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Effects Of Level And Source Nitrogen Fertilzier On The Pure Seed Yield Of Setaria Sphacelata Cv. Narok In Yunnan Province, Southern China, Li Shuan, Zhao Jun-Quan Apr 2025

Effects Of Level And Source Nitrogen Fertilzier On The Pure Seed Yield Of Setaria Sphacelata Cv. Narok In Yunnan Province, Southern China, Li Shuan, Zhao Jun-Quan

IGC Proceedings (1977-2023)

Setaria sphacelata is a widely sown pasture grass in the tropics and sub-tropics (Hacker and Jones, 1969). Its use is lim­ited by low seed yields (10-80 kg/ha/crop) and the cold tolerant cv. Narok gives less seed than other cultivars (Bahnisch and Humphreys, 1977). In Queensland Setaria generally produces two crops a year with irrigation, but the seed yields are some of the lowest of any commercial species traded (Humphreys and Riveros, 1986). The objet of the present experimental work was to determine the optimum level of nitrogen and its time of application for maximum profit, and to study the seed …

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Effects Of The Growth Regulators Rsw 0411 In Seed Crops Of Lolium Perenne, Poa Pratensis And Festuca Rubra, G.E L. Borm, S Vreeke Apr 2025

Effects Of The Growth Regulators Rsw 0411 In Seed Crops Of Lolium Perenne, Poa Pratensis And Festuca Rubra, G.E L. Borm, S Vreeke

IGC Proceedings (1977-2023)

To increase yields and yield stability in grass seed crops use of the growth regulator RSW 0411 has been investigated since 1984. The effects of application of this growth regulator at different rates and different stages of development in Lolium perenne, Poa pratensis and Festuca rubra are presented in this paper.

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The Potential For Pasture Seed Production In Yunnan Province, Southern China, Li Shuan Apr 2025

The Potential For Pasture Seed Production In Yunnan Province, Southern China, Li Shuan

IGC Proceedings (1977-2023)

The objective of the seed production team has been to develop commercial seed production capabilities in the Yunnan Livestock and Pasture Development Project areas in Yunnan (Vaughan, 1987). It is mainly a mountainous area with altitudes ranging from 86 min the SE to 6,580 m in the NW. Since 1983, 523 cultivars or breeding materials of many trop­ical, transitional and temperate species have been introduced for evaluation at 13 sites in different ecological zones. About 90 cultivars show good adaption and produce high yields of dry matter.

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Determination Of The Optimum Harvest Time On Andropogon Gayanus Ciat 621, Yolanda Gonzales, F Mendoza Apr 2025

Determination Of The Optimum Harvest Time On Andropogon Gayanus Ciat 621, Yolanda Gonzales, F Mendoza

IGC Proceedings (1977-2023)

The seed harvest of Andropogon gayanus is obstructed by inherent characteristics of the cultivar such as the flowering dis­tribution and the notably absence of uniformity of its flowering and maturity ; therefore, it is necessary to determine precisely the optimum harvest time which will be the objective of this study.

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The Effect Of Fungicide Application On Seed Yield Of Dactylis Glomerata, R E. Welty Apr 2025

The Effect Of Fungicide Application On Seed Yield Of Dactylis Glomerata, R E. Welty

IGC Proceedings (1977-2023)

Leaf diseases of orchardgrass (Dactylis glomerata L.) caused by Mastigosporium rubricosum (Dearn. and Barth.) Nannf. (eyespot), Rhyncosporium orthosporum Caldwell (scald), and Cercosporidium (Scolecotrichum) graminis Fckl. (leaf streak) are widely distributed in the seed-producing area in Oregon (Sprague, 1950). These diseases may occur alone or in combi­nation and are more severe when weather is cool and wet. Symptoms develop in February and can extend through June. In most years, all three diseases can be found on individual plants in April and May. The diseases cause premature death of leaves, but not defoliation. When severe on the upper leaves (the flag …

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Fungicide Effect On Temperate Forage Grasses, M P. Rolston, J G. Hampton, M D. Hare, R E. Falloon Apr 2025

Fungicide Effect On Temperate Forage Grasses, M P. Rolston, J G. Hampton, M D. Hare, R E. Falloon

IGC Proceedings (1977-2023)

The traditional use of fungicides in temperate forage grass seed crops has been for the control of diseases. However, in perennial ryegrass (Lolium perenne L.) seed crops, fungicides applied close to anthesis have increased seed yields even where the incidence· of leaf pathogens was low (Hampton and Heb­blethwaithe, 1984, 1985; Hampton et al., 1985). The response was attributed to increased leaf area duration by delaying the senescence of photosynthetic tissue. In another trial in which levels of stem rust (Puccinia graminis Pers) were low, fungicides also increased perennial ryegrass seed yield. The response was associated with both disease …

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Effect Of Fungicides On Perennial Ryegrass Seed Production, G H. Horeman Apr 2025

Effect Of Fungicides On Perennial Ryegrass Seed Production, G H. Horeman

IGC Proceedings (1977-2023)

Significant seed yield increases were obtained (Hampton and Hebblethwaite, 1984) to fungicide application before ear emergence only, but the effects of fungal pathogens on the rye­ grass seed crop could not be assessed. After application of _ propiconazol before anthesis significant seed yield increases were obtained, even in absence of fungal pathogens (Horeman 1987). In this paper results of two experiments are presented. The aim was to investigate whether yield increases after fungicide application is consistent over the years and to find an explanation for these increases.

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Breeding In Progress For Seed Retention In Orchardgrass (Dactylis Glomereata L.), M Falcinelli, V Negri, F Veronesi Apr 2025

Breeding In Progress For Seed Retention In Orchardgrass (Dactylis Glomereata L.), M Falcinelli, V Negri, F Veronesi

IGC Proceedings (1977-2023)

As is well known, orchardgrass seeds do not mature and ripen uniformly and early maturing seeds frequently shatter before late developing ones mature. Consequently, in seed crops, high losses can either be due to early'harvesting resulting in an excess of light seeds, or to delayed harvesting resulting in seed shattering. Several agronomic strategies are used by seed producers to minimize seed losses, but the additional costs involved have limited their adoption. Previous papers (Falcinelli et al., 1983 ; 1984) have reported that many populations of D. glomerata from Southern Italy and some populations from Central Italy showed no seed shattering …

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Effect Of Frost On Panicle Production In Dactylis Glomerata, O T. Niemelainen Apr 2025

Effect Of Frost On Panicle Production In Dactylis Glomerata, O T. Niemelainen

IGC Proceedings (1977-2023)

The average seed yield of cocksfoot in Finland is small. The panicle formation has often been poor although the stand has otherwise been in good condition. In the present study the importance of early summer frost on the failure of panicle for­mation in cocksfoot was studied. The cold tolerance of cocks­foot has been observed to be poor compared to other perennial grasses (Gudleifsson et al., 1986). The sensitivity of cocksfoot to frost during the growing season was observed in the exper­iment of Nikolaevskaya (1973) where a frost treatment at flowering stage of cocksfoot completely destroyed the caryopses. Results of experiments …

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A Comparison Of Rhizome And Seed Propagation Of Three Grasses Of Nei Mongol: Chinese Wildrye, Tender Pennisteum And Reedlike Foxtail, Na Sen, Lee Yan Qin, Su Xiao Lin Apr 2025

A Comparison Of Rhizome And Seed Propagation Of Three Grasses Of Nei Mongol: Chinese Wildrye, Tender Pennisteum And Reedlike Foxtail, Na Sen, Lee Yan Qin, Su Xiao Lin

IGC Proceedings (1977-2023)

China is making great efforts to re-vegetate and improve her rangelands. In Inner Mongolia, improvement and expansion of the rangeland base is necessary to meet the needs of a flourish­ing local livestock industry, and growing demand for livestock products (including draft animals) in China as a whole. But the harsh growing conditions in this cold, dry and windy steppe country make seedling establishment difficult, and propagation with seed is risky at best. Methods of grassland propagation that minimize this risk, reduce the rest period after planting, and result in a more productive range will aid the revegetation effort considerably, and …

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The Effect Of Megachilla Rotundata On The Yield And Qualitative Characters Of Alfalfa Seed, B Radenovic, S Starcevic Apr 2025

The Effect Of Megachilla Rotundata On The Yield And Qualitative Characters Of Alfalfa Seed, B Radenovic, S Starcevic

IGC Proceedings (1977-2023)

The increasing use of insecticides in the Yugoslav agriculture, ploughing of meadows and pastures and the expan­sion of areas under alfalfa grown for seed have resulted in the reduction of useful entomofauna and thus also in the decline of yields of alfalfa seed due to the reduced number of pollinators. This was first indicated upon in the United States, by Knowels, 1943, and in Yugoslavia, it was pointed out by Bosnjak, 1978 and Radenovic and Starcevic, 1982. All these authors agree that there is a positive correlation between the number of Megachillidae, the number of open flowers and embryos. According …

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Determination De L’Effet Du Phosphore Et Des Intervallets D’Irrigation Sur La Production De Graines De Trefle Bersim En Iran, A Vaez Zadeh Apr 2025

Determination De L’Effet Du Phosphore Et Des Intervallets D’Irrigation Sur La Production De Graines De Trefle Bersim En Iran, A Vaez Zadeh

IGC Proceedings (1977-2023)

La culture du trefle Bersim (Trifolium alexandrinum) devient de plus en plus importante en Iran. Elle est pratiquee dans les rizieres apres la recolte du riz. Aujourd'hui, cette culture s'etend sur 40.000 ha et la production atteint 500.000 tonnes de foin sec, soit un rendement moyen de 12.5 t/ha. Le ministere de !'Agriculture developpe un important programme pour augmenter la superficie jusqu'a 200.000 ha. Ceci correspondra a la moitie de toutes Jes rizieres. La culture du trefle Bersim s'est fortement developpee pen­dant ces dernieres annees en Iran: la superficie a augmente de 578,5 ha en 1982 a 39.500 …

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Seed Yield, Fodder Yield And Persistence In White Clover Cvs Of Different Origins. Results Of Trials Conducted At Lodi (Irrigated Po Valley), R Paoletti, C Locattello Apr 2025

Seed Yield, Fodder Yield And Persistence In White Clover Cvs Of Different Origins. Results Of Trials Conducted At Lodi (Irrigated Po Valley), R Paoletti, C Locattello

IGC Proceedings (1977-2023)

White clover is the most important pasture legume in many EEC countries (white clover-ryegrass pasture system) and a good component of permanent and rotated polyphytic meadows in North Italy (irrigated Po Valley where the Ladino subspecies developed through self selection). The main char­acteristics of the species are N2 fixation and high nutritional value (quality). Therefore, white clover seed usage in the EEC is expected to still be important in the next decades. A number of performing varieties have recently been developed by EEC Research Institutes. An assessment of their seed production potential is necessary in view of self-sufficiency and consequent …

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Inoculant Production With Gamma Irradiated Peat And Lyophilized Cultures Of Rhizobium. Survival On Pelleted Seeds And Mineral Oil, M Lopez, R S. Bradley Apr 2025

Inoculant Production With Gamma Irradiated Peat And Lyophilized Cultures Of Rhizobium. Survival On Pelleted Seeds And Mineral Oil, M Lopez, R S. Bradley

IGC Proceedings (1977-2023)

In tropical countries one of the ways of improving inoculant distribution consists on seed-pre-inoculation and on the pro­duction of lyophilized inoculants allowing a higher viability during the storage period. Thus, it is necessary to learn the rhizobium survival in pre-inoculated seeds and in lyophilized flasks, as well as in mineral oil used as a rhizobium carrier.

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Les Inineraires Techniques Pour La Production De Semences De Trefle Blanc En France, J Aletru, Y Bouchet Apr 2025

Les Inineraires Techniques Pour La Production De Semences De Trefle Blanc En France, J Aletru, Y Bouchet

IGC Proceedings (1977-2023)

Le Trefle blanc est une legumineuse fourragere ayant une morphologie et une physiologie tout a fait originales par rapport aux autres especes fourrageres que nous avons l'habitude de travailler : luzerne, trefle violet, sainfoin, etc. Le Trefle blanc a un port rampant, l'essentiel de la croissance s'effectue horizontalement, Jes parties aeriennes sont consti­tuees de petioles, de feuilles en phase vegetative, auxquelles s'ajoutent des pedoncules et des inflorescences en phase repro­ductrice. Le stolon, « colonne vertebrale » des parties aeriennes, est l'organe de reserve ayant une importance preponderante. II colonise le sol en emettant de 70 a 110 metres de stolons …

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Environmental Considerations For Lotus Production: Seed Versus Herbage, P R. Beuselinck, R L. Mcgraw Apr 2025

Environmental Considerations For Lotus Production: Seed Versus Herbage, P R. Beuselinck, R L. Mcgraw

IGC Proceedings (1977-2023)

Broadleafed birdsfoot trefoil (Lotus corniculatus L.), is recognized for good productivity on marginal soils (Seaney and Henson, 1970), high feeding value (Marten and Ehle, 1984), stock-piling efficiency (Collins, 1982) and freedom from bloat­inducement in ruminants (Marten and Jordan, 1979) makes it a worthy herbage crop for many areas and grazing situations. The most productive USA areas are New England, the West Coast, the North Central Plains, and some isolated areas of higher elevations in the South (Grant and Marten, 1985). Difficulty in harvesting sufficient quantities of seed is a major factor limiting the use and production of birdsfoot trefoil in …

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Agricultural Behaviour Of Lablab Purpureus Cv. Rongai Under Cuban Conditions, V A. Remy, C Matias, A Perez, M Beavogui Apr 2025

Agricultural Behaviour Of Lablab Purpureus Cv. Rongai Under Cuban Conditions, V A. Remy, C Matias, A Perez, M Beavogui

IGC Proceedings (1977-2023)

Production strategy of livestock in Cuba is based upon the utilization of swards as the main feeding source. Nevertheless, the climatical conditions that exist in certain period of the year lead to a seasonal productive unbalance due to the decreasing sequence of rainfall. Several alternatives have been adopted against this situation and one of them is the utilization of tem­porary cultivars. Taking into consideration the previous situation, the possi­bility of spreading Lablab purpureus, the suitable growth that it presents under temperatures among 18-30 °C (Duke, 1983), rainfall among 200-2500 mm (National Academy of Science, 1979) and its seed production from …

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Influence Of The Manner Of Sowing And Vegetation Cycle On The Yield And Seed Quality Of Birdfoot Trefoil (Lotus Corniculatus), D Gataric, S Alibegovic-Grbic Apr 2025

Influence Of The Manner Of Sowing And Vegetation Cycle On The Yield And Seed Quality Of Birdfoot Trefoil (Lotus Corniculatus), D Gataric, S Alibegovic-Grbic

IGC Proceedings (1977-2023)

In ecological conditions of Yugoslavia, birdsfoot trefoil, with its positive features, presents a very significant fodder crop, especially for the hill and mountain regions. However, due to poor seed production technology, there is a shortage of seed for more intensive production. Seed is usually produced on areas intended for the production of fodder, hand sown with large quantities of seed (25-35 kg/ha). The study was undertaken. with the following targets : I/determining the influence of the manner of sowing and veg­etation cycle on the yield and the quality of seed ; 2/ determin­ing the optimum sowing manner and vegetation cycle …

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Nouvelles Possibilites De Lutte Contre Les Ravageurs De La Luzerne Porte-Graine En France, J Hacquet Apr 2025

Nouvelles Possibilites De Lutte Contre Les Ravageurs De La Luzerne Porte-Graine En France, J Hacquet

IGC Proceedings (1977-2023)

La mai'trise des insectes ravageurs dans la luzerne porte­graine est une necessite pour l'obtention de rendements eleves et reguliers. La collaboration etroite entre le Service Technique de la FNAMS et la Laboratoire de Zoologie de l'INRA de Lusignan a permis d'inventorier les differents ravageurs, de mettre au point une panoplie de traitements et de faire connai'­tre les moyens de lutte aupres de tous Jes praticiens de cette cul­ture (FNAMS-INRA, 1980 et 1986). De plus des reseaux d'Avertissements Agricoles ont ete mis en place et suivis par le Service de la Protection des Vegetaux, avec la participation des professionnels (Perron, 1987). …

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Variation Of Seed Yield And Its Components In Common Vetch (Vicia Sativa L.) Under Different Conditions, E Acikgoz, I Turgut, H Ekiz Apr 2025

Variation Of Seed Yield And Its Components In Common Vetch (Vicia Sativa L.) Under Different Conditions, E Acikgoz, I Turgut, H Ekiz

IGC Proceedings (1977-2023)

Common vetch (Vicia sativa L.) is widely used as a seed or hay crop in Turkey. In humid coastal areas it is principally used fot hay or green herbage while in dry regions it is used mostly for seed. Roughly ground vetch seed is a popular concentrated feed and mixed with straw or cereal grain (A9ikg6z, 1988). Approximately 200.000 ha of common vetch are seeded every year in Turkey. It is sown mostly as a spring-seeded crop and is often subjected to severe heat and drought stress as the season progress. Yields are generally low with an average seed …

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White Clover Seed Production In Two Mediterranean Environments Of Tuscany And Sardinia, P Bullitta, Simonetta Bullitta, A Pardini, S Piemontese, P P. Roggero, P Talamucci Apr 2025

White Clover Seed Production In Two Mediterranean Environments Of Tuscany And Sardinia, P Bullitta, Simonetta Bullitta, A Pardini, S Piemontese, P P. Roggero, P Talamucci

IGC Proceedings (1977-2023)

Purpose of the trialwas the identification of the most suitable varieties for white clover Trifolium repens L. seed production in Mediterranean environments. The main reason of this paper is to verify whether it is possible to produce seed of European varieties of white clover in south Europe considering that surfaces for seed production are decreasing in the northern European countries that were normally producers of white clo­ver seed. The production of clover seed in southern Europe could advantageously replace the import from New Zealand and California.

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Vegetative Propagation Of White Clover An Application In White Clover Seed Production, P C.D Newton, A I. Popay Apr 2025

Vegetative Propagation Of White Clover An Application In White Clover Seed Production, P C.D Newton, A I. Popay

IGC Proceedings (1977-2023)

Establishment of white clover for agricultural purposes is invariably by seed. However, natural regeneration is almost entirely vegetative (Chapman, 1987), and flowering may be restricted to a small proportion of individuals within a popu­lation (Burdon, 1980) When white clover is present in the soil seedbank, there is potential for both intra- (between classes) and inter-varietal contamination of seed crops. Lancashire et al., (1985) have commented that genetic contamination of white clover seed is a world-wide problem. Volunteer seedlings may be removed from between the crop rows mechanically, but there remains an untreatable area close to the crop which is available …

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Viability Of Stylosanthes Seeds As Affected By Storage Duration, J B. Brolmann, B J. Boman Apr 2025

Viability Of Stylosanthes Seeds As Affected By Storage Duration, J B. Brolmann, B J. Boman

IGC Proceedings (1977-2023)

Tropical legumes such as members of the genus Stylosanthes (sty lo) contribute to the improvement of pastures in the tropics and sub-tropics. Stylosanthes is usually established from seed. In Florida, seed of Stylosanthes has to be produced and col­lected before the onset of the winter since occasional frosts can damage seed-bearing vegetation. Therefore, early maturing Stylosanthes varieties have been developed. In stylo seed collections maintained for breeding or seed exchange purposes, maintenances of seed viability is critical. New pests or new diseases may require a renewed screening of stored accessions. It is important, then, that the seed source of this …

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Modification Of Stolon Growth, Development And Flowering By Plant Growth Regulators In White Clover (Trifolium Repens L.) Seed Crops, A H. Marshall, D H. Hides Apr 2025

Modification Of Stolon Growth, Development And Flowering By Plant Growth Regulators In White Clover (Trifolium Repens L.) Seed Crops, A H. Marshall, D H. Hides

IGC Proceedings (1977-2023)

Within the EEC the need to develop low cost less intensive systems of animal production has led to an increase in the importance of legumes generally, and white clover in particu­lar. At present, annual white clover seed usage within the EEC is approximately 4,000 tonnes, however, the self sufficiency rate is expected to fall below 50 % by the end of the 1980s due prin­cipally to unpredictable seed yields which make it an unprofit­able crop for seed growers. The main component of seed yield in white clover is the number of ripe inflorescences at harvest (Zaleski, 1961) however, the proportion …

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Growth Regulator Effects On Seed Production Of Lotus Corniculatus L. And Lotus Uliginosus Schkuhr., J G. Hampton, Qingfeng Li, M D. Hare Apr 2025

Growth Regulator Effects On Seed Production Of Lotus Corniculatus L. And Lotus Uliginosus Schkuhr., J G. Hampton, Qingfeng Li, M D. Hare

IGC Proceedings (1977-2023)

Seed yield in both Lotus corniculatus L. and Lotus uliginosus Schkuhr. (syn. L. pedunculatus Cav.) is considered to be limited by the indeterminate growth habit which results in a protracted (2-4 month) flowering period (Witchwoot, 1987; Li and Hill, 1988) leading to wide variation in seed maturity and seed loss through pod shattering. In both species seed yield is determined primarily by the number of inflorescences (Mos, 1983 ; Wit­chwoot, 1987), and thus treatments which alter or remove api­cal dominance, enhance shoot production or main stem bran­ching thereby increasing inflorescence numbers (Clifford et al., 1983 ; Li and Hill, 1988), …

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Plant Resources And Forage Seed Production In China, Dong Peihua Apr 2025

Plant Resources And Forage Seed Production In China, Dong Peihua

IGC Proceedings (1977-2023)

China is situated in the Eastern part of Asia ; from North to South it extends across the temperate and tropical zones. From East to West it has humid, semiarid, arid regions. There is no frost through the year in some part ofHainan Island, Yunnan, Guangdong and Taiwan provinces. Therefore plants grow the year round and there is a wide range of tropical species. The geographical and climatical differences resulted in rich grass resources. There are three hundred million hectares of natural pastures in Northern China, with more than 4000 plant species. These plants have different degrees of feeding value. …

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The Acth Test Fails To Diagnose Adrenal Insufficiency And Augments Cytokine Production In Sepsis, Dan Hao, Qian Wang, Misa Ito, Jianyao Xue, Ling Guo, Bin Huang, Chieko Mineo, Philip W. Shaul, Xiang An Li Apr 2025

The Acth Test Fails To Diagnose Adrenal Insufficiency And Augments Cytokine Production In Sepsis, Dan Hao, Qian Wang, Misa Ito, Jianyao Xue, Ling Guo, Bin Huang, Chieko Mineo, Philip W. Shaul, Xiang An Li

Physiology Faculty Publications

The adrenocorticotropic hormone (ACTH) test diagnoses relative adrenal insufficiency (RAI) or critical illness–related corticosteroid insufficiency (CIRCI). Initially, guidelines recommended corticosteroid/glucocorticoid (GC) therapy for septic patients with RAI, but later trials did not show a survival benefit, leading to updated guidelines that abandon targeting RAI or CIRCI. Recent studies with an RAI mouse model showed a clear survival benefit from GC therapy in mice with RAI, suggesting that inconclusive GC clinical trials might be due to issues with the ACTH test rather than targeting RAI. To investigate, we performed the ACTH test in septic mice. Interestingly, the ACTH test identified most …

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Steroid Receptors And Coregulators: Dissemination Of Sex Differences And Emerging Technologies, Sally Pauss, Evelyn A. Bates, Genesee J. Martinez, Zane T. Bates, Zachary A. Kipp, Cassandra D. Gipson, Terry D. Hinds Jr. Apr 2025

Steroid Receptors And Coregulators: Dissemination Of Sex Differences And Emerging Technologies, Sally Pauss, Evelyn A. Bates, Genesee J. Martinez, Zane T. Bates, Zachary A. Kipp, Cassandra D. Gipson, Terry D. Hinds Jr.

Markey Cancer Center Faculty Publications

Steroid receptors are ligand-induced transcription factors that have broad functions among all living animal species, ranging from control of sex differences, body weight, stress responses, and many others. Their binding to coregulator proteins is regulated by corepressors and coactivators that interchange upon stimulation with a ligand. Coregulator proteins are an imperative and understudied aspect of steroid receptor signaling. Here, we discuss steroid receptor basics from protein domain structures that allow them to interact with coregulators and other proteins, their essential functions as transcription factors, and other elemental protein–protein interactions. We deliberate about the mechanisms that coregulators control in steroid receptor …

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Lysyl Hydroxylase 2 Glucosylates Collagen Vi To Drive Lung Cancer Progression, Shike Wang, Houfu Guo, Reo Fukushima, Masahiko Terajima, Min Liu, Guan-Yu Xiao, Lenka Koudelková, Chao Wu, Xin Liu, Jiang Yu, Emma Burris, Jun Xu, Alvise Schiavinato, William K. Russell, Mitsuo Yamauchi, Xiaochao Tan Apr 2025

Lysyl Hydroxylase 2 Glucosylates Collagen Vi To Drive Lung Cancer Progression, Shike Wang, Houfu Guo, Reo Fukushima, Masahiko Terajima, Min Liu, Guan-Yu Xiao, Lenka Koudelková, Chao Wu, Xin Liu, Jiang Yu, Emma Burris, Jun Xu, Alvise Schiavinato, William K. Russell, Mitsuo Yamauchi, Xiaochao Tan

Markey Cancer Center Faculty Publications

Lysyl hydroxylase 2 (LH2) is highly expressed in multiple tumor types and accelerates disease progression by hydroxylating lysine residues on fibrillar collagen telopeptides to generate stable collagen cross links in tumor stroma. Here, we show that a galactosylhydroxylysyl glucosyltransferase (GGT) domain on LH2 modified type-VI collagen (Col6) to promote lung adenocarcinoma (LUAD) growth and metastasis. In tumors generated by LUAD cells lacking LH2 GGT domain activity, stroma was less stiff, and stable types of collagen cross links were reduced. Mass spectrometric analysis of total and glycosylated peptides in parental and GGT-inactive tumor samples identified Col6 chain α3 (Col6a3), a component …

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The Role Of Race/Ethnicity On The Association Between Neighborhood Deprivation And Breast Cancer Outcomes Among Kentucky Patients With Breast Cancer (2010–2022), Breyanna Walker, Elinita Pollard, Sydney P. Howard, V. Morgan Jones, Kathleen L. O’Connor, Eric B. Durbin, Pamela C. Hull, Samantha R. Jones, Adebola Adegboyega, Xiaoqin Wang, Wendi A.B. Owen, Margaret M. Szabunio, Lovoria B. Williams, Justin X. Moore Apr 2025

The Role Of Race/Ethnicity On The Association Between Neighborhood Deprivation And Breast Cancer Outcomes Among Kentucky Patients With Breast Cancer (2010–2022), Breyanna Walker, Elinita Pollard, Sydney P. Howard, V. Morgan Jones, Kathleen L. O’Connor, Eric B. Durbin, Pamela C. Hull, Samantha R. Jones, Adebola Adegboyega, Xiaoqin Wang, Wendi A.B. Owen, Margaret M. Szabunio, Lovoria B. Williams, Justin X. Moore

Surgery Faculty Publications

Background: Kentucky is within the top five leading states for breast cancer mortality nationwide. This study investigates the association between neighborhood socioeconomic disadvantage and breast cancer outcomes, including surgical treatment, radiotherapy, chemotherapy, and survival, and how associations vary by race and ethnicity in Kentucky. Methods: We conducted a retrospective cohort analysis using data from the Kentucky Cancer Registry for patients with breast cancer diagnosed between 2010 and 2017, with follow-up through December 31, 2022. We linked Kentucky Cancer Registry data with census tract data to examine the relationship between area deprivation index (ADI) and breast cancer outcomes. Logistic regression and …

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