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Articles 751 - 780 of 27412
Full-Text Articles in Entire DC Network
Measurement Of Kaon Directed Flow In Au+Au Collisions In The High Baryon Density Region, B. E. Aboona, J. Adam, G. Agakishiev, I. Aggarwal, M. M. Aggarwal, Z. Ahammed, A. Aitbayev, I. Alekseev, E. Alpatov, A. K. Alshammri, A. Aparin, S. Aslam, J. Atchison, G. S. Averichev, V. Bairathi, X. Bao, P. Barik, K. Barish, S. Behera, P. Bhagat, A. Bhasin, S. Bhatta, I. G. Bordyuzhin, J. D. Brandenburg, A. V. Brandin, C. Broodo, X. Z. Cai, H. Caines, M. Calderón De La Barca Sánchez, D. Cebra, J. Ceska
Measurement Of Kaon Directed Flow In Au+Au Collisions In The High Baryon Density Region, B. E. Aboona, J. Adam, G. Agakishiev, I. Aggarwal, M. M. Aggarwal, Z. Ahammed, A. Aitbayev, I. Alekseev, E. Alpatov, A. K. Alshammri, A. Aparin, S. Aslam, J. Atchison, G. S. Averichev, V. Bairathi, X. Bao, P. Barik, K. Barish, S. Behera, P. Bhagat, A. Bhasin, S. Bhatta, I. G. Bordyuzhin, J. D. Brandenburg, A. V. Brandin, C. Broodo, X. Z. Cai, H. Caines, M. Calderón De La Barca Sánchez, D. Cebra, J. Ceska
Physics and Astronomy Faculty Publications
Rapidity-odd directed flow v 1 measurements are presented for K ± and KS0 in Au + Au collisions for sNN from 3.0 to 3.9 GeV with the STAR experiment. For comparison, v 1 of π ± , protons, and Λ from the same collisions are also discussed. The mid-rapidity v 1 slope dv1/dy|y=0 for protons and Λ is positive in these collisions. On the other hand, v 1 slope of kaons exhibits a strong pT dependence: negative at pT< 0.6 GeV/ c and positive at higher pT. A similar pT dependence is also evident for the v …
Simulation And Optimization Of The Active Magnetic Shield Of The N2edm Experiment, N. J. Ayres, G. Ban, G. Bison, K. Bodek, V. Bondar, T. Bouillaud, G. L. Caratsch, E. Chanel, W. Chen, C. Crawford, V. Czamler, C. B. Doorenbos, S. Emmeneger, S. K. Ermakov, M. Ferry, M. Fertl, A. Fratangelo, D. Galbinski, W. C. Griffith, Z. D. Grujic, K. Kirch, V. Kletzl, J. Krempel, B. Lauss, T. Lefort, A. Lejuez, K. Michielsen, J. Micko, P. Mullan, O. Naviliat-Cuncic, F. M. Piegsa
Simulation And Optimization Of The Active Magnetic Shield Of The N2edm Experiment, N. J. Ayres, G. Ban, G. Bison, K. Bodek, V. Bondar, T. Bouillaud, G. L. Caratsch, E. Chanel, W. Chen, C. Crawford, V. Czamler, C. B. Doorenbos, S. Emmeneger, S. K. Ermakov, M. Ferry, M. Fertl, A. Fratangelo, D. Galbinski, W. C. Griffith, Z. D. Grujic, K. Kirch, V. Kletzl, J. Krempel, B. Lauss, T. Lefort, A. Lejuez, K. Michielsen, J. Micko, P. Mullan, O. Naviliat-Cuncic, F. M. Piegsa
Physics and Astronomy Faculty Publications
The n2EDM experiment at the Paul Scherrer Institute aims to conduct a high-sensitivity search for the electric dipole moment of the neutron. Magnetic stability and control are achieved through a combination of passive shielding, provided by a magnetically shielded room (MSR), and a surrounding active field compensation system by an Active Magnetic Shield (AMS). The AMS is a feedback-controlled system of eight coils spanned on an irregular grid, designed to provide magnetic stability to the enclosed volume by actively suppressing external magnetic disturbances. It can compensate static and variable magnetic fields up to ± 50 μT (homogeneous components) and ± …
Muscle Atrophy After Acl Reconstruction Involves Molecular Mechanisms Beyond Unloading, Alexander R. Keeble, Gonzalez Velez Sara, Nicholas T. Thomas, Allison M. Owen, Austin V. Stone, Darren L. Johnson, Julián Candia, Luigi Ferrucci, Marco Narici, Esther E. Dupont-Versteegden, Brian Noehren, Martino V. Franchi, Christopher S. Fry
Muscle Atrophy After Acl Reconstruction Involves Molecular Mechanisms Beyond Unloading, Alexander R. Keeble, Gonzalez Velez Sara, Nicholas T. Thomas, Allison M. Owen, Austin V. Stone, Darren L. Johnson, Julián Candia, Luigi Ferrucci, Marco Narici, Esther E. Dupont-Versteegden, Brian Noehren, Martino V. Franchi, Christopher S. Fry
Physiology Faculty Publications
Anterior cruciate ligament reconstruction (ACLR) leads to profound muscle atrophy and weakness that remain resistant to rehabilitation. Although early recovery typically involves a brief period of limb unloading, the degree to which disuse alone accounts for muscle pathology after ACLR remains unclear. Here, we leveraged publicly available RNA-seq datasets of muscle biopsies from vastus lateralis obtained 7 days after ACLR or 10 days after unilateral lower limb suspension (ULLS), each with matched control limbs, to directly compare disuse-driven and ACLR-specific early transcriptional responses. Despite similar periods of reduced loading, substantial transcriptomic divergence was identified using both intersection and interaction bioinformatic …
Protective Row Covers For Management Of Flea Beetles In Organic Eggplant Production In The Southeastern Us, Elaine Losekamp, Robert Brockman, Viktor Halmos, Kathleen Fiske Pulliam, Ryan Kuesel, Ric Bessin, Delia Scott, Mark Williams, David Gonthier
Protective Row Covers For Management Of Flea Beetles In Organic Eggplant Production In The Southeastern Us, Elaine Losekamp, Robert Brockman, Viktor Halmos, Kathleen Fiske Pulliam, Ryan Kuesel, Ric Bessin, Delia Scott, Mark Williams, David Gonthier
Entomology Faculty Publications
Organic eggplant production in the United States is challenged by flea beetles, which stunt eggplant growth and reduce yield. Across four experiments between 2019 and 2024, we compared the effects of various pest management strategies on flea beetle abundance, damage, and marketable yield in eggplant production, focusing on row covers and organic insecticides in later years of the study. Treatments included fine-mesh row covers, organic insecticides, and untreated controls (all years); reflective plastic mulch (2019); various essential oils (2019–2020); conventional insecticide control (2019–2020); and spunbonded row covers (2019–2021). Low flea beetle pressure was observed in 2019 and 2020; consequently, experiments …
The Association Between Apoe Ε4 Carrierships And The Detection Of Amyloid Positivity Using An Alzheimer's Disease Proteomic Blood Test In Asymptomatic Down Syndrome, Lubnaa Badriyyah Abdullah, Fan Zhang, Melissa Petersen, James Hall, Benjamin L. Handen, Mark Mapstone, Brad Christian, Elizabeth Head, Sigan Harley, Howard Andrews, Joseph H. Lee, Dana Tudorascu, Christy Hom, Shahid Zaman, Adam M. Brickman, Diana Rosas, Annie Cohen, Jordan P. Harp, Frederick Schmitt, Lauren Ptomey, Jeffrey M. Burns, Ira T. Lott, Florence Lai, Charles Laymon, Carlos Cruchaga, Sid O'Bryant, Beau M. Ances
The Association Between Apoe Ε4 Carrierships And The Detection Of Amyloid Positivity Using An Alzheimer's Disease Proteomic Blood Test In Asymptomatic Down Syndrome, Lubnaa Badriyyah Abdullah, Fan Zhang, Melissa Petersen, James Hall, Benjamin L. Handen, Mark Mapstone, Brad Christian, Elizabeth Head, Sigan Harley, Howard Andrews, Joseph H. Lee, Dana Tudorascu, Christy Hom, Shahid Zaman, Adam M. Brickman, Diana Rosas, Annie Cohen, Jordan P. Harp, Frederick Schmitt, Lauren Ptomey, Jeffrey M. Burns, Ira T. Lott, Florence Lai, Charles Laymon, Carlos Cruchaga, Sid O'Bryant, Beau M. Ances
Neurology Faculty Publications
INTRODUCTION: This study evaluates plasma-based proteomic profiles for predicting amyloid positivity in adults with Down syndrome (DS) and examines the impact of apolipoprotein E ε4 (APOE ε4) on test performance. METHODS: Cross-sectional data from 290 adults with DS were analyzed using single molecule array (SIMOA) technology to measure plasma amyloid beta (Aβ)42, Aβ40, neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), tau phosphorylated at threonine 181, and total tau. Amyloid burden was quantified using Pittsburgh Compound B and (18)F-florbetapir Aβ positron emission tomography. Support vector machine analyses were conducted with biomarkers as predictors and age, sex, and APOE ε4 …
Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, Hunter N.B. Moseley
Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, Hunter N.B. Moseley
Markey Cancer Center Faculty Publications
Background: Almost all correlation measures currently available are unable to directly handle missing values. Typically, missing values are either ignored completely by removing them or are imputed and used in the calculation of the correlation coefficient. In either case, the correlation value will be impacted based on the perspective that the missing data represents no useful information. However, missing values occur in real datasets for a variety of reasons. In metabolomics datasets a major reason for missing values is that a specific measurable phenomenon falls below the detection limits of the analytical instrumentation (left-censored values). These missing data are not …
Role Of Succinate Dehydrogenase In Age-Related Th17 Inflammation, Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica-Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath
Role Of Succinate Dehydrogenase In Age-Related Th17 Inflammation, Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica-Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath
Markey Cancer Center Faculty Publications
Age-related cellular changes negatively impact CD4+ T cell function. Our prior work showed that mitochondrial complex II (succinate dehydrogenase [SDH]) expression was upregulated in T cells from older (O) adults (60–80 years old). T cells from older adults also produced higher amounts of cytokines generally considered proinflammatory, such as Th17 cytokines IL-17A/F and IL-21, and the Th-17-supportive cytokine IL-6, compared to T cells from younger (Y) adults (25–40 years old). The objective of our study is to evaluate whether hyperactivation of SDH is required for the induction of proinflammatory cytokines and the mechanistic link between SDH and Th17 cytokine …
Systemic Consequences Of Chronic Ethanol Intake, Muni Swamy Ganjayi, Thomas A. Krauss, Gage E. Demster, Sehyung Park, Garrett B. Anspach, Sarah R. Anthony, Shaohua Wang, Michael Tranter, Robert N. Helsley, Cory W. Baumann
Systemic Consequences Of Chronic Ethanol Intake, Muni Swamy Ganjayi, Thomas A. Krauss, Gage E. Demster, Sehyung Park, Garrett B. Anspach, Sarah R. Anthony, Shaohua Wang, Michael Tranter, Robert N. Helsley, Cory W. Baumann
Markey Cancer Center Faculty Publications
Chronic ethanol (EtOH) consumption is a major contributor to multi-organ dysfunction, yet its systemic effects remain incompletely understood. To address this, we utilized a physiologically relevant long-term mouse model, administering 20% EtOH in drinking water for 60 weeks, to investigate the integrated consequences of chronic exposure. EtOH-consuming mice (0.4–0.5 mL/day) exhibited > 30% reductions in chow and fluid intake, resulting in a 12% decrease in total caloric intake compared to controls (p < 0.001). Body mass remained similar until Week 52, after which EtOH-treated mice had lower body mass due to reductions in both lean and fat mass (p ≤ 0.004). Functional assessments revealed impaired treadmill endurance (−17%) and grip strength (−11%) (p ≤ 0.037), while motor coordination remained unaffected (p = 0.203). Chronic EtOH exposure significantly altered gut microbiota composition, reducing Lactobacillus and enriching Faecalibaculum, Clostridium, and Bifidobacterium at the genus level. These changes were accompanied by marked depletion of short-chain fatty acids (p ≤ 0.05). Indirect markers of gut permeability (serum LPS & zonulin) and liver injury (serum ALT & AST, hepatic amyloid content) were elevated, alongside increased total cholesterol and > 62% upregulation of hepatic TNFα, IL-6 & serum amyloid A (p ≤ 0.046). EtOH also induced dyslipidemia and glucose intolerance (p ≤ 0.041), although transcriptomic changes in white adipose …
Treating Maternal Mental Health Problems With An App-Based Program, Leslie E. Roos, Anna L. Mackinnon, E. Bailin Xie, Kaeley M. Simpson, Charlie Rioux, Kristin A. Reynolds, Ryan J. Giuliano, Jennifer Harrington, Jennifer L.P. Protudjer, Shannon Sauer-Zavala, Gerald F. Giesbrecht, Catherine Lebel, Dana Watts, Madeline Belows, Lara Penner-Goeke, Makayla Freeman, Lianne Tomfohr-Madsen
Treating Maternal Mental Health Problems With An App-Based Program, Leslie E. Roos, Anna L. Mackinnon, E. Bailin Xie, Kaeley M. Simpson, Charlie Rioux, Kristin A. Reynolds, Ryan J. Giuliano, Jennifer Harrington, Jennifer L.P. Protudjer, Shannon Sauer-Zavala, Gerald F. Giesbrecht, Catherine Lebel, Dana Watts, Madeline Belows, Lara Penner-Goeke, Makayla Freeman, Lianne Tomfohr-Madsen
Psychology Faculty Publications
OBJECTIVES: Exposure to maternal mental illness in the first 3 years of life is associated with poor child outcomes. Many mothers experience mental health problems and few have access to evidence-based treatments. Mobile health treatments show promise for mood and anxiety disorders but rarely include parenting strategies. This study evaluated the efficacy of Building Emotional Awareness and Mental Health (BEAM), a 10-week app-based therapist-guided program, which responds to maternal mental health and parenting needs. METHOD: A two-arm, Phase III randomized controlled trial was conducted to evaluate the BEAM intervention compared to unrestricted services-as-usual. Participants completed self-report measures at eligibility, prior …
Oral Health In People With Schizophrenia, Leire Urien, Ainara Arnaiz, Xabier Marichalar-Mendia, Unax Lertxundi, Jose De Leon, Agate Txurruka, Nerea Jauregizar, Teresa Morera-Herreras
Oral Health In People With Schizophrenia, Leire Urien, Ainara Arnaiz, Xabier Marichalar-Mendia, Unax Lertxundi, Jose De Leon, Agate Txurruka, Nerea Jauregizar, Teresa Morera-Herreras
Psychiatry Faculty Publications
Aim This study aimed to assess the oral health status of individuals with schizophrenia and explore its association with behavioural and pharmacological factors, with particular focus on long-term antipsychotic treatment and cumulative anticholinergic burden. Methods A total of 153 adults with schizophrenia (18–65 years) from the Mental Health Network of Bizkaia (Spain), all under antipsychotic treatment for ≥12 months, were evaluated and compared with 153 controls from the general population. Data on socio-demographic variables, tobacco use and oral hygiene habits were collected. Oral health was assessed using the Decayed, Missing and Filled Teeth (DMFT) index and the Community Periodontal Index …
Generative Models And Synthetic Data In Clinical Prediction Models, Anthony A. Mangino, Taha Ahmed, Vincent L. Sorrell
Generative Models And Synthetic Data In Clinical Prediction Models, Anthony A. Mangino, Taha Ahmed, Vincent L. Sorrell
Radiology Faculty Publications
Introduction: Reproducibility, consistency, and transparency are essential to responsible and ethical scientific inquiry, though practices supporting these qualities are often neglected. However, in many cases data are confidential or otherwise unable to be shared publicly. This tutorial describes a method utilizing generative adversarial networks (GANs) to create synthetic data that are sufficiently similar to the original dataset in such cases where the source data cannot be shared or where the source data are too sparse as to internally validate results. Methods: Utilizing an exemplar study that aimed to create a clinical prediction model employing a novel echocardiographic measurement to differentiate …
Congress's Mistaken Ip Power And Our Hybrid Constitutionalism, Barry P. Mcdonald
Congress's Mistaken Ip Power And Our Hybrid Constitutionalism, Barry P. Mcdonald
Kentucky Law Journal
No abstract provided.
A Tale Of Two Landlords, Christopher J. Ryan Jr.
A Tale Of Two Landlords, Christopher J. Ryan Jr.
Kentucky Law Journal
No abstract provided.
Domestic Guestworkers: A Call To End The H-2b Program And Empower American Workers, Preston Huennekens
Domestic Guestworkers: A Call To End The H-2b Program And Empower American Workers, Preston Huennekens
Kentucky Law Journal
No abstract provided.
Federal Prosecution In The Shadows Of Constitutional Immunity, J. Richard Broughton
Federal Prosecution In The Shadows Of Constitutional Immunity, J. Richard Broughton
Kentucky Law Journal
No abstract provided.
Somebody's Watching Me: Modern Abusers Use Modern Methods Of Control, Savannah Molyneaux
Somebody's Watching Me: Modern Abusers Use Modern Methods Of Control, Savannah Molyneaux
Kentucky Law Journal
No abstract provided.
Happy Belated Iep: How A Notice Of Procedural Safeguards Fails Children With Specific Learning Disabilities, Chrystal Clodomir
Happy Belated Iep: How A Notice Of Procedural Safeguards Fails Children With Specific Learning Disabilities, Chrystal Clodomir
Kentucky Law Journal
No abstract provided.
Campus Coverage: How Biden's Title Ix Regulations Threaten Free Speech, Academic Freedom, And University Liability, Alex Drury
Kentucky Law Journal
No abstract provided.
Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss
Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss
Progress in Scale Modeling, an International Journal
The phenomenon of Taylor or shear-induced dispersion of a non-passive scalar field in a pulsatile pipe flow is investigated, accounting for the scalar field's influence on fluid density and transport coefficients. By employing multiple scale analysis, an effective one-dimensional, unsteady mixing problem for the scalar field is obtained, which includes the diffusion coefficient for shear-induced dispersion. The resulting governing equations are applicable to a range of scalar transport problems in pulsatile pipe flows.
Methane Emissions From Underground Coal Mines, Marcelo Guzman, Thomas Parris, Stephen Greb, Cortland F. Eble, Sean Bailey
Methane Emissions From Underground Coal Mines, Marcelo Guzman, Thomas Parris, Stephen Greb, Cortland F. Eble, Sean Bailey
Mechanical Engineering Faculty Publications
Methane emissions from Kentucky underground coal mines were measured using near-infrared spectrometers deployed on a vehicle, an airplane, and a small uncrewed aerial system (sUAS), offering insights into the effectiveness of these methods under real-world conditions. From 2021–2022, surveys covered 14 active, 4 inactive, and 4 abandoned mines across Kentucky’s coal-producing basins. Vehicle-based surveys at 13 active mines detected methane anomalies at 9 sites with anomaly lengths spanning tens to hundreds of meters and peak emissions of 665 ± 229 kg h–1 from two Cardinal mine fans. Airborne GHGSat surveys identified anomalies at 3 sites, including a peak of 1062 …
Synthesis And Structures Of Ru(Ii)-P-Cymene Sandwich Complexes With Electron-Withdrawing Cyclopentadienyl Ligands, Uttam R. Pokharel, Sean Parkin, John P. Selegue
Synthesis And Structures Of Ru(Ii)-P-Cymene Sandwich Complexes With Electron-Withdrawing Cyclopentadienyl Ligands, Uttam R. Pokharel, Sean Parkin, John P. Selegue
Chemistry Faculty Publications
A modular synthetic route has been developed to prepare a new series of cationic ruthenium(II) complexes with electron-withdrawing 1,2-diacylcyclopentadienyl ligands. The 2-acyl-6-hydroxyfulvenes were synthesized from cyclopentadienide and acyl chlorides and converted to Tl(I) cyclopentadienyl salts using Tl2SO4/KOH. Transmetalation with [Ru(η6-p-cymene)(μ-Cl)Cl]2 followed by PF6− metathesis gives the complexes [Ru{η5-1,2-C5H3(CO–R)2}(η6-p-cymene)][PF6] (R = t-Bu, p-Tol, p-ClC6H4, p-IC6H4) in moderate to high yields. The new compounds were characterized by NMR and IR spectroscopy; mass spectrometry …
Molecular Gas And Star Formation In Central Rings Across Nearby Galaxies, Damian R. Gleis, Sophia K. Stuber, Eva Schinnerer, Justus Neumann, Sharon E. Meidt, Miguel Querejeta, Eric Emsellem, Adam K. Leroy, Ashley T. Barnes, Frank Bigiel, Charlie Burton, Mélanie Chevance, Daniel A. Dale, Kathryn Grasha, Ralf S. Klessen, Rebecca C. Levy, Lukas Neumann, Hsi An Pan, Marina Ruiz-García, Mattia C. Sormani, Jiayi Sun, Yu Hsuan Teng, Thomas G. Williams
Molecular Gas And Star Formation In Central Rings Across Nearby Galaxies, Damian R. Gleis, Sophia K. Stuber, Eva Schinnerer, Justus Neumann, Sharon E. Meidt, Miguel Querejeta, Eric Emsellem, Adam K. Leroy, Ashley T. Barnes, Frank Bigiel, Charlie Burton, Mélanie Chevance, Daniel A. Dale, Kathryn Grasha, Ralf S. Klessen, Rebecca C. Levy, Lukas Neumann, Hsi An Pan, Marina Ruiz-García, Mattia C. Sormani, Jiayi Sun, Yu Hsuan Teng, Thomas G. Williams
Physics and Astronomy Faculty Publications
Context. Nearby galaxies exhibit a variety of structures, including so-called central or (circum-)nuclear rings that are similar to the Milky Way (MW) Central Molecular Zone (CMZ). These rings are common in barred galaxies and can be gas-rich and highly star-forming. Aims. We aim to study the molecular gas content and star formation rate of central rings within nearby galaxies and link them to global galaxy properties, especially the bar morphology. Methods. We utilized 1″(≲100 pc) resolution CO(2–1) observations from the PHANGS-ALMA survey, visually identifying 20 central rings and determine their properties. For 14 of these rings, MUSE observations tracing star …
Scratch-Induced Damage Of Doped Dlc And Mos2 Coatings—Deep Symbolic Analysis, Ming Liu, Zhitong Xu, Noraphat Yuktanan, Tang Gu, Guangan Zhang, Jinyang Jiang, Fuqian Yang, Rui Liang
Scratch-Induced Damage Of Doped Dlc And Mos2 Coatings—Deep Symbolic Analysis, Ming Liu, Zhitong Xu, Noraphat Yuktanan, Tang Gu, Guangan Zhang, Jinyang Jiang, Fuqian Yang, Rui Liang
Chemical and Materials Engineering Faculty Publications
Understanding contact-induced damage is of paramount importance in the analysis of the lifespan and performance of surface coatings. In this work, we investigate the effects of dopants and interlayers on the structural durability of diamond-like carbon coatings (DLCs) and molybdenum disulfide (MoS2) coatings on stainless steel via microscratch tests. The analysis of X-ray photoelectron spectroscopy (XPS) survey spectra and Raman spectra of the DLCs shows that the ratio of sp2/sp3 (i.e., the intensity ratio of sp2 to sp3 obtained via XPS) is proportional to ID/IG, where ID and …
Pan-Genome Analysis Of The Fructokinase Gene Family Reveals A Light-Regulated Siphyc–Sifrk4 Module Controlling Carbon Partitioning In Foxtail Millet, Lu He, Juan Zhao, Guangxin Wang, Ling Yuan, Xingchun Wang, Zhirong Yang
Pan-Genome Analysis Of The Fructokinase Gene Family Reveals A Light-Regulated Siphyc–Sifrk4 Module Controlling Carbon Partitioning In Foxtail Millet, Lu He, Juan Zhao, Guangxin Wang, Ling Yuan, Xingchun Wang, Zhirong Yang
Plant and Soil Sciences Faculty Publications
Fructokinase (FRK) initiates fructose phosphorylation, channeling carbon into central metabolic pathways, yet its functional diversity and regulatory networks in C4 cereals remain poorly understood. Here, we performed a comprehensive pan-genome analysis of the FRK gene family in foxtail millet (Setaria italica), identifying 697 SiFRKs across 110 accessions and revealing extensive presence–absence variation shaped by evolution and domestication. Among nine characterized members in the reference genome, SiFRK4 exhibited broad and high expression, a diurnal rhythm, and substantial natural variation. Biochemical assays confirmed its fructokinase activity in vitro. We discovered a novel physical interaction between SiFRK4 and the key photoreceptor Phytochrome …
Stress-Induced Bandgap Modulation In Semiconductor Quantum Wells, Saurabh Singh, Fuqian Yang
Stress-Induced Bandgap Modulation In Semiconductor Quantum Wells, Saurabh Singh, Fuqian Yang
Chemical and Materials Engineering Faculty Publications
Strained semiconductor quantum wells have been an active area of research for more than three decades. However, a major part of the reported literature has shown a core focus on the theoretical and experimental investigations of their energy band structures under different internal and external perturbations, taking strain parameters as the basis and studying their resulting effects on various optoelectrical properties of the strained quantum wells. However, since stress parameters can be measured more easily and with an enhanced level of accuracy compared to strain parameters, developing a stress-based analytical framework offers distinct advantages. This study focuses on the theoretical …
Mauve, Luca Cortese, Adam Brian Watts, Jiayi Sun, Sriram Sankar, Barbara Catinella, Toby Brown, Alessandro Boselli, Pavel Jáchym, Tutku Kolcu, Sabine Thater, Jesse Van De Sande, Vicente Villanueva
Mauve, Luca Cortese, Adam Brian Watts, Jiayi Sun, Sriram Sankar, Barbara Catinella, Toby Brown, Alessandro Boselli, Pavel Jáchym, Tutku Kolcu, Sabine Thater, Jesse Van De Sande, Vicente Villanueva
Physics and Astronomy Faculty Publications
We present a multiphase study of the star-formation-driven outflow in the Virgo galaxy NGC 4383, combining ALMA CO(2-1) data with deep MeerKAT Hi imaging and MUSE spectroscopy obtained as part of the Multiphase Astrophysics to Unveil the Virgo Environment (MAUVE) program. Our previous work revealed a spectacular ionised outflow, but the effect of the outflow on the cold phase remained unclear. Our analysis shows that potentially outflowing molecular gas is detected only within the inner 1 kpc above the disc, where CO clouds exhibit disturbed kinematics and spatial correspondence with the ionisation cone. At larger heights, the CO surface brightness …
Spatial Control Of Myosin Regulatory Light Chain Phosphorylation Modulates Cardiac Thick Filament Mechanosensing, Caterina Squarci, Daniel Koch, Paul Anaya, Kenneth S. Campbell, Thomas Kampourakis
Spatial Control Of Myosin Regulatory Light Chain Phosphorylation Modulates Cardiac Thick Filament Mechanosensing, Caterina Squarci, Daniel Koch, Paul Anaya, Kenneth S. Campbell, Thomas Kampourakis
Physiology Faculty Publications
The heart can adapt its performance in response to changing metabolic demands of the rest of the body. A central mechanism intrinsic to the heart is to modulate the function of the cardiac contractile proteins via posttranslational modifications. Although phosphorylation of the cardiac myosin motor-associated regulatory light chain (RLC) by cardiac myosin light chain kinase (cMLCK) has been recognized as a key signaling pathway to increase myocardial contractile function, little is known about its molecular mechanism of action. Here, we show that phosphorylation of RLC is not a stochastic process but a spatially tightly controlled mechanism in the cardiac sarcomere. …
Duration And Properties Of The Embedded Phase Of Star Formation In 37 Nearby Galaxies From Phangs-Jwst, Lise Ramambason, Mélanie Chevance, Jaeyeon Kim, Francesco Belfiore, J. M. Diederik Kruijssen, Andrea Romanelli, Amirnezam Amiri, Médéric Boquien, Ryan Chown, Daniel A. Dale, Simthembile Dlamini, Oleg V. Egorov, Ivan Gerasimov, Simon C.O. Glover, Kathryn Grasha, Hamid Hassani, Hwihyun Kim, Kathryn Kreckel, Hannah Koziol, Adam K. Leroy, José Eduardo Méndez-Delgado, Justus Neumann, Lukas Neumann, Hsi An Pan, Debosmita Pathak, Karin Sandstrom, Sumit K. Sarbadhicary, Eva Schinnerer, Jiayi Sun, Jessica Sutter, David A. Thilker, Leonardo Ubeda
Duration And Properties Of The Embedded Phase Of Star Formation In 37 Nearby Galaxies From Phangs-Jwst, Lise Ramambason, Mélanie Chevance, Jaeyeon Kim, Francesco Belfiore, J. M. Diederik Kruijssen, Andrea Romanelli, Amirnezam Amiri, Médéric Boquien, Ryan Chown, Daniel A. Dale, Simthembile Dlamini, Oleg V. Egorov, Ivan Gerasimov, Simon C.O. Glover, Kathryn Grasha, Hamid Hassani, Hwihyun Kim, Kathryn Kreckel, Hannah Koziol, Adam K. Leroy, José Eduardo Méndez-Delgado, Justus Neumann, Lukas Neumann, Hsi An Pan, Debosmita Pathak, Karin Sandstrom, Sumit K. Sarbadhicary, Eva Schinnerer, Jiayi Sun, Jessica Sutter, David A. Thilker, Leonardo Ubeda
Physics and Astronomy Faculty Publications
Light reprocessed by dust grains emitting in the infrared enables the study of the physics at play in dusty embedded regions, where ultraviolet and optical wavelengths are attenuated. Infrared telescopes such as JWST have made it possible to study the earliest feedback phases, when stars are shielded by cocoons of gas and dust. Comprehending this phase is crucial for unravelling the effects of feedback from young stars that leads to their emergence and the dispersal of their host molecular clouds. Here we show that the transition from the embedded to the exposed phase of star formation is short (< 4 Myr) and sometimes almost absent (< 1 Myr) across a sample of 37 nearby star-forming galaxies covering a wide range of morphologies, from massive barred spirals to irregular dwarfs. The short duration of the dust-clearing timescales suggests a predominant role of pre-supernova feedback mechanisms in revealing newborn stars, confirming previous results on smaller samples and allowing, for the first time, a statistical analysis of their dependencies. We find that the timescales associated with mid-infrared emission at 21 μm, tracing a dust-embedded feedback phase, are controlled by a complex interplay between giant molecular cloud properties (masses and velocity dispersions) and galaxy morphology. We report relatively longer durations of the embedded phase of star formation in barred spiral galaxies, while this phase is significantly reduced in low-mass irregular dwarf galaxies. We discuss tentative trends with gas-phase metallicity, which may favor faster cloud dispersal at low metallicities.
Holographic Duality From Howe Duality, Anatoly Dymarsky, Johan Henriksson, Brian Mcpeak
Holographic Duality From Howe Duality, Anatoly Dymarsky, Johan Henriksson, Brian Mcpeak
Physics and Astronomy Faculty Publications
We discuss the holographic correspondence between 3d “Chern-Simons gravity” and an ensemble of 2d Narain code CFTs. Starting from 3d abelian Chern-Simons theory, we construct an ensemble of boundary CFTs defined by gauging all possible maximal subgroups of the bulk one-form symmetry. Each maximal non-anomalous subgroup is isomorphic to a classical even self-dual error-correcting code over ℤp × ℤp, providing a way to define a boundary “code CFT.” The average over the ensemble of such theories is holographically dual to Chern-Simons gravity, a bulk theory summed over 3d topologies sharing the same boundary. In the case of …
From Leaky Pipelines To Watering Cans, Samantha Fladd, Sarah Kurnick, Laura E. Heath-Stout, Nala K. Williams, Sarah Simeonoff, Sasha Buckser, Katelyn J. Bishop, Scott R. Hutson, Jessica Maclellan, Marie Matsuda, Sarah E. Oas, Jocelyne M. Ponce, Bruno Athie Teruel, Jaycee Castro, Breeanna Charolla, Adriana M. De León, Luisa Escobar Galo, Lydia D. Evans, Isabella N. Garcia, Kelsey Hoppes, Elena Lompe
From Leaky Pipelines To Watering Cans, Samantha Fladd, Sarah Kurnick, Laura E. Heath-Stout, Nala K. Williams, Sarah Simeonoff, Sasha Buckser, Katelyn J. Bishop, Scott R. Hutson, Jessica Maclellan, Marie Matsuda, Sarah E. Oas, Jocelyne M. Ponce, Bruno Athie Teruel, Jaycee Castro, Breeanna Charolla, Adriana M. De León, Luisa Escobar Galo, Lydia D. Evans, Isabella N. Garcia, Kelsey Hoppes, Elena Lompe
Anthropology Faculty Publications
Despite improvement over the past few decades, particularly for white, cisgender women, intersectional gender-based inequality remains prominent within anthropological archaeology and beyond. Building on critiques of the leaky pipeline metaphor laid out in the introduction to this themed issue, and drawing on Black, Indigenous, and Posthumanist Feminisms, we advocate for a metaphorical shift focused on care, inclusivity, and diversity—that of a garden. The garden metaphor provides a way to express and explore the complex and intertwined ways disciplinary norms, institutions, and individuals structure and shape experiences in archaeology. After reviewing the garden metaphor and summarizing previous suggestions for improving equity …