Digital Commons Network^™

At The Heart Of Policies And Programs: Community College Faculty Members And Peer Mentors As Human Levers Of Retention, Kimberly Russell

Theses and Dissertations--Educational Policy Studies and Evaluation

Student attrition prior to the completion of a credential is an issue that has increasingly demanded the attention of stakeholders in higher education, particularly in the community college sector, in which less than half of all students complete a credential after six years. The costs of student attrition are high and widespread, ranging from the financial costs for institutions and federal and state governments to the personal and monetary costs paid by those students whose personal and professional goals are not achieved. With the ever-increasing focus on accountability for institutions of higher education and the growing movement toward performance-based funding, …

A Quasi-Experimental Study Of Middle Level Student Engineering Understanding Pre-And Post-Treatment, Emily Driessen

Theses and Dissertations--Science, Technology, Engineering, and Mathematics (STEM) Education

This qualitative quasi-experimental study analyzed middle-level students’ understanding of engineering before and after instruction. Students from four teachers were examined. Before and after instruction, all students completed the Draw an Engineer Test (DAET) and the Views of Nature of Engineering (VNOE) survey. Additionally, sixteen students (eight girls and eight boys) from each group (Treatment and Comparison) were interviewed before and after instruction. Findings revealed that after instruction (1) many students viewed engineers as makers/builders/workers (just as they did pre-instruction), however, the percentage of students who listed engineers as inventors, designers, and creators increased; (2) fewer students from both groups noted …

Improving Undergraduate Statistics Education: Educational Lessons From Two Pedagogical Experiments, Anushka Karkelanova

Theses and Dissertations--Curriculum and Instruction

The ultimate goal of statistics education is to create a statistically literate society in which people can appropriately use statistical thinking. Although the need to improve the teaching of introductory statistics courses is not a new one, with increased demand on these courses, there has been constant effort to seek out better ways of teaching these courses. The University of Kentucky (UK) began a reform of its general education program in November 2005. Thinking and reasoning are the central themes of this well-designed general education curriculum.

The main goal of this dissertation is to fill in some gaps in the …

Leadership Development In Physical Therapy: Moving Toward A Community Of Transformative Practitioners, Kerry Cronin Mallini

Theses and Dissertations--Educational Leadership Studies

Physical therapy as an emerging profession is committed to establishing its identity and solidifying its role as a leader in health care. With expertise in human movement, wellness, and disease prevention, physical therapists possess invaluable knowledge and skill to influence public health and enhance patient recovery without increasing cost. Physical therapists have the opportunity to transform the delivery of public health services to meet current and future needs. A major challenge, however, is a dearth of leadership development in preparation programs. Because most physical therapists have not received formal education or explicit training in leadership, a problem of practice exists. …

A Kentucky Pioneer In Music Therapy: An Oral History On The Life And Career Of Lorinda Jones, Emma Powers

Theses and Dissertations--Music

Lorinda Jones, MT-BC, is the longest practicing music therapist in Kentucky. She began her work as a music therapist in 1995 and built a private practice, which expanded over the course of the next 20 years to include services in 16 counties. Ms. Jones’ perspective on the growth of music therapy, both within the state and nationwide, as well as her extensive knowledge of Appalachian folk music, makes her an invaluable resource to Kentucky music therapists. The purpose of this study was to present a historical account of the life and career of Lorinda Jones, to gain her perspective on …

The Effectiveness Of Music Therapy Interventions With Persons Of Concern: An Integrative Review, Grace Lauzon

Theses and Dissertations--Music

Immigrants, refugees, asylum seekers, internally displaced persons, and stateless persons, collectively known as “persons of concern,” often have unmet mental health and wellness needs as a result of trauma. With a diverse variety of interventions and approaches, the use of music therapy has the potential to meet the needs of persons of concern. In the present study, the researcher conducted an integrative review to examine the use of music therapy with persons of concern. After conducting a hand-search of music therapy journals and an advanced keyword search through internet databases, the researcher found 17 studies that met inclusion criteria. There …

A Singer’S Stress: Yoga And Meditation Techniques In The Collegiate Voice Studio, Zackery David Morris

Theses and Dissertations--Music

Often neglected in voice study is the understanding that a singer’s instrument lives in his/her body and therefore cannot be packed away like other musical objects. Yoga and mindfulness compliment the belief of a whole body instrument. Data gathered on college campuses report that stress and anxiety are on the rise, thus reinforcing the need for MBSR and yoga as beneficial and proven tools for stress relief. The current state of research in the realm of mental health in colleges merits the study of a cohesive layout of these exercises and their expected outcomes in singing as well as stress …

Factors Influencing Music Therapy Career Choice In The United States: A Study Of Student Values And Expectancies, Margaret R. Scheppmann

Theses and Dissertations--Music

The understanding of why students decide to become music therapists is valuable information for music therapy educators and policy makers and published information is lacking. The use of expectancy-value theory provides a framework to understand student choices. Researchers can better understand why students purse a career in music therapy by examining students’ abilities, beliefs, expectancies, and values related to the choice. The purpose of this study was to examine why current undergraduate and equivalency students want to be music therapists. Music therapy students (N = 129) throughout the United States provided insight into their decision to become music therapists …

Morten Lauridsen’S Choral Cycle, Nocturnes: A Conductor’S Analysis, Margaret B. Owens

Theses and Dissertations--Music

Morten Lauridsen is one of the most prolific composers of choral music in the 20th and 21st centuries. His characteristic tone is both readily identifiable and timeless. Works such as Lux Aeterna, Les Chansons des Roses, “Sure on this Shining Night” (from Nocturnes) , and “O magnum mysterium” have solidified his place as one of the most important compositional voices in modern choral music.

Lauridsen’s most often-performed choral works have been individual movements excerpted from his larger choral works, due to their accessibility for advanced high school and collegiate choirs. For example, the popular “Dirait-on” comes from the …

A Repurposed Narrative: Mary Rowlandson’S Narrative And Pre-Revolutionary Sentiment, Steven F. Thomas

Theses and Dissertations--English

Leading into the American Revolution, Puritan captivity narratives gained a resurgent popularity as nationalized sentiment burned towards political upheaval. Mary Rowlandson’s Narrative (1682) was reprinted six times between 1770-1776, signifying an incredible interest in Puritan stories that seemed to antithetically inspire a progressive and radical revolution against England. The Sovereignty and Goodness of God or A True History of the Captivity and Restoration of Mrs. Mary Rowlandson enhanced an already fervent revolutionary sentiment, transforming a seemingly straightforward captivity narrative into a totem meant to represent the oppressive struggle between England and her most coveted colony.

Such a literary revival taps …

Essays On Financial Incentives, Tyson D. Van Alfen

Theses and Dissertations--Finance and Quantitative Methods

In my first chapter, I use a novel dataset of customer reviews from Amazon.com to study the impact of managerial myopia on product market reputation. Using exogenous variation due to the timing of CEO equity vesting events, I show that short-term incentive shocks predict declines in reputation. A changing product market lineup and a deterioration of existing products are two mechanisms through which reputation is affected. The effect is larger when the CEO has other short-term concerns and when the firm has a low reputation in the product market. However, higher advertising expenses mitigate the negative reputational effect among consumers. …

The Effects Of Natural Resource Dependence And Democracy On The Incremental Budgeting Theory And Punctuated Equilibrium Within A Budgetary Context, Barrak Ghanim Algharabali

Theses and Dissertations--Public Policy and Administration

I contribute to the literature by providing additional factors that could affect the incremental budgeting theory and punctuated equilibrium theory (PET) within a budgetary context. Because of the fluctuation in the price of natural resources, I argue that dependence on natural resources could lead to less stable budgets than ones not dependent on natural resources. I also argue that democracy is another source that leads to stability in the budget, relative to countries that are not democratic. I theorize that countries with no democracy and heavy dependence on natural resources will have budgets with more volatility than the rest of …

Three Essays On Municipal Structure And Government Fiscal Management Outcomes, Wenchi Wei

Theses and Dissertations--Public Policy and Administration

This dissertation aims to reclassify municipal structures of the U.S. municipalities and investigates the effect of municipal structures on government fiscal management outcomes, including fiscal conditions and fiscal slack balances. This dissertation is comprised of four chapters. The first chapter briefly introduces, and each of the remaining three is an independent research article. The second chapter investigates seven essential structural characteristics of the U.S. municipalities and constructs a municipal structure political-administrative index. It then examines the determinants of municipal structures on a political-administrative dimension. The empirical results show that municipal structure choices are statistically significantly associated with citizens’ socioeconomic and …

The Decision To Decentralize Good Provision In The United States: A Study In Clean Energy Policy, Whitney Michelle Davis

Theses and Dissertations--Public Policy and Administration

Normative economic theory provides justification for at least partially centralized renewable energy provision due to the large, positive externalities associated with renewable energy production. However, the United States is one of the few countries without centralized renewable energy policy. Instead, the federal government actively chooses decentralized renewable energy provision by using fiscal transfers to support subnational renewable energy development. This dissertation explores why U.S. legislators choose decentralized renewable energy provision by asking two primary questions. First, what is the motivation for using federal fiscal transfers for decentralized renewable energy output considering what we know about positive spillovers and market failure …

Students On The Margins: Intersectionality And College Campus Sexual Assault, Margaret Irene Campe

Theses and Dissertations--Sociology

This three-paper dissertation quantitatively identifies and examines three different substantive areas using data from the American College Health Association’s Fall of 2016 National College Health Assessment (ACHA-NCHA). Specific areas of inquiry include, marginalized populations and college campus sexual assault, intersectional analyses of risk factors for college campus sexual assault, and drinking protective behavioral strategies as prevention tools for college campus sexual assault. Paper one, titled, “College Campus Sexual Assault and Students with Disabilities,” explores a particular marginalized group of students that have been largely left out of college campus sexual assault studies: female college students with disabilities. The logistic regression …

Polysubstance Opioid Use In A Justice-Involved Population: An Analysis Of Patterns And Reentry Outcomes, Amanda Marie Bunting

Theses and Dissertations--Sociology

The public health crisis surrounding opioid use is pronounced among justice-involved populations, who face high rates of overdose mortality as well as HIV, and hepatitis C due to injection drug use. The majority of opioid-related overdoses are due to polysubstance use (PSU), and a better understanding of the prevalence and patterns of PSU are necessary in order to inform interventions. This dissertation project has three aims: (1) understand the patterns of opioid PSU among a justice-involved population, (2) identify PSU patterns most at-risk for post-release relapse, and (3) examine engagement in post-release health service utilization. Post-release aims are guided by …

Automatic 13C Chemical Shift Reference Correction Of Protein Nmr Spectral Data Using Data Mining And Bayesian Statistical Modeling, Xi Chen

Theses and Dissertations--Molecular and Cellular Biochemistry

Nuclear magnetic resonance (NMR) is a highly versatile analytical technique for studying molecular configuration, conformation, and dynamics, especially of biomacromolecules such as proteins. However, due to the intrinsic properties of NMR experiments, results from the NMR instruments require a refencing step before the down-the-line analysis. Poor chemical shift referencing, especially for ¹³C in protein Nuclear Magnetic Resonance (NMR) experiments, fundamentally limits and even prevents effective study of biomacromolecules via NMR. There is no available method that can rereference carbon chemical shifts from protein NMR without secondary experimental information such as structure or resonance assignment.

To solve this problem, we …

Semisynthetic Aurones: A Family Of Newly Discovered Tubulin Inhibitors As Antineoplastic Agents, Yanqi Xie

Theses and Dissertations--Molecular and Cellular Biochemistry

Aurones belong to an uncommon class of plant flavonoids that provide the bright yellow coloration of some ornamental flowers and that possess a range of biological activities. Structure-activity relationships (SAR) in the aurone pharmacophore identified heterocyclic variants of the (Z)-2-benzylidene-6-hydroxybenzofuran-3(2H)-one scaffold that possessed low nanomolar in vitro potency in cell proliferation assays using various cancer cell lines, in vivo potency in prostate cancer PC-3 xenograft and zebrafish models, selectivity for the colchicine-binding site on tubulin, and absence of appreciable toxicity. Among the biologically active analogs developed in the course of this dissertation work were (Z …

Computational Tools For The Dynamic Categorization And Augmented Utilization Of The Gene Ontology, Eugene Waverly Hinderer Iii

Theses and Dissertations--Molecular and Cellular Biochemistry

Ontologies provide an organization of language, in the form of a network or graph, which is amenable to computational analysis while remaining human-readable. Although they are used in a variety of disciplines, ontologies in the biomedical field, such as Gene Ontology, are of interest for their role in organizing terminology used to describe—among other concepts—the functions, locations, and processes of genes and gene-products. Due to the consistency and level of automation that ontologies provide for such annotations, methods for finding enriched biological terminology from a set of differentially identified genes in a tissue or cell sample have been developed to …

Computational Tools For The Untargeted Assignment Of Ft-Ms Metabolomics Datasets, Joshua Merritt Mitchell

Theses and Dissertations--Molecular and Cellular Biochemistry

Metabolomics is the study of metabolomes, the sets of metabolites observed in living systems. Metabolism interconverts these metabolites to provide the molecules and energy necessary for life processes. Many disease processes, including cancer, have a significant metabolic component that manifests as differences in what metabolites are present and in what quantities they are produced and utilized. Thus, using metabolomics, differences between metabolomes in disease and non-disease states can be detected and these differences improve our understanding of disease processes at the molecular level. Despite the potential benefits of metabolomics, the comprehensive investigation of metabolomes remains difficult.

A popular analytical technique …

The Functional Role Of Rna Binding Protein Rbms3 As A Tumor Promoter In Triple-Negative Breast Cancer Cells, Yuting Zhou

Theses and Dissertations--Molecular and Cellular Biochemistry

RBMS3 belongs to the family of c-myc gene single-strand binding proteins (MSSPs) that play important roles in transcriptional regulation. Here, we show that RBMS3 functions as a tumor promoter in triple-negative breast cancer (TNBC), a highly aggressive BC subtype. Analysis of RBMS3 expression shows that RBMS3 is upregulated at both mRNA and protein levels in TNBC cells. Functionally, overexpression of RBMS3 increases cell migration, invasion and cancer stem cell (CSC) behaviors. Moreover, RBMS3 induces expression of epithelial-mesenchymal transition (EMT) and CSC markers. Conversely, loss of RBMS3 in TNBC BT549 cells inhibits cell proliferation, migration and mesenchymal phenotype. Correlation analysis shows …

The Effects Of A Ketone Body On Synaptic Transmission, Alexandra Elizabeth Stanback

Theses and Dissertations--Biology

The ketogenic diet is commonly used to control epilepsy, especially in cases when medications cannot. The diet typically consists of high fat, low carb, and adequate protein and produces a metabolite called acetoacetate. Seizure activity is characterized by glutamate excitotoxicity and therefore glutamate regulation is a point of research for control of these disorders. Acetoacetate is heavily implicated as the primary molecule responsible for decreasing glutamate in the synapse; it is believed that acetoacetate interferes with the transport of glutamate into the synaptic vesicles. The effects on synaptic transmission at glutamatergic synapses was studied in relation to the ketogenic diet …

A Descriptive Analysis Of Health Influencer Videos On Youtube In The Ostomy Community, Sarah Irenke Sophia Bell

Theses and Dissertations--Communication

The expansion of YouTube into the mainstream media and its place as the second most-used website in the world makes it a prime place for health information seeking. However, content can be created and uploaded by anyone and thus, the threat of misinformation on YouTube is high. Medical researchers have established that videos created by health professionals on YouTube promote accurate information whereas videos by non-professionals promote generally inaccurate or misleading information. Yet, videos created by non-professionals have more views and higher relevance rankings on YouTube. To begin to understand this phenomenon, a descriptive study is used to lay a …

Navigating The Michelle P. Waiver: A Narrative Examination Of The Impact Of Parent Caregiver-Related Uncertainty And Decision Making For Children With Disabilities, Whittney H. Darnell

Theses and Dissertations--Communication

The Michelle P. Waiver (MPW) is the primary means of health insurance for more than 10,000 people in the state of Kentucky. The waiver is especially popular among families with young children with disabilities because it is robust in its benefit offerings and also one of the few Medicaid resources that does not include parental income as a qualifying factor in eligibility. Through the waiver, children receive a medical card as well as additional coverage for medical expenses that fall beyond the scope of traditional health insurance. For these young children to gain access to the comprehensive offerings of the …

Multigenerational Genomic And Epigenetic Effects Of Manufactured Silver Nanomaterials In Caenorhabditis Elegans, Anye Wamucho

Theses and Dissertations--Toxicology and Cancer Biology

There has been an increase in the incorporation of silver nanomaterials into consumer products due to their antimicrobial properties. Therefore there is potential for silver nanoparticles (Ag-NPs) to leach out into the environment during different life-cycle stages of these nanomaterial-containing products. Concern about the toxicity of Ag-NPs has led to investigations into their toxic effects on a variety of organisms mainly using acute and sub-chronic, single-generation exposures. The focus of this project was to understand the effects of long-term continuous multigenerational exposure to AgNO₃ and Ag-NPs in both pristine and environmentally transformed forms, on the model organism, Caenorhabditis elegans …

P4ha1 Is A New Regulator Of The Hif-1 Pathway In Breast Cancer, Ren Xu

Markey Cancer Center Faculty Publications

Hypoxia-Inducible Factor (HIF)-1 is a transcription factor that plays the key role in response to low oxygen concentrations, or hypoxia. Activation of the HIF-1 pathway is not only crucial for normal tissue development and function, but also involved in disease progression, such as cancer. Cancer cells proliferate rapidly in solid tumors, and thus, solid tumors consume much more oxygen and nutrients than normal tissue and generate oxygen tension. It is well established that oxygen tension in solid tumor tissue induces the aberrant activation of the HIF-1 pathway, and subsequently promotes angiogenesis and tumor progression. Breast cancer is a heterogeneous disease …

Weld Penetration Identification Based On Convolutional Neural Network, Chao Li

Theses and Dissertations--Electrical and Computer Engineering

Weld joint penetration determination is the key factor in welding process control area. Not only has it directly affected the weld joint mechanical properties, like fatigue for example. It also requires much of human intelligence, which either complex modeling or rich of welding experience. Therefore, weld penetration status identification has become the obstacle for intelligent welding system. In this dissertation, an innovative method has been proposed to detect the weld joint penetration status using machine-learning algorithms.

A GTAW welding system is firstly built. Project a dot-structured laser pattern onto the weld pool surface during welding process, the reflected laser pattern …

Curricular Optimization: Solving For The Optimal Student Success Pathway, William G. Thompson-Arjona

Theses and Dissertations--Electrical and Computer Engineering

Considering the significant investment of higher education made by students and their families, graduating in a timely manner is of the utmost importance. Delay attributed to drop out or the retaking of a course adds cost and negatively affects a student’s academic progression. Considering this, it becomes paramount for institutions to focus on student success in relation to term scheduling.

Often overlooked, complexity of a course schedule may be one of the most important factors in whether or not a student successfully completes his or her degree. More often than not students entering an institution as a first time full …

Evaluation Of The Effect Of Milner-Fenwick Video-Based Education And Teach-Back On Knowledge Acquisition In Atrial Fibrillation Patients, Melissa Czarapata

DNP Projects

PURPOSE: The purpose of this study was to evaluate if video education impacts knowledge acquisition and health literacy in patients with atrial fibrillation. METHODS: This study employed a descriptive, pretest-posttest single site comparative design. Baseline health literacy was assessed before video education was completed using the Atrial Fibrillation Knowledge scale. Health literacy regarding atrial fibrillation was again assessed for the same participants immediately after video education was completed and again in 7 to 10 days through the use of the Atrial Fibrillation Knowledge scale and teach-back questions. RESULTS: There was no statistical significance found when comparing scores before and after …

The Effect Of Narrative Medicine Combined With Medication Assisted Treatment On Decreasing The Desire To Use Intravenous Substances In Hospitalized Patients With Infective Endocarditis, Paula Works

DNP Projects

Substance abuse is a significant problem that spans the nation. Of particular concern is the growing population of patients at UK HealthCare who have endocarditis as a complication from IV substance abuse.

PURPOSE: The aims of this study were

1. To assess the effect of narrative medicine combined with MAT, compared to MAT alone, on desire to use in hospitalized patients with a history of IV substance use
2. To examine the changes in quality of life before and after the introduction of narrative medicine in hospitalized patients with a history of IV substance abuse using The Quality of Life Scale (QOLS). …