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Articles 1861 - 1890 of 10458
Full-Text Articles in Entire DC Network
A Modernized Fairy Tale: Speculations On Technology, Labor, Politics, And Gender In The Oz Series, Zachary Hez Hollingsworth
A Modernized Fairy Tale: Speculations On Technology, Labor, Politics, And Gender In The Oz Series, Zachary Hez Hollingsworth
Honors Theses
On the surface, L. Frank Baum's Oz series would appear to merely be fourteen books of inventive children's fantasy, but in truth Baum communicates several personal progressive beliefs to his youthful audience through the use of his fantastical world upon closer examination. For my research, I reread every book in Baum's original Oz series and made note of any potentially relevant allegorical or metaphorical themes. Once I started to notice a trend of themes regarding technology, labor, politics, and gender, I settled on these themes to be the overall focus of my thesis's discussion. I read as many academic essays …
Reevaluating Religion: A Case For Inclusivity Of Lgbtq Christians In The Church, Amber Erin Dupree
Reevaluating Religion: A Case For Inclusivity Of Lgbtq Christians In The Church, Amber Erin Dupree
Honors Theses
This thesis project is focused on understanding the discrimination that is rampant amongst Southern churches regarding their LGBTQ members and offering solutions to this problem that has occurred throughout the many generations of Christianity. In order to understand this discrimination, three books were consulted for the research aspect of this project. The three books include the following: Sweet Tea by E. Patrick Johnson, Don't Be Afraid Anymore by Troy Perry, and Our Tribe by Nancy Wilson. A Questionnaire was also given to people who identified as Southern, Christian, and LGBTQ in order to gain an understanding of the current sentiments …
Cell-Free Telomere Dna As A Biomarker For Treatment Response And Tumor Burden In Glioblastoma, John P. North
Cell-Free Telomere Dna As A Biomarker For Treatment Response And Tumor Burden In Glioblastoma, John P. North
Honors Theses
Telomeres are repeated nucleotide sequences that cap the ends of each chromosome in eukaryotes. Telomeres are among the earliest genomic sequences to be degraded during apoptosis, potentially providing a biomarker of cell death. To study this, we quantified telomeres in serum from Glioblastoma and non-cancer patients. Cell-free DNA was isolated by centrifugation to remove intact cells, and purified using a QIAamp DNA Blood Midi Kit (Qiagen). Cell-free telomeric (cf-tel) and cell-free actin (cf-actin) DNA were analyzed with quantitative PCR. Total cell-free DNA was measured with PicoGreen assays. We hypothesize that patients with Glioblastoma tumors have higher cf-tel DNA levels than …
Soybeans To Chemicals: A Case Study For Undergraduate Chemical Engineering Education, Kaitlyn Myers
Soybeans To Chemicals: A Case Study For Undergraduate Chemical Engineering Education, Kaitlyn Myers
Honors Theses
The aim of this thesis is to develop a case study to reinforce the concepts that are required knowledge for chemical engineers in their sophomore year of curriculum, continuing through all of their education. The process that will be examined is the production of soybean oil, protein powder, and succinic acid from the harvest of soybeans. Further, this process will be used to align with the objectives of the chapters from the required textbook for the material balances class. The soybean industry is one of the largest in the United States agricultural sector, so it is an important real-world example …
Women In The Chilean National Identity: How Futbol And Consumption Cultures Affect The Public Sphere, Madeleine Hall Carpenter
Women In The Chilean National Identity: How Futbol And Consumption Cultures Affect The Public Sphere, Madeleine Hall Carpenter
Honors Theses
In the past thirty years, Chile has experienced dramatic political, social, economic, and cultural changes. A constant source of national identity, pride, and comfort through this tumultuous period was (and continues to be) fútbol. Chileans follow the sport relentlessly and it is a key part in the construction of local, regional, and national identities. My thesis work aims to answer the following question: how do the relationships between consumption cultures and football create/delineate/eliminate space for women in the overarching social public sphere of national belonging? In order to answer this question, I utilize a mixed methods approach to investigate how …
Personal Space: Explorations Of Environment, Surroundings, And Sense Of Place, Maggie Smith
Personal Space: Explorations Of Environment, Surroundings, And Sense Of Place, Maggie Smith
Honors Theses
This thesis is a mixed collection of prose poetry and creative nonfiction focused on the author's relationship to her surroundings and environment. The poems and essays that make up this thesis are divided into three separate sections based on a shift in environment: childhood in Madison, MS, college in Oxford, MS, and travels outside of the state of Mississippi. While much of this thesis concerns natural environment and landscape in terms of its relationship to the author, the term environment also includes relationships with friends, family and lovers, abstract environments of educational institutions like Catholic school and public university, and …
The Role Of Cannabinoids And Terpenes In Cannabis Mediated Analgesia In Rats, Margaret A. Rousseau
The Role Of Cannabinoids And Terpenes In Cannabis Mediated Analgesia In Rats, Margaret A. Rousseau
Honors Theses
Objective: This research examined the contributions of terpenes (volatile oil) and cannabinoids in cannabis mediated analgesia in rats. Methods: In experiment 1, separate groups of rats received IP administration of either vehicle, 5, 10, or 15 mg/kg cannabis extract, one of three concentrations of volatile oil alone in these cannabis extracts, one of three concentrations of these extracts with volatile oils removed, 2.5, 5, or 7.5 mg/kg Δ9-THC, or 10 or 18 mg/kg morphine 30 m before hotplate and tail-flick tests of thermal nociception. One week later, separate groups of rats received a second administration of these test articles IP …
Design And Synthesis Of Novel Cannabinoid Receptor Modulators, Mary Paige Thrash
Design And Synthesis Of Novel Cannabinoid Receptor Modulators, Mary Paige Thrash
Honors Theses
Cannabinoid (CB) receptors are validated drug targets in the endocannabinoid signaling system associated with a number of human pathologies, and the development of novel and selective small molecule CB ligands is warranted. A lead molecule HL-010, a member of the 4H-thieno[3,2-b]pyrrole-5-carboxamide class of compounds, was previously identified through CB homology modeling and virtual screening protocols as a potential high affinity ligand for cannabinoid receptors. Validation of the in silico data was realized with the evaluation of both CB1 and CB2 receptor binding and functional activity assessment: HL-010 was found to be a potent (~10 nM) and selective CB2 receptor agonist …
Cardiolipin Profiling In Metastatic Breast Cancer Cells, Meghan Houston Mcneely
Cardiolipin Profiling In Metastatic Breast Cancer Cells, Meghan Houston Mcneely
Honors Theses
Six human breast cancer cell lines (MDA-MB-231, LM, BoM, T47D, MCF7, and MCF7-BoM) were treated with three differentially targeted phospholipase inhibitors (bromoenol lactone, tricyclodecan-9-yl-xanthogenate, and halopemide) as well as various dietary oils (canola oil, avocado oil, coconut oil, olive oil, sesame oil, and soybean oil). Cell viability assays were performed to examine the effects of each inhibitor and oil in varying concentrations on the proliferation of each breast cancer cell line. The goal was to detect changes in cardiolipin concentration within each cell line after exposure to a series of various phospholipase inhibitors and oils. Liquid chromatography-mass spectrometry (LC-MS) was …
Neurotoxicity Of Asimina Triloba, Myriam Sanders
Neurotoxicity Of Asimina Triloba, Myriam Sanders
Honors Theses
Neurodegenerative diseases are thought to be brought on by genetic and environmental factors including exposure to compounds and extracts found in plants. Many substances extracted from plants have been shown to induce cell death in neurons. This experiment tests different plant compounds to determine if they induce death in neurons in cell culture. In particular, we focused on extracts and compound from the Asimina Triloba plant- a plant that had anecdotally been connected with Parkinson's Disease-like effects. Cultured neurons were treated with increasing concentrations of the compounds and extracts. Twenty-four hours after treatment, viability was assessed. Results show that while …
Effects Of Emotion And Construal Level On Obesity Stigma, Peyton D. Curtis
Effects Of Emotion And Construal Level On Obesity Stigma, Peyton D. Curtis
Honors Theses
We conducted the present study to determine how emotion and construal level contribute to obesity bias. Specifically, we examined if different emotions, such as disgust, sadness, and happiness, played a role in several different judgments of an obese versus thin individual: 1) general impressions, 2) supporting a friend, and 3) endorsing personal versus biological/environmental causes for weight. We also investigated whether a self me construal or collective we construal influenced these judgments. We additionally considered whether emotion and these construal levels would interact to influence such judgments. The current work found that emotion and construal level did not interact to …
The Construction And Characterization Of Vaccines Expressing The Pre-Membrane And Glycoprotein E Antigens Of The West Nile Virus, Ryan Johnson
Honors Theses
The West Nile Virus (WNV) is a positive polarity, single-stranded RNA virus belonging to the family Flaviviridae. In this family, there are several globally relevant human pathogens including dengue fever virus (DENV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), the newly emerging Zika virus, and the West Nile Virus (WNV). WNV, like other Flaviviruses, is spread by an arthropod vector, and can cause West Nile fever and West Nile encephalitis and meningitis, and is now considered to be endemic in Africa, Asia, Europe, the Middle East, and the United States. No vaccine is currently available to prevent WNV infection, …
Acute And Chronic Vascular Responses To Blood Flow Restriction In The Upper Body, J. Grant Mouser
Acute And Chronic Vascular Responses To Blood Flow Restriction In The Upper Body, J. Grant Mouser
Electronic Theses and Dissertations
Blood flow restriction (BFR) with low load exercise increases muscular size and strength. Little is known of vascular adaptations to this training modality, and nothing was known at very low loads. These studies examined cardiovascular responses to high load (70% of one-repetition maximum (1RM)) and very low load (15%1RM) exercise, alone or at two levels of BFR. Study 1: Participants performed unilateral biceps curls using either 15%1RM with no BFR (15/00), 40% of arterial occlusion pressure (AOP) (15/40), or 80%AOP (15/80), or 70%1RM (70/00). Systolic and diastolic blood pressure (SBP, DBP) and blood flow (BF) were measured in the arms …
Searching Through Debris: A Mass Analysis From The Carter Robinson Mound Site In Lee County, Virginia, Robert Capps
Searching Through Debris: A Mass Analysis From The Carter Robinson Mound Site In Lee County, Virginia, Robert Capps
Electronic Theses and Dissertations
The Mississippian period is one of the most widely studied periods in the prehistoric Southeast, but there are areas such as the Mississippian frontier that have not been explored in great detail. Carter Robinson is a Mississippian chiefdom located on the frontier in southwest Virginia during the thirteenth and fourteenth centuries. To better understand the people living at this site a mass analysis was conducted to examine the lithic debris left behind by the people living there. The purpose of this thesis is to identify the degree of tool production at Carter Robinson and to identify areas of tool production, …
On The Future Of Antidepressant Treatments: Targeting Neurotrophic Factors And Plasticity, Stephen W. White
On The Future Of Antidepressant Treatments: Targeting Neurotrophic Factors And Plasticity, Stephen W. White
Electronic Theses and Dissertations
For 60-plus years the explanatory model for Major Depressive Disorder (MDD) has been the monoamine theory, which states that low levels of monoamine neurotransmitters or alterations in their post-synaptic receptors are responsible for depressive symptoms. Drugs designed to elevate synaptic monoamine levels have remained the first line of pharmacotherapy prescribed by clinicians for MDD patients. However, these drugs have shortcomings. Despite evidence that current antidepressants elevate synaptic monoamine levels within hours of administration, these drugs require four to six weeks of daily administration before symptom relief appears. Furthermore, approximately half of patients taking typical antidepressants never achieve full symptom relief. …
Mechanistic In Vitro Evaluation Of Prosopis Farcta Roots Potential As An Antidiabetic Folk Medicinal Plant, Saba Feyzmand, Behzad Shahbazi, Marzieh Marami, Gholamreza Bahrami, Ali Fattahi, Yalda Shokoohinia
Mechanistic In Vitro Evaluation Of Prosopis Farcta Roots Potential As An Antidiabetic Folk Medicinal Plant, Saba Feyzmand, Behzad Shahbazi, Marzieh Marami, Gholamreza Bahrami, Ali Fattahi, Yalda Shokoohinia
Faculty and Student Publications (Open Access)
No abstract provided.
Toxicity Evaluation Of Acrylamide On The Early Life Stages Of The Zebrafish Embryos (Danio Rerio), Hattie Spencer, Joseph Wahome, Mary L. Haasch
Toxicity Evaluation Of Acrylamide On The Early Life Stages Of The Zebrafish Embryos (Danio Rerio), Hattie Spencer, Joseph Wahome, Mary L. Haasch
Faculty and Student Publications (Open Access)
No abstract provided.
Exercise And Cognitive-Related Semantic Memory Function, Paul Loprinzi, Meghan K. Edwards
Exercise And Cognitive-Related Semantic Memory Function, Paul Loprinzi, Meghan K. Edwards
Faculty and Student Publications (Open Access)
No abstract provided.
Sequential Elution Of Essential Oil Constituents During Steam Distillation Of Hops (Humulus Lupulus L.) And Influence On Oil Yield And Antimicrobial Activity, Ekaterina Jeliazkova, Valtcho D. Zheljazkov, Miroslava Kačániová, Tess Astatkie, Babu L. Tekwani
Sequential Elution Of Essential Oil Constituents During Steam Distillation Of Hops (Humulus Lupulus L.) And Influence On Oil Yield And Antimicrobial Activity, Ekaterina Jeliazkova, Valtcho D. Zheljazkov, Miroslava Kačániová, Tess Astatkie, Babu L. Tekwani
Faculty and Student Publications (Open Access)
No abstract provided.
Pharmacokinetics And Biodistribution Of Polymeric Micelles Containing Mirna And Small-Molecule Drug In Orthotopic Pancreatic Tumor-Bearing Mice, Virender Kumar, Vaibhav Mundra, Peng Yang, Yingzhe Wang, Chalet Tan, Ram I. Mahato
Pharmacokinetics And Biodistribution Of Polymeric Micelles Containing Mirna And Small-Molecule Drug In Orthotopic Pancreatic Tumor-Bearing Mice, Virender Kumar, Vaibhav Mundra, Peng Yang, Yingzhe Wang, Chalet Tan, Ram I. Mahato
Faculty and Student Publications (Open Access)
No abstract provided.
Synthesis And Evaluation Of Dual-Acting Ligands For Mu Opioid And Neuropeptide Ff Receptors, Kelsey Gabrielle Mcpherson
Synthesis And Evaluation Of Dual-Acting Ligands For Mu Opioid And Neuropeptide Ff Receptors, Kelsey Gabrielle Mcpherson
Electronic Theses and Dissertations
Pain, although subjective, is an unpleasant sensation caused by a noxious stimulus, that effects millions of people every year. Currently, the most frequently prescribed class of analgesics for moderate to severe acute and sometime chronic pain are opioid analgesics, most commonly ?-opioid receptor (MOP) agonists, such as oxycodone, morphine, and fentanyl. Although these drugs provide significant pain relief, they are also associated with unwelcome side effects such as constipation, addiction, physical dependence, respiratory depression, and physiological tolerance that leads to hyperalgesia. Receptor desensitization due to excessive receptor activation by an agonist is but one source of physiological tolerance; it can …
Freedom At The Freak Show: Carnivalesque Imagery In The Fiction Of Eudora Welty, Flannery O'Connor And Katherine Anne Porter, Virginia Mccarley
Freedom At The Freak Show: Carnivalesque Imagery In The Fiction Of Eudora Welty, Flannery O'Connor And Katherine Anne Porter, Virginia Mccarley
Electronic Theses and Dissertations
This thesis examines the function of the circus and the sideshow in the work of Eudora Welty, Flannery O’Connor, and Katherine Anne Porter, arguing that all of these authors employ Mikhail Bakhtin’s idea of the carnivalesque as a reaction to and against the expectations put on them as women who are pressured to conform to the Southern ideal. In the first chapter, I argue that Eudora Welty uses the carnivalesque to reveal the performativity of normalcy in both “Lily Daw and the Three Ladies” (1937) and “A Memory” (1937). These performances, in the first story particularly, offer a critique of …
Preparation And Evaluation Of Valacyclovir Hydrochloride Ocular Inserts By Hot Melt Extrusion Technique, Gauri Shadambikar
Preparation And Evaluation Of Valacyclovir Hydrochloride Ocular Inserts By Hot Melt Extrusion Technique, Gauri Shadambikar
Electronic Theses and Dissertations
The objective of the current study was to investigate the processability of Hot Melt Extrusion to formulate Ocular Inserts of Valacyclovir Hydrochloride and Evaluate its drug release in vitro and in vivo. Valacyclovir is the prodrug of Acyclovir, which is used in treatment of ocular keratitis and HSV infections. The bioavailability of the prodrug is better than the acyclovir and it is proved to permeate extensively through the corneal barrier. The polymer of choice was Klucel® Pharm MF and JF grades for the study. To optimize the formulation, different physical mixtures of the polymers and plasticizers (PEG 400 and Propylene …
Characterizing Variable Flow Pathways And Geochemical History Of Seepage Under The Mississippi River Levee: 2011, 2015, And 2016 Floods, Kaitlin Marie Voll
Characterizing Variable Flow Pathways And Geochemical History Of Seepage Under The Mississippi River Levee: 2011, 2015, And 2016 Floods, Kaitlin Marie Voll
Electronic Theses and Dissertations
Seepage beneath levees during flood stage becomes a concern when piping occurs, creating channels beneath the levee and forming sand boils where transported sediments discharge. Along the lower Mississippi River, pathways beneath the levee vary with surface geology, following deeper paths where the levee overlies channel fill deposits, and shallower paths where it overlies sand bar deposits. A preliminary investigation north of Vicksburg, MS, during the 2011 flood, demonstrated the potential for using aqueous geochemistry to differentiate sand boils forming at the end of deep and shallow flow pathways, though the study was limited to cation and trace metal analyses. …
Down Under Punks And Dixie Rock: Reflections On Making The Documentary Film Chinese Whispers - Southern Roots In The Australian Swampy Sound, Gretchen Labudde Wood
Down Under Punks And Dixie Rock: Reflections On Making The Documentary Film Chinese Whispers - Southern Roots In The Australian Swampy Sound, Gretchen Labudde Wood
Electronic Theses and Dissertations
No abstract provided.
Not-For-Profit Entities Industry Developments - 2018; Audit Risk Alerts, American Institute Of Certified Public Accountants (Aicpa)
Not-For-Profit Entities Industry Developments - 2018; Audit Risk Alerts, American Institute Of Certified Public Accountants (Aicpa)
Industry Guides (AAGs), Risk Alerts, and Checklists
No abstract provided.
Full Issue, Journal Editors
Junkland, K. A. Rees
Junkland, K. A. Rees
Yalobusha Review
Winner of the 2017 Barry Hannah Prize for Fiction
Role Of Natural Antioxidants From Functional Foods In Neurodegenerative And Metabolic Disorders, José Carvalho, Caio P. Fernandes, Júlio Beltrame Daleprane, Maria Silvana Alves, Didier Stien, N. P. Dhammika Nanayakkara
Role Of Natural Antioxidants From Functional Foods In Neurodegenerative And Metabolic Disorders, José Carvalho, Caio P. Fernandes, Júlio Beltrame Daleprane, Maria Silvana Alves, Didier Stien, N. P. Dhammika Nanayakkara
Faculty and Student Publications (Open Access)
No abstract provided.
Predictors Of Sun Protective Behaviors Among Latino Day Laborers, Javier Boyas, Vinayak K. Nahar
Predictors Of Sun Protective Behaviors Among Latino Day Laborers, Javier Boyas, Vinayak K. Nahar
Faculty and Student Publications (Open Access)
No abstract provided.