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I Need To See Me On Tv: Parasocial Affirmations Of Sexual And Gender Identity Development Of Lgbtq+ Mass Media Consumers, Donald I. Lowe

Theses and Dissertations--Communication

This dissertation presents a new cycle model of media usage by LGBTQ+ community members in the United States that reveals a purpose previously unnamed and undefined. While parasocial contact, parasocial interaction, and parasocial relationships have been present in the academic literature for quite some time (as early as 1956 when Horton and Wohl first wrote of the phenomenon), use of media to parasocially affirm one’s LGBTQ+ status is unique to this study. This study used qualitative methods to examine a specific mass media audience, LGBTQ+ individuals, and asked them, in one-on-one interviews, how they utilize mass media to assist with …

The Consent Of Man: An Examination Of Privacy Awareness, Surveillance, And Privacy Policy (Mis)Use, Will Reilley Silberman

Theses and Dissertations--Communication

The problem of privacy is nuanced, pervasive, and requires an elevated approach. Given the lack of consistency with regard to privacy’s conceptualization and operationalization, research is needed that examines variables related to privacy to better understand how privacy operates in the present day. This dissertation aims to better understand nuances of privacy by gauging knowledge of online privacy, technological affordances related to privacy, and knowledge of surveillance. In this study, human subjects from a large southern University were presented with an opportunity to use a privacy-invasive smartphone application. After doing so, they viewed one of three privacy policies. Finally, they …

Communication Strategies To Intervene In Intimate Partner Violence Among Young Adult Couples, Kaylee Marie Lukacena

Theses and Dissertations--Communication

Intimate partner violence (IPV) is a social and behavioral health issue of importance among the young adult population (Cupp et al., 2015). IPV includes acts of physical violence, sexual violence, psychological aggression, and stalking enacted by an intimate partner (Smith, Zhang, Basile, Merrick, Wang, Kresnow, & Chen, 2018). In the United States., approximately one in three women and one in ten men experience IPV during their lifetime (Smith et al., 2018). Furthermore, over more than 70% of women who experience indicate that the first act occurred before the age of 25. One approach to preemptively address IPV on college campuses …

An Examination Of Communication Sequencing In Enacted Support Interactions For People With Major Depressive Disorder, Madison Adams

Theses and Dissertations--Communication

Social support is integral to helping one manage Major Depressive Disorder [MDD], but enacted social support, or the supportive behavior itself, is not always beneficial. Using a normative theoretical perspective on social support and theory related to sequencing as guiding frameworks, in this thesis I examined common sequential patterns of enacted support between support providers and individuals with MDD. Moreover, I investigated how individuals with MDD evaluated the helpfulness of each of the different sequential patterns. To examine the sequential patterns and how individuals with MDD evaluated their helpfulness, I interviewed 20 participants who had been diagnosed with MDD. The …

Does Bullying Victimization In Middle Childhood Influence Adolescent Risk Behaviors: Differences Across Racial/Ethnic Groups?, Shawndaya Sabrina Thrasher

Theses and Dissertations--Social Work

Bullying is a public health problem that negatively affects millions of children annually and can have serious, long-lasting effects on victims. Emergent research concludes a higher prevalence of bullying occurs in earlier school years, especially among racial/ethnic minorities. Evidence also suggests that risk behaviors associated with bully victimization may vary by racial/ethnic profile, leading to disproportionate chances of adverse psychosocial and health-related behaviors. Therefore, racial/ethnic minority youth may be more likely to cope with being bullied through risk behaviors (e.g., coping by fighting).

Current investigations of racial/ethnic differences in the bullied-risk relationship examine few risk behaviors (i.e., academic performance and …

A Brief Review Of Fda’S Novel Tools For Ensuring Pharmaceutical Quality In The Human Drug Supply Chain, Heather R. Campbell, Robert A. Lodder

Pharmaceutical Sciences Faculty Publications

Purpose

Pharmaceutical manufacturers execute quality control operations and Good Manufacturing Practices (GMP) to provide safe drugs. The Federal Drug and Food Administration (FDA) is tasked with ensuring manufacturers are performing such procedures. Faced with limited resources the FDA has developed novel tools to aid pharmaceutical manufacturing oversight. This paper briefly reviews these tools.

Methods

Current inspection approaches employed by the FDA are identified by searching the FDA’s guidances, the Code of Federal Regulations, public reports and other online resources.

Outcomes

Industry

A risk-based site selection model (SSM) is used to prioritize on-site inspections for FDA investigators. Theoretically, the SSM allows …

Zilpaterol And Ractopamine: Reaching Consensus On Trace-Level Transfers To Racehorses, Jacob Machin, Kimberly Brewer, Clara K. Fenger, Sarah White-Springer, Abelardo Morales-Briceno, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

In this article, we review the investigation of trace amounts of b-2 adrenergic agonists, a drug class that possess significant risk to the integrity of horse racing whether intentionally used or through the inadvertent contamination of feed.

Arabinoxylan Structural Profiling Of Cool-Season Pasture Grasses Via High-Performance Anion-Exchange Chromatography With Pulsed Amperometric Detection (Hpaec-Pad) Analysis Of Endoxylanase Digests, Glenna Erin Joyce

Theses and Dissertations--Animal and Food Sciences

Arabinoxylan (AX) is a major structural polysaccharide found in the cell walls of monocots such as cereal grains and pasture grasses. The variety of AX structural components and substitution patterns contribute to AX structural diversity between different monocot species as well as plant tissues.

The rumen is the first digestion site of masticated food material in cattle and provides 70% of energy to host through fermentation of forage. There are many species of pasture grasses that act as a forage source. Differences in AX structure found in these pasture grasses may impact rumen microbial fermentation. Understanding the AX structure of …

Predicting Tomorrow: Optimizing The Early Detection Of Disease And Disease Recovery In Dairy Calves Using Precision Technologies, Melissa Cantor

Theses and Dissertations--Animal and Food Sciences

The leading causes of morbidity and mortality in preweaned dairy calves are diarrhea and bovine respiratory disease complex (BRD). The delayed detection of these diseases in calves can also delay intervention and disease recovery. The overarching objective of this dissertation was to follow a cohort of calves daily for the first 90 days of life for naturally occurring clinical BRD bouts and diarrheal bouts. The objective answered if feeding behaviors and activity levels were different in at-risk calves during BRD development and BRD recovery from an antimicrobial intervention. Furthermore, the potential of colostrum replacer as a feeding intervention strategy to …

Influence Of Dietary Manipulation On The Relationship Between Temperament Measures And Growth In Beef Cattle: Endophyte Exposure, Phytogenic Supplementation, And Controlled Feeding, Paul Shanks

Theses and Dissertations--Animal and Food Sciences

The influence of dietary factors (including endophyte exposure, phytogenic supplementation, and controlled feeding) on relationships between exit velocity (EV), growth performance in grazing and finishing cattle, and carcass characteristics were explored. Two grazing studies were conducted evaluating EV effects on cattle grazing both toxic and nontoxic endophyte-infected tall fescue. Cattle were followed through two subsequent finishing studies and an additional beef cattle finishing beef cattle study was also conducted. Results from these studies agree with many literature reports indicating that EV measures relate to growth performance and associated carcass traits in beef cattle being fed high energy diets in confinement, …

Impact Of Mineral Supplementation On Intake Behavior And Blood Flow In Growing Beef Cattle Exposed To Fescue-Derived Alkaloids, Hannah Marie Herzing

Theses and Dissertations--Animal and Food Sciences

Consumption of endophyte-infected tall fescue by cattle has repeatedly been shown to negatively impact dry matter intake (DMI), growth rate, and circulating prolactin concentrations. The objective of the current study was to determine if a mineral supplementation would mitigate the negative effects of fescue-derived alkaloid consumption on feed intake, circulating prolactin, and the vascular system. Twelve Angus crossbred steers were used in a triplicated Latin square design consisting of three 28 d experimental periods. Treatments consisted of three top-dressed mineral supplements (142 g/head/d): a non-medicated control (CON), commercially available Fescue EMT® Mineral Defense (EMT), and a test prototype (EMT 2). …

Monocyte Abundance And White Blood Cell Expression Of Prolactin And Nf-Kb Pathway Genes In Beef Steers Are Altered By Grazing Toxic Endophyte-Infected Tall Fescue And Lipopolysaccharide Challenge, Cecilia Winfrey

Theses and Dissertations--Animal and Food Sciences

Experiment 1 tested the hypothesis that ad libitum consumption of a 1:1 blend (MIX) of sodium selenite (ISe) and SELPLEX vs solely ISe as selenium (Se) supplements (27 ppm) in a vitamin-mineral mix (V-M) by steers subjected to summer-long grazing of toxic endophyte-infected tall fescue (TE) would ameliorate the negative effects of TE by positively affecting the expression pattern of prolactin (PRL) and NF-kB pathway genes by circulating leukocytes (WBC). Experiment 2 tested the hypothesis that the MIX form of supplemental Se also would ameliorate the negative effects of in vitro blood lipopolysaccharide challenge (LPS) on WBC gene expression. The …

Impact Of Feeding Foods Containing Industrial Hemp-Derived Cannabidiol On Canine Health And Well-Being, Elizabeth M. Morris

Theses and Dissertations--Animal and Food Sciences

Anecdotal evidence of beneficial behavioral and health effects of cannabidiol (CBD) use in companion animals has amplified the need to elucidate safety and potential impacts of CBD use. The purpose of this investigation was to determine the impact of industrial hemp-derived CBD administration on canine health and well-being. We hypothesized that CBD would produce beneficial effects on canine behavior without negatively impacting animal health. Dog treats were formulated to include CBD and shown to be palatable across a range of CBD inclusion levels. Dogs were supplemented with CBD treats and subjected to a noise-induced fear response test to assess potential …

Assessing The Impact Of Teacher Self-Efficacy On Teacher Led Physical Activity, Donovan Willard-Lee Ross

Theses and Dissertations--Education Sciences

Many children are not meeting national physical activity recommendations and are sedentary during the school day. This has led teachers to implement classroom physical activity to increase movement of their students. This dissertation focused on student perceptions of classroom physical activity and teacher self-efficacy to implement it. This dissertation includes three studies focusing on classroom physical activity: (1) student perceptions of classroom physical activity, (2) an examination of the relationship between teacher self-efficacy and implementation of classroom physical activity, and (3) a description of factors related to teacher implementation of classroom physical activity, including methods of implementation and teacher confidence. …

Death, Discipline, And The Dead: Biopolitical Rhetoric In Early Modern English Texts, Leslie Raybuck Malland

Theses and Dissertations--English

Death, Discipline, and the Dead: Biopolitical Rhetoric in Early Modern English Texts locates allusions to the biopolitical culture of Early Modern England within popular English texts. Through my examination of the period’s fascination with death—public executions, newly-authorized anatomies—and the ways in which death, as well as the treatment of the dead, was authorized by and supported the ideological aims of the state, my research identifies how those themes carry over into the most popular works of the day, reviewing instances of both verbal and nonverbal rhetoric across genres to find allusions to biopower — or, state control of the biological. …

Collaborative Competition In Homeless Services: Three Essays On Federal-Local Partnerships, Andrew Alfred Sullivan

Theses and Dissertations--Public Policy and Administration

The United States’ federal government funds homeless services provided at the local level through the McKinney-Vento Act, encouraging collaboration among providers. This dissertation studies three aspects of homelessness: merging of local planning bodies, identification of homeless students, and the relationship between experiencing homelessness in high school and long-term educational outcomes.

The first chapter studies the effect of merging Continuums of Care (CoCs), local planning bodies for homeless services. While merging brings organizations into the same network and could make use of economies of scale, it brings service provision to a less-local level, taking away responsiveness to the community and inter-jurisdictional …

Two Essays On Governments Devolving Fiscal Authority To Lower-Level Actors, Jinsol Park

Theses and Dissertations--Public Policy and Administration

Over the past decades, there have been efforts across the globe to break the grip of the centralized power of government and devolve authority to lower-level actors. The devolution of authority in the governance system can take place in various ways: the central government can devolve authority, responsibility, and functions to local governments; or a local government can delegate its authority to make policy decisions to the citizenry, for example, as a form of public participation. In a broad sense, we can group all these government activities to devolve power to lower-level actors and call it “decentralization.” This dissertation attempts …

Rehabilitation Counseling Perceptions And Psychosocial Stressors Of Arab-Immigrant Caregivers Of Children With Autism Spectrum Disorder, Maram Alfulayyih

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

This research study provides important insights on the psychosocial stressors faced by U.S. Arab immigrants when raising a child with ASD, their perceptions of rehabilitation counseling, and the implications of rehabilitation counseling practice based on gender, age, education, and race. More specifically, this study has provided a detailed literature review as well as new insights into the challenges faced by the caregivers and recommendations that rehabilitation counselors should consider when helping these families overcome psychosocial issues and adjust to their circumstances. Using the DASS-21 questionnaire and a multi-factor analysis, it has identified specific groups of caregivers that may need help …

Mobile Technology Use During The Covid-19 Pandemic, Yi Lin

Theses and Dissertations--Gerontology

The COVID-19 pandemic led to quarantines and mandatory spatial distancing; people of all ages were encouraged to use technologies instead of actual human contact for COVID-19 prevention and daily activities. The special circumstances of living plus innovation and promotion of mobile applications (apps) during the pandemic influenced mobile technology use behavior. In this study we explored age differences in mobile technology use, the factors that influenced use behavior during the COVID-19 pandemic, and proposed a research model that aimed to predict behavioral intention and mobile technology use behavior. A pilot-tested survey was distributed through online survey software. Participants were 35 …

Electrifying: Facilitating The Transition To Electric Lawn And Garden Equipment, Bryan Hull, Ryan Murphy

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Development And Clinical Validation Of Knowledge-Based Planning Models For Stereotactic Body Radiotherapy Of Early-Stage Non-Small-Cell Lung Cancer Patients, Justin David Visak

Theses and Dissertations--Radiation Medicine

Lung stereotactic body radiotherapy (SBRT) is a viable alternative to surgical intervention for the treatment of early-stage non-small-cell lung cancer (NSCLC) patients. This therapy achieves strong local control rates by delivering ultra-high, conformal radioablative doses in typically one to five fractions. Historically, lung SBRT plans are manually generated using 3D conformal radiation therapy, dynamic conformal arcs (DCA), intensity-modulated radiation therapy, and more recently via volumetric modulated arc therapy (VMAT) on a C-arm linear accelerator (linac). Manually planned VMAT is an advanced technique to deliver high-quality lung SBRT due to its dosimetric capabilities and utilization of flattening-filter free beams to improve …

Two Essays On Food Environment, Nutrition, And Food Insecurity, Suliman Abdulaziz Almojel

Theses and Dissertations--Agricultural Economics

A healthy food environment is fundamental to good health. It contributes to the reduction of obesity and the development of healthy eating habits. In spite of this, many people in the United States (US) have been hypnotized to become obese due to the current food environment. Recently, the US has consistently ranked high in the world in terms of obesity. The rising rate is symptomatic of consuming unhealthy diets. Besides, the double-edged crisis of the US food environment and obesity poses a major threat to food security and public health. Therefore, studying the US food environment is important to sustain …

Exploring The Relationships Between Cultural Values And Diet Patterns Among Mexican And Cuban Immigrants In Kentucky, Nasreen Omran

Theses and Dissertations--Nutrition and Food Systems

The number of Latinx in the U.S. is expected to grow to about 28 percent of the population by the year 2060. As the number of Latinx increases in the U.S. it is important to understand how cultural beliefs influence dietary behaviors as Latinx are disproportionately affected by diet related disease such as diabetes mellitus, cancer, and cardiovascular disease. The aim of this secondary data analysis is to examine the relationship between family values, gender roles, and religious values on diet patterns in adult Mexican and Cuban immigrants in Kentucky utilizing the Mexican American Cultural Values Scale. The study findings …

Design And Analyses Of School-Based Violence Prevention Cluster Randomized Trials, Md. Tofial Azam

Theses and Dissertations--Epidemiology and Biostatistics

Interpersonal violence such as teen dating violence is a severe public health problem. Teen dating violence, including sexual violence (unwanted sexual contacts or activities), physical and psychological dating violence, sexual harassment, and stalking, affects high school students' physical and mental health and academic achievement in the United States. Dating violence is linked to psychological abuse perpetration in the future, depression, anxiety, and hostility. The teen dating violence victimization experience was related to antisocial behavior, drug abuse, increased heavy drinking, depression, suicidal ideation, smoking, and adult interpersonal violence victimization during adolescence. The detrimental effects of interpersonal violence demonstrate the critical importance …

A Novel Role For Neurotensin In Regulation Of Stem Cell Function In The Small Intestine, Stephanie Rock

Theses and Dissertations--Toxicology and Cancer Biology

Neurotensin (NT) is a nutrient-regulated gut hormone that plays important roles in lipid absorption, obesity, metabolic disorders, and normal and neoplastic growth in the intestine. In this study, we 1) elucidate the mechanisms regulating NT release from endocrine cells, 2) examine the role of NT on proliferation and stem cell function in the small intestine and 3) define the effects of NT on colorectal cancer stem cells. We report that NT release from endocrine cells is enhanced by the MAPK scaffold protein Kinase Suppressor of Ras 1 (KSR1) and the exocyst complex component 70 (Exo70). Moreover, free fatty acid stimulated …

Micromending The Metabolic Rift: An Analysis Of Food Waste Composting Systems In Lexington, Kentucky, Casey Byrd

Theses and Dissertations--Geography

The metabolic rift theory explores materials and social exchanges between rural and city communities and human-nature relations. Metabolic rifts can exist both environmentally and socially and are often geographically or culturally unique. Ultimately the metabolic rift is earmarked by increasing disconnection between humans and their environment. This thesis draws upon life cycle analysis studies, social-economic studies, and environmental and sustainability studies to argue that large-scale contemporary urban composting efforts, although well intended, are insufficient to mitigate the effects of the metabolic rift. Mobilizing theories around capitalism and the metabolic rift, this research paper connects social, environmental, and economic notions of …

Bio-Spatial Policing In Theory And Practice: Examining Impacts And Resistance Through Mobilities And Children's Everyday Life, Emily Kaufman

Theses and Dissertations--Geography

Despite decades of reforms and technological innovations, increasing evidence shows that state securitization disproportionately harms already racially, spatially, and socio-economically marginalized communities. My research investigates uneven impacts of state securitization, from punitive welfare programs to school surveillance to policing. Across sites, I focus on scales, voices and the everyday lived experiences often left out of scholarly discourse and sensational media. In the current climate of growing awareness and scholarship on police violence, my dissertation addresses three less-studied areas: 1) the interplay between racial, gendered, spatial, and technified police practices; 2) how these practices impact the everyday lives of those racially …

Effects Of Season And Nutrition On Insulinemic Responses In Insulin Dysregulated Horses, Erica Lyn Macon

Theses and Dissertations--Veterinary Science

Insulin dysregulation (ID) is the main risk factor for the development of hyperinsulinemia-associated laminitis (HAL). ID in the equid has been extensively researched; however, recommendations for diagnosing and managing ID horses have originated from work completed in other models, such as the ID pony and healthy horse. Therefore, our overall objective was to improve current diagnostic tools and nutritional management strategies by investigating the effect of season, the fed and fasted state on the oral sugar test (OST) and dietary nutrient content on insulinemic responses in the ID horse. To address this, four main objectives with three specific aims were …

Evaluating The Incidence Of Melanoma And Lung Cancer Of Current And Former Active-Duty U.S. Military Who Were Deployed In Support Of Operation Enduring Freedom And Operation Iraqi Freedom, Brian Kovacic

Theses and Dissertations--Epidemiology and Biostatistics

The incidence of melanoma and lung cancer has been gradually increasing in the United States over the past three decades with the reputed causes due to etiological and environmental exposures, and tobacco usage. There has been concern that melanoma and lung cancer incidence among military personnel may be associated with deployment to environments with intense sun exposure and increased smoking rates due to post-traumatic stress disorder. The aim of this study was to examine associations between deployment in support of Operation Enduring Freedom (OEF) or Operation Iraqi Freedom (OIF), from 2001 through 2015, with subsequent melanoma and lung cancer incidence. …

Sexual Behaviors Associated With Online Partner-Seeking Among Men Who Have Sex With Men From Small/Midsized Towns Or Rural Areas In Kentucky, Vira Pravosud

Theses and Dissertations--Epidemiology and Biostatistics

The HIV epidemic remains one of the most significant public health issues in the United States, particularly among men who have sex with men (MSM). New avenues for partner-seeking have emerged over the past three decades, including through the Internet, social media, and geosocial networking applications. Consisting of three cross-sectional studies, this dissertation research aimed to determine associations between the use of various online tools for partner-seeking (hereafter collectively referred to as “apps”) and HIV-related sexual behaviors among 252 young adult MSM residing in small/midsized towns or rural areas in Central Kentucky, a group that has been under-represented in the …