Digital Commons Network^™

Mental Health Risks Differentially Associated With Immunocompromised Status Among Healthcare Workers And Family Members At The Pandemic Outset, Andrew J. Smith, Hannah Wright, Brandon J. Griffin, Anandi C. Ehman, Kotaro Shoji, Tiffany M. Love, Ellen Morrow, Amy Locke, Megan Call, Patricia K. Kerig, Miranda Olff, Charles C. Benight, Scott A. Langenecker

Faculty and Student Publications

The mental health of healthcare workers (HCWs) is critical to their long-term well-being and future disaster preparedness. Goal 1 of this study was to identify rates of mental health problems experienced by HCWs. Goal 2 was to test a model of risk stemming from pandemic-related stressors and vulnerability factors. This cross-sectional study included HCWs (N ​= ​2,246 [1,573 clinical providers; 673 non-clinical staff]) in the Rocky Mountain West who voluntarily completed an online survey in April/May 2020. Respondents completed measures for traumatic stress symptoms, depression, anxiety, alcohol use, and sleep. Logistic regressions stratified by professional role (clinical versus non-clinical) were …

Employee Benefit Plans, August 1, 2021; Audit And Accounting Guide, American Institute Of Certified Public Accountants (Aicpa)

Industry Guides (AAGs), Risk Alerts, and Checklists

No abstract provided.

Cafer Named Director Of Center For Population Studies, Edwin B. Smith

University of Mississippi News

Expert overseeing census, other data important to meeting research needs

School Of Pharmacy Intellectual Property Report Fy21, Fourth Quarter Report, Soumyajit Majumdar

U. S. Patents, School of Pharmacy

School of Pharmacy Intellectual Property Report FY21, Fourth Quarter Report (as of 6/30/21)

Research News, Publications, 2021, Volume 2, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of April 1 through June 30, 2021

Research News, Grants, 2021, Volume 2, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during April - June 2021

Pharmacy Alumnus Honors Former School Administrators With Scholarship, Whitney Tarpy

University of Mississippi News

David Newton's gift will help aspiring pharmacists and teachers

Nsf Grfp Information Session, Jason Hale

ORSP Presentations

NSF Graduate Research Fellowship Program (GRFP) Information Sessions

• Jason Hale, M.S., Director of Research Development, ORSP
• Robert Doerksen, Ph.D., Associate Dean of the Graduate School
• Vivian Ibrahim, Ph.D., Associate Professor of History; Director of the Office of National Scholarship Advisement

with Annette Kluck, Nikki Reinemann-Gross, Thomas Werfel, Cole Stevens, Courtney Roper, Rachel Greenspan, & Hoang V. Le

Andrew Newby Named George W. Bush Institute Scholar, J. B. Clark

University of Mississippi News

UM veterans and military services administrator first from Mississippi to be selected

July 21, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Poster 10, Mateo Oleas

Drug Discovery and Development Colloquium

No abstract provided.

Poster 9, Nicole Vita

Drug Discovery and Development Colloquium

No abstract provided.

Poster 6, Ashton Custer

Drug Discovery and Development Colloquium

No abstract provided.

Poster 2, Priyanka Samanta

Drug Discovery and Development Colloquium

No abstract provided.

Poster 4, John Gaydos

Drug Discovery and Development Colloquium

No abstract provided.

Poster 7, Rohini Dwivedi

Drug Discovery and Development Colloquium

No abstract provided.

Postdoctoral Oral Presentation, David Mery,Ph.D.

Drug Discovery and Development Colloquium

No abstract provided.

Th2/Th1 Cytokine Imbalance Is Associated With Higher Covid-19 Risk Mortality, Ana B. Pavel, Jacob W. Glickman, James R. Michels, Seunghee Kim-Schulze, Rachel L. Miller, Emma Guttman-Yassky

Faculty and Student Publications

A major component of COVID-19 severe respiratory syndrome is the patient’s immune response to the SARS-CoV-2 virus and the consequential multi-organ inflammatory response. Several studies suggested a potential role of CD4+ T cells in COVID-19 severe respiratory syndrome. We first hypothesized that there is a type 2 helper (Th2)/type 1 helper (Th1) imbalance in older age, male, asthma, smokers, and high ACE2 expression phenotype in the airway of non-infected patients. Next, we hypothesized that a Th2/Th1 imbalance may predict higher mortality in COVID-19 infected hospitalized patients with and without patient reported current asthma. We first analyzed publicly available gene expression …

Um, Community Partners Organize Bilingual Health Fair In Pontotoc, J. B. Clark

University of Mississippi News

Spanish-speaking community members invited to receive free screenings, health services

Poster 02, Ashley Nemec-Bakk

Drug Discovery and Development Colloquium

No abstract provided.

Poster 08, Seon Beom Kim

Drug Discovery and Development Colloquium

No abstract provided.

July 14, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Public Health Programs Welcome First Epidemiologist To Faculty, Staff Report

University of Mississippi News

Victoria Zigmont joins Department of Health, Exercise Science and Recreation Management

Phase-Specific And Lifetime Costs Of Multiple Myeloma Among Older Adults In The Us, Kaustuv Bhattacharya, John P. Bentley, Sujith Ramachandran, Yunhee Chang

Faculty and Student Publications

Importance: Health care costs associated with diagnosis and care among older adults with multiple myeloma (MM) are substantial, with cost of care and the factors involved differing across various phases of the disease care continuum, yet little is known about cost of care attributable to MM from a Medicare perspective. Objective: To estimate incremental phase-specific and lifetime costs and cost drivers among older adults with MM enrolled in fee-for-service Medicare. Design, Setting, and Participants: A retrospective cohort study was conducted using population-based registry data from the 2007-2015 Surveillance, Epidemiology, and End Results database linked with 2006-2016 Medicare administrative claims data. …

North Mississippi Vista Project Seeks Applicants, J. B. Clark

University of Mississippi News

Project places members in full-time community service positions

July 7, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Social Work Student Turns Tragedy Into Advocacy, Sarah Sapp

University of Mississippi News

Robin Minyard uses internship experience to prepare for role in counseling

Alumnus Examines Dangers Of Driving Under Influence Of Illicit Drugs, Sarah Sapp

University of Mississippi News

Graduate of master's program in criminal justice details public health and safety warnings

Identification Of Human Kinin-Forming Enzyme Inhibitors From Medicinal Herbs, Hassan Madkhali, Amer Tarawneh, Zulfiqar Ali, Hoang V. Le

Faculty and Student Publications

The goal of this study was to assess the pharmacological effects of black tea (Camellia sinensis var. assamica) water extract on human kinin-forming enzymes in vitro. Tea is a highly consumed beverage in the world. Factor XII (FXII, Hageman factor)-independent-and-dependent activation of prekallikrein to kallikrein leads to the liberation of bradykinin (BK) from high-molecular-weight kininogen (HK). The excessive BK production causes vascular endothelial and nonvascular smooth muscle cell permeability, leading to angioedema. The prevalence of angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema appears to be through BK. Both histamine and BK are potent inflammatory mediators. However, the treatments for histamine-mediated angioedema are …

Structure–Activity Relationships Of The Antimalarial Agent Artemisinin 10. Synthesis And Antimalarial Activity Of Enantiomers Of Rac-5Β-Hydroxy-D-Secoartemisinin And Analogs: Implications Regarding The Mechanism Of Action, Mohamed Jahan, Francisco Leon, Frank R. Fronczek, Khaled M. Elokely

Faculty and Student Publications

An efficient synthesis of rac-6-desmethyl-5β–hydroxy-D-secoartemisinin 2, a tricyclic analog of R-(+)-artemisinin 1, was accomplished and the racemate was resolved into the (+)-2b and (−)-2a enantiomers via their Mosher Ester diastereomers. Antimalarial activity resided with only the artemisinin-like enantiomer R-(−)-2a. Several new compounds 9–16, 19a, 19b, 22 and 29 were synthesized from rac-2 but the C-5 secondary hydroxyl group was surprisingly unreactive. For example, the formation of carbamates and Mitsunobu reactions were unsuccessful. In order to assess the unusual reactivity of 2, a single crystal X-ray crystallographic analysis revealed a close intramolecular hydrogen bond from the C-5 alcohol to the oxepane …