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Articles 61 - 90 of 7052
Full-Text Articles in Entire DC Network
Happy Belated Iep: How A Notice Of Procedural Safeguards Fails Children With Specific Learning Disabilities, Chrystal Clodomir
Happy Belated Iep: How A Notice Of Procedural Safeguards Fails Children With Specific Learning Disabilities, Chrystal Clodomir
Kentucky Law Journal
No abstract provided.
Dred Scott, Military Enslavement, And The Case For Reparations, Hugh Mcclean
Dred Scott, Military Enslavement, And The Case For Reparations, Hugh Mcclean
Kentucky Law Journal
No abstract provided.
Campus Coverage: How Biden's Title Ix Regulations Threaten Free Speech, Academic Freedom, And University Liability, Alex Drury
Kentucky Law Journal
No abstract provided.
Reaching For Starz: The Negative Impact Of Creating Limitations On Damages In Timely Copyright Claims, Lindley Williams
Reaching For Starz: The Negative Impact Of Creating Limitations On Damages In Timely Copyright Claims, Lindley Williams
Kentucky Law Journal
No abstract provided.
Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss
Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss
Progress in Scale Modeling, an International Journal
The phenomenon of Taylor or shear-induced dispersion of a non-passive scalar field in a pulsatile pipe flow is investigated, accounting for the scalar field's influence on fluid density and transport coefficients. By employing multiple scale analysis, an effective one-dimensional, unsteady mixing problem for the scalar field is obtained, which includes the diffusion coefficient for shear-induced dispersion. The resulting governing equations are applicable to a range of scalar transport problems in pulsatile pipe flows.
Renin-Angiotensin-Aldosterone System In Preeclampsia: Pathophysiological Insights And Links To Vascular Dementia, Robin C. Finch, Jenny Lutshumba, Elizabeth Mirsky, Esther Ndashaala, Kelsey Bullens, Emma Smith
Renin-Angiotensin-Aldosterone System In Preeclampsia: Pathophysiological Insights And Links To Vascular Dementia, Robin C. Finch, Jenny Lutshumba, Elizabeth Mirsky, Esther Ndashaala, Kelsey Bullens, Emma Smith
Pediatrics Faculty Publications
Pre-eclampsia, a condition characterized by new-onset hypertension during pregnancy and one or more indices of organ damage, is a major driver of both short and long-term maternal health outcomes. Individuals with a history of pre-eclampsia are at increased risk for cardiovascular, renal, and other chronic diseases. Recent studies have linked pre-eclampsia history with increased risk of dementia later in life, underscoring the importance of new guidelines emphasizing blood pressure control to reduce the risk of cognitive decline. Unfortunately, neither mechanisms underlying causes of pre-eclampsia nor their links with cognitive function are well understood. Vascular contributions to cognitive impairment and dementia …
Osimertinib Activates A Tgf-Β2-Dependent Secretory Program That Drives Lung Adenocarcinoma Progression, Madhurima Ghosh, Chao Wu, Abhishek Kumar, Monique Nilsson, John V. Heymach, Weina Zhao, Jiang Yu, Xin Liu, Na Ding, Shike Wang, Guan Yu Xiao, Angelo Chen, Kate Grimley, William K. Russell, Chad J. Creighton, Xiaochao Tan, Jonathan M. Kurie
Osimertinib Activates A Tgf-Β2-Dependent Secretory Program That Drives Lung Adenocarcinoma Progression, Madhurima Ghosh, Chao Wu, Abhishek Kumar, Monique Nilsson, John V. Heymach, Weina Zhao, Jiang Yu, Xin Liu, Na Ding, Shike Wang, Guan Yu Xiao, Angelo Chen, Kate Grimley, William K. Russell, Chad J. Creighton, Xiaochao Tan, Jonathan M. Kurie
Markey Cancer Center Faculty Publications
EGFR-mutant lung adenocarcinomas (LUADs) that are vulnerable to the EGFR antagonist osimertinib (Osi) eventually relapse, owing in part to the emergence of drug-tolerant persister (DTP) cells that arise through epigenetic mechanisms. Intratumoral DTP cells can herald a worse clinical outcome, but the way in which DTP cells influence LUAD progression remains unclear. Osi-resistant (OR) cells exhibit typical DTP cell features, including a propensity to undergo senescence and epithelial-mesenchymal transition (EMT), which can activate heightened secretory states. Therefore, we postulated that OR cells influence LUAD progression through paracrine mechanisms. To test this hypothesis, we utilized congenic pairs of EGFR-mutant LUAD cell …
High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann
High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann
Physiology Faculty Publications
Genetic diseases such as ion channelopathies substantially burden human health. Existing treatments are limited and not genotype specific. Here, we report a 2-step high-throughput approach to rapidly identify drug candidates for repurposing as genotype-specific therapy. We first screened 1,680 medicines using a thallium-flux trafficking assay against Kv11.1 gene variants causing long QT syndrome (LQTS), an ion channelopathy associated with fatal cardiac arrhythmia. We identified evacetrapib as a suitable drug candidate that improves membrane trafficking and activates channels. We then used deep mutational scanning to prospectively identify all Kv11.1 missense variants in an LQTS hotspot region responsive to treatment with evacetrapib. …
Sustained Increase In Extracellular Atp In The Lung Induced By Chronic Inhalation Exposure To Nitrogen Dioxide, Nai Ju Chan, Yueh Yin Chen, Chun Chun Hsu, You Shuei Lin, Maxwell Zakeri, Mehdi Khosravi, Lu Yuan Lee
Sustained Increase In Extracellular Atp In The Lung Induced By Chronic Inhalation Exposure To Nitrogen Dioxide, Nai Ju Chan, Yueh Yin Chen, Chun Chun Hsu, You Shuei Lin, Maxwell Zakeri, Mehdi Khosravi, Lu Yuan Lee
Physiology Faculty Publications
Nitrogen dioxide (NO2) is an environmental air pollutant and a potent oxidant. Epidemiological studies have revealed a close association between chronic cough and long-term inhalation exposure to NO2. ATP can be released from airway/lung epithelial cells upon inhalation exposure to oxidants, and convincing evidence established in recent clinical studies indicated that extracellular ATP in the respiratory tract plays an important role in the pathogenesis of refractory chronic cough. However, whether inhalation exposure to NO2 elevates the ATP release in the lung is not yet known. Results of this study showed: 1) in awake rats, acute …
Leadership And Creative Placemaking In Central Appalachia: Morehead, Kentucky, Toni C. Hobbs
Leadership And Creative Placemaking In Central Appalachia: Morehead, Kentucky, Toni C. Hobbs
Theses and Dissertations--Arts Administration
In rural Appalachia, longstanding patterns of extractive economic development, coupled with limited public investment and uneven institutional support, have contributed to persistent economic stagnation and a diminished sense of pride among residents. These conditions reflect deeper structural challenges, including economies shaped by resource extraction and external control. Addressing these conditions is critical to fostering economic growth, promoting cultural heritage, and enhancing overall well-being in the region. By cultivating resilient communities, leaders can create environments in which both the economy and local pride can thrive, contributing to a more prosperous and unified Appalachian region.
This study investigates the organizational and leadership …
Consumer Perceptions Of Farmers Market Performance: A Comparative Analysis Across States And Age Groups, Azita Varziri, Timothy A. Woods, Shuoli Zhao
Consumer Perceptions Of Farmers Market Performance: A Comparative Analysis Across States And Age Groups, Azita Varziri, Timothy A. Woods, Shuoli Zhao
Agricultural Economics Faculty Publications
The USDA Agricultural Marketing Service has invested in direct-to-consumer initiatives to expand local food consumption and enhance farmers market opportunities. To evaluate the effectiveness of these efforts, this study employs a sample-selected ordered probit model to analyze consumer perceptions of farmers market performance across four states in the Southeast United States. Specifically, we examine differences in awareness and performance of product quality, diversity, and market infrastructure. Awareness and perceptions vary significantly by age, other demographics, and state. These insights provide market organizers and policymakers with data-driven strategies to tailor marketing efforts and improve engagement across diverse consumer segments.
Philsongs: A Study Of Campfire Music Performed At Scouting America’S Philmont Scout Ranch (2014 To 2021), Ellyn Rager
Philsongs: A Study Of Campfire Music Performed At Scouting America’S Philmont Scout Ranch (2014 To 2021), Ellyn Rager
Theses and Dissertations--Music
This dissertation focuses on Philmont Scout Ranch, a national Scouting America high adventure base in New Mexico and the largest youth camp in the world, arguing that music at Philmont serves as a cultural force that fosters an intensive communal bond among staff and campers by blending participatory and presentational music-making practices, while producing and reinforcing memories of Philmont through interpretive performances that negotiate the place’s historical narratives. Using surveys, interviews, and Thomas Turino’s framework of participatory and presentational music-making to interpret the author’s 100 hours of field recordings, this study examines aspects of Philmont’s musical habits between 2014 and …
From Financial Education To Financial Decisions: Evidence On College Financing, Personal Finance Behavior, And Student Attitudes, Dongwei Shi
University of Kentucky Doctoral Dissertations
I examine how financial education shapes students’ financial knowledge, college financing decisions, and longer-term financial behavior.
The first chapter studies whether taking high school financial education in Kentucky affects students’ college financing decisions using linked administrative records on high school course-taking and postsecondary financial aid. Using school-level financial education course availability as an instrument, the chapter evaluates whether exposure to financial education is associated with differences in student loan borrowing and receipt of need-based aid.
The second chapter examines whether exposure to state high school financial education mandates improves financial literacy and longer-term personal finance behavior among U.S. adults. Using …
Forage News [2026-02], University Of Kentucky
Forage News [2026-03], University Of Kentucky
Localized Periodontitis In Young Individuals: Aggregatibacter Jp2 Clone, Immunological Dysfunctions And Other Stories, Luigi Nibali, Meaad M. Alamri, Manuela Maria Viana Miguel, Luciana M. Shaddox
Localized Periodontitis In Young Individuals: Aggregatibacter Jp2 Clone, Immunological Dysfunctions And Other Stories, Luigi Nibali, Meaad M. Alamri, Manuela Maria Viana Miguel, Luciana M. Shaddox
Oral Health Science Faculty Publications
Grade C molar-incisor pattern periodontitis (C-MIP) is the latest in a series of names given to a unique phenotype, characterized by an aggressive and rapid loss of tooth-supporting structures, starting early in life and usually affecting first molars and incisors. Although much less prevalent than the more generalized “chronic” forms of this disease in adults, it affects mostly young individuals of lower socioeconomic status and African descent, or from mixed-race populations, and shows a strong familial aggregation, pointing to a possible genetic contribution, yet not fully elucidated. Even though most of the studies report this disease in adolescents/young adults, it …
Integrated Management Of Diplodia Ear Rot And A Comparison Of Stenocarpella Species Affecting Corn, Luke C. Warner
Integrated Management Of Diplodia Ear Rot And A Comparison Of Stenocarpella Species Affecting Corn, Luke C. Warner
Theses and Dissertations--Plant Pathology
Corn is a globally important crop used for food, feed, and ethanol production, but often the grain quality is threatened by Diplodia ear rot, caused by Stenocarpella maydis and Stenocarpella macrospora. Effective management of Diplodia ear rot is difficult to achieve. This study evaluated the efficacy of foliar fungicides, including products listed by the Organic Material Research Institute (OMRI), against S. maydis in vitro and in field settings, as well as comparingthe aggressiveness of the two causal pathogens of Diplodia ear rot. The in vitro assays indicated a wide variation in sensitivity of S. maydis to the fungicide active ingredients, …
Chinese Lesbian, Gay, And Bisexual Positive Identity Measure (C-Lgb-Pim), Yawen Yang, Ellen D. B. Riggle, Fang Wang, Mengyan Wu, Ye Sun, Huilan Liu, Lisha Dai
Chinese Lesbian, Gay, And Bisexual Positive Identity Measure (C-Lgb-Pim), Yawen Yang, Ellen D. B. Riggle, Fang Wang, Mengyan Wu, Ye Sun, Huilan Liu, Lisha Dai
Gender and Women's Studies Faculty Publications
To support research and interventions using a positive, strength-based framework of lesbian, gay, and bisexual (LGB) identities in China, this study translates the Lesbian, Gay, and Bisexual Positive Identity Measure (LGB-PIM) into Standard Chinese and evaluating its reliability and validity among Chinese sexual minorities. Following Brislin’s standardized translation procedures (translation, back-translation, cultural adaptation, and pretesting), the scale retained 25 items across 5 dimensions. A convenience sample of 392 participants underwent assessments of internal consistency (α = 0.92), retest reliability (α = 0.80), structural validity (68.54% variance explained), and construct validity. The five-dimensional structure showed robust convergent validity (AVE > 0.50, CR …
Culturally Sustaining Pedagogy Through Popular Music And Media In Elementary Music Education, Martina Vasil
Culturally Sustaining Pedagogy Through Popular Music And Media In Elementary Music Education, Martina Vasil
Music Faculty Publications
Elementary music teachers in the United States face many challenges today, including an increasing cultural divide between teachers and students, worsening student behavior, and excessive exposure to technology in children’s lives. These challenges are magnified due to the hundreds of students elementary music teachers see weekly, the lack of teaching and planning time, and inadequate teaching resources, making it difficult to fully understand the culture and learning needs of every child. However, music educators may find culturally sustaining pedagogy (CSP) a useful tool for meeting the needs of a diverse student body. Further, when teachers engage in kid culture, the …
Building The Ryan White Hiv/Aids Program Bench In Kentucky, Lauren Bifulco, Kathleen Harding, Jana Collins, Anna Rogers, Lenon Farkash, Marwan Haddad, Alice Thornton
Building The Ryan White Hiv/Aids Program Bench In Kentucky, Lauren Bifulco, Kathleen Harding, Jana Collins, Anna Rogers, Lenon Farkash, Marwan Haddad, Alice Thornton
Epidemiology and Environmental Health Faculty Publications
The Ryan White HIV/AIDS program (RWHAP) is governed by legislative and programmatic guidelines that ensure comprehensive services are provided to persons with HIV (PWH) across the United States. Comprehensive training and skill building opportunities for programmatic staff are rare. RWHAP funding recipient organizations may struggle to acquire and retain essential program-specific knowledge, with downstream impact on patient care and treatment. We designed a comprehensive 11-session videoconference learning series to improve program staff’s confidence and competence with RWHAP fundamentals. Quantitative pre-vs-post session data were analyzed using Wilcoxon Signed-Rank tests, and qualitative data using thematic analysis. We enrolled 136 staff from 23 …
Economic Exchange And Relational Work In Doubled-Up Households, Hope Harvey
Economic Exchange And Relational Work In Doubled-Up Households, Hope Harvey
Sociology Faculty Publications
Doubling up, or sharing a home, is an increasingly common way that families make ends meet. Drawing on over 170 in-depth interviews with 60 parents, I ask how doubled-up household members understand and contest their economic relationships. I show that the success of intra-household economic exchange depends not only on the amounts exchanged, but also the shared meanings behind these exchanges. Given the lack of institutionalized expectations guiding doubled-up household relationships, household members draw on competing norms, framing the household as either a solidarity unit or a series of independent nuclear family units. Although disagreement over economic relationships is common, …
Perceived Adolescent Insecure Attachment With Mothers And Fathers, Helena Pipová, Martin Dolejš, Jaroslava Suchá, Alexander T. Vazsonyi
Perceived Adolescent Insecure Attachment With Mothers And Fathers, Helena Pipová, Martin Dolejš, Jaroslava Suchá, Alexander T. Vazsonyi
Sociology Faculty Publications
The aim of this study was to test relationships between adolescent insecure attachment (anxious and avoidant) with mothers and fathers and three outcomes: food addiction, eating disorders, and weight status, in a large multi-regional sample of Czech adolescents. Anonymous, self-reported data were collected from 3,677 adolescents (1,688 boys, 45.9% and 1,989 girls, 54.1%). Both anxious and avoidant attachment with mothers were positively associated with food addiction (p <.001) and eating-disorder risk (p <.001). Importantly, avoidant attachment with fathers uniquely and additively explained variance in both food addiction (p <.001) and eating-disorder risk (p =.003), after controlling for maternal attachment. Weight status was unrelated to attachment and was predicted by sex and parental education only. Study findings highlight the salience of insecure attachment with both mothers and fathers for food addiction and eating disorders among adolescents and identify the parental relationship as a key potential preventative strategy.
“Policymakers Need To See This!”, Ramona G. Olvera, Peter Balvanz, Owusua Yamoah, Kesla Klingler, Marisa D. Booty, Sylvia A. Ellison, Amy Farmer, Amy K. Kuntz, Hilary L. Surratt, Carrie B. Oser, Margaret L. Mcgladrey
“Policymakers Need To See This!”, Ramona G. Olvera, Peter Balvanz, Owusua Yamoah, Kesla Klingler, Marisa D. Booty, Sylvia A. Ellison, Amy Farmer, Amy K. Kuntz, Hilary L. Surratt, Carrie B. Oser, Margaret L. Mcgladrey
Sociology Faculty Publications
The use of Photovoice methods to identify and address public health challenges has evolved since this participatory action research method’s inception in the 1990s. However, there is a notable lack of research on the dissemination of Photovoice findings to promote community action and change. This study evaluates audience and Photovoice participants’ experiences of dissemination events presenting the results of 21 Photovoice projects that supplemented the HEALing Communities Study (HCS), a multistate community-based study of strategies to reduce opioid overdose deaths. The Photovoice projects captured the perspectives of people with lived experience of substance use disorder and front-line providers regarding their …
The Digital In The Library: Finding The Mutually Beneficial Synergy, James M. Donovan
The Digital In The Library: Finding The Mutually Beneficial Synergy, James M. Donovan
Law Faculty Books and Chapters
With the value of access to digital resources abundantly demonstrated during the COVID-19 lockdown, enthusiasm for the format is reaching new heights. This chapter counsels restraint, rebutting the argument that skepticism concerning the wide adoption of digital materials into the library is due merely to nostalgia by anti-technologists for a now-bygone age. Despite their obvious usefulness in certain situations, patrons have not responded well when libraries propose to discard legacy print collections in favor of transient electronic formats.To explain this rejection, this chapter argues that libraries are built upon principles of collection development and organization of materials in order to …
College Student Perceptions Of A Pilot Cooking And Nutrition Education Workshop Through The Lens Of The Social Cognitive Theory: A Qualitative Study, Emma Watras, Amelia Sullivan, Emalee Harrington, Mona Therrien-Genes, Kathryn Yerxa, Makenzie Barr-Porter, Jade Mcnamara
College Student Perceptions Of A Pilot Cooking And Nutrition Education Workshop Through The Lens Of The Social Cognitive Theory: A Qualitative Study, Emma Watras, Amelia Sullivan, Emalee Harrington, Mona Therrien-Genes, Kathryn Yerxa, Makenzie Barr-Porter, Jade Mcnamara
Dietetics and Human Nutrition Faculty Publications
This study qualitatively examined college students' perceptions of a pilot cooking and nutrition workshop, College Cooking Connection (CCC), through the Social Cognitive Theory (SCT) framework. Undergraduate students who attended at least one CCC workshop (N = 29) were invited to a 30 min virtual focus group. A trained moderator guided the discussion to gather perceptions of the program. Themes were identified using thematic analysis with a directive and deductive approach based on SCT. Focus groups revealed eight major themes across the SCT. Cognitive themes included: (1) improved nutrition literacy, (2) understanding the nutrition-mental health connection, and (3) increased awareness of …
Do Magnesium Ions Have Similar Effects As Calcium Ions On Resting Membrane Potential?, Anthony Hana, Youngwoo Kim, Joy Bidros, Katie Neglia, Robin L. Cooper
Do Magnesium Ions Have Similar Effects As Calcium Ions On Resting Membrane Potential?, Anthony Hana, Youngwoo Kim, Joy Bidros, Katie Neglia, Robin L. Cooper
Biology Faculty Publications
Maintaining a membrane electrical potential of biological cells is a dynamic process, as some cells have a continually changing potential, like pacemaker cells, while other cells may function with large or small changes in the membrane potential. Additionally, some cells may change their electrical potential when stimulated or inhibited by electrical signals, chemical compounds, or both—either simultaneously or episodically. The persistent leak of K+ through two-pore-domain potassium channels (K2P) and of Na+ through Na+ leak channels (NALCNs) and the action of pumps and exchangers are primarily responsible for maintaining a resting potential. Ca2+ ions are known …
Expressing Experiences Of Being Gender Non-Conforming In The “Ladies” Restroom Through Autoethnography-Based Research Poetics, Ellen D.B. Riggle
Expressing Experiences Of Being Gender Non-Conforming In The “Ladies” Restroom Through Autoethnography-Based Research Poetics, Ellen D.B. Riggle
Gender and Women's Studies Faculty Publications
Three research poems are created as an autoethnographic response to feedback on a research article on the author’s experiences as a gender non-conforming person in women’s public restrooms. The feedback loop includes the sharing of lived experiences by others and theoretical (why?) discussions in the context of the gendered policing and politicalization of women’s restrooms. The first found poem includes words, phrases, and descriptions of images used to label spaces designated as women’s restrooms. The second prose poem recounts the author's experiences through a reframing of risk to women’s health, understanding the cultural context of male entitlement and White supremacy, …
“We Do Things A Little Different Exactly As You'd Expect Here...": Egocentric Network Structures As Predictors Of Organizational Culture Type, Ray Celeste S. Tanner
“We Do Things A Little Different Exactly As You'd Expect Here...": Egocentric Network Structures As Predictors Of Organizational Culture Type, Ray Celeste S. Tanner
Theses and Dissertations--Communication
This dissertation examines organizational culture as an outcome of communication structures by integrating the Competing Values Framework (CVF) with egocentric network analysis. Although CVF is one of the most widely used frameworks for diagnosing organizational culture and predicting organizational effectiveness, prior research has overwhelmingly treated culture as an independent variable. Responding to calls for greater attention to the antecedents of culture, this study reconceptualizes organizational culture as a dependent variable and investigates how individuals’ perceived communication networks predict perceptions of CVF culture types. Using egocentric network data collected from employees across a diverse range of organizations and industries, this study …
Can Love Bloom On A Battlefield: An Analysis Of Queer Militaristic Fanfiction, Brandon Bost
Can Love Bloom On A Battlefield: An Analysis Of Queer Militaristic Fanfiction, Brandon Bost
Theses and Dissertations--Communication
It is noted that readers and fans hold unique and valid interpretations of texts, interpretations that become expressed in fan works like fan art, memes, or the subject of this study, fanfiction. This study performs textual analysis on queer fanfiction in Metal Gear Solid and Code Geass fandoms. It examines the unique relationship militarism holds with intimacy, and how intimacy intersects with violence and control in unique ways in these fan texts. Within these fanfics, militarism can serve as a barrier to intimacy, forcing relationships to adapt to militaristic structures within these fan interpretations.
Exploring The Relationship Between Self-Esteem And Communication Among Equestrians In Facebook Groups, Jenna Young
Exploring The Relationship Between Self-Esteem And Communication Among Equestrians In Facebook Groups, Jenna Young
Theses and Dissertations--Communication
People’s interpersonal relationships and social groups are connected to their self-esteem. Equestrians, a social group unified around riding or working with horses, form identities based on their involvement in the equine industry, whether that be recreationally or professionally. Equestrians’ subjective views of self-esteem may be related to their overall well-being. Theories related to self-esteem and identity indicate that communication within social relationships, like within the equine industry, may impact an individuals’ sense of self-worth. Facebook groups have increased in popularity in the equine industry due to the ease of communication between equestrians. Therefore, this study investigated the relationship between self-esteem …