Digital Commons Network^™

Combined In Silico And Experimental Approaches Of Pharmacognosy To Resolve Complex Natural Product Issues, William Michael Neal

Electronic Theses and Dissertations

Since the identification of useful bioactive natural products can often involve tedious dereplication measures to decipher complex mixtures, much emphasis is placed on methods that can effectively characterize natural products. Several in silico methods, such as quantitative structure-activity relationships (QSARs), molecular docking, and quantum calculations, provide researchers with valuable tools to overcome the challenge of complex natural product mixtures. To exemplify the abilities of computational methodologies to further the field of pharmacognosy, this dissertation elaborates on several research projects involving computational approaches in pharmacognosy, including: (1) global assessment of pregnane X receptor (PXR) agonism via multiple QSAR models, (2) differentiation …

Research News, Publications, 2024, Volume 4, Joshua Sharp

Publications (2015-)

Publications that appeared during the period of October 1 - December 31, 2024.

Essays On The Greek Debt Crisis And The Welfare Paradox In The Lucas Natural Rate Model, Liandong Yang

Electronic Theses and Dissertations

This dissertation includes two projects, one on the Greek debt crisis and the other on the welfare in the Lucas natural rate model.

The first chapter discusses the origin of Greek debt crisis. The Greek debt crisis stands out as a compelling case study of a severe financial crisis in a developed country within a currency zone. Despite the abundance of literature on the subject, the significance of debt accumulation in the 1980s is often overlooked, and details are frequently omitted. Through an analysis of data gathered from Greek government’s public finance statistical yearbooks spanning from 1962 to 2008, I …

Apartments, Michael Pontacoloni

Electronic Theses and Dissertations

The following poems engage with themes of placemaking in the twenty-first century. A critical introduction centers the accompanying poems within a developing tradition of poetry in the twenty-first century that challenge common conceptions of home, romantic relationships, and transience. Other topics approached in the poems include adolescence, the environment, sport, and friendship.

The Impact Of Perception Of L1 Stress Features On L2 Perceived Fluency, Tian Zhang

Electronic Theses and Dissertations

This study investigated the influence of stress on perceived fluency, a critical dimension of fluency study, alongside utterance and cognitive fluency. Perceived fluency is defined as the inferences listeners make about speakers’ cognitive fluency based on their perceptions of utterance fluency (Segalowitz, 2010). Previous research demonstrated that factors such as pause phenomena and speech rate significantly affected subjective fluency ratings (Bosker et al., 2012; Kahng, 2018). Stress was also identified as a contributing factor through qualitative analysis (Préfontaine and Kormos, 2016), yet had not been thoroughly examined using quantitative methods.

The cue-weighting theory of speech perception suggests that listeners from …

Juvenile Coping And General Strain Theory, Peyton Conner Stephenson

Electronic Theses and Dissertations

The purpose of this study is to quantitatively assess the impact of victimization on behavioral and emotional outcomes among a sample of adolescents detained within the juvenile justice system. Specifically, the study focuses on understanding the relationship between reports of victimization (e.g., being beaten up or threatened) and maladaptive coping mechanisms, such as involvement in fighting. To do so, Agnew’s (1992) General Strain Theory (GST) and the Pains of Imprisonment are adopted as frameworks for understanding the role of strain or stressors in prompting deviant behavior as a coping mechanism. This study uses secondary data from the Northwestern Juvenile Project …

Grace Satellite Spatial Resolution Downscaling Using Machine Learning: Methods And Applications, Abdel Rahman M. Awawdeh

Electronic Theses and Dissertations

The Gravity Recovery and Climate Experiment (GRACE) satellite mission has been instrumental in advancing our understanding of global water dynamics, providing unprecedented insights into terrestrial water storage (TWS). Despite its revolutionary contributions, the coarse spatial resolution of GRACE data (~300 km² grids) limits its utility for local-scale water resource management, particularly in regions requiring detailed hydrological analysis such as the Mississippi Delta. This dissertation addresses this limitation by developing and validating machine learning models to enhance the spatial resolution of GRACE data, thereby facilitating more precise and effective local water management strategies.

This research first establishes a comprehensive background in …

Developing And Validating A Novel Screening Instrument For General Psychological Distress, Steven M. Bishop

Electronic Theses and Dissertations

This study presents the results of both factor analyses in developing the General Psychological Distress Screener (GPDS), and provides preliminary data of its predictive validity. As a new screening instrument, the GPDS assesses mental fatigue and emotional distress in adults and predicts certain psychiatric disorder diagnoses. Drawing upon network analysis principles, two studies were conducted to construct and refine the GPDS. Study 1 identified the variable constructs from psychopathology networks that were used in Study 2. Study 2 used principal axis factoring to develop a 4-factor solution, which was subsequently reduced to a 2-factor model for improved interpretability. Confirmatory Factor …

Godspeed: American Evangelicals And The Space Race, Kari Edwards

Electronic Theses and Dissertations

When the Space Race between the United States and the Soviet Union erupted in 1957 with the launch of the Sputnik 1 satellite by the Soviets, Americans were forced to face a disturbing new reality: the world had changed, humanity had reached into space, and the United States had not been the first nation to accomplish such a feat. In a Cold War climate dominated by religious concepts of good versus evil, American evangelicals approached the birth of space exploration with some reluctance, unsure whether such magnificent feats were truly blessed by God and struggling to come to terms with …

The Effects Of Technology-Enhanced Learning On Radiologic Sciences Student Engagement, Zack Gray

Electronic Theses and Dissertations

This dissertation investigates the multifaceted connection between technology-enhanced learning (TEL) and student engagement, with a specific emphasis on student perceptions, attitudes, and distractions associated with technology usage in the classroom. Recognizing the increasing prevalence of technology in educational settings, this study seeks to understand how students perceive technology in the learning environment and how these perceptions influence their attitudes toward its use. The research framework is anchored in the Theory of Planned Behavior (TPB), providing a theoretical lens to assess the cognitive factors influencing student behavior.The study employs a mixed-methods approach, combining surveys and observations to gather comprehensive insights into …

Weak Disorder Limit On Diamond Hierarchical Graphs With Vertex Disorder In The Critical Case, Casey Reid Lochridge

Electronic Theses and Dissertations

We compare three models for a directed polymer in a random environment (DPRE): the rectangular lattice, the branching lattice, and the diamond hierarchical lattice. Our focus is primarily on the diamond model, in which the polymers traverse a recursively defined diamond graph with a random environment composed of random variables indexed by the vertex set. The diamond graphs are constructed iteratively according to a given branching parameter b ∈ {2, 3, 4, . . .} and segmenting parameter s ∈ {2, 3, 4, . . .}, and our main result concerns the critical case b = s. In this case, …

Southern Animals: Multispecies Encounters In Midcentury Southern Fiction, Kacee M. Mckinney

Electronic Theses and Dissertations

This dissertation expands our understanding of how nonhuman animal figures, symbols, and encounters within southern literature have had ideologically profound impacts on our conceptions of humanity, southernness, and relationality. This dissertation examines prose fiction, including short stories, novellas, and novels, from four influential southern writers—Richard Wright, Carson McCullers, Tennessee Williams, and Flannery O’Connor—who were all actively engaged with representing, critiquing, and expanding American conceptions of the south, the nation, and the ‘human’ at midcentury. With an understanding of southern literature as a rich site for not only regional representation but also broader disruptions of national injustices and ideologies of domination …

Improving American Learners’ Pronunciation Of Arabic Pharyngeals: Traditional Vs. Tbi Method, Yasmine Sedeek

Electronic Theses and Dissertations

Mastering the phonological aspects of a second language (L2) poses significant challenges for adult learners, often affecting their intelligibility in acquiring that language (Derwing, Munro, & Wiebe, 1998). McAllister (1997) has highlighted L2 learners’ struggles in perceiving and producing novel segmental features, which is corroborated by The Perceptual Assimilation Model of L2 speech learning (PAM-L2) proposed by Best & Tyler (2007), which posits that the perception of L2 phonetics is a critical precursor to their accurate production. Against this backdrop, the present study aims to improve the intelligibility of Arabic pharyngeals (/ʕ/ and /ħ/) among English-speaking learners studying Arabic as …

Evaluation Of Male And Female Performance And The Role Of Cerebellar Lesions And Local Aromatase Inhibition In Motor And Cognitive Tasks In The Zebra Finch (Taeniopygia Castanotis), Mathew Joseph Thibodeaux

Electronic Theses and Dissertations

Most studies involving sex differences in songbirds are devoted to song learning and development. However, songbirds, such as zebra finches, are excellent models for studying general roles of steroids on behavior post-brain injury because they have high degrees of adult neuroplasticity and neurosteroidogenesis. The role of estradiol (E2) in recovery of function after neural insults in mammals has been well-studied for decades. Only recently has the role of E2 and aromatase in neuroprotection been examined in songbirds, and our lab is one of the few to study the role of E2 and aromatase in behavioral recovery and the only to …

Title Character: A Novel, Di Bei

Electronic Theses and Dissertations

Inspired by true events, Title Character: A Novel tells the intimate and fraught relationships of Asian female artists during a pandemic in Idaho: Jade, a rebellious girl born amid the one-child policy in Beijing, writes her love story into a script; Pearl, an ambitious actress raised in rural China, stars in Jade’s film and dates the method actor who plays her lover. Strung together by one film, young women of the Asian diaspora mirror and maneuver each other, while playing out their performances of self with art as their arena.

The Role Of L1 Dialect Phonotactics On The Production Of L2 English Phonotactics By Saudi Efl Learners, Abdullah Ahmad Balbaid

Electronic Theses and Dissertations

This study investigates the phonological challenges and adaptive strategies employed by 30 first-year university students majoring in English from three distinct Saudi Arabian dialect backgrounds—Najdi, Hijazi, and Hasawi—in perceiving and producing English onset biconsonant and triconsonant clusters. Exploring dialectal variations, the research aims to understand how these phonological characteristics influence the acquisition and intelligibility of English pronunciation among Saudi learners. Utilizing a combination of perception tasks through ABX discrimination tasks and production tasks inspired by the Labovian model, the study provides insights into the dialect-specific phonological challenges faced by the participants.

Key findings reveal that Najdi speakers demonstrate higher proficiency …

Development Of Fenofibrate Solid Dispersion Via Hot Melt Extrusion And 3d Printing Technologies, Janhavi Santosh Deshmukh

Electronic Theses and Dissertations

The aim of this study was to develop an amorphous solid dispersion (ASD) of fenofibrate using Hot Melt Extrusion (HME) and 3D printing. By using HME, 3D printable filaments were prepared. Fenofibrate (10% w/w), Soluplus®, and Polyethylene oxide-N80 were used to prepare the HME filaments. The filaments were divided into two parts, the first part was used as a feedstock for the Fused disposition modeling 3D printing (FDM 3D printing) to print fenofibrate tablets with different percent infill densities, 90%, 70% and 50%. The second part was milled and filled into gelatin capsules to compare the dissolution release profile of …

Exploring The Habits And Perceptions Of True Crime Podcast Listeners, Remy Heinen

Electronic Theses and Dissertations

Although podcasts as a whole are growing in popularity, the true crime genre of podcasts continues to be especially popular, particularly with female listeners. The unique intersection of informational and entertainment goals associated with true crime podcasts raises ethical questions about how these priorities should be balanced. This study focused on learning more about listeners’ motivations, habits, and perceptions via an online survey. Additionally, it explored the gendered nature of true crime podcast consumption. A total of N = 657 participants completed the survey providing information about why they listen to true crime podcasts, how often they listen, and how …

On Inference-Time Adversaries In Object Detection Models, Soumil Datta

Electronic Theses and Dissertations

With the increasing use of AI in various applications, its ability to impact different communities is a crucial aspect to the advancement of humanity and technology. However, with its often unexplained properties, AI models could wreck havoc if loopholes are found. Adversarial attack algorithms have been shown to cause deep neural networks to fail on image classification and object detection tasks while being visually imperceptible to humans. Adversarial attacks cause out of distribution predictions and can cause the model to fail in unexpected ways.

Magnolia State Of Mind: Memory And Memorialisation In Mississippi, Cosmo Mcgee

Electronic Theses and Dissertations

This thesis explores the ways Mississippi has historically and contemporaneously crafted its collective memory through symbolism. Confederate memorial groups endeavoured to create a “Lost Cause” memory of the state’s Antebellum past, validating its White supremacist systems into the 1960s. With the violence of the Civil Rights era failing to stop integration, Mississippians would spend the next sixty years debating the best ways to represent the state’s history.

This work looks at three distinct manifestations of Mississippi’s memorial culture: the discussions around and changes to the state flag, the cultural and sporting atmosphere of the University of Mississippi (“Ole Miss”), and …

As Lightning, Lenna Mendoza

Electronic Theses and Dissertations

A collection of poems.

Spins And Kicks: An Analysis Of Dynamical Properties Of Compact Binaries Using Gravitational Waves, Sumeet Kulkarni

Electronic Theses and Dissertations

The detection of over 90 compact object mergers involving black holes and neutron stars as gravitational wave events by the Advanced LIGO and Advanced Virgo detectors over the course of three observing runs has ushered in the new era of gravitational wave astrophysics. Within a decade, we have transitioned from a detection to the population era, with a combined catalog of these events making it possible to study the population properties of compact objects, estimate their local merger rate, and provide clues as to how they can form binaries. This dissertation focuses on two particular displays of the dynamical dance …

Montesquieu: The Nature Of L’Esprit Des Lois, Christian Jax Murray

Electronic Theses and Dissertations

When Baron de Montesquieu received a copy of his L’Esprit des lois, he was horrified by the total removal and reorganization of critical parts of his text, changed ideas, and an abnormal amount of printing errors in his work. While he saw these issues hindering the reception of his work, this thesis argues that the chaos of the text, in both its style and publication, made the book more popular instead of hindering it. Montesquieu, his editor, and his publisher constructed a new kind of text that was broad in its subject matter and ambiguous in its meaning where its …

The Impact Of Team Success And Team Dynamics On Employee Effort, Tina S. Owens

Electronic Theses and Dissertations

I experimentally examine how team success affects individual employees’ attribution of their own poor performance and whether inter-team dynamics impact their subsequent efforts. I argue, using attribution theory, that more successful, relative to less successful, team performance will lead employees to take more responsibility for their own poor performance and, thus, make more positive effort adjustments. This is because employees are more likely to accept responsibility for their poor performance when they learn that their team as a whole performed well. Additionally, using social identity theory, I argue that employees on teams with stronger team dynamics will make more positive …

Moving Minds: Examining The Potential Effects Of Movement On Executive Function Among 3-Year-Olds, Zubie Reagan Pearce

Electronic Theses and Dissertations

This study aimed to examine the effect of movement on the conscious control of behavior (i.e., executive function or EF) in three-year-old children. Two questions were addressed regarding the role of movement in preschoolers' EF. First, the study investigated how altering movement within EF tasks influenced children's EF performance by manipulating relevant motor patterns (i.e., arm movement within EF searching and sorting tasks) in 3-year-olds. Children wore slightly weighted armbands while engaging in two distinct EF tasks, one focusing on motor control (i.e., reaching for an object) and the other on cognitive control (i.e., sorting objects based on rules). Second, …

Mirroring The Target Environment: Text And Task Authenticity In Esl Business Textbooks, Kurt Wildon Smith

Electronic Theses and Dissertations

This dissertation investigates the utilization of authentic reading materials in ESL textbooks and the role that textbook-based tasks serve in enabling ESL classrooms to mirror the target environment. Three original studies are conducted, and two models are designed and applied in order to address the research questions, which aim to establish a standard metric for assessing semi-authenticity of materials and to determine to what degree ESL textbooks prepare students for utilizing subsequent academic textbooks in similar topical areas. Textbooks developed for ESL business and academic business courses are analyzed to determine task category prevalence, reading texts in the ESL genre …

Energy Efficient Communications For Signal Detection Using Wireless Sensor Networks, Shailee Yagnik

Electronic Theses and Dissertations

We consider a wireless sensor network where several sensors receive observations to detect the presence or absence of a deterministic signal in Gaussian noise. In this context, we consider two problems. In the first problem, subject to power constraint across all sensors, we focus on optimizing individual sensor transmit power to enhance the probability of correct decision performance. In the second problem, we concentrate on achieving energy savings by an implementation of sequential transmission involving ordered transmission process from the sensors to a fusion center (FC). Both problems have a focus on energy savings, with ordered transmission requiring timing and …

Investigation Of Evolution In Fungal Traits At Multiple Genetic Scales, Brooke Allen

Electronic Theses and Dissertations

The study of fungal traits is critical for understanding community assembly and ecosystem function, as traits related to resource acquisition, enemy avoidance, and stress tolerance link fungi to their ecological roles. Symbiotic relationships, such as those between ectomycorrhizal (EcM) fungi and their host plants, greatly influence fungal traits and play a key role in fungal evolution. In this study, we addressed the evolution of EcM fungal traits, particularly biosynthetic gene clusters (BGCs), at multiple genetic scales, including individual genes, genotypes within populations, and a broader phylogenetic perspective across the fungal kingdom. First, we surveyed the diversity of BGCs in native …

Attitudes Toward Arabic-Accented Speech In English, Sarah Aldossari

Electronic Theses and Dissertations

The study explores the attitudes of undergraduate Flagship students in the United States towards Arabic-accented speech in English. It examines the Familiarity Principle among these students and analyzes their attitudes based on socio-intellectual status, aesthetic quality, and dynamism of Arabic-accented speech. The study also discusses the relationship between pronunciation features and language attitudes and intelligibility of communication.

The study used mixed methods to collect and analyze data on students' attitudes towards Arabic-accented speech. It used a verbal-guise technique, a Speech Dialect Attitudinal Scale questionnaire, and semi-structured interviews. The questionnaire data revealed that 54% of students valued socio-intellectual status, 48% aesthetic …

Branching Fraction Measurements Of Ξc + → Σ+H+H− And Λc + → P+H+H− Using Belle Ii Monte Carlo, Azwad Adnan

Electronic Theses and Dissertations

Charmed baryon decays are a great place to probe and search for physics beyond the Standard Model. The Belle II experiment is equipped to explore this area with high statistics datasets to shed light on any potential anomalies. In addition to searches for new physics, the Belle II data samples can be used to make SM measurements that are either missing, statistics limited, or require confirmation.