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Comparison Of Machine Learning Models For Colon Cancer Survival: Predictive Modeling Approach, Reuben Adatorwovor, Motolani E. Ogunsanya, Bin Huang, Richard Charnigo, Olufunmilola Abraham Jan 2025

Comparison Of Machine Learning Models For Colon Cancer Survival: Predictive Modeling Approach, Reuben Adatorwovor, Motolani E. Ogunsanya, Bin Huang, Richard Charnigo, Olufunmilola Abraham

Biostatistics Faculty Publications

Background: Colon cancer is a leading cause of cancer-related deaths worldwide, with survival influenced by risk factors, treatment type, and patient characteristics. Traditional statistical models, such as Kaplan-Meier curves, have been widely used to estimate survival probabilities. However, these models often have difficulty handling complex interactions, covariates, and nonlinear relationships between risk factors. Recently, machine learning (ML) techniques have emerged as promising tools for improving survival prediction by handling large covariates and capturing complex patterns.

Objective: This study compares several ML models to accurately estimate colon cancer survival by leveraging data from the Kentucky Cancer Registry. By identifying key risk …


Incident Atherosclerotic Cardiovascular Disease Among Veterans By Gender Identity: A Cohort Study, Carl G. Streed Jr., Meredith S. Duncan, Kory R. Heier, T. Elizabeth Workman, Lauren B. Beach, Guneet K. Jasuja, Hill L. Wolfe, Landon D. Hughes, John R. O’Leary, Melissa Skanderson, Joseph L. Goulet Jan 2025

Incident Atherosclerotic Cardiovascular Disease Among Veterans By Gender Identity: A Cohort Study, Carl G. Streed Jr., Meredith S. Duncan, Kory R. Heier, T. Elizabeth Workman, Lauren B. Beach, Guneet K. Jasuja, Hill L. Wolfe, Landon D. Hughes, John R. O’Leary, Melissa Skanderson, Joseph L. Goulet

Biostatistics Faculty Publications

Background: Transgender and gender diverse (trans) populations are at elevated risk for atherosclerotic cardiovascular disease (ASCVD).

Objective: Measure the association of gender identity and gender-affirming hormone therapy (GAHT) with ASCVD outcomes.

Design: Cohort study.

Participants: Over 1 million veterans receiving care in the Veterans Health Administration.

Main Measures: Gender identity was identified via a validated natural language processing (NLP) algorithm. Incident ASCVD (acute myocardial infarction, ischemic stroke, or revascularization after the baseline date) was identified via International Classification of Diseases diagnosis codes among veterans without prevalent ASCVD. We calculated sample statistics stratified by gender identity and used Cox proportional hazard …


Relevance And Reciprocity: Fostering Meaningful Inquiry In The Social Studies Classroom, Christy Cartner Jan 2025

Relevance And Reciprocity: Fostering Meaningful Inquiry In The Social Studies Classroom, Christy Cartner

Theses and Dissertations--Curriculum and Instruction

This dissertation investigates the factors contributing to students' perceptions of meaningful inquiry. After using the C3 Framework and designing instruction using the Inquiry Design Model for a decade, I wanted to better understand the students' experience to fine-tune how I implement inquiry in the classroom.

Article 1 was written for Social Education and describes the year of IDM blueprints that I designed to loop the concept of equality through units spanning the social studies disciplines of sociology, history, civics, geography, and economics. Through designing and facilitating these inquiries, I discovered my problem of practice, which was how to better engage …


International School Leaders’ Lived Experiences Of Crises And Perceptions Of Trust, Shary L. Marshall Jan 2025

International School Leaders’ Lived Experiences Of Crises And Perceptions Of Trust, Shary L. Marshall

Theses and Dissertations--Educational Leadership Studies

International school leaders worldwide have navigated their schools through a variety of crises. Their unique lived experiences offer insights into the role of trust in leadership, particularly during times of crisis.

This qualitative study employed a phenomenological approach to explore the lived experiences of 12 experienced international school leaders. Data was collected through semi-structured interviews. Using the theoretical lenses of authentic leadership, sensemaking, loose coupling, and crisis leadership, this study illuminates the central role of trust in leading schools through crises.

Three significant themes emerged from the analysis. First, trust is foundational to leadership and is built through intentional, transparent …


Increasing Daily Living Independence Using Video Modeling In Middle School Students With Intellectual Disability, Pamela J. Sullivan Jan 2025

Increasing Daily Living Independence Using Video Modeling In Middle School Students With Intellectual Disability, Pamela J. Sullivan

Theses and Dissertations--Educational Leadership Studies

This study used a multiple probe across participants design to (a) evaluate the use of a mobile device (i.e., iPad) for video modeling to increase functional daily living skills and (b) evaluate the use of system of least prompts to teach students to self-instruct. In baseline, the classroom teacher asked participants to start their tasks and collected performance data. In the technology training condition, the teacher implemented a system of least prompts procedure to teach participants to initiate use of the iPad, navigate to a training video model, pause/play videos of training tasks, and perform the modeled training tasks. After …


The Role Of Cooperative Extension In Community Development: A Study Of Success Stories And Leadership Practices, George Grant Jan 2025

The Role Of Cooperative Extension In Community Development: A Study Of Success Stories And Leadership Practices, George Grant

Theses and Dissertations--Educational Leadership Studies

The Cooperative Extension System (CES) plays a vital role in community education and development across the United States. CES agents and specialists work directly with community members to identify needs, mobilize existing assets, and empower action. Despite the overlap in the fields of CES and community development, few studies have systematically analyzed the specific practices used by extension personnel who act as facilitators of change within communities. To address this gap in knowledge, a qualitative study was conducted using directed content analysis of CES success stories published through the University of Kentucky to identify practices used among two integral positions …


A Survey Study Of Professional Competencies For Resident Directors: Perspectives From Resident Directors And Supervisors, Lauren Doerner Jan 2025

A Survey Study Of Professional Competencies For Resident Directors: Perspectives From Resident Directors And Supervisors, Lauren Doerner

Theses and Dissertations--Educational Leadership Studies

Resident directors (RDs) play a critical role in the success of residence life programs on college campuses. However, there is limited research on the professional competencies necessary for success in this role. This study explores the relationship between the ACPA and NASPA professional competencies RDs and their supervisors identify as most critical for RD success. In this study, RDs and their supervisors ranked key competencies, assessed RDs' mastery of these competencies, and RDs identified how they acquired them. Using a survey research design, quantitative data were collected from RDs and their supervisors at Research I institutions in the southeastern United …


Navigating Stress In Higher Education Leadership: The Role Of Mindful Meditation For Women Administrators, Christine T. Harper Jan 2025

Navigating Stress In Higher Education Leadership: The Role Of Mindful Meditation For Women Administrators, Christine T. Harper

Theses and Dissertations--Educational Leadership Studies

Women higher education administrators encounter distinct stressors which can significantly impact wellbeing and lead to burnout. These challenges include implicit bias, difficulty achieving work-life balance, and increasing institutional expectations. This study utilizes a Mixed Methods Action Research (MMAR) framework to assess stress levels, trait mindfulness, coping mechanisms, and the effectiveness of a structured mindfulness-based intervention. While the quantitative analysis revealed only a slight increase in trait mindfulness and no notable reduction in stress levels, the qualitative findings showcased meaningful personal benefits to the participants. They reported heightened awareness of stress triggers, improved emotion regulation, and an ability to apply the …


Crossing Borders, Breaking Barriers: The Transformative Journey Of First-Generation Students Abroad, Stephen Farley Jan 2025

Crossing Borders, Breaking Barriers: The Transformative Journey Of First-Generation Students Abroad, Stephen Farley

Theses and Dissertations--Educational Policy Studies and Evaluation

First-generation students are underrepresented in study abroad programming, both nationally and at the University of Kentucky. To address participation barriers and the resulting opportunity gap for first-generation students, the University of Kentucky designed and implemented an innovative study abroad program for first-generation students titled “Explore First: Careers, Cultures, and Connections.” This specially-designed program sought to provide participants with the academic, social, and professional benefits associated with education abroad experiences, including greater self-efficacy, sense of belonging, intercultural competence, and career exploration and preparation. This mixed methods study examines these intended outcomes of Explore First. Drawing from quantitative surveys administered pre-, mid- …


Scholars And Schisms: A History Of Antebellum Conflicts Over Slavery At Central Kentucky Liberal Arts Colleges, Wyatt M. Driskell Jan 2025

Scholars And Schisms: A History Of Antebellum Conflicts Over Slavery At Central Kentucky Liberal Arts Colleges, Wyatt M. Driskell

Theses and Dissertations--Educational Policy Studies and Evaluation

This dissertation explores how debates about slavery impacted constituents at four early liberal arts colleges (Berea, Centre, Georgetown, and Transylvania) in antebellum central Kentucky. In addition to focusing on how these colleges participated in, responded to, and helped shape regional debates over slavery, this study also explores how college leaders’ consideration of slavery was intertwined with religion, politics, and the financial pressures inherent in operating a 19th-century institution of higher education. From archival research, I argue that these constituents were not passive participants in this process. In addition to considering slavery from religious, moral, or political perspectives, leaders advanced positions …


Teaching Peers To Increase Their Use Of Responsive Interaction Strategies With Children Who Use Aac, Andrea Weidman Jan 2025

Teaching Peers To Increase Their Use Of Responsive Interaction Strategies With Children Who Use Aac, Andrea Weidman

Theses and Dissertations--Education Sciences

Students enrolled in peer mentoring programs require guidance in understanding how to effectively and appropriately communicate and support students who communicate using augmentative and alternative communication (AAC) devices. This project evaluated the effectiveness of a peer training protocol on the count of observed responsive interaction strategies used by middle schoolers in an inclusive classroom setting. These strategies increase confidence in communication partners and aide in development of meaningful relationships between students with diverse communication needs.


Restorative Justice In Early Childhood Education: A Professional Development Model And Observational Study Of Classroom Implementation, Sarah Cummins Jan 2025

Restorative Justice In Early Childhood Education: A Professional Development Model And Observational Study Of Classroom Implementation, Sarah Cummins

Theses and Dissertations--Education Sciences

This three-article dissertation explores the use of restorative justice (RJ) in educational settings, with a specific focus on early childhood programs. Restorative justice is a conflict resolution approach that prioritizes repairing harm, restoring trust, and empowering individuals to self-advocate rather than relying solely on punitive measures. While research has demonstrated the success of RJ in middle and high schools, and to some extent in elementary schools, limited attention has been given to its application in early childhood education. This dissertation examines the potential benefits of RJ in early childhood classrooms, including fostering social-emotional learning, student-led conflict resolution, and a positive …


The Journey To Becoming An Authentic Leader In A Technical Nursing Institute In Egypt Using Autoethnographic And Descriptive Phenomenological Approaches Through A Three-Article Style Dissertation., Sylvia Basta Jan 2025

The Journey To Becoming An Authentic Leader In A Technical Nursing Institute In Egypt Using Autoethnographic And Descriptive Phenomenological Approaches Through A Three-Article Style Dissertation., Sylvia Basta

Theses and Dissertations--Education Sciences

Authentic leaders in nursing higher education significantly influence the organizational climate, fellow faculty members, and, ultimately, students. They develop in a climate of well-being, allowing them to reflect self-awareness, have a balanced approach to processing self-relevant information, have an internalized moral perspective, and have relational transparency. Positive emotions, engagement, relationships, meaning, and accomplishment are the foundations of this climate. Moreover, authentic leaders grow through their supported Psychological Capacities (PsyCap) of hope, efficacy, resilience, and optimism. Exploring the essence of developing into an authentic leader within an Egyptian nursing higher education context is addressed in this dissertation, which consists of three …


Exploratory Analysis Of Gait Mechanics In Farmers, Mariana V. Jacobs, Kate N. Jochimsen, Jody L. Clasey, Michael A. Samaan Jan 2025

Exploratory Analysis Of Gait Mechanics In Farmers, Mariana V. Jacobs, Kate N. Jochimsen, Jody L. Clasey, Michael A. Samaan

Kinesiology and Health Promotion Faculty Publications

Farmers may be at a higher risk of developing hip osteoarthritis (OA) due to the high demands of their occupation. To the authors’ knowledge, the gait patterns of farmers that may be associated with hip joint degeneration have yet to be analyzed. Therefore, this study compares gait mechanics between farmers and non-farmers (controls). It is hypothesized that farmers would exhibit altered lower extremity joint mechanics during walking when compared to matched controls. This exploratory study included five farmers and five sex-, age-, and body mass index (BMI)-matched controls. A 3D gait analysis was performed while study participants walked at a …


A Comprehensive Evaluation Of Thigh Mineral-Free Lean Mass Measures Using Dual Energy X-Ray Absorptiometry (Dxa) In Young Children, Trey R. Naylor, Mariana V. Jacobs, Michael A. Samaan, Laura C. Murphy, Douglas J. Schneider, Margaret O. Murphy, Hong Huang, John A. Bauer, Jody L. Clasey Jan 2025

A Comprehensive Evaluation Of Thigh Mineral-Free Lean Mass Measures Using Dual Energy X-Ray Absorptiometry (Dxa) In Young Children, Trey R. Naylor, Mariana V. Jacobs, Michael A. Samaan, Laura C. Murphy, Douglas J. Schneider, Margaret O. Murphy, Hong Huang, John A. Bauer, Jody L. Clasey

Kinesiology and Health Promotion Faculty Publications

This study aimed to (1) demonstrate the intra- and interrater reliability of quadriceps (QUADS) and hamstring (HAMS) mineral-free lean (MFL) mass measures using DXA scanning, (2) determine the association of total thigh MFL mass measures with MFL mass measures of the hamstrings and quadriceps combined and (3) analyze the association between total thigh MFL mass and total body MFL mass measures. A total of 80 young children (aged 5 to 11 yrs) participated and unique regions of interest were created using custom analysis software with manual tracing of the QUADS, HAMS, and total thigh MFL mass measures. Repeated-measure analysis of …


The Curious Case Of The Law Review Editor: A Study Of Higher Education's Peculiarly Powerful Students, David R. Wright Jan 2025

The Curious Case Of The Law Review Editor: A Study Of Higher Education's Peculiarly Powerful Students, David R. Wright

Theses and Dissertations--Educational Policy Studies and Evaluation

Many law students in their second or third year enroll in student-led, high-impact co-curricular programs such as law journals, moot court teams, and trial competition teams. Law journals particularly demand significant portions of students’ time and energy, especially for students holding Editor-in-Chief positions on a journal. Much has been written about law journals as institutions or about their utility in modern legal education; but little is known about the actual expectations and experiences of the students leading them. Few, if any, studies exist examining the student experience in law journal leadership. How student editors spend their time running their journal …


Investigating The Psychometric Properties Of A Set Of Local Stem Literacy Instruments In Rasch Model, Lijun Shen Jan 2025

Investigating The Psychometric Properties Of A Set Of Local Stem Literacy Instruments In Rasch Model, Lijun Shen

Theses and Dissertations--Educational Policy Studies and Evaluation

This study investigates the psychometric features of the See Blue STEM literacy inventories (SBSTEMs, including the elementary version SB-E and the middle school version SB-M) to determine their validity in measuring STEM literacy. Using data from elementary and middle school students participating in the See Blue STEM camp in 2019 and 2021-22, this research employed the Rasch Partial Credit Model (PCM) to analyze item-level performance and identify DIF items across various demographic subgroups (race, gender, free-lunch status, and potential first-generation status) and camp delivery modes (online versus in-person). Results indicated that both the elementary (SB-E) and middle school (SB-M) versions …


Knee Health Is A Major Determinant Of Mobility Across The Healthspan, Brandon M. Peoples, Kenneth Harrison, Michael A. Samaan, Christopher B. Mobley, David T. Redden, Jaimie A. Roper Jan 2025

Knee Health Is A Major Determinant Of Mobility Across The Healthspan, Brandon M. Peoples, Kenneth Harrison, Michael A. Samaan, Christopher B. Mobley, David T. Redden, Jaimie A. Roper

Kinesiology and Health Promotion Faculty Publications

Knee health constitutes a pivotal determinant of locomotor function and overall mobility throughout the healthspan. Impairments in knee function lead to a series of biomechanical and physiological alterations that pose substantial public health challenges and economic burdens worldwide. This review synthesizes evidence that delineates the complex and multifaceted relationship between knee health and mobility, emphasizing the interplay across various domains in adult populations. Knee health is conceptualized as a dynamic, interconnected system whereby structural integrity, neuromuscular mechanisms, biomechanical adaptations, and functional mobility are intricately interrelated through cascades of mechanistic processes operating across different temporal stages. A comprehensive understanding of these …


Examining The Professional Noticing Skills, Attitudes Toward Mathematics, And Elementary Math Content Knowledge Of Preservice Elementary School Teachers Through The Noticing Numeracy Now Intervention, Johnathan T. Rogers Jan 2025

Examining The Professional Noticing Skills, Attitudes Toward Mathematics, And Elementary Math Content Knowledge Of Preservice Elementary School Teachers Through The Noticing Numeracy Now Intervention, Johnathan T. Rogers

Theses and Dissertations--Science, Technology, Engineering, and Mathematics (STEM) Education

Abstract: This quasi-experimental study examined the impact of the Noticing Numeracy Now intervention, an intervention focused on professional noticing of children’s conceptual development in whole number and arithmetic reasoning, on preservice elementary teachers’ professional noticing skills, attitudes toward mathematics, and elementary math content knowledge. This study was based off of a previous study and intervention created by Molly Fisher, Jonathan Thomas, Edna Schack, Cindy Jong and Janet Tassell. This study used a video-based professional noticing module, consisting of four lessons, situated in the pedagogies of practice framework. Within this study, 10 students (all preservice elementary teachers) at Kentucky State University …


Examples Of Storytelling In Tan Dun’S The Banquet Piano Sonata, Ni Zhan Jan 2025

Examples Of Storytelling In Tan Dun’S The Banquet Piano Sonata, Ni Zhan

Theses and Dissertations--Music

The Banquet is a 2006 Chinese martial arts film directed by Feng Xiaogang. Chinese-American composer Tan Dun was invited to create the film's original soundtrack. In 2016, Tan adapted the music from the soundtrack into a four-movement piano sonata, also titled The Banquet, using melodies from the original film score. This document examines The Banquet Piano Sonata’s connection to the film’s narrative. It explores ways in which the storytelling of the film is used in the sonata; this is accomplished through three key aspects depicted in the music: culture, atmosphere, and inner emotions.


Schubert Lieder For Solo Piano: From Liszt Transcriptions To An Original Adaptation, Changpeng Ti Jan 2025

Schubert Lieder For Solo Piano: From Liszt Transcriptions To An Original Adaptation, Changpeng Ti

Theses and Dissertations--Music

This document investigates Franz Liszt’s transcriptions of Schubert Lieder. Between 1838 and 1846, Liszt transcribed 56 songs (including standalone works and song cycles) by Franz Schubert into solo piano pieces. This document discusses compositional devices used in Liszt’s transcriptions and their relationship to Schubert’s vocal and piano writing as well as the original poetic text. Following the discussion on Liszt transcriptions, I present my own transcription of Schubert’s Im Frühling, D. 882, as an experiment in adapting vocal and poetic nuances into a solo piano piece inspired by the Liszt transcriptions.


Teacher Perceptions Of A Mindful-Based Social Emotional Group Drumming Curriculum: A Collective Case Study, Kristin Lewis Jan 2025

Teacher Perceptions Of A Mindful-Based Social Emotional Group Drumming Curriculum: A Collective Case Study, Kristin Lewis

Theses and Dissertations--Music

Educational researchers have discovered a connection between educator and student well-being. Educators need to cultivate these skills to effectively model social emotional learning (SEL). However, there is a shortage of resources for elementary general music educators that intentionally embed social emotional competencies in tandem with adhering to the National Core Arts Standards.

Therefore, the purpose of this study was to examine elementary music educators’ perceptions of a Mindfulness-Based Social Emotional Learning (MBSEL) group drumming curriculum and its impact on their own and their students’ social emotional competencies (SECs). The research questions were: (1) What are elementary music educators’ perceptions of …


James M. David’S Ghosts Of The Old Year: A Formal Analysis And Instructional Guide, Brian P. Froedge Dr. Jan 2025

James M. David’S Ghosts Of The Old Year: A Formal Analysis And Instructional Guide, Brian P. Froedge Dr.

Theses and Dissertations--Music

James David’s Ghosts of the Old Year (2016) is a significant work for wind ensemble which was performed at the American Bandmasters Association Convention in 2019 by the Colorado State University Wind Ensemble under the direction of Rebecca Phillips and at the 2019 Texas Music Educators Association Convention by the North Texas Wind Symphony under the direction of Eugene Migliaro Corporon. The piece was recorded by the North Texas Wind Symphony on the album titled noteworthy. Ghosts of the Old Year has also been performed by such prestigious ensembles as the University of Illinois Wind Orchestra, the University of Florida …


Anatomical Literacy And Body Mapping In Flute Performance: Strategies For Addressing And Preventing Upper Extremity Injuries, Lauren E. Wiedemer Jan 2025

Anatomical Literacy And Body Mapping In Flute Performance: Strategies For Addressing And Preventing Upper Extremity Injuries, Lauren E. Wiedemer

Theses and Dissertations--Music

This document investigates the benefits of incorporating the study of anatomy and Body Mapping into flute performance, specifically focusing on addressing and preventing injuries related to the upper extremities. As the physical demands on musicians continue to grow, this research advocates for recognizing flutists as "musical athletes.” It highlights the importance of anatomical literacy and somatic awareness in sustaining performance longevity. The practical applications of Body Mapping are explored in detail and presents strategies for alleviating strain and fostering ease of movement, supported by research and experiential insights. Pedagogical recommendations are offered to integrate these principles into flute instruction, helping …


A Comparison Of Informal Choral Singing Experiences, Christopher Powell Jan 2025

A Comparison Of Informal Choral Singing Experiences, Christopher Powell

Theses and Dissertations--Music

A traditional choir relies on the interest and participation of the population in communal singing. However, drawing willing participants into a traditional choir program can often prove challenging to music educators, community choir directors, and leaders of religious music programs. One of the most prevalent informal singing groups in the USA is Sacred Harp. Sacred Harp “singings” have been around since the early years of The Sacred Harp itself. These singings occur regularly in multiple locations across the country and around the world. These events have an open atmosphere and, despite the mostly Christian material, have no expectation of a …


Secondary String Students’ Perceptions Of The Role Of Self-Efficacy In Mitigating Their Musical Performance Anxiety: A Collective Case Study, Mary E. Henton Jan 2025

Secondary String Students’ Perceptions Of The Role Of Self-Efficacy In Mitigating Their Musical Performance Anxiety: A Collective Case Study, Mary E. Henton

Theses and Dissertations--Music

Musical Performance Anxiety (MPA) is a multifaceted psychological condition that arises before, during, or after musical performance and presents a significant obstacle for young musicians, particularly secondary string students. Closely linked to the spotlight effect and social anxiety, MPA has worsened among youth following the COVID-19 pandemic due to decreased social interaction, both of which have had adverse effects on students’ mental health. Despite teachers’ awareness of MPA’s prevalence, music education programs often lack instruction in specific coping mechanisms to address it, and many students do not seek support or treatment.

The purpose of this study was to describe the …


A Twenty-First Century Approach To Darius Milhaud's Saudades Do Brasil, Paige H. Crain Jan 2025

A Twenty-First Century Approach To Darius Milhaud's Saudades Do Brasil, Paige H. Crain

Theses and Dissertations--Music

French composer Darius Milhaud (1892-1974) lived in Rio de Janeiro, Brazil from February 1917 to November 1918. Milhaud’s experience in Rio was overwhelmingly positive, and several of his works were influenced by this period of his life, one being a suite for solo piano titled Saudades do Brasil, Op. 67. Inspired by Brazilian popular music, this piece is an example of exoticism, a trend of writing music based on cultures other than the composer’s own. Considering that exoticism historically has the potential to perpetuate harmful stereotypes or generate false information, this research delves into Saudades do Brasil, exploring …


Professional Experiences Of Disabled Music Therapists: An Adapted Multiple Case Study, August Lily Tuggle Jan 2025

Professional Experiences Of Disabled Music Therapists: An Adapted Multiple Case Study, August Lily Tuggle

Theses and Dissertations--Music

Literature about disability often focuses on disabled people as recipients of professional services and there is scant literature about disabled professionals. Although music therapists work primarily with disabled individuals, there is little research on or from the perspectives of disabled music therapists. A growing body of qualitative research, grey literature, and media platforms provides perspectives from the disability community regarding music therapy. Disabled individuals both within and outside the profession critique common music therapy attitudes and practices that conflict with the expressed needs of the disability community. However, much of this literature contains the perspectives of one individual or a …


Expression Of Dementia Biomarkers In Appalachian And Non-Appalachian Elvo Patients During Thrombectomy, Neha Anil, Christopher J. Mclouth, Hunter S. Hazelwood, Elise Dahlke, Jacqueline A. Frank, Nathan Millson, Mais Al-Kawaz, Jordan P. Harp, Will Cranford, Shivani Pahwa, David Dornbos, Justin F. Fraser, Keith R. Pennypacker Jan 2025

Expression Of Dementia Biomarkers In Appalachian And Non-Appalachian Elvo Patients During Thrombectomy, Neha Anil, Christopher J. Mclouth, Hunter S. Hazelwood, Elise Dahlke, Jacqueline A. Frank, Nathan Millson, Mais Al-Kawaz, Jordan P. Harp, Will Cranford, Shivani Pahwa, David Dornbos, Justin F. Fraser, Keith R. Pennypacker

Biostatistics Faculty Publications

Background/Context: Vascular Cognitive Impairment and Dementia (VCID) affects 25-30% of stroke patients and includes cognitive impairments caused by vascular injury, such as post-stroke dementia. Rehabilitation has the potential to improve the quality of life for patients at risk of developing dementia. However, there is currently no reliable method to identify those at risk of dementia after a stroke. Several biomarkers, including ADRD (Alzheimer’s disease and related dementias) biomarkers (Ab, tau, NfL, and GFAP) and angiogenic factors (VEGF, Flt-1, Tie-2, PIGF, and FGF) have been associated with the development of dementia. Populations in Appalachia experience a higher incidence of stroke and …


The Research Examining Factors Associated With The Opioid Crisis Among Urban Adults (Refocus), Mona K.M. Goggins, Paige Orphé, Jovonna Atkinson, Brittany Miller-Roenigk, Kaylee A. Palomino, Danelle Stevens-Watkins Jan 2025

The Research Examining Factors Associated With The Opioid Crisis Among Urban Adults (Refocus), Mona K.M. Goggins, Paige Orphé, Jovonna Atkinson, Brittany Miller-Roenigk, Kaylee A. Palomino, Danelle Stevens-Watkins

Educational, School, and Counseling Psychology Faculty Publications

Introduction: Deaths due to opioid-related overdoses have increased across the United States. Specifically in the state of Kentucky, African Americans are the only population that continues to experience an increase in opioid-related deaths. Previous literature highlights African Americans having unique drug use patterns due to systematic barriers and how these barriers limit access to protective factors and substance use treatment. The current study aims to specify patterns of African American non-medical prescription opioid use (NMPOU) and how these patterns may differ based on biological sex and generational cohort. Also, this study plans on using this data on patterns to inform …