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Articles 3211 - 3240 of 18293
Full-Text Articles in Entire DC Network
Saint Louis, Missouri Maternal Mortality Prevention Program: Rose Program, Abbi Peck
Saint Louis, Missouri Maternal Mortality Prevention Program: Rose Program, Abbi Peck
Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)
In the United States, maternal mortality has become a growing public health concern after recent studies revealed significant disparities in maternal health outcomes when compared to other high-income countries (The Commonwealth Fund, 2020). The World Health Organization (WHO) defines maternal mortality as the death of a pregnant woman or the death of a woman within 42 days of delivery, miscarriage, termination, or ectopic pregnancy (Centers for Disease Control and Prevention, 2022a). From 2017-2019, the maternal mortality in Saint Louis, Missouri, the state’s largest and most populated metropolitan area, was determined to be 36.4 maternal deaths per 100,000 live births. This …
Physical Inactivity And Single-Female Caregivers, Johanna Hoch, Rachel Hogg-Graham Dr., John Lyons Dr., Maureen Jones Dr.
Physical Inactivity And Single-Female Caregivers, Johanna Hoch, Rachel Hogg-Graham Dr., John Lyons Dr., Maureen Jones Dr.
Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)
Physical activity is vital for human health. However, many adults in the United States and beyond do not reach the pre-determined recommended levels of activity needed for health benefits. Single-female caregivers present a unique and vulnerable population that is often more inactive than their partnered peers or single-male caregivers. The primary purpose of this cross-sectional investigation was to identify the prevalence of physical inactivity in single-family, female-led households and determine differences in personal factors and social determinants of health between single-female caregivers who indicated they were physically active compared to single-female caregivers who indicated they were not physically active. A …
Implementation Of A School-Based Adolescent Pregnancy Prevention Program In Harlan County, Kentucky, Jaycea Frederick
Implementation Of A School-Based Adolescent Pregnancy Prevention Program In Harlan County, Kentucky, Jaycea Frederick
Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)
Kentucky has the 6th highest rate of adolescent pregnancy in the United States and Harlan County ranks among the highest rates in the state. Adolescent pregnancy is a public health problem and costs taxpayers in the United States around $9.4 billion each year. Overall, there have been declines in adolescent pregnancy but the national average soars above those in other Western industrialized nations such as the United Kingdom. Implementing a comprehensive sexual health education program in a public school setting is an efficient strategy to reach numerous adolescents and influence sexual health knowledge and help to delay the initiation …
Impact Of A Parent Education Program On Parents Of Children With Complex Congenital Heart Disease Prior To Discharge Home, Laura Elkhoury
Impact Of A Parent Education Program On Parents Of Children With Complex Congenital Heart Disease Prior To Discharge Home, Laura Elkhoury
DNP Projects
Abstract
Background and Purpose: Children with complex medical needs, such as children with complex congenital heart disease, are at risk for hospital readmission, morbidity, and mortality related to disease complications. Parents must be adequately prepared to care for their children following hospital discharge to prevent hospital readmission and complications. This study seeks to evaluate the impact of an education intervention on parental knowledge and stress related to caring for their child with complex medical needs.
Methods: The study design is a quasi-experimental, nonequivalent control pre-test/post-test design. The pre-test was administered prior to the educational intervention, with the post-test …
Broken Down: A Mixed Methods Inquiry Examining The Mechanics Of The Segmenting Principle Using Flipped Math Instruction For Automotive Technicians, John David Baumgarten
Broken Down: A Mixed Methods Inquiry Examining The Mechanics Of The Segmenting Principle Using Flipped Math Instruction For Automotive Technicians, John David Baumgarten
Theses and Dissertations--Curriculum and Instruction
Mayer’s Segmenting Principle requires an instructional designer to both break the instruction into small functional pieces and pause instruction between each of these pieces until a student signals readiness to move on. Over decades of research, investigators have consistently demonstrated that segmented multimedia content achieves better learning assessment outcomes than continuous content across various academic disciplines, ages, and ability levels. While current segmenting research has shown impressive results in tightly controlled experimental scenarios, there is far less research on its application in the real world. To date, the vast majority of segmenting principle studies only assess short-term knowledge using an …
Addressing A Cohort Discrepancy Among Ninth-Grade Students At A Rural/Suburban High School, Bryley Keaton Murphy
Addressing A Cohort Discrepancy Among Ninth-Grade Students At A Rural/Suburban High School, Bryley Keaton Murphy
Theses and Dissertations--Educational Leadership Studies
Ninth grade is a critical period where some children experience academic and social growth, while others struggle to navigate their new context, leading to reduced outcomes at school and worsened physical/mental health (Benner & Graham, 2007; Rice, 2001). This mixed-methods action research (MMAR) study addressed how professional practice changes could better support students during this foundational period. Quantitative data was collected from school databases to compare the rate of student success and identify demographic discrepancies, while qualitative data was used to identify possible causes. These data were then integrated to create insightful meta-inferences into the problem of practice. From these …
Understanding First-Year Undergraduate Students Safety, Savviness, And Social Etiquette Online, Collis Ray Robinson
Understanding First-Year Undergraduate Students Safety, Savviness, And Social Etiquette Online, Collis Ray Robinson
Theses and Dissertations--Educational Leadership Studies
Student’s engagement and interaction online continue to grow as technological advancements increase. The ability to engage and connect is endless today compared to two decades ago. This mixed methods action research study examines the digital citizenship knowledge of first-year students at a private liberal arts work college. The study focuses on student’s understanding of digital citizenship through the lens of safety, savviness, and social engagement online. Additionally, the study seeks to explore students, staff, and faculty perceptions around more education about digital citizenship at the undergraduate level. This study discusses the problem of practice, methodological framework, and study plan in …
Principals As Instructional Leaders: Building Knowledge Of Applied Learning To Confidently Lead Implementation, Janell Lynn Mcclure
Principals As Instructional Leaders: Building Knowledge Of Applied Learning To Confidently Lead Implementation, Janell Lynn Mcclure
Theses and Dissertations--Educational Leadership Studies
Principals need to understand best practices and research-based strategies that foster student success and that align to their instructional expectations and professional goals. Some of those practices include applied learning strategies such as integrated learning, student-driven learning, and authentic applications. Unfortunately, little professional learning, specifically for principals, is made available on the topic of instructional leadership, current strategies, or applied learning in general. As a result, school leaders continue to follow a traditional instructional model that includes teacher-directed instruction, student recall of information, and standardized tests as measures of content mastery.
This dissertation was a mixed-methods action research study. The …
Cardiorespiratory And Muscle Recruitment Responses To Incremental Exercise In Flywheel-Based Inertial Training (Fit) Squats, Clara Joyce Mitchinson
Cardiorespiratory And Muscle Recruitment Responses To Incremental Exercise In Flywheel-Based Inertial Training (Fit) Squats, Clara Joyce Mitchinson
Theses and Dissertations--Kinesiology and Health Promotion
BACKGROUND: Spaceflight induces rapid loss of aerobic capacity and muscle strength. Flywheel-based Inertial Training (FIT) – a gravity-independent form of exercise previously used as a countermeasure against unloading-induced muscle atrophy – provides external resistance through moment of inertia (MOI) of a rotating disk in a velocity-dependent manner. Optimizing FIT for cardiorespiratory fitness may improve exercise efficiency and reduce hardware needs associated with deep space exploration. This modality of exercise has also been of interest among athletes of various disciplines due to its purported benefits on athletic performance. PURPOSE: To determine the cardiorespiratory and muscular recruitment responses to FIT with varying …
Intra- And Inter-Rater Reliability Of Maximum Torque Applied During Passive Elbow Range Of Motion Testing Post-Casting Of Supracondylar And Lateral Condylar Fractures In Children, Joseph T. Armstrong
Intra- And Inter-Rater Reliability Of Maximum Torque Applied During Passive Elbow Range Of Motion Testing Post-Casting Of Supracondylar And Lateral Condylar Fractures In Children, Joseph T. Armstrong
Theses and Dissertations--Kinesiology and Health Promotion
Elbow fractures account for a significant number of pediatric orthopedic injuries. The most common of these are the supracondylar and lateral condylar humeral fractures. When surgical repair is necessary casting and pinning of the elbow can affect the elbow’s range of motion (ROM), so recovery is monitored. Practices for measuring recovery are not standardized so measures may not be consistent. A possible novel measure to help account for different clinicians participating in the same study is maximum torque applied during elbow end ROM testing. This study uses several comparisons of maximum torque applied by three different clinicians during end ROM …
Effects Of Constant Load Exercise On Oxygen Consumption And Knee Joint Mechanics In Young Adults, Mariana Victoria Jacobs
Effects Of Constant Load Exercise On Oxygen Consumption And Knee Joint Mechanics In Young Adults, Mariana Victoria Jacobs
Theses and Dissertations--Kinesiology and Health Promotion
The rate of obesity and its adverse health consequences have continued to rise in the past several decades. Aerobic constant load exercise is recommended to reduce excess body mass, however the effects of constant load exercise on oxygen consumption (VO2) and knee joint mechanics are inconsistent when varying weight-status strategies are employed. The purpose of this study was to assess the influence of different weight classification strategies on VO2 and knee joint mechanics during constant load exercise. Participants walked on an instrumented treadmill at a self-selected speed for 30-minutes while gait mechanics and VO2 measures were determined. Between-group differences were …
Responses To Exercise Anchored To Vigorous Intensity Heart Rates, Djadmann Gustave
Responses To Exercise Anchored To Vigorous Intensity Heart Rates, Djadmann Gustave
Theses and Dissertations--Kinesiology and Health Promotion
Exercise prescription to improve cardiorespiratory endurance (CE) is often based on percentages of the reserve or maximum heart rate (HRpeak) or oxygen consumption rate (V̇O2peak)that reflect vigorous intensities (77-95% HRpeak, 64-90% V̇O2peak). These intensities elicit a rating of perceived exertion [RPE] response between 14-17 on the 6-20 Borg Scale. It is recommended that exercise within these ranges be sustained for 20-60min per session. The purposes of this study were to: 1) Determine the metabolic (V̇O2) and perceptual (RPE) responses as well as the sustainability of exercise (time to exhaustion [T …
Examination Of Physiological And Perceptual Responses During Sustained, Isometric, Fatiguing, Handgrip Exercise Anchored To Ratings Of Perceived Exertion, Minyoung Kwak
Theses and Dissertations--Kinesiology and Health Promotion
The purposes of this study were to: 1) Examine the patterns of force responses relative to critical force (CF) during submaximal, fatiguing, isometric handgrip exercise anchored to different rating of perceived exertion (RPE) levels (RPE=3, 5, and 7); 2) assess the loss of force during the task and the level of performance fatigability after each RPE hold; 3) examine the time course of changes and patterns of neuromuscular [electromyography (EMG) amplitude (AMP), mean power frequency (MPF), mechanomyography (MMG) AMP and MPF, and neuromuscular efficiency (NME) (i.e. force/EMG AMP)] and muscle oxygen saturation (% SmO2) responses during each RPE …
Sociocultural Predictors Of White Veterans’ Attitudes Towards Va Mental Health Care, Elyssa Christine Berney
Sociocultural Predictors Of White Veterans’ Attitudes Towards Va Mental Health Care, Elyssa Christine Berney
Theses and Dissertations--Educational, School, and Counseling Psychology
U.S. Veterans are less likely to seek help than their civilian counterparts despite having higher levels of self-reported distress, in part due to comparatively poorer attitudes towards seeking mental health treatment. While some aspects of cultural socialization (e.g., gender role expectations, certain types of stigma) have been established to influence Veterans’ attitudes towards mental health treatment, other aspects of health care access (e.g., trust in health care institutions or individual providers) may benefit from increased focus. Additionally, one aspect of cultural socialization that is understudied in white Veterans is that of racial-cultural socialization (i.e., whiteness). Much of the research into …
Physical Activity Preference And Participation In Middle School Age Students In Kentucky, Fabian Correia
Physical Activity Preference And Participation In Middle School Age Students In Kentucky, Fabian Correia
Theses and Dissertations--Kinesiology and Health Promotion
Physical activity (PA) in youth is significant as it begins to lay the fountain for a healthier lifestyle as children age. The benefits of being regularly physically active are plentiful as it improves muscle strength, cardiovascular, fitness, and cognitive functions (Rodgers, 2008). However, oftentimes in physical education classes, the voice of the student tends to go unheard. The purpose of this study was to determine how the perception or preference to be physically active differs by age, gender, and/or ethnicity in a middle school setting. The goal of this study is to shed ligt on how building a more inclusive …
Effect Of Sleep Restriction On Quadriceps’ Strength And Voluntary Activation, Scott Sigrist
Effect Of Sleep Restriction On Quadriceps’ Strength And Voluntary Activation, Scott Sigrist
Theses and Dissertations--Kinesiology and Health Promotion
Background: As little as three nights of sleep restriction reduces muscle strength. More than one-third of Americans are chronically sleep restricted (< 7.0 hours/night) and are at risk of muscle weakness (dynapenia). Presently, the mechanistic cause of sleep restriction-induced dynapenia (SRID) has not been elucidated. Rapid changes in muscle strength are typically driven by short-term changes in muscle contractility or voluntary recruitment. The purpose of this study was to investigate how sleep restriction affects muscle contractile function and voluntary recruitment. Methods: A sample of 12 subjects (age 24.8 ± 2.6y) underwent isometric and isokinetic knee extensor muscle testing following 3d of adequate sleep (SA; 8.05 ± 0.45h), 3 d of sleep restriction (SR; 5.02 ± 0.05h), and 7d of washout (WO, 8.27 ± 0.50). The morning (7-11a local time) following the last day of each sleep period, subjects performed muscle strength testing using an isokinetic dynamometer. Subjects sat upright with the dominant leg secured at 60⁰ of knee flexion to optimize maximal quadriceps torque. They then performed 3 maximal voluntary isometric contractions (MVICs) of the quadriceps. Then subjects performed 6 submaximal contractions at 15, 30, 45, 60, 75, and 90% of the greatest MVIC. Next, subjects completed an interpolated twitch experiment while on the isokinetic dynamometer to assess voluntary activation. Finally, subjects completed 5 repetitions of isometric contractions, in descending order, at speeds of 300, 240, 180, 120, and 60 degree/s. From these methods we measured the highest MVIC, calculated the voluntary activation (VA), measured twitch properties, and compared the torque-EMG relationship. One-way repeated measures ANOVA were used to compare sleep, MVIC, and VA values, two-way (time x twitch property) repeated measures ANOVA was used to compare twitch properties and the torque-EMG relationship. Results: MVIC torque decreased following SR compared to SA before and after sleep restriction (SA: 217.1 ± 69.4 Nm vs. SR: 199.4 ± 67.1 Nm, p = 0.032). MVIC after WO (219.2 ± 54.2 Nm) was significantly greater than SR (p = 0.018) but was not significantly different from SA (p = 0.991). Although peak isokinetic torque decreased with increasing velocity (p < 0.001), there was no significant effect of sleep or sleep x speed interaction. Peak twitch torque and rate of torque
development, but not relaxation rate, were significantly greater in the potentiated state, but no significant effect of sleep or sleep x time interaction was noted. Sleep 3 condition did not significantly affect voluntary activation (SA: 86.3 ± 11.1% v. SR:86.6 ± 11.9% v. WO 87.7 ± 11.1%; p = 0.695). The torque output at various levels ofelectromyography (EMG) activity was not significantly different among sleep conditions (p = 0.383). The mean power frequency (MPF) of the VL was …
Investigation Of Lower Extremity Neuromuscular Function In Individuals With And Without Diabetes, Roya Hoveizavi
Investigation Of Lower Extremity Neuromuscular Function In Individuals With And Without Diabetes, Roya Hoveizavi
Theses and Dissertations--Kinesiology and Health Promotion
Background: Diabetes mellitus is associated with notable neuromuscular and motor dysfunctions that could lead to an increased risk of plantar ulcers and amputations. Several contributing factors, including increased muscle-tendon stiffness and abnormal muscle activation pattern may influence the kinematics and kinetics of walking in people with diabetes and promote formation of plantar ulcers. Hyperglycemia and the resultant accelerated rate of glycation have been recognized as the leading cause of muscle and tendon degeneration, yet the precise mechanisms by which diabetes affects the biomechanical properties of the muscle-tendon unit remains unclear. Altered muscle activity during gait is observed in people with …
Reliability And Validity Of A Commercial Running Power Meter To Indicate Metabolic Workload During Endurance Running, James Harris Hudgins Iii
Reliability And Validity Of A Commercial Running Power Meter To Indicate Metabolic Workload During Endurance Running, James Harris Hudgins Iii
Theses and Dissertations--Kinesiology and Health Promotion
Commercial running power (RP) meters may provide endurance runners and coaches with improved precision for monitoring running intensity. Cyclists rely upon the relationship between cycling power and metabolic demand to regulate physiological intensity during training and racing, independent of changes in the physical environment (e.g., terrain, wind). Research demonstrates strong reliability and validity for a specific RP meter to indicate metabolic demand within controlled running conditions. However, several potential influences on this relationship have not been investigated. Therefore, four studies were conducted with the following aims:
- Study 1: Determine the inter-limb reliability and validity of a single-limb-based RP meter …
The Effect Of Physical Activity Courses On The Motivation For Physical Activity In College Students: A Scoping Review, Erica Fauste Waizenhofer Hill
The Effect Of Physical Activity Courses On The Motivation For Physical Activity In College Students: A Scoping Review, Erica Fauste Waizenhofer Hill
Theses and Dissertations--Kinesiology and Health Promotion
The lack of physical activity and exercise participation has been an ongoing
problem for young adults aged 18-24. Universities and colleges worldwide offer a variety of required and elective physical activity courses for college credit to increase active participation in lifelong healthy lifestyles. This scoping review collected studies on college students’ motivation to participate in physical activity. The courses were taught using methods based on motivational theories. The authors of the studies collected information from the students before and after the classes to gather data on the theoretical framework’s effect on the students, if any. This review compiles this information, …
The Effects Of Cannabidiol Cream On Soreness And Performance After Exercise In Untrained Individuals, Joseph Thomas Pastina
The Effects Of Cannabidiol Cream On Soreness And Performance After Exercise In Untrained Individuals, Joseph Thomas Pastina
Theses and Dissertations--Kinesiology and Health Promotion
Background: Exercise-induced muscle damage (EIMD) results from unaccustomed exercise and can lead to delayed onset muscle soreness (DOMS). Impairments associated with EIMD and DOMS can result in moderate-to-severe discomfort and hindered performance. Recently, a compound derived from the cannabis plant, cannabidiol (CBD), has been used as a recovery tool for EIMD and DOMS. Despite the rising popularity of CBD products, their effectiveness in mitigating EIMD and DOMS is unknown. Purpose: The purpose of the present study was to investigate the effects of CBD cream on DOMS and performance after an intensive lower-body exercise protocol. In addition, the study sought to …
The Effects Of Saddle Angle/Inclination On Lumbopelvic Kinematics And Cardiometabolic Measures, Andrew Nathan Anderson
The Effects Of Saddle Angle/Inclination On Lumbopelvic Kinematics And Cardiometabolic Measures, Andrew Nathan Anderson
Theses and Dissertations--Kinesiology and Health Promotion
Lower back pain (LBP) is a condition which affects the lumbar portion of the spinal column that can lead to mild to extreme physical pain during seated tasks and has been shown to be prevalent in people who spend long durations sitting particularly in a slumped position or in a position with a large degree of lumbar flexion. LBP can cause regular interruptions in work and in a person’s ability to engage in exercise, and in most extreme cases warrants surgical interventions for clinical treatment. While LBP is prevalent in sedentary populations, it is also quite prevalent in cycling populations …
Kentucky Teacher Social-Emotional Competence, Burnout, And School Climate, Monica Mundy
Kentucky Teacher Social-Emotional Competence, Burnout, And School Climate, Monica Mundy
Theses and Dissertations--Kinesiology and Health Promotion
Teachers are tasked with supporting student learning and academic achievement. Teachers must establish social-emotional competence within themselves to support students' social-emotional learning. Increased teachers' social-emotional competence could lead to favorable student social, emotional, and academic outcomes. To effectively do so, school officials, parents, and community members should support teachers' social-emotional competence equally.
This study examined the relationship between Kentucky teachers' social-emotional competence, burnout, and school climate. The prosocial classroom model provided the theoretical framework for this study, including the five dimensions of social-emotional competence (self-awareness, self-management, social awareness, relationship skills, and responsible decision-making), teacher burnout, and school climate. The hypothesis …
Methodolocical Concerns Of Using Global Positioning System Technology To Assess American Football Competition Demands, Tyler Lindon
Methodolocical Concerns Of Using Global Positioning System Technology To Assess American Football Competition Demands, Tyler Lindon
Theses and Dissertations--Kinesiology and Health Promotion
Despite its popularity, there is a lack of research describing the physical demands of American Football. This is surprising when considering the popularity of the use of global positioning systems (GPS) within this specific sporting environment. The aim of the present study was to utilize a novel methodology to describe the physical demands of American football players by play type (run vs. pass) using a play-by-play analysis of global positioning system (GPS) outcomes. Fifty Division I collegiate American football players (Age: 19.8 ± 1.1 yr, Height: 189.3 ± 4.4 cm, Body mass: 86.1 ± 5.8 kg) wore portable GPS monitors …
Defining Sagittal Plane Gait Mechanics And Joint Loading In People With Marfan Syndrome, Justin Melan Pol
Defining Sagittal Plane Gait Mechanics And Joint Loading In People With Marfan Syndrome, Justin Melan Pol
Theses and Dissertations--Biomedical Engineering
Marfan syndrome (MFS) is a genetic condition that is associated with altered muscle composition, which leads to muscle dysfunction. People with MFS exhibit high instances of lower extremity (LE) joint pain that inhibits their ability to perform activities of daily living, such as walking. Despite these detrimental impacts of MFS, there have been no attempts to characterize the effects of MFS on LE joint loading and health during walking that are associated with LE pain and dysfunction. As people with MFS exhibit a high incidence rate of osteoarthritis (OA), the need to understand the potential alterations in LE extremity mechanics …
3-Dimensional Muscle Constructs: Using Hydrogels In Order To Model The Effects Of Exercise In Disease Conditions, Mark Mchargue
3-Dimensional Muscle Constructs: Using Hydrogels In Order To Model The Effects Of Exercise In Disease Conditions, Mark Mchargue
Theses and Dissertations--Biomedical Engineering
Currently, there is no standard in vitro model for studying the effects of mechanical stimulation on muscle in type II diabetes. Existing models primarily utilize electrical stimulation, which does not fully recapitulate the effects of exercise. In this thesis, we create a standardized in vitro model of murine muscle that can recapitulate the benefits seen in exercise when mechanically stimulated. Moreover, we show that a type II diabetes environment has similar effects on the muscle in vitro as well as in vivo.
Multiscale And Multimodality Optical Imaging Of Brain Hemodynamics And Function, Mehrana Mohtasebi
Multiscale And Multimodality Optical Imaging Of Brain Hemodynamics And Function, Mehrana Mohtasebi
Theses and Dissertations--Biomedical Engineering
Frequent measurement of cerebral hemodynamics is crucial for continuous assessment of brain function and health. Low-frequency oscillations (LFOs; < 0.1 Hz) have shown promise as an indicator of altered neurologic activity in the abnormal brain. Moreover, quantification of temporal correlations in LFOs across distinct brain regions enables mapping of regional neurovascular disorders. Portable diffuse optical techniques such as near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS) enable noninvasive and continuous measurements of cerebral oxygenation and cerebral blood flow (CBF), respectively. However, most NIRS/DCS systems use limited numbers of discrete light sources and detectors and thus lack combinations of high temporal/spatial resolution and large field-of-view (FOV) for brain imaging. Recent development of an innovative noncontact speckle contrast diffuse correlation tomography (scDCT) in our lab provides a low-cost and portable tool for high-density imaging of CBF distributions over large FOVs. The scDCT uses a galvo-mirror to remotely deliver coherent point near-infrared light to multiple source positions and a CMOS camera as a high-density 2-D detector array to quantify spatial fluctuations of diffuse laser speckles, resulting from movement of red blood cells. Boundary CBF data were input to a unique finite-element-method (FEM)-based reconstruction algorithm for 3-D imaging of CBF distributions. However, scDCT was hindered for extracting LFOs due to its low sampling rate. In this study, scDCT was optimized to achieve high sampling rates and fast image reconstructions by use of moving window algorithms with parallel computations (Project 1). Power spectral density (PSD) analysis was performed to investigate altered LFOs during transient cerebral ischemia in neonatal piglets. Transient cerebral ischemia caused reductions in both CBF and PSD, supporting inclusion of scDCT in the growing field of LFO analysis. One remaining limitation was the long computational time required for 3-D reconstruction, which prohibited real-time applications. To overcome this limitation, a depth-sensitive diffuse speckle contrast topography (DSCT) method was developed for analyzing scDCT data to achieve fast and high-density 2-D mapping of CBF distribution without the need of complex and time-consuming 3-D reconstructions (Project 2). New head-simulating phantoms with known optical/geometric properties were designed and fabricated to evaluate the spatial resolution and depth sensitivity of DSCT method. In-vivo experiments verified the capability of DSCT in tracking dynamic changes in CBF at different depths during CO2 inhalation and transient cerebral ischemia in rats. In addition to preclinical studies, a low-cost, wearable, fluorescence eye loupe (FLoupe) device was invented for intraoperative visualization of brain tumor margin in the clinic (Project 3). Consistent results were observed against an expensive, large, standard fluorescence operative microscope for the guidance of tumor resection. Overall, through 3 projects this dissertation demonstrated a variety of noninvasive noncontact optical technologies (scDCT, DSCT, and FLoupe) that enabled multiscale (rodents, piglets, and humans) and …
A Wearable Fiber-Free Optical Sensor For Continuous Measurements Of Cerebral Blood Flow And Oxygenation, Xuhui Liu
Theses and Dissertations--Biomedical Engineering
Wearable technologies for continuous monitoring of cerebral hemodynamics in freely behaving subjects not only advance our understanding of cognitive processing and adaptive behavior, but also provide vital information for diagnosis and therapeutic assessment of cerebral diseases associated with hypoxia/ischemia. Wearable near-infrared diffuse optical techniques have been used at the bedside to probe deep cerebral hemodynamics, including near-infrared spectroscopy (NIRS) for cerebral oxygenation measurement and diffuse correlation spectroscopy (DCS) for cerebral blood flow (CBF) measurement, respectively. However, most systems are relatively large and expensive, and use rigid fiber-optic probes that significantly constrain subject’s movement. A novel, wearable, fiber-free diffuse speckle contrast …
Quantitative Microbial Risk Assessment (Qmra) For Urban Stormwater Reuse After Treatment Through A Bioretention System, Isaac Oluk
Theses and Dissertations--Civil Engineering
Bioretention, also referred to as a stormwater biofilter, is an extensively used low-impact development technology for both stormwater management and water quality gains. However, little attention has been paid to the acceptability and uncertainty of human health risks associated with the treatment performance of bioretention filter media, and non-potable water reuse scenarios to guide decision-making and system design. This study uses bioretention mechanistic modeling paired with quantitative microbial risk assessment (QMRA) under uncertainty to evaluate human health risks from two reference pathogens – Campylobacter jejuni and Cryptosporidium. Consumption of irrigated green salad, consumption of raw green salad washed with effluent, …
Do Transportation Network Companies Affect Road Safety Outcomes: A Spatially Detailed Analysis In San Francisco, Vedant Shriniwas Goyal
Do Transportation Network Companies Affect Road Safety Outcomes: A Spatially Detailed Analysis In San Francisco, Vedant Shriniwas Goyal
Theses and Dissertations--Civil Engineering
US traffic fatal deaths have steadily risen since 2010, with the past few years witnessing an unusual trend increase. To reverse such a dangerous trend, one must understand how and why road crashes occur and which factors are causing them. Emerging transportation technologies have shown the potential to improve mobility and safety. However, such technologies are not inherently beneficial and could worsen road safety if not effectively implemented. One such transportation technology that warrants investigation is the rise of ridesharing services, also called Transportation Network Companies (TNCs). The primary goal of the dissertation is to explore the statistical relationship between …
Prediction Of Chlorine And Disinfection Byproduct Concentration In Water Distribution Systems Using Kypipe And Tthm Regression Models: Application To Two Systems In Kentucky, Yogesh Gautam
Theses and Dissertations--Civil Engineering
The main objective of this research is to study if the hydraulic and water quality models can be used for water quality analysis of chlorine decay and TTHM formation at various locations across a water distribution system. This is particularly important because it is not always easy or economical to take multiple field samples and analyze them in the laboratory. In this study, models of two different water distribution systems (one more urban and efficiently managed system located in a relative flat topography, and other more rural and less efficiently managed system located in a mountainous topography) were developed in …