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Cd(Ii)-, Pb(Ii)- And Hg(Ii)-2-Aminoethanethiolates, Mohan Singh Bharara

University of Kentucky Doctoral Dissertations

This theses presents the synthesis and characterization of Cd(II)-, Pb(II)- and Hg(II)-aminoethanethiolates in aqueous media. 2-Aminoethanethiolate, a versatile sulfur andnitrogen (S/N) based ligand was used due to its resemblance to the naturally occurringamino acid, cysteine. The work is presented in four major parts: first, backgroundinformation on the versatile structural chemistry of Cd, Pb and Hg-thiolates with S/Ncontaining ligands; second, synthesis and characterization of Cd(II) with 2-aminoethanethiolates; third, synthesis and characterization and structural chemistry ofPb(II) with 2-aminoethanethiolates; and fourth, synthesis and characterization of Hg(II)-2-aminoethanethiolates in solution- and solid-state with emphasis on the mechanisticpathways for the formation of clusters.The compounds reported here …

Intergenerational Communication About African American Women's Health: The Sharing Of Health Messages Between Diabetic Mothers And Their Non-Diabetic Adult Daughters, Angela F. Cooke-Jackson

University of Kentucky Doctoral Dissertations

The prevalence of type II diabetes is high among African-American women but research that emphasizes black mothers and their adult daughters is rarely studied in social sciences or communication research. Though existing research addresses various domains of the mother-daughter relationship scant information addresses the significance of talk or the transmission of health information between African-American diabetic mothers and their non-diabetic adult daughters. For that reason, this dissertation investigates information sharing among a sample of African-American mothers with type II diabetes and their non-diabetic adult daughters.This study's two primary research objectives were to: 1. describe whether and how African-American type II …

The Integration Of The Theory Of Planned Behavior, Altruism, And Self-Construal: Implications For Designing Recycling Campaigns In Individualistic And Collectivistic Societies, Rungrat Chaisamrej

University of Kentucky Doctoral Dissertations

This study was an effort to uncover four major facts: (a) the predictive power ofthe proposed integrated model, which posits the influence of attitudes (ATT), subjectivenorms (SN), perceived behavior control (PBC), altruism, self-construal, and paperrecyclingknowledge on behavioral intentions; (b) the moderating effects ofindividualism-collectivism (I-C) on the attitudes-intentions relationship and thesubjective norms-intentions relationship; (c) the comparison of the predictive power ofthe TPB model and the proposed integrated model; and (d) the relationship between twointentions measures: behavioral intentions and implementation intentions.This cross-sectional research consisted of two phases: the TPB elicitation researchand the main study. Participants were undergraduate students recruited from two majorpublic …

Suspended Sediment And Pathogen Transport In Two Inner Bluegrass Karst Ground-Water Basins, Woodford County, Kentucky, Thomas M. Reed

University of Kentucky Master's Theses

Multiple parameters were monitored during an 18-month period in two karst groundwater basins in Woodford County, Kentucky, in order to assess the effects of land use on water quality. Blue Hole Spring drains a primarily urban area, whereas spring SP-2 drains an agricultural area. Water-quality parameters were monitored manually weekly or biweekly, as well as more frequently during storms. Discharge (Q), temperature (T), specific conductance (SC), and turbidity were continuously monitored and logged at 15-minute intervals. It is hypothesized that pathogen and sediment concentrations would be lower at SP-2 than at Blue Hole Spring due to differences in land use …

Shear-Wave Velocities And Derivative Mapping For The Upper Mississippi Embayment, David M. Vance

University of Kentucky Master's Theses

During the past two decades, University of Kentucky researchers have been acquiring seismic refraction/reflection data, as well as seismic downhole data, for characterizing the seismic velocity models of the soil/sediment overburden in the central United States. The dataset includes densely spaced measurements for urban microzonation studies and coarsely spaced measurements for regional assessments. The 519 measurements and their derivative products often were not in an organized electronic form, however, limiting their accessibility for use by other researchers. In order to make these data more accessible, this project constructed a database using the ArcGIS 9.1 software. The data have been formatted …

Citizens On Patrol: Community Policing And The Territorialization Of Public Space In Seattle, Washington, Marcia Rae England

University of Kentucky Doctoral Dissertations

This dissertation shows how organizations, including local government and police, and residents within Seattle, Washingtons East Precinct define and police the contours of community, neighborhoods and public space. Under the rubric of public safety, these players create territorial geographies that seek to include only those who fit the narrowly conceived idea of a neighbor. Territoriality is exercised against the social Other in an attempt to build a cohesive community while at the same time excluding those who are seen as different or as non-conformant to acceptable behaviors in the neighborhood. This research provides a framework through which to examine how …

The Politics Of Garbage: Municipal Solid Waste In Oaxaca, Mexico, Sarah Anne Moore

University of Kentucky Master's Theses

This dissertation analyzes the politics of garbage in Oaxaca, Mexico. In particular, it explores the tactics used by a marginalized colonia near the dump to affect waste management and local development. This colonia provokes garbage crises by blocking the metropolitan areas access to its dump. As a result, garbage builds up in the city and public officials are forced to negotiate with colonia residents. I argue that two prior processes are essential to the success of this strategy. First, the mid-sized city in southern Mexico implemented many new waste management practices during the latter half of the 20th century and …

A Political Ecology Of The Chipko Movement, Sya Kedzior

University of Kentucky Master's Theses

The Indian Chipko movement is analyzed as a case study employing a geographically-informed political ecology approach. Political ecology as a framework for the study of environmental movements provides insight into the complex issues surrounding the structure of Indian society, with particular attention to its ecological and political dimensions. This framework, with its focus on social structure and ecology, is distinct from the more traditional approaches to the study of social movements, which tend to essentialize their purpose and membership, often by focusing on a single dimension of the movement and its context. Using Chipko as a case-study, the author demonstrates …

Design Of Partial Enclosures For Acoustical Applications, Amy Elizabeth Carter

University of Kentucky Master's Theses

Enclosures are a very common way to reduce noise emissions from machinery. However, enclosures display complex acoustic behavior that is difficult to predict. The research presented in this thesis uses the boundary element method in order to better understand the acoustic behavior of a partial enclosure. Insertion loss was used as the performance measure and the effect of several design factors on the overall insertion loss was documented. Results indicate that the most important factors affecting enclosure performance are the opening size, amount of absorption, and the source-to-opening distance.

Characterization And Measurement Of Tension-Induced Longitudinal Wrinkles In Gossamer Membranes Using Photogrammetry, Sreeram Mangalampalli

University of Kentucky Master's Theses

Gossamer membranes are large, ultra light weight, highly flexible thin films. They have been proposed for use as elements in systems such as solar sails and optical apertures, whose large areas require a low-mass material that can be launched in a compact package and then deployed to operational configuration upon reaching orbit. Many of the proposed applications require that the film possess a flat, wrinkle-free surface. Surface wrinkle configuration is determined, in part, by the method used to support the film. One configuration that has not been studied in detail involves the formation of vertical wrinkles oriented along the direction …

Heat Transfer And Chemical Processes In Chemical Vapor Deposition Reactor For Synthesis Of Carbon Nanotubes, Wahed Rezk Wasel

University of Kentucky Doctoral Dissertations

A small-scale model of a CVD reactor was built. Axial and radial of major species concentrations and temperature profiles were obtained with a micro gas chromatograph and a fine thermocouple. Those temperature and species concentrations revealed detailed thermal and chemical structures of the CVD reactor.

The concentrations of argon plus hydrogen, methane, and C₂H_x (C₂H₂ + C₂H₄ + C₂H₆) resulting from xylene decomposition were measured along the CVD at different temperatures. Ferrocene was added to xylene to investigate the effect of a catalyst on composition profiles. The …

Nonparametric Control Chart For The Range, Arnold J. Stromberg

Statistics Faculty Patents

A method is provided for detecting or predicting an undesired deviation in variability of at least one parameter being monitored, wherein the variation in the parameter is incrementally recorded. The method comprises establishing the number of subsets of a dataset that have a range of the difference between any two datapoints within the dataset, and computing a control chart for the range based thereon. The method accurately detects changes in variability in real time. The true distribution of the data is reflected, and the desired result is achieved without requiring an inordinate number of computations.

Disposal Of Bridge Paint Residue, Theodore Hopwood Ii, Sudhir Palle

Kentucky Transportation Center Research Report

Paint residue generated by bridge maintenance painting commonly contains lead requiring the residue to be disposed of as a hazardous waste. Several alternatives are being investigated in this study, chemical stabilization and recycling as options for the Kentucky Transportation Cabinet (KYTC) to consider in addressing the waste stream generated by bridge maintenance painting operations.

In the initial portion of this study, four chemical stabilization materials were identified as candidates for xperimental/demonstration projects entailing maintenance painting. A recycling option was also provided. An experimental bridge painting project was let by KYTC to investigate the use of two chemical stabilizers and the …

Pumping Or Mixing System Using A Levitating Magnetic Element, Aexandre N. Terentiev

Physics and Astronomy Faculty Patents

A system capable of pumping or mixing fluids using a rotating magnetic element or bearing levitated by a cold superconducting element is disclosed.

The Chemical Species Of Aluminum Influences Its Paracellular Flux Across And Uptake Into Caco-2 Cells, A Model Of Gastrointestinal Absorption, Yuzhao Zhou, Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

Aluminum (Al) can cause neurotoxicity, a low-turnover osteomalacia, and microcytic anemia. To test the null hypothesis that the chemical form (species) of Al does not influence its mechanism or rate of absorption from the gastrointestinal tract, Al flux across and uptake into Caco-2 cells was investigated. Caco-2 cells were grown on porous membranes mounted in vertical diffusion chambers or in 35-mm-diameter plastic cell culture dishes. When 8 mM ²⁷Al was introduced as the ion, citrate, maltolate, fluoride, or hydroxide, the apical to basolateral apparent permeability (P_app) of Al correlated highly with the P_app of lucifer yellow …

Cpg Oligodeoxynucleotides Stimulate Cord Blood Mononuclear Cells To Produce Immunoglobulins., Cheri D Landers, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

CpG oligodeoxynucleotides (ODNs) stimulate adult B cells leading to cellular proliferation and immunoglobulin production. It is unknown if CpG-ODNs similarly stimulate neonatal human B cells. Neonates have immature immune responses and are poorly responsive to thymus independent antigens such as polysaccharides. We determined umbilical cord cells' response to CpG-ODNs. Adult and umbilical cord B cells produced similar amounts of IgM (adult 1371 +/- 352 vs. cord 1873 +/- 1084 ng/ml) in response to CpG-ODN stimulation. Although CpG-ODN was able to stimulate adult IgG and IgA production, cord cells produced less IgG (153 +/- 58 vs. 10 +/- 2.5 ng/ml) and …

Effects Of Commercial Diazinon And Imidacloprid On Microbial Urease Activity In Soil And Sod, C. W. Ingram, Mark S. Coyne, David W. Williams

Plant and Soil Sciences Faculty Publications

Diazinon [O,O-diethyl O-2-isopropyl-6-methyl(pyrimidine-4-yl) phosphorothioate] and imidacloprid [1-(1-[6-chloro-3-pyridinyl]methyl)-N-nitro-2-imidazolidinimine] are applied to lawns for insect control simultaneously with nitrogenous fertilizers such as urea, but their potential effect on urease activity and nitrogen availability in turfgrass management has not been evaluated. Urease activity in enzyme assays, washed cell assays, and soil slurries was examined as a function of insecticide concentration. Intact cores from field sites were used to assess the effect of insecticide application on urease activity in creeping bentgrass (Agrostis palustris Huds.) and bluegrass (Poa pratensis L.) sod. Bacterial urease fromBacillus pasteurii and plant …

C-Jun N-Terminal Kinase (Jnk) Is Required For Survival And Proliferation Of B-Lymphoma Cells, Murali Gururajan, Roger Chui, Anbu K. Karuppannan, Jiyuan Ke, C. Darrell Jennings, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Several primary murine and human B lymphomas and cell lines were found to constitutively express high levels of the activated form of c-jun N-terminal kinase (JNK), a member of the mitogen-activated protein (MAP) kinase family. Proliferation of murine B lymphomas CH31, CH12.Lx, BKS-2, and WEHI-231 and the human B lymphomas BJAB, RAMOS, RAJI, OCI-Ly7, and OCI-Ly10 was strongly inhibited by SP600125, an anthrapyrazolone inhibitor of JNK, in a dose-dependent manner. The lymphoma cells underwent apoptosis and arrested at the G2/M phase of cell cycle. Furthermore, JNK-specific small interfering RNA (siRNA) inhibited the growth of both murine and human B lymphomas. …

Expression Of Cd68 And Macrophage Chemoattractant Protein-1 Genes In Human Adipose And Muscle Tissues: Association With Cytokine Expression, Insulin Resistance, And Reduction By Pioglitazone, Gina B. Di Gregorio, Aiwei Yao-Borengasser, Neda Rasouli, Vijayalakshmi Varma, Tong Lu, Leslie M. Milrd, Gouri Ranganathan, Charlotte A. Peterson, Robert E. Mcgehee Jr., Philip A. Kern

Clinical and Translational Science Faculty Publications

To examine the role of adipose-resident macrophages in insulin resistance, we examined the gene expression of CD68, a macrophage marker, along with macrophage chemoattractant protein-1 (MCP-1) in human subcutaneous adipose tissue using real-time RT-PCR. Both CD68 and MCP-1 mRNAs were expressed in human adipose tissue, primarily in the stromal vascular fraction. When measured in the adipose tissue from subjects with normal glucose tolerance, covering a wide range of BMI (21-51 kg/m²) and insulin sensitivity (S_I) (0.6-8.0 × 10^-4 min^-1 · μU^-1 · ml^-1), CD68 mRNA abundance, which correlated with the number …

[Review Of] Amg All-Music Guide, Robert A. Aken

Library Faculty and Staff Publications

No abstract provided.

Evaluation Of Kentucky’S “Buckle Up Kentucky: It’S The Law & It’S Enforced” 2005 Campaign, Kenneth R. Agent, Eric R. Green, Ronald E. Langley

Kentucky Transportation Center Research Report

The objective of this report was to document the results of the “Buckle Up Kentucky: It’s the Law & It’s Enforced” 2005 campaign in Kentucky. The campaign involved a combination of earned media, paid media, and enforcement. The earned media started two weeks prior to Memorial Day 2005and continued through the enforcement period. Two separate paid media campaigns were conducted.One dealt specifically with pickups while the other was a general campaign for all drivers. The pickup campaign started four weeks prior to Memorial Day and lasted two weeks. The general campaign was for the two weeks prior to Memorial Day. …

Avoiding Versus Seeking: The Relationship Of Information Seeking To Avoidance, Blunting, Coping, Dissonance, And Related Concepts, Donald O. Case, James E. Andrews, J. David Johnson, Suzanne L. Allard

Information Science Faculty Publications

QUESTION: How have theorists and empirical researchers treated the human tendency to avoid discomforting information?

DATA SOURCES: A historical review (1890-2004) of theory literature in communication and information studies, coupled with searches of recent studies on uptake of genetic testing and on coping strategies of cancer patients, was performed.

STUDY SELECTION: The authors' review of the recent literature included searches of the MEDLINE, PsychInfo, and CINAHL databases between 1992 and summer of 2004 and selective, manual searches of earlier literature. Search strategies included the following subject headings and key words: MeSH headings: Genetic Screening/psychology, Decision Making, Neoplasms/diagnosis/genetics/psychology; CINAHL headings: Genetic …

A Model Program For Youth Suicide Prevention, Hatim A. Omar

Pediatrics Faculty Publications

Youth suicide continues to be one of the leading causes of death in the United States. Nation wide it is the third leading cause of death in the 10-24 year old age group. The rate of suicide varies somewhat from state to state. In the state of Kentucky, youth suicide is the second leading cause of death. This article describes a grass root, community-based program for youth suicide prevention and its impact on the community. The Stop Youth Suicide Campaign was launched in October 2000 and included more than 30 local agencies. This program worked. through public education, education of …

Intention To Seek Information On Cancer Genetics, James E. Andrews, J. David Johnson, Donald O. Case, Suzanne L. Allard, Kimberly Kelly

Communication Faculty Publications

Objective. The public has a high interest in seeking personal genetic information, which holds implications for health information seeking research and health care policy. Rapid advances in cancer genetics research promise early detection, prevention and treatment, yet consumers may have greater difficulty finding and using the information they may need to make informed decisions regarding their personal health and the future of their families.

Design. A statewide telephone survey was conducted of non-institutionalized Kentucky residents 18 years of age or older to investigate factors associated with the intention to seek cancer genetics information, including the need for such information seeking …

Gonadal Steroids Differentially Modulate Neurotoxicity Of Hiv And Cocaine: Testosterone And Ici 182,780 Sensitive Mechanism, Sherie L. Kendall, Caroline F. Anderson, Avindra Nath, Jadwiga Turchan-Cholewo, Cantey L. Land, Charles F. Mactutus, Rosemarie M. Booze

Behavioral Science Faculty Publications

BACKGROUND: HIV Associated Dementia (HAD) is a common complication of human immunodeficiency virus (HIV) infection that erodes the quality of life for patients and burdens health care providers. Intravenous drug use is a major route of HIV transmission, and drug use is associated with increased HAD. Specific proteins released as a consequence of HIV infection (e.g., gp120, the HIV envelope protein and Tat, the nuclear transactivating protein) have been implicated in the pathogenesis of HAD. In primary cultures of human fetal brain tissue, subtoxic doses of gp120 and Tat are capable of interacting with a physiologically relevant dose of cocaine, …

Manganese Distribution Across The Blood-Brain Barrier. Iv. Evidence For Brain Influx Through Store-Operated Calcium Channels, Janelle S. Crossgrove, Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

Manganese (Mn) is a required co-factor for many ubiquitous enzymes; however, chronic Mn overexposure can cause manganism, a parkinsonian-like syndrome. Previous studies showed Mn influx into brain is carrier-mediated, though the putative carrier(s) were not established. Studies conducted with cultured bovine brain microvascular endothelial cells (bBMECs), which comprise the blood–brain barrier, revealed ⁵⁴Mn (II) uptake positively correlated with pH, was temperature-dependent, and was sodium- and energy-independent. Brain ⁵⁴Mn uptake correlated inversely with calcium (Ca) concentration, but ⁴⁵Ca uptake was unaltered by high Mn concentration. Lanthanum (La), a non-selective inhibitor of several Ca channel types, as well as …

Evaluation Of Methods To Limit The Time Taken To Investigate Crash Sites, Jennifer R. Walton, Monica L. Barrett, Kenneth R. Agent

Kentucky Transportation Center Research Report

Highway crashes have significant direct and indirect costs associated with them. Substantial sources of indirect costs are the congestion and delays that result from lane blockages or road closures while the crash is being investigated and the site cleared. In many cases, vehicles could be moved and roadways reopened very quickly, but this does not occur because of the need (or perceived need) to conduct a detailed investigation of the crash scene. The objective of this study was to identify opportunities to reduce the time required to investigate and clear crash scenes. This project includes a review of state and …

Bearing Capacity Analysis And Design Of Highway Base Materials Reinforced With Geofabrics, Tommy C. Hopkins, Liecheng Sun, Mikhail E. Slepak

Kentucky Transportation Center Research Report

The primary objective of this study was to develop and implement mathematical bearing capacity models originally proposed by Hopkins (1988, 1991) and Slepak and Hopkins (1993; 1995). These advanced models, which are based on limit equilibrium and are operated together, can be used to analyze the bearing capacity, or stability, of early construction of loads on a single layer of material, two-layered problems involving a layer of base aggregate and subgrade, and a foundation involving multiple layers of different materials, such as a flexible asphalt pavement. A Prandlt-type shear surface is used in the model analyses of layered foundations. In …

Permeability Of Corn, Soybeans, And Soft Red And White Winter Wheat As Affected By Bulk Density, Michael D. Montross, Samuel G. Mcneill

Biosystems and Agricultural Engineering Faculty Publications

Darcy’s law is a function of viscosity, permeability, and velocity and can be used to predict the airflow resistance in granular materials at low air velocities. Permeability also governs the magnitude of natural convection currents during periods of non-aerated grain storage. The permeability of corn, soybeans, soft white winter wheat, and soft red winter wheat were measured as a function of bulk density and moisture content. Air was passed through a column of grain and the flow rate and pressure drop measured. Bulk density and kernel density were also measured to determine the porosity of grain in the test column. …

Effect Of Fat And Casein Particles In Milk On The Scattering Of Elliptically Polarized Light, Czarena L. Crofcheck, Jeremie Wade, Janakiraman N. Swamy, Mustafa M. Aslan, M. Pinar Mengüç

Biosystems and Agricultural Engineering Faculty Publications

In this article, we present an experimental approach to determine the milk fat content using scattered light intensity profiles. The elements of the scattering (Mueller) matrix have been shown to provide valuable information about variation of the optical properties of scattering particles. The scattering behavior of fat and casein in terms of the scattering matrix elements was experimentally determined for milk with varying fat levels ranging from 0.05 wt% (skim) to 3.20 wt% (whole). Three of the scattering Mueller matrix elements, specifically S₁₁, S₁₂/S₁₁, and S₃₃/S₁₁, were found to be …