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Pioglitazone Induces Apoptosis Of Macrophages In Human Adipose Tissue, Angela M. Bodles, Vijayalakshmi Varma, Aiwei Yao-Borengasser, Bounleut Phanavanh, Charlotte A. Peterson, Robert E. Mcgehee Jr., Neda Rasouli, Martin Wabitsch, Philip A. Kern Jan 2006

Pioglitazone Induces Apoptosis Of Macrophages In Human Adipose Tissue, Angela M. Bodles, Vijayalakshmi Varma, Aiwei Yao-Borengasser, Bounleut Phanavanh, Charlotte A. Peterson, Robert E. Mcgehee Jr., Neda Rasouli, Martin Wabitsch, Philip A. Kern

Clinical and Translational Science Faculty Publications

Metabolic syndrome and type 2 diabetes mellitus are associated with an increased number of macrophage cells that infiltrate white adipose tissue (WAT). Previously, we demonstrated that the treatment of subjects with impaired glucose tolerance (IGT) with the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone resulted in a decrease in macrophage number in adipose tissue. Here, adipose tissue samples from IGT subjects treated with pioglitazone were examined for apoptosis with terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) staining. TUNEL-positive cells were identified, and there was a significant 42% increase in TUNEL-positive cells following pioglitazone treatment. Overlay experiments with anti-CD68 antibody …

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Generalized Geologic Map For Land-Use Planning: Nelson County, Kentucky, Stephen F. Greb, Bart Davidson, Daniel I. Carey Jan 2006

Generalized Geologic Map For Land-Use Planning: Nelson County, Kentucky, Stephen F. Greb, Bart Davidson, Daniel I. Carey

Map and Chart--KGS

This map is not intended to be used for selecting individual sites. Its purpose is to inform land-use planners, government officials, and the public in a general way about geologic bedrock conditions that affect the selection of sites for various purposes. The properties of thick soils may supercede those of the underlying bedrock and should be considered on a site-to-site basis. At any site, it is important to understand the characteristics of both the soils and the underlying rock.

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Generalized Geologic Map For Land-Use Planning: Mercer County, Kentucky, Daniel I. Carey, Peter Eclov Jan 2006

Generalized Geologic Map For Land-Use Planning: Mercer County, Kentucky, Daniel I. Carey, Peter Eclov

Map and Chart--KGS

This map is not intended to be used for selecting individual sites. Its purpose is to inform land-use planners, government officials, and the public in a general way about geologic bedrock conditions that affect the selection of sites for various purposes. The properties of thick soils may supercede those of the underlying bedrock and should be considered on a site-to-site basis. At any site, it is important to understand the characteristics of both the soils and the underlying rock.

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Generalized Geologic Map For Land-Use Planning: Marion County, Kentucky, Daniel I. Carey, Garland R. Dever Jr., Adam Pike Jan 2006

Generalized Geologic Map For Land-Use Planning: Marion County, Kentucky, Daniel I. Carey, Garland R. Dever Jr., Adam Pike

Map and Chart--KGS

This map is not intended to be used for selecting individual sites. Its purpose is to inform land-use planners, government officials, and the public in a general way about geologic bedrock conditions that affect the selection of sites for various purposes. The properties of thick soils may supercede those of the underlying bedrock and should be considered on a site-to-site basis. At any site, it is important to understand the characteristics of both the soils and the underlying rock.

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Generalized Geologic Map For Land-Use Planning: Pike County, Kentucky, Richard A. Smath, Daniel I. Carey, Bart Davidson, Alex W. Fogle Jan 2006

Generalized Geologic Map For Land-Use Planning: Pike County, Kentucky, Richard A. Smath, Daniel I. Carey, Bart Davidson, Alex W. Fogle

Map and Chart--KGS

This map is not intended to be used for selecting individual sites. Its purpose is to inform land-use planners, government officials, and the public in a general way about geologic bedrock conditions that affect the selection of sites for various purposes. The properties of thick soils may supercede those of the underlying bedrock and should be considered on a site-to-site basis. At any site, it is important to understand the characteristics of both the soils and the underlying rock.

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Can Corporations Be Held Liable Under The Alien Tort Claims Act?, Kelsy Deye Jan 2006

Can Corporations Be Held Liable Under The Alien Tort Claims Act?, Kelsy Deye

Kentucky Law Journal

No abstract provided.

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Assessment Of Water Quality Trends In The Upper Cumberland River Basin: Focus On Pathogen Impairment, Kentucky Water Resources Institute Jan 2006

Assessment Of Water Quality Trends In The Upper Cumberland River Basin: Focus On Pathogen Impairment, Kentucky Water Resources Institute

KWRRI Research Reports

This project consisted of analyzing existing water quality data for streams in the Upper Cumberland River Basin, with a particular focus on pathogen trends. According to the most recent 303(d) list of Kentucky waters, the majority of streams assessed in the Upper Cumberland Basin are impaired for primary recreational contact as a result of pathogens. The state pathogen standard for primary contact recreation is expressed in a dual form which specifies that the 30-day geometric mean of fecal coliform counts not exceed 200 colonies per 100 mL (on a minimum of five samples) and not more than 20 percent of …

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Kentucky Water Resources Research Institute Annual Technical Report Fy 2005, Kentucky Water Resources Research Institute, University Of Kentucky Jan 2006

Kentucky Water Resources Research Institute Annual Technical Report Fy 2005, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The 2005 Annual Technical Report for Kentucky consolidates reporting requirements of the Section 104(b) base grant award in a single technical report that includes: 1) a synopsis of each research project supported during the period, 2) related reports and publications, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable achievements and awards during the year.

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2006 Kentucky River Watershed Watch Sampling Results, Malissa Mcalister, Lindell Ormsbee Jan 2006

2006 Kentucky River Watershed Watch Sampling Results, Malissa Mcalister, Lindell Ormsbee

Kentucky River Watershed Watch

No abstract provided.

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South Korea's National Security Law: A Tool Of Oppression In An Insecure World, Diane B. Kraft Jan 2006

South Korea's National Security Law: A Tool Of Oppression In An Insecure World, Diane B. Kraft

Law Faculty Scholarly Articles

In September 2004, the ruling party in South Korea, along with two opposition parties, called for the abolishment of the 1948 anti-communist National Security Law. The following month, Amnesty International, a long-time critic of the law, officially called for the law's repeal. The law had been enacted in 1948 in response to threats from communist North Korea, but has long been used by the government to silence legitimate opposition in South Korea. This Comment will examine South Korea's National Security Law as viewed by its domestic supporters and critics, as well as by the international community. Part I will consider …

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Turning Jails Into Prisons—Collateral Damage From Kentucky's War On Crime, Robert G. Lawson Jan 2006

Turning Jails Into Prisons—Collateral Damage From Kentucky's War On Crime, Robert G. Lawson

Law Faculty Scholarly Articles

The primary purpose of this article is to scrutinize Kentucky's ever-increasing reliance on local jails for the incarceration of state prisoners. This objective cannot be achieved without an examination of the problems that compel counties and cities to allow (and even encourage) the state to capture their jails for this use. The first half of the article (Parts I-IV) provides general information about jails (including some pertinent history), contains a detailed description of jail functions (including some that have descended upon jails by default), and concludes with a discussion of what the state has done over two decades to convert …

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Nlm Database Central: The First Place To Look For Your Phsr Research Data, F. Douglas Scutchfield Md Jan 2006

Nlm Database Central: The First Place To Look For Your Phsr Research Data, F. Douglas Scutchfield Md

Preventive Medicine and Environmental Health Presentations

No abstract provided.

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Self-Regulation For Safety And Security: Final Minutes Or Finest Hour?, Douglas C. Michael Jan 2006

Self-Regulation For Safety And Security: Final Minutes Or Finest Hour?, Douglas C. Michael

Law Faculty Scholarly Articles

The terrorist attacks of September 11, 2001, and the accounting and auditing crisis later caused by the Enron and Worldcom scandals of that same year, created a great sense of insecurity in many Americans. In this Article, I analyze the federal government's response to crisis. I first define what a crisis is: a sudden, existential threat to which the entity has insufficient resources to respond. I then explain how regulation for safety and security is unique in two aspects: perceptions matter, and the assistance of the regulated entities is essential. I proceed by describing and analyzing the regulatory history and …

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A Hypermedia Simulation That Teaches Defensive Driving Skills, Borchyi Lin Jan 2006

A Hypermedia Simulation That Teaches Defensive Driving Skills, Borchyi Lin

University of Kentucky Doctoral Dissertations

Because of increased commuter traffic volume on rural roadways collisions between motor vehicles and farm equipment have increased in frequency and severity over the last several years. This study investigated the effects of a multimedia narrative simulation program that taught hazard recognition and promoted defensive driving on rural roadways shared by farm equipment. A companion animated driving game allowed users to practice reaction/stopping time distances with a simulated automobile on a simulated highway when objects appeared suddenly in the path of the automobile. The program and game were delivered by an objective-oriented client/server computer program that also recorded and stored …

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Automatic Detection Of Sleep And Wake States In Mice Using Piezoelectric Sensors, Dharshan C. Medonza Jan 2006

Automatic Detection Of Sleep And Wake States In Mice Using Piezoelectric Sensors, Dharshan C. Medonza

University of Kentucky Master's Theses

Currently technologies such as EEG, EMG and EOG recordings are the established methods used in the analysis of sleep. But if these methods are to be employed to study sleep in rodents, extensive surgery and recovery is involved which can be both time consuming and costly. This thesis presents and analyzes a cost effective, non-invasive, high throughput system for detecting the sleep and wake patterns in mice using a piezoelectric sensor. This sensor was placed at the bottom of the mice cages to monitor the movements of the mice. The thesis work included the development of the instrumentation and signal …

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The Speciation Of Metals In Mammals Influences Their Toxicokinetics And Toxicodynamics And Therefore Human Health Risk Assessment, Robert A. Yokel, Stephen M. Lasley, David C. Dorman Jan 2006

The Speciation Of Metals In Mammals Influences Their Toxicokinetics And Toxicodynamics And Therefore Human Health Risk Assessment, Robert A. Yokel, Stephen M. Lasley, David C. Dorman

Pharmaceutical Sciences Faculty Publications

Chemical form (i.e., species) can influence metal toxicokinetics and toxicodynamics and should be considered to improve human health risk assessment. Factors that influence metal speciation (and examples) include: (1) carrier-mediated processes for specific metal species (arsenic, chromium, lead and manganese), (2) valence state (arsenic, chromium, manganese and mercury), (3) particle size (lead and manganese), (4) the nature of metal binding ligands (aluminum, arsenic, chromium, lead, and manganese), (5) whether the metal is an organic versus inorganic species (arsenic, lead, and mercury), and (6) biotransformation of metal species (aluminum, arsenic, chromium, lead, manganese and mercury). The influence of speciation on metal …

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Generalized Geologic Map For Land-Use Planning: Clark County, Kentucky, Daniel I. Carey, Emma Witt Jan 2006

Generalized Geologic Map For Land-Use Planning: Clark County, Kentucky, Daniel I. Carey, Emma Witt

Map and Chart--KGS

This map is not intended to be used for selecting individual sites. Its purpose is to inform land-use planners, government officials, and the public in a general way about geologic bedrock conditions that affect the selection of sites for various purposes. The properties of thick soils may supercede those of the underlying bedrock and should be considered on a site-to-site basis. At any site, it is important to understand the characteristics of both the soils and the underlying rock.

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Generalized Geologic Map For Land-Use Planning: Bourbon County, Kentucky, Daniel I. Carey Jan 2006

Generalized Geologic Map For Land-Use Planning: Bourbon County, Kentucky, Daniel I. Carey

Map and Chart--KGS

This map is not intended to be used for selecting individual sites. Its purpose is to inform land-use planners, government officials, and the public in a general way about geologic bedrock conditions that affect the selection of sites for various purposes. The properties of thick soils may supercede those of the underlying bedrock and should be considered on a site-to-site basis. At any site, it is important to understand the characteristics of both the soils and the underlying rock.

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Treading On Hallowed Ground: Implications For Property Law And Critical Theory Of Land Associated With Human Death And Burial, Mary L. Clark Jan 2006

Treading On Hallowed Ground: Implications For Property Law And Critical Theory Of Land Associated With Human Death And Burial, Mary L. Clark

Kentucky Law Journal

No abstract provided.

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Gouging: Terrorist Attacks, Hurricanes, And The Legal And Economic Aspects Of Post-Disaster Price Regulation, Geoffrey C. Rapp Jan 2006

Gouging: Terrorist Attacks, Hurricanes, And The Legal And Economic Aspects Of Post-Disaster Price Regulation, Geoffrey C. Rapp

Kentucky Law Journal

No abstract provided.

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The Audit Committee "Financial Expert" Requirement And The Internal Control Attestation: Effective Contributions To Corporate Governance?, Joseph A. Guillory Jan 2006

The Audit Committee "Financial Expert" Requirement And The Internal Control Attestation: Effective Contributions To Corporate Governance?, Joseph A. Guillory

Kentucky Law Journal

No abstract provided.

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Turning Jails Into Prisons--Collateral Damage From Kentucky's "War On Crime", Robert G. Lawson Jan 2006

Turning Jails Into Prisons--Collateral Damage From Kentucky's "War On Crime", Robert G. Lawson

Kentucky Law Journal

No abstract provided.

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Employee Threshold On Federal Antidiscrimination Statutes: A Matter Of The Merits, Christine Neylon O'Brien, Stephanie Greene Jan 2006

Employee Threshold On Federal Antidiscrimination Statutes: A Matter Of The Merits, Christine Neylon O'Brien, Stephanie Greene

Kentucky Law Journal

No abstract provided.

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Air Exchange Rate In A Horse Trailer During Road Transport, Joseph L. Purswell, Richard S. Gates, Laurie M. Lawrence, Jamey D. Jacob, Timothy S. Stombaugh, Robert J. Coleman Jan 2006

Air Exchange Rate In A Horse Trailer During Road Transport, Joseph L. Purswell, Richard S. Gates, Laurie M. Lawrence, Jamey D. Jacob, Timothy S. Stombaugh, Robert J. Coleman

Biosystems and Agricultural Engineering Faculty Publications

Horses traveling by road commonly experience heat stress conditions and poor air quality, which may be caused by insufficient ventilation; however, there are few estimates of air exchange in a horse trailer during transport. Air exchange rate was measured at ten locations within a four-horse trailer (internal volume 18.5 m3) using tracer gas decay measurement to assess the adequacy of ventilation. Three vehicle speeds (13, 48, and 97 km h-1) and three window configurations (all windows and roof vents closed, all windows open, all windows open and roof vents open forward) were tested with and without …

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Online Story Comprehension Among Children With Adhd: Which Core Deficits Are Involved?, Kate Flory, Richard Milich, Elizabeth P. Lorch, Angela N. Hayden, Chandra Strange, Richard Welsh Jan 2006

Online Story Comprehension Among Children With Adhd: Which Core Deficits Are Involved?, Kate Flory, Richard Milich, Elizabeth P. Lorch, Angela N. Hayden, Chandra Strange, Richard Welsh

Psychology Faculty Publications

Children with ADHD have difficulty understanding causal connections and goal plans within stories. This study examined mediators of group differences in story narrations between children ages 7-9 with and without ADHD, including as potential mediators both the core deficits of ADHD (i.e., inattention, disinhibition, planning/working memory) as well measures of phonological processing and verbal skills. Forty-nine children with ADHD and 67 non-referred children narrated a wordless book and completed tasks assessing the core deficits of ADHD, phonological processing, and verbal skills. Results revealed that, although no shorter than those of non-referred children, the narratives of children with ADHD contained fewer …

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Products Liability In The Twenty-First Century: A Review Of Owen’S Products Liability Law, Richard C. Ausness Jan 2006

Products Liability In The Twenty-First Century: A Review Of Owen’S Products Liability Law, Richard C. Ausness

Law Faculty Scholarly Articles

Professor Richard C. Ausness reviews Products Liability Law, a treatise by David Owen.

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Entropy Of Electroencephalogram (Eeg) Signals Changes With Sleep State, Blesy Anu Mathew Jan 2006

Entropy Of Electroencephalogram (Eeg) Signals Changes With Sleep State, Blesy Anu Mathew

University of Kentucky Master's Theses

We hypothesized that temporal features of EEG are altered in sleep apnea subjects comparedto normal subjects. The initial aim was to develop a measure to discriminate sleep stages innormals. The longer-term goal was to apply these methods to identify differences in EEGactivity in sleep apnea subjects from normals. We analyzed the C3A2 EEG and anelectrooculogram (EOG) recorded from 9 normal adults awake and in rapid eye movement(REM) and non-REM sleep. The EEG signals were filtered to remove EOG contamination. Twomeasures of the irregularity of EEG signals, Sample Entropy (SpEn) and Tsallis Entropy, wereevaluated for their ability to discriminate sleep stages. …

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Posttraumatic Growth And Ptsd Symptomatology Among Colorectal Cancer Survivors: The Impact Of Emotional Expression And Cognitive Processing, John M. Salsman Jan 2006

Posttraumatic Growth And Ptsd Symptomatology Among Colorectal Cancer Survivors: The Impact Of Emotional Expression And Cognitive Processing, John M. Salsman

University of Kentucky Doctoral Dissertations

There are substantial data exploring the link between religiosity and health, yet there is no consensus regarding the appropriate measurement tool for assessing religiosity in health psychology settings. The purpose of this study was to identify a set of items that could serve as a reliable and valid proxy measure of religiosity. Participants included 251 (M=19.02; range = 17-25) young adults who completed self-report measures of religiosity (Intrinsic-Extrinsic/Revised, Quest Scale, Faith Maturity Scale), psychological distress (SCL-90-R), and personality (NEOPI-R). Individual item pools for religiosity were developed by identifying significant correlations between each of the religiosity measures and the SCL-90-R items. …

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The Changing Relationships Of Women Helping Women: Patterns And Trends In Domestic Violence Advocacy, Jennifer Rose Wies Jan 2006

The Changing Relationships Of Women Helping Women: Patterns And Trends In Domestic Violence Advocacy, Jennifer Rose Wies

University of Kentucky Doctoral Dissertations

This research explores the themes of participation and professionalization as they intersect with power in domestic violence advocacy by using a case study from one region in Kentucky. Throughout this dissertation, I investigate the ways political and economic pressures influence local domestic violence advocates and the ways these macro-level pressures influence 1) an advocate's level of participation in the organization and 2) a transition in social service provision to a professional model of advocacy. The research illustrates that the nature of domestic violence service provision is changing in the United States as a result of the increasingly privatized nature of …

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Information System Contextual Data Quality: A Case Study, Daniel Lee Davenport Jan 2006

Information System Contextual Data Quality: A Case Study, Daniel Lee Davenport

University of Kentucky Doctoral Dissertations

This dissertation describes a case study comparing the effectiveness of twoinformation systems that assess the quality of surgical care, the National SurgicalQuality Improvement Program (NSQIP) and the University HealthSystemConsortium Clinical Database (UHCCD). For the comparison, it develops aframework for assessing contextual data quality (CDQ) from the decision maker'sperspective. The differences in quality assessment systems to be studied areposited to be due to the differing contexts in which the data is encoded,transformed and managed impacting data quality for the purpose of surgicalquality assessment.Healthcare spending in the United States has risen faster than the rate of inflationfor over a decade and currently …

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