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Open Meeting Agenda, February 12, 2019, New Orleans, La, American Institute Of Certified Public Accountants. Professional Ethics Division. Professional Ethics Executive Committee Feb 2019

Open Meeting Agenda, February 12, 2019, New Orleans, La, American Institute Of Certified Public Accountants. Professional Ethics Division. Professional Ethics Executive Committee

Association Sections, Divisions, Boards, Teams

No abstract provided.


February 11, 2019, The Daily Mississippian Feb 2019

February 11, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


February 8, 2019, The Daily Mississippian Feb 2019

February 8, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


Issue 320: February 7-21, 2019, The Local Voice Feb 2019

Issue 320: February 7-21, 2019, The Local Voice

The Local Voice

No abstract provided.


February 7, 2019, The Daily Mississippian Feb 2019

February 7, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


Doxorubicin Loaded Magnesium Oxide Nanoflakes As Ph Dependent Carriers For Simultaneous Treatment Of Cancer And Hypomagnesemia, Tharindu A. Ranathunge, D. G.G.P. Karunaratne, R. M.G. Rajapakse, Davita L. Watkins Feb 2019

Doxorubicin Loaded Magnesium Oxide Nanoflakes As Ph Dependent Carriers For Simultaneous Treatment Of Cancer And Hypomagnesemia, Tharindu A. Ranathunge, D. G.G.P. Karunaratne, R. M.G. Rajapakse, Davita L. Watkins

Faculty and Student Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Doxorubicin (DOX) is an anticancer drug commonly used in treating cancer; however, it has severe cytotoxicity effects. To overcome both the adverse effects of the drug and mineral deficiency (i.e., hypomagnesemia) experienced by cancer patients, we have developed magnesium oxide (MgO) nanoflakes as drug carriers and loaded them with DOX for use as a targeted drug delivery (TDD) system for potential application in cancer therapy. The synthesis employed herein affords pure, highly porous MgO nanoparticles that are void of the potentially harmful metal contaminants often discussed in the literature. Purposed for …


February 6, 2019, The Daily Mississippian Feb 2019

February 6, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


February 4, 2019, The Daily Mississippian Feb 2019

February 4, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


3d-Printed Isoniazid Tablets For The Treatment And Prevention Of Tuberculosis—Personalized Dosing And Drug Release, Heidi Öblom, Jiaxiang Zhang, Manjeet Pimparade, Isabell Speer, Maren Preis, Michael Repka, Niklas Sandler Feb 2019

3d-Printed Isoniazid Tablets For The Treatment And Prevention Of Tuberculosis—Personalized Dosing And Drug Release, Heidi Öblom, Jiaxiang Zhang, Manjeet Pimparade, Isabell Speer, Maren Preis, Michael Repka, Niklas Sandler

Faculty and Student Publications

© 2019 by the authors. Although 4-O-Methylhonokiol (MH) effects on neuronal and immune cells have been established, it is still unclear whether MH can cause a change in the structure and function of the cardiovascular system. The overarching goal of this study was to evaluate the effects of MH, isolated from Magnolia grandiflora, on the development of the heart and vasculature in a Japanese medaka model in vivo to predict human health risks. We analyzed the toxicity of MH in different life-stages of medaka embryos. MH uptake into medaka embryos was quantified. The LC50 of two different exposure windows (stages …


Association Between Perceived Physical Activity And Cognitive Function In Older Adults, Paul D. Loprinzi, Emily Frith Feb 2019

Association Between Perceived Physical Activity And Cognitive Function In Older Adults, Paul D. Loprinzi, Emily Frith

Faculty and Student Publications

© The Author(s) 2018. There is irrefutable evidence that regular participation in physical activity is favorably associated with numerous positive health outcomes, including cognitive function. Emerging work suggests that perceived physical activity, independent of actual physical activity behavior, is inversely associated with mortality risk. In this study, we evaluate whether perceived physical activity, independent of actual physical activity, is associated with cognitive function, a robust indicator of mortality risk. Data from the cross-sectional 1999–2002 National Health and Nutrition Examination Survey were employed (N = 2352; 60+ years of age). Actual physical activity was assessed via a validated survey. Perceived physical …


February 1, 2019, The Daily Mississippian Feb 2019

February 1, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


January 31, 2019, The Daily Mississippian Jan 2019

January 31, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


Law Professor Assists Mississippi's Sentencing Disparity Task Force, Christina Steube Jan 2019

Law Professor Assists Mississippi's Sentencing Disparity Task Force, Christina Steube

University of Mississippi News

Phillip Broadhead presented data for task force, legislators to review while considering reforms


January 30, 2019, The Daily Mississippian Jan 2019

January 30, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


January 28, 2019, The Daily Mississippian Jan 2019

January 28, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


January 25, 2019, The Daily Mississippian Jan 2019

January 25, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


January 24, 2019, The Daily Mississippian Jan 2019

January 24, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


Issue 319: January 24-February 7, 2019, The Local Voice Jan 2019

Issue 319: January 24-February 7, 2019, The Local Voice

The Local Voice

No abstract provided.


January 23, 2019, The Daily Mississippian Jan 2019

January 23, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


Pharmacy School Gets A Boost From Former Arkansas Legislator, Bill Dabney, Sydney Slotkin Dupriest Jan 2019

Pharmacy School Gets A Boost From Former Arkansas Legislator, Bill Dabney, Sydney Slotkin Dupriest

University of Mississippi News

No abstract provided.


Issue 318: January 10-24, 2019, The Local Voice Jan 2019

Issue 318: January 10-24, 2019, The Local Voice

The Local Voice

No abstract provided.


Development Of A Clinical Teaching Evaluation And Feedback Tool For Faculty, Erin Dehon, Ellen Robertson, Marie Barnard, Jonah Gunalda, Michael Puskarich Jan 2019

Development Of A Clinical Teaching Evaluation And Feedback Tool For Faculty, Erin Dehon, Ellen Robertson, Marie Barnard, Jonah Gunalda, Michael Puskarich

Faculty and Student Publications

Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics. Sigma-2 receptors, recently identified as TMEM97, have been implicated in cancer and neurodegenerative disease. Structurally distinct sigma-2 receptor ligands induce cell death in tumor cells, linking sigma-2 receptors to apoptotic pathways. Recently, we reported that sigma-2 receptors can also stimulate glycolytic hallmarks, effects consistent with a prosurvival function and upregulation in cancer cells. Both apoptotic and metabolically stimulative effects were observed with compounds related to the canonical sigma-2 antagonist SN79. Here we investigate a series of 6-substituted SN79 analogs to assess the structural determinants governing these divergent effects. …


Identification And Characterization Of Key Chemical Constituents In Processed Gastrodia Elata Using Uhplc-Ms/Ms And Chemometric Methods, Xide Ye, Yanhong Wang, Jianping Zhao, Mei Wang, Bharathi Avula, Qiaozhen Peng, Hui Ouyang, Zhong Lingyun, Jinlian Zhang, Ikhlas A. Khan Jan 2019

Identification And Characterization Of Key Chemical Constituents In Processed Gastrodia Elata Using Uhplc-Ms/Ms And Chemometric Methods, Xide Ye, Yanhong Wang, Jianping Zhao, Mei Wang, Bharathi Avula, Qiaozhen Peng, Hui Ouyang, Zhong Lingyun, Jinlian Zhang, Ikhlas A. Khan

Faculty and Student Publications

© The Author(s) 2019. Background. Obesity is a major medical issue nationally, with rates continually increasing. In obese patients, minimal data exist for appropriate dosing of acyclovir to decrease the rates of nephrotoxicity. The purpose of this study was to determine the prevalence of and risk factors associated with acyclovir-induced nephrotoxicity. Methods. A retrospective case-control of patients who received intravenous acyclovir for >48 hours at University of Mississippi Medical Center over a 4-year period were evaluated to elucidate the prevalence of acyclovir-induced nephrotoxicity. Additionally, risk factors for the development of nephrotoxicity, including the effect of obesity and dosing strategy, were …


Phytochemical Screening Of Pulsatilla Species And Investigation Of Their Biological Activities, Grażyna Łaska, Aneta Sienkiewicz, Marcin Stocki, Jordan K. Zjawiony, Vimal Sharma, Andrzej Bajguz, Alicja Piotrowska-Niczyporuk, Melissa Jacob, Shabana Khan Jan 2019

Phytochemical Screening Of Pulsatilla Species And Investigation Of Their Biological Activities, Grażyna Łaska, Aneta Sienkiewicz, Marcin Stocki, Jordan K. Zjawiony, Vimal Sharma, Andrzej Bajguz, Alicja Piotrowska-Niczyporuk, Melissa Jacob, Shabana Khan

Faculty and Student Publications

© 2019, The Author(s). We previously demonstrated that extracts from Echinacea purpurea material varied substantially in their ability to activate macrophages in vitro and that this variation was due to differences in their content of bacterial components. The purpose of the current study was to identify soil conditions (organic matter, nitrogen, and moisture content) that alter the macrophage activation potential of E. purpurea and determine whether these changes in activity correspond to shifts in the plant-associated microbiome. Increased levels of soil organic matter significantly enhanced macrophage activation exhibited by the root extracts of E. purpurea (p < 0.0001). A change in soil organic matter content from 5.6% to 67.4% led to a 4.2-fold increase in the macrophage activation potential of extracts from E. purpurea. Bacterial communities also differed significantly between root materials cultivated in soils with different levels of organic matter (p < 0.001). These results indicate that the level of soil organic matter is an agricultural factor that can alter the bacterial microbiome, and thereby the activity, of E. purpurea roots. Since ingestion of bacterial preparation (e.g., probiotics) is reported to impact human health, it is likely that the medicinal value of Echinacea is influenced by cultivation conditions that alter its associated bacterial community.


Top-Down Etd-Ms Provides Unreliable Quantitation Of Methionine Oxidation, Surendar Tadi, Joshua S. Sharp Jan 2019

Top-Down Etd-Ms Provides Unreliable Quantitation Of Methionine Oxidation, Surendar Tadi, Joshua S. Sharp

Faculty and Student Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. The aim of this study was to evaluate the total phenolic and flavonoid content, and the in vitro antioxidant, anti-inflammatory, antibacterial, antifungal, antimalarial, cytotoxicity, and antiprotozoal activities of the Algerian plant Cytisus villosus Pourr. (Syn. Cytisus triflorus L’Hérit.). Additionally, the radioligand displacement affinity on opioid and cannabinoid receptors was assessed for the extracts and isolated pure compounds. The hydro alcoholic extract of the aerial part of C. villosus was partitioned with chloroform (CHCl3), ethyl acetate (EtOAc), and n-butanol (n-BuOH). The phenolic content of the C. villosus extracts was evaluated using a …


Impact Of Hydration Status On Electromyography And Ratings Of Perceived Exertion During The Vertical Jump, Paul T. Donahue, Samuel J. Wilson, Charles C. Williams, Melinda Valliant, John C. Garner Jan 2019

Impact Of Hydration Status On Electromyography And Ratings Of Perceived Exertion During The Vertical Jump, Paul T. Donahue, Samuel J. Wilson, Charles C. Williams, Melinda Valliant, John C. Garner

Faculty and Student Publications

Copyright (c) the author(s). This is an open access article under CC BY license (https://creativecommons.org/licenses/by/4.0/) Background: The vertical jumping task is commonly used to assess lower-body power output in athletic populations, in addition to being commonly used to during investigations of hydration and anaerobic performance. Changes in neuromuscular function during a hypohydrated state have been proposed as a potential mechanism to decreases in anaerobic performance. Objectives: The primary purpose of this investigation was to examine the impact of hydration state on electromyography during the vertical jumping task. Methods: Twenty recreationally trained males were tested in three hydration conditions (hypohydrated, euhydrated, …


Optimizing Mri Sequences And Images For Mri-Based Stereotactic Radiosurgery Treatment Planning, Somayeh Taghizadeh, Cecille Labuda, Claus Chunli Yang, Bart Morris, Madhava R. Kanakamedala, Srinivasan Vijayakumar, Roberto Rey-Dios, William N. Duggar, Edward Florez, Ali Fatemi Jan 2019

Optimizing Mri Sequences And Images For Mri-Based Stereotactic Radiosurgery Treatment Planning, Somayeh Taghizadeh, Cecille Labuda, Claus Chunli Yang, Bart Morris, Madhava R. Kanakamedala, Srinivasan Vijayakumar, Roberto Rey-Dios, William N. Duggar, Edward Florez, Ali Fatemi

Faculty and Student Publications

© 2018 Aim: Development of MRI sequences and processing methods for the production of images appropriate for direct use in stereotactic radiosurgery (SRS) treatment planning. Background: MRI is useful in SRS treatment planning, especially for patients with brain lesions or anatomical targets that are poorly distinguished by CT, but its use requires further refinement. This methodology seeks to optimize MRI sequences to generate distortion-free and clinically relevant MR images for MRI-only SRS treatment planning. Materials and methods: We used commercially available SRS MRI-guided radiotherapy phantoms and eight patients to optimize sequences for patient imaging. Workflow involved the choice of correct …


The Effects Of High-Intensity Interval Exercise And Hypoxia On Cognition In Sedentary Young Adults, Shengyan Sun, Paul D. Loprinzi, Hongwei Guan, Liye Zou, Zhaowei Kong, Yang Hu, Qingde Shi, Jinlei Nie Jan 2019

The Effects Of High-Intensity Interval Exercise And Hypoxia On Cognition In Sedentary Young Adults, Shengyan Sun, Paul D. Loprinzi, Hongwei Guan, Liye Zou, Zhaowei Kong, Yang Hu, Qingde Shi, Jinlei Nie

Faculty and Student Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Background and Objectives: Limited research has evaluated the effects of acute exercise on cognition under different conditions of inspired oxygenation. Thus, the purpose of this study was to examine the effects of high-intensity interval exercise (HIE) under normoxia (inspired fraction of oxygen (FIO2): 0.209) and moderate hypoxia (FIO2: 0.154) on cognitive function. Design: A single-blinded cross-over design was used to observe the main effects of exercise and oxygen level, and interaction effects on cognitive task performance. Methods: Twenty inactive adults (10 males and 10 females, 19–27 years old) performed a cognitive …


The Effects Of Acute Exercise Intensity On Episodic And False Memory Among Young Adult College Students, Emma K. Dilley, Liye Zou, Paul D. Loprinzi Jan 2019

The Effects Of Acute Exercise Intensity On Episodic And False Memory Among Young Adult College Students, Emma K. Dilley, Liye Zou, Paul D. Loprinzi

Faculty and Student Publications

© 2019 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License Background: Previous experimental work demonstrates that acute exercise may enhance episodic memory performance. However, limited research has examined the extent to which acute exercise influences false episodic memory production, and no studies, to date, have examined whether there is an intensity-specific effect of acute exercise on both true episodic and false episodic memories. Thus, the present experiment evaluated the effects of intensity-specific acute exercise on episodic memory and false episodic memory. Methods: A three-arm, parallel, between-group randomized controlled trial was …


Investigating Early Childhood Teachers’ Perceptions Of A Preschool Yoga Program, Kenya Wolff, Alicia Stapp Jan 2019

Investigating Early Childhood Teachers’ Perceptions Of A Preschool Yoga Program, Kenya Wolff, Alicia Stapp

Faculty and Student Publications

© The Author(s) 2019. Yoga for young children has become a growing area of interest in early childhood settings across the United States. Evidence suggests that yoga has the ability to improve young children’s physical development, executive functioning, self-regulation, and can aid in decreasing stress and anxiety. While the scope of research on yoga for young children has primarily focused on the experiences and outcomes of the children who participate, far less is known about the experiences and perceptions of teachers who have engaged in such programs with their students. This study utilized a qualitative case study to investigate teachers’ …