Digital Commons Network^™

Serine And Glutathione Biosynthesis In Breast Cancer Subclones That Preferentially Metastasize To Lung And Bone, Noah Thornton

Honors Theses

Metastatic breast cancers show distinct preferences to metastasize to lung and bone tissue. Transcriptomic analysis of lung-specific (LM) and bone-specific (BoM) subclones derived from the MDA-231 breast cancer line have identified differential expression of genes that may mediate this tissue-specific metastasis, but metabolic differences have not been systematically studied. If common metabolic phenotypes emerge in metastatic cancers having preferences for different organs, then such ‘metabolic plasticity’ may offer new therapeutic targets for treatment of specific metastases. Changes in glutathione (GSH) and serine synthesis may contribute to tissue-specific proliferation because of their roles in redox homeostasis, biosynthetic reactions including nucleotide synthesis, …

Examining Public Water Systems Servicing Schools And Childcare Facilities To Inform Policy: A Study Of Lead Exposure In The Mississippi Delta, William Farmer

Honors Theses

Abstract

This study was initiated with the intent of identifying elementary schools and childcare facilities in the Mississippi Delta with children ages 6 and under that may have public water systems (PWSs) with lead exceedances of 5 ppb. We also aimed to identify the existence, and further the availability, of information regarding which public schools and childcare facilities were serviced by which public water systems. Based on the results of this study, considerations related to Mississippi’s ability to comply with the 2020 Revisions of the Lead and Copper Rule requiring testing in all public schools were determined. Seven principal counties …

Association Of Trim Gene Variation And Lpdv Infection Patterns In Wild Turkeys, Bennett Fry

Honors Theses

Emerging infectious diseases pose a serious threat to various species throughout the globe, including humans. The lymphoproliferative disease virus (LPDV) in wild turkeys is an example of disease virus whose impact on its host requires additional study. Although the first description of lymphoproliferative disease came from outbreaks in domestic turkey flocks in Europe, it is now known that LPDV is widespread in wild turkey populations in North America. In an effort to understand what may affect an individual turkey’s susceptibility to this virus, variation in part of the anti-viral TRIM62 gene was investigated. DNA was extracted from hunter-collected, turkey blood …

Examining Bystander Blame In Rape And Sexual Assault, Katherine E. Purdom

Honors Theses

The present study investigated the effect of various factors on blame distribution in sexual violence cases. Participants (N = 378) were randomly assigned to either a rape (N = 187) or sexual assault (N = 190) condition and directed to read a scenario that varied only by the terminology indicated by the condition. Participants were provided two pre-filled slots labeled as the perpetrator and victim. Additionally, they were given two blank “free-response” options in which participants could assign blame and indicate a responsible party if they found it necessary. Data was gathered from the male (N = 163) and female …

Tablet Use And Social Skills In Autism Spectrum Disorder, Taylor Schwartz

Honors Theses

The use of computer tablets can be beneficial for communication deficits in Autism. Studies have shown that tablets can have positive effects on individuals with Autism Spectrum Disorder (ASD) who have trouble communicating and expressing emotions. A systematic review was conducted to examine if tablets helped people with ASD develop social skills and expression of emotion. A search was conducted through PubMed. From the initial search, 117 articles were found. Of these 117 articles, 10 met the criteria for review along with 2 additional articles found from an additional source. These 12 articles underwent a systematic review. Tablet applications and …

Narrative Storytelling In Conjunction With Environmental Journalism, Abbey Edmonson

Honors Theses

This thesis explores the effectiveness of long-form narrative storytelling in relation to environmental journalism. It particularly focuses on effectively communicating the seriousness of climate change on a local level through narrative storytelling. The bulk of the information was gathered through multiple interviews with people experiencing the effects of climate change on the Mississippi Gulf Coast. By using interviews with local people interspersed with scientific data, I hope to be able to show the average reader that climate change is real and it can dangerously affect people on a local level, even in rural states like Mississippi.

Through my research, I …

Honors Accounting Thesis, Ryan Rodgers

Honors Theses

This thesis contains twelve case studies that pertain to various accounting concepts and matters. The topics vary from 10-K evaluations to blockchain. This thesis was written under the guidance from Dr. Victoria Dickinson during my junior in an Independent Study class (ACCY 420). I benefitted greatly from participating in this class, and it allowed me to gain more knowledge from current accounting situations.

Sizing And Economics Of Solar Powered Indoor Swimming Pool, Aman Bhatta

Honors Theses

With increasing global population and aspiration for higher standards for living, there is a rapid increase in demand for energy. With the concerns of climate change becoming ever more pressing, a shift from the conventional energy source to an alternative green version to meet the energy demand could be of significant interest. A large amount of energy is required to maintain water temperature in the swimming pool at a human comfort temperature. Several studies have been performed to calculate and evaluate the feasibility of powering thermal systems for swimming pools using solar energy. Still, extensive analysis using solar thermal energy …

Exploring Health Insurance Coverage And How It Is Affecting Patients And Providers, Robert Balie Crim

Honors Theses

The American people are struggling to pay for or find good health insurance. Doctors are unable to prescribe them what they actually need. Their insurance might stop paying for the drug that they had been using that was helping them. They might have to try some amount of drugs or treatments before the insurance company will pay for what the doctor has prescribed. Patients might be having to endure more pain for an unnecessary amount of time at the hands of an insurance company. What are the roots of these problems? With the growing complexity and advancing technology, how are …

Comparing Lithic Artifacts And Native American Activity At Stark Farm, An Early Contact Period Site In Northeast Mississippi, Gillian Steeno

Honors Theses

Supposed ancestors of the modern-day Chickasaw, the occupants of Stark Farm inhabited the area known today as Starkville, Mississippi. These Native American peoples left behind archaeological evidence of their occupation, especially in the form of large midden-filled basins. In order to investigate these refuse pits, a lithic analysis was completed using stone typology in order to infer supposed activities. Each of the five contexts are compared to each other to determine which assemblages have similar elements and which ones prove to be unusual in comparison. Through this stone tool analysis, domestic and non-domestic activities and areas in the site can …

Journeying Through Music - Journey To Commencement, Lynn Clark Wilkins

Journey to Commencement

Drummer Michael Ivy puts his energy for performance into the classroom

A Fond Farewell, Bill Dabney

University of Mississippi News

No abstract provided.

B'Ars And Catamounts: A Study Of Davy Crockett Through Genre And Medium, Jack Fieweger

Honors Theses

This project seeks to investigate and discuss the changes and variations that have occurred to the mythology of David Crockett over the course of time. Initially appearing as a literary character in 1833, the likeness of Crockett has appeared in a myriad of different texts including: biographies, almanacs, plays, dime novels, comics, television shows, and films. The project attempts to discern how these different iterations of medium and genre altered the mythology of David Crockett. In order to methodologically understand these changes, this project makes use of W.T. Lhamon’s concept known as the Lore Cycle. Lhamon identified that lore diffuses …

The Impact Of Wine Nutrition And Ingredient Labeling On Consumers’ Attitudes And Purchase Intentions, Kara Tate

Honors Theses

Current TTB regulations do not require that US wine producers display nutrition and ingredient labeling on their wine labels. However, recent attempts at passing legislation to mandate that such information be provided on labels in the EU suggests that US policy makers will soon follow suit. Research on how this addition would impact consumers has been scarce and has been primarily conducted in Europe, but what is available suggests that consumers are unaware of the nutritional values in a glass of wine and many do not look at the back label when selecting a bottle to purchase. We conducted a …

On The Nature Of Collaboration, John Walker

Honors Theses

The senior recital is in and of itself a Capstone project in the Department of Music—a culmination of one’s undergraduate years. Preparation of such a program, especially a collaborative recital with a peer, demands much of a voice student’s attention. However, the nature of this preparation is a relative unknown among the non-musical spaces of academia. Presented with an opportunity to develop my senior recital with Brittany Parry, a student of the new Master of Music in Collaborative Piano, I chose to reflect upon our novelty recital experience in this Capstone paper. The energy we devoted to our rehearsals and …

April 22, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Parkinson's Disease, The Amygdala, And Non-Motor Symptoms, Callie Claire Gammill

Honors Theses

This study sought to explore the relationship between Parkinson’s Disease (PD), the amygdala, and the plethora of non-motor symptoms that plague individuals with PD. Previous research gave insights about the amygdala’s function as the emotional center of the brain, its role in depression, and its participation in the non-motor symptoms of PD. The research proved to still be inconclusive on its own because of a variety of limitations. The methods of this study consist of the analysis of Functional Magnetic Resonance Imaging (fMRI) scans from 93 individuals with PD and 18 individuals without PD while in a resting state. The …

Characterizing Pm2.5 Air Samples Of Northeast Mississippi, Harley Nabors

Honors Theses

Ambient air pollution has been associated with adverse health effects throughout the entire world. Although epidemiologists study air pollution extensively, rural areas are often the least understood. In 2020, the Mississippi Department of Environmental Quality used less than 10 air sampling locations across the state leaving a large gap in air quality knowledge. In this study, fine particulate matter (PM2.5) air samples were collected from three different rural Mississippi cities–Ackerman, Eupora, and Houston, in the summer of 2020. Following collection onto filters, elemental black carbon analysis and an oxidative potential assay were both used to characterize the samples of interest. …

The Politics Of Taxation: An Economic Analysis Of Politically Motivated Tariffs Placed On French Wine By The United States, Katelyn Hutson

Honors Theses

In this paper, I research the economic distortions caused by a 25% retaliatory tariff placed on French wine by the United States in October 2019. This tariff was enacted as retaliation for airline subsidies provided by various European countries to Airbus and was approved by the WTO as a valid compensation for the loss these subsidies caused to the American company Boeing. In order to view the correlation between fluctuations in US import quantities of French wine and the retaliatory tariff, I estimated the effect of the tariff on the wine market using linear regression analysis. Through this regression, I …

Installation Press For Heat Set Inserts, Maxwell Warren

Honors Theses

3D printing has evolved from a slow, laborious process in the 1980s’s to a cutting- edge technology that is being used in industries such as aerospace and medical. Though the technology is relatively new in comparison to CNC machines and other items found in a typical machine shop, additive manufacturing is growing towards a multibillion-dollar industry. For this reason, many industries are turning to 3D printing for research and development tasking as well as just using it to supplement for parts until they have been manufactured through more traditional means. The downside of 3D printing is that it is commonly …

Exploring Manifoldlike Causal Sets And Their Dimensions, Santosh Bhandari

Honors Theses

Causal Set Theory is an approach to quantum gravity that tries to replace the continuum spacetime structure of general relativity with the spacetime that has the property of discreteness and causality. From the standpoint of causal set theory, our spacetime is made up of discrete points that are causally related to one another. A causal set is said to be manifoldlike if it can be faithfully embedded in a Lorentzian manifold. In this thesis, some of the fundamental properties of causal sets are discussed. The first chapter is devoted to the historical background of quantum gravity with a discussion of …

The Politics Of Everyday Subversion: Crisis, Covid-19, And Coming-Of-Age In Córdoba, Argentina, Abby Flickinger

Honors Theses

This thesis seeks to explore the impact of converging political, economic, and public health crises in Córdoba, Argentina in the wake of the COVID-19 pandemic with a focus on youth and practices of protest and resistance. Utilizing interviews, participant observations and ethnographic data in addition to economic and public health statistics, media coverage, and government statements I establish the basis and context for this triple crisis, as well as the tactics appropriated to criticize the government and expression disillusionment — protests and subversion. Despite modifications to public health concerns, the Argentine democratic tradition of protesting returned against government wishes, and …

Moving The Monument: The University Of Mississippi’S Decades-Long Journey To Relocate Its Confederate Monument, Hadley Hitson

Honors Theses

This thesis tells the story of how thousands of students, faculty, staff, alumni and other members of the university community banded together to relocate The University of Mississippi’s Confederate monument. The movement for relocation officially began in the spring of 2019 with the unanimous vote by the Associated Student Body Senate to move the monument to UM’s Confederate cemetery, but long before that, change happened at the university that paved the way.

This creative telling of recent history explains how national and local events — including pro-Confederate marches in Oxford and the police murder of George Floyd in Minneapolis — …

Q&A With Charlesa Peters (Bfa Imaging Arts), Charlesa Peters

Q & A Interviews with Art Students

No abstract provided.

Studies On Synthesis Of Pyrazole From Dibromo And Hydrazine Compounds., Riya Trivedi

Honors Theses

Depression has become the fourth leading case for mortality and morbidity in the world. It is a leading cause of disability worldwide and is a major contributor to the overall global burden of disease. Current treatments of depression are inadequate, and the progress in understanding the neurobiology of depression is slow. The first generation antidepressants like monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs) have shown to possess a lot of side effects. Hydrazide-based monoamine oxidase inhibitors are known to result in acute hypertensive crises and hepatotoxicity, as well as to interact with many foods and biogenic amine drugs. Tricyclic …

Surface-Eroding Drug Delivery Films For Sequential And/Or Intermittent Release Of Psychoactive Drugs, Jason Price

Honors Theses

ABSTRACT JASON BLAKE PRICE: Surface-Eroding Drug Delivery Films for Sequential and/or

Intermittent Release of Psychoactive Drugs For patients with psychiatric diseases, adherence to medication schedules, medication

errors, and abuse are common issues. Promising new forms of therapy for these patients, such as micro-dosed lysergic acid diethylamide (LSD), where patients receive 10-20% of a full dose every third day, present further drug delivery challenges. Sequential or intermittent release of drugs from an implanted device could ensure long-term drug compliance, automate drug dosing during the life of the implant, and eliminate potential for abuse and medication errors. To this end, we generated …

April 15, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Measurements Of The Branching Fractions Of Λc+ →Pη And Λc+ →Pπ0 Decays At Belle, S. X. Li, C. P. Shen, I. Adachi, J. K. Ahn, H. Aihara, D. M. Asner, T. Aushev, R. Ayad, V. Babu, S. Bahinipati, P. Behera, J. Bennett, F. Bernlochner, M. Bessner, V. Bhardwaj, B. Bhuyan, T. Bilka, J. Biswal, A. Bobrov

Faculty and Student Publications

We report measurements of the branching fractions of singly Cabibbo-suppressed decays Λc+→pη and Λc+→pπ0 using the full Belle data sample corresponding to an integrated luminosity of 980.6 fb-1. The data were collected by the Belle detector at the KEKB e+e- asymmetric energy collider. A clear Λc+ signal is seen in the invariant mass distribution of pη. The fitted number of signal events of the Λc+→pη process is 7734±263; from this, we measure the ratio of branching fractions B(Λc+→pη)/B(Λc+→pK-π+)=[2.258±0.077(stat)±0.122(syst)]×10-2, from which we infer the branching fraction B(Λc+→pη)=[1.42±0.05(stat)±0.11(syst)]×10-3. In addition, no significant signal for Λc+→pπ0 is found, so an upper limit on …

Wobbling The Foundations Of The Universe, Shea Stewart

University of Mississippi News

UM researchers part of experiment that finds strong evidence of undiscovered particles, forces

Theory And Practice: Selecting And Implementing Effective Framing To Present Climate Science To A Lay Audience, Lauren Wilson

Honors Theses

The purpose of this thesis is to explore the advantages and effectiveness of using storytelling in the form of narrative journalism to communicate the topic of climate science to a lay audience. The thesis combines personal experience with secondary research in order to support the claim that framing the issue in such a manner effectively communicates the severity and impact of climate change.

Through my research I discovered that storytelling is not only a social tool for humans, but a means to safely and efficiently pass on vital information to those unfamiliar with certain knowledge. The use of narrative has …