Digital Commons Network^™

Long-Term Evaluation Of The Use Of The Transdermal Contraceptive Patch In Adolescents, Stephanie Logsdon, Jessica Richards, Hatim A. Omar

Pediatrics Faculty Publications

The transdermal contraceptive patch, Ortho Evra™, was approved in December 2001 and released on the market in June 2002. In this study, we reviewed clinical data of young women who started the patch between June 2002 and December 2003 in the adolescent medicine clinic at a university-based outpatient center. A total of 62 patients started the patch in that period and two of them were lost to follow-up. Mean age of patients was 17.9 years and mean length of use was 10 cycles. Only 10 patients (16.7%) discontinued use. Reasons for discontinuation were moderate to severe skin irritation (3 patients, …

Clinical Profiles, Occurrence, And Management Of Adolescent Patients With Hair-An Syndrome, Hatim A. Omar, Stephanie Logsdon, Jessica Richards

Pediatrics Faculty Publications

The syndrome of hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) is a subphenotype of the polycystic ovary syndrome. It is one of the most common causes of menstrual problems, hyperandrogenic symptoms, and insulin resistance among young women. Review of clinical data in an outpatient adolescent clinic showed that of the 1,002 young women (ages 10-21 years) attending the clinic over a 2-year period, 50 (5%) were diagnosed with HAIR-AN syndrome. Mean age of the patients was 15.5, initial mean weight at diagnosis was 94.5 kg, and the mean BMI was 33.33 kg/m2. Patients were treated with a weight-stabilization and -reduction …

The New Promised Land: Black-White Convergence In The American South, 1940-2000, Jacob L. Vigdor

University of Kentucky Center for Poverty Research Discussion Paper Series

The black-white earnings gap has historically been larger in the South than in other regions of the United States. This paper shows that this regional gap has closed over time, and in fact reversed during the last decades of the twentieth century. Three proposed explanations for this trend focus on changing patterns of selective migration, reduced discrimination in Southern labor markets, and lower levels of school segregation and school resource disparities in the modern South relative to the North. Evidence suggests that reductions in Southern labor market discrimination explain rapid regional convergence in racial wage gaps between 1960 and 1980. …

Methods For Increasing Leptin Levels Using Nicotinic Acid Compounds, Elaine L. Jacobson, Myron Jacobson, Hyuntae Kim

Graduate Center for Nutritional Sciences Faculty Patents

The invention relates to the use of nicotinic acid and nicotinic acid esters, such as nicotinic acid alkyl esters, to increase the amount of leptin in a subject. As a result, one can treat conditions, such as conditions characterized by wounds, by administering sufficient amounts of nicotinic acid or nicotinic acid ester to increase leptin levels to alleviating amounts. Various conditions and modes of treatment are disclosed.

Forage News [2004-06], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• KFGC Field Day
• AFGC to Meet In Roanoke, Virginia June 12-16
• Forage Species and Spatial Effects on the Dietary Intake of Goats
• Kentucky Ranks High in Beef
• Forage-Animal Production Research Unit: Most Recent Agriculture Research Service Location
• Calibrating Seeders
• Upcoming Events

Methods To Impair Hematologic Cancer Progenitor Cells And Compounds Related Thereto, Craig Jordan

Internal Medicine Faculty Patents

Primitive or progenitor hematologic cancer cells have been implicated in the early stages and development of leukemia and malignant lymphoproliferative disorders, including acute myelogenous leukemia (AML), chronic myelogenous leukemia (CML) and chronic lymphoid leukemia (CLL). Interleukin-3 receptor alpha chain (IL-3Rα or CD123) is strongly expressed on progenitor hematologic cancer cells, but is virtually undetectable on normal bone marrow cells. The present invention provides methods of impairing progenitor hematologic cancer (e.g., leukemia and lymphomic) cells by selectively targeting cells expressing CD123. These methods are useful in the detection and treatment of leukemias and malignant lymphoproliferative disorders. Also provided are compounds useful …

Inhibitor Of Plant Peptide Deformylase For Use As Broad-Spectrum Herbicides And Method For Identifying The Same, Robert L. Houtz, Lynnette M. A. Dirk, Mark Allan Williams

Horticulture Faculty Patents

The invention relates to a method of identifying herbicides and to the use of inhibitors of plant peptide deformylase as broad spectrum herbicides.

Plant Trichome Gland Specific Promoter Sequence, George J. Wagner, Sushen Gan, Erming Wang, Rui Wang

Kentucky Tobacco Research and Development Center Faculty Patents

The present invention relates to a trichome specific regulatory sequence.

The Influence Of Environmental Temperature And Substrate Initial Moisture Content On Aspergillus Niger Growth And Phytase Production In Solid−State Cultivation, Seaborn B. Carter, Sue E. Nokes, Czarena L. Crofcheck

Biosystems and Agricultural Engineering Faculty Publications

Aspergillus niger is being used commercially for phytase production utilizing solid-state cultivation; however, no studies have been published that investigated the optimal environmental temperature and initial substrate water content to maximize fungal growth and/or phytase production. Solid-state cultivations of Aspergillus niger on wheat bran and soybean meal were conducted at three temperatures (25°C, 30°C, and 35°C) and three initial moisture contents (50%, 55%, and 60% wet basis) in a split-plot full-factorial experimental design. Fermentations were conducted for 0, 24, 48, 72, and 120 h. The containers were sampled destructively and assayed for phytase activity and glucosamine concentration as an estimate …

The Gaia Hypothesis And Ecofeminism: Culture, Reason, And Symbiosis, Serena Anderlini-D'Onofrio

disClosure: A Journal of Social Theory

No abstract provided.

Globalization, Or The Vanishing Present Of Postcolonialism? (And The Figuration Of The Comprador-Intellectuai), Saikat Majumdar

disClosure: A Journal of Social Theory

No abstract provided.

Method For Identifying Regulators Of Protein-Advanced Glycation End Product (Protein-Age) Formation, Elaine L. Jacobson, Myron Jacobson, Georg T. Wondrak

Graduate Center for Nutritional Sciences Faculty Patents

The invention relates to methods for identifying compounds which affect cellular stress. In particular, the method relates to identifying compounds which inhibit protein advanced glycation end product formation, where the compounds are carbonyl scavengers which inhibit the formation. The assay involves combing the substance of interest with histone H1 and ADP-ribose, and then measuring fluorescence and protein cross linking. Various inhibitors of protein AGE glycation have been identified, using this assay.

Forage News [2004-04], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Spring Grazing School – Final Call
• Forage Extension Website
• Dr. Mike Collins Accepts Position at Mississippi State University
• Mr. Allen Johnson Accepts Position with Montgomery County Regional Marketing Association
• Hay Contest Winners
• Rotational Grazing’s Efficient
• Emergence and Survival of Legumes Seeded into Pastures
• Does Fertilizer Harm Soil Microbes?
• Kentucky Farm Numbers
• Upcoming Events

Carbon Fiber For Air Filtration, Marit Jagtoyen, Francis J. Derbyshire, Rosemary Anne Alexander Derbyshire

Center for Applied Energy Research Faculty Patents

Described are filters containing free-activated carbon fibers or activated carbon fibers in the form of a composite used for filtering a variety of contaminants, including pathogens, from air. These filters can provide effective and efficient removal of contaminants from air, requiring only short contact time between the air being filtered and the filter itself, with only a minimum pressure drop across the filter. The characteristics of these filters allow for effective filtration with only thin filter layers being required. The process of filtering air utilizing these filters is also disclosed.

Moisture--Temperature Management During Alfalfa Hay And Silage Making & Storing, Michael Collins

Kentucky Alfalfa and Stored Forage Conference

In some areas of the country, producers store a substantial portion of their forage for winter feeding as silage or haylage. However, hay remains the most popular storage method for forage. Hay stores well for long periods and is better suited to cash sale and transportation than silage. Mechanical conditioning, which gained acceptance during the 1950's is probably still the greatest single change in hay harvesting and storage technology during this century. However, a number of other noteworthy changes and innovations have occurred in recent years which have helped to reduce the extent of losses during hay harvesting and storage.

Magnetoelastic Sensor For Characterizing Properties Of Thin-Film/Coatings, Leonidas G. Bachas, Gary Barrett, Craig A. Grimes, Dimitris Kouzoudis, Stephan Schmidt

Chemistry Faculty Patents

An apparatus for determining elasticity characteristics of a thin-film layer. The apparatus comprises a sensor element having a base magnetostrictive element at least one surface of which is at least partially coated with the thin-film layer. The thin-film layer may be of a variety of materials (having a synthetic and/or bio-component) in a state or form capable of being deposited, manually or otherwise, on the base element surface, such as by way of eye-dropper, melting, dripping, brushing, sputtering, spraying, etching, evaporation, dip-coating, laminating, etc. Among suitable thin-film layers for the sensor element of the invention are fluent bio-substances, thin-film deposits …

Substituted Pentacenes And Electronic Devices Made With Substituted Pentacenes, John E. Anthony, David L. Eaton, Sean Parkin

Chemistry Faculty Patents

Novel substituted pentacenes and electronic devices made with those substituted pentacenes are disclosed.

Using Covers To Minimize Odor And Gas Emissions From Manure Storages, José R. Bicudo, David R. Schmidt, Larry D. Jacobson

Agricultural Engineering Extension Publications

Odor emissions from animal production sites are typically the leading cause of nuisance complaints. Locating facilities far from neighbors is often a solution to the odor problem, but this is not always an option for producers. Most often, reducing odor emissions from the farm is the only option available.

Nucleic Acid Encoding Human Rev1 Protein, Zhigang Wang, Winston Lin, Hua Xin, Xiaohua Wu

Toxicology and Cancer Biology Faculty Patents

The present invention relates to a human cDNA homologous to the yeast REV1 gene. The sequence of human REV1 (hREV1) gene is described.

Getting More From Forages, Garry D. Lacefield

Forage Symposium at the Kentucky Cattlemen’s Convention

In human endeavors, results are usually highly correlated with investments in terms of thought, time, effort, and a certain amount of money. In particular, the best and most profitable forage programs have had the most thought put into them. Top producers strive to continue to improve their operations by developing strategies, practices, and procedures that will result in “GETTING MORE FROM FORAGES”.

Reflections On Undergraduate Research Mentoring, Robert L. Houtz

Kaleidoscope

No abstract provided.

Statistical Procedures For Evaluating Daily And Monthly Hydrologic Model Predictions, Marilyn E. Coffey, Stephen R. Workman, Joseph L. Taraba, Alex W. Fogle

Biosystems and Agricultural Engineering Faculty Publications

The overall study objective was to evaluate the applicability of different qualitative and quantitative methods for comparing daily and monthly SWAT computer model hydrologic streamflow predictions to observed data, and to recommend statistical methods for use in future model evaluations. Statistical methods were tested using daily streamflows and monthly equivalent runoff depths. The statistical techniques included linear regression, Nash-Sutcliffe efficiency, nonparametric tests, t-test, objective functions, autocorrelation, and cross-correlation. None of the methods specifically applied to the non-normal distribution and dependence between data points for the daily predicted and observed data. Of the tested methods, median objective functions, sign test, autocorrelation, …

Kentucky Water Resources Research Institute Annual Technical Report Fy 2003, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The FY2003 Annual Technical Report for Kentucky consolidates reporting requirements of the Section 104(b) base grant award in a single technical report that includes: 1) a synopsis of each research project supported during the period, 2) a list of related reports, 3) a description of information transfer activities, 4) a sumarry of student support during the reporting period, and 5) notable achievements and awards during the year.

Community Design Of A Light-Rail Transit Oriented Development Using Casewise Visual Evaluation (Cave), Keiron Bailey, Ted H. Grossardt

Kentucky Transportation Center Faculty and Researcher Publications

The Transit Authority of River City (TARC) is in the preliminary engineering phases of developing a light-rail transit system running from downtown Louisville, Kentucky to the city’s southern suburbs, a distance of approximately 15 miles. In collaboration with the research team, TARC wished to test an innovative methodology for improving community participation in the design of a light rail transit-oriented development for the Smoketown/Shelby Park area. The Smoketown/Shelby Park neighborhood is a low-income area located to the south of the University of Louisville Medical Center. A suitable site for the station has been identified by TARC and its design partners, …

The Importance Of Research In Undergraduate Education: The Impact Of The Beckman Scholars Program, Sylvia Daunert

Kaleidoscope

No abstract provided.

A Gc-Ms Method For The Determination Of Isoxsuprine In Biological Fluids Of The Horse Utilizing Electron Impact Ionization, Jeffrey M Bosken, A. F. Lehner, C. G. Hughes, W. E. Woods, F. C. Camargo, J. D. Harkins, J. Boyles, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Isoxsuprine is used to treat navicular disease and other lower-limb problems in the horse. Isoxsuprine is regulated as a class 4 compound by the Association of Racing Commissioners, International (ARCI) and, thus, requires regulatory monitoring. A gas chromatography-mass spectrometry method utilizing electron impact ionization was developed and validated for the quantitation of isoxsuprine in equine plasma or equine urine. The method utilized robotic solid-phase extraction and tri-methyl silyl ether products of derivatization. Products were bis-trimethylsilyl (TMS) isoxsuprine and tris-TMS ritodrine, which released intense quantifier ions m/z 178 for isoxsuprine and m/z 236 for ritodrine that were products of C-C cleavage. …

The Mare Reproductive Loss Syndrome And The Eastern Tent Caterpillar Ii: A Toxicokinetic/Clinical Evaluation And A Proposed Pathogenesis: Septic Penetrating Setae, Thomas Tobin, J. Daniel Harkins, John Ford Roberts, Patricia W. Vanmeter, Tara A. Fuller

Maxwell H. Gluck Equine Research Center Faculty Publications

Reviewing the mare reproductive loss syndrome (MRLS), it is proposed that the fundamental mechanism of this syndrome, which includes early fetal loss, late fetal loss, uveitis, pericarditis, and encephalitis, is tissue penetration by septic barbed setal fragments (septic penetrating setae) from Eastern tent caterpillars (Malacosoma americanum). Once ingested, these barbed setal fragments migrate through moving tissues, followed by rapid hematogenous spread of bacteria, bacterial emboli, and/or septic fragments of setae (septic penetrating setal emboli), collectively referred to as septic materials. Pathogenic bacteria, therefore, enter the horse as hitchhikers on or in the caterpillar setal fragments, and MRLS is caused by …

Proof Of Product Defect, David G. Owen

Kentucky Law Journal

No abstract provided.

The Virulence Of BlackthinkTm And How Its Threat Of Ostracism Shackles Those Deemed Not Black Enough, Kimberly Jade Norwood

Kentucky Law Journal

No abstract provided.

Fashioning Afrocuba: Fernando Ortiz And The Advent Of Afrocuban Studies, 1906-1957, Jeremy Leeds Cass

University of Kentucky Doctoral Dissertations

This study attempts to organize the conglomerate of writing on Africans within Republican Cuba. Starting with an examination of the scientific stages of such writing, we will trace the assorted work of Fernando Ortiz (1881-1969), whose anthropological study of Afrocuba produced myriad readings of the heritage. The multiplicity of renderings of Cuba s Africans from the scientific arena including condemning, racially charged treatises and spiritual conceptualizations of the richness of Cuba s African heritage generated an air of inconstancy. Indeed, the contradictions generated by the discipline s scientific course were incredibly polarized, representative of an ambiguity that became emblematic of …