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Articles 841 - 870 of 18111
Full-Text Articles in Entire DC Network
Introducing Neuro Sscial Work: A Brief Reflection On Neuroscience And The Profession, Priscila Llamosa
Introducing Neuro Sscial Work: A Brief Reflection On Neuroscience And The Profession, Priscila Llamosa
Social Work Faculty Publications
This reflection introduces and contextualizes the term Neuro Social Work, which I coin to name a specialized practice area at the intersection of social work, neuroscience, and neurodiversity. Drawing on my experience as a social work educator and practitioner, I discuss social work’s uneasy relationship with neuroscience, marked both by the opportunity to deepen our understanding of trauma, development, and healing, and by the risks of using brain‑based evidence to individualize structural harms or justify surveillance of marginalized communities. I outline, in broad strokes, what distinguishes Neuro Social Work from general neuroscience‑informed practice. The note is intended as a concept …
The Next Generation, Jeremiah Chin
Scotus's Summer Of 2022: Obfuscation Of And Disdain For Rationality And The Traditional Personal Liberties Framework, Roy G. Spece Jr.
Scotus's Summer Of 2022: Obfuscation Of And Disdain For Rationality And The Traditional Personal Liberties Framework, Roy G. Spece Jr.
Kentucky Law Journal
No abstract provided.
An Annotated Chromosome-Level Genome For The Red-Fronted Brown Lemur (Eulemur Rufifrons) Sheds Light On Brown Lemur Evolution, Kathryn M. Everson, Andrew N. Black, Mariah E. Donohue, David W. Weisrock
An Annotated Chromosome-Level Genome For The Red-Fronted Brown Lemur (Eulemur Rufifrons) Sheds Light On Brown Lemur Evolution, Kathryn M. Everson, Andrew N. Black, Mariah E. Donohue, David W. Weisrock
Biology Faculty Publications
The red-fronted brown lemur (Eulemur rufifrons) is an important species to the function of Madagascar’s ecosystems, contributing to critical ecological processes such as seed dispersal. Given its ecological, as well as cultural, importance, genomic resources for E. rufifrons are valuable for understanding evolutionary history and informing conservation strategies. In this study, we present an annotated chromosome-level genome assembly for E. rufifrons, generated using PacBio HiFi long reads and Hi-C proximity ligation data, and demonstrate its utility for understanding patterns of divergence among members of the genus Eulemur. The chromosome-level genome size is 2.41 Gb, and it exhibits high-quality metrics including …
Apoe-Targeted Therapeutics For Alzheimer’S Disease, Hussein N. Yassine, Cristelle Hugo, Bernadette O’Donovan, Isaiah O. Stephens, Lance A. Johnson, Gregory Cole, Julia Tcw, Jan Johansson, Kassandra Kisler, Ornit Chiba-Falek
Apoe-Targeted Therapeutics For Alzheimer’S Disease, Hussein N. Yassine, Cristelle Hugo, Bernadette O’Donovan, Isaiah O. Stephens, Lance A. Johnson, Gregory Cole, Julia Tcw, Jan Johansson, Kassandra Kisler, Ornit Chiba-Falek
Physiology Faculty Publications
Apolipoprotein E (APOE) is the major lipid transport protein in the brain. Produced primarily by astrocytes and microglia, it delivers cholesterol and other lipids for membrane repair, synaptic maintenance, and immune regulation. Through interactions with specific lipid receptors, APOE maintains neuronal and vascular health. The APOE ε4 allele (APOE4), carried by approximately one-quarter of the population, has an altered protein conformation, which reduces lipid transport efficiency and modifies receptor binding. These changes disrupt lipid homeostasis, increase risk of chronic unresolved neuroinflammation and vascular inflammation, and cause breakdown of the blood–brain barrier (BBB), thus increasing neuronal vulnerability to disease pathology and …
Equality Can Stick With Bostock: A Call To Expand The Equal Protection Clause To Include Discrimination Against Transgender People's Bathroom Usage, Jackson B. Hurst-Sanders
Equality Can Stick With Bostock: A Call To Expand The Equal Protection Clause To Include Discrimination Against Transgender People's Bathroom Usage, Jackson B. Hurst-Sanders
Kentucky Law Journal
No abstract provided.
These Brutal Indignities: The Case For Crimes Against Humanity In Black America, Tiffany D. Atkins
These Brutal Indignities: The Case For Crimes Against Humanity In Black America, Tiffany D. Atkins
Kentucky Law Journal
No abstract provided.
Inequality By Unnatural Selection: The Impact Of Tax Code Bias On The Racial Wealth Gap, Phyllis C. Tate
Inequality By Unnatural Selection: The Impact Of Tax Code Bias On The Racial Wealth Gap, Phyllis C. Tate
Kentucky Law Journal
No abstract provided.
Prenatal Cocaine Exposure, Perinatal Risks, And Mediators To Preadolescent Attention Deficit Hyperactivity Disorder (Adhd), Thitinart Sithisarn, Carla M. Bann, Barry Lester, Seetha Shankaran, Toni Whitaker, Rosemary D. Higgins, Henrietta Bada
Prenatal Cocaine Exposure, Perinatal Risks, And Mediators To Preadolescent Attention Deficit Hyperactivity Disorder (Adhd), Thitinart Sithisarn, Carla M. Bann, Barry Lester, Seetha Shankaran, Toni Whitaker, Rosemary D. Higgins, Henrietta Bada
Epidemiology and Environmental Health Faculty Publications
Highlights: What are the main findings? Prenatal cocaine exposure increases the risk of ADHD in preadolescence, with effects largely mediated through attention problems and impulsivity at 4–5 years of age. Male sex is an independent risk factor with a direct path to the ADHD diagnosis. What is the implication of the main finding? Screening for behavioral problems before 4 years of age in prenatal cocaine exposure would make possible early intervention to mitigate later diagnosis or severity of ADHD. Attention-deficit/hyperactivity disorder (ADHD) is the most common behavioral problem in children. Multiple risk factors, including prenatal substance exposure, have been associated …
The Neighborhoods Study, Grace C. George, Sarah A. Keller, Erin Abner, Sara Adar, Michael L. Alosco, Liana G. Apostolova, Kelly Bakulski, Lisa L. Barnes, James R. Bateman, Stuart Batterman, Thomas G. Beach, Barbara B. Bendlin, David A. Bennett, Tobey J. Betthauser, James Brewer, William Buckingham, Carmen I. Carrión, Joshua Chodosh, Suzanne Craft, Raina Croff, Anthony Fabio, Sarah Tomaszewski Farias, Eva L. Feldman, Felicia Goldstein, Stephen A. Goutman, Gina Green-Harris, Victor Henderson, Thomas K. Karikari
The Neighborhoods Study, Grace C. George, Sarah A. Keller, Erin Abner, Sara Adar, Michael L. Alosco, Liana G. Apostolova, Kelly Bakulski, Lisa L. Barnes, James R. Bateman, Stuart Batterman, Thomas G. Beach, Barbara B. Bendlin, David A. Bennett, Tobey J. Betthauser, James Brewer, William Buckingham, Carmen I. Carrión, Joshua Chodosh, Suzanne Craft, Raina Croff, Anthony Fabio, Sarah Tomaszewski Farias, Eva L. Feldman, Felicia Goldstein, Stephen A. Goutman, Gina Green-Harris, Victor Henderson, Thomas K. Karikari
Epidemiology and Environmental Health Faculty Publications
INTRODUCTION: The Neighborhoods Study (TNS) is a novel investigation of adverse social exposome and brain health leveraging 22 Alzheimer's Disease Research Centers (ADRCs). TNS aims to understand if the adverse social exposures increase Alzheimer's disease and related dementias (ADRD) risk. METHODS: TNS uses innovative methods to determine lifetime addresses of living (n = ≈ 3116) and brain bank cohorts (n = ≈ 8637). Addresses are linked to time-concordant adverse social exposome using the Area Deprivation Index (ADI) and summarized over time. Brain health measures are provided by the National Alzheimer's Coordinating Center. RESULTS: We highlight a general overview and methodology …
Frequency Dependence Favours Social Plasticity And Facilitates Socio-Eco-Evolutionary Feedback In Fluctuating Environments, Jordan S. Martin, David F. Westneat, Alastair J. Wilson, Niels J. Dingemanse, Yimen G. Araya-Ajoy
Frequency Dependence Favours Social Plasticity And Facilitates Socio-Eco-Evolutionary Feedback In Fluctuating Environments, Jordan S. Martin, David F. Westneat, Alastair J. Wilson, Niels J. Dingemanse, Yimen G. Araya-Ajoy
Biology Faculty Publications
Increasing attention is being devoted to the study of phenotypic plasticity in social environments. However, much remains unknown about the selection pressures driving the evolution of social plasticity, as well as the pathways by which social plasticity may facilitate or constrain feedback between ecological and evolutionary dynamics. Here, we explore these questions using quantitative genetic models, providing general results regarding the causes of selection on social reaction norms, as well as their consequences for adaptive microevolution in fluctuating environments. We model the fitness effects of character states expressed across spatially heterogeneous microhabitats, with variation in the degree to which trait …
The Population History Of Central Europe In The Early Bronze Age (2200/2100–1600/1500 Bc) - A Craniometric Approach, Tamás Szeniczey, Eszter Melis, Július Jakab, Jozef Bátora, István Major, Mihály Molnár, Anikó Horváth, László Palcsu, Anett Gémes, Katalin Gyenesei, Hugo Reyes-Centeno, Viktória Kiss, Tamás Hajdu
The Population History Of Central Europe In The Early Bronze Age (2200/2100–1600/1500 Bc) - A Craniometric Approach, Tamás Szeniczey, Eszter Melis, Július Jakab, Jozef Bátora, István Major, Mihály Molnár, Anikó Horváth, László Palcsu, Anett Gémes, Katalin Gyenesei, Hugo Reyes-Centeno, Viktória Kiss, Tamás Hajdu
Anthropology Faculty Publications
During the Late Neolithic and Early Bronze Age, migrations and the advent of working bronze alloy materials triggered profound cultural, social, and economic shifts across Central Europe. As a result of this processes, many communities with distinct archaeological and cultural characteristics emerged during the Central European Early Bronze Age (between circa 2200/2100 and 1600/1500 BC) in Central Europe, and with the Middle Bronze Age of the Carpathian Basin (between 2000/1900 and 1500/1450 BC). This study examines the biological relationships among these populations through biodistance analyses, aiming to clarify connections between cultural and biological affinities within the emerging heterogeneous communities. Craniometric …
Knockout Of Perilipin-2 In Microglia Alters Lipid Droplet Accumulation And Response To Alzheimer’S Disease Stimuli, Isaiah O. Stephens, Lance A. Johnson
Knockout Of Perilipin-2 In Microglia Alters Lipid Droplet Accumulation And Response To Alzheimer’S Disease Stimuli, Isaiah O. Stephens, Lance A. Johnson
Physiology Faculty Publications
Highlights: What are the main findings? Knockout of Plin2 in microglia reduces lipid droplet burden, while enhancing phagocytic clearance capacity. Transcriptomic, bioenergetic, and lipidomic analyses reveal that loss of Plin2 reprograms microglial metabolism toward reduced TAG storage and improved mitochondrial resilience. What are the implications of the main findings? Plin2 serves as a key regulator of microglial lipid droplet stability, metabolic flexibility, and immune function under Alzheimer’s-relevant stressors. Targeting Plin2 may represent a therapeutic strategy to alleviate lipid droplet-driven dysfunction and restore microglial performance in aging and neurodegeneration. Lipid droplets (LDs) are emerging as key regulators of metabolism and inflammation, …
Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao
Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao
Animal and Food Sciences Faculty Publications
The gonad is one of the major byproducts of sea cucumber. Four novel antioxidant peptides (NPWGQ, PGHPF, VPYPR and ATGPQGPAGQRGPAGPTGPTGPAG) were isolated and identified from sea cucumber gonad proteins through enzymatic hydrolysis and antioxidant activity-guided fractionation, bioinformatics approaches and in silico screening. These peptides demonstrated great free radical (2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS))-scavenging activity and notable superoxide dismutase (SOD)-activation capacity. Molecular docking and molecular dynamics simulation data suggested that these peptides could form strong binding with SOD through hydrogen bonding, electrostatic interactions, and hydrophobic interactions. Among these peptides, NPWGQ displayed the most potent antioxidant and SOD-activating effects. Through searching …
Unworthy Heirs: The Slayer Rule And Beyond, Mary Elizabeth Morey
Unworthy Heirs: The Slayer Rule And Beyond, Mary Elizabeth Morey
Kentucky Law Journal
No abstract provided.
Balancing Broad Disclosure And Candid Consideration: Third-Party Consultants And Intra-Agency Exemptions Under The Freedom Of Information Act, Zac Losey
Kentucky Law Journal
No abstract provided.
Genetic Engineering For Pastures, W J. Peacock
Genetic Engineering For Pastures, W J. Peacock
IGC Proceedings (1977-2023)
The first genetically engineered food products from horticultural production systems are now entering the mnrke< and field trials of genetically engineered crop species are well advanced. We cnn expect that a range of crop cultivars, in which gene
Grassland For Sustainable Ecosystems, Malcolm Hadley
Grassland For Sustainable Ecosystems, Malcolm Hadley
IGC Proceedings (1977-2023)
Grasslnnds present many advantages for examining issues related to sustainability. Grasslands include planted pastures as well as a variety of natural rangelands in situations ranging from semi-arid to subhumid. Diversity is also reflected in the spectrum of grassland users and uses, for example, nomadic pastoralism, extensive ranches, intensive pastures, wildlife tourism, game hunting. And in terms of sustainability of resource management, grasslands encompass a wide range of contrasting situations and conflicts in resource use. Heavy grazing pressure associated with increasing human populations in certain tropical savannas, the implications of rural depopulation to traditional pasture management in alpine regions, and the …
Grasslands For Our World, F Riveros
Grasslands For Our World, F Riveros
IGC Proceedings (1977-2023)
The present-day role of grasslands and fodder is reviewed with respect agriculture, animal production and environmental concerns. The world's grazing lands are a finite resource and, overall, arc being badly managed; in most developing countries action is required now, before it is too late. They will continue to be a major source of animal feed for the foreseeable future; encroachment from cropping will continue locally but, for much of what is now natural pasture, exploitation by the grazing animal .will remain the major means of obtaining an economic return; the task of grassland professionals is to assist the managers of …
Human Impact On Terrestrial Ecosystems - What We Know And What We Are Doing About It, H A. Mooney
Human Impact On Terrestrial Ecosystems - What We Know And What We Are Doing About It, H A. Mooney
IGC Proceedings (1977-2023)
At present the impact of humankind on the Earth System is substantial and will become greater as we continue to add over 80 million people to the global population each year. Collectively the human species utilises over a third of the total fresh water that is available, as well as an equivalent amount of the total terrestrial productivity. Possil energy is being consumed at a prodigious rate and fuels, among other things, over a half a billion vehicles. To support the large human population the Earth has been greatly reconfigured with much of the land utilised for grazing and agriculture. …
Science And Information For Our Grasslands, G A. Nores, R R. Vera
Science And Information For Our Grasslands, G A. Nores, R R. Vera
IGC Proceedings (1977-2023)
This paper favours a view of grasslands, and agricultural research in general, that extends well beyond the limits of the scientific community and promotes the active involvement of scientists in current societal debates from a scientific perspective. It is argued that in developed countries environmental concerns rather than production growth will tend to dominate future social debate. In developing countries there is a need to balance agricultural growth with responsible management of natural resources. Needs for new technology go beyond improving biophysical efficiency, and involve economic and social efficiency objectives. The relevance of grassland research is assessed in terms of …
Vegetation Dynamics In Grazed Systems: A Hierarchical Perspective, D D. Briske
Vegetation Dynamics In Grazed Systems: A Hierarchical Perspective, D D. Briske
IGC Proceedings (1977-2023)
Grassland vegetation consists of a series of hierarchical levels including the tiller, plant, population and community which collectively influence the productivity and stability of grazed systems. These hierarchical levels may respond uniformly to influence vegetation dynamics, but frequently additional complexity is encountered by the occurrence of opposing responses between or among hierarchical levels. Consequently, it is important to consider responses at several hierarchical levels to achieve an accurate interpretation of vegetation dynamics to grazing within the community. The significance of a hierarchical perspective to vegetation management is illustrated with examples from bunchgrass dominated rangelands at the level of the individual …
Forage Conservation And Physico-Chemical Conversion, E Zimmer
Forage Conservation And Physico-Chemical Conversion, E Zimmer
IGC Proceedings (1977-2023)
The factors on which the digestibility of organic matter (dMO) of forages depend are now well-known. In temperate forages, this digestibility depends mainly on the growth stage, the rank of the growth-cycle, and the botanical species. It is constantly decreasing with advancing age, especially during the first growth-cycle. In aftermath growth-cycles, high temperatures accelerate the decrease of digestibility with age. Tropical forages follow the same laws, but tropical grasses are less digestible than cool-season grasses, especially at young stages and in warm weather. This is partly due to the fact that high temperatures increase cell-wall contents and lignification, and also …
The Feeding Value Of Forages, C Demarquilly
The Feeding Value Of Forages, C Demarquilly
IGC Proceedings (1977-2023)
The lower productivity of legume based swards and their instability of yield from year to year compared with nitrogen fertilised grass swards continues to be a major constraint on the integration of leguminous nitrogen fixing species into present-day farming systems. Most legume systems have a high biological nitrogen fixation (BNF) potential which is rarely attained in the· field due to limiting environmental or management factors. Enhancement of BNF through manipulation of the Rhizobium and plant components of the symbiosis must be viewed as a long-term objective. Optimisation of nitrogen fixation in the short-term may best be achieved through optimisation of …
Nitrogen Fixation, Cycling, And Utilization, P M. Murphy, M T. Sherwood
Nitrogen Fixation, Cycling, And Utilization, P M. Murphy, M T. Sherwood
IGC Proceedings (1977-2023)
The lower productivity of legume based swards and their instability of yield from year to year compared with nitrogen fertilised grass swards continues to be a major constraint on the integration of leguminous nitrogen fixing species into present-day farming systems. Most legume systems have a high biological nitrogen fixation (BNF) potential which is rarely attained in the· field due to limiting environmental or management factors. Enhancement of BNF through manipulation of the Rhizobium and plant components of the symbiosis must be viewed as a long-term objective. Optimisation of nitrogen fixation in the short-term may best be achieved through optimisation of …
La Prairie Dans Ses Usages Multiples: Conservation Des Sols, Protection De L'Environnement, Etc., M Skouri, J Poissonet
La Prairie Dans Ses Usages Multiples: Conservation Des Sols, Protection De L'Environnement, Etc., M Skouri, J Poissonet
IGC Proceedings (1977-2023)
Les terres :i paturage couvrent une partie importante de la planete et presentent une extreme diversite de situations en fonction des conditions ecologiques et des facteurs socio-economiques et culturels qui s'exercent sur ces espaces. Ces facteurs ont engendre des transformations du milieu nature] permettant d'intensifier, et :i ]'extreme, de contr61er la production vegetale de ces ecosystemes. Si le role premier de ces formations herbacees a ete d'alimenter Jes herbivores afin que l'homme en obtienne une production (viande, lait, peaux, etc.), Jes autres fonctions de ces espaces ont une importance que !'on ne peut se permettre de negliger, que ce soit …
Quickening Snow Melting In Early Spring With Black Powder In Snowy District, A Imai
Quickening Snow Melting In Early Spring With Black Powder In Snowy District, A Imai
IGC Proceedings (1977-2023)
Experiments were conducted during 1977-1980 to quiken snow melting in early spring with three kinds of black powders at 450 m a.s.l.,Tsunan-machi, Niigata Prefecture. Snow melting materials involved blast furnace slag, di-amido lime and calcium silicate and their effects on snow melting were compared with each other at various application rates on snow surface in late March every year. Snow melting was earlier with 600 kg/ha di-amido lime resulting from lower albedo of 25 % and it could quicken the snow-off by 10-13 days as compared to the control plot. This early snow melting induced the higher soil temperature and …
Effect Of Fertilization In Autumn Or After Wintering On Dallisgrass Production In The Following Season, T Kobayashi
Effect Of Fertilization In Autumn Or After Wintering On Dallisgrass Production In The Following Season, T Kobayashi
IGC Proceedings (1977-2023)
To improve dallisgrass (Paspalum dilatatum Poir.) pasture productivity, the effects of autumn or spring topdressing in a field experiment and autumn nitrogen (N) application levels in a pot experiment on the regrowth and carbohydrate accumulation until winter and on the early summer production were studied. Dallisgrass pasture was topdressed in either autumn (late September) or spring (early March) at 0.5 kg/a each of N, phosphate (P2O5), and potash (K20), after the final cutting in late September 1978. Plants in pots were topdressed at the rates of 0.5, 1, 2, and 4 kg N/a, just after cutting in early October …
Selenium Pellets Administration In Cows Grazing Continuously On Low Selenium Grassland In Japan, J Jachja, N Ishida, R Kawashima, K Otsuki, K Otsuki, M Kawano, F Hosoyamada
Selenium Pellets Administration In Cows Grazing Continuously On Low Selenium Grassland In Japan, J Jachja, N Ishida, R Kawashima, K Otsuki, K Otsuki, M Kawano, F Hosoyamada
IGC Proceedings (1977-2023)
The effectof selenium (Se) supplementation in cows upon the growth of their newborn calves under the conditions of continuous grazing in a low Se pasture were studied. The selenium status of calves which were born from selenium treated cows were higher than that in calves from untreated control cows during the suckling period. Selenium supplementation to the dams showed no significant response upon the body measurement for their calves at birth or four months of age, but significant improvement in body weight and withers height at the weaning period. When cows grazed continuously in pastures containing a selenium content of …
Plant Introduction, Seed Production And Fodder Promotion In An Integrated Livestock And Pasture Development Programme In Kerala, India, A Shamsudeen, T V. Joseph, F Von Sury
Plant Introduction, Seed Production And Fodder Promotion In An Integrated Livestock And Pasture Development Programme In Kerala, India, A Shamsudeen, T V. Joseph, F Von Sury
IGC Proceedings (1977-2023)
An integrated pasture development programme for the state of Kerala, in the 1500-3500 mm rainfall area of southern India, is described. Kerala's agriculture is characterized by small holdings and intensive multicrop farming systems with coconut and rice as main crops. Dairy cattle rearing is an important subsidiary for many farmers. A plant introduction programme selected Panicum maximum ( cvs. Makueni and Riversdale), Brachiaria ruziziensis and Centrosema pubescens for intercropping in coconut gardens. Desmodium intortum and D. uncinatum were introduced for the grasslands of the high ranges. B. ruziziensis, Melinis minutiflora, Setaria anceps ( cvs. Kazungula and N arok), Stylosanthes guianensis …