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Articles 991 - 1020 of 52308
Full-Text Articles in Entire DC Network
Effects Of Constant Time Delay Using Multiple Acquisition Exemplars On The Generalization Of Self-Instruction To Complete Vocational Tasks For High School Students With Intellectual Disability, Anna Norby
Theses and Dissertations--Early Childhood, Special Education, and Counselor Education
This study presents findings from a multiple probe design that evaluated the effects of constant time delay with multiple acquisition exemplars on the acquisition and generalization of self-instruction to complete vocational tasks for high school students with intellectual disability. The research included three high school students with intellectual disability, and data were analyzed across baseline, intervention, and generalization conditions. Instruction targeted the use of self-instruction procedures embedded within vocational tasks, with multiple exemplars incorporated during acquisition to promote stimulus generalization. Participants were screened using a set of pre-arranged vocational tasks to identify existing skill levels and determine appropriate instructional targets, …
Fiscal Decentralization, Foreign Capital, And Economic Development In Sub-Saharan Africa, Kwadwo D. Frempong
Fiscal Decentralization, Foreign Capital, And Economic Development In Sub-Saharan Africa, Kwadwo D. Frempong
Theses and Dissertations--Public Policy and Administration
Economic development in Sub-Saharan Africa has been shaped by two transformative policy shifts: widespread fiscal decentralization reforms transferring revenue and expenditure authority to subnational governments, and the pursuit of foreign direct investment to supplement domestic capital. Despite the breadth of these reforms, their effectiveness in promoting sustainable economic development remains empirically contested. This dissertation examines three interconnected questions about fiscal governance and capital flows in Sub-Saharan Africa: what determines the extent to which governments decentralize fiscal authority; how county fiscal composition and revenue autonomy shape subnational economic performance; and how foreign direct investment interacts with domestic investment and growth.
The …
Culturally Sustaining Pedagogy Through Popular Music And Media In Elementary Music Education, Martina Vasil
Culturally Sustaining Pedagogy Through Popular Music And Media In Elementary Music Education, Martina Vasil
Music Faculty Publications
Elementary music teachers in the United States face many challenges today, including an increasing cultural divide between teachers and students, worsening student behavior, and excessive exposure to technology in children’s lives. These challenges are magnified due to the hundreds of students elementary music teachers see weekly, the lack of teaching and planning time, and inadequate teaching resources, making it difficult to fully understand the culture and learning needs of every child. However, music educators may find culturally sustaining pedagogy (CSP) a useful tool for meeting the needs of a diverse student body. Further, when teachers engage in kid culture, the …
Review Of Current Research Describing The Influence Of Non-Health Care Drivers Of Health In Rural And Urban Populations, Katie Youngen, Julia Cecil, Tyrone F. Borders
Review Of Current Research Describing The Influence Of Non-Health Care Drivers Of Health In Rural And Urban Populations, Katie Youngen, Julia Cecil, Tyrone F. Borders
Rural & Underserved Health Research Center Publications
Social determinants of health (SDOH) (also called social drivers of health) are the conditions of the environment where people live, learn, work, and play that are known to affect health outcomes.1 The primary objective of this literature review is to summarize the most recent literature related to the Healthy People 2030 domains of a) economic stability, b) education access and quality, c) neighborhood and built environment, and d) social and community context.2 Our particular focus is on non-health care drivers of health. The secondary objective is to identify gaps in literature applied to rural populations.
Management Of Cardiovascular Disease Risk Factors By Rural And Urban Primary Care Practices, Lars E. Peterson, Zachary J. Morgan
Management Of Cardiovascular Disease Risk Factors By Rural And Urban Primary Care Practices, Lars E. Peterson, Zachary J. Morgan
Rural & Underserved Health Research Center Publications
In the United States, over 650,000 people die annually from cardiovascular disease (CVD) with high associated health care and economic costs.1 Despite a strong scientific basis for their beneficial impact on health,2 rates of preventive screening remain low.3 Levels of adherence to preventive guidelines are even lower in African American populations, socioeconomically disadvantaged populations, and underserved rural populations.4 Rural populations have higher rates of modifiable risk factors—obesity, smoking, physical inactivity—for CVD than urban populations and bear a disproportionate burden from CVD.5–7 Rates of undiagnosed and poorly treated high blood pressure are more common in rural areas.8,9 Racial/ethnic minority populations also …
Rural-Urban Differences In Dental Care Utilization After A Public Health Emergency, Quazi Minhaz Tabassum, Redwan Bin Abdul Baten, Ahmed A. Arif
Rural-Urban Differences In Dental Care Utilization After A Public Health Emergency, Quazi Minhaz Tabassum, Redwan Bin Abdul Baten, Ahmed A. Arif
Rural & Underserved Health Research Center Publications
Overview of Key Findings
• Past year dental clinic visits declined among both rural and urban populations after the COVID-19 pandemic. However, rural patients are more likely to report delayed dental service utilization than their urban counterparts.
• Participants residing in Medicaid expansion states or with health insurance coverage were 16% less likely to delay dental visits overall.
• The COVID-19 pandemic further worsened the existing challenges in dental healthcare access for urban and rural communities.
Dextromethorphan And Trace Level Detections Of Dextrorphan In Post-Race Urine Samples – A Case Report And Analysis, Kimberly Brewer, Justin C. Holmes, Clara Fenger, Abelardo Morales-Briceño, Andreas F. Lehner, George A. Maylin, Robert Holland, Levent Dirikolu, Thomas Tobin
Dextromethorphan And Trace Level Detections Of Dextrorphan In Post-Race Urine Samples – A Case Report And Analysis, Kimberly Brewer, Justin C. Holmes, Clara Fenger, Abelardo Morales-Briceño, Andreas F. Lehner, George A. Maylin, Robert Holland, Levent Dirikolu, Thomas Tobin
Maxwell H. Gluck Equine Research Center Faculty Publications
Dextrorphan is a Phase I equine metabolite of dextromethorphan, a widely used anti-tussive / cough suppressant medication marketed and available in numerous over-the-counter formulations in the United States. Dextromethorphan is an Association of Racing Commissioners International (ARCI) drug class 4 penalty class B substance and a Horseracing Integrity and Welfare Authority (HIWU) CONTROLLED S7 B substance and is regulated as such in horse racing. In horses, dextromethorphan is metabolized to its Phase I metabolite, dextrorphan, which is next glucuronidated and the resultant dextrorphan-glucuronide conjugate then excreted at remarkably high concentrations in equine urine. Dextrorphan is therefore at times identified in …
Increasing Uptake Of Diabetes Self-Management Education And Support (Dsmes) In Rural Kentucky Primary Care Clinics, Mary E. Lacy, Jessica Elliott, Vance Drakeford, Laura Wright, Brent Mckune, Key C. Douthitt, Aaron J. Kruse-Diehr, James W. Keck
Increasing Uptake Of Diabetes Self-Management Education And Support (Dsmes) In Rural Kentucky Primary Care Clinics, Mary E. Lacy, Jessica Elliott, Vance Drakeford, Laura Wright, Brent Mckune, Key C. Douthitt, Aaron J. Kruse-Diehr, James W. Keck
Epidemiology and Environmental Health Faculty Publications
Background: Diabetes self-management education and support (DSMES) is an evidence-based intervention that improves outcomes for people with diabetes, but uptake is <10%. We conducted a pilot pragmatic trial to increase DSMES in rural primary care clinics that integrated health information technology with a quality improvement (QI) learning collaborative. Methods: Two healthcare systems from rural Kentucky participated in the study. Within each system, 2 clinics received the intervention and 1 clinic served as a control (N = 6 clinics). Each intervention clinic identified a QI team (5-6 individuals) who participated in a 9-month QI learning collaborative followed by 5 months of follow-up. Our primary outcome was DSMES referrals; secondary outcomes were DSMES attendance and percentage with A1c >9%. Results: The 6 study clinics served 1,803 patients with diabetes; n = 1083 (60.1%) from 4 intervention clinics and n = 720 (39.9%) from 2 control clinics. DSMES referrals significantly increased in the intervention clinics compared to the control clinics (31.7% vs 0.1%, P < .001) and continued to increase throughout 5-month follow-up (40.0% vs 0.1%, P < .001). Conclusions: A structured QI intervention can significantly increase DSMES referral rates in primary care clinics. Findings highlight the potential of systems-level approaches to address persistent gaps in diabetes care delivery in rural settings. Clinical Trial Registry: Using Practice Facilitation and Operationalizing Referral Information Technology to Increase DSMES Utilization (Clinicaltrials.gov registration number no. NCT05472142). Clinicaltrials.gov URL (https://clinicaltrials.gov/study/NCT05472142).
The Association Between Human Papillomavirus Type 16 E6 Seroprevalence And Degrees Of Anal Disease Among Men With Hiv, Krystle A.Lang Kuhs, Christopher Otieno, Staci Sudenga, Tim Waterboer, Weiqun Tong, Dorothy Wiley, Jay H. Bream, Steven Wolinsky, Jeremy Martinson, Gypsyamber D’Souza
The Association Between Human Papillomavirus Type 16 E6 Seroprevalence And Degrees Of Anal Disease Among Men With Hiv, Krystle A.Lang Kuhs, Christopher Otieno, Staci Sudenga, Tim Waterboer, Weiqun Tong, Dorothy Wiley, Jay H. Bream, Steven Wolinsky, Jeremy Martinson, Gypsyamber D’Souza
Epidemiology and Environmental Health Faculty Publications
Introduction: Human papillomavirus type 16 (HPV16) E6 antibodies may be an early biomarker of anal cancer. We cross-sectionally evaluated when in the course of anal disease, HPV16 antibodies are induced. Methods: A nested case-control study of 846 men who have sex with men (MSM) was conducted within a prospective study of men with and without HIV. Cases of anal HPV16 (N=262), biopsy-confirmed high-grade squamous intraepithelial lesion (HSIL;N=140), and anal cancer (N=21) were individually matched to controls (N=423) on HIV status, study-participation duration, and age. Serum samples closest to diagnosis underwent HPV serologic testing; prediagnostic serial samples were tested for anal …
A Comprehensive Analysis Of Jurisdiction-Specific Laws Related To Scheduling Or Required Prescription Drug Monitoring Of Gabapentin In The United States, 2016–2024, Katherine Gora Combs, Rachel Vickers-Smith, Collin Stewart, Daniel Wacker, Juan M Hincapie-Castillo
A Comprehensive Analysis Of Jurisdiction-Specific Laws Related To Scheduling Or Required Prescription Drug Monitoring Of Gabapentin In The United States, 2016–2024, Katherine Gora Combs, Rachel Vickers-Smith, Collin Stewart, Daniel Wacker, Juan M Hincapie-Castillo
Epidemiology and Environmental Health Faculty Publications
Gabapentin prescription use has increased across the United States since the late 2000s. Concerns of potential misuse and growing overdose involvement have led to the passage of jurisdiction-specific policies targeting gabapentin prescribing; however, the current legal landscape of these policies is not well documented or understood. We conducted a comprehensive, longitudinal analysis of policies related to scheduling or required prescription drug monitoring of gabapentin across 51 jurisdictions in the United States from January 2016 through December 2024. Across the study period, 25 jurisdictions (49 %) enacted policies related to gabapentin scheduling or required prescription reporting. Eight (16 %) jurisdictions classified …
Optimizing Control Definitions In Opioid Use Disorder Genetic Research Using Electronic Health Records, Maria Niarchou, Ellen L Tsai, Mariela V Jennings, Annika Faucon, Hyunjoon Lee, Kritika Singh, Justin D Tubbs, Panos Roussos, Tian Ge, Richard C Crist, Rachel Vickers-Smith, Howard Edenberg, Amy Moore, Bradley T Webb, Eric O Johnson, Rachel L Kember, Jordan W Smoller, Lea K Davis, Brandon J Coombes, Georgios Voloudakis, David Burstein, Travis T Mallard, Vanessa Troiani, Sandra Sanchez-Roige
Optimizing Control Definitions In Opioid Use Disorder Genetic Research Using Electronic Health Records, Maria Niarchou, Ellen L Tsai, Mariela V Jennings, Annika Faucon, Hyunjoon Lee, Kritika Singh, Justin D Tubbs, Panos Roussos, Tian Ge, Richard C Crist, Rachel Vickers-Smith, Howard Edenberg, Amy Moore, Bradley T Webb, Eric O Johnson, Rachel L Kember, Jordan W Smoller, Lea K Davis, Brandon J Coombes, Georgios Voloudakis, David Burstein, Travis T Mallard, Vanessa Troiani, Sandra Sanchez-Roige
Epidemiology and Environmental Health Faculty Publications
Amidst the opioid crisis, understanding the genetic basis of opioid use disorder (OUD) is crucial for identifying biological mechanisms and intervention points. However, genome-wide association studies (GWASs) have been hampered by inadequate sample sizes and often the use of control populations not assessed for prior opioid exposure. Because opioid exposure is a prerequisite for the development of OUD, consideration of exposure history in controls is important. Electronic health record data (EHR) paired with genomic information allow a broader sampling of patients with OUD and exposed controls. We leveraged data across two healthcare systems to evaluate the impact of using controls …
Shaping The Future Of Human Biomonitoring (Hbm), Maryam Zare Jeddi, Nancy B. Hopf, Karen S. Galea, Kate Jones, Henriqueta Louro, Maria João Silva, Adrian Covaci, Tiina Santonen, Paul T.J. Scheepers, Susana Viegas, Lesliam Quirós-Alcalá, Asif Qureshi, M. Elizabeth Marder, Natalie Von Goetz, Konstantinos M. Kasiotis, Kyriaki Machera, Ovnair Sepai, Radu Corneliu Duca, Manosij Ghosh, An Van Nieuwenhuyse, Ming Kei Chung, Jihyon Kil, Shoji F. Nakayama, Aziza Menouni, Kaoutar Chbihi, Ana Maria Vekic, Gustavo Souza, Maisarah Nasution Waras
Shaping The Future Of Human Biomonitoring (Hbm), Maryam Zare Jeddi, Nancy B. Hopf, Karen S. Galea, Kate Jones, Henriqueta Louro, Maria João Silva, Adrian Covaci, Tiina Santonen, Paul T.J. Scheepers, Susana Viegas, Lesliam Quirós-Alcalá, Asif Qureshi, M. Elizabeth Marder, Natalie Von Goetz, Konstantinos M. Kasiotis, Kyriaki Machera, Ovnair Sepai, Radu Corneliu Duca, Manosij Ghosh, An Van Nieuwenhuyse, Ming Kei Chung, Jihyon Kil, Shoji F. Nakayama, Aziza Menouni, Kaoutar Chbihi, Ana Maria Vekic, Gustavo Souza, Maisarah Nasution Waras
Epidemiology and Environmental Health Faculty Publications
Human biomonitoring (HBM) continues to play an indispensable role within exposure science, offering insights into aggregate chemical exposures across populations and life stages. Since 2018, the European chapter of the International Society of Exposure Science Human Biomonitoring Working Group (ISES Europe HBM WG) has aimed to facilitate generation of more and high-quality HBM data. The working group aims to strengthen integration of HBM data into regulatory frameworks through improved study design, harmonized methodologies, and enhanced reporting practices. Key achievements in the past seven years include the harmonization of HBM metadata through development of minimum information requirements for HBM (MIR-HBM), development …
Association Between Educational Attainment And Discharge Disposition Following Incident Stroke Hospitalization, Ning Li, Erin L. Abner, Silvia Koton, Lena Mathews, Kunihiro Matsushita, Anna Kucharska-Newton
Association Between Educational Attainment And Discharge Disposition Following Incident Stroke Hospitalization, Ning Li, Erin L. Abner, Silvia Koton, Lena Mathews, Kunihiro Matsushita, Anna Kucharska-Newton
Epidemiology and Environmental Health Faculty Publications
Background – The relationship between educational attainment and discharge disposition after stroke hospitalization remains unclear. This study examined whether educational attainment is associated with discharge disposition after incident stroke and whether stroke severity modifies this association. Methods – The study included Atherosclerosis Risk in Communities (ARIC) participants with an incident stroke hospitalization from 1991 to 2020 who were enrolled in fee-for-service (FFS) Medicare at discharge. Discharge disposition was obtained from hospitalization claims. Educational attainment was categorized as “less than high school” vs. “high school or more.” Multivariable logistic regression models were used to estimate associations between educational attainment and discharge …
Building The Ryan White Hiv/Aids Program Bench In Kentucky, Lauren Bifulco, Kathleen Harding, Jana Collins, Anna Rogers, Lenon Farkash, Marwan Haddad, Alice Thornton
Building The Ryan White Hiv/Aids Program Bench In Kentucky, Lauren Bifulco, Kathleen Harding, Jana Collins, Anna Rogers, Lenon Farkash, Marwan Haddad, Alice Thornton
Epidemiology and Environmental Health Faculty Publications
The Ryan White HIV/AIDS program (RWHAP) is governed by legislative and programmatic guidelines that ensure comprehensive services are provided to persons with HIV (PWH) across the United States. Comprehensive training and skill building opportunities for programmatic staff are rare. RWHAP funding recipient organizations may struggle to acquire and retain essential program-specific knowledge, with downstream impact on patient care and treatment. We designed a comprehensive 11-session videoconference learning series to improve program staff’s confidence and competence with RWHAP fundamentals. Quantitative pre-vs-post session data were analyzed using Wilcoxon Signed-Rank tests, and qualitative data using thematic analysis. We enrolled 136 staff from 23 …
Decreased Gabapentin Prescription Fills Among Medicaid Enrollees Following State-Level Schedule V Controlled Substance Classification In Kentucky And West Virginia, Katherine Gora Combs, Stephen W. Marshall, Rachel Vickers-Smith, Alan Kinlaw, Nabarun Dasgupta, Juan M. Hincapie-Castillo
Decreased Gabapentin Prescription Fills Among Medicaid Enrollees Following State-Level Schedule V Controlled Substance Classification In Kentucky And West Virginia, Katherine Gora Combs, Stephen W. Marshall, Rachel Vickers-Smith, Alan Kinlaw, Nabarun Dasgupta, Juan M. Hincapie-Castillo
Epidemiology and Environmental Health Faculty Publications
Background: Driven by concerns of gabapentin misuse and other harms, Kentucky (KY) and West Virginia (WV) became the first states to classify gabapentin as a schedule V controlled substance in July 2017 and June 2018, respectively. This study examined the association of these policies with gabapentin utilization among Medicaid beneficiaries. Methods: Using a controlled interrupted time series design, we modeled a segmented generalized least squares regression and calculated the immediate and trend changes of gabapentin prescriptions among Medicaid enrollees in 2 states (KY, WV), separately. North Carolina (NC) was used as a control to account for secular changes; there was …
Signals Of Venous Thromboembolism Risk From Drug–Drug Interactions Involving Benzodiazepines And Other Sedative Hypnotics, Fengge Wang, Lin Chieh Meng, Kacie Bogar, Colleen M. Brensinger, Warren B. Bilker, Sascha Dublin, Todd E.H. Hecht, John R. Horn, Daniela C. Moga, Michael E. Thase, Brian L. Vanderbeek, Charles E. Leonard
Signals Of Venous Thromboembolism Risk From Drug–Drug Interactions Involving Benzodiazepines And Other Sedative Hypnotics, Fengge Wang, Lin Chieh Meng, Kacie Bogar, Colleen M. Brensinger, Warren B. Bilker, Sascha Dublin, Todd E.H. Hecht, John R. Horn, Daniela C. Moga, Michael E. Thase, Brian L. Vanderbeek, Charles E. Leonard
Epidemiology and Environmental Health Faculty Publications
Background and Objective: Benzodiazepines and sedative hypnotics such as zolpidem (“z-drugs”) are commonly prescribed for anxiety and sleep disorders. Epidemiologic evidence links their use to increased risk of venous thromboembolism. We investigated venous thromboembolism risk among concomitant users of individual benzodiazepines/z-drugs (examined separately) with other prescription medications to generate data-driven hypotheses about drug interactions resulting in clinically meaningful harm to inform future etiologic studies of specific drug combinations. Methods: We conducted a series of self-controlled case series studies within a 50% random sample of US Medicaid and Medicare data. Each cohort comprised person-time exposed to a benzodiazepine/z-drug, dichotomized into focal …
Nutrient-Driven Transcription Factor-Dna Interactions And Their Signaling Mechanisms In Metabolic Disease, Evelyn A. Bates
Nutrient-Driven Transcription Factor-Dna Interactions And Their Signaling Mechanisms In Metabolic Disease, Evelyn A. Bates
Theses and Dissertations--Nutritional Sciences
Metabolic homeostasis is maintained through tightly coordinated signaling networks that integrate diverse physiological inputs. Central to this regulation are transcription factors, which sense nutrient, hormonal, and vitamin-derived signals and translate them into coordinated gene expression programs. Transcription factor activity is governed by DNA binding, recruitment of coregulatory proteins, and interactions with specific response elements in gene promoters, which allows them to selectively modulate diverse metabolic pathways. Owing to their multifactorial and tunable nature, transcription factors have emerged as promising targets for the treatment and diagnosis of metabolic diseases, including metabolic dysfunction-associated steatotic liver disease (MASLD). This dissertation explores the molecular …
Autologous Peripheral Nerve Tissue Grafts Implanted Into The Nucleus Basalis Of Meynert And Substantia Nigra At The Time Of Bilateral Deep Brain Stimulation In Parkinson Disease: A Report Of 2 Cases, Samuel R. Daly, Jorge E. Quintero, Lisa M. Koehl, Elizabeth Roslyn Wallace, Zain Guduru, Julie A. Gurwell, Tripp Hines, Jaimie Hixson, Saad Hulou, John T. Slevin, Frederick A. Schmitt, Greg A. Gerhardt, Craig G. Van Horne
Autologous Peripheral Nerve Tissue Grafts Implanted Into The Nucleus Basalis Of Meynert And Substantia Nigra At The Time Of Bilateral Deep Brain Stimulation In Parkinson Disease: A Report Of 2 Cases, Samuel R. Daly, Jorge E. Quintero, Lisa M. Koehl, Elizabeth Roslyn Wallace, Zain Guduru, Julie A. Gurwell, Tripp Hines, Jaimie Hixson, Saad Hulou, John T. Slevin, Frederick A. Schmitt, Greg A. Gerhardt, Craig G. Van Horne
Neurosurgery Faculty Publications
Background and Objectives: Cholinergic degeneration in the nucleus basalis of Meynert (NBM) is implicated in the cognitive impairment seen in Parkinson disease (PD) and is being examined as a potential therapeutic target. We have previously shown the safety of delivering investigational autologous cell-based therapy, ie, peripheral nerve tissue (PNT), to the substantia nigra (SN) at the time of deep brain stimulation (DBS) surgery in PD (DBS-Plus). In this study, we assessed the safety and feasibility of simultaneously delivering that PNT to both the NBM and SN at the time of DBS.
Methods: Two patients with idiopathic PD and mild cognitive …
Structured Laser Vision-Based Measurement Of Gta-Weld Pool, Gang Zhang, Jianbo Wang, Yu Shi, Ding Fan, Yuming Zhang
Structured Laser Vision-Based Measurement Of Gta-Weld Pool, Gang Zhang, Jianbo Wang, Yu Shi, Ding Fan, Yuming Zhang
Electrical and Computer Engineering Faculty Publications
The current study of weld pool fluid dynamics in arc welding focuses on the numerical model establishment and simulation, and the x-ray combined with particle trace imaging observations, there is no real-time monitor and quantitatively characterize the weld pool flow behavior in welding process for controlling the weld quality. This study develops an innovative structured laser vision-based sensing system for three-dimensional (3D) reconstruction and quantitative analysis of weld pool surface topographies in gas tungsten arc welding (GTAW). Through characterization of dynamic weld pool morphologies, two novel parameters are proposed: the surface convexity variation rate (Rh) and fluid …
Changes In Telehealth Usage Among Medicaid Beneficiaries With Mental Illnesses In A Rural State: An Analysis Of Kentucky Medicaid Dataset Over 5 Years (2018–2022), Chizimuzo T.C. Okoli, Tianyi Wang, Bassema Abufarsakh, Sarret Seng, Zainab Almogheer, Jarrah Al-Kayed, Pooja Bhattarai, Holly Stith, Andrew Makowski
Changes In Telehealth Usage Among Medicaid Beneficiaries With Mental Illnesses In A Rural State: An Analysis Of Kentucky Medicaid Dataset Over 5 Years (2018–2022), Chizimuzo T.C. Okoli, Tianyi Wang, Bassema Abufarsakh, Sarret Seng, Zainab Almogheer, Jarrah Al-Kayed, Pooja Bhattarai, Holly Stith, Andrew Makowski
Nursing Faculty Publications
Introduction: Accessing mental health care remains challenging for Medicaid beneficiaries with mental illnesses (MI) in rural settings. The COVID-19 pandemic prompted telehealth service expansion through temporary policy changes and shifts in health care delivery. Despite the increased availability of telehealth as a modality to address disparities in health care access, telehealth adoption and associated use are inadequately explored among Medicaid beneficiaries with MI in Kentucky.
Objective: To examine trends and factors associated with telehealth use by residence status among Kentucky Medicaid beneficiaries with MI.
Design: A retrospective analysis of Kentucky Medicaid claims data obtained from 174,354 beneficiaries aged 18 years …
Ceo Compensation Changes Following Acquisitions, Leonce Bargeron, David J. Denis
Ceo Compensation Changes Following Acquisitions, Leonce Bargeron, David J. Denis
Finance and Quantitative Methods Faculty Publications
We find that CEO compensation increases following acquisitions only in those deals in which acquirer stock is used as the method of payment. These compensation increases are driven by increases in equity-based compensation and are concentrated in riskier acquirers, in riskier acquisitions, and in acquirers whose CEOs have low exposure to the stock price. We find little support for traditional agency cost explanations of changes in CEO pay following acquisitions. However, our findings are broadly consistent with compensation changes representing a contracting solution to a two-sided adverse selection problem that is present only in stock acquisitions.
Carbon Source-Induced Changes In The Transcriptional Landscape Of Novacetimonas Hansenii, Bashir A. Akhoon, Jordan Corley, Jia W. Tan, Roberta Magnani, Rachel R. Schendel, Andrew Lipton, Carlos M. Rodriguez Lopez, Kendall R. Corbin
Carbon Source-Induced Changes In The Transcriptional Landscape Of Novacetimonas Hansenii, Bashir A. Akhoon, Jordan Corley, Jia W. Tan, Roberta Magnani, Rachel R. Schendel, Andrew Lipton, Carlos M. Rodriguez Lopez, Kendall R. Corbin
Horticulture Faculty Publications
Novacetimonas hansenii is a model organism for bacterial cellulose (BC) production, a biopolymer with broad industrial applications. To better understand its carbon source-dependent metabolism, we conducted the first time-resolved transcriptomic analysis of N. hansenii ATCC 23769 grown on five carbon sources (glucose, fructose, mannitol, galactose, and sucrose) across five time points (24–120 h). Glucose, fructose, and mannitol supported growth and efficient BC production, whereas galactose and sucrose resulted in poor yields, likely due to limited transport and enzymatic capacity. Solid-state NMR revealed that cellulose crystallinity and polymorphism were carbon source-dependent, with reduced bcsD expression correlating with lower crystallinity. Transcriptomic profiling …
A 725-Bp Quadruple Repeat In The Promoter Of Smmyb113 Is Associated With Light-Independent Anthocyanin Regulation In Eggplant, Zhilei Xia, Meng Yang, Yinggemei Huang, Bingxin Yu, Tingxia Wan, Duanhua Wang, Qian Li, Manoj Sapkota, Shuangshuang Yan, Bihao Cao, Zhengkun Qiu
A 725-Bp Quadruple Repeat In The Promoter Of Smmyb113 Is Associated With Light-Independent Anthocyanin Regulation In Eggplant, Zhilei Xia, Meng Yang, Yinggemei Huang, Bingxin Yu, Tingxia Wan, Duanhua Wang, Qian Li, Manoj Sapkota, Shuangshuang Yan, Bihao Cao, Zhengkun Qiu
Horticulture Faculty Publications
Eggplant exhibits a diverse range of fruit colors, making it an excellent model for studying fruit pigmentation and its genetic regulation. While genes responsible for green and photosensitive purple fruit have been identified, the genetic basis of the nonphotosensitive (NPS) fruit trait in eggplant has remained elusive. In this study, we characterized a major quantitative trait locus (QTL), SmNPS10.1, on chromosome 10 using QTL-seq. By combining linkage-based gene mapping with progeny testing, we fine-mapped SmNPS10.1 to a 33.58-kb interval, within which we identified SmMYB113, an R2R3-MYB transcription factor that regulates anthocyanin biosynthesis, as the candidate gene. Sequence analysis …
Cannabis Retail Environment And Treatment For Cannabis Use Disorder, Jeremy Mennis, J. Douglas Coatsworth, Nikola Zaharakis, Nathaniel R. Riggs, Aaron Brown
Cannabis Retail Environment And Treatment For Cannabis Use Disorder, Jeremy Mennis, J. Douglas Coatsworth, Nikola Zaharakis, Nathaniel R. Riggs, Aaron Brown
Social Work Faculty Publications
Purpose: This research investigates whether the efficacy of a digital cannabis use disorder (CUD) treatment for young adults (age 18–25) differs by exposure to cannabis retailers in the residential neighborhood and activity space (significant places visited throughout daily life).
Methods: This is a secondary analysis of data from a randomized clinical trial of the digital substance use disorder treatment Peer Network Counseling-txt (PNC-txt) for reducing cannabis use among young adults with CUD ( n = 425). We hypothesize that the indirect effect of treatment on reducing cannabis use via the mediating mechanism readiness-to-change is moderated by exposure to cannabis retailers, …
Trade-Offs In Avian Parental Care, Rebekah A. Mckinnon, Malgorzata Lagisz, Sheeraja Sridharan, David F. Westneat, Kimberley J. Mathot
Trade-Offs In Avian Parental Care, Rebekah A. Mckinnon, Malgorzata Lagisz, Sheeraja Sridharan, David F. Westneat, Kimberley J. Mathot
Biology Faculty Publications
The selective forces shaping parental care have been studied for over 50 years. While theoretical and experimental work has yielded qualitative progress, the large body of empirical work testing predictions about parental investment based on life-history trade-offs has yet to be synthesized. We first provide an overview of the core life-history theory exploring how selection might shape parental care. We then conduct a systematic review and meta-analysis on studies that experimentally manipulated brood size in birds, a widely used experimental approach to manipulate parental investment. We extracted 313 estimates from 62 studies representing 31 species of birds from 19 different …
Her9 Is Required For The Migration, Differentiation, And Survival Of Neural Crest Cells, Cagney E. Coomer, Sumanth Manohar, Evelyn M. Turnbaugh, Ann C. Morris
Her9 Is Required For The Migration, Differentiation, And Survival Of Neural Crest Cells, Cagney E. Coomer, Sumanth Manohar, Evelyn M. Turnbaugh, Ann C. Morris
Biology Faculty Publications
Neural crest cells (NCC) are vertebrate-specific multipotent progenitor cells that arise from the neural plate border and go on to contribute to a wide variety of morphological structures such as the jaw and palate, enteric nervous system (ENS), and pigment cells. Defects in essential steps in neural crest cell development have been associated with a wide variety of congenital disorders, collectively referred to as neurocristopathies. Her9/Hes4 is a bHLH-O transcriptional repressor that has been shown to regulate neural crest cell and craniofacial development in Xenopus and zebrafish, however the extent of Her9 function in other neural crest cell lineages has …
Widespread Evolution Of Poricidal Flowers, Avery Leigh Russell, Rosana Zenil-Ferguson, Stephen L. Buchmann, Diana D. Jolles, Ricardo Kriebel, Mario Vallejo-Marín
Widespread Evolution Of Poricidal Flowers, Avery Leigh Russell, Rosana Zenil-Ferguson, Stephen L. Buchmann, Diana D. Jolles, Ricardo Kriebel, Mario Vallejo-Marín
Biology Faculty Publications
The evolution of tube-like floral morphologies that control pollen release via small openings (functionally poricidal flowers) represents a taxonomically and geographically widespread instance of repeated and independent evolution of a functionally similar morphology. Poricidal flowers are also often closely associated with buzz pollination by bees. Yet we lack an updated angiosperm-wide survey of their phylogenetic distribution. We identify all known angiosperm genera containing poricidal flowers via a literature survey. We determined their phylogenetic distribution and minimum number of independent gains and losses via a species-level angiosperm-wide phylogeny. We estimated if evolution of poricidal flowers is associated with changes in speciation/extinction …
Economic Exchange And Relational Work In Doubled-Up Households, Hope Harvey
Economic Exchange And Relational Work In Doubled-Up Households, Hope Harvey
Sociology Faculty Publications
Doubling up, or sharing a home, is an increasingly common way that families make ends meet. Drawing on over 170 in-depth interviews with 60 parents, I ask how doubled-up household members understand and contest their economic relationships. I show that the success of intra-household economic exchange depends not only on the amounts exchanged, but also the shared meanings behind these exchanges. Given the lack of institutionalized expectations guiding doubled-up household relationships, household members draw on competing norms, framing the household as either a solidarity unit or a series of independent nuclear family units. Although disagreement over economic relationships is common, …
Perceived Adolescent Insecure Attachment With Mothers And Fathers, Helena Pipová, Martin Dolejš, Jaroslava Suchá, Alexander T. Vazsonyi
Perceived Adolescent Insecure Attachment With Mothers And Fathers, Helena Pipová, Martin Dolejš, Jaroslava Suchá, Alexander T. Vazsonyi
Sociology Faculty Publications
The aim of this study was to test relationships between adolescent insecure attachment (anxious and avoidant) with mothers and fathers and three outcomes: food addiction, eating disorders, and weight status, in a large multi-regional sample of Czech adolescents. Anonymous, self-reported data were collected from 3,677 adolescents (1,688 boys, 45.9% and 1,989 girls, 54.1%). Both anxious and avoidant attachment with mothers were positively associated with food addiction (p <.001) and eating-disorder risk (p <.001). Importantly, avoidant attachment with fathers uniquely and additively explained variance in both food addiction (p <.001) and eating-disorder risk (p =.003), after controlling for maternal attachment. Weight status was unrelated to attachment and was predicted by sex and parental education only. Study findings highlight the salience of insecure attachment with both mothers and fathers for food addiction and eating disorders among adolescents and identify the parental relationship as a key potential preventative strategy.
“Policymakers Need To See This!”, Ramona G. Olvera, Peter Balvanz, Owusua Yamoah, Kesla Klingler, Marisa D. Booty, Sylvia A. Ellison, Amy Farmer, Amy K. Kuntz, Hilary L. Surratt, Carrie B. Oser, Margaret L. Mcgladrey
“Policymakers Need To See This!”, Ramona G. Olvera, Peter Balvanz, Owusua Yamoah, Kesla Klingler, Marisa D. Booty, Sylvia A. Ellison, Amy Farmer, Amy K. Kuntz, Hilary L. Surratt, Carrie B. Oser, Margaret L. Mcgladrey
Sociology Faculty Publications
The use of Photovoice methods to identify and address public health challenges has evolved since this participatory action research method’s inception in the 1990s. However, there is a notable lack of research on the dissemination of Photovoice findings to promote community action and change. This study evaluates audience and Photovoice participants’ experiences of dissemination events presenting the results of 21 Photovoice projects that supplemented the HEALing Communities Study (HCS), a multistate community-based study of strategies to reduce opioid overdose deaths. The Photovoice projects captured the perspectives of people with lived experience of substance use disorder and front-line providers regarding their …