Digital Commons Network^™

New Mobile Safety App Use Encouraged For Um Students, Employees, Edwin B. Smith

University of Mississippi News

Everbridge provides emergency communications, COVID-19 updates, live bus routes and more

Incident Light And Morphology Determine Coral Productivity Along A Shallow To Mesophotic Depth Gradient, Michael P. Lesser, Marc Slattery, Curtis D. Mobley

Faculty and Student Publications

While the effects of irradiance on coral productivity are well known, corals along a shallow to mesophotic depth gradient (10–100 m) experience incident irradiances determined by the optical properties of the water column, coral morphology, and reef topography. Modeling of productivity (i.e., carbon fixation) using empirical data shows that hemispherical colonies photosynthetically fix significantly greater amounts of carbon across all depths, and throughout the day, compared with plating and branching morphologies. In addition, topography (i.e., substrate angle) further influences the rate of productivity of corals but does not change the hierarchy of coral morphologies relative to productivity. The differences in …

Computationally Assisted Lead Optimization Of Novel Potent And Selective Mao-B Inhibitors, Vedanjali Gogineni, Manal A. Nael, Narayan D. Chaurasiya, Khaled M. Elokely

Faculty and Student Publications

A series of dietary flavonoid acacetin 7-O-methyl ether derivatives were computationally designed aiming to improve the selectivity and potency profiles against monoamine oxidase (MAO) B. The designed compounds were evaluated for their potential to inhibit human MAO-A and-B. Compounds 1c, 2c, 3c, and 4c were the most potent with a Ki of 37 to 68 nM against MAO-B. Compounds 1c–4c displayed more than a thousand-fold selectivity index towards MAO-B compared with MAO-A. Moreover, compounds 1c and 2c showed reversible inhibition of MAO-B. These results provide a basis for further studies on the potential application of these modified flavonoids for the …

Sequentialdynamics Of Stearoyl-Coa Desaturase-1(Scd1)/Ligand Binding And Unbinding Mechanism: A Computational Study, Anna B. Petroff, Rebecca L. Weir, Charles R. Yates, Joseph D. Ng

Faculty and Student Publications

Stearoyl-CoA desaturase-1 (SCD1 or delta-9 desaturase, D9D) is a key metabolic protein that modulates cellular inflammation and stress, but overactivity of SCD1 is associated with diseases, including cancer and metabolic syndrome. This transmembrane endoplasmic reticulum protein converts saturated fatty acids into monounsaturated fatty acids, primarily stearoyl-CoA into oleoyl- CoA, which are critical products for energy metabolism and membrane composition. The present computational molecular dynamics study characterizes the molecular dynamics of SCD1 with substrate, product, and as an apoprotein. The modeling of SCD1:fatty acid interactions suggests that: (1) SCD1:CoA moiety interactions open the substrate-binding tunnel, (2) SCD1 stabilizes a substrate conformation …

Preparation And In Vitro/In Vivo Evaluation Of Orally Disintegrating/Modified-Release Praziquantel Tablets, Xuemei Wen, Zhaoyou Deng, Yangfeng Xu, Guoqing Yan

Faculty and Student Publications

This study was designed to develop orally disintegrating/sustained-release praziquantel (PZQ) tablets using the hot-melt extrusion (HME) technique and direct compression, and subse-quently evaluate their release in in vitro and in vivo pharmacokinetics. For the extrusion process, hypromellose acetate succinate (HPMCAS)-LG was the carrier of pure PZQ, with a standard screw configuration used at an extrusion temperature of 140◦ C and a screw rotation speed of 100 rpm. Differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), powder X-ray diffraction (PXRD) and Fourier-transform infrared spectroscopy (FTIR) were performed to characterize the extru-date. Orally disintegrating/sustained-release praziquantel tablets (PZQ ODSRTs) were prepared by direct compression …

Missy, Issue 1 (2021), Greg Parker

Missy: LGBTQ+ Literary Magazine

• Managing Editor: Greg Parker
• Associate Editors: Grace Marion, Michael Martella
• Outreach Coordinator: Emily Stewart
• Art Editor: Liz Parks
• Faculty Advisor: Tyler Gillespie

Structural And Kinetic Analyses Of Holothurian Sulfated Glycans Suggest Potential Treatment For Sars-Cov-2 Infection, Rohini Dwivedi, Priyanka Samanta, Poonam Sharma, Fuming Zhang

Faculty and Student Publications

Certain sulfated glycans, including those from marine sources, can show potential effects against SARS-CoV-2. Here, a new fucosylated chondroitin sulfate (FucCS) from the sea cucumber Pentacta pygmaea (PpFucCS) (MW ∼10.60 kDa) was isolated and structurally characterized by NMR. PpFucCS is composed of {→3)-β-GalNAcX-(1→4)-β-GlcA-[(3→1)Y]- (1→}, where X = 4S (80%), 6S (10%) or nonsulfated (10%), Y = α- Fuc2,4S (40%), α-Fuc2,4S-(1→4)-α-Fuc (30%), or α-Fuc4S (30%), and S = SO3-. The anti-SARS-CoV-2 activity of PpFucCS and those of the FucCS and sulfated fucan isolated from Isostichopus badionotus (IbFucCS and IbSF) were compared with that of heparin. IC50 values demonstrated the activity of …

Are Rural And Small Community Aerated Wastewater Stabilization Ponds A Neglected Source Of Microplastic Pollution?, Zhiqiang Gao, James V. Cizdziel, Kendall Wontor, Haitao Lu

Faculty and Student Publications

Wastewater treatment systems collect and treat sewage that includes microplastics (MPs). However, we are not aware of any studies on the occurrence and distribution of MPs in wastewater stabilization ponds (WSPs), which serve small communities worldwide. Here, we characterized MPs (~45 µm–5 mm) in an aerated WSP serving ~500 houses and an adjacent lake. Putative MPs were most abundant in duckweed (Lemna minor) and sludge (75 ± 22 and 12.8 ± 3.1 particles/g, respectively: ±1 standard deviation (SD), n = 6, dry weight). In the water, average concentrations (particles/L ± 1 SD, n = 6) were highest in the pond …

Pharmacy Matters - October 2021, University Of Mississippi. School Of Pharmacy

Pharmacy Matters Newsletters

Featured stories: "Pharmacy Graduate Students Win AAPS Student Chapter Award," "Stellar Student: Hyllore Imeri," "Pharmacology Graduate Student Striving for Excellence"

Southern Register. 2021.3 (Fall 2021), University Of Mississippi. Center For The Study Of Southern Culture

Southern Register

No abstract provided.

Math 671: Statistical Method I, Dao Nguyen

GMAS Course Syllabi

No abstract provided.

Ummc Research Breaks Funding Record, Karen Bascom

University of Mississippi News

Medical Center researchers tackling problems from cardiovascular health to COVID-19

Pharmacology Graduate Student Striving For Excellence, Patrick Smith

University of Mississippi News

Salahuddin Mohammed seeks to inspire future students through his work

Life And Health Insurance Entities, October 1, 2021; Audit And Accounting Guide, American Institute Of Certified Public Accountants (Aicpa)

Industry Guides (AAGs), Risk Alerts, and Checklists

No abstract provided.

The Use Of Dialectical Behavioral Therapy (Dbt) Techniques Creatively In The Treatment Of Perinatal Mood And Anxiety Disorders, Rosanne Nunnery, Missy Fauser, Elizabeth Hatchuel, Mary Jones

Journal of Counseling Research and Practice

Perinatal Mood and Anxiety Disorders (PMADs) is a serious condition impacting up to 21 percent of woman after the birth of a child (Byrnes, 2018). Jane, a 32-year-old female presented for treatment for anxiety, depression and mood disturbance (5th ed.; DSM-5; American Psychiatric Association, 2013) and in need of feeling more connected to her baby and her life. The use of creative techniques including mindfulness, distress tolerance activity, emotion regulation, and interpersonal skills (Linehan, 2015, 2016) were implemented. The use of these skills can be added to the repertoire of practice of a mental health counselor working with clients with …

Counseling Adolescents Aging Out Of Foster Care: A Neglected And Underserved Population, Taylor Tertocha-Ubelhor, Bryan R. Russ

Journal of Counseling Research and Practice

The high prevalence of youth aging out of the foster care system and the numerous poor outcomes they experience during the transition to emerging adulthood has been well documented. Although addressing the complex needs and concerns of this distinct population can be difficult, mental health counselors maintain the philosophical tenants and training strengths necessary to successfully serve youth aging out of foster care. This article aims to provide counselors with the historical context, developmental framework, and specific challenges needed to better understand this population, as well as suggested counseling implications to address their unique needs by reviewing relevant literature.

On Seeking Help: Social Reactions Experienced By Sexual Violence Survivors In The Indian Diaspora, Bagmi Das

Journal of Counseling Research and Practice

Sexual violence trauma counseling should be informed by the intersections of a survivor’s identity. This research focused on the social reactions experienced by survivors of sexual violence from the Indian diaspora. This study used quantitative survey research methods and correlational analysis as well as descriptive statistics to understand the social reactions that survivors received from informal supports and formal supports. Significant results, implications for counselors, and future research recommendations are discussed.

Full Issue, Mississippi Counseling Association

Journal of Counseling Research and Practice

No abstract provided.

Former Marine Tackles Ways To Improve Juvenile Justice, Staff Report

University of Mississippi News

William Agudelo examines problems of youth detention for graduate degree in criminal justice

September 30, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Issue 379: September 30-October 14, 2021, The Local Voice

The Local Voice

No abstract provided.

Daily Digest - Wednesday, September 29, 2021 Covid-19 Updates, University Of Mississippi

COVID-19 Website Archives

Campus Update Daily Digest for Wednesday, September 29, 2021

University Earns 'Tree Campus' Distinction, Mitchell Diggs

University of Mississippi News

Honor recognizes UM efforts to nurture green spaces on campus, promote conservation

Student Pharmacists Providing Flu Shots To Community, Whitney Tarpy

University of Mississippi News

Operation Immunization raises vaccine awareness and access

Gift Honors Family's Legacy Of Practicing Law, Bill Dabney

University of Mississippi News

UM alumnus Doug Wright gives back to law school, creates scholarship

September 23, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Newsletter, September 2021, Cedar Oaks Guild

Cedar Oaks Guild Newsletter

No abstract provided.

Supporting Nursing Education, Bill Dabney

University of Mississippi News

No abstract provided.

Issue 378: September 16-30, 2021, The Local Voice

The Local Voice

No abstract provided.

September 16, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.