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Articles 781 - 810 of 12089
Full-Text Articles in Entire DC Network
Kentucky Geological Survey Landslide Inventory [2024], Matthew M. Crawford, Evelyn M. Bibbins, Hudson J. Koch
Kentucky Geological Survey Landslide Inventory [2024], Matthew M. Crawford, Evelyn M. Bibbins, Hudson J. Koch
Research Data--KGS
The KGS landslide inventory provides the locations of known landslides and areas susceptible to debris flows. Various types of landslides are represented including slides, flows, rockfalls, and creep. The data are available as ArcGIS geodatabase feature classes. Landslide locations and associated attributes are compiled from Kentucky Geological Survey research, published maps, state and local government agencies, the public, and media reports. A confidence ranking system assigns a value to each feature. A description of the feature classes is here: https://kgs.uky.edu/kgsmap/helpfiles/landslide_help.shtm
The inventory viewed in a GIS with geology, soils, slope or other terrain-based data can serve as a basis for …
Looking Back: The Colored Reading Rooms In Kentucky Before 1900: Let Me Free!, Reinette F. Jones
Looking Back: The Colored Reading Rooms In Kentucky Before 1900: Let Me Free!, Reinette F. Jones
Library Faculty and Staff Publications
No abstract provided.
Analysis And Design Of Synchronous Machines With Reluctance Rotor And Pm Stator Combined Excitation, Oluwaseun A. Badewa, Dan M. Ionel
Analysis And Design Of Synchronous Machines With Reluctance Rotor And Pm Stator Combined Excitation, Oluwaseun A. Badewa, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
This paper studies motors that are part of a general class of synchronous machines with stator-only excitation including those that may be referred to in recent literature as of the flux switching, variable flux reluctance, or hybrid excitation type. In the studied example machine, the active stator has circumferentially magnetized spoke-type PMs and concentrated toroidal coils for improved slot fill and shortened end turns. A systematic analysis of the mmf produced by the toroidal coils in the stator and open-circuit airgap flux is developed to define feasible polarities of this synchronous motor and to establish that the dominant pole pair …
Kentucky Traffic Collision Facts Calendar Year 2023 Report, Paul Ross, Eric Green, Chris Blackden, Kenneth R. Agent, Chris Van Dyke
Kentucky Traffic Collision Facts Calendar Year 2023 Report, Paul Ross, Eric Green, Chris Blackden, Kenneth R. Agent, Chris Van Dyke
Kentucky Transportation Center Research Report
No abstract provided.
Analysis Of Traffic Crash Data In Kentucky 2019-2023, Paul Ross, Eric Green, Chris Blackden, Christopher Van Dyke, Teng Wang, Mohammad Majidi
Analysis Of Traffic Crash Data In Kentucky 2019-2023, Paul Ross, Eric Green, Chris Blackden, Christopher Van Dyke, Teng Wang, Mohammad Majidi
Kentucky Transportation Center Research Report
No abstract provided.
New Loads And Service Factors For Distribution Transformers Following The Transition To High-Efficiency Heat Pumps, Solar Pv, And Ev Charging, Steven B. Poore, Rosemary E. Alden, Timothy Rooney, Dan M. Ionel
New Loads And Service Factors For Distribution Transformers Following The Transition To High-Efficiency Heat Pumps, Solar Pv, And Ev Charging, Steven B. Poore, Rosemary E. Alden, Timothy Rooney, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
Replacement of conventional high-power appliances including heating ventilation and air-conditioning (HVAC) and resistive electric water heaters (EWHs) with heat pumps is expected to be implemented long-term to increase energy efficiency. Even with efficiency upgrades, future residential power demand may rise due to increasing electric vehicle (EV) penetration. Extensive experimental data from field demonstrators and regional utilities as well as thousands of synthetically generated loads are utilized to investigate the effect of heat pumps, EV charging, and distributed solar PV on residential power demand and distribution transformers. Values are established for typical rating distribution and connection to multiple houses to study …
Solar Pv And Ev Controls For Reactive Power Support On Large Distribution Systems Modeled With Experimental And Synthetic Loads, Rosemary E. Alden, Malcolm Mcculloch, Dan M. Ionel
Solar Pv And Ev Controls For Reactive Power Support On Large Distribution Systems Modeled With Experimental And Synthetic Loads, Rosemary E. Alden, Malcolm Mcculloch, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
Changes to electric power distribution equipment may be needed to adapt to distributed energy resources (DERs) such as solar photovoltaic (PV) generation and electric vehicle (EV) batteries. Within this paper, an optimization methodology for reactive power support (RPS) controls managed by utilities for EV bi-directional charger power factor and improve substation power quality and voltage across the system is proposed. An IEEE benchmark distribution system, the 123 node test feeder, is modified to include 1,765 experimental residential profiles at typical, high resolution of 15min from smart meters, solar PV generation calculated from weather data, and EV modules based on driver …
Optimal Design And Comparison Of Synchronous Machines With Inner And Outer Reluctance Rotors And Pm Or Dc Stator Combined Excitation, Oluwaseun A. Badewa, Ali Mohammadi, Donovin D. Lewis, Dan M. Ionel
Optimal Design And Comparison Of Synchronous Machines With Inner And Outer Reluctance Rotors And Pm Or Dc Stator Combined Excitation, Oluwaseun A. Badewa, Ali Mohammadi, Donovin D. Lewis, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
This paper presents an optimal design and comparative analysis for a toroidally wound reluctance rotor synchronous machine with either PM or DC excitation in the stator. The prototype of the PM version is experimentally evaluated, and its results are used to validate the model of the DC version as they share the same topology. The stator DC-excited synchronous (SDCES) motor is optimized at different outer diameters using large-scale multi-objective differential evolution (DE) and comparatively analyzed at power ratings typical for electric traction and propulsion applications. Its performance at reduced temperatures shows increased efficiency and goodness due to reduced losses, and …
Design Of High-Power Polyphase Pcb Coil Systems For Wireless Power Transfer, Donovin Lewis, Lucas Gastineau, Omer Onar, Malcolm Mcculloch, John F. Eastham, Dan M. Ionel
Design Of High-Power Polyphase Pcb Coil Systems For Wireless Power Transfer, Donovin Lewis, Lucas Gastineau, Omer Onar, Malcolm Mcculloch, John F. Eastham, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
Printed circuit board (PCB) coils have been pro- posed prior for implementation as inductive wireless charging coils to minimize size and cost. Utilization of PCBs can allow for a reduced cost, improved manufacturability, and a wide range of geometric customization options. To circumvent material limitations on insulation and thermal performance, parallel paths can be implemented to divide the current per path accordingly. Within this paper, an unconventional high power PCB coil is designed employing all possible techniques for wiring with axial and radial parallel paths with equivalent transposition to minimize circulating currents. Design studies are simulated in 3D finite element …
Two-Level Design Optimization Of Ac Machines With Dc Stator Excitation And Minimal Torque Ripple Using Reluctance Rotor Profile Shaping, Ali Mohammadi, Oluwaseun A. Badewa, Yaser Chulaee, Dan M. Ionel
Two-Level Design Optimization Of Ac Machines With Dc Stator Excitation And Minimal Torque Ripple Using Reluctance Rotor Profile Shaping, Ali Mohammadi, Oluwaseun A. Badewa, Yaser Chulaee, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
Torque ripple mitigation in electric machines is important for a smooth and stable operation, minimize mechanical vibrations, and enhance the overall performance. In this paper, a novel two-level optimization method is proposed for the design of synchronous flux-switching and hybrid excitation machines with an innovative multi-point spline shaping method to minimize the torque ripple. This study uses models that are validated by experimental tests from a prototype with similar topology, and exemplifies the aforementioned optimization process on a 28 pole machine. The analysis results indicate that the torque ripple can be substantially reduced with improved electromagnetic torque of the electric …
Design Of High-Power Polyphase Pcb Coil Systems For Wireless Power Transfer, Donovin D. Lewis, Lucas Gastineau, Omer Onar, Malcolm Mcculloch, John F. Eastham, Dan M. Ionel
Design Of High-Power Polyphase Pcb Coil Systems For Wireless Power Transfer, Donovin D. Lewis, Lucas Gastineau, Omer Onar, Malcolm Mcculloch, John F. Eastham, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
Printed circuit board (PCB) coils have been pro- posed prior for implementation as inductive wireless charging coils to minimize size and cost. Utilization of PCBs can allow for a reduced cost, improved manufacturability, and a wide range of geometric customization options. To circumvent material limitations on insulation and thermal performance, parallel paths can be implemented to divide the current per path accordingly. Within this paper, an unconventional high power PCB coil is designed employing all possible techniques for wiring with axial and radial parallel paths with equivalent transposition to minimize circulating currents. Design studies are simulated in 3D finite element …
Model Predictive Control Of 5l-Anpc Inverter Fed Coreless Afpm Motor With Mitigated Cmv In Electric Aircraft Propulsion, Farzad Y. Notash, Matin Vatani, Jiangbiao He, Dan M. Ionel
Model Predictive Control Of 5l-Anpc Inverter Fed Coreless Afpm Motor With Mitigated Cmv In Electric Aircraft Propulsion, Farzad Y. Notash, Matin Vatani, Jiangbiao He, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
This paper proposes a fast model predictive control (FMPC) method without weighting factors and mitigated common-mode voltage (CMV) for a five-level active neutral point clamped (5L-ANPC) inverter-fed electric aircraft propulsion system with a coreless axial flux permanent magnet (CAFPM) motor. This motor is specifically designed for electric aircraft propulsion through a combined electromagnetic and thermal evaluation, benefiting from a high specific power density, efficiency, and integrated thermal management system. The proposed method utilizes the deadbeat approach to calculate the reference voltage vector and compensate for the one-time interval delay between the predicted and applied switching commands. The angle and amplitude …
Analytical And Fe Modeling For The Design Of Coreless Axial Flux Machines With Halbach Array And Surface Pm Rotors, Matin Vatani, Yaser Chulaee, John F. Eastham, Dan M. Ionel
Analytical And Fe Modeling For The Design Of Coreless Axial Flux Machines With Halbach Array And Surface Pm Rotors, Matin Vatani, Yaser Chulaee, John F. Eastham, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
This paper introduces a rapid analytical modeling approach for coreless axial flux permanent magnet (AFPM) machines featuring surface-mounted and Halbach PM array rotors. The methodology employs a 2D model at an arbitrary diameter of the machine and converts AFPM machines into an equivalent linear machine. Initially, equations for PM flux density, accounting for harmonic content, are developed for both rotor types. Subsequently, a force equation is derived for the 2D equivalent machine based on the Lorentz force equation and the stator winding factor. In the final step, a torque equation at an arbitrary diameter—specifically, the average diameter in this paper—is …
Multi-Disk Coreless Axial Flux Permanent Magnet Synchronous Motors With Surface Pm And Halbach Array Rotors For Electric Aircraft Propulsion, Matin Vatani, John F. Eastham, Dan M. Ionel
Multi-Disk Coreless Axial Flux Permanent Magnet Synchronous Motors With Surface Pm And Halbach Array Rotors For Electric Aircraft Propulsion, Matin Vatani, John F. Eastham, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
This paper presents multiple single- and multi-disk coreless axial flux permanent magnet (AFPM) motors, focusing on specific power density and reliability for electric aircraft propulsion. Several 3D finite element analysis (FEA) parametric studies were conducted to assess the geometric impacts on a single-disk coreless AFPM motor featuring two separate stators and a double-sided Halbach array rotor configuration. These studies form the foundation for the design of both single and multi-disk machines. Single-disk coreless AFPM motors with rotor back iron embedded between the stators, offering magnetically decoupled stators, are subsequently introduced. The paper concludes by presenting four multi-disk coreless AFPM motor …
Multi-Wound Axial Flux Generators With Halbach Array Rotors, Matin Vatani, Yaser Chulaee, John F. Eastham, Xiaoze Pei, Dan M. Ionel
Multi-Wound Axial Flux Generators With Halbach Array Rotors, Matin Vatani, Yaser Chulaee, John F. Eastham, Xiaoze Pei, Dan M. Ionel
Electrical and Computer Engineering Graduate Research
This paper presents three coreless axial flux permanent magnet (AFPM) generator topologies that feature magnetically and electrically decoupled outputs using a single prime mover. The proposed topologies include: (1) two separate generators mounted on the same shaft, (2) a nested configuration with a smaller generator inside a larger one, and (3) a multi-wound generator with two sets of windings and different pole numbers for each rotor side. The multi-wound generator is selected for further investigation due to its superior power-to-volume ratio and the advantage of utilizing a single structure for stator cooling. The airgap magnetic flux density equation is derived …
The Undergraduate Engineering Mental Health Help-Seeking Instrument (Ue-Mh-Hsi): Development And Validity Evidence, Joseph H. Hammer, Courtney J. Wright, Melanie E. Miller, Sarah A. Wilson
The Undergraduate Engineering Mental Health Help-Seeking Instrument (Ue-Mh-Hsi): Development And Validity Evidence, Joseph H. Hammer, Courtney J. Wright, Melanie E. Miller, Sarah A. Wilson
Chemical and Materials Engineering Faculty Publications
Background: Undergraduate engineering students experiencing distress are less likely than peers to ask for professional help. A population-specific instrument to facilitate the identification of factors that influence mental healthcare utilization could guide development and testing of interventions to increase help seeking.
Purpose: We used mixed methods guided by the Integrated Behavioral Model (IBM) to develop and evaluate the Undergraduate Engineering Mental Health Help-Seeking Instrument (UE-MH-HSI).
Method: First, we adapted existing measures of mental health help-seeking intention and mechanisms (i.e., attitudes, perceived norm: injunctive, perceived norm: descriptive, personal agency: autonomy, personal agency: capacity). Second, we coded qualitative interviews (N = 33) …
Bacillus Thuringiensis Cry14a Family Proteins As Novel Anthelmintics Against Gastrointestinal Nematode Parasites, Duy Hoang, Kelly Flanagan, Qian Ding, Nicholas R. Cazeault, Hanchen Li, Stefani Díaz-Valerio, Florentina Rus, Esther A. Darfour, Elizabeth Kass, Katherine H. Petersson, Martin Krarup Nielsen, Heiko Liesegang, Gary R. Ostroff, Raffi V. Aroian
Bacillus Thuringiensis Cry14a Family Proteins As Novel Anthelmintics Against Gastrointestinal Nematode Parasites, Duy Hoang, Kelly Flanagan, Qian Ding, Nicholas R. Cazeault, Hanchen Li, Stefani Díaz-Valerio, Florentina Rus, Esther A. Darfour, Elizabeth Kass, Katherine H. Petersson, Martin Krarup Nielsen, Heiko Liesegang, Gary R. Ostroff, Raffi V. Aroian
Veterinary Science Faculty Publications
Bacillus thuringiensis crystal (Cry) proteins have been expressed in commercial transgenic crops for nearly 30 years, providing safe and effective control of insect pests and significantly reducing the application of hazardous chemical pesticides. B. thuringiensis crystal proteins have also been shown to target parasitic nematodes, including plant parasitic nematodes. Recently, transgenic soybean crops expressing Cry14Ab have been shown to provide control against the soybean cyst nematode Heterodera glycines, marking the first time a crystal protein is being commercialized in transgenic crops for control of a nematode pest. However, apart from H. glycines and the free-living nematode, Caenorhabditis elegans, the breadth …
Evaluation Of Kentucky’S Driver Focus Camera System, David Leddy, Brian Beaven, Xiaobing Li, Andrew Martin, Jennifer Walton, Chris Van Dyke
Evaluation Of Kentucky’S Driver Focus Camera System, David Leddy, Brian Beaven, Xiaobing Li, Andrew Martin, Jennifer Walton, Chris Van Dyke
Kentucky Transportation Center Research Report
Commercial motor vehicle (CMV) drivers who engage in federally prohibited activities such as not wearing safety belts, using hand-held mobile phones, or texting while driving endanger themselves and imperil the well-being of everyone who occupies the surrounding roadway environment. Unfortunately, conventional CMV inspection routines fail to detect many of these violations because inspectors have difficulty obtaining a clear view of truck cab interiors from inspection facilities. Recognizing it is critical to improve enforcement of Federal Motor Carrier Safety Regulations, this project evaluated the performance of a Driver Focus Camera System (DFCS) at an inspection facility on Interstate 75 northbound in …
2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute
2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute
Kentucky Water Resources Annual Symposium
The program and proceedings contains details of the 2024 Kentucky Water Resources Symposium, including presentations, award winners, and poster presentations.
This symposium was planned and conducted as a part of the state water resources research institute annual program that is supported by Grant/Cooperative Agreement Number G21AP10631-02 from the United States Geological Survey (USGS). The contents of this proceedings document and the views and conclusions presented at the symposium are solely the responsibility of the individual authors and presenters and do not represent the official views of the USGS or of the symposium organizers and sponsors. This publication is produced with …
2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute
2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute
Kentucky Water Resources Annual Symposium
No abstract provided.
Genetically Engineer Protection Against Viruses And Fungi, John Fitchen, Roger N. Beachy
Genetically Engineer Protection Against Viruses And Fungi, John Fitchen, Roger N. Beachy
IGC Proceedings (1977-2023)
The first examples of plant genetic engineering for disease resistance were for the control of virus diseases. Plants that were transformed with a gene to express the coat protein of tobacco mosaic virus (TMV) were shown to have increased resistance to infection by TMV. This approach, referred to as coat protein-mediated resistance (CP-MR), has been applied to give protection against at least 35 different viruses, belonging to 12 virus groups in at least 13 plant species. Field trials of some of these examples have demonstrated that CP-MR can effectively protect plants under field conditions. Other viral genes have also been …
Transfer Of Genes Encoding Proteins With High Nutritional Value Into Pasture Legumes, W C. Mcnabb, C Higgins, L Tabe, T J.V Higgins
Transfer Of Genes Encoding Proteins With High Nutritional Value Into Pasture Legumes, W C. Mcnabb, C Higgins, L Tabe, T J.V Higgins
IGC Proceedings (1977-2023)
Gene transfer systems for the forage legumes, subterranean clover (Trlfolium subterraneum) and lucerne (Medicago saltva) have been developed and optimised for current commercial cultivars. A disarmed binary vector derived from the Agrobacterium tunefaciens tumour• inducing plasmid has been used to deliver a selectable marker gene conferring resistance to phosphinothricin (the active ingredient in the herbicide, Basta) and a series of chimeric gene constructs encoding proteins that are rich in sulphur amino acids and resistant to rumen degradation. Transgenic plants expressing a gene encoding either ovalbumin or a sunflower albumin have been obtained and analyzed with respect to …
Genetic Engineering Of Pasture Legume And Grasses For Reduced Lignin Content And Increased Digestibility, C Lynne Mcintyre, J M. Manners, J R. Wilson, H Way, D Sharp
Genetic Engineering Of Pasture Legume And Grasses For Reduced Lignin Content And Increased Digestibility, C Lynne Mcintyre, J M. Manners, J R. Wilson, H Way, D Sharp
IGC Proceedings (1977-2023)
Plants of tropical pastures have a higher lignin content than those of temperate pastures, which limits the digestibility and nutritive value of these forages. Ribozyme and antisense RNA technology is being investigated as a method of reducing lignin levels and increasing digestibility in the tropical forage Stylosanthes spp, and in the model system tobacco. Ribozymes to the tobacco anionic peroxidase mRNA have been designed and shown to be capable of cleaving this mRNA in vitro. Constructs for the expression of antisense and ribozyme RNA to reduce peroxidase gene expression have been prepared, Transgenic tobacco plants containing these constructs have been …
Advances In Genetic Transformation Of Plants, Thomas K. Hodges, Keerti S. Rathore, Jianying Peng
Advances In Genetic Transformation Of Plants, Thomas K. Hodges, Keerti S. Rathore, Jianying Peng
IGC Proceedings (1977-2023)
Many plant species, including both dicots and monocots, can now be genetically engineered with individual genes isolated from any source. Methods for delivery of foreign DNA into plant cells or protoplasts utilise Agrobacterium tumefaciens (and A. gazogenes), microinjection, polyethylene glycol, electroporation and particle guns. Advantages and disadvantages of each system are discussed. At present, all systems involve i11 vitra cell or tissue culture lo some extent, and this is the most difficult and variable aspect of plant genetic engineering. In addition, all systems suffer from random insertions of the foreign DNA into the plant genome. This requires Southern blot screening …
2024 Safety Belt Usage Survey In Kentucky, Erin Lammers-Staats, Derek Young, Kenneth R. Agent
2024 Safety Belt Usage Survey In Kentucky, Erin Lammers-Staats, Derek Young, Kenneth R. Agent
Kentucky Transportation Center Research Report
No abstract provided.
Forage News [2024-09], University Of Kentucky
Microfiltration Membrane Pore Functionalization With Primary And Quaternary Amines For Pfas Remediation: Capture, Regeneration, And Reuse, Sam Thompson, Angela Gutierrez, Jennifer Bukowski, Dibakar Bhattacharyya
Microfiltration Membrane Pore Functionalization With Primary And Quaternary Amines For Pfas Remediation: Capture, Regeneration, And Reuse, Sam Thompson, Angela Gutierrez, Jennifer Bukowski, Dibakar Bhattacharyya
UK CARES Faculty Publications
The widespread production and use of multi-fluorinated carbon-based substances for a variety of purposes has contributed to the contamination of the global water supply in recent decades. Conventional wastewater treatment can reduce contaminants to acceptable levels, but the concen- trated retentate stream is still a burden to the environment. A selective anion-exchange membrane capable of capture and controlled release could further concentrate necessary contaminants, mak- ing their eventual degradation or long-term storage easier. To this end, commercial microfiltration membranes were modified using pore functionalization to incorporate an anion-exchange moiety within the membrane matrix. This functionalization was performed with primary and …
Nitrate Removal By Floating Treatment Wetlands Under Aerated And Unaerated Conditions: Field And Laboratory Results, Jenna Mccoy, Matt Chaffee, Aaron Mittelstet, Tiffany L. Messer, Steve Comfort
Nitrate Removal By Floating Treatment Wetlands Under Aerated And Unaerated Conditions: Field And Laboratory Results, Jenna Mccoy, Matt Chaffee, Aaron Mittelstet, Tiffany L. Messer, Steve Comfort
Earth and Environmental Sciences Faculty Publications
Urban and storm water retention ponds eventually become eutrophic after years of receiving runoff water. In 2020, a novel biological and chemical treatment was initiated to remove accumulated nutrients from an urban retention pond that had severe algae and weed growth. Our approach installed two 6.1 m × 6.1 m floating treatment wetlands (FTWs) and two airlift pumps that contained slow-release lanthanum composites, which facilitated phosphate precipitation. Four years of treatment (2020–2023) resulted in median nitrate-N concentrations decreasing from 23 μg L−1 in 2020 to 1.3 μg L−1 in 2023, while PO4-P decreased from 42 μg L−1 to 19 μg …
Coal Ash Triggers An Elevated Temperature Landfill Development: Lessons From The Bristol Virginia Solid Waste Landfill Neighboring Community, Reagan Patton Witt, Marcelo I. Guzman
Coal Ash Triggers An Elevated Temperature Landfill Development: Lessons From The Bristol Virginia Solid Waste Landfill Neighboring Community, Reagan Patton Witt, Marcelo I. Guzman
UK CARES Faculty Publications
Landfills for disposing of solid waste are designed, located, managed, and monitored facili- ties expected to comply with government regulations to prevent contamination of the surrounding environment. After the average life expectancy of a typical landfill (30 to 50 years), a large investment in the construction, operation, final closure, and 30-year monitoring of a new site is needed. In this case study, we provide a holistic explanation of the unexpected development of elevated temperature landfills (ETLFs), such as that in the city of Bristol (United States) on the border of the states of Virginia and Tennessee, including the initial role …
Predicting The Association Of Metabolites With Both Pathway Categories And Individual Pathways, Erik D. Huckvale, Hunter Moseley
Predicting The Association Of Metabolites With Both Pathway Categories And Individual Pathways, Erik D. Huckvale, Hunter Moseley
Markey Cancer Center Faculty Publications
Metabolism is a network of chemical reactions that sustain cellular life. Parts of this metabolic network are defined as metabolic pathways containing specific biochemical reactions. Products and reactants of these reactions are called metabolites, which are associated with certain human-defined metabolic pathways. Metabolic knowledgebases, such as the Kyoto Encyclopedia of Gene and Genomes (KEGG) contain metabolites, reactions, and pathway annotations; however, such resources are incomplete due to current limits of metabolic knowledge. To fill in missing metabolite pathway annotations, past machine learning models showed some success at predicting the KEGG Level 2 pathway category involvement of metabolites based on their …