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Articles 661 - 690 of 18291
Full-Text Articles in Entire DC Network
Wage Enslavement: How The Tax System Holds Back Historically Disadvantaged Groups Of Americans, Goldburn P. Maynard Jr., David Gamage
Wage Enslavement: How The Tax System Holds Back Historically Disadvantaged Groups Of Americans, Goldburn P. Maynard Jr., David Gamage
Kentucky Law Journal
No abstract provided.
Inequality By Unnatural Selection: The Impact Of Tax Code Bias On The Racial Wealth Gap, Phyllis C. Tate
Inequality By Unnatural Selection: The Impact Of Tax Code Bias On The Racial Wealth Gap, Phyllis C. Tate
Kentucky Law Journal
No abstract provided.
Homeownership While Black: A Pathway To Plunder, Compliments Of Uncle Sam, Richard Winchester
Homeownership While Black: A Pathway To Plunder, Compliments Of Uncle Sam, Richard Winchester
Kentucky Law Journal
No abstract provided.
Table Of Contents For Volume 110, Issue 4, Kentucky Law Journal
Table Of Contents For Volume 110, Issue 4, Kentucky Law Journal
Kentucky Law Journal
No abstract provided.
Objective Deliberate Indifference Only: Pretrial Detainees' Fourteenth Amendment Substantive Due Process Rights Demand Protection In The Context Of Mental Illness And Substance Use Disorder, Jessica Lewis
Kentucky Law Journal
No abstract provided.
Rectifying The Safe Drinking Water Act And The Clean Water Act: Per- And Poly-Fluoroalkyl Substances (Pfas)—A Case Study, M. Elizabeth Goss
Rectifying The Safe Drinking Water Act And The Clean Water Act: Per- And Poly-Fluoroalkyl Substances (Pfas)—A Case Study, M. Elizabeth Goss
Kentucky Law Journal
No abstract provided.
The Fact-Finders' Dialectic: Beyond Rationalist Optimism And Realist Pessimism, Michael Head
The Fact-Finders' Dialectic: Beyond Rationalist Optimism And Realist Pessimism, Michael Head
Kentucky Law Journal
No abstract provided.
Chronic Pain And Subjective Memory Problems Are Dynamic Risk Factors For Functional Decline, Tyler R. Bell, Cynthia Felix, Nathalie Gider, George W. Rebok, Michael Crowe, Karlene Ball, Gail Wallace, Sheila Black, Kelsey R. Thomas, Katie M. Wheeler, Felix J. Kollasserry, Jeanine M. Parisi, Caitlin A. Northcutt
Chronic Pain And Subjective Memory Problems Are Dynamic Risk Factors For Functional Decline, Tyler R. Bell, Cynthia Felix, Nathalie Gider, George W. Rebok, Michael Crowe, Karlene Ball, Gail Wallace, Sheila Black, Kelsey R. Thomas, Katie M. Wheeler, Felix J. Kollasserry, Jeanine M. Parisi, Caitlin A. Northcutt
Epidemiology and Environmental Health Faculty Publications
Chronic pain is highly prevalent in older adults and is associated with elevated risk for disability and dementia. Subjective memory problems (SMPs) - self-rated memory difficulties - are also common and may serve as early indicators of functional decline. This study examined associations between SMPs and cognitive, physical, and psychosocial functioning among older adults with and without chronic pain. Data were drawn from 2365 participants in the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) study. Multilevel models assessed the impact of baseline and time-varying SMPs on cognitive performance (memory, reasoning, processing speed), physical function (mobility, grip strength, self-rated …
Performance Of Dried Blood Spot Cards For Serologic Detection Of Hpv16 Antibodies In Oropharyngeal Squamous Cell Carcinoma Patients, Maisha Maliha Rahman, Soma Bose, Li Chen, Jessica L. Burris, Rony Aouad, Susanne M. Arnold, Melvyn Yeoh, Birgitta Michels, Tim Waterboer, Krystle A. Lang Kuhs
Performance Of Dried Blood Spot Cards For Serologic Detection Of Hpv16 Antibodies In Oropharyngeal Squamous Cell Carcinoma Patients, Maisha Maliha Rahman, Soma Bose, Li Chen, Jessica L. Burris, Rony Aouad, Susanne M. Arnold, Melvyn Yeoh, Birgitta Michels, Tim Waterboer, Krystle A. Lang Kuhs
Epidemiology and Environmental Health Faculty Publications
Antibodies against the human papillomavirus type 16 (HPV16) E6 oncoprotein are promising biomarkers for the early detection of HPV-driven oropharyngeal squamous cell carcinoma (HPV+OPSCC). Standard serologic testing is challenging in underserved regions with high HPV+OPSCC incidence. Dried blood spot (DBS) cards offer a low-resource alternative but remain unevaluated for HPV antibody detection. A total of 25 OPSCC patients who provided paired serum (venipuncture) and DBS (finger-prick) samples were recruited from the University of Kentucky. HPV16 antibodies (L1, E1, E2, E4, E6, E7) were measured using multiplex serology, quantified as median fluorescence intensity (MFI) and dichotomized using established cutoffs. Correlation between …
Prenatal Cocaine Exposure, Perinatal Risks, And Mediators To Preadolescent Attention Deficit Hyperactivity Disorder (Adhd), Thitinart Sithisarn, Carla M. Bann, Barry Lester, Seetha Shankaran, Toni Whitaker, Rosemary D. Higgins, Henrietta Bada
Prenatal Cocaine Exposure, Perinatal Risks, And Mediators To Preadolescent Attention Deficit Hyperactivity Disorder (Adhd), Thitinart Sithisarn, Carla M. Bann, Barry Lester, Seetha Shankaran, Toni Whitaker, Rosemary D. Higgins, Henrietta Bada
Epidemiology and Environmental Health Faculty Publications
Highlights: What are the main findings? Prenatal cocaine exposure increases the risk of ADHD in preadolescence, with effects largely mediated through attention problems and impulsivity at 4–5 years of age. Male sex is an independent risk factor with a direct path to the ADHD diagnosis. What is the implication of the main finding? Screening for behavioral problems before 4 years of age in prenatal cocaine exposure would make possible early intervention to mitigate later diagnosis or severity of ADHD. Attention-deficit/hyperactivity disorder (ADHD) is the most common behavioral problem in children. Multiple risk factors, including prenatal substance exposure, have been associated …
The Neighborhoods Study, Grace C. George, Sarah A. Keller, Erin Abner, Sara Adar, Michael L. Alosco, Liana G. Apostolova, Kelly Bakulski, Lisa L. Barnes, James R. Bateman, Stuart Batterman, Thomas G. Beach, Barbara B. Bendlin, David A. Bennett, Tobey J. Betthauser, James Brewer, William Buckingham, Carmen I. Carrión, Joshua Chodosh, Suzanne Craft, Raina Croff, Anthony Fabio, Sarah Tomaszewski Farias, Eva L. Feldman, Felicia Goldstein, Stephen A. Goutman, Gina Green-Harris, Victor Henderson, Thomas K. Karikari
The Neighborhoods Study, Grace C. George, Sarah A. Keller, Erin Abner, Sara Adar, Michael L. Alosco, Liana G. Apostolova, Kelly Bakulski, Lisa L. Barnes, James R. Bateman, Stuart Batterman, Thomas G. Beach, Barbara B. Bendlin, David A. Bennett, Tobey J. Betthauser, James Brewer, William Buckingham, Carmen I. Carrión, Joshua Chodosh, Suzanne Craft, Raina Croff, Anthony Fabio, Sarah Tomaszewski Farias, Eva L. Feldman, Felicia Goldstein, Stephen A. Goutman, Gina Green-Harris, Victor Henderson, Thomas K. Karikari
Epidemiology and Environmental Health Faculty Publications
INTRODUCTION: The Neighborhoods Study (TNS) is a novel investigation of adverse social exposome and brain health leveraging 22 Alzheimer's Disease Research Centers (ADRCs). TNS aims to understand if the adverse social exposures increase Alzheimer's disease and related dementias (ADRD) risk. METHODS: TNS uses innovative methods to determine lifetime addresses of living (n = ≈ 3116) and brain bank cohorts (n = ≈ 8637). Addresses are linked to time-concordant adverse social exposome using the Area Deprivation Index (ADI) and summarized over time. Brain health measures are provided by the National Alzheimer's Coordinating Center. RESULTS: We highlight a general overview and methodology …
The Reporting And Methodological Recommendations For Observational Studies Estimating The Effects Of Deprescribing Medications (Remrose-D) Ispe-Endorsed Guidance, Kaleen N. Hayes, Joshua D. Niznik, Danijela Gnjidic, Frank Moriarty, Dimitri Bennett, Marie Laure Laroche, Denis Talbot, Matthew Alcusky, Maurizio Sessa, Antoinette B. Coe, Caroline Sirois, Andrew R. Zullo, Xiaojuan Li, Sri Harsha Chalasani, Jehath Syed, Mouna Sawan, Daniela C. Moga
The Reporting And Methodological Recommendations For Observational Studies Estimating The Effects Of Deprescribing Medications (Remrose-D) Ispe-Endorsed Guidance, Kaleen N. Hayes, Joshua D. Niznik, Danijela Gnjidic, Frank Moriarty, Dimitri Bennett, Marie Laure Laroche, Denis Talbot, Matthew Alcusky, Maurizio Sessa, Antoinette B. Coe, Caroline Sirois, Andrew R. Zullo, Xiaojuan Li, Sri Harsha Chalasani, Jehath Syed, Mouna Sawan, Daniela C. Moga
Epidemiology and Environmental Health Faculty Publications
Purpose: Pharmacoepidemiologic studies on deprescribing are challenging to implement, yet little guidance exists on methods to avoid bias and minimum reporting for replicability and appraisal. We developed consensus recommendations for the methods and reporting of observational studies that aim to examine the effects of deprescribing. Methods: We formed candidate recommendations based on our prior systematic review that methodologically appraised observational studies on deprescribing. We then conducted a two-round modified Delphi process with researchers working in deprescribing pharmacoepidemiology to refine, select, and reach consensus on recommendations for a checklist based on > 70% agreement of their importance. We termed this list the …
Effect Of Maternal Moringa Oleifera Leaf Supplementation On Maternal And Infant Nutritional Status And Human Milk Output, Suzanna L. Attia, Patrick M. Owuor, Silvia A. Odhiambo, Jerusha N. Mogaka, Raphael Ondondo, Irma Castro Navarro, Aric Schadler, Kristen Mcquerry, George J. Fuchs, Janet E. Williams, Katlyn N. Scarrow, Mark A. Mcguire, Michelle K. Mcguire, Carrie Waterman
Effect Of Maternal Moringa Oleifera Leaf Supplementation On Maternal And Infant Nutritional Status And Human Milk Output, Suzanna L. Attia, Patrick M. Owuor, Silvia A. Odhiambo, Jerusha N. Mogaka, Raphael Ondondo, Irma Castro Navarro, Aric Schadler, Kristen Mcquerry, George J. Fuchs, Janet E. Williams, Katlyn N. Scarrow, Mark A. Mcguire, Michelle K. Mcguire, Carrie Waterman
Biostatistics Faculty Publications
Background: Feeding of human milk enhances infant health and survival over alternative feeding methods, but early cessation often occurs due to perceived or real insufficient milk supply. Moringa oleifera leaves are nutrient dense and may increase milk output. Objectives: We investigated the impact of maternal dried moringa leaf powder supplementation (moringa) on milk composition and output and infant and maternal health. Methods: Breastfeeding mother–infant pairs (n = 50) living in Kisumu County, Kenya, were cluster-randomized by location to consume moringa powder (20 g/d) in corn porridge (the moringa group) or corn porridge alone (the control group) for 3 mo. Milk …
Knockout Of Perilipin-2 In Microglia Alters Lipid Droplet Accumulation And Response To Alzheimer’S Disease Stimuli, Isaiah O. Stephens, Lance A. Johnson
Knockout Of Perilipin-2 In Microglia Alters Lipid Droplet Accumulation And Response To Alzheimer’S Disease Stimuli, Isaiah O. Stephens, Lance A. Johnson
Physiology Faculty Publications
Highlights: What are the main findings? Knockout of Plin2 in microglia reduces lipid droplet burden, while enhancing phagocytic clearance capacity. Transcriptomic, bioenergetic, and lipidomic analyses reveal that loss of Plin2 reprograms microglial metabolism toward reduced TAG storage and improved mitochondrial resilience. What are the implications of the main findings? Plin2 serves as a key regulator of microglial lipid droplet stability, metabolic flexibility, and immune function under Alzheimer’s-relevant stressors. Targeting Plin2 may represent a therapeutic strategy to alleviate lipid droplet-driven dysfunction and restore microglial performance in aging and neurodegeneration. Lipid droplets (LDs) are emerging as key regulators of metabolism and inflammation, …
Mechanisms Matter, Nicole L. Collins, Kenneth S. Campbell
Mechanisms Matter, Nicole L. Collins, Kenneth S. Campbell
Physiology Faculty Publications
No abstract provided.
When Performance Takes Priority, Matthew D. Whitwer, Joseph H. Hammer, Brenna Gomer, Elahe Vahidi, Sarah A. Wilson
When Performance Takes Priority, Matthew D. Whitwer, Joseph H. Hammer, Brenna Gomer, Elahe Vahidi, Sarah A. Wilson
Educational, School, and Counseling Psychology Faculty Publications
Engineering education is at a critical juncture where supporting student mental health is essential for fostering persistence, equity, and the development of a resilient and innovative workforce. Yet, undergraduate engineering students experiencing mental health concerns are often unlikely to seek professional help. To identify factors that account for this gap in treatment, this project administered the Undergraduate Engineering Mental Health Help Seeking Instrument to 1903 engineering undergraduates across five institutions. Correlations and regression were used to examine the links between help-seeking intention and (a) help-seeking mechanisms (e.g., attitude, perceived norm, self-efficacy) and (b) beliefs about seeking help. Students’ personal evaluation …
Preferences For Clinical Trial Participation Among People Who Use Drugs In Rural Oregon And Appalachian Ohio, Kathryn E. Lancaster, Caroline W. Koudelka, Miriam R. Elman, Madison N. Enderle, Sarann Bielavitz, Angela T. Estadt, Ryan R. Cook, P. Todd Korthuis, April M. Young
Preferences For Clinical Trial Participation Among People Who Use Drugs In Rural Oregon And Appalachian Ohio, Kathryn E. Lancaster, Caroline W. Koudelka, Miriam R. Elman, Madison N. Enderle, Sarann Bielavitz, Angela T. Estadt, Ryan R. Cook, P. Todd Korthuis, April M. Young
Epidemiology and Environmental Health Faculty Publications
Background: Rural communities in the United States face significant challenges in participating in clinical trials, despite being heavily impacted by opioid and injection drug use epidemics. Barriers such as transportation, stigma, and limited resources often deter rural people who use drugs (PWUD) from engaging in research. Discrete choice experiments (DCEs) can help identify trial design features that support participation by eliciting participant preferences. Methods: We selected DCE attributes and attribute levels through literature review and qualitative interviews. Peer-based Retention of People who Use Drugs in Rural Research (PROUD-R2) study participants in rural Oregon and Appalachian Ohio completed the …
Comparison Of Alcohol-Induced Hepatoprotective Effects Of The High Fischer Ratio Oligopeptides With/Without Half Substitution By Pueraria Lobata, Yongke Deng, Qin Zhao, Na Chen, Zhiqin Zhang, Jingxuan Wang, Hongbing Fan, Haimei Liu, Lili Zhang
Comparison Of Alcohol-Induced Hepatoprotective Effects Of The High Fischer Ratio Oligopeptides With/Without Half Substitution By Pueraria Lobata, Yongke Deng, Qin Zhao, Na Chen, Zhiqin Zhang, Jingxuan Wang, Hongbing Fan, Haimei Liu, Lili Zhang
Animal and Food Sciences Faculty Publications
Long-term excessive intake of alcohol can cause serious damage to the liver, and the study of natural active ingredients with hepatoprotective effects is of great significance for the prevention and treatment of alcoholic liver injury. This study explored the ameliorative effects of high F-value oligopeptides (HFOPs) from Chlamys farreri, Pueraria lobata extract (PL), and their complex (HFOPs + PL) on alcoholic liver injury. Results showed HFOPs + PL significantly reduced alanine aminotransferase (ALT) and aspartate aminotransferase (AST) leakage, increased superoxide dismutase (SOD) and glutathione (GSH) activities, and decreased the production of malondialdehyde (MDA) and inflammatory factors in alcohol-induced HepG2 cells. …
Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao
Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao
Animal and Food Sciences Faculty Publications
The gonad is one of the major byproducts of sea cucumber. Four novel antioxidant peptides (NPWGQ, PGHPF, VPYPR and ATGPQGPAGQRGPAGPTGPTGPAG) were isolated and identified from sea cucumber gonad proteins through enzymatic hydrolysis and antioxidant activity-guided fractionation, bioinformatics approaches and in silico screening. These peptides demonstrated great free radical (2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS))-scavenging activity and notable superoxide dismutase (SOD)-activation capacity. Molecular docking and molecular dynamics simulation data suggested that these peptides could form strong binding with SOD through hydrogen bonding, electrostatic interactions, and hydrophobic interactions. Among these peptides, NPWGQ displayed the most potent antioxidant and SOD-activating effects. Through searching …
The Performance, Energy And Nutrient Utilization, And Bone Mineralization Of Broiler Chickens Fed Corn-Soybean Meal-Based Diets With Reduced Metabolizable Energy, Calcium, And Available Phosphorus Supplemented With Exogenous Enzymes, Megan M. Bauer, Tuoying Ao, Jacqueline P. Jacob, Michael J. Ford, Anthony J. Pescatore, Ronan F. Power, Sunday A. Adedokun
The Performance, Energy And Nutrient Utilization, And Bone Mineralization Of Broiler Chickens Fed Corn-Soybean Meal-Based Diets With Reduced Metabolizable Energy, Calcium, And Available Phosphorus Supplemented With Exogenous Enzymes, Megan M. Bauer, Tuoying Ao, Jacqueline P. Jacob, Michael J. Ford, Anthony J. Pescatore, Ronan F. Power, Sunday A. Adedokun
Animal and Food Sciences Faculty Publications
This study evaluated the performance and energy and nutrient utilization of broiler chickens fed corn-soybean meal-based diets supplemented with a naturally fermented enzyme complex containing xylanase and phytase. This was evaluated using 300 one-day-old male Cobb broiler chicks in a randomized complete block design with five dietary treatments replicated 10 times with 6 chicks per replicate. The treatments consisted of a positive control (PC) group containing commercially recommended energy and nutrient levels, a negative control (NC) group with reduced metabolizable energy, calcium, and available phosphorus, and three levels of exogenous enzyme supplementation to the NC diet at 150, 200, 250 …
A Second Chance At The Second Amendment, Blake Creekmur
A Second Chance At The Second Amendment, Blake Creekmur
Kentucky Law Journal
No abstract provided.
The Wnba's 2020 Collective Bargaining Agreement: A Slam Dunk For Working Women And Mothers, Josh Lens
The Wnba's 2020 Collective Bargaining Agreement: A Slam Dunk For Working Women And Mothers, Josh Lens
Kentucky Law Journal
No abstract provided.
Faux Federalism, Amanda B. Hurst
Protecting Unbelief: Restoring Section Five Of Kentucky's Constitution, Samuel Weaver
Protecting Unbelief: Restoring Section Five Of Kentucky's Constitution, Samuel Weaver
Kentucky Law Journal
No abstract provided.
Trauma, Coercion, And The Tools Of Trafficking Exploitation: Examining The Consequences For Children And Youth In The Justice System, Sarah Bendtsen Diedhiou, Sarah Roberts, Christine Raino
Trauma, Coercion, And The Tools Of Trafficking Exploitation: Examining The Consequences For Children And Youth In The Justice System, Sarah Bendtsen Diedhiou, Sarah Roberts, Christine Raino
Kentucky Law Journal
No abstract provided.
A Legal Examination Of The Experiences Of Two Domestic Sex Trafficking Survivors In America, Azurdee Garland, Maira Gomez
A Legal Examination Of The Experiences Of Two Domestic Sex Trafficking Survivors In America, Azurdee Garland, Maira Gomez
Kentucky Law Journal
No abstract provided.
Drug-Based Coercion And Sex Trafficking: Bridging The Legal Disconnect, Vanessa Bouché, Madeleine Bailey
Drug-Based Coercion And Sex Trafficking: Bridging The Legal Disconnect, Vanessa Bouché, Madeleine Bailey
Kentucky Law Journal
No abstract provided.
Crises Collide: Examining The Intersection Of Sex Trafficking And Opioid Use, Jennifer L. Brinkley
Crises Collide: Examining The Intersection Of Sex Trafficking And Opioid Use, Jennifer L. Brinkley
Kentucky Law Journal
No abstract provided.
Flesh Markets: Sex Trafficking, Opioids, And The Legal Process To Eradicate The Demand, Blanche Bong Cook
Flesh Markets: Sex Trafficking, Opioids, And The Legal Process To Eradicate The Demand, Blanche Bong Cook
Kentucky Law Journal
No abstract provided.
Cruel And Unusual Camping, Cameron Baskett