Digital Commons Network^™

Consistent Gas-Phase Temperatures And Metallicities From Uv And Optical Nebular Emission, Erin Huntzinger, Yuguang Chen, Tucker Jones, Ryan Sanders, Peter Senchyna, Daniel Stark, Fabio Bresolin, Stephane Charlot, Jacopo Chevallard

Physics and Astronomy Faculty Publications

The rest-frame ultraviolet (UV) spectra of star-forming galaxies are increasingly important as they become one of the primary windows to probe the physical properties of cosmic dawn (z > 8) galaxies with the James Webb Space Telescope. However, the systematic discrepancies between UV and optical gas-phase metallicity measurements remain poorly understood in the local universe, partly due to challenges in achieving precise comparisons between UV and optical spectra for the same objects. In this work, we introduce a novel method that leverages the He II λ1640 and He II λ4686 nebular emission lines to achieve accurate aperture and reddening corrections between …

Multi-Jurisdictional Hazard Mitigation Plan For Landslides For The Kentucky River Area Development District, Kentucky, Hudson J. Koch, Matt M. Crawford, Jason M. Dortch

Contract Reports--KGS

Landslides are a widespread and complex geologic hazard that affects people and infrastructure. The Kentucky River Area Development District, Kentucky, sustains relatively high landslide activity that impacts several municipalities in eastern Kentucky. This hazard mitigation planning project outlines landslide hazard and risk assessments for the Kentucky River Area Development District, with information needed for each community in the region to develop mitigation strategies that will support infrastructure and development needs, land-use planning, situational awareness, and response and recovery actions for the communities.

Joint Map Of Warren County, Kentucky, Steven L. Martin, Emily R. Morris

Map and Chart--KGS

This fracture map is a compilation of joint locations and faults mapped in Warren County, Kentucky, and provides orientations of fractures (joints and faults) for hydrological, geotechnical, slope stability, and rockfall mitigation analysis. The joint data include orientations collected from 2023 to 2024, and those collected during the U.S. Geological Survey (USGS) geologic mapping of the Woodburn 7.5 -minute quadrangle (Shawe, 1963c). New joint orientations were measured to fill gaps in the published geologic map data. Joints are fractures with no appreciable movement parallel to the fracture plane and only slight movement normal to the fracture plane, whereas faults exhibit …

Simulation And Optimization Of The Active Magnetic Shield Of The N2edm Experiment, N. J. Ayres, G. Ban, G. Bison, K. Bodek, V. Bondar, T. Bouillaud, G. L. Caratsch, E. Chanel, W. Chen, C. Crawford, V. Czamler, C. B. Doorenbos, S. Emmeneger, S. K. Ermakov, M. Ferry, M. Fertl, A. Fratangelo, D. Galbinski, W. C. Griffith, Z. D. Grujic, K. Kirch, V. Kletzl, J. Krempel, B. Lauss, T. Lefort, A. Lejuez, K. Michielsen, J. Micko, P. Mullan, O. Naviliat-Cuncic, F. M. Piegsa

Physics and Astronomy Faculty Publications

The n2EDM experiment at the Paul Scherrer Institute aims to conduct a high-sensitivity search for the electric dipole moment of the neutron. Magnetic stability and control are achieved through a combination of passive shielding, provided by a magnetically shielded room (MSR), and a surrounding active field compensation system by an Active Magnetic Shield (AMS). The AMS is a feedback-controlled system of eight coils spanned on an irregular grid, designed to provide magnetic stability to the enclosed volume by actively suppressing external magnetic disturbances. It can compensate static and variable magnetic fields up to ± 50 μT (homogeneous components) and ± …

Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, Hunter N.B. Moseley

Markey Cancer Center Faculty Publications

Background: Almost all correlation measures currently available are unable to directly handle missing values. Typically, missing values are either ignored completely by removing them or are imputed and used in the calculation of the correlation coefficient. In either case, the correlation value will be impacted based on the perspective that the missing data represents no useful information. However, missing values occur in real datasets for a variety of reasons. In metabolomics datasets a major reason for missing values is that a specific measurable phenomenon falls below the detection limits of the analytical instrumentation (left-censored values). These missing data are not …

Role Of Succinate Dehydrogenase In Age-Related Th17 Inflammation, Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica-Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath

Markey Cancer Center Faculty Publications

Age-related cellular changes negatively impact CD4⁺ T cell function. Our prior work showed that mitochondrial complex II (succinate dehydrogenase [SDH]) expression was upregulated in T cells from older (O) adults (60–80 years old). T cells from older adults also produced higher amounts of cytokines generally considered proinflammatory, such as Th17 cytokines IL-17A/F and IL-21, and the Th-17-supportive cytokine IL-6, compared to T cells from younger (Y) adults (25–40 years old). The objective of our study is to evaluate whether hyperactivation of SDH is required for the induction of proinflammatory cytokines and the mechanistic link between SDH and Th17 cytokine …

Generative Models And Synthetic Data In Clinical Prediction Models, Anthony A. Mangino, Taha Ahmed, Vincent L. Sorrell

Radiology Faculty Publications

Introduction: Reproducibility, consistency, and transparency are essential to responsible and ethical scientific inquiry, though practices supporting these qualities are often neglected. However, in many cases data are confidential or otherwise unable to be shared publicly. This tutorial describes a method utilizing generative adversarial networks (GANs) to create synthetic data that are sufficiently similar to the original dataset in such cases where the source data cannot be shared or where the source data are too sparse as to internally validate results. Methods: Utilizing an exemplar study that aimed to create a clinical prediction model employing a novel echocardiographic measurement to differentiate …

Happy Belated Iep: How A Notice Of Procedural Safeguards Fails Children With Specific Learning Disabilities, Chrystal Clodomir

Kentucky Law Journal

No abstract provided.

Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss

Progress in Scale Modeling, an International Journal

The phenomenon of Taylor or shear-induced dispersion of a non-passive scalar field in a pulsatile pipe flow is investigated, accounting for the scalar field's influence on fluid density and transport coefficients. By employing multiple scale analysis, an effective one-dimensional, unsteady mixing problem for the scalar field is obtained, which includes the diffusion coefficient for shear-induced dispersion. The resulting governing equations are applicable to a range of scalar transport problems in pulsatile pipe flows.

Methane Emissions From Underground Coal Mines, Marcelo Guzman, Thomas Parris, Stephen Greb, Cortland F. Eble, Sean Bailey

Mechanical Engineering Faculty Publications

Methane emissions from Kentucky underground coal mines were measured using near-infrared spectrometers deployed on a vehicle, an airplane, and a small uncrewed aerial system (sUAS), offering insights into the effectiveness of these methods under real-world conditions. From 2021–2022, surveys covered 14 active, 4 inactive, and 4 abandoned mines across Kentucky’s coal-producing basins. Vehicle-based surveys at 13 active mines detected methane anomalies at 9 sites with anomaly lengths spanning tens to hundreds of meters and peak emissions of 665 ± 229 kg h–1 from two Cardinal mine fans. Airborne GHGSat surveys identified anomalies at 3 sites, including a peak of 1062 …

Scratch-Induced Damage Of Doped Dlc And Mos2 Coatings—Deep Symbolic Analysis, Ming Liu, Zhitong Xu, Noraphat Yuktanan, Tang Gu, Guangan Zhang, Jinyang Jiang, Fuqian Yang, Rui Liang

Chemical and Materials Engineering Faculty Publications

Understanding contact-induced damage is of paramount importance in the analysis of the lifespan and performance of surface coatings. In this work, we investigate the effects of dopants and interlayers on the structural durability of diamond-like carbon coatings (DLCs) and molybdenum disulfide (MoS₂) coatings on stainless steel via microscratch tests. The analysis of X-ray photoelectron spectroscopy (XPS) survey spectra and Raman spectra of the DLCs shows that the ratio of sp²/sp³ (i.e., the intensity ratio of sp² to sp³ obtained via XPS) is proportional to I_D/I_G, where I_D and …

Synthesis And Structures Of Ru(Ii)-P-Cymene Sandwich Complexes With Electron-Withdrawing Cyclopentadienyl Ligands, Uttam R. Pokharel, Sean Parkin, John P. Selegue

Chemistry Faculty Publications

A modular synthetic route has been developed to prepare a new series of cationic ruthenium(II) complexes with electron-withdrawing 1,2-diacylcyclopentadienyl ligands. The 2-acyl-6-hydroxyfulvenes were synthesized from cyclopentadienide and acyl chlorides and converted to Tl(I) cyclopentadienyl salts using Tl₂SO₄/KOH. Transmetalation with [Ru(η⁶-p-cymene)(μ-Cl)Cl]₂ followed by PF₆⁻ metathesis gives the complexes [Ru{η⁵-1,2-C₅H₃(CO–R)₂}(η⁶-p-cymene)][PF₆] (R = t-Bu, p-Tol, p-ClC₆H₄, p-IC₆H₄) in moderate to high yields. The new compounds were characterized by NMR and IR spectroscopy; mass spectrometry …

Stress-Induced Bandgap Modulation In Semiconductor Quantum Wells, Saurabh Singh, Fuqian Yang

Chemical and Materials Engineering Faculty Publications

Strained semiconductor quantum wells have been an active area of research for more than three decades. However, a major part of the reported literature has shown a core focus on the theoretical and experimental investigations of their energy band structures under different internal and external perturbations, taking strain parameters as the basis and studying their resulting effects on various optoelectrical properties of the strained quantum wells. However, since stress parameters can be measured more easily and with an enhanced level of accuracy compared to strain parameters, developing a stress-based analytical framework offers distinct advantages. This study focuses on the theoretical …

Duration And Properties Of The Embedded Phase Of Star Formation In 37 Nearby Galaxies From Phangs-Jwst, Lise Ramambason, Mélanie Chevance, Jaeyeon Kim, Francesco Belfiore, J. M. Diederik Kruijssen, Andrea Romanelli, Amirnezam Amiri, Médéric Boquien, Ryan Chown, Daniel A. Dale, Simthembile Dlamini, Oleg V. Egorov, Ivan Gerasimov, Simon C.O. Glover, Kathryn Grasha, Hamid Hassani, Hwihyun Kim, Kathryn Kreckel, Hannah Koziol, Adam K. Leroy, José Eduardo Méndez-Delgado, Justus Neumann, Lukas Neumann, Hsi An Pan, Debosmita Pathak, Karin Sandstrom, Sumit K. Sarbadhicary, Eva Schinnerer, Jiayi Sun, Jessica Sutter, David A. Thilker, Leonardo Ubeda

Physics and Astronomy Faculty Publications

Light reprocessed by dust grains emitting in the infrared enables the study of the physics at play in dusty embedded regions, where ultraviolet and optical wavelengths are attenuated. Infrared telescopes such as JWST have made it possible to study the earliest feedback phases, when stars are shielded by cocoons of gas and dust. Comprehending this phase is crucial for unravelling the effects of feedback from young stars that leads to their emergence and the dispersal of their host molecular clouds. Here we show that the transition from the embedded to the exposed phase of star formation is short (< 4 Myr) and sometimes almost absent (< 1 Myr) across a sample of 37 nearby star-forming galaxies covering a wide range of morphologies, from massive barred spirals to irregular dwarfs. The short duration of the dust-clearing timescales suggests a predominant role of pre-supernova feedback mechanisms in revealing newborn stars, confirming previous results on smaller samples and allowing, for the first time, a statistical analysis of their dependencies. We find that the timescales associated with mid-infrared emission at 21 μm, tracing a dust-embedded feedback phase, are controlled by a complex interplay between giant molecular cloud properties (masses and velocity dispersions) and galaxy morphology. We report relatively longer durations of the embedded phase of star formation in barred spiral galaxies, while this phase is significantly reduced in low-mass irregular dwarf galaxies. We discuss tentative trends with gas-phase metallicity, which may favor faster cloud dispersal at low metallicities.

Holographic Duality From Howe Duality, Anatoly Dymarsky, Johan Henriksson, Brian Mcpeak

Physics and Astronomy Faculty Publications

We discuss the holographic correspondence between 3d “Chern-Simons gravity” and an ensemble of 2d Narain code CFTs. Starting from 3d abelian Chern-Simons theory, we construct an ensemble of boundary CFTs defined by gauging all possible maximal subgroups of the bulk one-form symmetry. Each maximal non-anomalous subgroup is isomorphic to a classical even self-dual error-correcting code over ℤ_p × ℤ_p, providing a way to define a boundary “code CFT.” The average over the ensemble of such theories is holographically dual to Chern-Simons gravity, a bulk theory summed over 3d topologies sharing the same boundary. In the case of …

A Comparison Of Time-Dependent Cloudy Astrophysical Code Simulations With Experimental X-Ray Spectra From Kev Laser-Generated Argon Plasmas, N. Rathee, F. P. Keenan, R. J. R. Williams, Gary Ferland, S. J. Rose, S. White, D. Riley

Physics and Astronomy Faculty Publications

We have generated strongly photoionized Ar plasmas in experiments designed to use primarily X-ray l-shell line emission generated from Ag foils irradiated by the VULCAN high-power laser at the UK Central Laser Facility. The principle of the experiment is that use of line emission rather than the usual sub-keV quasi-blackbody source allows keV radiation to play a more dominant role compared to softer X-rays and thus mimic the effect of a blackbody with a higher effective spectral temperature. Our aim is to reproduce in the laboratory the extreme photoionization conditions found in accretion-powered astrophysical sources. In this paper, we compare …

Deep Learning-Based Quantification Of Tall Fescue Abundance In Pastures, Rose E. Binkley, Samuel R. Revolinski, Echo Elizabeth Gotsick, Ray Smith, Zeya Wang, Katsutoshi Mizuta

Plant and Soil Sciences Faculty Publications

Accurate and rapid measurement of tall fescue abundance is essential for efficient forage management and mitigating livestock exposure to potential endophyte-related toxicity. Traditional visual estimation methods are labor-intensive and are subject to change depending on the observer doing the calculations, which limits their scalability and consistency. This study explores the application of deep learning techniques to automate and improve the classification of tall fescue abundance across pasture systems in Kentucky. Ground-truth abundance classes were evaluated using one of the traditional methods with occupancy grid and compared against estimates derived from red-green-blue images. Two convolutional neural network architectures, YouOnlyLookOnce (YOLO) and …

Elevating Teacher Agency In School Decision-Making Through Trust-Building: Applying Appreciative Inquiry Within A Mixed Methods Action Research Framework, Alison S. Bellamy

University of Kentucky Doctoral Dissertations

This mixed methods action research (MMAR) study examined how Appreciative Inquiry–based professional learning influenced relational trust, teacher voice, and teacher agency in elementary school decision-making within New Hanover County Schools. Grounded in Teacher Agency Theory, Distributed Leadership Theory, and Appreciative Inquiry, the study addressed the gap between teachers’ perceptions of trust and their opportunities to influence school-level decisions. The study was conducted across three mid-quintile elementary schools using a concurrent QUAN–QUAL design. Quantitative data was collected through pre- and post-intervention relational trust surveys. Qualitative data included focus groups, participant reflections, field notes, and collaborative dialogue from two professional learning sessions …

Coupling Liquid Chromatography To Orbitrap Isotope Ratio Mass Spectrometry: Overcoming Isotope Effects Of Chromatography And Amount-Dependency By Peak Homogenization, Aoife Canavan, Leonhard Prechtl, Habib Al-Ghoul, Nils Kuhlbusch, Andrea M. Erhardt, Martin Elsner

Earth and Environmental Sciences Faculty Publications

Electrospray ionization Orbitrap mass spectrometry (ESI-Orbitrap-MS) has recently proven to be a powerful tool for compound- and position-specific stable isotope analysis, targeting isotopologues of multiple elements (H, C, N, O, S) in polar analytes. However, studies have so far mainly focused on pure analyte solutions via direct infusion. Here, we present the online coupling of liquid chromatography (LC) to ESI-Orbitrap-MS for stable isotope analysis of sulfamethoxazole (SMX), a synthetic antimicrobial, used as a model compound. Our study explored the fidelity of isotope values with two strategies for capturing and broadening chromatographic peaks after LC. When capturing the target analyte in …

Artificial Intelligence Methods For Circadian Rhythm Recovery And Disease Identification From High-Dimensional Omics Data, Aram Ansary Ogholbake

Theses and Dissertations--Computer Science

High-throughput transcriptomic and proteomic technologies have enabled opportunities for studying biological processes and disease mechanisms. However, extracting meaningful biological information from these high-dimensional datasets remains challenging due to limited sample sizes, biological heterogeneity, measurement noise, and the absence of biological annotations. In particular, many molecular datasets lack temporal information required for circadian analysis, making the study of circadian rhythms difficult. Moreover, disease diagnosis and biomarker discovery from transcriptomic data often rely on complex machine learning models whose predictions are difficult to interpret and may not generalize well across independent datasets and experimental platforms. These limitations motivate the development of artificial …

Accelerator Based Fusion Reactor With Magnetic Mirror, Keh-Fei Liu

Physics and Astronomy Faculty Publications

We consider an implementation of the novel accelerator-based fusion reactor scheme using a setup in which ion and electron beams are injected into the end openings of an axisymmetric magnetic mirror. While the magnetic mirror ensures transverse confinement of the plasma, the injected beams contribute to axial confinement, thereby extending the overall plasma lifetime. The ion beam energy is initially set above the resonance region of the fusion reactions, allowing fusion to occur both via resonance and thermal mechanisms as the beam slows down to the plasma temperature. Beam energy loss (stopping power) contributes to plasma heating, offsetting radiative losses …

Dynamical Phases Of Higher Dimensional Floquet Cfts, Diptarka Das, Sumit R. Das, Arnab Kundu, Krishnendu Sengupta

Physics and Astronomy Faculty Publications

This paper investigates the dynamical phases of Floquet Conformal Field Theories (CFTs) in space-time dimensions greater than two. Building upon our previous work which introduced quaternionic representations for studying Floquet dynamics in higher-dimensional CFTs, we now explore more general square pulse drive protocols that go beyond a single SU(1,1) subgroup. We demonstrate that, for multi-step drive protocols, the system exhibits distinct dynamical phases characterized by the nature of the eigenvalues of the quaternionic matrix representing time evolution in a single cycle, leading to different stroboscopic responses. Our analysis establishes a fundamental geometric interpretation where these dynamical phases directly correspond to …

Emission-Line Diagnostics At Z ≳ 2: A Probe Of The Ionizing Spectrum And Α-Enhancement Beyond Cosmic Noon, Leonardo Clarke, Natalie Lam, Alice E. Shapley, Michael W. Topping, Gabriel B. Brammer, Ryan L. Sanders, Naveen Reddy, Shreya Karthikeyan

Physics and Astronomy Faculty Publications

We analyze several key rest-optical emission-line ratios in a sample of 828 galaxies as well as composite spectra from JADES DR3 in the range 1.4 <  z <  7. These emission-line ratios include: [O iii]λ5008/Hβ, [N ii]λ6585/Hα, [S ii]λλ6718, 6733/Hα, [O i]λ6302/Hα, O32, R23, Ne3O2, and RO2Ne3. We find evidence for a harder ionizing spectrum at z ∼ 3.5 compared to z ∼ 2 at fixed gas-phase metallicity, resulting in a pronounced shift in the star-forming galaxy locus on the [N ii]/Hα Baldwin-Phillips-Terlevich (BPT) diagram and the O32 versus R23 diagram. At …

Aster Remote Sensing Satellite Imagery For Regional Mineral Mapping In The Mcmurdo Dry Valleys, South Victoria Land, Antarctica, Khurram Riaz, Amin Beiranvand Pour, Jabar Habashi, Aidy M. Muslim, Iman Masoumi, Ali Moradi Afrapoli, Mazlan Hashim, Kamyar Mehranzamir, Farshid Sattari

Mining Engineering Faculty Publications

The McMurdo Dry Valleys (DVs) of South Victoria Land, Antarctica, constitute the largest ice-free region on the continent and one of Earth’s most Mars-analog environments. Their hyper-arid polar desert conditions offer a unique setting for investigating surface weathering and mineralogical processes under extreme climates. This study presents the first regional-scale mapping of alteration and crystalline weathering minerals across the McMurdo DVs. It uses Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) multispectral data; visible and near-infrared (VNIR) and shortwave infrared (SWIR) bands were analyzed through a Spectral Hourglass Workflow, endmember extraction, and spectral unmixing with Matched Filtering (MF) and Constrained …

Building Public Health Data Dashboards: Tutorial Playbook, Elwin Wu, Raymond Balise, Benjamin Katz, Daniel R. Harris, Matthew Bullard, Naleef Fareed, Marc Larochelle, Jennifer Villani

Institute for Biomedical Informatics Faculty Publications

Public health data dashboards have substantial potential to improve transparency, understanding, and decision-making at multiple levels, from individuals to public health practitioners and policymakers. However, creating effective dashboards presents many challenges. In this case-based tutorial on public health dashboard development, we share lessons learned from our experience developing data dashboards for the HEALing Communities Study (HCS), a National Institutes of Health (NIH)–funded, community-engaged intervention to deploy evidence-based practices to reduce opioid overdose deaths in 67 communities across 4 states. We present key decision points dashboard teams must address, along with the major considerations and trade-offs that shaped our approach. First, …

Assessing Radio Transmitter Weight Effect And Evaluation Of Northern Bobwhite Chick Survival In Coastal North Carolina, Autumn S. Randall, Theron M. Terhune Ii, Matthew T. Springer, Darin J. Mcneil

Forestry and Natural Resources Faculty Publications

Studies on the earliest life stages are essential to our ecological understanding of avian demography; however, monitoring technologies that allow tracking of small birds are still limited in a variety of ways. One critical limitation, until recently, has been the development of methods for attaching transmitters to young birds with precocial development (e.g., Galliformes, Charadriiformes, etc.). The modified suture technique offers a means to attach transmitters to precocial chicks while accommodating rapid growth characterized by birds with precocial young. Although the sutured transmitter method was developed for northern bobwhite (Colinus virginianus) chicks, there remain key unknowns regarding best …

Aggregation Bias In Multi-Industry Economic Contribution Analysis: The Case Of Kentucky Forest Sector, Domena A. Agyeman, Thomas Ochuodho, Omkar Joshi

Forestry and Natural Resources Faculty Publications

Closely related industries are often aggregated in US forest sector economic contribution analysis, yet the choice of aggregation scheme can influence results. The Impact Analysis for Planning (IMPLAN) system is the most widely applied input–output model for forest economic contribution analysis in the US. In IMPLAN, the level of industry aggregation determines which inter-industry transactions are restricted, thereby influencing the magnitude of estimated indirect and induced effects. Although IMPLAN practitioners can model individual industries to avoid aggregation bias, they must still decide whether to analyze forest industries as a single group, as traditional subsectors, or individually. This decision can alter …

Effects Of Headwater Wetland Restoration On The Demography, Fecundity And Ecology Of The U.S. Federally Threatened White Fringeless Orchid (Platanthera Integrilabia) In The Cumberland Plateau Of Kentucky, Tara R. Littlefield, Catherine Hoy, Christopher Barton

Forestry and Natural Resources Faculty Publications

Wetland habitats represent a critical component of biodiversity hotspots that support numerous rare species, including terrestrial orchids. In North America, over half of all terrestrial orchids are found in wetlands, more than a quarter of which are now threatened with extinction (G1–G3). This concerning trend is exacerbated by a lack of information on effective restoration strategies aimed at orchids and other species that inhabit these areas. The white fringeless orchid, Platanthera integrilabia (Correll) Luer, the subject of this study, is restricted to mostly shaded wetland habitats along the Cumberland Plateau of the Appalachian Mountains and has suffered widespread declines due …

Balancing Face-To-Face And Digital Communication: The Role Of Relationship Maintenance In Dual-Earning Families, Tamara D. Afifi, America L. Edwards

Information Science Faculty Publications

This study examines how face-to-face (FtF) and computer-mediated communication (CMC) contribute to relationship maintenance and resilience in dual-earning families, a largely overlooked area in family communication research. Guided by the theory of resilience and relational load (TRRL), we test how ongoing FtF and CMC maintenance behaviors predicted well-being across a week among 62 families (i.e., two parents and one adolescent). Using a week-long daily diary and physiological measures (cortisol and IL-6 assays), we assess perceived stress, mental health, and loneliness. Findings suggest that both FtF and CMC maintenance are associated with lower stress and better well-being, with FtF showing somewhat …

Establishing A Public Health Surveillance System For The Opioid Crisis: The Experience Of The Healing Communities Study, Bridget Freisthler, Daniel J. Feaster, Charles Knott, Marc Larochelle, John Mccarthy, Svetla Slavova, Sharon L. Walsh, Jennifer Villani

Biostatistics Faculty Publications

Introduction: Efforts to reduce opioid overdose deaths in the United States have been stymied by the lack of timely and standardized population-level data for local, state, and national levels. The U.S. has a strong national need for linking opioid and other drug overdose surveillance data to service utilization data for overdose prevention and treatment to inform resource allocation and response planning.

Methods: We provide insight on the challenges of identifying, obtaining, and harmonizing administrative outcome data across four states using the collective experience from the HEALing Communities Study to test a community-engaged, data-driven, population-level intervention to reduce opioid overdose deaths. …