Digital Commons Network^™

A Review Of The Pharmacology, Pharmacokinetics And Behavioral Effects Of Procaine In Thoroughbred Horses, Thomas Tobin, J. W. Blake

Maxwell H. Gluck Equine Research Center Faculty Publications

Since procaine has both local anaesthetic and central stimulant actions its presence in the blood or urine of racing horses is forbidden. After rapid intravenous injection of procaine HC1 (2.5 mg/Kg) in thoroughbred mares plasma levels of this drug fell rapidly (t 1/2 alpha = 5 min) and then more slowly (t 1/2 beta = 50.2 min). These kinetics were well fitted by a two compartment open model (Model I). This model gave an apparent Vdbeta for procaine in the horse of about 3,500 litres. Since procaine was about 45% bound to equine plasma protein this gives a true Vdbeta …

The Gas-Liquid Chromatograph And The Electron Capture Detection In Equine Drug Testing., J. W. Blake, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Three gas-liquid chromatographic (G.L.C.) procedures discussed have been designed around the four "esses" of detection tests--speed, sensitivity, simplicity, and specificity. These techniques are admirably applicable to the very low plasma drug levels encountered in blood testing under pre-race conditions. The methods are equally applicable to post-race testing procedures, where both blood and urine samples are tested. Drugs can only rarely be detected by the electron capture detector (E.C.D.) without a prior derivatization step, which conveys to the drug(s) high electron affinity. Because of broad applicability, two derivatizing agents, heptafluorobutyric (HFBA) and pentafluorpropionic (PFPA) anhydrides are employed. The three techniques, allowing …

Upward Water Movement In Field Cores, Larry G. Wells, R. W. Skaggs

Biosystems and Agricultural Engineering Faculty Publications

No abstract provided.

Surface Mining And Environmental Quality: An Economic Perspective, Alan Randall, Angelos Pagoulatos

Kentucky Law Journal

No abstract provided.

Kentucky Law Survey: Torts, Richard Ausness

Kentucky Law Journal

No abstract provided.

Kentucky Law Survey: Domestic Relations, Natalie S. Wilson

Kentucky Law Journal

No abstract provided.

Analysis Of The Sediment Filtering Action Of Grassed Media, Billy J. Barfield, David T. Y. Kao, E. W. Tollner

KWRRI Research Reports

The movement of sediment in non-submerged flow through a rigid grass media was studied experimentally by simulating the media with cylindrical nails. Models of sediment movement were developed from probablistic reasoning and from the use of existing parameters describing total bed material in open channel flow. In the probability analysis, the percent sediment trapped was found to be a power function of the number of potential fall paths, N_f,a particle could make from the surface to the bed while traveling through the filter media. The percent trapped was also found to be an inverse power function of the …

Tertiary Treatment Of Wastewater Using Oxidation Ponds, Robert A. Lauderdale, John R. Moeller, Raymond D. Hamilton

KWRRI Research Reports

The purpose of the project was to determine the value of using lagoons as a supplemental process for treating the effluent from an activated sludge wastewater treatment plant.

Only tentative conclusions can be suggested since the project was not carried to completion. It appears that lagoons will have only minimal effect on the amounts of total nitrogen and phosphate in the plant effluent, although conversion of a portion of the ammonia to nitrate can be expected. However, the concentration of ammonia was never lower than that required by EPA guidelines. Some reduction of soluble BOD appears to occur, perhaps through …

College Of Law Commencement Program, 1975, University Of Kentucky

Graduation Programs

No abstract provided.

Evaluation Of Recovery In A Polluted Creek After Installation Of New Sewage Treatment Procedures, Robert A. Kuehne

KWRRI Research Reports

Response of Hickman Creek near Lexington, Kentucky to alleviation from serious sewage pollution was studied from January, 1973 through July, 1974. Wastes are now handled from an efficient secondary treatment facility and four sequential polishing lagoons before chlorination and discharge to West Hickman branch.

Physico-chemical tests gave no strong indication of residual pollution effects at the start of the study, approximately six months after the treatment facility opened. At low flow a slight oxygen sag, probably associated with algal growth in the lagoons, persists downstream from the outfall. Mean values for turbidity, nitrates and COD are somewhat higher at the …

Process Control Of Activated Sludge Treatment, Phase Ii, Richard I. Kermode, Robert W. J. Brett, Joseph D. Pault Jr.

KWRRI Research Reports

Material balances on substrate and microorganisms were derived in conjunction with various mixing configurations thought to accurately describe the activated sludge process. These models include the completely mixed with bypass, plug flow, and plug flow with bypass. Two sets of kinetic mechanisms for substrate utilization and bacterial growth were employed.

A feed forward controller was designed from linear approximations of the material balances derived in the completely mixed with bypass mixing model. Utilizing frequency response methods, the controller was found essentially identical to a completely mixed modeled controller developed in a prior investigation.

Through computer simulation the controller's effectiveness was …

Viability And Abortion, Chris Macaluso

Kentucky Law Journal

No abstract provided.

A Study Of Naturally Occurring Algicides Produced By Freshwater Algae, Denny O. Harris, Harry D. Caldwell

KWRRI Research Reports

The mode of action of the algicide produced by Pandorina morum was examined by exposing Volvox globator and isolates spinach chloroplasts to a partially purified algicide preparation. Oxygen evolution of Volvox, whole chloroplasts and broken chloroplasts (minus the Calvin cycle),was reduced indicating that the algicide inhibits the light reactions of photosynthesis. Oxygen evolution studies of other Volvocaceae confirmed the observation that Pandorina morum is not significantly influenced by its own inhibitor. Molecular weight approximation by gel filtration established that the inhibitor has a low molecular weight (probably below 100 mw). Field studies indicate that this algicide has tremendous potential as …

Metabolic Capabilities Of Sulfur Oxidizing Bacteria And Their Role In Water Pollution, M. I. H. Aleem

KWRRI Research Reports

This report describes investigations into the physiology of microorganisms that are commonly involved in the oxidation of inorganic sulfur compounds. The metabolic activities of these bacteria play a potent role in several fields of economic importance such as strip mining operations, water pollution, corrosion, metallurgy, petroleum technology and soil fertility processes.

The oxidation of inorganic sulfur compounds was studied in the chemolithotrophs Thiobacillus denitrificans, Thiobacillus A₂, Thiobacillus neapolitanus, and a photolithotroph Rhodopseudomonas palustris. Cell suspensions from all of the thiobacilli catalyzed completely the oxidation of sulfide, thiosulfate, and sulfite to sulfate. The oxidation of thiosulfate in R. palustris …

Seasonal Changes In Water Quality And Primary Productivity In Doe Valley Lake, Edmond J. Bacon, Stuart E. Neff

KWRRI Research Reports

Primary productivity and water quality were studied in Doe Valley Lake, a 147-hectare impoundment on Doe Run, a spring-fed stream in Meade County, Kentucky, from 13 June 1969 to 31 July 1972. Doe Valley Lake is monomictic during most winter seasons, but it is dimictic during more severe winters because of its morphometry and location on the borderline climatic region for dimictic lakes (37° N latitude). Oxygen depletion in the hypolimnion is severe, and anaerobic conditions usually prevail by late June. A hypolimnetic areal deficit of 0.038 mg/cm²/day was calculated. Supersaturation of oxygen in the epilimnion was common, …

Development Of Prediction Relationships For Water Requirements With Irrigation Cooling, Billy J. Barfield, John N. Walker, F. A. Payne

KWRRI Research Reports

A model for predicting leaf temperatures during an off-on mist cycle is presented. The model uses a combination of energy budget and aerodynamic techniques. The model was tested for dry leaf temperature and evapotranspiration predictions using average hourly data from Arizona. The accuracy was good. It was also tested for dry leaf temperature predictions using two to three minute data with a widely varying net radiation. When reasonable values of stomatal resistance were used, the agreement was again good.

The model was tested for prediction of wet leaf temperature prediction with a ten minute on, fifty minute off mist irrigation …

The New Chastity And Other Arguments Against Women's Liberation By Midge Decter, Susan Grossman Alexander

Kentucky Law Journal

No abstract provided.

Measuring The Intangible Values Of Natural Streams, Part Ii, John A. Dearinger, George M. Woolwine, Charles R. Scroggin, Daniel R. Dolan, James S. Calvin

KWRRI Research Reports

This report describes the work done during Part II of a project which had as its aim the development of a way to quantify those intangible values peculiar to a small stream and its watershed. Part I was concerned with an application of the "uniqueness concept" in the evaluation of fifty-eight Kentucky streams. The results of this effort are in Report #40, U. K. Water Resources Institute (1971).

During the second part of the project:

1. A method was developed whereby peoples' preferences for natural landscapes could be measured. The method utilized projected color slides and a rating system based on …

A Study Of Water-Soluble Inhibitory Compounds (Algicides) Produced By Fresh-Water Algae, Denny O. Harris, Manhar C. Parekh

KWRRI Research Reports

A complex system of growth inhibitors was observed in the green algae (Volvocaceae). Inhibitors were found in the culture filtrates of some genera which limit their own growth (autoinhibitors) while others in the family produce substances which check the growth of other genera (heteroinhibitors). These inhibitors were destroyed by autoclaving. It was decided that Pandorina morum, which produced the strongest inhibitor and Volvox tertius, the most sensitive to the inhibitor would make an excellent model system for a study of the chemical and physical properties of these naturally occurring algicides. The algicide could be removed from actively growing cultures about …

A Detailed Investigation Of The Sociological, Economic, And Ecological Aspects Of Proposed Reservoir Sites In The Salt River Basin Of Kentucky, Stuart E. Neff, Louis A. Krumholz, John R. Baker, Daryl E. Jennings, Andrew C. Miller, Jerry S. Parsons, Vincent H. Resh, David S. White

KWRRI Research Reports

Samples of water, bottom fauna, and fishes were collected from 66 stations in the Salt River and one of its principal tributaries, the Beech Fork and its tributary, the Chaplin River, Kentucky. Precipitation ranged from 38.86 inches (1969) to 58.04 inches (1970), an increase of nearly 50 percent with marked fluctuations in discharge. Intensive comparisons of phosphates, sulfates, specific conductance, total alkalinity, total hardness, and turbidity showed the streams to be relatively clean and healthy. Nearly 300 different kinds of benthic organisms and other macroinvertebrates have been collected and identified from the basin. Detailed studies of caddisflies and stream drift …

Enzyme And Tissue Alterations In Fishes: A Measure Of Water Quality, David E. Hinton, M. W. Kendall, J. C. Koenig

KWRRI Research Reports

A variety of freshwater fishes were studied by light and electron microscopy, enzyme histochemical and biochemical methods, The objective was to determine normal structure and function in specific target organs and to compare these to altered states in aquatic pollution. The basic question, "can fish tissues and enzymes serve as indicators of water quality?," was asked. Microscopic alteration in gill was indicative of copper toxicity at an exposure of 20 parts per billion, Gross and light microscopic alterations were indicative of a single exposure of channel catfish to 15 parts per million of methyl mercuric chloride (CH₃HgCl). Microscopic …

Process Control Of Activated Sludge Treatment, Richard I. Kermode, Robert W. J. Brett, Kenneth A. Debelak, John J. Davis

KWRRI Research Reports

General feed forward controllers, conforming to standard control modes, have been derived for an activated sludge process. The analysis indicated that the appropriate controllers are proportional control with measurement of substrate flow rate, and derivative control with measurement of inlet substrate concentration, and manipulation of the rate of return sludge by both controllers.

The performance of these controllers was tested by computer simulation of five dynamic aerator models with and without sludge storage, and with two settling basin models. In all cases significant reduction of the maximum exit substrate concentration was achieved. Additional improvement resulted from the use of sludge …

College Of Law Commencement Program, 1973, University Of Kentucky

Graduation Programs

No abstract provided.

Tartan Surfacing For An Equestrian Overpass, Donald C. Newberry Jr.

Kentucky Transportation Center Research Report

The location of I 64 in Jefferson County traverses Seneca Park, noted for its scenic beauty and superior recreational facilities. A bridle path in Seneca Park necessitated construction of an overpass for equine traffic. A non-slip and sound-deadening, resilient surface was essential for aesthetics and safety. Tartan, a rubbery mat developed primarily for race course and paddock surfaces, was specified and installed on the overpass.

Land Use Controls In Coastal Areas, Richard C. Ausness

Law Faculty Scholarly Articles

Prolonged exploitation of coastal resources has caused extensive ecological harm. The alarming decline in the condition of the marine environment has become a matter of serious public concern. This Article will examine some of the environmental problems of the coastal zone and the resulting institutional responses. The first part will delineate a number of problems in the nation's coastal areas. The second part will review the doctrines of property law associated with the ownership of littoral land and their relation to land-use control measures. The third part will evaluate recent coastal management legislation. The fourth part will consider constitutional restraints …

Beyond Freedom And Dignity By B. F. Skinner, J. W. Torke

Kentucky Law Journal

No abstract provided.

The Relation Between Soil Characteristics, Water Movement And Nitrate Contamination Of Ground Water, Grant W. Thomas, Matthew Mcmahon

KWRRI Research Reports

Soils from several areas in Kentucky were placed in columns and leached with Ca(NO₃)₂. Subsoils high in iron oxide were found to retard the leaching of nitrate very significantly. In other soils, the nitrate moved through as fast as or slightly faster than the water.

Field application of nitrogen to corn was most efficient when done in the spring or summer near the time that the corn takes it up. The one exception to this was a red soil, where fall application of nitrogen resulted in little loss due to the retarding effect mentioned in the …

Carbon And Nitrogen As Regulators Of Algal Growth In Treated Sewage, Edward G. Foree, Charles Reece Scroggin

KWRRI Research Reports

Continuous flow algal cultures were grown under three different growth conditions using secondary sewage treatment plant effluent as the growth medium. The only variable within each run was the hydraulic residence time. The concentrations of growth regulating nutrients were varied between the runs so comparisons of the algal mass, composition, nutrient uptake, and genera could be made. The importance of CO₂ availability for algal growth was also studied. A kinetic theory which based algal growth on cellular nutrient concentration was verified. The second phase of the study was a batch culture study in which the same growth medium was …

Induced Changes In The Rates Of Uridine-3H Uptake And Incorporation During The G1 And S Periods Of Synchronized Chinese Hamster Cells, Peter J. Stambrook, Jesse E. Sisken

Biology Faculty Publications

The rates of uridine-5-³H incorporation into RNA and the rates of uridine uptake into the acid-soluble pool during the cell cycle of V79 Chinese hamster cells were examined. Cells cultured on Eagle's minimal essential medium supplemented with fetal calf serum, lactalbumin hydrolysate, glutamine, and trypsin displayed rates of incorporation and uptake which increased only slightly during G₁ and accelerated sharply as DNA synthesis commenced. In contrast, cells cultured on minimal essential medium supplemented only with calf serum exhibited rates of incorporation and uptake which increased linearly through both G₁ and S. The transition from one pattern …

Noise Pollution And Abatement: A Review Of Literature, Kenneth R. Agent, Robert C. Deen

Kentucky Transportation Center Research Report

Complaints concerning traffic noise and possibly seismic vibrations emanating from highways would probably have been adjudicated on the basis of common law doctrines pertaining to "nuisances", "common enemy'', and ''power of relief" were it not for recent legislation and regulations directed toward protection of the total environment. In effect, "freedom from noise" has been added to the clean water, clean air, clean earth policies. Surely each of those policies are founded on public sentiment.

There have been a few instances where the Department has yielded relief because of traffic noise. Now safeguarding regulations seem inevitable.

In the past, this Division …