Digital Commons Network^™

Valorizing Municipal Solid Waste For Sustainable Aviation Fuel And Polyhydroxyalkanoate Bioplastics: Pyrolysis And Microbial Pathways, Emon Das

Theses and Dissertations--Biosystems and Agricultural Engineering

The escalating global burden of municipal solid waste (MSW), projected to reach 3.88 billion tons annually by 2050, calls for innovative valorization strategies to mitigate environmental impacts and promote a circular bioeconomy. This thesis investigates the conversion of MSW into two high-value products: sustainable aviation fuel (SAF) and polyhydroxyalkanoate (PHA) bioplastics. Chapter one presents comprehensive physicochemical characterization and pyrolysis-GC/MS analysis of MSW feedstocks. The physicochemical results reveal that densification enhances handling and storage properties, while pyrolysis-GC/MS analysis indicates that plastic-rich MSW streams produce bio-oils with favorable hydrocarbon profiles suitable for SAF production, potentially contributing to decarbonization efforts in the aviation …

An Exploration Of Ibdp Coordinator Leadership In Southeastern U.S. Public High Schools, Raymond W. Scheetz Jr.

Theses and Dissertations--Educational Leadership Studies

Along with its brand, vision, and curricula, International Baccalaureate (IB) provides member schools with requirements and expectations, such as implementing a program coordinator. However, the need for flexibility that would allow for global implementation leaves the nature of IB’s required program coordinator positions subject to local discretion in many ways. However, while increasing in numbers globally, IB Diploma Programs are still not widely implemented in public high schools throughout the U.S. Southeast. As a result, the position of an IBDP coordinator is unusual in such schools in the region. Also, the IBDP coordinator position has not been substantially defined or …

How Elementary Schools Support Families In Mandatory Middle School Choice: A Comparative Case Study, Eleni Filippatos

Theses and Dissertations--Educational Leadership Studies

This dissertation examines the role of New York City elementary school leaders in shaping fifth graders' middle school choice processes in two public schools serving predominantly economically disadvantaged, Latino families. As school choice increasingly influences students' academic trajectories, understanding how leaders engage families in this decision-making process is essential for promoting educational equity. The study explored how public elementary school principals, counselors, and teachers support families during the universal middle school application process.

Using a qualitative comparative case study design, I conducted semi-structured interviews, field observations, and document analysis to compare leadership practices at two demographically similar elementary schools with …

Empowering Future Educators: Exploring Preservice Elementary Teachers’ Self-Efficacy Within Integrated Stem Experiences In A Science Methods Course, Shane C. Campbell

Theses and Dissertations--Education Sciences

There is an ongoing need for preparing high-quality preservice elementary teachers who are confident and capable in the design and delivery of integrated STEM instruction. This qualitative study examines the experiences of a small cohort of preservice elementary teachers enrolled in a science teaching methods course and further examines how preservice teachers' perceptions of self-efficacy change as a result of their participation in integrated STEM experiences in science methods coursework. Data were collected using pre and post surveys to capture self-reported efficacy levels related to STEM teaching, along with semi-structured interviews conducted before and after the course to further contextualize …

Smart Qos-Aware Resource Management For Edge Intelligence Systems, Minoo Hosseinzadeh

Theses and Dissertations--Computer Science

There are several definitions for Smart Cities. One common key point of these definitions is that smart cities are technologically advanced cities which connect everything in a complex urban environment including infrastructure, information, and even people to cope with the crucial problems linked with the urban life such as traffic, pollution, city crowding, health, and poverty. Central to this vision are the Internet of Things (IoT) and Big Data, where interconnected devices with sensors collect vast amounts of data for informed decision-making. However, the rapid expansion of IoT devices challenges efficient data processing while meeting diverse Quality-of-Service (QoS) requirements; for …

Tiered Coalition Formation Game Variants, Stability, And Simulation, Nathan Arnold

Theses and Dissertations--Computer Science

Tiered coalition formation games (TCFGs) have been proposed for modeling the ordering of power in intransitive structures. Furthering our understanding of the usefulness of this concept requires a close examination of this game and its variants, as well as the delineation between stability concepts and methods of finding stable outcomes. Derived from a simulation of the performance of characters in the games Pokémon Red and Blue Versions, we present an approximation of its power structure found via machine learning. We compare our findings to the community consensus ranking presented on a fan-run website, and further comment on the stability of …

Temporal Team Formation Games With Dynamic Preferences, Cameron Egbert

Theses and Dissertations--Computer Science

In the professional world, it is imperative for management entities to allocate their human resources to a work schedule, and such models of coalition formation games are well-studied. However, most existing literature only considers coalition formation in the context of a single moment in time, without accounting for changing preferences among individuals as they work together. The primary contribution of this thesis is a new team formation game that incorporates skill-based team formation and a dynamic variant of Additively Separable Hedonic Games. These Temporal Team Formation Games with Dynamic Preferences (TTFG-DPs) allow for two psychologically common preference dynamics: a preference …

Optimization, Machine Learning, And Networking Solutions For Cyber-Physical Systems, Xu Tao

Theses and Dissertations--Computer Science

Cyber-Physical Systems (CPS) represent a transformative paradigm that integrates sensing, computation, and actuation through networked systems to enable intelligent, context-aware applications across various domains. Despite their growing potential, CPS still face critical challenges, particularly in maintaining reliable, low-latency communication and efficient data processing in resource-constrained and dynamic environments. These challenges are further magnified in rural or remote deployments, where traditional network infrastructure is often unavailable or unreliable. This dissertation addresses these challenges through the development of optimization and inference algorithms that enhance network performance in Software-Defined Networks (SDN), using techniques such as reinforcement learning and network tomography for efficient routing. …

Development Of Software For Genetic Distances, Genotyping, And Phylogenetics Using Rna-Seq Data, Andrew C. Tapia

Theses and Dissertations--Computer Science

This dissertation concerns a new application of RNA-seq data—computation of pairwise genetic distance matrices. RNA-seq captures sequences of RNA molecules in some cells or tissues of interest. RNA-seq provides data are well-suited to studies examining gene expression, and its use for this purpose is currently widespread. A pairwise genetic distance matrix, the main topic of this dissertation, quantifies differences in the genomes of every pair of samples (e.g., individuals) in a given set. Genetic distance matrices are versatile; they can be used for various kinds of downstream analyses, including genotyping, phylogenetics, and genetic diversity measurement. Although DNA sequence data are …

Information-Theoretic Methods For Efficient Training And Robust Evaluations In Self-Supervised Learning, Oscar Skean

Theses and Dissertations--Computer Science

Self-supervised learning (SSL) has become a cornerstone of modern machine learning, offering a scalable alternative to costly human annotation by constructing pretext tasks directly from raw data. While SSL has delivered strong results across vision, language, and multimodal domains, two major limitations persist: (1) SSL methods are often significantly slower to train than supervised counterparts, and (2) evaluation protocols remain narrow, with most studies relying on linear probing accuracy on the pretraining dataset. . These challenges are particularly acute for large language models (LLMs), where training costs and interpretability of intermediate representations are critical concerns.

In this work, we propose …

Covid-19 Impacts On Refugee-Serving Ngos In Clarkston And The Atlanta Metropolitan Area, Georgia, United States, Ghazal Khaksari

Theses and Dissertations--Anthropology

This study provides a unique anthropological perspective on how technology, language, NGO staff, and culture intersect during emergency times, which can affect NGOs’ abilities to reach and help communities. Findings of this study emphasize the importance of equality in digital access and of available and culturally competent interpreters in reducing the gap between NGOs and refugee communities. The digital divide has played a fundamental role during the pandemic, often leading to other problems for both NGOs and refugees. This issue has taken a variety of forms in terms of access to education, language classes, community cohesion, and communication with and …

Communities Of Stone Toolmakers Along The Lower Cumberland And Tennessee Rivers, Vanessa N. Hanvey

Theses and Dissertations--Anthropology

Concurrently occupied between circa 8,600-8,200 cal B.P., the Canton (15Tr1), Lawrence (15Tr33), Morrisroe (15Lv156), and Whalen (15Ly48) sites have similar stone tool assemblages. Though the sites are situated close to one another within the lower Tennessee and Cumberland River watersheds, the connection between the people who occupied each site remains unclear. Extensive lithic deposits representing all stages of tool manufacture were identified at both the Canton and Lawrence sites, and previous lithic analyses show that similar raw materials were being accessed by stone toolmakers at all four sites. To investigate the relationship between the people who occupied these sites, this …

Intracellular Survival Of Staphylococcus Aureus In Macrophages During Osteomyelitis, William A. Lathram, Christopher D. Radka

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Staphylococcus aureus, traditionally viewed as an extracellular pathogen, is increasingly recognized for its ability to persist intracellularly, particularly within macrophages. This intracellular lifestyle is central to osteomyelitis, a chronic bone infection characterized by persistent inflammation, bone destruction, and impaired repair. Within bone, S. aureus exploits macrophage plasticity by driving a shift from pro-inflammatory, bactericidal M1-like states to anti-inflammatory, tissue-reparative M2-like phenotypes. This polarization suppresses immune clearance and promotes an environment conducive to bacterial survival and dissemination. Additional strategies – including biofilm formation, small colony variants, and inhibition of phagolysosomal killing – further enhance persistence and immune evasion. While these …

Serglycin Controls Megakaryocyte Retention Of Platelet Factor 4 And Influences Megakaryocyte Fate In Bone Marrow, Joshua Lykins, Isabelle C. Becker, Virginia Camacho, Hammodah Rawhi Hammodah Alfar, Joonwoo Park, Joseph Italiano, Sidney W. Whiteheart

Saha Cardiovascular Research Center Faculty Publications

Megakaryocytes (MKs) produce platelets, and similar to other hematopoietic progenitors, they are involved in homeostatic aspects of their bone marrow niche. MKs release and endocytose various factors, such as platelet factor 4 (PF4)/CXCL4. Here, we show that the intra-α-granular proteoglycan, serglycin (SRGN), plays a key role in this process by retaining PF4, and perhaps other factors, during MK maturation. Immature, SRGN–/– MKs released ~80% of their PF4, and conditioned media from these cells negatively affected wild-type MK differentiation in vitro. This was replicated in wild-type MKs by treatment with the polycation surfen, a known inhibitor of glycosaminoglycan (GAG)/protein interactions. In …

Abcg5/Abcg8-Independent Mechanisms Fail To Maintain Sterol Balance In Mice Fed A High-Cholesterol Diet, Garrett B. Anspach, Rupinder Kaur, Isha Chauhan, Erika L. Savage, Brittney Poole, Victoria P. Noffsinger, Xiaoming Fu, Zeneng Wang, Clairity Voy, Ryan E. Temel, Scott M. Gordon, Robert N. Helsley, Gregory A. Graf

Saha Cardiovascular Research Center Faculty Publications

The ABCG5/ABCG8 (G5G8) sterol transporter opposes the accumulation of dietary xenosterols but is also the primary mediator of biliary cholesterol secretion. In humans and in mouse models of disrupted biliary cholesterol secretion, fecal neutral sterols (FNSs) remain constant, indicating the presence of an alternate pathway for cholesterol excretion. Transintestinal cholesterol elimination or excretion (TICE) is thought to compensate for biliary disruptions and G5G8 insufficiency. We sought to measure the compensatory increase in intestinal cholesterol secretion and provide mechanistic insight for how TICE maintains sterol balance in the absence of hepatic G5G8. Differences were not observed in FNSs between control, acute, …

El Doble Discurso Del Simbolismo De La (Pureza De) Sangre En El Diario Espiritual De La Donada Afroperuana Úrsula De Jesús, Yertty M. Vandermolen

Theses and Dissertations--Hispanic Studies

Purity of Blood Symbolism and Double Discourse in The Spiritual Diary of the Afro-Peruvian Donada Úrsula de Jesús

Through a close reading of The Spiritual Diary, this study examines how the Afro-Peruvian donada Úrsula de Jesús—whose experiences and visions were recorded and transcribed by a group of literate nuns in her convent—employs discursive strategies to dismantle the discourse of blood purity and reformulate the meaning of the blood. Drawing on the Christian belief that all humans are created equally in the image of God and redeemed through the blood of Christ as promised for universal salvation, Úrsula constructs an egalitarian …

Rad Reduction Reveals Therapeutic Potential Of Targeting Cardiomyocyte L-Type Calcium Channel Regulation For Heart Failure, Garrett Elmore

Theses and Dissertations--Physiology

Heart failure (HF) is prevalent and is predicted to increase with the aging population. Dilated cardiomyopathy (DCM) is a common cause of systolic HF. Current therapies fail to address principal issues: compromised systolic function and dysfunctional Ca²⁺ handling. No therapeutic approach exists for direct, positive modulation of cardiomyocyte L-type calcium channels (LTCC). RAD (Ras associated with diabetes) is a key regulator of the cardiac LTCC. RAD is a downstream phosphorylated target of the ß-adrenergic receptor (ß-AR)/cAMP/protein kinase A pathway; phosphorylation augments LTCC activity, contributing to chronotropy, inotropy, and lusitropy. RAD overexpression results in LTCC inhibition, whereas knockout positively modulates …

“It’S An Honor To Be In This Body”: A Black Feminist Grounded Theory Of Embodiment Among Black Womxn Yoga Practitioners (Bwyps), Natalie Malone

Theses and Dissertations--Educational, School, and Counseling Psychology

Black womxn (i.e., individuals whose experiences align with Black girlhood/womanhood or whose bodies are perceived as Black, female, womanly, femme, or a combination) experience significant health and well-being challenges that may hinder their embodiment. Yoga is a complementary therapy that may help Black womxn improve their embodiment. This dissertation qualitatively explores the processes Black womxn yoga practitioners (BWYPs) engage in to cultivate positive embodiment. Participants were N=30 Black womxn who were short- (≤ five years; n=11), medium- (five–10 years; n=10), and long-term (>11 years; n=9) yoga practitioners. Participants completed individual interviews as part of the …

Assessment Of Cerebrospinal Fluid And Blood-Based Biomarkers In Degenerative Cervical Myelopathy: Systematic Review And Meta-Analysis, Harshit Arora, Hassan Darabi, Cassandra C. Wolsh, Kelsey N. Karnik, John C. Gensel, Francis Farhadi

Neurosurgery Faculty Publications

Study Design: Systematic Review and Meta-Analysis.

Objectives: Degenerative cervical myelopathy (DCM), the leading cause of spinal cord injury globally, may clinically manifest with hand numbness and tingling, loss of hand dexterity and impaired balance and gait. Biomarkers have been identified as disease indicators with recent studies exploring the role of structural and inflammatory biomarkers in diagnostic and treatment outcome prediction. The review aims to identify relevant cerebrospinal fluid (CSF) and blood-based biomarkers associated with DCM diagnosis and prognostication.

Methods: The systematic review was conducted as per PRISMA guidelines. A comprehensive search strategy was devised to identify articles evaluating biomarkers in …

Frailty Indices In Patients Undergoing Functional Neurosurgical Procedures: A Systematic Review, Carmelo Venero Jr., Joanna M. Roy, Nirbha Ghurye, Akshay Warrier, Muhammad Usman Khalid, Niels Pacheco-Barrios, Farhan A. Mirza, Christian A. Bowers

Neurosurgery Faculty Publications

Introduction: Functional neurosurgery covers a wide array of neurological disorders with an equally vast array of treatment modalities, including neuromodulation, decompressive, and ablative therapies for disparate pathologies such as pain, neuromodulation, disconnection, and refractory epilepsy. One of the most common functional treatments is deep brain stimulation for movement disorders and select psychiatric diseases. Functional neurosurgery treats patients with reduced quality of life from pathological neuronal pathways. Optimal patient selection by preoperatively identifying high-risk patients is critical for avoiding as many operative complications as possible, in addition to managing complications better once they occur. Frailty indices have demonstrated superior discrimination in …

A High-Resolution Record Of Late Holocene Drought In The Eastern Sierra Nevada (California, Usa) From June Lake Carbonate Geochemistry, Eva C. Lyon, Andrea M. Erhardt, Laura C. Streib, Susan R.H. Zimmerman, Michael M. Mcglue

Earth and Environmental Sciences Faculty Publications

As historic drought conditions become more common in western North America, Late Quaternary hydroclimate records become vital for putting present anthropogenic conditions into a longer-term context. Here, we establish a high-resolution record of drought for the eastern Sierra Nevada (California) using lacustrine carbonates from well-dated sediment cores. We used oxygen and carbon stable-isotope ratios, combined with high-resolution scanning X-ray fluorescence counts of calcium (Ca) and titanium (Ti), to reconstruct the drought record over the last 4600 years in June Lake. We found elevated δ¹⁸O and δ¹³C carbonate isotope values coinciding with peaks in both total inorganic …

A Multi-Objective Optimization Model For Cropland Design Considering Profit, Biodiversity, And Ecosystem Services, Caleb H. Geissler, Nathan L. Haan, Bruno Basso, Ames Fowler, Douglas A. Landis, Tyler J. Lark, Christos T. Maravelias

Entomology Faculty Publications

More sustainable agricultural methods are needed to alleviate the decreases in biodiversity and ecosystem services that have occurred because of industrial agriculture. One such method is the inclusion of alternative crops into croplands that can support biodiversity, reduce erosion and chemical runoff, and sequester carbon in the soil. However, the question of where such crops should be planted to balance competing economic and environmental objectives remains open. To this end, we develop a mixed-integer quadratically constrained program to optimize the layout of a cropland considering economic, biodiversity, greenhouse gas emissions, and water quality objectives. We include spatially varying fertilization as …

Molecular Mechanisms And Comparative Transcriptomics Of Diapause In Two Corn Rootworm Species (Diabrotica Spp.), Melise C. Lecheta, Chad Nielson, B. Wade French, Emily Nadeau, Nicholas M. Teets

Entomology Faculty Publications

Diapause is a programmed developmental arrest that can occur at any developmental stage depending on species, but the mechanisms that underscore embryonic diapause are poorly understood. Here, we identified molecular mechanisms underscoring distinct phases of diapause in the Diabrotica spp. complex. This species complex in- cludes economically significant agricultural pests, notably the western corn rootworm (WCR) and northern corn rootworm (NCR), which cause major losses in maize production. Rootworms undergo an obligate embryonic diapause to synchronize their life cycles with host plants, and we sequenced transcriptomes from both species at five time points (pre-diapause, diapause initiation, diapause maintenance, diapause termination, …

An Evaluation Of Kentucky’S Policy Landscape And Its Impacts On High-Growth Firms In The Commonwealth, Ivanna Patrick, Jordan Arnold, Devin Dunigan

MPA/MPP/MPFM Capstone Projects

There is significant research on high-growth firms (HGFs), though there is little research focusing on such businesses in Kentucky. By comparing Kentucky to two similar states that are economic competitors and in the context of the Kentucky Innovation Act of 2000, we find that Kentucky has a relatively fewer number of HGFs, even compared to itself at the time of the bill’s passage. Ultimately, we determined that there was a focus on high-tech firms in Kentucky that may be detrimental to the growth and success of HGFs in other industries; furthermore, it would serve the state to focus enhanced efforts …

Addressing Municipal Road Aid Funding In Kentucky During The Era Of Electric Vehicles, Jacob Bruce, Tyler Chapman, Blake Girdler

MPA/MPP/MPFM Capstone Projects

The rapid rise of electric vehicles (EVs) poses a growing threat to Kentucky’s Municipal Road Aid Fund, which relies heavily on fuel tax revenues. As EV adoption increases and fuel consumption declines, the existing funding model becomes increasingly unsustainable, jeopardizing road maintenance, infrastructure development, and municipal services across the state. Commissioned by the Kentucky League of Cities, this study investigates viable policy solutions to ensure long-term fiscal stability for municipal road funding in an electrifying transportation landscape. Drawing from comparative analyses of peer and neighboring states, the report evaluates alternative funding mechanisms such as road usage charges, EV-specific registration fees, …

Strategic Alignment Of Lexington Public Library And Art Community, Jonnisa Ferguson, Samantha Metzger-Elder

MPA/MPP/MPFM Capstone Projects

Amidst the evolving economic, political, religious, social, and technological landscape of the United States, one enduring element across communities has been the presence and importance of public libraries. Despite the decreasing number of genuinely public spaces in America, public libraries remain accessible and welcoming to all (Howard, 2019). Modern public libraries unite people and are "rewriting common assumptions of what people think a library does" (Carlson, 2024). Going far beyond books, libraries are serving as a "trusted public common for social innovation and civic engagement," partnering with community organizations to address daily living issues (i.e., food insecurities and professional development), …

Lfucg: Assessing Homeownership Initiatives Through Document Analysis, Matthew D. Hallock, Dakota Hensley, Jordan G. Salem

MPA/MPP/MPFM Capstone Projects

The Lexington, Kentucky Vice Mayor’s Office is exploring ways to expand access to homeownership as a means to facilitate wealth creation for its citizens. This paper outlines literature highlighting the issues surrounding the shortage of housing and past discriminatory policies which negatively affected Lexington. Specific criteria were used to identify cities that resemble Lexington to see what housing programs those cities have implemented and to see what can be reasonably applied to Lexington. Descriptions and themes of the identified programs are provided to provide the Lexington Vice Mayor’s Office with policy options to increase avenues to first-time homeownership.

Ensuring A Future For The Past: Balancing Heritage Tourism And Historic Preservation, Kyra Frew Sexauer

MPA/MPP/MPFM Capstone Projects

Savannah’s historic city plan, Charleston’s colonial architecture, and New Orleans’ Creole and Cajun culture and cuisine all have a commonality: they tangibly and intangibly connect the past to the present. Each city has a distinct and recognizable landscape, shaped by its built environment, history, and culture, which is listed as a National Historic Landmark District (NHLD) – the most prestigious recognition a historic district can receive in the United States. Heritage tourists are drawn to these places by their history, culture, and authenticity. In 2022, a combined 42,320,000 million tourists poured into the streets of Savannah, Charleston, and New Orleans. …

A Comparative Study Of State-Level Fast Programs To Identify Best Practices For Kentucky, Alana Morgan

MPA/MPP/MPFM Capstone Projects

This capstone project examines best practices among state-level innovation programs participating in the U.S. Small Business Administration’s Federal and State Technology (FAST) Partnership Program, with a specific focus on the Kentucky Science and Engineering Foundation (KSEF). As a key player in Kentucky’s innovation ecosystem, KSEF supports small businesses and entrepreneurs in pursuing federal Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) funding. This study evaluates KSEF’s current program effectiveness and identifies strategies from similar states that could strengthen Kentucky’s outcomes in securing federal innovation funding.

Using a qualitative comparative research design, this study analyzes interviews with program …

The Impact Of Medicaid Postpartum Coverage Expansion On Insurance Coverage In California, Akuoma Nwannunu

MPA/MPP/MPFM Capstone Projects

This study examines the impact of California’s 12-month Medicaid postpartum expansion on insurance coverage outcomes among recent mothers using pooled data from the American Community Survey (ACS) microdata from 2018-2019 and 2022-2023. A quasi-experimental difference-in-differences design compared postpartum mothers with non-postpartum mothers to assess whether the policy altered Medicaid enrollment, private coverage, or uninsurance in the first two years after implementation. Findings show that Medicaid coverage increased slightly and uninsurance declined modestly among postpartum mothers, while private coverage remained stable. Across all three outcomes, however, the DID estimates were small and statistically insignificant, which indicates early but limited measurable effects. …