Digital Commons Network^™

[Review Of] Sfe: The Encyclopedia Of Science Fiction, Robert A. Aken

Library Faculty and Staff Publications

No abstract provided.

Enlivening Election Law, Joshua A. Douglas

Law Faculty Scholarly Articles

Election law cases are often lengthy and include complex discussion of constitutional doctrines. Moreover, there is rarely a clear-cut answer to a tricky election law question. The field is full of balancing tests, competing interests to weigh, and ever-shifting standards. A challenge for Election Law teachers, then, is to ensure that the long judicial opinions and difficult constitutional doctrines undergirding the field of election law do not bury the vibrancy of the topic. One way to keep an Election Law course student-friendly is to make frequent use of electronic media. Election law is well-suited to the adoption of images, videos, …

Sustainable Agriculture Education And Civic Engagement: The Significance Of Community-University Partnerships In The New Agricultural Paradigm, Kim L. Niewolny, Julie M. Grossman, Carmen J. Byker, Jennifer L. Helms, Susan F. Clark, Julie A. Cotton, Krista L. Jacobsen

Horticulture Faculty Publications

Universities and colleges across the United States are making innovative strides in higher education programming to catalyze a more sustainable era of agriculture. This is clearly exemplified through the formation of community-university partnerships as critical illustrations of civic engagement (CE) for sustainable agriculture (SA) education. This paper explores the praxis of CE for SA education by focusing on the ways in which five land-grant universities (LGUs) with undergraduate programs in SA have developed and put into practice community-university partnerships. Drawing upon these programs and supportive literature, this article specifically attempts to describe the role and significance of CE for SA …

Remembering The Thirteen Roses: Blurring Fact And Fiction, Kajsa Larson

Nomenclatura: aproximaciones a los estudios hispánicos

No abstract provided.

La Habana Y Medellín: Dos Mundos Poshumanistas Y Posapocalípticos A Través De La Neblina Del Ayer Y Rosario Tijeras, Osvaldo Di Paolo

Nomenclatura: aproximaciones a los estudios hispánicos

No abstract provided.

Violence And Apocalypse In Ricardo Chávez Castañeda's El Día Del Hurón, Kristina Puotkalyte-Gurgel

Nomenclatura: aproximaciones a los estudios hispánicos

No abstract provided.

Movilidades Posapocalípticas: Un Nuevo Acercamiento A La Película De La Migración Irregular, Arturo Vargas

Nomenclatura: aproximaciones a los estudios hispánicos

No abstract provided.

Modified Rubisco Large Subunit N-Methyltransferase Useful For Targeting Molecules To The Active-Site Vicinity Of Ribulose-1,5-Bisphosphate, Robert L. Houtz

Horticulture Faculty Patents

The present invention generally relates to a modified Rubisco large subunit ^εN-Methyltransferase (Rubisco LSMT, or RLSMT). The present invention also relates to a modified RLSMT-carbonic anhydrase (RLSMT-CA). This modified RLSMT-CA improves the efficiency of the reduction of CO₂ during photosynthesis, which may increase plant growth rates. The present invention also relates to nucleic acids encoding the modified RLSMT-CA or modified RLSMT. Also, the present invention relates to cells including the modified RLSMT-CA or modified RLSMT, plants containing the modified RLSMT-CA or modified RLSMT, and methods using compositions of the present invention. In addition, the present invention relates to …

Poster Session, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Western Kentucky Deep Saline Reservoir CO₂ Storage Test: Shallow Groundwater Monitoring Results, E. Glynn Beck and others, Kentucky Geological Survey
• Baseline Soil Properties of a Central Kentucky Riparian Buffer, Amanda Gumbert and others, Dept of Plant and Soil Science, UK
• The Kentucky Water Well Driller’s Certification Program, Scotty E. Robertson and David A. Jackson, Kentucky Division of Water, Frankfort, KY
• Influences of Cladophora Bloom on the Diets of Amblema plicata and Elliptio dilatata in the Upper Green River, Kentucky, Jennifer M. Yates and others, Dept of Biology, Western Kentucky University
• Using Electrical Resistivity to Locate …

Session 1c, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• The Effects of Prescribed Fire on Amphibian and Reptile Diversity in an Oak-Grassland Restoration Area, Robert Knopp and Howard Whiteman, Dept Biological Sciences and Watershed Studies, Murray State University
• Results of a Data Evaluation to Establish Priority Remediation Areas for Dry Weather Fecal Contamination in a Karst Influenced Watershed, Steve Evans and others, Third Rock Consultants, Lexington, KY
• Development of In-House Methods for High-Throughput DNA Extraction, Kimberly L. Cook and LorraBelle Hill, USDA-ARS, Bowling Green, KY
• Validation of the Sanitary Category Value Model (SCV) for the Identification of Leaking Sewer Lines: A Study of the West Hickman …

Session 1b, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• University – Habitat for Humanity Green Infrastructure Demonstration Project, Nancy Givens and Terry Wilson, WKU Center for Environmental Education and Sustainability, Bowling Green, KY
• Effectiveness of Pollutant Removal in the McConnell Springs Stormwater Quality Wetland Pond and the Gainesway Pond Retrofit Project, Year Two, David J. Price and Susan L. Plueger, Lexington-Fayette Urban County Government
• Coca-Cola Stormwater Replenish Project, Eric Dawalt and Russ Turpin, Ridegewater, LLC and EcoGro, Lexington, KY
• ITEST and LFUCG Stormwater Professional Development, Brian Radcliffe and Carol D. Hanley, Tracy Farmer Institute for Sustainability and the Environment, UK

Proceedings Of 2012 Kentucky Water Resources Annual Symposium, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

This symposium was planned and conducted as a part of the state water resources research institute annual program that is supported by Grant/Cooperative Agreement Number G11AP20081 from the United States Geological Survey. The contents of this proceedings document and the views and conclusions presented at the symposium are solely the responsibility of the individual authors and presenters and do not necessarily represent the official views of the USGS or of the symposium organizers and sponsors. This publication is produced with the understanding that the United States Government is authorized to reproduce and distribute reprints for government purposes.

Development And Functional Analysis Of Novel Genetic Promoters Using Dna Shuffling, Hybridization And A Combination Thereof, Rajiv Ranjan, Sunita Patro, Bhubaneswar Pradhan, Alok Kumar, Indu B. Maiti, Nrisingha Dey

Kentucky Tobacco Research and Development Center Faculty Publications

BACKGROUND: Development of novel synthetic promoters with enhanced regulatory activity is of great value for a diverse range of plant biotechnology applications.

METHODOLOGY: Using the Figwort mosaic virus full-length transcript promoter (F) and the sub-genomic transcript promoter (FS) sequences, we generated two single shuffled promoter libraries (LssF and LssFS), two multiple shuffled promoter libraries (LmsFS-F and LmsF-FS), two hybrid promoters (FuasFScp and FSuasFcp) and two hybrid-shuffled promoter libraries (LhsFuasFScp and LhsFSuasFcp). Transient expression activities of approximately 50 shuffled promoter clones from each of these libraries were assayed in tobacco (Nicotiana tabacum cv. Xanthi) protoplasts. It was observed that most …

Inverse Relationship Between Psa And Il-8 In Prostate Cancer: An Insight Into A Nf-Κb-Mediated Mechanism, Yong Xu, Daret K. St. Clair, Fang Fang, William H. St. Clair

Toxicology and Cancer Biology Faculty Publications

Background: Prostate specific antigen (PSA) is traditionally used as an indicator for the presence of prostate cancer (PCa) and radiotherapy is generally used to treat inoperable and locally advanced PCa. However, how cellular PSA level is associated with sensitivity of PCa to radiotherapy is unknown. The previous finding that the RelB-based NF-κB alternative pathway differentially regulates PSA and interleukin-8 (IL-8) in aggressive PCa has directed our attention to the role of RelB in the response of PCa to radiotherapy.

Methodology/Principal Findings: RelB and its targets PSA and IL-8 in PCa cells were manipulated by ectopic expression in PCa …

Smoking On The Margins? Assessing The Effects Of A Smoke-Free Law In Parks And On Beaches, Ann Pederson, Chizimuzo T.C. Okoli, Wendy Rice, Steve Chasey, Arezu Moshrefzadeh, Joan L. Bottorff, Natalie Hemsing, Lorraine Greaves, Nancy Poole

Nursing Presentations

This study uses a health equity lens to examine the development, adoption and implementation of an outdoor smoke-free bylaw in Vancouver, BC, Canada. The study aims to:

• Understand the health and health equity effects of a new outdoor smoke-free policy in parks and on beaches;

• Assess the differential impacts of the policy for diverse groups of women and men, in particular those with a high prevalence and susceptibility to smoking and those who are exposed to secondhand smoke (SHS);

• Develop recommendations to enhance the effectiveness of future smoke-free policies to reduce any unintended contributions to health inequities arising from their …

You Say You Want An E-Revolution?: Helping Our Patrons Benefit From Developments In Personal Technology, Beau Steenken

Law Faculty Popular Media

In this article, the author provides advice on how libraries and patrons can adapt to changes in technology and the prevalence of personal tech devices.

Equity, Evidence & Ethics: Assessing The Implications Of Outdoor Smoke-Free Policies For Vulnerable Populations, Natasha Jategaonkar, Ann Pederson, Chizimuzo T.C. Okoli, Wendy Rice, Phoebe M. Long, Joan L. Bottorff, Natalie Hemsing, Lorraine Greaves

Nursing Presentations

Smoke-free policies in outdoor settings are becoming increasingly common. Economic and social conditions tend to influence tobacco use patterns as well as exposure to secondhand smoke. Thus, active and passive smoking are both health equity and social justice concerns.

Smoking on the Margins is a multi-component,mixed-methods project that applies an ethical framework to outdoor smoke-free policies in order to identify both concerns and opportunities to promote health and health equity.

Justification for smoke-free policies

Smoke-free spaces are primarily justified on the basis of three goals:

1) Reducing exposure to secondhand smoke;

2) Encouraging people to quit smoking; and

3) Preventing …

Developing And Implementing Strategies To Address “Freddie Freeroader”, David Q. Hunsucker, Mark S. Spellman, Mark Bell

Kentucky Transportation Center Research Report

Although the majority Kentucky’s citizens pay their fair share of motor vehicle registration taxes, there are indications that a number of citizens evade motor vehicle property and usage tax through a variety of means. Some individuals license their cars in states that have no, or very low, property taxes on motor vehicles; others abuse the use of temporary tags, or simply fail to renew the registration on their vehicles. As a result, Kentucky is losing income that would be used to repair the state’s roadways and fund local services such as schools, libraries, health departments, and police and fire services. …

Methodology For Ablation Investigations In The Vki Plasmatron Facility: Preliminary Results With A Carbon Fiber Preform, Bernd Helber, Olivier Chazot, Annick Hubin, Thierry Magin

Ablation Workshop

Following the current developments of a new class of low-density, carbon/resin composite ablators, new efforts were initiated at the VKI on ablation research to understand the complex material response under reentry conditions and to develop and validate new material response models. Promising experimental results were obtained by testing the low-density monolytic composite ablator (MonA) in the 1.2MW inductively heated VKI Plasmatron facility. The application of a high speed camera with short exposure times (2μs) enabled in-situ analysis of both (3D) surface recession and spallation and further made it possible to demonstrate the outgassing effects of pyrolizing ablators. A change in …

Thermo-Chemical And Mechanical Coupled Analysis Of Swelling, Charring And Ablative Materials For Re-Entry Applications, Gregory Pinaud

Ablation Workshop

One of the major challenges in the design of atmospheric reentry vehicles is the optimization of the thermal protection system (TPS). During a reentry, the vehicle encounter severs heating and mechanical stress. A robust sizing is therefore essential to insure vehicle integrity and the mission success. In order to maximize the payload mass of the vehicle, lightweight charring ablators are commonly chosen as TPS materials for this one shot mission.

To predict the behaviour of the TPS ablative materials under pyrolysis for reentry applications, Astrium ST initiated the development of a specific module of the finite element software SAMCEF: AMARYLLIS. …

Radiative Transfer Equation Solver Module For Coupled Simulation Of Hypersonic Flows, Ranjan S. Mehta, Paul J. Dionne, Samuel F. Owens

Ablation Workshop

Accurate numerical modeling of the aerothermal environment around an ablation-cooled hypersonic re-entry vehicle requires high-fidelity models for processes such as non-equilibrium surface themochemistry, non-equilibrium pyrolysis chemistry, multi-scale radiation, spallation and charring. It is expected that, these models when utilized in a coupled manner will be able to accurately capture the possible nonlinear interactions between various phenomena in a computationally efficient manner. Development of a coupled radiative solver is currently being carried out as part of a joint effort between CFDRC, University of Michigan and University of Kentucky to develop a fully coupled method of simulating atmospheric entry flows and response …

Modeling Of Heat Transfer Attenuation By Ablative Gases During The Stardust Re-Entry, Alexandre Martin, Iain D. Boyd

Ablation Workshop

The great majority of modern space vehicles designed for planetary exploration use ablative materials to protect the payload against the high heating environment experienced during re-entry. In order to properly model and predict the aerothermal environment of the vehicle, it is imperative to account for the gases produced by ablation processes. In the case of charring ablators, where an inner resin is pyrolyzed at a relatively low temperature, the composition of the gas expelled into the boundary layer is complex and may lead to thermal chemical reactions that cannot be captured with simple flow chemistry models. In order to obtain …

Ablation Test Case Series #2. Mopar: Results For The Inter-Code Calibration, Jonathan E. Wiebenga, Iain D. Boyd, Alexandre Martin

Ablation Workshop

No abstract provided.

Numerical Investigation Of Three-Dimensional Effects Within A Charring Ablator, Alexandre Martin, Ovais U. Khan, Huai-Bao Zhang

Ablation Workshop

Re-entry of a spacecraft occurs at hypersonic regime where flow field is extremely complex. High temperature gradients occurring in the shock-layer region ionizes and dissociates the air. Even if a large portion of heat generated during this process is convected away in the surrounding air, a fraction of it is still transferred to the vehicle. Therefore, it is important to protect the vehicle with a suitable kind of shielding. Of many techniques available today, the use of ablator material is increasing in popularity. The basic idea behind an ablating heat shield is that the energy incident on the spacecraft is …

Advanced Thermal Protection Systems (Tps) And Transition Analysis: Unique Experimental Capabilities And Current Research Efforts At The University Of Texas At Arlington, Matthew Crisanti, Cody Ground, Stefano Gulli, Jared Poempipatana, Luca Maddalena

Ablation Workshop

A unique experimental capability in the academic panorama is the 1.6 MW-classic arc-jet facility located at the Aerodynamics Research Center of the University of Texas at Arlington. The arc-heated wind tunnel has recently been refurbished and repurposed (extended testing time of the order of minutes and testing gas-composition control) for the study and characterization of the aerothermal response of TPS candidate materials for sustained hypersonic flight.

Active Site Mutations Change The Cleavage Specificity Of Neprilysin., Travis Sexton, Lisa J. Hitchcook, David W. Rodgers, Luke H. Bradley, Louis B. Hersh

Molecular and Cellular Biochemistry Faculty Publications

Neprilysin (NEP), a member of the M13 subgroup of the zinc-dependent endopeptidase family is a membrane bound peptidase capable of cleaving a variety of physiological peptides. We have generated a series of neprilysin variants containing mutations at either one of two active site residues, Phe⁵⁶³ and Ser⁵⁴⁶. Among the mutants studied in detail we observed changes in their activity towards leucine⁵-enkephalin, insulin B chain, and amyloid β_1-40. For example, NEP^F563I displayed an increase in preference towards cleaving leucine⁵-enkephalin relative to insulin B chain, while mutant NEP^S546E was less discriminating …

Bmi-1 Absence Causes Premature Brain Degeneration, Guangliang Cao, Minxia Gu, Min Zhu, Junying Gao, Ying Yin, Charles Marshall, Ming Xiao, Jiong Ding, Dengshun Miao

Physical Therapy Faculty Publications

Bmi-1, a polycomb transcriptional repressor, is implicated in cell cycle regulation and cell senescence. Its absence results in generalized astrogliosis and epilepsy during the postnatal development, but the underlying mechanisms are poorly understood. Here, we demonstrate the occurrence of oxidative stress in the brain of four-week-old Bmi-1 null mice. The mice showed various hallmarks of neurodegeneration including synaptic loss, axonal demyelination, reactive gliosis and brain mitochondrial damage. Moreover, astroglial glutamate transporters and glutamine synthetase decreased in the Bmi-1 null hippocampus, which might contribute to the sporadic epileptic-like seizures in these mice. These results indicate that Bmi-1 is required for maintaining …

Ipla2Β Overexpression In Smooth Muscle Exacerbates Angiotensin Ii-Induced Hypertension And Vascular Remodeling, Lindsay E Calderon, Shu Liu, Wen Su, Zhongwen Xie, Zhenheng Guo, Wanda Eberhard, Ming C. Gong

Physiology Faculty Publications

OBJECTIVES: Calcium independent group VIA phospholipase A₂ (iPLA₂β) is up-regulated in vascular smooth muscle cells in some diseases, but whether the up-regulated iPLA₂β affects vascular morphology and blood pressure is unknown. The current study addresses this question by evaluating the basal- and angiotensin II infusion-induced vascular remodeling and hypertension in smooth muscle specific iPLA₂β transgenic (iPLA₂β-Tg) mice.

METHOD AND RESULTS: Blood pressure was monitored by radiotelemetry and vascular remodeling was assessed by morphologic analysis. We found that the angiotensin II-induced increase in diastolic pressure was significantly higher in iPLA₂β-Tg …

A Co-Opted Dead-Box Rna Helicase Enhances Tombusvirus Plus-Strand Synthesis, Nikolay Kovalev, Judit Pogany, Peter D. Nagy

Plant Pathology Faculty Publications

Replication of plus-strand RNA viruses depends on recruited host factors that aid several critical steps during replication. In this paper, we show that an essential translation factor, Ded1p DEAD-box RNA helicase of yeast, directly affects replication of Tomato bushy stunt virus (TBSV). To separate the role of Ded1p in viral protein translation from its putative replication function, we utilized a cell-free TBSV replication assay and recombinant Ded1p. The in vitro data show that Ded1p plays a role in enhancing plus-strand synthesis by the viral replicase. We also find that Ded1p is a component of the tombusvirus replicase complex and Ded1p …

The Tpr Domain In The Host Cyp40-Like Cyclophilin Binds To The Viral Replication Protein And Inhibits The Assembly Of The Tombusviral Replicase, Jing-Yi Lin, Venugopal Mendu, Judit Pogany, Jun Qin, Peter D. Nagy

Plant Pathology Faculty Publications

Replication of plus-stranded RNA viruses is greatly affected by numerous host-coded proteins acting either as susceptibility or resistance factors. Previous genome-wide screens and global proteomics approaches with Tomato bushy stunt tombusvirus (TBSV) in a yeast model host revealed the involvement of cyclophilins, which are a large family of host prolyl isomerases, in TBSV replication. In this paper, we identified those members of the large cyclophilin family that interacted with the viral replication proteins and inhibited TBSV replication. Further characterization of the most effective cyclophilin, the Cyp40-like Cpr7p, revealed that it strongly inhibits many steps during TBSV replication in a cell-free …