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Rivers Of Earth And Troublesome Creeks: The Agrarianism Of James Still, H. R. Stoneback

The Kentucky Review

No abstract provided.

Puffing Biological Material, Frederick A. Payne

Biosystems and Agricultural Engineering Faculty Patents

A method and apparatus for puffing biological material such as fruits and vegetables are provided. The method includes the steps of: (a) placing the material in a pressure chamber; (b) subjecting the material to a puffing gas such as carbon dioxide at an increased pressure between substantially 400 and 1200 psi; (c) quickly releasing the puffing gas pressure in less than 1 second to puff the material; and (d) drying the material after puffing to set it in the puffed state. The material is prepared for puffing by sizing so as to include at least one dimension of between substantially …

Effects Of Aromatic Concentration On Methane Fermentation, Yi-Tin Wang, Pin-Chieh Pai, H. David Gabbard

KWRRI Research Reports

The anaerobic biodegradability and toxicity of fourteen aromatic compounds were evaluated over a wide range of concentrations using a serum bottle technique. Benzene, toluene, and all three isomers of xylene were not significantly degraded to methane in a phenol-enriched culture. Complete degradation of 1000 mg/L phenol, 800 mg/L catechol, 100 mg/L 2-NP, 100 mg/L 3- NP, and 100 mg/L 4-NP was observed within two months while depletion of 100 mg/L resorcinol and 1000 mg/L hydroquinone required more than six and eight months incubation, respectively. None of the three isomers of chlorophenol were degraded in the phenol-enriched culture. Batch toxicity assay …

Inability Of Mitogen-Activated Lymphocytes Obtained From Patients With Malignant Primary Intracranial Tumors To Express High Affinity Interleukin 2 Receptors, Lucinda H. Elliott, W. H. Brooks, T. L. Roszman

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Patients with primary malignant brain tumors manifest a variety of abnormalities in cell-mediated and humoral immunity. Diminished T cell reactivity has been shown in these patients to be linked to deficiencies in interleukin 2 (IL-2) production that cannot be overcome by exogenous IL-2. In this study, specific binding of radiolabeled IL-2 to PHA-stimulated lymphocytes from brain tumor patients demonstrates that the number of high affinity interleukin 2 receptors (IL-2R) is greatly reduced. FACS analysis indicates that the relative density of the p55 protein (Tac protein) is lower on the mitogen-activated lymphocytes obtained from patients than on comparably treated lymphocytes from …

Primary Antibody Responses To Thymus-Independent Antigens In The Lungs And Hilar Lymph Nodes Of Mice, S. Niranjan Goud, Alan M. Kaplan, Subbarao Bondada

Sanders-Brown Center on Aging Faculty Publications

B lymphocytes from the pulmonary lymphoid tissues were stimulated with a variety of thymus-independent (TI) antigens by intratracheal (i.t.) immunization. Immune responses in the lungs and hilar lymph nodes (HLN), which are part of the localized lymphoid tissue, as well as in the spleen, the systemic lymphoid organ, were studied. Thus, primary i.t. immunization of mice with the TI-1 antigen trinitrophenyl-lipopolysaccharide (TNP-LPS) elicited both antigen-specific and polyclonal plaque-forming cell responses from HLN, lung, and splenic B lymphocytes. These responses appeared as early as 3 days after immunization and declined by day 7. Similar immunization with another TI-1 antigen, TNP-Brucella …

Plasma Native And Peptidase-Derivable Met-Enkephalin Responses To Restraint Stress In Rats. Adaptation To Repeated Restraint, K. Pierzchala, G. R. Van Loon

Internal Medicine Faculty Publications

Met-enkephalin and related proenkephalin A-derived peptides circulate in plasma at picomolar concentration as free, native pentapeptide and at nanomolar concentration in cryptic forms. We have optimized conditions for measurement of immunoreactive Met-enkephalin in plasma and for generation by trypsin and carboxypeptidase B of much greater amounts of total peptidase-derivable Met-enkephalin in plasma of rats, dogs, and humans. Free Met-enkephalin (11 pM) is constituted by native pentapeptide and its sulfoxide. Characterization of plasma total Met-enkephalin derived by peptidic hydrolysis revealed a small amount (38 pM) of Met-enkephalin associated with peptides of molecular mass less than 30,000 D, and probably derived from …

Hay Additive Review: "Where We've Been, Where We're Going", William C. Mahanna, Steve Soderlund

Kentucky Alfalfa and Stored Forage Conference

The losses from harvest to feed bunk are undoubtedly greater with hay than any other crop grown by the American farmer. The economic implications of reducing losses through improved harvest technologies is staggering when one considers the 75-85 million tons of alfalfa harvested out of the total 140-145 million tons of hay produced annually in the United States.

Dna Fingerprinting: Evidence Of The Fuiture, Jane E. Hanner

Kentucky Law Journal

No abstract provided.

Macrophages But Not B Cells From Aged Mice Are Defective In Stimulating Autoreactive T Cells In Vitro, Aruna Seth, Mitzi Nagarkatti, Prakash S. Nagarkatti, Subbarao Bondada, Venkatachalam Udhayakumar

Microbiology, Immunology, and Molecular Genetics Faculty Publications

In the present study the effect of aging on the capacity of Ia⁺ cells to stimulate autoreactive T cells in the syngeneic mixed lymphocyte reaction (SMLR) was investigated. Using young CD4⁺ T cells as responders, it was observed that unseparated whole spleen cells from aged mice had normal stimulatory activity comparable to that of young spleen cells. Interestingly, however, when purified splenic adherant cells (SAC) enriched for macrophages or splenic B cells were used as stimulators, aged SAC but not aged B cells were found to be defective in stimulating autoreactive T cells. This defect in aged SAC …

Unavoidably Unsafe Products And Strict Products Liability: What Liability Rule Should Be Applied To The Sellers Of Pharmaceutical Products?, Richard C. Ausness

Kentucky Law Journal

No abstract provided.

Prenatal Injuries From Passive Tobacco Smoke: Establishing A Cause Of Action For Negligence, Julie E. Lippert

Kentucky Law Journal

No abstract provided.

Unavoidably Unsafe Products And Strict Products Liability: What Liability Rule Should Be Applied To The Sellers Of Pharmaceutical Products?, Richard C. Ausness

Law Faculty Scholarly Articles

Injuries from adverse drug reactions have increased dramatically in recent years. This increase is largely attributable to the changing nature of pharmaceutical products. First of all, more pharmaceutical products are currently available to physicians than ever in history. Presently, there are more than ten thousand prescription drugs on the market, and each year four hundred to five hundred new ones are introduced. Second, modern drugs often are more potent than their older counterparts, thus increasing the likelihood of adverse reactions.

It should come as no surprise that this rise in the number of drug-related injuries has led to a comparable …

Letter To Hazel Johnson Regarding A Proposed Seaall Brochure, November 30, 1989, Sue Burch

Correspondence

A letter from Sue Burch to Hazel Johnson enclosing an outline for a proposed SEAALL brochure.

Qualitative Metabolism Assessment Using High Performance Thin Layer Chromatography, Shih-Ling Chang

Veterinary Science Faculty Patents

A method for the qualitative assessment of oxidative drug metabolism deficiencies, preferably for the qualitative assessment of dextromethorphan metabolism, in a subject comprises analyzing a sample fluid from the subject, for example urine, which contains metabolites of a probe drug using high performance thin layer chromatography.

Law Enforcement And Engineering Incident Management—A Necessary Partnership: Incident Management, Jerry L. Lentz, James H. (Mike) Molloy, Sam W. Lester, Pat Dugger, William R. Monhollon, Robert L. Freeman, Mike Duncan

Kentucky's Annual Forum on Transportation

No abstract provided.

Letter To Dean Raymond Vondran Providing Information About Seaall, October 3, 1989, Sue Burch

Newsletter and Public Relations Committee

A letter from Sue Burch to Dean Raymond Vondran providing a correction to the letter dated September 12, 1989.

Letter To Dean Tom Waldhart Providing Information About Seaall, October 3, 1989, Sue Burch

Newsletter and Public Relations Committee

A letter from Sue Burch to Dean Tom Waldhart providing a correction to the letter dated September 12, 1989.

Method And Composition For Safely Delaying Parturition And Synchronizing Farrowing In Swine, Lee A. Edgerton, Bruce T. Eckerle

Animal and Food Sciences Faculty Patents

A method and composition are provided for extending the gestation period of a sow so as to increase the live birth and survival rates of a swine litter without adversely affecting the sow. The method includes the step of administering an effective dosage of estrogen to the sow 21/2-7 days prior to the end of the expected gestation period for the sow. The composition administered includes from 0.5-10 mg of an estrogen selected from a group consisting of estradiol benzoate, estradiol valerate, estrone, estradiol 17β and effective mixtures thereof. The composition is adapted for administration parenterally by including a carrier …

Letter To Dean Raymond Vondran Providing Information About Seaall, September 12, 1989, Sue Burch

Newsletter and Public Relations Committee

A letter from Sue Burch to Dean Raymond Vondran providing information on SEAALL to share with Library School students.

Letter To Dean Tom Waldhart Providing Information About Seaall, September 12, 1989, Sue Burch

Newsletter and Public Relations Committee

A letter from Sue Burch to Dean Tom Waldhart providing information on SEAALL to share with Library School students.

The Lexington Camera Club, 1936-1972, Robert C. May

The Kentucky Review

No abstract provided.

The Review, Spring 1989, University Of Kentucky College Of Law

Annual Magazines

No abstract provided.

New Opportunities For Science Students In Agronomy, Wilbur Frye

Soil Science News and Views

High school students interested in science and looking for a field of study that will prepare them for a rewarding career will like the proposed new agronomy programs. The Agronomy Department at the University of Kentucky is preparing to offer undergraduate students three future-oriented options--Plant and Soil Management, Plant Science, and Soil Science. In designing these options, we tried to determine what agronomy students need to be prepared to do in a rapidly changing and highly competitive world of the 1990s.

Isolation And Immunological Characterization Of A Group Of New B Lymphomas From Cba Mice, Venkatachalam Udhayakumar, Peter H. Brodeur, M. S. Rajagopalan, Stephen Zimmer, Karen E. Pollok, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

We have isolated and characterized a new series of B lymphomas which occurred spontaneously in a group of CBA N mice that were transferred with spleen or lymph node cells from 24-month-old CBA Ca mice. Tumor cell lines from six CBA N mice that received spleen cells were rescued and designated as BKS-2, BKS-3, BKS-4, BKS-5, BKS-6, and BKS-7. Also, tumor cells from a recipient of lymph node cells were rescued and the resulting cell line was designated BKL. These tumor cells expressed membrane immunoglobulin (μ,κ), major histocompatibility complex Class I and Class II molecules, B220, Lyb8, Fc receptors, J11d, …

Activated Carbon Filters, Joseph L. Taraba, Linda Heaton, Tom Ilvento

Agricultural Engineering Extension Updates

Many people feel the water supplied by public water systems to their home faucets is not safe. Most people judge the quality of their water by taste, odor and appearance. But the risk to one's health cannot be judged by these factors. Many of the chemicals or biological organisms that affect one's health are tasteless, odorless and cannot be seen. In searching for a means to improve the safety to their drinking water they encounter water filters, water purifiers, activated carbon (AC) filters that are common names for home drinking water treatment devices. In reading the labels, boxes and instructions …

Teratogenic Effects Of Zinc On Embryo-Larval Stages Of The Fathead Minnow (Pimephales Promelas), Barbara A. Ramey

KWRRI Research Reports

The effects of zinc on embryos and larvae of the fathead minnow (Pimephales promelas) were studied using standard 8-day embryo-larval bioassay techniques. The objective was to determine if there was a period in embryonic development which would be the most sensitive to the toxic and teratogenic effects of zinc. Five developmental stages were exposed to 0.5, 1.0 and 3.0 mg/L. After 96 hr, all animals exposed to 3.0 mg Zn/L were dead. The hatching stage was the most affected by 1.0 mg/L, with only 59% surviving after 96 hr, while the tailbud stage showed essentially control-level survival. However, virtually all …

The Effect Of Preozonation On The Anaerobic Biodegradability Of Resistant Phenolic Compounds, Yi-Tin Wang, Pin-Chieh Pai, James L. Latchew

KWRRI Research Reports

Ozone pretreatment studies of four model phenolic compounds were conducted to evaluate the effects of ozonation on the anaerobic biodegradability and toxicity of these compounds. Two types of batch studies, the Biochemical Methane Potential (BMP) and the Anaerobic Toxicity Assay (ATA), were performed on samples ozonated upon phenol, o-cresol, 2,5-dichlorophenol, and 2,4-dinitrophenol.

Experimental results showed that toxic and refractory phenolic compounds were converted to methane gas by means of preozonation. In general, the biodegradable fraction of the oxidation products increased as the ozone dose was increased. However, ozonation to achieve at least 60% COD reduction was necessary to faciliate methane …

Phloretin And Phlorizin Derivative Containing Compounds, Donald F. Diedrich, Susanne L. Diedrich

Pharmacology and Nutritional Sciences Faculty Patents

Compounds including phloretin and/or phlorizin derivatives coupled to an undigestible and non-absorbable matrix are provided. The compounds have pharmacological efficacies. They inhibit sugar uptake from the intestine and may be used in composition form in methods for treating diabetes and for promoting weight loss. A method for the manufacture of these compounds and a novel intermediate phlorizin derivative for making these compounds are also disclosed.

Woody Plants Under Stress, Deborah B. Hill, William M. Fountain

Agriculture and Natural Resources Publications

When people see their woody plants (shrubs and trees) decline, they often want a "magical" treatment to make them lush, green and healthy again. But no magic exists. This publication should help you understand some common causes of woody plant stress, how stress leads to decline and what measures, if any, can make the tree healthy again. Remember, however, that all trees and shrubs like every living organism, will eventually die.

Preparation Of Biodegradable Microspheres Useful As Carriers For Macromolecules, Patrick P. Deluca, Frantisek Rypacek

Pharmaceutical Sciences Faculty Patents

A method for preparing biodegradable microspheres having a three-dimensional network in which biologically active macromolecular agents are physically entrapped therein. The microsphere is able to degrade and release the macromolecular agent at a controlled rate. The method involves emulsifying a vinyl derivative of a biodegradable hydrophilic polymer, a water-soluble monovinyl monomer and a biologically active macromolecule in water, and copolymerizing the biodegradable hydrophilic polymer and the water-soluble monovinyl monomer such that the biologically active macromolecule is entrapped therein.