Digital Commons Network^™

Bax Activation Through The N-Terminal Bh3-Like Domains Of Vdac1 And Vdac2, Autumn A. Peters

Honors Theses

Voltage-dependent anion channels (VDACs) are central to mitochondrial function by mediating metabolite diffusion across the mitochondrial outer membrane (MOM). Two isoforms­­­­­­­­­­­,­­­­­­­­­­­­­­­­­­­­­­­­­­­­ VDACs 1 and 2, are also implicated in apoptosis based on interactions with Bcl-2 family proteins that control this process, including Bax and Bcl-xL. Activation of the pro-apoptotic protein Bax by interaction with ‘BH3-only’ proteins, such as Bim or Bid, induces MOM permeabilization to signal apoptosis, yet accumulating evidence indicates VDACs 1 and 2 may also affect Bax. We discovered that the VDAC N-terminal domains contain high sequence similarity to the conserved BH3 domains within Bcl-2 family members that …

Design And Production Of A Carbon Fiber Longboard, Jacob T. Williams

Honors Theses

This thesis contains an overview of the design, prototyping, and manufacturing of a carbon fiber long board. The purpose of this capstone was to create a viable product for the real-world market and then determine how to manufacture it at scale with sustainable financial practices. In order to accomplish this task, engineering, accounting, and manufacturing challenges had to be overcome throughout all stages. The production process involved the carbon fiber layup, baking, water jet cutting, and assembly of the carbon fiber longboard. In order to optimize this process, continuous improvement and lean manufacturing problem solving techniques were applied. After a …

"En Papel,” Not In Practice: Indigenous Autonomy And The Structural Barriers To Land And Resource Control In Bolivia, Andrew F. Purcell

Honors Theses

This thesis examines why Bolivia’s 2009 plurinational constitution—despite its strong recognition of Indigenous autonomy, collective territory, and prior consultation—often produces rights that remain “en papel” rather than in practice. Based on one month of fieldwork in Tumupasa, Chojasivi, La Paz, El Alto, and Santa Cruz, the study draws on interviews, participant observation, and NGO documents to analyze the structural barriers that prevent constitutional guarantees from becoming enforceable governance tools. This gap between recognition and implementation structures the central research question: why do Bolivia’s constitutional and legal protections for indigenous land and resource rights function as symbolic guarantees rather than enforceable …

Analyzing Best Practices In Large-Scale Digital Archaeological Databases, Chloe M. Vizier

Honors Theses

Archaeological databases, the foundation of archaeological analyses, have changed drastically alongside the rise of new digital tools in the twenty-first century. Digital databases, alongside other digital tools, must therefore be evaluated for their efficiency and effectiveness within the field. This thesis seeks to determine a set of best practices within large-scale digital archaeological databases through analyzing an existing example: The Paleoindian Database of the Americas (PIDBA). PIDBA is composed of multiple state-level datasets, a trait that both invited collaboration and creates discrepancies in data entry. Though examining both PIDBA's user-facing website and one of its most robust state-level datasets, the …

Expanding Expanded Access: A Case Of Onc201 And The Ethical Limitations Of Compassionate Use, Ava C. Hutchings

Honors Theses

This study examines the ethical and structural limitations of the Expanded Access program in the United States, with particular focus on its application to terminal pediatric illness. Although the program is intended to provide patients with life-threatening conditions access to investigational therapies outside of clinical trials, its effectiveness in serving critically ill children remains uncertain. This program is analyzed through careful consideration of regulatory review and ethical theory. Key policies governing Expanded Access are examined alongside scholarly discussions of pediatric autonomy and parental authority.

A case study of ONC201, a now-approved investigational drug, is used to illustrate how Expanded Access …

The Design And Manufacturing Process Of The Concealed Shelf, Mexrojiddinbek Sattorov

Honors Theses

This document contains information regarding the design and build process of the Concealed Shelf, which is a furniture product with hidden storage capability. First, the team members decided on the design of the product, followed by market analysis and manufacturing feasibility. Lean manufacturing principles were applied to improve the process efficiency and reduce waste.

Multiple prototypes were built with varying raw materials and locking mechanisms. Jigs and fixtures were handcrafted to ensure more consistent product quality. Two production runs were conducted to evaluate performance and identify areas for improvement.

The final design includes economic considerations, manufacturing layout, and continuous improvement …

Optimization And Safety Protocols For An Acetone Production Plant, Holley J. Garrison

Honors Theses

The proposed acetone production plant, scheduled for start-up in 2028, is capable of producing 3,750 kg/h of 99.9 wt% acetone. Using an endothermic catalytic dehydrogenation reaction, a feed of isopropyl alcohol (IPA) is reacted to produce 30,000 metric tons per year (MT/y) of acetone. Initial design and economic analysis of this process found that this plant will not be economically viable due to its Net Present Value (NPV) of -$132M. Optimization efforts prioritized reductions in raw materials and improved product recovery. Several optimizations were performed to reduce the feed rate, including switching to the low temperature catalyst, shortening the reactor …

School Of Education Alumna Begins Second Term Leading Advisory Board, Don Feitel

University of Mississippi News

OXFORD, Miss. – Kathleen Grigsby has been reappointed to a second term as president of the University of Mississippi School of Education board of advisers.

Red And Blue Celebration Honors Staff Graduates, Tim Kephart

University of Mississippi News

OXFORD, Miss. – As the University of Mississippi prepares to honor its latest class of graduates, several of that group are dedicated staff members who pulled double duty working and completing degrees.

Exploration Of Ai-Based Method Feedback For Clinical Psychology Skill Development With An Emphasis On Deliberate Practice, Beckham G. Mccord

Honors Theses

Training competent psychotherapists requires substantial time, supervision, and performance-based feedback. However, traditional methods of providing feedback are resource-intensive and difficult to sustain outside of university and research settings. Recent advances in artificial intelligence (AI) have created new opportunities to automate aspects of psychotherapy fidelity assessment and provide trainees with more frequent feedback. The present study examines the implementation of Lyssn, an AI-based psychotherapy platform that provides clinical feedback to therapists, in a graduate-level course on Evidence-Based Services. Multiple years of course data were reviewed to evaluate therapist competence, therapist behaviors, and student engagement with AI-generated feedback. Particular emphasis was placed …

From Amateur To Influencer: The Nil Era Takes Over, Olivia J. Matulich

Honors Theses

This thesis examines the change of amateur athletics with the rise of Name, Image, and Likeness (NIL) rights. For many years, the NCAA followed an amateurism model that prevented student-athletes from earning money, even though their efforts generated major profits through media contracts, sponsorships, and branding. The arrival of NIL in 2021 marked a major shift, allowing athletes the chance to earn money from their personal brand, which redefined the role they play within the collegiate athletic system.

This study looks at NIL from several angles, including its legal background, financial impact, and cultural significance. By reviewing key legal cases …

Bridging Theory And Application: Case Studies In Financial Reporting, Regulation, And Ethics, Keili Cm Ikemori

Honors Theses

This thesis explores the intersection of financial reporting, regulation, and ethics through a series of applied case studies designed to bridge theoretical accounting concepts with real world application. The case studies focus on how accounting principles are implemented in corporate environments, how regulatory frameworks influence business operations, and how ethical considerations shape financial decision making. During the fall semester of Accy 420, we were tasked with case studies that increased our knowledge in financial statement literacy, accounting concepts, relevant accounting regulations, and ethics. During the spring semester of Accy 420, we used the knowledge gained from the prior semester in …

Examining The Rural Workforce: Comparing Admissions Strategies And Training Pathways In U.S. Medical And Dental Education, Charolyn A. Harris

Honors Theses

Access to healthcare in rural and underserved communities remains a significant challenge in the United States, particularly in dental care, where workforce shortages are more pronounced. This study examines how medical and dental education programs develop rural healthcare providers, focusing on admissions strategies and training pathways. Using a structured scoping review and secondary data analysis, this research compares how each field incorporates known predictors of rural practice, such as rural background and training experiences, into workforce pipeline development. Findings indicate that while both medical and dental education recognize rural background as a strong predictor of rural practice, medical education more …

The Practice Book: An Interactive Website For Figure Skating Training Plan Development, Lydia J. Popple

Honors Theses

Figure skating training relies on structured practice plans developed by coaches to guide athlete progression. However, many coaches and skaters continue to use paper-based or fragmented digital systems, limiting organization, accessibility, and visibility into athlete progress. This project introduces The Practice Book, a web-based application designed to digitize and centralize the creation, assignment, and tracking of figure skating practice plans.

The system is implemented using a three-tier architecture with a PHP-based application layer, a MySQL (MariaDB) relational database, and a user interface built with HTML, CSS, and Bootstrap. The database models standardized figure skating elements defined by the United …

Pop Prophets: How Celebrity Culture Shapes Gen Z'S Worldview, Olivia G. Usie

Honors Theses

Generation Z has grown up in a social environment shaped by constant connectivity, digital communication, and immediate access to the lives of others. Because of this, celebrity culture and pop culture may play a larger role in shaping attitudes, behaviors, and identity than they did for previous generations. This study explores how celebrity culture shapes Gen Z’s worldview through four areas: pop culture, celebrity, herd mentality, and cancel culture.

A mixed-method approach was used. Quantitative data was collected through a 28-question survey of 202 participants ages 18–25. Qualitative data was gathered through one focus group of eight participants and three …

Financial Reporting, Strategy, And Legislation: A Study Of Post Holdings And Relevant Accounting Topics, Noah Harkins

Honors Theses

This thesis examines multiple areas of financial reporting, business strategy, and legislation. This was performed through a series of case studies completed in Accounting 420, where the purpose of the class was to apply accounting concepts to real-world business situations. The cases cover multiple areas of financial reporting, including asset theory, 10-K analysis, audit risk assessment, corporate legislation, business strategy, data analytics, economic policy, and professional leadership. The main analysis focuses on Post Holdings, with supporting cases involving Tyson Foods, the Corporate Transparency Act, Thomas Sowell, Ronald Reagan, and broader accounting theory.

The research process used throughout the thesis consisted …

The Rise Of Realism And The Search For Justice In 19th Century Literature, Isabella R. Clark

Honors Theses

This thesis follows parallel legal and literary arcs towards “Realism.” While these two movements do not have the exact same timeline, they both characterized the 19th century. This thesis intertwines the literary shift towards writing that more closely resembles reality with the legal realist aim at a justice that more closely relates to its society. As we look at three novels from the 19th century, we will see how the change in literary form relates to a change in legal philosophy as the popular literary style and goal was later formalized by the law. In our study of each novel, …

Storytelling As A Pedagogical Tool For Improving Memory In Lectures, Sydney E. Rutter

Honors Theses

The purpose of the study was to examine if utilizing storytelling in lectures caused a positive effect on students' memory over a week-long period. Storytelling has been used as a mnemonic device to improve memory, however its benefits have not been experimented much in higher education. In this study, 53 undergraduate psychology students were placed into two groups: traditional lecture or storytelling lecture. Students then watched the lecture they were assigned, both lectures discussed the ASURE model. A week later, students returned and took a 17 question memory test. Results indicated that students who watched the storytelling lecture performed significantly …

Listen To Your Parents: An Exploration Into Why Mississippi Foster Parents Enter, Stay In, And Exit The System, Howell D. Jenkins Iii

Honors Theses

Like many states across the country, Mississippi’s foster care system has faced a shrinking pool of foster parents to care for the state’s most vulnerable children. When states do not have adequate numbers of foster parents, children are susceptible to negative outcomes such as developmental delays, broken attachments with adults, and extended stays in the system. This thesis seeks to understand what motivates individuals to become foster parents, how they experience the system, and what pressures influence their decision to remain fostering or close their doors. To place this research within the appropriate contexts, the thesis draws on literature from …

An Analysis Of Accounting Topics Through Case Studies, Nathan J. Hilzinger

Honors Theses

This thesis discusses and evaluates various contemporary accounting topics and issues through five different case studies in both a group and individual setting. These cases are intended to give students an opportunity to research a broad range of topics and get an in-depth view of different companies, economists, and current events relating to accounting and broader business topics. Through this process students are required to use their financial accounting knowledge gained from previous classes, critical thinking skills, and continue to develop their writing skills in both an educational and professional capacity. The content of this thesis is largely derived from …

An Evaluation Of Modern Accountancy: Insights On Regulatory Change, Corporate Behavior, And Financial Reporting, Cade S. Black

Honors Theses

The purpose of the course was to develop a series of case studies across various areas of financial reporting. These cases covered a broad range of accounting topics, including research on enacted reporting laws to the financial impact of potential regulations on global food companies. To build these cases, we were assigned to teams to research our topics and accumulate credible information to answer the questions given for each case. We also pursued individual cases in which the course had the opportunity to express their opinions as the assigned case was being built. This process ultimately required thorough research of …

Penitential Systems In The Latin West And Byzantine East, Elijah C. Dodson

Honors Theses

This thesis examines the development and organization of penitential discipline in early medieval Christianity through a comparison of the penitential tradition associated with Theodore of Canterbury in the Latin West and the canons attributed to John the Faster in the Byzantine East. The study focuses on how these texts regulated sexual sin and what their structures reveal about the institutional role of the Church in different historical contexts. The analysis is based on a comparative reading of penitential texts, supported by patristic writings and modern scholarship. By examining how specific categories of sexual misconduct are classified and disciplined, this study …

Beyond The Bricks: The Friends Of The Burns-Belfry Online, Madeline M. Webb

Honors Theses

This capstone project was completed to offer a new website to the members of the Friends of the Burns-Belfry Museum and Multicultural Center. This project entailed research into the importance of a museum’s digital presence, the significance of community and cultural spaces for historically marginalized groups, and the role of community engagement initiatives for students and community leaders. All findings were considered and implemented into the website and website manual deliverables.

Hospitalidad Sin Barreras: A Place-Based Approach To Resource Accessibility For Immigrant Communities In North Mississippi, Jackelyn Facio

Honors Theses

This project examines barriers to resource access for Spanish-speaking immigrant communities in Lafayette County, Mississippi. Using a place-based community engagement approach, the project incorporates mixed methods to produce a resource guide for Spanish- speaking immigrants in Lafayette County. Findings showed that access is shaped not only by available services, but also by interconnected barriers such as language, fragmented information systems, and concerns related to trust and safety. These barriers discourage individuals from interacting with formal institutions, resulting in a reliance on informal information networks. In response to the data collected from area residents, the project sought to centralize community input …

Unequal Paths: Experiences Navigating The U.S. Naturalization Process And The Role Of Education, Cecilia Rayburn

Honors Theses

This study examines how educational attainment shapes immigrants’ experiences with the U.S. naturalization process, with a focus on how education influences confidence, access to resources, and the ability to manage bureaucratic demands. While the legal requirements for naturalization are standardized, the ability to navigate them varies widely across individuals. Applicants’ experiences reveal that the U.S. naturalization process is often more complex and unequal than it may appear. This research was conducted through five semi-structured interviews with naturalized citizens of varying levels of higher education. These interviews explored participants’ experiences with the application process, including their preparedness, access to support systems, …

Spaceforge: Spatial Reconstruction For Signal Simulations, Compton Ross

Honors Theses

Signal simulation environments require accurate three dimensional representations of physical spaces, yet current methods for generating these representations, including Light Detection and Ranging (LiDAR) scanning, manual 3D modeling, and commercial photogrammetry, are both costly and time intensive. SpaceForge addresses this gap with a prompt guided pipeline that takes an ordinary indoor photograph and a configurable set of simulation relevant object categories as input and produces a voxelized 3D scene compatible with downstream signal simulation workflows. The pipeline proceeds through five major stages: open set object detection and segmentation, object level preprocessing, single image 3D mesh reconstruction, heuristic pose estimation and …

Joy Beyond Circumstance: Crafting A Picture Book That Challenges Western Perceptions Of Joy, Sarah L. Stockett

Honors Theses

This thesis explores the creation of a children’s picture book as a method of challenging Western perceptions of happiness, particularly the assumption that material abundance determines joy. Drawing from two service-based experiences with Zoe Ministries in Kitale, Kenya, the project centers on The Glad Rag, a picture book in which a single piece of fabric travels through many hands and becomes many useful items. Through this narrative, the book invites young readers to consider resourcefulness, gratitude, and joy that transcends circumstance.

The project uses a mixed-methods research approach. Primary data were gathered through participant observation and informal conversations on …

The Politics Of The Spotlight: Exploring High-Profile Witnesses In Congressional Committee Hearings, Wesley J. Templet

Honors Theses

This thesis examines how the use of high-profile witnesses in congressional committee hearings relates to legislative effectiveness in the U.S. House of Representatives. While hearings are traditionally viewed as venues for information gathering and oversight, they also serve as highly visible platforms for political communication. This study evaluates whether committees that devote a greater share of their hearings to high-profile witnesses exhibit lower levels of legislative effectiveness due to a potential shift toward symbolic activity. Using the Congressional Committee Hearing Dataset (CoCoHD), the analysis covers House committee hearings from the 105th through the 115th Congress. The data are aggregated to …

Tale Of Two Pharmacies, Katie R. Jadin

Honors Theses

Community pharmacists are among the most accessible healthcare providers in the United States and play an increasingly important role in improving patient outcomes. This study observes whether geographical distance and demographic differences influence patient healthcare needs within community pharmacy settings. Communities in Wisconsin and Mississippi, approximately 800 miles apart, were compared due to differences in population demographics, socioeconomic factors, and disease burden.

A survey was distributed to community pharmacy employees, including pharmacists, pharmacy interns, and pharmacy technicians, to assess common disease states, medication patterns, pharmacy workload, and patients' barriers to care. Twelve responses were collected from pharmacy employees.

Despite the …

The Impact Of Hearts For The Homeless On Students At The University Of Mississippi, Ellie Menszer

Honors Theses

Hearts for Homeless (H4H) is an international organization that works to help one of the most vulnerable populations for cardiac disease, the homeless, due to the lack of access to health care and information. At the University of Mississippi, H4H is a registered student organization that volunteers weekly at the Oxford Community Market (OXCM) to provide free blood pressure screenings and heart health information. H4H helps the community while also providing students with hands-on patient care experience. The goal of this research is to determine how volunteering with H4H impacts students at the University of Mississippi. A literature review informed …