Digital Commons Network^™

Torque-Speed Characteristic Estimation Based On Gaussian Processes And Adaptive Sampling Strategy For Permanent Magnet Synchronous Machines, Marcelo D. Silva, Pedram Asef, Oluwaseun A. Badewa, Rosemary E. Alden, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Internal Permanent Magnet Synchronous Machines (IPMs) are widely used and typically optimized to meet specific performance requirements. Parameters such as base speed, maximum torque, and maximum speed commonly define the torque- speed characteristic of a given design. This study introduces a novel machine learning approach for statistically estimating the torque-speed characteristics of IPMs using Gaussian Process Regression (GPR), which models predictions as random variables. By leveraging uncertainty quantification, the study explores sampling strategies that enable the construction of a high-precision meta-model with minimal error and uncertainty. The proposed adaptive sampling strategy, combined with GPR, accurately estimates torque-speed characteristics and associated …

Degradation Minimization Of Utility-Scale Li-Ion Bess Through Operational Optimization Employing An Equivalent Circuit Model, Kwabena A. Kyeremeh, Grant M. Fischer, Donovin D. Lewis, Aron Patrick, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

The increasing deployment of utility-scale battery energy storage systems (BESS) necessitates effective strategies for supporting grid services while minimizing degradation that may compromise system longevity. High charge/discharge rates (C-rate) and imbalanced operation of multi-unit BESS configurations may accelerate degradation. This paper proposes a degradation-aware operational optimization based on Model Predictive Control (MPC) for coordinating multiple BESS units under physical and operational constraints. The multi-objective optimization model imposes penalties on C-rate magnitude, operational state-of-charge (SoC) disparity, and battery internal resistance modeled using an equivalent circuit model. A case study conducted for a fleet of BESS units over a one-week load profile …

Air Traffic–Collegiate Training Initiative Program Feasibility In Kentucky, Gayle Marks, Bryan Gibson

Kentucky Transportation Center Research Report

Each day, Federal Aviation Administration (FAA) air traffic control specialists (ATCSs) handle over 44,000 flights and oversee 29 million square miles of the United States National Airspace System. However, staffing shortages have grown more acute over the past 10 years, which has led to delayed and cancelled flights, a higher number of close misses over a short period of time, and frustrating air travel experiences. While the FAA has redoubled its efforts to recruit more ATCSs, it has limited training capacity. To expand training options available to prospective ATCSs, the FAA is working with postsecondary educational institutions to expand its …

Data Center Developments For Flexible Generation Dispatch, Advanced Infrastructure, And Ultra-Fast Digital Twins, Grant M. Fischer, Rosemary E. Alden, Donovin D. Lewis, Aron Patrick, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

The rapid advancement and widespread integration of artificial intelligence (AI) is driving demand for unprecedented deployment of power-intensive computational infrastructure, including multi-megawatt data centers with the potential for facilities with gigawatt-scale capacity in the near future. In this paper, load growth projections for the US are reviewed, and an example energy dispatch solution considering a mixed energy portfolio with flexible, renewable, distributed, and load-based generation is employed. The brief technology review included in the paper covers aspects of electric power, cooling, and computational infrastructures. The concept of a data center digital twin for transient load, grid interaction, and hybrid energy …

Hypogammaglobulinemia And Infection Rates In Patients With Multiple Sclerosis Treated With Ocrelizumab For Up To Six Years, B. Khatri, P. Van Zealand, S. Tarima, S. Schutten, A. Baker, T. Perea

Biostatistics Faculty Publications

Objectives and aims: Ocrelizumab (OCR) is disease-modifying therapy that depletes B cells for the treatment of patients with relapsing and progressive multiple sclerosis (MS). The aim of this study was to evaluate occurrence of hypogammaglobulinemia and infection rates in patients with MS treated with OCR for up to 5.9 years in a real-world, single-center study. Methods: We assessed immunoglobulins IgG, IgM, IgA; CD19, CD4, CD8 cell counts, anti-JCV antibodies, at baseline and every six months prior to each OCR infusion. Mixed effects regression models controlling for random patient intercept were used to analyze immunological trends. Infections requiring oral or intravenous …

Iodinated Disinfection Byproduct Formation From Iohexol In Sunlit And Chlorinated Urban Wastewaters, Reagan Patton Witt, Marcelo I. Guzman

Chemistry Faculty Publications

No abstract provided.

Understanding Rural Health Through Rae Garringer's Country Queers: A Love Letter, Bradley A. Firchow

Journal of Appalachian Health

Rae Garringer’s Country Queers: A Love Letter examines the experiences of queer individuals in rural America, emphasizing the relationship between place and identity. Through oral histories, the book presents perspectives on community, resilience, and healthcare access. While not centered on medical care, it highlights challenges in obtaining affirming services in rural areas. Garringer’s experience as a standardized patient provides additional context on healthcare gaps. For public health professionals, Country Queers offers insight into the structural and social factors affecting rural LGBTQ2+ populations, contributing to a broader understanding of community health and identity in Appalachia and similar regions.

The Status Of Children’S Dental Health In Rural Appalachian West Virginia, R. Constance Wiener, Gina Graziani

Journal of Appalachian Health

Introduction: Non-metro/rural Appalachian West Virginia (WV) residents have been stigmatized for poor oral health (OH), despite many advances.

Purpose: The aims of this study were to examine current OH in children in WV, as compared to children in the greater United States (U.S.), and secondarily in subgroup non-metro/rural comparisons.

Methods: This observational study involved the U.S. National Survey of Children’s Health 2022–2023 data from parents/guardians who were asked about their child’s previous 12-month OH. Rao-Scott Chi-square and logistic regression analyses were used.

Results: Nationally, the mean age was 9.7 years; for WV children, it was 9.9 years. Nationally, 12.4% of …

Identifying Barriers And Place-Based Solutions To Physical Activity For Older Adults In East Tennessee, Lydia Hoskins, Jodi Southerland

Journal of Appalachian Health

Introduction: Older adults in East Tennessee (TN), the fastest growing demographic, face significant health challenges, with 44% reporting four or more chronic conditions. The state ranks 45th in physical inactivity among older adults, exacerbating chronic disease risks, fall-related injuries, and mental health issues. Urban-rural disparities in East TN further complicate efforts to promote active living, particularly for rural residents.

Purpose: This qualitative study explored socioecological barriers and solutions to increase physical activity (PA).

Methods: In April 2024, two focus group were conducted in East TN, with a total of 11 participants composed of six community partners and five older adults. …

Finding Community: A Thematic Analysis Of Resilience During The Pandemic, Myles Kwitny, Quinn Richards, Grace Digirolamo, Shannon Freedman, Sophie Wenzel

Journal of Appalachian Health

Introduction: The Covid-19 pandemic impacted those within rural Appalachian communities, particularly people with marginalized identities.

Purpose: Through interviewing 44 participants from New River Valley, an Appalachian community in Virginia, this study sought to understand how resilience impacted individuals' experiences during the pandemic.

Methods: Participants belonged to one of the following groups: African American, Hispanic, older adults, or people who use drugs. Participants were required to reside in the New River Valley and be older than 18. Each participant was interviewed either in person, by phone, or over video call. Interviews were recorded, transcribed, then thematically analyzed for themes of resilience. …

Addressing The Root Causes Of Population Health In Central Appalachian Virginia, David L. Driscoll, Kol Gold

Journal of Appalachian Health

Introduction: The Southwest Virginia Health Authority (SWVHA) recently commissioned a community health needs assessment (CHNA) to reduce the high rate of preventable health problems in Virginia’s (VA) Appalachian Region. The CHNA took place over a two-year period from 2023 – 2025.

Purpose: This iterative, mixed-method CHNA informed the development of a new iteration of the regional Blueprint for Health Improvement and Health-Enabled Prosperity identifying and prioritizing health issues and develop strategic planning to address them in VA’s three westernmost regional health districts.

Methods: The CHNA followed a sequential mixed methods design to assess the regional health status, the contextual factors …

Multidimensional Biocircuitry Of Exercise Adaptation, Jeremy S. Mcadam, Zachary A. Graham, S. Craig Tuggle, Kaleen M. Lavin, Marcas M. Bamman, Jeremy S. Mcadam, Zachary A. Graham, Brandon Peoples, Regina S. Seay, Kaleen M. Lavin, Amber B. Gargus, Sufen Yang, Samia M. O’Bryan, Devin J. Drummer, Christian J. Kelley, Margaret B. Bell, Inmaculada Aban, Gary R. Cutter, Marcas M. Bamman, Michael P. Craig, Jin Zhang, Akshay Hira, Timothy J. Broderick, Madhavi P. Kadakia, Zachary A. Graham, Kalyani Peri, Margaret B. Bell, Inmaculada Aban

Physiology Faculty Publications

In a randomized, dose-response trial, we used molecular and phenomic profiling to compare responses with traditional moder ate-intensity endurance and resistance training (TRAD) versus high-intensity tactical training (HITT) that encompassed explosive whole-body interval training and high-intensity resistance training. Ninety-four participants (18–27 yr) completed 12 wk of TRAD or HITT followed by 4 wk of detraining. Although similar performance and body composition improvements were observed in response to HITT and TRAD, some dose-dependent differences were observed for: 1) ex vivo muscle tissue changes in myofiber size, capillarization, satellite cell frequency, and mitochondrial function and 2) differential gene expression (DGE) of muscle …

“Literally Made Me Cry”: The Impact Of Course Material Costs On University Of Kentucky Students, Stephen Krueger

Library Reports and White Papers

The Student Course Materials Cost Survey was administered September 16 – October 6, 2024. It was open to current students at the University of Kentucky (UK). The goals were to help UK Libraries better understand how the cost of course materials affects students at UK and to provide a snapshot of student spending across the university. The questions were based on similar research done at other institutions in Virginia (Virginia Course Materials Survey, 2021) and Florida (2022 Student Textbook and Instructional Materials Survey, 2022). Other work based on those surveys includes the 2023 Illinois Course Materials Survey (CARLI, 2023) and …

Tobacco Marketing Exposure And Lifetime And Current Nicotine Pouch Use Among Us Youth, 2022, Saber Feizy, Delvon T. Mattingly, Melinda Ickes, Mary Kay Rayens, W. Jay Christian, Melissa Abadi, Seth Himelhoch, Shyanika W. Rose

Epidemiology and Environmental Health Faculty Publications

Objective: The rising popularity of nicotine pouches among youth necessitates an understanding how marketing exposure influences their use, to inform regulation. This study examines the associations of tobacco marketing exposures with nicotine pouch use among adolescent students in the United States. Methods: We analyzed data from 26,860 middle and high-school students in the United States who participated in the 2022 National Youth Tobacco Survey. The survey was administered during January–May 2022. Weighted logistic regressions with and without covariates (i.e., sociodemographic characteristics, other tobacco product use, and social media use) were used to evaluate the relationships between exposure to a variety …

Bike/Ped Data Collection And Model Calibration, Eirini Stavropoulou, Dionysios Tzamakos, Nikiforos Stamatiadis, Reginald Souleyrette, Teng Wang

Kentucky Transportation Center Research Report

Motivated by an uptick in pedestrian and bicycle traffic, as well as the inclusion of pedestrian and bicyclist weights in the Strategic Highway Investment Formula For Tomorrow, the Kentucky Transportation Cabinet (KYTC) has made significant investments in transportation facilities for nonmotorized users. Despite an intensified focus on the needs of nonmotorized users, KYTC has not yet established a formal program to track the number of people walking, biking, skateboarding, and using micromobility devices statewide. Based on a review of methods and technologies for counting nonmotorized users; analysis of counting programs established by local, state, and regional transportation agencies; and a …

Transferrin Receptor 1 Deficiency In Smooth Muscle Cells Attenuates Vascular Remodeling In Hypertensive Mice, Yoshiro Naito, Hisashi Sawada, Tetsuo Horimatsu, Masaki Ohmuraya, Masanori Asakura, Masaharu Ishihara

Physiology Faculty Publications

Transferrin receptor 1 (TfR1), a crucial cellular iron receptor, has a variety of biological functions. We have previously reported that TfR1 abundance increases in the aortic media of hypertensive rat models. However, its role in vascular diseases remains unknown. In the present study, we generated smooth muscle cell (SMC)-specific TfR1 deficient mice and examined the impact of its deletion in mouse models of hypertension induced by angiotensin II or deoxycorticosterone acetate/salt administration. SMC-specific TfR1 deletion attenuated medial thickening and elastin fragmentation in both mouse models of hypertension. These results indicate that TfR1 in SMCs exerts a role in vascular remodeling …

Improved Efficiency Of Plant Regeneration From Smooth Bromegrass (Bromus Inermis) Suspension Culture, T H. Chen, J Marowitch

IGC Proceedings (1977-2023)

Smooth bromegrass, Bromus inermis Leyss, is the most important forage grass in Canada. Breeding for improvements such as higher yield and faster regrowth has made little progress, mainly due to the polyploidy and cross-pollination which are characteristic of this grass. The application of tissue culture methods to bromegrass improvement holds promise only if an efficient procedure for plant regeneration is found. Various basal culture media and auxins were tested for their effects on callus induction, growth of suspension cultures and plant regeneration. None of the tested auxins gave better in vitro growth than 2,4-D. Eriksson's medium with 2,4-D as the …

Receptor-Mediated Spion Labeling Of Cd4+ T Cells For Longitudinal Mri Tracking Of Distribution Following Systemic Injection In Mouse, Yu Ping, Songyue Han, Brock Howerton, Francesc Marti, Jake Weeks, Roberto Gedaly, Reuben Adatorwovor, Fanny Chapelin

Surgery Faculty Publications

Tracking T cells in vivo using MRI is a major challenge due to the difficulty of labeling these non-phagocytic cells with a sufficient contrast agent to generate a detectable signal change. In this study, we explored CD4-Superparamagnetic iron oxide nanoparticles (SPION), which is commonly used in magnetic cell sorting, as a potential receptor-mediated, specific CD4+ T cell MRI labeling agent. We optimized the labeling protocol for maximal CD4+ cell labeling and viability. Cell health was confirmed with trypan blue assay, and labeling efficacy was confirmed with Prussian blue staining, transmission electron microscopy, and MRI of labeled cell pellets. Key cell …

Who Reconstitutes The Chemotherapy? The Educational And Practice Needs Of Oncology Pharmacists In West Africa: A Call For Multidisciplinary Team Approach In Oncology Care., Runcie C.W. Chidebe, Ramatu M. Alabelewe, Krishna Prasad Sapkota, Darlingtina K. Esiaka, Candidus C. Nwakasi, Gloria C. Okwu, Jacinta Emejulu, Adamu A. Umar, Ndifreke Okwuegbunam, Funsho David, Toyosi Adepoju, Agha A. Agha, Ejike S. Ugwu, Simeon C. Aruah, Richard Mshelia, Rob Duncombe, Noel N. Wannang, Peace C. Babalola, R. Donald Harvey, Cindy O'Bryant, Folakemi T. Odedina

Behavioral Science Faculty Publications

PURPOSE: Oncology pharmacists (OPs) play a crucial role in cancer care, treatment, survivorship, and multidisciplinary teams (MDTs). OPs have specialized training in designing, administering, monitoring, and modifying oncology chemotherapy; managing adverse events; and evaluating clinical trials and investigational drugs. Yet, the state of OP has remained largely unknown in the clinical oncology workforce of the West African region. Therefore, this study aimed to understand who reconstitutes chemotherapy and to explain the OP educational and practice needs, challenges, and solutions in Nigeria.

MATERIALS AND METHODS: Using a concurrent embedded mixed method design, 35 OPs completed a questionnaire, and 12 others responded …

Step By Step, Patrick M. Filanowski, Jeremy A. Steeves, Emily Slade

Biostatistics Faculty Publications

Background/Objectives: Although public health organizations encourage family walking, no studies have examined children’s physical activity and enjoyment during outdoor parent–child walks. This study addresses those gaps by examining children’s moderate-to-vigorous physical activity (MVPA) and enjoyment during outdoor walks with their parents, along with parental barriers and their relationship with parent’s self-efficacy and co-activity minutes. Methods: Fifty parent–child dyads (children aged 6–12 years) completed 10 min, self-paced outdoor walks while wearing waist-worn ActiGraph monitors. Parents reported perceived barriers to walking outdoors with their child and self-efficacy for supporting their child’s daily physical activity. Results: Children reported high enjoyment (mean = 5.1 …

Endothelium- And Fibroblast-Derived C-Type Natriuretic Peptide Prevents The Development And Progression Of Aortic Aneurysm, Aisah A. Aubdool, Amie J. Moyes, Cristina Perez-Ternero, Reshma S. Baliga, Jaspinder Singh Sanghera, M. Taaha Syed, Kareemah Jaigirdar, Anmolpreet K. Panesar, Janice C. Tsui, Yanming Li, Hernan G. Vasquez, Ying H. Shen, Scott A. Lemaire, Juliette Raffort, Ziad Mallat, Hong S. Lu, Alan Daugherty, Adrian J. Hobbs

Physiology Faculty Publications

BACKGROUND: Thoracic (TAA) and abdominal (AAA) aortic aneurysm are life-threatening diseases characterized by dilation, inflammation, and structural weakness; development of pharmacological therapies is desperately needed. CNP (C-type natriuretic peptide) plays a key role in vascular homeostasis, mediating vasodilator, anti-inflammatory, and antiatherogenic actions. Since such processes drive AA, we determined the role of endogenous CNP in offsetting pathogenesis. METHODS: Tissue from patients with AA was analyzed to determine the consequences on CNP signaling. Ascending and suprarenal aortic diameters were assessed at baseline and following Ang II (angiotensin II; 1.44 mg/kg per day) infusion in wild-type, endothelium-restricted (ecCNP^-/-), fibroblast-restricted (fbCNP …

The Rhetoric Of Responsibilization: A Rhetorical Analysis Of Pre-Exposure Prophylaxis Campaigns For Hiv Prevention, Catherine M. Pabalate

Kentucky Undergraduate Journal for the Health Humanities

Responsibilization refers to the process by which patients are made accountable for their health and wellbeing, which is determined by their habits and behaviors. Though responsibilization affords greater agency to patients, it can also result in anxiety and guilt when the patient appears "deviant" or "noncompliant." Because sexual behavior is attributed to the causality of HIV/AIDS, patients’ sexual patterns and choices are included within their medical decision-making. This rhetorical analysis focuses on pharmaceutical campaigns and commercials for pre-exposure prophylaxis (PrEP), which were released between 2012 and 2024 and are targeted towards patients at-risk for HIV/AIDS. Findings suggest that specific rhetorical …

You Are Here: Defining Our Hidden Born-Digital Backlog, Andrew Mcdonnell

Library Presentations

The digital archivist position was created at the University of Kentucky two years ago to help create and refine workflows and process born-digital collections in our manuscripts and university archives collections. While much of the initial work of these last two years was on newly acquired collections and materials, in the decades prior, a variety of born-digital materials on physical media had been gathered in hybrid collections and stored and described in myriad ways. This presentation will demonstrate my processes for discovering and assessing unmigrated born-digital materials on physical media hidden throughout our collection. The process is built on documentation …

Development Of A Health And Wellness Assessment For Kytc Personnel, Gabriel Dadi, Farshid Taherpour, Caitlin Pope

Kentucky Transportation Center Research Report

Highway construction workers operate in high-stress, hazardous settings where they have to perform physically taxing labor in environments where exposure to variable weather conditions, heavy equipment, high volumes of vehicle traffic, and other conditions that induce stress and anxiety are the norm. Up to 70% of workers in this industry have reported experiencing mental health issues, including secondary traumatic stress, post-traumatic stress disorder, depression, anxiety, and substance abuse disorders. Few state departments of transportation, however, offer adequate resources staff can draw on to effectively manage their psychological well-being. To help Kentucky Transportation Cabinet (KYTC) roadway maintenance and construction workers develop …

Aggregator Zone Selection For Ev Smart Controls Based-On Ml Clustering Of Grid Strength, Distance, And Charging Homogeneity, Rosemary E. Alden, Sam H. Lowe Ii, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Smart electric vehicle (EV) charging control methods from a central utility hub often require communication infrastructure over a large service area of electric power distribution systems with a large number of nodes. Industry standards such as Open Charge Point Protocol (OCPP) 2.1 have evolved to include topologies for local controllers to the individual chargers, i.e. EV aggregator zones. A machine learning (ML) application of k-means clustering is proposed to establish zones for coordination of EV charging based on grid strength and EV owner decision-making to charge per day. Very large-scale distribution networks including the IEEE 123 and 8500 benchmark feeders …

Cluster-Based Volt/Var Optimization On A Utility Distribution Feeder With Forecasted Ev Penetration, Steven B. Poore, Grant M. Fischer, Rosemary E. Alden, Evan S. Jones, Aron Patrick, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

With significant increase in EV adoption expected in the near future and the associated impacts on power systems, the effect of volt/var optimization (VVO) as the next step to conservation voltage reduction (CVR), requires reevaluation. Implementation of a cluster-based VVO control strategy employs a novel approach with machine learning (ML) load forecasting to reduce device adjustments through k-means clustering of contiguous time steps with similar active power load in which a single adjustment would be sufficient. The cluster-based VVO method is tested on a complex real world utility distribution feeder with 2,018 nodes, 8.65MW peak load, 9 capacitor banks (CBs), …

Hybrid Fea And Meta-Modeling For De Optimization Of A Pm Stator-Excited Motor With A Reluctance Rotor, Oluwaseun A. Badewa, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

This paper presents an innovative method for designing high-performance electric motors by integrating machine learning (ML) based meta-modeling with a differential evolution (DE) optimization algorithm. The approach utilizes finite element analysis (FEA) data to train the ML meta-model, allowing for efficient optimization of high-power-density machines, such as the reluctance rotor and permanent magnet (PM) stator combined excitation motor, which is characterized by nonlinearities. The meta-modeling process employs an Artificial Neural Network (ANN) with 3 hidden layers and uses the motor’s geometrical variables as inputs. The accuracy of the meta-model in capturing the nonlinear relationships between design parameters, core losses, and …

Three And Two Phase Rotating Field Inductive Couplers For Wireless Power Transfer With One Phase Per Layer Windings, Donovin D. Lewis, Lucas Gastineau, Omer Onar, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Multiphase inductive wireless charging coils have been proposed recently to improve coupler surface power density, reduce component stress and size, and provide near-constant power delivery to charge mobile electric systems. Several aspects for the fundamental characterization of multiphase coils are explored up to six phases including approximate mutual inductance with size and turn variation, induced voltage, and output power estimation. The relative component stress and size of passive components for resonant operation are compared between the multiphase variants. A combination of an experimentally validated 3D electromagnetic finite element analysis (FEA) and power electronic co-simulations are used to validate the estimated …

Cryogenic Thermal System For Coreless Axial Flux Pm Machine With Litz Wire Winding For Electric Aircraft Propulsion, Matin Vatani, Chaianan Sailabada, Philippe Masson, Juan C. Ordonez, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Electric machines for aviation demand ultra-efficient, compact designs with high specific power density, which can be achieved through advancements in both electromagnetic design and thermal management. This paper proposes and investigates an integrated thermal management approach for a coreless stator axial flux permanent magnet (AFPM) machine featuring a double-sided Halbach array PM rotor, two stators, and an aluminum nitride (AlN) cold plate positioned between the stators for direct cooling. The cold plate incorporates internal serpentine channels for liquid hydrogen circulation. The electromagnetic performance and efficiency of the machine at cryogenic temperatures are assessed using temperature-dependent data from the literature, indicating …

Mitigation Of Pm Eddy Current Losses Using Offset Windings In Coreless Afpm Machines, Matin Vatani, Diego A. Lopez Guerrero, John F. Eastham, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Permanent magnet eddy current losses can become substantial in coreless stator axial flux permanent magnet (AFPM) machines operating at high speeds and under high electric loading, potentially leading to elevated temperatures and an increased risk of demagnetization. This paper investigates the origins of these losses through a detailed harmonic analysis of the winding factor and introduces a mitigation strategy. The proposed method utilizes two-layer offset windings, effectively minimizing undesirable armature flux harmonics through harmonic interaction between the offset layers. Two cases are studied: one in which each stator layer is connected to a separate inverter and another in which both …