Digital Commons Network^™

Rural And Urban Clinician Views On Covid- 19’S Impact On Substance Use Treatment For Individuals On Community Supervision In Kentucky, Carrie B. Oser, Maria Rockett, Sebastian Otero, Evan Batty, Marisa Booty, Rachel Gressick, Michele Staton, Hannah K. Knudsen

Center on Drug and Alcohol Research Faculty Publications

Background The COVID-19 pandemic produced system-level changes within the criminal legal system and community-based substance use disorder (SUD) treatment system with impacts on recovery efforts. This study examines rural and urban clinicians’ perspectives of COVID-19 on SUD treatment delivery for people on community supervision.

Methods Virtual qualitative interviews were conducted between April and October 2020 with 25 community supervision clinicians employed by Kentucky’s Department of Corrections (DOC), who conduct assessments and facilitate community-based treatment linkages for individuals on probation or parole. Transcripts were analyzed in NVivo using directed content analysis methods.

Results Clinicians were predominantly white (92%) and female (88%) …

A Change Of Character? Exploring The Possible Effects Of Non-Tenure Track Faculty At Liberal Arts Colleges, Robert Brown

Theses and Dissertations--Educational Policy Studies and Evaluation

Research on liberal arts colleges (LACs) has yet to consider possible effects of using Non-Tenure Track Faculty (NTTF) on the character of LACs. LACs are characterized by their strong academic ethos, collegial faculty-student relationships, all at a sanctuary-like setting. Tenure Track Faculty (TTF) and administrators at three LACs were interviewed in a case study format at an urban, suburban, and rural LAC to consider whether NTTF are affecting the character of such institutions. NTTF, especially when full-time faculty, support the academic ethos, foster strong student faculty relationships, and help maintain the sanctuary like setting. NTTF use by change agents is …

Impact Of Augmented Documentation Workflows On Transportation Agency Asphalt Paving Operations: A Qualitative And Quantitative Study, Josh Withrow

Theses and Dissertations--Civil Engineering

e-Ticketing was an intriguing technology to many state transportation agencies (STAs) pre-COVID-19 pandemic but gained significant attention upon arrival of the pandemic due to the contactless nature of the technology. Research completed prior to the pandemic into e-ticketing for asphalt paving primarily identified qualitative benefits and concerns. However, minimal academic literature exists in the post-pandemic era discussing the additional e-ticketing benefits not previously captured which resulted in increased implementation by STAs. This research seeks to address this gap by gathering information from state members of the American Association of State Highway and Transportation Officials Committee on Construction (AASHTO COC), employees …

Analysis And Improvement Of The Kentucky Transportation Cabinet’S Serious Injury And Fatality Program, Arun Subedi

Theses and Dissertations--Civil Engineering

Serious Injuries and Fatalities (SIFs) within construction and maintenance industries indicate severe vulnerabilities within workplace safety, and their prevention requires the highest priority. SIFs usually occur due to systemic failures, and proactive steps must be taken to identify and neutralize high-risk scenarios. Kentucky Transportation Cabinet (KYTC) has recently implemented a safety management system called BOOTS, for improving incident reporting and analysis along with SIFs. This study identifies gaps in KYTC's SIF reporting framework and provides analysis on recurring incident trends utilizing the incidents already reported in the system. While current practice in KYTC relies on event-based decision tree when classifying …

Digital Innovation Roadmap For Construction Industry: Bridging The Gap For Future, Nisa Zahin

Theses and Dissertations--Civil Engineering

Digitalization has considerable value in the digital transformation of the construction business. It means the use of digital technologies to create revenue, improve business, increase profit and sustainability, and create an environment for digital business whereby digital information is at the core. As such, digital transformation requires skills that involve extracting and exchanging data and analyzing and converting that data into actionable information. In addition to technological solutions, a paramount need is to ensure that the people using these solutions and the processes used to integrate, coordinate between teams, and continuously improve the use of technology are in place. Therefore, …

Advancing Combinatorial Screening Of Refractory High Entropy Alloys Through Intrinsic Ductility Assessment Via Thin Film Fragmentation Testing, Taohid Bin Nur Tuhser

Theses and Dissertations--Chemical and Materials Engineering

High Entropy Alloys (HEAs), also known as Multiprincipal Element Alloys (MPEAs), represent a paradigm shift in alloy design. Unlike traditional practices that limit compositions to the edges of phase diagrams, HEAs exploit equiatomic mixing of five or more elements at the center of phase diagrams to maximize configurational entropy. This unconventional approach exponentially expands the spectrum of potential alloy compositions, rendering conventional experimental methods inadequate for exploring this extensive compositional space.

In response to these challenges, the scientific community has shown a growing interest in high-throughput techniques, encompassing both computational and experimental domains. Particularly, Refractory High Entropy Alloys (RHEAs) have …

Language Models For Rare Disease Information Extraction: Empirical Insights And Model Comparisons, Shashank Gupta

Theses and Dissertations--Computer Science

End-to-end relation extraction (E2ERE) is a crucial task in natural language processing (NLP) that involves identifying and classifying semantic relationships between entities in text. This thesis compares three paradigms for end-to-end relation extraction (E2ERE) in biomedicine, focusing on rare diseases with discontinuous and nested entities. We evaluate Named Entity Recognition (NER) to Relation Extraction (RE) pipelines, sequence-to-sequence models, and generative pre-trained transformer (GPT) models using the RareDis information extraction dataset. Our findings indicate that pipeline models are the most effective, followed closely by sequence-to-sequence models. GPT models, despite having eight times as many parameters, perform worse than sequence-to-sequence models and …

The Dark Sides Of Giving: Representations Of Philanthropy And Gifts In Eighteenth-Century Literature, C.1750-1820, Jillian Winter

Theses and Dissertations--English

This dissertation explores representations of the gift in popular women’s novels of the long eighteenth century. Gift transactions in women’s fiction from this period reveal larger cultural reflections about the limitations placed on women who try to give and to help others. The primary works discussed in this project include Frances Burney’s Cecilia; or, Memoirs of an Heiress (1782), Eliza Haywood’s The History of Miss Betsy Thoughtless (1751), Mary Hays’s Memoirs of Emma Courtney (1796), Sarah Fielding’s The History of Ophelia (1760), and Maria Edgeworth’s Belinda (1801). Frequently, the novels considered in this dissertation showcase the complicated conditions, oftentimes troubling …

Writing White Women: White (Supremacist) Feminism In American Literature And Culture, Post Suffrage To Post Hillary (1920–2020s), Jannell C. Mcconnell Parsons

Theses and Dissertations--English

Recent critical texts by Jessie Daniels, Mikki Kendall, and more frame the histories of mainstream white feminism in ways that highlight its ongoing complicity with white supremacy and its maintenance of racist structures and systems. In conversation with these current scholarly as well as mainstream cultural conversations about white feminism that have been happening with more frequency since 2016, this project turns to post-suffrage narratives of white womanhood to historicize the modern narratives we tell about feminism’s history. Each chapter of this project considers a 1920s or 1930s literary narrative alongside current literary and cultural narratives as I explore the …

Recent Paleolimnological History Of Jackson Lake, Grand Teton National Park, Wyoming (Usa), Hillary Johnson

Theses and Dissertations--Earth and Environmental Sciences

This study utilizes a recently acquired, high-resolution CHIRP seismic reflection dataset and a deepwater sediment core to analyze the recent stratigraphy of Jackson Lake (Wyoming, USA). The western shoreline of Jackson Lake is situated adjacent to the Teton fault, a down-to-the-east normal fault that produces the spectacular high topography of Grand Teton National Park. The sediments of Jackson Lake are underexplored and consequently, their value as indicators of hydroclimatic and tectonic changes is unknown. Here, the sedimentary fill of Jackson Lake is explored as a natural archive of environmental change, specifically in reference to the influence of human outlet engineering …

Investigations Across Biology And Education: Exploring The Gut Microbiome Of Freshwater Mussels And Understanding Undergraduate Biology Student Motivation, Mary Foley

Theses and Dissertations--Biology

A PhD aims to make a unique contribution to the current body of knowledge while developing as an independent researcher and critical thinker. This dissertation covers a wide range of topics, from microbiome analysis to biology education. Although there is no broad overarching research theme, all the chapters are connected by the process of scientific inquiry and by their contribution to the completion of a PhD.

Chapter One serves as a comprehensive literature review, delving into the standard methods of measuring the health of at-risk species. It describes direct measures of health (e.g., birth and death rates) crucial for predicting …

Microstructural, Mineralogical, And Chemical Characterization Of The Handys Bend And Flax Creek Meteorites, Kentucky: Relevance For The Iron Meteorite Record, Ethan S.L. Davis

Theses and Dissertations--Earth and Environmental Sciences

Iron meteorites remain the only material view into planetary cores. Despite their scientific relevance, iron meteorites are relatively rare. In June 2021 and March 2022, the Kentucky Geological Survey received requests to identify two metallic specimens discovered in central Kentucky. The specimens were given the provisional names Handys Bend (3175.2 g) and Flax Creek (286.2 g). The goal of this project is to confirm meteoritic origin, characterize their structures and chemistry, assign genetic classifications, and examine potential relations to previous discoveries. Petrography was conducted using scanning electron microscopy. Mineral phases were examined using X-Ray diffraction crystallography. Chemical compositions were determined …

Assessing Microplastic Contamination Within Karst Groundwater Basins In Kentucky, Maaz Fareedi

Theses and Dissertations--Earth and Environmental Sciences

The input and abrasion of plastic waste in the environment has long been known to form microplastics (MPs). These ubiquitous contaminants are easily mobilized into hydrologic systems. MPs are now being found in karst aquifers around the world, including several across Kentucky, USA. Due to their size (< 5 mm in diameter), chemical properties, abundance, and wide distribution, MPs pose numerous ecological hazards, including uptake by organisms and as substrates for contaminant sorption. Karst groundwater is especially vulnerable to surface contaminants; however, knowledge of the extent of karst MP contamination is limited, with most studies focused on individual sites or small areas. In this study, we created a MP contamination dataset for 30 karst springs and 10 locations where cave sediments were characterized across Kentucky. MP concentrations in groundwater samples ranged from 0 to 41.1 items/L and yielded an average of 4.9 ± 8.7 items/L. Sediment MP concentrations ranged from 0 to 306 items/kg. We performed statistical analyses and linear regressions to examine whether groundwater MP concentrations could be explained by factors including land use, population density, basin area, numbers of sinkholes, and sinking streams. Our models revealed that population density, agrarian land use, sinking stream density, and basin area were related to MP concentrations. All factors except basin area trended positively with MP concentration, while basin area trended negatively. These relations are generally corroborated by existing literature, however they indicate that further studies with considerably larger sample sizes are needed to determine mechanistic relationships.

Visualizing And Automating Past, Real-Time, And Forecast Dynamic Hazard Maps For Shallow Colluvial Landslides In Eastern Kentucky, Nathaniel O'Leary

Theses and Dissertations--Earth and Environmental Sciences

Landslide hazards are a persistent threat to communities and infrastructure in Eastern Kentucky, where steep slopes, shallow colluvial soils, and variable hydrological conditions make slope failures frequent. This thesis presents an integrated approach to landslide hazard mapping (LHM) through the development of dynamic, spatiotemporal LHMs for shallow colluvial landslides. Two studies within this work investigate and refine the use of the Lu and Godt (2008) factor of safety (FS) equation to improve landslide predictions. The first study establishes a novel LHM workflow using Hydrus-1D to simulate soil moisture infiltration and fluctuations from precipitation and evapotranspiration (ET) data. This study also …

Sh-Wave Seismic-Reflection Efficiency Technique For Investigating The Wolf Island Fault, New Madrid Seismic Zone, Usa, Stephanie Vicroy

Theses and Dissertations--Earth and Environmental Sciences

The Reelfoot Fault within the New Madrid seismic zone has displacement at seismogenic depth to which the surface expression has unequal displacement. Previous work identified northeast-oriented transpressional fault strands northeast of a bend in the scarp as evidence for a through-going shear-zone, acting as potential accommodation for the observed strain imbalance. This investigation projected the trend of these faults to their intersection with an industry seismic survey at Wolf Island, Missouri, which exhibits a similarly structured faulted zone. We suggest this structure is the continuation of the through-going shear zone representing a previously unknown 22-km-long Quaternary-active fault that can affect …

All Eyes On The Spiny Mouse: An Investigation Into Acomys Dimidiatus As A Model For Retinal Biology And Regeneration, Jessica D. Bills

Theses and Dissertations--Biology

The retina is a complex tissue with six types of neurons, supported by an intrinsic glia cell, that work in concert to input a visual stimulus and relay a visual message to the brain. Efficient communication between neurons is vital to this process and each neuron plays a significant role in vision. When retinal neurons degenerate, that visual signal is lost. Degenerative eye diseases affect the neurons of the retina in millions of people world-wide and can ultimately lead to blindness. While treatments are evolving, most are designed to prevent further damage; the field has yet to piece together how …

Alteration Of Ultramafic Lamprophyres And Its Effect On Rare Earth Element Distribution In The Illinois-Ketucky Fluorspar District, Zachary O. Walton

Theses and Dissertations--Earth and Environmental Sciences

The ultramafic lamprophyres of the Illinois-Kentucky Fluorspar District (IKFD) have been identified as a potential domestic source of rare earth elements (REEs). The present distribution of the REEs and the role of the carbonate alteration in the distribution of the REEs is poorly understood. Petrographic and geochemical analyses were employed to determine the nature of the mantle source region and timing of the carbonate mineralization. Ratios of ¹⁴³Nd/¹⁴⁴Nd vs. ⁸⁷Sr/⁸⁶Sr demonstrate that in addition to the intrusion of primitive magma into the crust, a melt was generated from a mantle source region metasomatized by …

Beauty And The Anthropocene: On The Emancipatory Potential Of Experiences Of Beautiful Places In The Natural World, Matthew John

Theses and Dissertations--Geography

This dissertation investigates the proposition that beauty—specifically, experiences of beautiful places in the natural world—can contribute to the emancipation of modern persons (and thereby developed societies) from instrumental rationality, which is theorized as a major driver of contemporary socioecological crises of the Anthropocene. Buber’s concept of the I–Thou relation provides a framework for conceptualizing ideal non-instrumental relations. The project’s methodology, rooted in post-phenomenology, consisted of semi-structured remote interviews and four follow-up focus groups with 35 then current and recently former residents of Juneau, Alaska. Taken together, data confirm that experiences of beautiful places in the natural world can and do …

A Geography Of Transgender Belonging In Louisville, Kentucky, Lj Mcallister

Theses and Dissertations--Geography

Louisville, Kentucky is home to a surprisingly robust – and complex – transgender community. This study uses qualitative data from interviews, collaborative maps, and archival research to analyze a geography of belonging for transgender residents in the city. It discusses how the twelve participants negotiate their relationships with the conservative, “red” state of Kentucky, as well as the geographical decision-making they use to navigate Louisville’s many neighborhoods. Ultimately, this thesis draws attention to the ways in which prejudice shapes the landscape of belonging for transgender life in Derby City.

Beyond The Hands: Exploring Intersectional Identities Of Black American Sign Language Users, Tatum Turner

Theses and Dissertations--Linguistics

There is a significant gap in research related to the impact of intersectionality on linguistic identity performance among individuals negotiating multiple marginalized identities. This gap is especially significant among deaf Black and African American individuals who use the American Sign Language (ASL) variety deemed Black American Sign Language (BASL) (Hairston & Smith, 1983). This research aims to identify and discuss the use of the eight distinguishing features of BASL (McCaskill et al. 2011) as indexes of intersectional identities.

My data consists of videos sourced from YouTube, each chosen according to the following criteria: must have at least one self-identifying Black …

"Many Fabulous Stories And Idle Tales": The Intersection Of Elizabethan Political Gambits And Indigenous Erasure In The Early American Republic, Daniel Ryan Lewis

Theses and Dissertations--History

Welsh Indian Theory, originating in Elizabethan England, stated that a group of Welsh explorers settled in the Americas in the late 12^th century and intermarried with the Indigenous tribes, thereby explaining “advanced cultures” ranging from the Mississippians to the Aztec Empire. This act of erasure became rooted in Kentucky and the surrounding area in the 18^th and 19^th centuries; a series of prominent individuals from Kentucky in turn contributed to a growing body of false historical narratives that denied Indigenous Americans their cultural identities and connection their ancestral lands in the United States. With a 460-year trail …

Properties Of Skew-Polynomial Rings And Skew-Cyclic Codes, Kathryn Hechtel

Theses and Dissertations--Mathematics

A skew-polynomial ring is a polynomial ring over a field, with one indeterminate x, where one must apply an automorphism to commute coefficients with x. It was first introduced by Ore in 1933 and since the 1980s has been used to study skew-cyclic codes. In this thesis, we present some properties of skew-polynomial rings and some new constructions of skew-cyclic codes. The dimension of a skew-cyclic code depends on the degree of its generating skew polynomial. However, due to the skew-multiplication rule, the degree of a skew polynomial can be smaller than its number of roots and hence tricky to …

Dirichlet Problems In Perforated Domains, Robert Righi

Theses and Dissertations--Mathematics

We establish W^1,p estimates for solutions u_ε to the Laplace equation with Dirichlet boundary conditions in a bounded C¹ domain Ω_{ε, η} perforated by small holes in ℝ^d. The bounding constants will depend explicitly on epsilon and eta, where epsilon is the order of the minimal distance between holes, and eta denotes the ratio between the size of the holes and epsilon. The proof relies on a large-scale L^p estimate for ∇u_ε, whose proof is divided into two main parts. First, we show that solutions of an intermediate problem for a …

A Multiple-Case Study On The Impact Of An Introductory Real Analysis Course On Undergraduate Students' Understanding Of Function Continuity, Ryan Joseph Rogers

Theses and Dissertations--Mathematics

Undergraduate students' understanding of function continuity has not been explored broadly in previous research. The relevant findings in the literature are predominantly concerned with calculus students' understanding and misconceptions of continuity. Many of these misunderstandings are tied to the relationships which continuity has with limits and differentiability. This multiple-case study explores how, if at all, an introductory real analysis course impacts undergraduate students' understanding of function continuity and its connections to the notions of limits and differentiability. We embed our findings within the theoretical framework of Tall's three worlds of mathematics, namely, the embodied, symbolic, and formal worlds.

The cases …

Advanced Mathematical Graph-Based Machine Learning And Deep Learning Models For Drug Design, Farjana Tasnim Mukta

Theses and Dissertations--Mathematics

Drug discovery is a highly complicated and time-consuming process. One of the main challenges in drug development is predicting whether a drug-like molecule will interact with a specific target protein. This prediction accelerates target validation and drug development. Recent research in biomolecular sciences has shown significant interest in algebraic graph-based models for representing molecular complexes and predicting drug-target binding affinity. In this thesis, we present algebraic graph-based molecular representations to create data-driven scoring functions (SF) using extended atom types to capture wide-range interactions between targets and drug candidates. Our model employs multiscale weighted colored subgraphs for the protein-ligand complex, colored …

Evaluating The Early Impacts Of The Snap Online Purchasing Pilot, Kyle Jones

Theses and Dissertations--Economics

This dissertation consists of three chapters that evaluate how a change in the redemption of Supplemental Nutrition Assistance Program benefits impacted grocery purchasing behavior and food consumption to provide some of the first estimates of the impacts from the pilot. The SNAP Online Purchasing Pilot (OPP) allowed recipients to use their benefits online for participating retailers which was initially planned for 8 participating pilot states with a few participating retailers but massively expanded during the COVID-19 pandemic. The first two chapters evaluate how the SNAP OPP impacts grocery purchasing behavior with the first chapter evaluating before the COVID-19 pandemic and …

Essays On Impacts Of Natural Disasters, Fang-Yu Yeh

Theses and Dissertations--Economics

This dissertation consists of three chapters that study how natural disasters affect households and individuals. The first chapter examines how Kentucky’s housing market responds to changes in flood risk information. The second chapter looks at disproportionate drinking water non-compliance post-disaster. The third chapter studies the effect of flooding events and the national school meals program in Kentucky on education outcomes.

The first chapter examines Kentucky’s housing market response to changes in the Federal Emergency Management Agency’s (FEMA) flood maps and how the responses differ depending on whether an area has been flooded recently. I use Zillow’s ZTRAX property transaction data …

Modulating The Mtor Pathway Using Inducible Retrogradely Transported Aavs As A Novel Approach To Improve Motor Recovery In Spinal Cord Injury, Christopher Bosse-Joseph

Theses and Dissertations--Medical Sciences

Spinal cord injury poses multiple regeneration barriers, including neuronal-intrinsic and extrinsic factors. Overcoming these barriers has stood as a longstanding challenge in neuroscience. A well-studied mechanism to promote spinal cord regeneration and locomotor recovery is activating the PI3K/mTOR pathway by knocking out phosphatase and tensin homolog protein (PTEN). PTEN knockout (PTEN-KO) studies have traditionally used adeno-associated virus (AAV) viral vectors to improve functional recovery. The use of traditional AAV serotypes to induce PTEN-KO has shown promise to improve functional recovery in rodent models; however, these approaches show significant limitations for translational utility. Firstly, the use of traditional AAV serotypes to …

Effects Of Pancreatic Amylin On The Peripheral And Cns Immune Response In A Model Of Type-2 Diabetic Brain Injury, Edric Da'shon Winford

Theses and Dissertations--Neuroscience

Type-2 diabetes (T2D) is a metabolic disorder that increases the risk for cerebrovascular disease and dementia and is associated with the progression of Alzheimer's Disease; however, the mechanisms responsible for T2D-associated dementia are still poorly understood. T2D leads to alterations of the innate and adaptive immune response that contribute to its progression, but how these cells contribute to cognitive decline during T2D is unknown. As there are no approved therapeutics for T2D that modulate the immune response, it is important that we investigate how peripheral immune cells contribute to cognitive decline during T2D. Amylin is an amyloidogenic hormone synthesized and …

Contributions Of The Replication Initiator Protein Dnaa To Physiology And Virulence Of The Lyme Disease Spirochete, Andrew Krusenstjerna

Theses and Dissertations--Microbiology, Immunology, and Molecular Genetics

Borrelia burgdorferi, the etiological agent of Lyme disease, is the most prevalent vector-borne disease in the United States. The spirochetal population is naturally maintained by consistently cycling between Ixodid ticks and small vertebrates. To survive within these diverse niches, B. burgdorferi has evolved a unique physiology and regulatory network to sense and respond to environmental fluxes. Replication is a hallmark of the Lyme spirochete’s enzootic life cycle, specifically at the nymphal tick-to-vertebrate interface. The mechanisms and regulatory schema for the basic cellular processes in B. burgdorferi, or indeed any member of the phylum spirochaetota, are largely unknown. The central hypothesis …