Digital Commons Network^™

Dissecting The Connection Between Technological Advancement And Environmental Justice Through An International Perspective, Benson H. Le

Honors Theses

This thesis dissects the connection between technological advancement and environmental justice through an international perspective. With modern-day technologies advancing by the day, the implications of these technologies on our environment have been rising as well. This thesis looks to dissect the connection between these two entities, as well as view this connection through an international lens. Countries around the world view this connection very differently, and the way these technologies are implemented within the environment is drastically different based on different international views. This thesis aims to answer the questions about this phenomenon. How do countries around the world view …

Beyond The Bug: How The Covid-19 Pandemic Exposed Longstanding Systemic Failures In The United States Workforce And Economy, Abbey M. Markley

Honors Theses

The purpose of this thesis is to investigate and discuss how longstanding systemic failures in the United States exacerbated the effects the COVID-19 pandemic had on the American economy, essential healthcare workers, and overall public trust in institutions. A review of the existing literature surrounding this topic and the subsequent results of various studies were used to compose this thesis. The United States has a painful lack of worker protections and tends to view members of its workforce as expendable, even in times such as pandemic when they are deemed essential. Healthcare workers in particular faced increasing threats to their …

Determining The Relatedness Of Simian Varicella Virus Strains Using Polymerase Chain Reactions And Delta Herpesvirus-Dervied Primers, Ellyn M. Waits

Honors Theses

This study examines genetic variation among strains of Simian Varicella Virus (SVV) using genomic analysis. The primary goal of this experiment was to observe potential genomic differences among the Liverpool vervet virus (LVV), the Tsukuba herpesvirus, and the Delta herpesvirus (DHV) strains using primer sets developed from the fully sequenced DHV strain. SVV strains were initially cultivated in Vero cell cultures to begin viral propagation. Viral proliferation in these cell cultures enables DNA isolation via standard purification methods. The extracted viral DNA is subjected to polymerase chain reaction (PCR) amplification targeting specific regions of open reading frames (ORFs) in the …

Antibiotic Resistance Patterns In Bacterial Isolates From Mississippi Gulf Coastal Environments, Lawler F. Horn

Honors Theses

Coastal environments host diverse microbial communities that play essential ecological roles but may also serve as reservoirs for antibiotic-resistant bacteria. This study investigated patterns of antibiotic resistance in microbial isolates collected from public beaches along the Mississippi Gulf Coast. A total of 143 bacterial isolates exhibited growth and were included in antibiotic susceptibility screening. High levels of antibiotic resistance were observed, with 137 of 143 isolates showing growth on vancomycin, 124 on amoxicillin, and 102 on erythromycin. Resistance to kanamycin (19/143 isolates) and tetracycline (33/143) was less common. Multidrug resistance was widespread, with 101 isolates (70.6%) resistant to three or …

Lifestyle And Activity Patterns Of The Classic Period Maya From Chac Balam And San Juan, Ambergris Caye, Belize, Abigail L. Hornbeck

Honors Theses

Bioarchaeological research often uses skeletal remains to reconstruct patterns of activity and labor in past populations. This study examines potential sex-based differences in long bone morphology among individuals from the Classic Maya sites of Chac Balam and San Juan on Ambergris Caye, Belize. These coastal communities participated in maritime trade networks, and daily activities such as cargo transport, canoe travel, and fishing may have placed distinctive mechanical stresses on the skeleton. The goal of this study was to evaluate whether measurable differences in bone structure between males and females reflect differences in habitual activity patterns.

Two complementary methods were used …

Esports Cosmopolitan Canopy, Reice Hicks

Honors Theses

This thesis concerns the area of sociology. Specifically, it is a sociological study of a community on Ole Miss’s campus and how they form what is known within the sociology field as a “cosmopolitan canopy,” a term coined by Elijah Anderson. Using this term, I proceed to prove not only how the Ole Miss Esports club falls under this jurisdiction, but the effects of esports on the youth as a whole, both positive and negative. All of my data was extracted via literature review, online research, note-taking, visual observation, and one-on-one interviews with people involved with the club. The entire …

Quantifying Genetic Diversity In Nematode Feeding Rate, Jacob King

Honors Theses

Understanding how populations persist under changing environmental conditions is a central question in ecology and evolutionary biology. Variation in traits related to resource acquisition may play a key role in determining population survival when resources are limited or fluctuate over time. In this study, I investigated how variation in feeding-related traits influences population persistence using a combination of computational modeling and laboratory experiments. I developed a stochastic, individual-based consumer–resource model to simulate population dynamics across varying levels of trait variance and resource regimes. Across 60,000 simulated populations, increased trait variation consistently reduced extinction risk and extended persistence time, although the …

Integrating Movement In Elementary Classrooms: Teacher Perceptions And Student Benefits In A Kindergarten Setting, Ferriday R. Green

Honors Theses

Movement integration has been shown to positively influence elementary students’ cognitive performance, engagement, and on-task behavior; however, its use in classrooms remains inconsistent due to various teacher-perceived barriers. This qualitative study investigates the challenges teachers face when implementing movement integration in elementary classrooms and examines whether access to structured, movement-integrated lesson plans influences instructional practices. The study was conducted with one kindergarten teacher at Lafayette Elementary School. Data were collected through two semi-structured interviews—one conducted prior to implementation and one following a two-week intervention period during which the teacher implemented pre-developed, movement-integrated lesson plans aligned with required academic standards. Interview …

“Con Ăn Cơm Chưa?” (“Have You Eaten Yet?”): Foodways, Identity, And Generational Place-Making For Vietnamese Women In Memphis, Alana Freimanis

Electronic Theses and Dissertations

This qualitative study examines the role of food within community tactics for mobilization and negotiation. In order to do so, this study employs a mixed-methods approach of semi-structured interviews, participant observations, and archival analysis, to answer questions around how participants subvert historically racialized narratives around Vietnamese immigrant’s labor, family, and identity. Specifically, how do Vietnamese American women in Memphis use food labor to negotiate racialized immigrant identities and mobilize cultural and community power within the constraints of gendered expectations, class position, and racial stereotypes? Furthermore, this research focuses on Vietnamese women’s positionality, centering women chefs and community leaders as the …

Health And Care: Childhood Among The Classic Period Maya At Buenavista Del Cayo, Belize, Lindsey Hall

Electronic Theses and Dissertations

Three deposits of perinates, infants, and young children within two non-residential superstructures of Buenavista del Cayo, Belize, display evidence of daily maintenance and care. A total of ten subadult individuals, aged 39.4 weeks gestation to 3 years, from the archaeological site of Buenavista were recovered during 2018 excavations. Signs of care and daily maintenance include survivorship through the vulnerable neonatal period (first twenty-eight days) and transition into infancy, survivorship with potential pinprick lesions on external and internal zygomatic, parietal, and pars basilaris, and intentional maintenance of the body after death. Identification of care and daily maintenance at Buenavista informs the …

Investigating The Effects Of High- And Low-Load Resistance Training On Tendon Size, Muscle Growth, And Strength Adaptations, William Blake Hammert

Electronic Theses and Dissertations

Purpose: To examine the effects of resistance training load and a single bout of maximal strength testing on skeletal muscle growth, distal biceps brachii tendon thickness, and task-specific and non-specific strength outcomes relative to a time-matched non-exercise control group. Methods: 216 young (~21 years), non-resistance trained adults (125 females) were enrolled, with 201 (118 females) included in the final analyses. Participants were randomized to: High-Load (n=45), Low-Load (n=48), Mid-Point (n=54), or Control (n=54). High- and Low-Load completed 6 weeks of unilateral elbow flexion resistance training to task failure, Mid-Point completed a one-repetition maximum (1RM) elbow flexion test at 3-weeks, and …

The Tugaloo Effect: Preliminary Analyses Of Population Genomics And Parasitism In Salamanders Of Northeast Georgia, Tyler Lewis Brock

Electronic Theses and Dissertations

The Tugaloo River is a 50-mile-long stretch of river that serves as an important political and biogeographical boundary in far northeastern Georgia and northwestern South Carolina. The extreme topography, complex geological and hydrological history, and unique assemblage of soils, flora, and fauna of the Tugaloo region make it a prime candidate for study. I used the diverse salamander community there to conduct two studies. Study 1 investigated how the population genomics of select species in the genera Desmognathus and Plethodon were impacted by ancient drainage modifications from the Pleistocene which included not only the Tugaloo River but also the Tallulah, …

Recipe For Resistance: Oral Histories Of Queer Foodways In The Us South, Astrid Janie Knox-Mcconnell

Electronic Theses and Dissertations

This thesis examines the emerging question of what constitutes “queer food.” It asks how this concept takes on a distinct regional form in the United States South. Drawing on oral histories, archival materials, and cookbooks, it argues that queer southern foodways are not only a subset of queer food studies, but also a distinct cultural and political formation shaped by southern histories of race, labor, family, and survival. The thesis makes the case that queer southern foodways function simultaneously as protest, utopian practice, and aesthetic pleasure. Through the act of cooking, eating, and sharing food, queer southerners articulate alternative social …

Foundations And Scope Of Moral Standing, Vikas Beniwal

Electronic Theses and Dissertations

This thesis investigates the foundational grounds of moral standing. I contend that sentience, while frequently cited as the primary criterion, lacks sufficient justification when asserted as a necessary condition. I propose an alternate feature as sufficient grounds of moral standing.

April 30, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Mississippi Coastal Bacterial Community Response To Lowered Salinty, Jackson C. Sues

Honors Theses

Microbial communities are essential to the function of coastal ecosystems; however, few studies have examined their response to short-term reductions in salinity. This study used a microcosm approach to examine how decreased salinity over five days affected seawater bacterial community composition, diversity, and richness. Microcosms were assigned to three treatments: unmanipulated seawater (control) collected from the Mississippi coast, seawater amended with natural freshwater, and seawater amended with sterilized freshwater. Length of time bacteria spent in the microcosms was found to have the strongest effect on bacterial community composition, while salinity effects were weaker but still statistically significant. All treatments shifted …

Multi-Omics Systems-Guided Insights Of Withanolide And Other Bioactives Contributions To Anti-Stress And Endurance Outcomes In Withania Somnifera, Deepak Mundkinajeddu

Oxford ICSB

Conventional Ashwagandha standardization is largely focused on total withanolide quantification, without insights on the functional contribution of other phytochemical fractions. In this discovery-driven development program, orthogonal array–based model combined with predictive transcriptomics was used to delineate the relative biological roles of withanolide and other bioactive components within Withania somnifera extracts. Validated animal models showed that withanolide-enriched fractions significantly reduced serum cortisol (p< 0.05), while other bioactive-enriched fractions significantly increased run-time to exhaustion (p< 0.05), confirming anti-stress and endurance mechanisms. By linking the phytochemical profile with predicted biological pathway activity, the composition of the extract is rationally optimized for the development of a standardized extract (Ashwa.30), designed to deliver both anti-stress and endurance benefits at a dose of 30 mg. Clinical evaluation of the Ashwagandha extract demonstrated significant reductions in perceived stress scores and circulating cortisol levels, alongside measurable improvements in endurance parameters compared to placebo (p< 0.05), confirming translational alignment from preclinical discovery to human outcomes. Untargeted metabolomic profiling revealed enrichment of glycine and serine metabolism, methionine metabolism, phenylalanine and tyrosine metabolism, and homocysteine degradation pathways. These integrated metabolic changes worked together to improve energy production, support mitochondrial repair, maintain antioxidant balance, and help reset the body’s stress response system. This work presents a systems-biology–based approach to holistic Ashwagandha standardization, integrating withanolides and complementary bioactivities. It establishes a precision-driven framework for clinically validated adaptogenic efficacy.

Unmasking Ashwagandha Controversy: Safety, Toxicity, And Adulteration, Tahir Maqbool Mir

Oxford ICSB

Ashwagandha (Withania somnifera) is an adaptogenic shrub valued for its roots, which support systemic health. Increasing use has raised safety concerns about adulteration and hepatotoxicity. The roots of ashwagandha are primarily preferred for systemic health, while the leaves were traditionally reserved for topical applications to treat joint inflammation and promote wound healing.  Although generally considered safe, ashwagandha supplements have been linked to drug-induced liver injury, including cholestasis, jaundice, and pruritus. Reports from various organizations like LARB in the Netherlands indicate a rise in liver toxicity cases, possibly due to cytotoxic withafrin A and DNA-damaging withanone. A major concern is widespread …

Advancements In Botanical Toxicology, Characterization, And Regulatory Frameworks, Paula Brown

Oxford ICSB

No abstract provided.

Determinants Of Opioid-Relevant Exposure From 7-Hydroxymitragynine Products In The Evolving U.S. Marketplace, Igor Koturbash, Scott Alsbrook, George Pro

Oxford ICSB

Kratom’s U.S. market has rapidly evolved from largely botanical powders and capsules to products enriched in 7-hydroxymitragynine (7-OH), a potent mu-opioid receptor agonist that is typically present only at trace levels in leaf material. To quantify downstream behavioral health burden and contextualize it with real-world signals of product diffusion, we analyzed National Survey on Drug Use and Health (NSDUH) data (2021-2023) alongside public health alert trends and systematic online product surveillance. In NSDUH, 5.8% of adults met criteria for serious mental illness (SMI). SMI increased by 150% among adults with combined opioid use disorder (OUD) and kratom use between 2021 …

Naturally Derived Kratom Extracts: Toxicological Evaluation In Humans And Rodents, Sibyl Swift

Oxford ICSB

Peer-reviewed literature provides limited toxicological data on the consumption of naturally derived kratom extracts. Given the increasing use of kratom products, understanding their safety profile is critical for public health and regulatory decision-making. To address this gap, we conducted a rodent toxicology assessment and a controlled human clinical study. Human Clinical Study: Healthy male and female participants consumed specified kratom extracts daily for 14 consecutive days under controlled conditions. Clinical observations and biochemical markers were monitored throughout the study. Rodent Toxicology Study: Equivalent extract doses were administered to rodents for 90 days to evaluate subchronic exposure. Assessments included body weight, …

Medicinal Plants And One Health Drug Discovery: Plectranthus Abietanes As P-Glycoprotein Modulators, Patricia Rijo

Oxford ICSB

Cancer remains a major global health challenge, with multidrug resistance (MDR)—frequently driven by P-glycoprotein (P-gp) overexpression—significantly limiting the effectiveness of chemotherapy. Within a One Health perspective, Africa, home to five major medicinal biodiversity hotspots, represents an underexplored reservoir for natural products–based drug discovery. Among this rich flora, the genus Plectranthus (Lamiaceae) emerges as a particularly promising source of bioactive abietane diterpenes. In this work, the abietane diterpene 7α-acetoxy-6β-hydroxyroyleanone (Roy), isolated from Plectranthus grandidentatus Gürke, exhibited pronounced cytotoxic activity against several cancer cell lines. To enhance its pharmacological profile, a series of Roy ester derivatives was synthesized and evaluated for their …

Hazard Vs Risk: Scientific Considerations On The Eu Clp Approach To Mocs And Whole Essential Oil Classification With Tea Tree Essential Oil As An Illustrative Example, Cecile Bascoul, Dakota Carter, Joseph Dawson, Tim Valentiner, Russell J. Osguthorpe

Oxford ICSB

The ongoing revision of the EU Classification, Labelling and Packaging (CLP) Regulation represents a critical development for the essential oil industry. A provisional derogation has been introduced for plant-derived, non-chemically modified Multi-Constituent Substances (MOCS), including essential oils, following sustained advocacy efforts. However, the European Commission is required to deliver, by the end of 2029, a scientific report reassessing the validity of this derogation based on scientifically and regulatorily accepted safety evaluation approaches. In the absence of such a derogation, essential oils could be classified solely on the basis of individual constituents exceeding regulatory thresholds, irrespective of the whole oil safety …

Ginsenoside-Based Theranostic Agents For Alzheimer's Disease: Implications For Brain Penetration, Cellular Uptake, And Anti-Aging Effects, Hak Soo Choi

Oxford ICSB

Red ginseng and its bioactive constituents, ginsenosides, have long been associated with neuroprotection and anti-aging effects, yet their limited ability to cross the blood-brain barrier (BBB) and poorly characterized biodistribution have hindered therapeutic translation. To address this, we developed a library of “ginsenoprobes” by conjugating major red ginseng components (Rg1, Rg3, Rb1, Rh2, Rk1, Rg5) and red ginseng extract (RGE) to a zwitterionic near-infrared (NIR) fluorophore (ZW800-1C), enabling real-time tracking of their fate in vitro and in vivo. All ginsenoprobes were purified to >95% homogeneity via preparative HPLC and rigorously characterized for optical properties, including molar extinction coefficients and dye-to-ginsenoside …

Mississippi Day Fun Ranges From Rock Walls To Research, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – The University of Mississippi is getting ready to break out the pop-up tents again. This time, they are not for tailgating, but rather for its annual outdoor open house on April 11.

April 2, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Pharmacy Matters April 2026, University Of Mississippi School Of Pharmacy

Pharmacy Matters Newsletters

Featured stories: Ole Miss Student Pharmacist Earns Top 10 Honors in National Patient Counseling Competition, Support Ole Miss Pharmacy on Giving Day, April 14, SOP Alumni Weekend: Honoring Alumni Who Lead, Mentor, and Serve, Match Day Success, Pharmacy Team Develops 3D-printed Bandage to Help Heal Chronic Wounds, Global Botanicals Conference Adds Cancer Focus, 2026 Charles W. Hartman Memorial Lecture, Dr. Aaron E. Carroll, 2026 Ronald F. Borne Endowed Lecture, Dr. Neha Pagidipati, MD, MPH, Applied Statistics Student Research Awards, CASE Workshop Selection, Image of Research Finalist, Kenvue APhA Scholarship, Alumni Insider's View Program, NACDS Rx Impact Day on Capitol Hill, …

Who Then Can Be Saved? A Discussion Of Views Within The Christian Tradition Concerning The Salvation Of The Non-Christian, Logan A. Davis

Honors Theses

This thesis argues that, contrary to popular conception, the Christian Tradition is not strictly exclusivist in its understanding of salvation or in its assessment of the fate of the non-Christian but rather displays a rich diversity of views. Both the Christian Tradition and the Christian scriptures are characterized by a certain ambiguity on this issue; although a definitive answer may exist, it is not easily identifiable. Given this ambiguity, the study presents a representative spectrum of theological positions within the Christian Tradition and analyzes their respective treatments of the salvation of the non-Christian. In doing so, it seeks to provide …

Truth Or Consequences, Jack Galati

Yalobusha Review

No abstract provided.

Full Issue, Journal Editors

Yalobusha Review

No abstract provided.