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Caffeine Consumption Patterns And Beliefs Of College Freshmen, Gary Eugene Mcilvain

University of Kentucky Doctoral Dissertations

Recently, energy drinks that contain high caffeine content without any age restrictions for purchase, have been introduced into the U.S. market. Caffeine consumption in the U.S. has increased dramatically, resulting in an increase in emergency room visits and calls to poison control centers. This increase in energy drink consumption, along with the traditional coffees, teas, and soft drinks that people consume regularly, have pushed caffeine consumption to new highs in a multi-billion dollar market.

The purpose of this study was to determine (1) the amount of caffeine consumed by a sample of freshmen students at Marshall University, (2) their beliefs …

Rapid Phase Adjustment Of Melatonin And Core Body Temperature Rhythms Following A 6-H Advance Of The Light/Dark Cycle In The Horse, Barbara A. Murphy, Jeffrey A. Elliott, Dawn R. Sessions, Mandi M. Vick, Erin L. Kennedy, Barry P. Fitzgerald

Veterinary Science Faculty Publications

BACKGROUND: Rapid displacement across multiple time zones results in a conflict between the new cycle of light and dark and the previously entrained program of the internal circadian clock, a phenomenon known as jet lag. In humans, jet lag is often characterized by malaise, appetite loss, fatigue, disturbed sleep and performance deficit, the consequences of which are of particular concern to athletes hoping to perform optimally at an international destination. As a species renowned for its capacity for athletic performance, the consequences of jet lag are also relevant for the horse. However, the duration and severity of jet lag related …

Role Of Calcium And Nitric Oxide Synthase (Nos) In Brain Mitochondrial Dysfunction, Vidya Nag Nukala

Theses and Dissertations--Neuroscience

Mitochondria are essential for promoting cell survival and growth through aerobic metabolism and energy production. Mitochondrial function is typically analyzed using mitochondria freshly isolated from tissues and cells because they yield tightly coupled mitochondria, whereas those from frozen tissue can consist of broken mitochondria and membrane fragments. A method, utilizing a well-characterized cryoprotectant such as dimethyl sulfoxide (DMSO), is described. Such mitochondria show preserved structure and function that presents us with a possible strategy to considerably expand the time-frame and the range of biochemical, molecular and metabolic studies that can be performed without the constraints of mitochondrial longevity ex vivo …

Role Of Conduction In The Genesis Of Alternans Of Action Potential Duration In A Simulated One Dimensional Fiber, Sanjiv Ramalingam

University of Kentucky Master's Theses

Ventricular fibrillation is one of the leading causes for Sudden Cardiac Death and is characterized by multiple activation wavefronts. Multiple activation wavefronts originate from a reentrant circuit which requires the presence of a unidirectional block in the path of a propagating excitation wave. It has been proposed that at the cellular level beat to beat alternation in the action potential duration at rapid pacing rates can result in a conduction block. Various mechanisms have been postulated to show the mechanisms of alternans. We use simulated activation in a one dimensional tissue fiber to show the existence of a new mechanism …

Oxpat/Pat-1 Is A Ppar-Induced Lipid Droplet Protein That Promotes Fatty Acid Utilization, Nathan E. Wolins, Benjamin K. Quaynor, James R. Skinner, Anatoly Tzekov, Michelle A. Croce, Matthew C. Gropler, Vijayalakshmi Varma, Aiwei Yao-Borengasser, Neda Rasouli, Philip A. Kern, Brian N. Finck, Perry E. Bickel

Clinical and Translational Science Faculty Publications

Lipid droplet proteins of the PAT (perilipin, adipophilin, and TIP47) family regulate cellular neutral lipid stores. We have studied a new member of this family, PAT-1, and found that it is expressed in highly oxidative tissues. We refer to this protein as "OXPAT." Physiologic lipid loading of mouse liver by fasting enriches OXPAT in the lipid droplet tissue fraction. OXPAT resides on lipid droplets with the PAT protein adipophilin in primary cardiomyocytes. Ectopic expression of OXPAT promotes fatty acid-induced triacylglycerol accumulation, long-chain fatty acid oxidation, and mRNAs associated with oxidative metabolism. Consistent with these observations, OXPAT is induced in mouse …

Loss Of Sympathetic Control Of Cardiovascular Function Following Spinal Cord Injury, Charles Everett Hogancamp Ii

University of Kentucky Master's Theses

Cardiovascular control in the human is significantly impaired after spinal cord injury(SCI) having a direct effect on the sympathetic nervous system (SNS) causing an inability toregulate vasoconstriction below the level of the lesion. The effects of SCI on the two majorcomponents of blood pressure regulation, control of plasma volume and neural control of theheart and peripheral vasculature are poorly understood. In particular, no index to diagnosedisorders to autonomic control of the heart and vasculature has been developed. The presentstudy primarily utilized noninvasively acquired, easily accessible variables that may havepromise as indicators of autonomic activity for assessing the level of autonomic …

The Meanings Of Underpants And Old Photographs: Notions Of Personhood And Pollution In The Estate Sale, Donna Foulk

University of Kentucky Master's Theses

In the estate sale, actors (shoppers and estate sale workers) form notions ofpersonhood and pollution through objects such as half-used bottles of perfume, floral dishes, and family photographs. Actors use these objects to create the gender, personality, religion, hobbies, and occupation of the objects' former owners. The context of the estate sale contributes to these notions of personhood. Estate sales usually occur after a death, almost everything this person has owned is priced for sale, and the estate sale is held within the house of the deceased.This study draws on Mary Douglas' work on pollution as "matter out of place." …

Entrainment Of Electrical Activation By Spatio-Temporal Distributed Pacing During Ventricular Fibrillation, Yiping Gu

University of Kentucky Master's Theses

Spatio-temporal variation in action intervals during ventricular fibrillation (VF) suggestthat the excitable gap may also be distributed spatio-temporally. The observation leadus to hypothesize that distributed pacing can be used to modify and entrain electricalactivation during VF. We tested this hypothesis using simulated VF and animal studies.

We simulated VF in a 400 by 400 cell matrix. Simulation results showed that activationpattern could be entrained using spatially distributed stimulation. Up to a certain limit,increasing stimulus strength and density led to improved entrainment. Best entrainmentwas obtained by pacing at a cycle length similar to the intrinsic cycle length.

In order to verify …

The Criminal Law Implications Of The Human Genome Project: Reimagining A Genetically Oriented Criminal Justice System, Steven I. Friedland

Kentucky Law Journal

No abstract provided.