Digital Commons Network^™

Diffusion Of Ionic Liquid-Modified Polymer Nanoparticles Through Nasal Mucus, Mary Vanlandingham

Honors Theses

Mucosal barriers are a natural defense system for preventing the entry of foreign objects into the body; however, they pose as obstacles for effective drug delivery. Coated polymer nanoparticles have been proven to possess improved rates of diffusion across mucus compared to their uncoated, or bare, counterparts. When choline-based ionic liquids (ILs) are introduced to an aqueous system, their dissociation leads to an increase in solution conductivity which ultimately reduces the viscosity of mucus without significantly affecting its structure. Additionally, ILs are highly tunable, so they work well in a range of pHs and conductivities, making ILs an ideal choice …

Un País Invertido: The Current Immigration Regime Of Colombia, Magdalena Hendrickson

Honors Theses

Throughout its turbulent history, Colombia has seen drastic changes in structure and administration. From military coups to shaky coalitions, the country’s infamous instability has long forced its citizens to find better prospects elsewhere. However, with the rise of the Maduro administration in Venezuela, Colombia faced a massive new flow of migrants and was forced to rectify current circumstances without properly addressing its internal issues beforehand. Despite its historical status as a nation of emigrants, Colombia marks a new norm for the rest of the globe. As new issues like climate change and increased armed conflict grow worldwide, countries on the …

Sleep Duration Is Associated With Caudate Volume And Executive Function, Nicole Jones

Honors Theses

The ineligible role of the caudate nucleus in sleep has been implicated throughout multiple scientific studies. Previous literature has shown that greater caudate volume is associated with longer habitual sleep duration in older adults- ranging from 55 years of age and up. However, the association between sleep duration and caudate volume remains unknown in the younger population. In this study, we examined the caudate volume in youth to older adults (10 to 85 years old) with a greater sample size (N=464) to increase statistical power. The volumetric size of the caudate nucleus showed significantly positive association with habitual sleep duration, …

Medical Marijuana In Mississippi: A Journalistic View Of Physician Opinions And Patient Education, Michael Pitts

Honors Theses

Medical Marijuana in Mississippi: A Journalistic View of Physician Opinions and Patient Education is an in-depth investigative journalism project examining aspects of the Mississippi Medical Cannabis Program. Specific areas of interest were Mississippi physician opinions on the use medical marijuana and their views on the application of the state’s program as well as an examination into how patients are receiving education on medical marijuana. This project involved interviews of healthcare providers, dispensary staff, and patients, in addition to background research that was used to formulate interview questions, determine areas of interest and add necessary context. This project occurred during the …

A Synthetic Approach To The Optimization Of Silicon-Rosindolizine Swir Fluorophores, Timothy Lewis

Honors Theses

Fluorophores emitting within the near-infrared (700 – 1000 nm) or shortwave-infrared (1000 – 1700 nm) regions of the electromagnetic spectrum are of particular interest for their potential to supplement or even outright replace commonly used biological imaging techniques, such as magnetic resonance imaging and computed tomography scanning. Various characteristics make these molecules particularly appealing to researchers, such as their ease of synthetic tunability, generally low toxicity, and high solubility in biological media in comparison to other NIR- and SWIR-emissive fluorophores. Different molecular skeletons have been examined for use as the core of these imaging agents, such as squaraine, cyanine, and …

Development Of An Immunoblot Assay To Detect Antibodies To Sars-Cov-2 Spike And Nucleocapsid Antigens In Serum Of Covid-19 Patients, Christian Hollis

Honors Theses

The coronavirus disease (COVID-19) has created one of the most world-halting events in recent world history. Its effects have reached every corner of the globe and manifested problems within each country’s healthcare and social systems. During the pandemic, many researchers have searched to develop a more robust understanding of the novel virus’s genetic and structural material. In year three since the emergence of COVID-19, these researchers hope to implement new advancements in testing and detection for the presence of the virus.

This thesis intends to produce evidence for the reliability of COVID-19 antibody tests using immunoblot assay detection. These tests …

The Effects Of Aloe Vera On The Human Gut Microbiome, Samantha Leon

Honors Theses

The human gut microbiome is a diverse community of bacteria influenced by multiple factors including host age, geographical location, and diet. This study observed the effects of aloe vera juice on the human gut microbiome. Fecal samples were taken every two weeks over a period of one year; the subject consumed aloe vera juice in alternating cycles of consumption “on” and abstaining “off” with each cycle lasting for eight weeks. The bacterial community in each sample was characterized using 16S rRNA gene sequencing. Sequences were identified and their relative abundances were used to look for patterns distinguishing “on” and “off” …

Predictors Of Future Physician Practice Location, Allegra Latimer

Honors Theses

Healthcare disparities exist throughout the United States. While Mississippi does not stand alone in the maldistribution of physicians and medical practices across the state, it does exist as a state that has been historically medically underserved. According to data collected by The County Health Rankings Model developed by the University of Wisconsin Population Health Institute, in 2019, the ratio of population to primary care physicians in Mississippi was 1860:1. This is nearly 30% higher in disparity than the national average. It is also important to note that of Mississippi’s 82 counties, 79.3% are considered rural with the majority of physicians …

Structural Integrity And Stability Of Dna In Ionic Liquid And Near-Infrared Indolizine Squaraine Dye, Ember Yeji Suh

Honors Theses

Luminol, the most common presumptive test for blood at a crime scene, has multiple issues, such as false positive results with chemical agents, no luminescence due to “active oxygen” cleaning agents on bloodstains, and inability to penetrate textile materials. A combination of indolizine squaraine dye and ionic liquid (IL), or Dye Enhanced Textile Emission for Crime Tracking (DETECT), have shown potential to address these issues. The purpose of this study was to assess the binding mechanism of CG (1:1) and SO₃SQ dye to HSA and how the mechanism can explain the W214 fluorescence quenching effect and to determine …

Associations Between Tiktok Use, Mental Health, And Body Image Among College Students, Alexz Carpenter

Honors Theses

Background. Social media use continues to increase globally, and there is a large field of research examining the relationships between social media use with anxiety, depression, and body image. College-aged students are particularly vulnerable to these associations because they are at a unique developmental point of their life. College-aged students also use social media more frequently than almost any other age group, which may put them at increased risk for negative mental health and body image outcomes related to their social media use. TikTok is a relatively new social media app that has exponentially risen in popularity, especially among younger …

Botulinum Toxin For Abductor Type Spasmodic Dysphonia: A Systematic Review, Keyona Sutton

Honors Theses

A systematic review was conducted to show that BTX (Botulinum Toxin) is the most effective treatment for Abductor Spasmodic Dysphonia (ABSD). There were a total of 117 records screened for inclusion in this review. After the initial screening, there were seven successive rounds of screening for eligibility. This process produced a total of three eligible records that met the following conditions: patients presented with spastic abduction, electromyography BTX type A injection into the posterior cricoarytenoid muscle, and measurement of results with acoustic dimensions. After surveying all eligible studies, it was concluded that BTX is an effective treatment for ABSD. Every …

Gender Disparities Present Within The Legal Profession, Olivia M. Sanders

Honors Theses

This thesis investigates the problem of gender disparities present within the legal profession in order to discover their causes and ways to mitigate them. Currently, there are a variety of gender disparities in the legal profession. Women are paid less than their male counterparts, are exposed to sexual harassment and violence more often, and receive fewer leadership opportunities, to name just a few of these disparities. While these disparities are documented in larger firms, little data exists on the extent of such issues in smaller firms, especially in the southeastern United States. Accordingly, I interviewed eight individuals with their juris …

Aging An Ancient Maya Population From Actuncan, Belize Using Dental X-Rays, Kaitlyn Nicole Cash

Honors Theses

My goal is to determine an accurate age at death estimation of an ancient Maya population from the archaeological site of Actuncan, Belize. This was done by measuring the lengths of the coronal pulp cavities in the individuals’ teeth. I used X-Ray images to measure the coronal pulp cavities of the teeth and estimated age using multiple regression formulae for premolars, molars, and incisors to make age estimations. The formulae came from two studies, Ikeda et al. (1985) and Drusini (2008), that form the basis of my research. Ikeda et al. (1985) was the first to use this aging method, …

Hungry For Student Food Security: A Comparative Analysis Of University Food Pantry Policies, Anastasia Jones-Burdick

Honors Theses

This undergraduate research thesis aims to explore the relationship between public institutions of higher education and the operational policies of their university food pantries. The increasing rates of nontraditional students entering public universities correlate to an increasing population of students facing food insecurity, placing strain on institutional interventions, especially university food pantries (National Center for Education Statistics, 2015; Nazmi et al., 2019, p.2). This research conducted a qualitative comparative case analysis of university food pantry policies and semistructured interviews with pantry informants through a USDA-adapted evaluative framework to understand the evolution of public universities’ interventions (Barale et al., 2017). The …

Investigating Reactivity Of Artificial Copper Peptides With Small Molecules, Allyson Bryant

Honors Theses

The design of artificial enzymes has been a topic of significant interest in the field of biochemistry, as they can provide new opportunities for catalytic processes and drug development. De novo protein design has emerged as a promising approach to create such enzymes, and the study of metalloproteins, particularly copper-binding peptides, has become a focus of this research. This thesis investigates the reactivity of a mutated copper-binding peptide, I5A-3SCC, with oxygen and its implications in the development of artificial enzymes.

The parent peptide, 3SCC, was mutated by replacing Isoleucine residues with smaller Alanine side chains, which was hypothesized to enhance …

Analyzing The Unique Role Of Repetitive Negative Thinking On Insomnia In College Students, Lara Fair

Honors Theses

Repetitive negative thinking is a transdiagnostic construct that conceptually covers worry and rumination, which are strongly associated with anxiety and depression. Worry is typically future oriented, whereas rumination is past oriented. RNT has been posited as a causal and maintaining factor for multiple disorders, including generalized anxiety disorder, depression, and insomnia. The current study aimed to further understand the contribution of RNT in insomnia symptoms, after controlling for anxiety and depression. A self-report battery measuring anxiety, depression, RNT and insomnia was administered to 101 college students. In this sample, 52% of participants endorsed clinical levels of insomnia. Bivariate correlations found …

Key Barriers To University-Enrolled Student Parents Enhanced By The Covid-19 Pandemic, Khadeejah Franklin, Alexa Saval

Honors Theses

Student parents, both undergraduate and graduate, already face the difficult task of balancing their studies and raising children. The COVID-19 pandemic enhanced already present issues student parents face, such as virtual-schooling, daycare costs and closings, staying home with sick children, and potentially not having a local support system, among others. Further, students who are performing laboratory research to fulfill their STEM educational requirements had their
research progress come to a halt when the country locked down. This study aims to identify the struggles student parents faced prior to the COVID-19 pandemic, what issues the pandemic exacerbated, and what new problems …

Women In Dentistry At The University Of Mississippi: Increasing The Confidence And Skills Of Future Women Dentists, Lakin Cramer

Honors Theses

Women in Dentistry became a registered student organization in February 2022. The purpose of the organization is to encourage and promote the professional and personal success of women in dentistry on the University of Mississippi Oxford campus. The historical and current literature of Women in Dentistry serve to provide a framework for the importance of uplifting women as they prepare for a career in dentistry. During my time as Founder and President of Women in Dentistry, my goal was to establish the organization, provide mentorship to prospective female dental school applicants, and increase the confidence and skills of future women …

The Associations Between Adolescent Motives For Social Media Use With Body Dysmorphia, Eating Disorder, And Anxiety And Depression Symptoms, Kaylan Melvin

Honors Theses

Adolescents spend a large amount of time on social media sites. This is notable, as adolescence is a crucial time for body image development. Additionally, recent findings suggest that using image-oriented social media sites, such as Facebook and Instagram, is associated with more body dissatisfaction and disordered eating. Among previous studies, certain social media motivations have been found to have an association with poor body satisfaction and well-being in adolescents. To our knowledge, no studies have directly examined the association between social media motivations and eating disorder, body dysmorphic disorder, and anxiety and depression symptoms in adolescents. The current study …

An Examination Of Financial Accounting Through Case Studies And Discussion, Andrew Meyer

Honors Theses

This thesis is a collection of eleven case studies completed over the course of the 2021-2022 academic year in the Patterson School of Accountancy in the ACCY 420 course, under the direction of Dr. Victoria Dickinson. The cases cover a broad array of concepts within the field of accounting. A few examples of topics include the impact of the September 11, 2001, terrorist attacks on business in America, the impact of the COVID-19 pandemic on the financials of Pfizer Inc., and an interview with a successful entrepreneur. From Case 6 on, the thesis is comprised of an analysis of the …

The Interhemispheric Auditory Tract Connectivity And Autism Spectrum Disorder, Josie Long

Honors Theses

Individuals with autism spectrum disorder (ASD) can have abnormal responses and hypersensitivity to sounds (Haesen et al., 2011). ASD is also related to inattentive, hyperactive, and impulsive behaviors (Bradley & Isaacs, 2006). One study by Stansberry et al. (2022) found that a higher fractional anisotropy (FA) of interhemispheric auditory white matter is associated with higher impulsivity. Our study examined the interhemispheric auditory tract (IAT) to determine whether it is impacted by ASD. We used diffusion tensor imaging (DTI) data from Autism Brain Imaging Data Exchange utilizing two datasets so that we could replicate primary findings. We first isolated the IAT …

An Analysis Of The Sensory Characteristics And Microbial Constituents Of Kefir, Katherine Quay Robinson

Honors Theses

Kefir is a fermented beverage produced using sugar water or milk, kefir grains, either water kefir grains or milk kefir grains, respectively, and microbial aggregates consisting of diverse bacteria and yeasts. As kefir and fermented beverages in general are increasing in popularity, research related to optimal sensory characteristics and consumer-approval is vital. Desirable sensory characteristics for kefir beverages include low sour taste/aroma, high sweetness, carbonation, and high viscosity (Surja et al., 2019; Margareth et al., 2020). Production methods of kefir can alter sensory characteristics, but sensory characteristics are likely strongly influenced by the microbial composition of the grains/product. Thus, an …

Dextromethorphan/Quinidine For The Pseudobulbar Affect In Neurological Disorders And Injuries: Systematic Review And Meta-Analysis, Magnolia Livingston

Honors Theses

AVP-923, commonly known as Nuedexta or Zenvia, is a drug that has recently been suggested as a potential treatment for Pseudobulbar Affect in patients affected by different neurological disorders and injuries. Studies have been done to examine the effectiveness of AVP-923 on PBA, but the results of these studies don’t seem to be comparable. The goal of this meta-analysis is to assess the efficacy and safety of AVP-923. 781 individuals from six trials were included in the analysis. The analysis's findings revealed that AVP-923 considerably lowered the Center for Neurological Study Lability Scale (CNS-LS) scores and the frequency and severity …

The Effects Of Acute Exercise Intensity On Memory: State-Dependent Learning, Lauren E. Fuglaar, Rylie S. Mangold, Sierra N. Petty

Honors Theses

The Encoding-Specificity Paradigm states that memory recall will be enhanced when contextual factors are congruent between memory encoding and memory retrieval (i.e., state-dependent learning). However, minimal research has evaluated this paradigm in the exercise domain. The purpose of this study was to evaluate the effects of acute exercise intensity on memory while considering these potential state-dependent effects. Forty-eight university students completed a within-subject experiment involving seven laboratory visits, during which they encoded a list of 15 words and were subsequently asked to free-recall as many of these words as possible. The encoding and retrieval phases were matched or mismatched by …

Identification And Assessment Of Fixed Versus Growth Mindsets In Human And Anatomy Physiology Undergraduate Students, Jayanti Shukla

Honors Theses

Fixed mindsets and growth mindsets are present in individual’s attitudes, affecting their motivations to complete responsibilities or overcome challenges. In this study, we aim to identify and assess the mindsets of undergraduate students partaking in the Human Anatomy and Physiology (HAP) undergraduate course at the University of Mississippi, the gateway course being well-known for its difficulty and being described as “daunting” to many allied-health majors. By utilizing Carol Dweck’s growth mindset model, we are interested in determining whether students possess a “fixed” mindset versus a “growth” mindset, in conjunction to assessing their classroom performance correlating with that demonstrated mindset. An …

Historical Archaeology At The Chalmers Institute, Mississippi's First University, Antosia Briggs

Honors Theses

This study presents a basic description and analysis of the artifacts collected from the 2015 archaeological excavation conducted in Holly Springs, Mississippi at the Chalmers Institute site. The thesis includes history and background on Holly Springs as a city to orient the reader. This text also includes information regarding the program, Preserve Marshall County, as their work regarding the building and site ties directly into the ability of the student archaeologists being able to excavate in 2015 as well as the future of the building. This study analyzes the artifacts found based on the frameworks of the archaeology of institutional …

Photocatalyzed Hydrogen Evolution Using Nickel-Bound Metallothionein Protein, Windfield Swetman

Honors Theses

The continued burning of fossil fuels is not only a cause of increasing deterioration of the environment but also a financially unsustainable source of energy. Advances in energy production must be investigated to avoid the long-term effects of this current main source of energy. One of the avenues being explored is the use of metalloenzymes to catalyze hydrogen evolution via water splitting that occurs during the reductive half of artificial photosynthesis. Metalloenzyme catalysts with a single Ni(Cys)₄ active site have been previously studied, and this study explores the possibility of increasing hydrogen production by using metalloenzyme catalysts with multiple …

University Of Mississippi 170th Commencement, 2023, University Of Mississippi, Glenn F. Boyce, Noel E. Wilkin, Stephanie Hickman

Commencement Programs

No abstract provided.

Financial Accounting Case Studies, John A. Batson Jr

Honors Theses

This thesis was completed in the 2021-2022 academic year and is comprised of eleven accounting case studies. The topics from these cases vary widely and are not strictly focused on accounting. Examples of this includes cases done on the twenty-year anniversary of 9/11, the ramifications of COVID-19 on Pfizer, and having to interview a local business owner. We also completed cases concerning the city we wanted to intern in as well as an excel certification course. Following the conclusion of case 5, me and several other honors students worked together to complete the next six cases which involved analyzing International …

An Analysis Of Accounting Concepts Through Case Studies, Molly Medling

Honors Theses

This thesis aims to provide a holistic picture of the accounting profession through various topics in the field. Divided into case studies, each case examines a particular accounting issue or concept through research and analysis. These cases range from an examination of the events of 9/11 through the lens of the accounting profession to a multiple-case analysis of International Paper Company’s financial position and future actions. Several online articles, financial reports, and accounting courses were used to inform the information included in this thesis. These sources were not only used to provide an analysis of accounting concepts, but also to …