dietary supplements have increased immensely. Parallelly, several health issues associated with the overconsumption of these products have also been raised, which has attracted enormous attention. Herb-drug interaction (HDI) is a health issue caused by herbs or phytochemicals that modulate the homeostasis of drug-metabolizing enzymes (CYPs) and transporters, thus altering the pharmacokinetic of clinical drugs. To date, only a few medicinal herbs, such as Hypericum perforatum, Hydrastis canadensis, Glycyrrhiza glabra, and Camellia sinensis etc., were recognized as HDI perpetrators. However, many need to be …

New Natural Product Certified Reference Material Resources Supported By The Nih Office Of Dietary Supplements, Adam Kuszak, Zoe Ruan, Linda Smith, Sarah Ajaz, Uma Srennivasan, Sabrina Giddings, Daniel Beach, Pearse Mccarron, Stephen Wise

Oxford ICSB

The NIH Office of Dietary Supplements (ODS) Analytical Methods and Reference Materials (AMRM) Program supports the development of tools that promote and facilitate rigorous and reliable characterization of dietary supplement (DS) identity, composition, and purity, as well as assessments of authenticity and contamination of botanical and other natural product raw materials and finished products. AMRM goals are accomplished through development and validation of quantitative and qualitative methods, production of certified reference materials (CRMs), and support of dietary supplement focused laboratory quality assurance programs. Recent advances in DS analytical resources supported by AMRM include an expanded availability of CRM calibration solutions …

April 18, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Session E Overview Of The U.S. Cosmetics Regulatory Framework, Jannavi Srinivasan

Oxford ICSB

Cosmetic products in the U.S. has been regulated by the Food and Drug Administration (FDA) according to the Federal Food, Drug, and Cosmetic Act which has provided for FDA’s regulation of cosmetics since 1938. The Modernization of Cosmetics Regulation Act (MoCRA), enacted in December of 2022, significantly expanded and reformed regulations overseeing cosmetics in the U.S. Included in MoCRA among other provisions, are facility registration and product listing, reporting of serious adverse events, and a requirement that FDA propose a rule for good manufacturing practices. This presentation will provide an overview of cosmetics regulations including the major provisions of MoCRA …

Introduction To The Premarket Review Of Human Food Ingredients In The United States And Concepts In The Safety Assessment Of Novel Plant-Derived Ingredients, Troy Hubbard

Oxford ICSB

Premarket regulation of ingredients added to food is a key pillar ensuring the safety of food as it allows the opportunity to address potential safety concerns prior to consumer exposure. In the United States, food and color additives are substances that are intentionally added to food and are subject to pre-market approval by the Food and Drug Administration (FDA) and require a listing in the Code of Federal Regulations, unless the intended use of the substance is generally recognized as safe (GRAS), among qualified experts. GRAS is not an inherent property of a substance, as is often misunderstood; rather, it …

Chemistry, Biology, And Safety Of Volatile Organics From Aromatic And Medicinal Plants, Nicole Stevens

Oxford ICSB

Introduction Sleep is an important foundation of health, yet the U.S. Centers for Disease Control (CDC) notes that about 30% of adults to not get the recommended minimum of 7 hours’ sleep per night. Prescription treatments may help, but they carry risks such as side-effects, dependency, and medication interaction. Natural botanical extracts are a therapeutic possibility for improving sleep quality, but additional research is needed on their efficacy and safety. A system of natural products based on lavender was developed and tested in a human clinical study to evaluate effect on sleep, blood and safety markers, and gene expression modulation …

One-Class Modeling For The Authentication Of Actaea Racemosa And Evaluation Of The Variation Between Botanical Reference Materials, James Harnly

Oxford ICSB

One-class modeling based on soft independent modeling of class analogy (SIMCA) is a simple but powerful method for comparing the chemical composition of botanical materials using non-targeted chromatograms (GC, LC) or spectra (IR, MS, NIR, NMR). The methodology is available on any commercial chemometric platform. Authentication is based solely on the characteristics of the botanical material of interest. Detection of adulteration is determined for each variable and requires no identification of adulterants. Some highly characterized botanical reference materials (BRMs) may account for species, cultivar, and year and location of harvest while more generic BRMs may have minimal characterization. All of …

April 11, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Examining Confidence In Scientific Literacy Amongst General Biology And General Chemistry Students, Amy Sullivan

Honors Theses

Scientific literacy is a term used to describe a person’s ability to understand scientific concepts, read and write those concepts, and link those concepts to situations outside of the classroom in order to make informed decisions in their daily lives. This research paper details a study observing how scientific literacy confidence varies among general biology and chemistry students at the University of Mississippi. The goal of this research is to determine if students in general biology and chemistry classes will have similar self-reported confidence in their science literacy. This research took place at the University of Mississippi amongst Biology 160/161 …

Influences Of Dietary Enrichment In Juvenile And Adult Male Zebra Finch (Taeniopygia Castanotis) On Cheek Patch Growth And Color, Carley Craig, Mathew Thibodeaux, Mary Tharp, Gabrielle Morris, Woodward Young, Belinda Bagwandeen, Lainy B. Day

Neuroscience Research Showcase

Zebra finches (ZF) are sexually dimorphic. In captive ZFs, enriched diets increase cheek area and alter color, increasing adult male attractiveness. In the wild, breeding and brooding occur when proteinaceous seeds available. Our experiment tests whether supplemental egg food benefits captive non-breeding adults and juveniles.Pre-experiment, adults fed eggs, cuttlebone & bread 2x week. Other facets of our experiment showed enriched diet led to decreased reactive CORT levels and increased body mass, with the largest increase in females.

All authors are affiliated with the University of Mississippi Department of Biology and Neuroscience Minor.

Issue 440: April 4-14, 2023, The Local Voice

The Local Voice

No abstract provided.

Nhm 728: Advanced Survey Data Analysis, Yunhee Chang

GMAS Course Syllabi

No abstract provided.

Brain Awareness Week Focuses On Ethics, Impact Of Technology, Edwin Smith

University of Mississippi News

OXFORD, Miss. – Two renowned neuroscientists will discuss the development and impact of neurotechnologies and neuroengineering and students will present their own original research during annual Brain Awareness Week events April 2-5 at the University of Mississippi.