Digital Commons Network^™

Fiscal Year 2024 Fhwa-536 Report For The Kentucky Transportation Cabinet, Doug Kreis, Candice Wallace, Bryan Gibson, Sarah Mccormack

Kentucky Transportation Center Research Report

Every other year, the Federal Highway Administration (FHWA) requires that states submit a Local Highway Finance Report (FHWA-536) to the agency. This report summarizes data on local highway finances and is used by FHWA to evaluate relationships between and changes in revenues, expenditures and investment patterns, and financial trends. This report presents information submitted by Kentucky in its fiscal year (FY) 2024 FHWA-536. Total receipts from local, state, and federal sources used for road and street infrastructure equaled approximately $1.27 billion. Local sources of funding accounted for the largest share of total receipts (50%), followed by state government sources (41%), …

Kytc Digital Project Delivery Phase 1 Summary, Rachel Catchings

Kentucky Transportation Center Research Report

The Kentucky Transportation Cabinet (KYTC) launched its Digital Project Delivery (DPD) Initiative in September 2020 with the goal of expanding the use of digitally formatted plan and project information throughout the transportation asset life cycle, from project delivery through asset management. KYTC retained Kentucky Transportation Center (KTC) staff with expertise in construction and design to facilitate DPD implementation. This document summarizes DPD-related efforts undertaken by the Cabinet over the past five years. Key activities completed during this period include a survey of Kentucky Association of Highway Contractors members to document their perspectives on design file usage and preferences, coordinating multiple …

Kentucky Cdl Adjudication Pilot And Compliance Needs Study, Jeeyen Koo, Andrew Martin, Jennifer Walton

Kentucky Transportation Center Research Report

This report examines trends in how Kentucky District Courts have adjudicated charges related to commercial driver’s license (CDL) and commercial motor vehicles (CMVs). Using court data, researchers evaluated historical patterns in charge filing volumes as well as conviction, dismissal, amendment, and diversion rates. Between 2002 and 2024, conviction rates declined and dismissals increased. Convictions peaked in the mid-70% range in the early 2000s, but fell to the mid-50% range by 2024. Speeding and other serious traffic violations — many of which are advanceable offenses — were dismissed or amended at rates that could have substantively affected the integrity of CDL …

Human Atrial Skinned Muscle Fibers Exhibit Reduced Length-Dependent Activation But Show Faster Force Development Kinetics Than Ventricular Muscle, Alexandre Lewalle, Gregory Milburn, Jania Bell, Kenneth S. Campbell, Steven A. Niederer

Physiology Faculty Publications

In humans, the left atria (LA) and the left ventricle (LV) play distinct physiological roles and express sarcomeric proteins with chamber-specific patterns. Despite these important differences, most multi-chamber descriptions of the heart assume uniform myocardial properties. To facilitate a more accurate representation of cardiac function, we measured and compared the contractile properties of isolated skinned human LA and LV muscle fibers at 37 °C. Our experimental measurements included the length-dependent activation (LDA) of force in the isometric steady state, the force response to small quick length changes, and tension redevelopment dynamics. The LV measurements display more pronounced LDA behavior compared …

Driving Employee Engagement Across Sectors: Current Evidence And An Agenda For Future Research, Taha Hameduddin, Kerstin Alfes, Adrian Ritz

Public Policy and Administration Faculty Publications

Employee engagement has emerged as a critical employee attitude linked to employee motivation and organisational performance and has successfully embedded itself in governments around the world. Apart from a few exceptions, however, much of what we know about engagement does not attend to the institutional context of public institutions and whether private-sector theories and approaches to driving employee engagement work well in public sector organisations. To address this gap, we systematically review the evidence on antecedents of employee engagement, and determine whether and how sectoral differences may matter. We then discuss the findings and contextualise the debate surrounding the employee …

Consumer Perceptions Of Farmers Market Performance: A Comparative Analysis Across States And Age Groups, Azita Varziri, Timothy A. Woods, Shuoli Zhao

Agricultural Economics Faculty Publications

The USDA Agricultural Marketing Service has invested in direct-to-consumer initiatives to expand local food consumption and enhance farmers market opportunities. To evaluate the effectiveness of these efforts, this study employs a sample-selected ordered probit model to analyze consumer perceptions of farmers market performance across four states in the Southeast United States. Specifically, we examine differences in awareness and performance of product quality, diversity, and market infrastructure. Awareness and perceptions vary significantly by age, other demographics, and state. These insights provide market organizers and policymakers with data-driven strategies to tailor marketing efforts and improve engagement across diverse consumer segments.

Philsongs: A Study Of Campfire Music Performed At Scouting America’S Philmont Scout Ranch (2014 To 2021), Ellyn Rager

Theses and Dissertations--Music

This dissertation focuses on Philmont Scout Ranch, a national Scouting America high adventure base in New Mexico and the largest youth camp in the world, arguing that music at Philmont serves as a cultural force that fosters an intensive communal bond among staff and campers by blending participatory and presentational music-making practices, while producing and reinforcing memories of Philmont through interpretive performances that negotiate the place’s historical narratives. Using surveys, interviews, and Thomas Turino’s framework of participatory and presentational music-making to interpret the author’s 100 hours of field recordings, this study examines aspects of Philmont’s musical habits between 2014 and …

Investigation Of Genx Exposure To Pathways Associated With Colorectal Cancer Risk, Emily J. Ferguson

Theses and Dissertations--Toxicology and Cancer Biology

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants widely detected in drinking water and food sources, resulting in chronic human exposure. Among these compounds, hexafluoropropylene oxide dimer acid (HFPO-DA), commonly known as GenX, has been introduced as a short-chain replacement for legacy PFAS such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA). Although GenX is believed to be a safer alternative, emerging research suggests it can still affect human health.

Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer-related death in the United States, highlighting the need to better understand environmental …

Uncovering The Mechanism Of Reep2-Mediated Emt-Driven Membrane Trafficking In Lung Adenocarcinoma, Kevin Fulp

Theses and Dissertations--Toxicology and Cancer Biology

Membrane trafficking is frequently disrupted during cancer progression, and the underlying mechanisms remain largely unknown. Currently, no effective drugs target dysregulated membrane trafficking for cancer treatment. Recent evidence has demonstrated that epithelial-to-mesenchymal transition (EMT) in lung adenocarcinoma (LUAD) employs a membrane trafficking program to coordinate cancer cell invasion and immunosuppression. To further dissect the pro-tumorigenic membrane trafficking program, we initiated an in vivo CRISPRi screen to assess more than 2,000 membrane trafficking-related genes in a syngeneic mouse LUAD model. We identified REEP2, an endoplasmic reticulum (ER) shaping protein, as a novel regulator of EMT-driven membrane trafficking. High REEP2 expression is …

Reep2-Driven Pro-Metastatic Secretion Promotes Lung Cancer Progression, Oluwafunminiyi E. Obaleye

Theses and Dissertations--Toxicology and Cancer Biology

Membrane trafficking plays a critical role in cellular function and is frequently dysregulated in cancer to promote metastasis. In lung adenocarcinoma (LUAD), the epithelial-to-mesenchymal transition (EMT) activating transcription factor, ZEB1, drives a pro-metastatic membrane trafficking program; however, the underlying molecular mechanisms remain poorly understood. Using a CRISPR interference (CRISPRi) in vivo screen of 2,099 membrane trafficking regulators in a syngeneic mouse model of EMT-driven LUAD, we identified REEP2 — an endoplasmic reticulum (ER) shaping protein — as a critical regulator of tumor progression. REEP2 mRNA expression correlates with poor prognosis, EMT signatures, and an immunosuppressive tumor microenvironment in LUAD patients. …

Data-Driven Thresholds For Standardized Classification Of Severe Alzheimer’S Disease Neuropathology Using Digital Neuropathology, Ryan K. Shahidehpour, Allison M. Neltner, Mitchell A. Klusty, Cole Corbett, Angelique D. Gonzalez, David A. Gutman, David W. Fardo, Adam D. Bachstetter, Cody Bumgardner, Margaret E. Flanagan, Peter T. Nelson

Sanders-Brown Center on Aging Faculty Publications

Alzheimer's disease neuropathological changes (ADNC)—operationalized with semi-quantitative parameters—represent the consensus-based gold standard for diagnostic evaluation of disease severity. Although useful, ADNC diagnostic frameworks have limitations, particularly in advanced disease stages where pathological severity varies widely within a given diagnostic category. Further, some individuals lacking cognitive impairment are inappropriately categorized as having severe ADNC. In this study, quantitative pathology metrics and alternative tissue sampling schemes were integrated with data about premortem cognitive status, in order to derive clinically informed neuropathologic diagnostic thresholds. Specific goals of the current study were to generate data-driven, standardized diagnostic cut-points, with the most severe stages of …

Artificial Intelligence Methods For Circadian Rhythm Recovery And Disease Identification From High-Dimensional Omics Data, Aram Ansary Ogholbake

Theses and Dissertations--Computer Science

High-throughput transcriptomic and proteomic technologies have enabled opportunities for studying biological processes and disease mechanisms. However, extracting meaningful biological information from these high-dimensional datasets remains challenging due to limited sample sizes, biological heterogeneity, measurement noise, and the absence of biological annotations. In particular, many molecular datasets lack temporal information required for circadian analysis, making the study of circadian rhythms difficult. Moreover, disease diagnosis and biomarker discovery from transcriptomic data often rely on complex machine learning models whose predictions are difficult to interpret and may not generalize well across independent datasets and experimental platforms. These limitations motivate the development of artificial …

Dynamical Phases Of Higher Dimensional Floquet Cfts, Diptarka Das, Sumit R. Das, Arnab Kundu, Krishnendu Sengupta

Physics and Astronomy Faculty Publications

This paper investigates the dynamical phases of Floquet Conformal Field Theories (CFTs) in space-time dimensions greater than two. Building upon our previous work which introduced quaternionic representations for studying Floquet dynamics in higher-dimensional CFTs, we now explore more general square pulse drive protocols that go beyond a single SU(1,1) subgroup. We demonstrate that, for multi-step drive protocols, the system exhibits distinct dynamical phases characterized by the nature of the eigenvalues of the quaternionic matrix representing time evolution in a single cycle, leading to different stroboscopic responses. Our analysis establishes a fundamental geometric interpretation where these dynamical phases directly correspond to …

Aster Remote Sensing Satellite Imagery For Regional Mineral Mapping In The Mcmurdo Dry Valleys, South Victoria Land, Antarctica, Khurram Riaz, Amin Beiranvand Pour, Jabar Habashi, Aidy M. Muslim, Iman Masoumi, Ali Moradi Afrapoli, Mazlan Hashim, Kamyar Mehranzamir, Farshid Sattari

Mining Engineering Faculty Publications

The McMurdo Dry Valleys (DVs) of South Victoria Land, Antarctica, constitute the largest ice-free region on the continent and one of Earth’s most Mars-analog environments. Their hyper-arid polar desert conditions offer a unique setting for investigating surface weathering and mineralogical processes under extreme climates. This study presents the first regional-scale mapping of alteration and crystalline weathering minerals across the McMurdo DVs. It uses Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) multispectral data; visible and near-infrared (VNIR) and shortwave infrared (SWIR) bands were analyzed through a Spectral Hourglass Workflow, endmember extraction, and spectral unmixing with Matched Filtering (MF) and Constrained …

Making Inquiry Accessible: Inquiry-Based Design And Instruction For English Learners In Secondary Social Studies Classrooms, Meghan T. Hawkins

Theses and Dissertations--Education Sciences

This dissertation explores inquiry-based instruction for English Learners (ELs) in secondary social studies classes. The first article explored the existing literature in the field. The second article considered instructional design choices that could increase learning outcomes in an inquiry designed for ELs, implemented in a culturally and linguistically responsive classroom. Finally, the third article is an exploratory case study that examined how a secondary high school social studies teacher and ESL co-teacher designed and implemented inquiry-based instruction in a co-taught ESL class. The research questions included: 1. How do teachers build trust in a culturally and linguistically responsive social studies …

Fiscal Decentralization, Foreign Capital, And Economic Development In Sub-Saharan Africa, Kwadwo D. Frempong

Theses and Dissertations--Public Policy and Administration

Economic development in Sub-Saharan Africa has been shaped by two transformative policy shifts: widespread fiscal decentralization reforms transferring revenue and expenditure authority to subnational governments, and the pursuit of foreign direct investment to supplement domestic capital. Despite the breadth of these reforms, their effectiveness in promoting sustainable economic development remains empirically contested. This dissertation examines three interconnected questions about fiscal governance and capital flows in Sub-Saharan Africa: what determines the extent to which governments decentralize fiscal authority; how county fiscal composition and revenue autonomy shape subnational economic performance; and how foreign direct investment interacts with domestic investment and growth.

The …

Nutrient-Driven Transcription Factor-Dna Interactions And Their Signaling Mechanisms In Metabolic Disease, Evelyn A. Bates

Theses and Dissertations--Nutritional Sciences

Metabolic homeostasis is maintained through tightly coordinated signaling networks that integrate diverse physiological inputs. Central to this regulation are transcription factors, which sense nutrient, hormonal, and vitamin-derived signals and translate them into coordinated gene expression programs. Transcription factor activity is governed by DNA binding, recruitment of coregulatory proteins, and interactions with specific response elements in gene promoters, which allows them to selectively modulate diverse metabolic pathways. Owing to their multifactorial and tunable nature, transcription factors have emerged as promising targets for the treatment and diagnosis of metabolic diseases, including metabolic dysfunction-associated steatotic liver disease (MASLD). This dissertation explores the molecular …

Do Magnesium Ions Have Similar Effects As Calcium Ions On Resting Membrane Potential?, Anthony Hana, Youngwoo Kim, Joy Bidros, Katie Neglia, Robin L. Cooper

Biology Faculty Publications

Maintaining a membrane electrical potential of biological cells is a dynamic process, as some cells have a continually changing potential, like pacemaker cells, while other cells may function with large or small changes in the membrane potential. Additionally, some cells may change their electrical potential when stimulated or inhibited by electrical signals, chemical compounds, or both—either simultaneously or episodically. The persistent leak of K⁺ through two-pore-domain potassium channels (K2P) and of Na⁺ through Na⁺ leak channels (NALCNs) and the action of pumps and exchangers are primarily responsible for maintaining a resting potential. Ca²⁺ ions are known …

Expressing Experiences Of Being Gender Non-Conforming In The “Ladies” Restroom Through Autoethnography-Based Research Poetics, Ellen D.B. Riggle

Gender and Women's Studies Faculty Publications

Three research poems are created as an autoethnographic response to feedback on a research article on the author’s experiences as a gender non-conforming person in women’s public restrooms. The feedback loop includes the sharing of lived experiences by others and theoretical (why?) discussions in the context of the gendered policing and politicalization of women’s restrooms. The first found poem includes words, phrases, and descriptions of images used to label spaces designated as women’s restrooms. The second prose poem recounts the author's experiences through a reframing of risk to women’s health, understanding the cultural context of male entitlement and White supremacy, …

“We Do Things A Little Different Exactly As You'd Expect Here...": Egocentric Network Structures As Predictors Of Organizational Culture Type, Ray Celeste S. Tanner

Theses and Dissertations--Communication

This dissertation examines organizational culture as an outcome of communication structures by integrating the Competing Values Framework (CVF) with egocentric network analysis. Although CVF is one of the most widely used frameworks for diagnosing organizational culture and predicting organizational effectiveness, prior research has overwhelmingly treated culture as an independent variable. Responding to calls for greater attention to the antecedents of culture, this study reconceptualizes organizational culture as a dependent variable and investigates how individuals’ perceived communication networks predict perceptions of CVF culture types. Using egocentric network data collected from employees across a diverse range of organizations and industries, this study …

Conflict Management In Heterosexual Romantic Relationships: A Cognitive Dissonance Perspective, Benjamin Grissom

Theses and Dissertations--Communication

This paper examines how cognitive dissonance corresponds with conflict management strategies in heterosexual romantic relationships from the perspective of romantic partners. The paper synthesizes current findings on how conflicting beliefs and attitudes impact partners' approaches to handling disagreements. Patterns are identified in how cognitive dissonance co-occurs with competition, avoidance, accommodation, compromise, and collaboration. Findings suggest that the discomfort arising from holding conflicting cognitions corresponds to their conflict management approaches depending on the degree of discomfort. Additionally, relationship length is examined as a moderator of the connection between cognitive dissonance and conflict management. Understanding these perceptions can provide insights into enhancing …

The Role Of Fandom On Perceived Racial Stereotypes Presented By The Media’S Coverage Of Sport And Crime, Christopher F. Clements

Theses and Dissertations--Communication

This dissertation examines the intersection of sport, media, and race, focusing on the ways in which media portrayals of athletes involved in criminal activity relate to the reinforcement of racial stereotypes. Utilizing social identity theory (SIT), this dissertation employs three video clips of minority athletes at the time of their arrests to examine how media representations of minority athletes contribute to the reinforcement of viewers’ racial stereotypes and to investigate the impact of participants’ pre-existing racial stereotypes upon their perceptions of media representations of Black athletes involved in criminal activity. This dissertation utilizes focus groups to examine how fandom, as …

Students As Information Responders – Extending Our Understanding Of Students At A Pwi, Anyiah S. Chambers

Theses and Dissertations--Communication

As school shootings continue to rise across the United States, understanding how students respond to and share information during crises has become a critical concern for higher education institutions. While prior research has examined the role of students as first information responders (FIRs) during emergencies, few studies have investigated how these processes unfold among Black and non-Black students at predominantly white institutions (PWIs). This mixed methods study is a replication and extension of Omilion-Hodges and Edwards (2021), examining how undergraduate Black and non-Black students at PWIs evaluate, construct, and disseminate crisis-related messages, particularly during active-shooter events. Grounded in channel specification …

Enabling Communication Resiliency In The Connected Car Environment, Antonio Guerrero-Ibáñez, Juan Contreras-Castillo, Sherali Zeadally, Een-Kee Hong

Information Science Faculty Publications

Connectivity has become integral to various application domains, with the automotive sector as a prime example. Advances in electronics, computing, and telecommunications have driven the evolution of the connected car ecosystem, transforming it into a data-rich environment that enhances road safety, efficiency, and overall mobility. However, the success of this ecosystem depends on seamless, reliable, and resilient communications. We identify key challenges that may affect communications in the connected car environment and discuss solutions that enhance resiliency and robustness. Finally, we propose a multi-layered network architecture that will enhance communication resilience in the connected car ecosystem.

Legislative Debate-Attributed Suicidality Among Lgbtq+ Adults: The Buffering Effect Of Community Belongingness, Keith J. Watts, Shawndaya S. Thrasher, Laneshia Conner, Nicole Campbell, Louis G. Baser, Dekeitra Griffin, Sydney Howard, Missy Spears, Justin X. Moore

Social Work Faculty Publications

Background: In recent years, the sociopolitical landscape in the United States has shifted due to an increase in state-level legislation regarding LGBTQ+ rights, a trend that has been particularly pronounced in the Commonwealth of Kentucky. While the mental health impacts of enacted laws are increasingly documented, a critical gap remains in understanding the psychological toll of the legislative debates themselves—the prolonged periods of public discourse surrounding the restriction of rights.

Methods: Utilizing data from the 2025 Queer Kentucky Survey (N = 817), this exploratory study examined the association between LGBTQ+ community belongingness and acute suicidality attributed specifically to anti-LGBTQ+ legislative …

Limitations Of Reproductive Manipulation By Bacterial Endosymbionts In A Spider Host, Jordyn D. Proctor

Theses and Dissertations--Entomology

Maternally inherited bacterial endosymbionts are common in arthropods. Many of these bacteria manipulate host reproduction to favor the production of infected females, thereby increasing bacterial prevalence in the host population, even if cost is incurred to the host. However, there are also many factors that may inhibit symbionts’ ability to spread in host populations, including environmental constraints, symbiont-imposed costs on the host, interactions with co-infecting bacteria, or host biology. I explored two aspects of symbiont biology within a spider host, Mermessus fradeorum (Linyphiidae), which has varying combinations of up to five different bacterial endosymbionts in local populations: Rickettsiella, Tisiphia …

“Oh, You’Ve Come To Visit The Yard?”: Phenotypic Capital, Intragroup Marginalization, And The Gated Sanctuary In Black Lgbtq+ Communities, Keith J. Watts, Shawndaya S. Thrasher, Nicole Campbell, Laneshia Conner, Julian K. Glover, Janet K. Otachi, Dekeitra Griffin

Social Work Faculty Publications

Identity-based communities that share common characteristics, beliefs, and experiences (e.g., Black LGBTQ+ communities) have historically been conceptualized as protective bubbles that buffer Black LGBTQ+ individuals against the deleterious effects of systemic racism and cisheterosexism. However, this monolithic narrative often masks the internal power dynamics that divide belonging. This study explores the exclusionary dynamics embedded within these safe spaces, examining how internal hierarchies of skin tone, socioeconomic status, and gender performance function as proximal stressors. Guided by a critical constructivist paradigm, this study utilized Reflexive Thematic Analysis to analyze open-ended survey responses from 74 Black LGBTQ+ adults. Data were drawn from …

Excess Nitric Oxide Alters Cellular Ph To Restrict Salicylic Acid Movement And Systemic Immunity, Fan Xia, Huazhen Liu, Keshun Yu, Xinyu Yuan, Aardra Kachroo, Pradeep Kachroo

Plant Pathology Faculty Publications

Plants carrying a mutation in S-nitrosoglutathione reductase 1 (GSNOR1) accumulate high nitric oxide (NO) and exhibit impaired immunity characterized by reduced pathogen-responsive salicylic acid (SA) accumulation and failure to activate normal SA signaling. We show that this reduced SA responsiveness in gsnor1 plants arises from impaired vascular-associated movement of SA, thereby compromising systemic acquired resistance (SAR). Elevated NO perturbs cellular pH homeostasis, acidifying the apoplast and alkalinizing the cytosol, which likely interferes with phloem-associated SA movement and renders gsnor1 plants unresponsive to foliar SA. In contrast, SA supplied via root drench restores SA signaling and SAR in gsnor1, …

Endocranial Morphological Affinities Of The Early Holocene Individuals From Lagoa Santa And Implications For The Peopling Of The Americas, María Clara López-Sosa, Hugo Reyes-Centeno, Lumila Paula Menéndez, Rodrigo Elias Oliveira, Claudio Campi De Castro, André Strauss

Anthropology Faculty Publications

The ectocranial morphology of early Holocene humans from Lagoa Santa, Brazil has been described as exhibiting a ‘Paleoamerican’ form with affinities to African and Australasian individuals, in contrast to past and present Native Americans, who predominantly exhibit ‘Amerindian’ form. While this interpretation remains disputed, its led to the ‘Two Main Biological Components Model’, which proposes separate dispersals from Asia into the Americas. This study aims to assess whether the endocranial morphology of Lagoa Santa individuals similarly reflects these affinities. For this study, the overall endocranial morphology, as well as the temporal bones of the crania of twenty individuals from Lagoa …

Zero Tolerance Or Strong Cultural Diversity: The Hard Case Of Female Genital Surgery, James M. Donovan, Christiane Canant

Law Faculty Scholarly Articles

This article applies a thesis favoring strong cultural diversity to defend a subject-centered policy regarding female genital surgeries (FGS). That idea posits that cultural variation holds an intrinsic value that should be presumptively respected when setting policy and creating law. Correlatively, cultural homogenization, especially by force, should be resisted. 

Taking as a starting point the recent celebration of the United Nation’s Day of Zero-Tolerance for Female Genital Mutilation, the paper reviews the context of FGS practices in various societies and critiques the inconsistencies of U.N. arguments to advance its goal of total elimination by 2030. Especially problematic for the U.N. …