Digital Commons Network^™

Finding Aid For The General Wirt Adams Collection (Mum00755)

Archives & Special Collections: Finding Aids (alphabetical)

Collection of papers relating primarily to the life and military career of General William Wirt Adams. Bulk of collection consists of Civil War era correspondence and documents collected in two scrapbooks by Adams following 1865.

Finding Aid For The Cultural Events Collection (Mum00547)

Archives & Special Collections: Finding Aids (alphabetical)

Collection contains programs and schedules related to cultural events at the University of Mississippi from 1907-2006.

Issue 406: November 3-21, 2022, The Local Voice

The Local Voice

No abstract provided.

Carum Carvi Modulates Acetaminophen-Induced Hepatotoxicity: Effects On Tnf-Α, Nf-Κb, And Caspases, Tahir Maqbool Mir, Muneeb U. Rehman, Mohammad Khalid Ashfaq, Wajhul Qamar

Faculty and Student Publications

Carum carvi is a well-known herb traditionally used as a spice in Asian countries. Acetaminophen is a known marketed drug mainly used as an analgesic. It has been scientifically proven that consumption of acetaminophen (paracetamol) is associated with liver toxicity if taken in high doses without medical supervision. The present study evaluated the in vivo antioxidant and hepatoprotective efficacy of Carum carvi against acetaminophen-induced hepatotoxicity in Wistar rats. Our results demonstrate that Carum carvi, at doses (mg/kg) of 100 (D1) and 200 (D2), showed inhibitory properties for DNA-sugar damage, lipid peroxidation, DPPH scavenging, and increased reducing potential in a concentration-dependent …

Rosmarinic Acid Prevents Cisplatin-Induced Liver And Kidney Injury By Inhibiting Inflammatory Responses And Enhancing Total Antioxidant Capacity, Thereby Activating The Nrf2 Signaling Pathway, Yifei Xiang, Min Ji, Liqin Wu, Li Lv

Faculty and Student Publications

Drug-induced liver and kidney damage is an emergent clinical issue that should be addressed. Rosmarinic acid (RA) has obvious anti-inflammatory and antioxidant effects, so we evaluated the anti-inflammatory and antioxidant effects of RA pretreatment on serum and liver and kidney tissues of cisplatin (CP)-treated mice and explored the possible mechanisms. The results showed that RA pretreatment effectively downregulated the serum, liver, and kidney levels of ALT, AST, BUN, and CRE and the inflammatory factors IL-1β, IL-6, and TNF-α, and simultaneously enhanced the total antioxidant capacity of the liver and kidney. RA pretreatment significantly reduced the levels of MPO, MDA, and …

Issue 405: October 20-November 3, 2022, The Local Voice

The Local Voice

No abstract provided.

Stress, Decision-Making And Reward Value: Effects Of Intermittent Social Stress On Delay Discounting Behavior, Alfonso Martinez, Alberto Del Arco

Annual Poster Session 2022

Corresponding author (Neuroscience): Alfonso Martinez, [email protected]

Issue 404: October 6-20, 2022, The Local Voice

The Local Voice

No abstract provided.

Stem Facility Construction Nears Halfway Point, Erin Garrett

University of Mississippi News

Largest academic building in university history to feature innovative lab spaces, TEAL classrooms

Dominant Frequency Extraction For Operational Underwater Sound Of Offshore Wind Turbines Using Adaptive Stochastic Resonance, Rongxin Wang, Xiaomei Xu, Zheguang Zou, Longfei Huang, Yi Tao

Faculty and Student Publications

Underwater sound generated by the rapidly increasing offshore wind farms worldwide greatly affects the underwater soundscape and may cause long-term cumulative effects on sound-sensitive marine organisms. However, its analysis and impact assessment are heavily interfered with by underwater ambient noise. In this study, an adaptive stochastic resonance method is proposed to extract the dominant frequency of wind turbine operational sound when heavy noise is present. In particular, a time–frequency–amplitude fusion index was proposed to guide the parameter tuning of an adaptive stochastic resonance system, and an equilibrium optimizer based on the physical dynamic source–sink principle was adopted to optimize the …

Hiv-1 Tat Upregulates The Receptor For Advanced Glycation End Products And Superoxide Dismutase-2 In The Heart Of Transgenic Mice, Alaa N. Qrareya, Nason S. Wise, Emmanuel R. Hodges, Fakhri Mahdi

Faculty and Student Publications

Cardiovascular disorder (CVD) is a common comorbidity in people living with HIV (PLWH). Although the underlying mechanisms are unknown, virotoxic HIV proteins, such as the trans-activator of transcription (Tat), likely contribute to CVD pathogenesis. Tat expression in mouse myocardium has been found to induce cardiac dysfunction and increase markers of endothelial toxicity. However, the role that Tat may play in the development of CVD pathogenesis is unclear. The capacity for Tat to impact cardiac function was assessed using AC16 human cardiomyocyte cells and adult male and female transgenic mice that conditionally expressed Tat [Tat(+)], or did not [Tat(−)]. In AC16 …

Immunomodulatory Effects Of Plant Extracts From Salvia Deserta Schang. And Salvia Sclarea L., Aizhan Zhussupova, Gaziza Zhumaliyeva, Vyacheslav Ogay, Assel Issabekova

Faculty and Student Publications

Medicines, their safety, effectiveness and quality are indispensable factors of national security, important on a global scale. The COVID-19 pandemic has once again emphasized the importance of improving the immune response of the body in the face of severe viral infections. Plants from the Salvia L. genus have long been used in traditional medicine for treatment of inflammatory processes, parasitic diseases, bacterial and viral infections. The aim of the current study was to evaluate the immunomodulatory effects of plant extracts LS-1, LS-2 from Salvia deserta Schang. and LS-3, LS-4 from Salvia sclarea L. plants growing in southern Kazakhstan by conventional …

The Isom Report - Fall 2022, Jaime Harker, Theresa Starkey

Isom Report

The official newsletter of the Sarah Isom Center for Women and Gender Studies.

Issue 403: September 22-October 6, 2022, The Local Voice

The Local Voice

No abstract provided.

Interactions Of Marine Sulfated Glycans With Antithrombin And Platelet Factor 4, Wenjing Zhang, Weihua Jin, Vitor H. Pomin, Fuming Zhang

Faculty and Student Publications

The molecular interactions of sulfated glycans, such as heparin, with antithrombin (AT) and platelet factor 4 (PF4) are essential for certain biological events such as anticoagulation and heparin induced thrombocytopenia (HIT). In this study, a library including 84 sulfated glycans (polymers and oligomers) extracted from marine algae along with several animal-originated polysaccharides were subjected to a structure-activity relationship (SAR) study regarding their specific molecular interactions with AT and PF4 using surface plasmon resonance. In this SAR study, multiple characteristics were considered including different algal species, different methods of extraction, molecular weight, monosaccharide composition, sulfate content and pattern and branching vs. …

Issue 402: September 8-22, 2022, The Local Voice

The Local Voice

No abstract provided.

Sustaining The Individual In The Collective: A Kantian Perspective For A Sustainable World, Zachary Vereb

Faculty and Student Publications

Individualist normative theories appear inadequate for the complex moral challenges of climate change. In climate ethics, this is especially notable with the relative marginalization of Kant. I argue that Kant's philosophy, understood through its historical and cosmopolitan dimensions, has untapped potential for the climate crisis. First, I situate Kant in climate ethics and evaluate his marginalization due to perceived individualism, interiority and anthropocentrism. Then, I explore aspects of Kant's historical and cosmopolitan writings, which present a global, future-orientated picture of humanity. Ultimately, Kant's philosophy offers a unique take on the climate deadlock capable of sustaining the individual in the collective.

Biologist, Students Promote Research On Sustainable Ecotourism, Erin Garrett

University of Mississippi News

Team leads workshop for international scientists, industry experts

Evaluating Success Factors And Challenges Among Small-Scale Agricultural Producers: A Texas Case Study, Katie Tritsch, Ken Mix, Michelle L. Edwards, Manuel Piña Jr.

Journal of Rural Social Sciences

Literature on small farms in the U.S. is limited though they are the most numerous farm type, generate over twenty percent of agricultural production, and are more likely to be operated by historically underserved (i.e., beginning, minority, veteran, women, young) farmers than large-scale farms. This article details an online survey study of small-scale agricultural producers using a purposive sample from Texas. We used cross tabulations to evaluate qualitative operational and demographic (e.g., age, gender) factors of success, finding several significant variables with moderate effect sizes. Generally, producers regarded quality of life as more important to success than profitability. Producers’ top …

Preparation, Characterization And Pharmacokinetics Of Tolfenamic Acid-Loaded Solid Lipid Nanoparticles, Wei Xu, Zhaoyou Deng, Yifei Xiang, Dujuan Zhu

Faculty and Student Publications

The clinical use of nonsteroidal anti-inflammatory drugs is limited by their poor water solubility, unstable absorption, and low bioavailability. Solid lipid nanoparticles (SLNs) exhibit high biocompatibility and the ability to improve the bioavailability of drugs with low water solubility. Therefore, in this study, a tolfenamic acid solid lipid nanoparticle (TA-SLN) suspension was prepared by a hot melt–emulsification ultrasonication method to improve the sustained release and bioavailability of TA. The encapsulation efficiency (EE), loading capacity (LC), particle size, polydispersity index (PDI), and zeta potential of the TA-SLN suspension were 82.50 ± 0.63%, 25.13 ± 0.28%, 492 ± 6.51 nm, 0.309 ± …

Physical, Chemical, And Mineralogical Controls On Retardation Of Anatoxin-A Migration By Sorption To Natural Soils With Implications For Groundwater Protection, Justin L. Hobart, Andrew M. O’Reilly, Jennifer N. Gifford

Faculty and Student Publications

Increasing prevalence of cyanotoxins in surface water bodies worldwide threatens groundwater quality when contaminated water recharges an aquifer through natural or artificial means. The subsurface fate of anatoxin-a (ATX) is not well studied. Laboratory batch experiments were performed to expand the current knowledge of ATX sorption affinities to geologic media, with a focus on natural soil (Vertisol, Ultisol, Alfisol, and Inceptisol) and physical, chemical, and mineralogical characteristics. For a range of aqueous ATX concentrations (0.3–14 μg/L), linear, Freundlich, and Langmuir isotherms fit observed data well (r2 = 0.92–1.00, RMSE = 0.4–6.3 μg/kg). Distribution coefficient (Kd) and retardation factor (Rf) values …

Develop New Art, Incorporating Augmented Reality And Animation Skills (Summer 2022), Frank Estrada

Staff Residencies

Frank Estrada is the Visual Resources Specialist and Gallery Coordinator in the Department of Art and Art History. He has been on staff at the University of Mississippi since August 6, 2018.

Photo of Frank Estrada by Bruce Newman.

Commercial Space Companies: Lawmakers Of 21st Century New Space, Hongxi Wang

Journal of Space Law

No abstract provided.

Issue 401: August 25-September 8, 2022, The Local Voice

The Local Voice

No abstract provided.

Staff Members Complete Inaugural Creative Residencies, Edwin B. Smith

University of Mississippi News

Fifteen tackle outside projects that fuel progress, plan Sept. 1 presentation for results

Issue 400: August 11-25, 2022, The Local Voice

The Local Voice

No abstract provided.

Donna Martin, Donna Martin, Institute Of Child Nutrition. Child Nutrition Archives.

Oral History Project (all interviews)

A Miami native, Donna Martin then went north to the University of Georgia for her post-secondary education. Donna ended up settling in Georgia and building a solid career there in child nutrition, picking up a strong southern accent along the way. Donna is currently the nutrition director for Burke County Public Schools.

Exploring Biology Beyond The Classroom, Staff Report

University of Mississippi News

Off-campus courses give students hands-on opportunities in biodiversity locations

Education, Society, And The K-12 Learner, University Of Mississippi. School Of Education. Department Of Teacher Education

Textbooks and Open Educational Resources

An exploration of selected components of the education profession: purpose of education. American education system, education and the legal system, child and adolescent development, and diversity.

• Part 1: Educational History and Policy
• Part 2: Educational Psychology

Comparative Single Dose Pharmacokinetics And Metabolism Of Racemic Primaquine And Its Enantiomers In Human Volunteers, Washim Khan, Yan Hong Wang, Narayan D. Chaurasiya, Np Dhammika Nanayakkara

Faculty and Student Publications

Primaquine (PQ) is a racemic drug used in treatment of malaria for six decades. Recent studies suggest that the two enantiomers of PQ are differentially metabolized in animals, and this results in different pharmacological and toxicological profiles. The current study characterizes the pharmacokinetic (PK) properties, metabolism and tolerability of the individual enantiomers of PQ in healthy human volunteers with normal glucose-6-phosphate dehydrogenase (G6PD) activity. Two cohorts (at two dose levels), each with 18 subjects, participated in three study arms in a crossover fashion: a single dose of the (−)-R enantiomer (RPQ), a single dose of the (+)-S enantiomer (SPQ), and …