Digital Commons Network^™

Tomato, Robert Yokel

Aluminum in Beverages and Foods: A Compilation

No abstract provided.

Honey, Robert Yokel

Aluminum in Beverages and Foods: A Compilation

No abstract provided.

Causes And Prevention Of Thermal Runaway In Lithium-Ion Batteries — A U.S. Utility Perspective, Shaun Lavin, Kwabena Kyeremeh, Elias Nemeh, David Beyerle, Chad Alkire, Samuel Kelty, Lakshmi Srinivasan, Stephanie Shaw, Erin Minear, Haresh Kamath, Dan Ionel, Aron Patrick

Power and Energy Institute of Kentucky Faculty Publications

Lithium-ion batteries are a critically important technology for maintaining grid reliability with the integration of variable intermittent renewable energy resources. However, lithium-ion batteries also pose significant human safety and infrastructure hazards due to the inherent risk of thermal runaway, fire, and explosion, which should be understood, mitigated, and managed. While battery manufacturers have primary responsibility for the design, manufacturing, and software which are necessary to keep battery storage systems safe, electric utilities also have an important role in understanding these risks and adopting best practices to mitigate them. This paper provides background on utility-scale battery deployment, an overview of a …

Economic Contribution Of Kentucky Airports, P. Gayle Marks, Bethany Paris, Bryan Gibson

Kentucky Transportation Center Research Report

Airports generate economic impacts that are felt well beyond their physical boundaries by supporting commerce, tourism, and the provision of essential services. To understand the economic contributions of airports throughout Kentucky, researchers collected data from general aviation (GA) airports and commercial service (CS) airports across the state on operational statistics, levels of employment, and usage patterns in calendar year 2022. IMPLAN^® econometric models were developed to estimate the economic contributions of the state’s airports. These models show that in 2022 Kentucky’s airports contributed $23.7 billion in total economic output, which equals 9.1 percent of its gross domestic product ($261.5 …

Spatiotemporal Wind Energy Assessment For Transmission Network Integration Considering The Location Of Electrical Substations And Loads, Kwabena Kyeremeh, Rosemary E. Alden, Aron Patrick, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Wind energy is an abundant renewable resource that can support decarbonization of energy supply. It is, therefore, essential to conduct a comprehensive assessment of wind energy potential for effective transmission network planning and integration. This work introduces a spatial-temporal assessment methodology for wind energy name plate-rated power capacity that considers the locations of electrical substations and transmission lines. This methodology applies Geographic Information System (GIS) land cover data to define siting exclusions for wind turbine installations. The correlation between generated wind power and estimates of power system load, as well as capacity factor, on a sub-regional basis for specific latest …

A Method For Teaching Biostatisticians To Write And Critique Specific Aims, Jesse D. Troy, Gregory P. Samsa, Megan L. Neely, Steven C. Grambow, Sarah Peskoe, Emily Slade, Gina Maria Pomann

Biostatistics Faculty Publications

This article describes the design of a single instructional module on writing and critiquing the Specific Aims (SA) section of a grant proposal for a biomedical research study. It begins by discussing the goals and learning objectives for the module. Then, it discusses the typical structure of a SA section to orient readers to the core content. This method is rooted in using an established framework for scientific writing, which is presented in brief, along with examples of how it applies to writing the SA section. Then, the structure of the instructional module is described, including the exercises for participants. …

Adverse Childhood Experiences And Psychological Correlates Of Substance Use Disorders Among Black Sexual Minority Women, Shemeka Thorpe, Kaylee A Palomino, Natalie Malone, Danelle Stevens-Watkins

Kinesiology and Health Promotion Faculty Publications

This study examined the influence of adverse childhood experiences (ACEs) on Black sexual minority women's mental health and substance use disorders in adulthood. Secondary data analysis was conducted using N = 149 Black sexual minority women's reports from the Generations Study. Study variables included psychological distress, chronic strains, stressful life events, ACEs, and substance use disorders, including alcohol use disorder and drug use disorder. Quantitative data analysis consisted of descriptives and bivariate correlations. Participants' total ACE scores were positively significantly correlated with increased alcohol misuse, chronic life strains, and stressful life events. Exposure to household interpersonal violence and household mental …

Storytelling As Assessment And Assessment As Storytelling: Reading And Writing Equity, Julene L. Jones, Mary K. Thompson, Co-Creating Action, Watermark

Library Presentations

Wrestling with both the language of storytelling and the language of narrative, this presentation repositions assessment work as creative and historical, giving a double responsibility to its authors. How we speak of education and how we use this information to improve it begs the questions of character and audience. In these questions is the larger consideration of equity. This presentation explores what storytelling as an art can teach us about the institutional stories we are telling.

Open Access In The Age Of Ai: The Journal Of Appalachian Health And Hurricane Helene Recovery, Noah Wren, Bradley Firchow

Journal of Appalachian Health

The recent destruction brought upon the Appalachian region by Hurricane Helene has emphasized the importance of the Journal of Appalachian Health. As an open-access peer-reviewed source of information, the Journal plays a critical role in not only facilitating public health research about Hurricane Helene, but also combating misinformation regarding the event. In the days following Hurricane Helene, misinformation about the federal government’s response, along AI generated images, have left many in the region confused and misled about what had happened. Going forward, the Journal will play an necessary part in making sure accurate information is shared to understand how …

Psychosocial Factors, Stress And Sleep Among Rural Appalachian Kentucky Residents With Type 2 Diabetes Mellitus, Blake Dipaola, Zoe Taylor, Eric Hennemann, Brittany L. Smalls, Philip M. Westgate, Nancy Schoenberg

Journal of Appalachian Health

Introduction: Rural Appalachian residents experience higher rates of most chronic diseases, including type 2 diabetes mellitus (T2DM). Stress and sleep deficiency also are common in the region.

Purpose: To better understand these associated health burdens, the relationship among these conditions and psychosocial factors—such as depressive symptoms, distress, empowerment, and social support—was examined among Appalachian residents with T2DM.

Methods: Using data collected from a community-based sample of Appalachian adults with T2DM, the study examined whether psychosocial factors were associated with perceived stress (Cohen Perceived Stress Scale) and self-reported sleep deficiency (Epworth Sleepiness Scale). Multilevel linear mixed effects regression modeling was used …

Accurate Synthesis Of Dysarthric Speech For Asr Data Augmentation, Mohammad Soleymanpour, Michael T. Johnson, Rahim Soleymanpour, Jeffrey Berry

Electrical and Computer Engineering Faculty Publications

Dysarthria is a motor speech disorder often characterized by reduced speech intelligibility through slow, uncoordinated control of speech production muscles. Automatic Speech recognition (ASR) systems can help dysarthric talkers communicate more effectively. However, robust dysarthria-specific ASR requires a significant amount of training speech, which is not readily available for dysarthric talkers. This paper presents a new dysarthric speech synthesis method for the purpose of ASR training data augmentation. Differences in prosodic and acoustic characteristics of dysarthric spontaneous speech at varying severity levels are important components for dysarthric speech modeling, synthesis, and augmentation. For dysarthric speech synthesis, a modified neural multi-talker …

The Alzmatch Pilot Study - Feasibility Of Remote Blood Collection Of Plasma Biomarkers For Preclinical Alzheimer’S Disease Trials, S. Walter, O. Langford, G. A. Jimenez-Maggiora, S. Abdel-Latif, R. A. Rissman, J. D. Grill, J. Karlawish, A. Atri, S. Bruschi, K. Hussen, M. C. Donohue, G. A. Marshall, Gregory Jicha, M. Racke, R. S. Turner, C. H. Van Dyck, V. Venkatesh, K. E. Yarasheski, R. Sperling, J. Cummings, Paul Aisen, R. Raman

Neurology Faculty Publications

BACKGROUND: Advances in plasma biomarkers to detect Alzheimer’s disease (AD) biology allows researchers to improve the efficiency of participant recruitment into preclinical trials. Recently, protein levels of plasma amyloid-beta and tau proteins have been shown to be predictive of elevated amyloid in brain. Online registries, such as the Alzheimer’s Prevention Trials (APT) Webstudy, include and follow participants using remote assessments to facilitate efficient screening and enrollment of large numbers of individuals who may be at higher risk for AD.

OBJECTIVES: The AlzMatch Pilot Study investigated the feasibility of recruiting individuals from an online registry for blood sample collection at community-based …

Solar Pv And Ev Controls For Reactive Power Support On Large Distribution Systems Modeled With Experimental And Synthetic Loads, Rosemary E. Alden, Malcolm Mcculloch, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

Changes to electric power distribution equipment may be needed to adapt to distributed energy resources (DERs) such as solar photovoltaic (PV) generation and electric vehicle (EV) batteries. Within this paper, an optimization methodology for reactive power support (RPS) controls managed by utilities for EV bi-directional charger power factor and improve substation power quality and voltage across the system is proposed. An IEEE benchmark distribution system, the 123 node test feeder, is modified to include 1,765 experimental residential profiles at typical, high resolution of 15min from smart meters, solar PV generation calculated from weather data, and EV modules based on driver …

Parallel Electrophysiological Abnormalities Due To Covid-19 Infection And To Alzheimer’S Disease And Related Dementia, Yang Jiang, Jennifer Neal, Pradoldej Sompol, Görsev Yener, Xianghong Arakaki, Christopher M. Norris, Francesca R. Farina, Agustin Ibanez, Susanna Lopez, Abdulhakim Al-Ezzi, Voyko Kavcic, Bahar Güntekin, Claudio Babiloni, Mihály Hajós

Neurology Faculty Publications

Many coronavirus disease 2019 (COVID-19) positive individuals exhibit abnormal electroencephalographic (EEG) activity reflecting “brain fog” and mild cognitive impairments even months after the acute phase of infection. Resting-state EEG abnormalities include EEG slowing (reduced alpha rhythm; increased slow waves) and epileptiform activity. An expert panel conducted a systematic review to present compelling evidence that cognitive deficits due to COVID-19 and to Alzheimer’s disease and related dementia (ADRD) are driven by overlapping pathologies and neurophysiological abnormalities. EEG abnormalities seen in COVID-19 patients resemble those observed in early stages of neurodegenerative diseases, particularly ADRD. It is proposed that similar EEG abnormalities in …

The Undergraduate Engineering Mental Health Help-Seeking Instrument (Ue-Mh-Hsi): Development And Validity Evidence, Joseph H. Hammer, Courtney J. Wright, Melanie E. Miller, Sarah A. Wilson

Chemical and Materials Engineering Faculty Publications

Background: Undergraduate engineering students experiencing distress are less likely than peers to ask for professional help. A population-specific instrument to facilitate the identification of factors that influence mental healthcare utilization could guide development and testing of interventions to increase help seeking.

Purpose: We used mixed methods guided by the Integrated Behavioral Model (IBM) to develop and evaluate the Undergraduate Engineering Mental Health Help-Seeking Instrument (UE-MH-HSI).

Method: First, we adapted existing measures of mental health help-seeking intention and mechanisms (i.e., attitudes, perceived norm: injunctive, perceived norm: descriptive, personal agency: autonomy, personal agency: capacity). Second, we coded qualitative interviews (N = 33) …

Communities That Heal Intervention And Mortality Including Polysubstance Overdose Deaths: A Randomized Clinical Trial, Bridget Freisthler, Rouba A. Chahine, Jennifer Villani, Redonna Chandler, Daniel J. Feaster, Svetla Slavova, Jolene Defiore-Hyrmer, Alexander Y. Walley, Sarah Kosakowski, Arnie Aldridge, Carolina Barbosa, Sabana Bhatta, Candace Brancato, Carly Bridden, Mia Christopher, Tom Clarke, James David, Lauren D'Costa, Irene Ewing, Soledad Fernandez, Erin Gibson, Louisa Gilbert, Megan E. Hall, Sarah Hargrove, Timothy Hunt, Elizabeth N. Kinnard, Lauren Larochelle, Aaron Macoubray, Shawn R. Nigam, Edward V. Nunes, Carrie B. Oser, Sharon Pagnano, Peter J. Rock, Pamela Salsberry, Aimee Shadwick, Thomas J. Stopka, Sylvia Tan, Jessica L. Taylor, Philip M. Westgate, Elwin Wu, Gary A. Zarkin, Sharon L. Walsh, Nabila El-Bassel, T. John Winhusen, Jeffrey H. Samet, Emmanuel A. Oga

Biostatistics Faculty Publications

IMPORTANCE: The HEALing Communities Study (HCS) evaluated the effectiveness of the Communities That HEAL (CTH) intervention in preventing fatal overdoses amidst the US opioid epidemic.

OBJECTIVE: To evaluate the impact of the CTH intervention on total drug overdose deaths and overdose deaths involving combinations of opioids with psychostimulants or benzodiazepines.

DESIGN, SETTING, AND PARTICIPANTS: This randomized clinical trial was a parallel-arm, multisite, community-randomized, open, and waitlisted controlled comparison trial of communities in 4 US states between 2020 and 2023. Eligible communities were those reporting high opioid overdose fatality rates in Kentucky, Massachusetts, New York, and Ohio. Covariate constrained randomization stratified …

Upregulation Of Fatty Acid Synthase Increases Activity Of Β-Catenin And Expression Of Notum To Enhance Stem-Like Properties Of Colorectal Cancer Cells, Courtney O. Kelson, Josiane Weber Tessmann, Mariah E. Geisen, Daheng He, Chi Wang, Tianyan Gao, B. Mark Evers, Yekaterina Y. Zaytseva

Markey Cancer Center Faculty Publications

Dysregulated fatty acid metabolism is an attractive therapeutic target for colorectal cancer (CRC). We previously reported that fatty acid synthase (FASN), a key enzyme of de novo synthesis, promotes the initiation and progression of CRC. However, the mechanisms of how upregulation of FASN promotes the initiation and progression of CRC are not completely understood. Here, using Apc/VillinCre and ApcMin mouse models, we show that upregulation of FASN is associated with an increase in activity of β-catenin and expression of multiple stem cell markers, including Notum. Genetic and pharmacological downregulation of FASN in mouse adenoma organoids decreases the activation of β-catenin …

2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute

Kentucky Water Resources Annual Symposium

The program and proceedings contains details of the 2024 Kentucky Water Resources Symposium, including presentations, award winners, and poster presentations.

This symposium was planned and conducted as a part of the state water resources research institute annual program that is supported by Grant/Cooperative Agreement Number G21AP10631-02 from the United States Geological Survey (USGS). The contents of this proceedings document and the views and conclusions presented at the symposium are solely the responsibility of the individual authors and presenters and do not represent the official views of the USGS or of the symposium organizers and sponsors. This publication is produced with …

2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute

Kentucky Water Resources Annual Symposium

No abstract provided.

Public Librarians' Roles In Natural Disasters: Stories Of Leadership And Resilience, Denise Lyons, April Hobbs, Feili Tu-Keefner, Denise Gomez, Marcia A. Mardis

Library Research Seminar 8: Telling Library Stories

No abstract provided.

Sharing The Story Of Public Library Programming For Young Children With Disabilities Or Developmental Delays, Denice Adkins, Maria Cahill, Alicia Long, Bobbie Sartin Long, Derek Daskalakes

Library Research Seminar 8: Telling Library Stories

No abstract provided.

An Introduction To Infophilia, A Positive Psychology Of Information, Anita S. Coleman

Library Research Seminar 8: Telling Library Stories

This paper will tell some of the stories of infophilia, a positive psychology of information, avant-garde research. The goal of Brenda Dervin’s ground-breaking research was not just to develop the sense-making theory, framework, and tools, but also to “invent communication alternatives and assess their utility.” One of the ‘practice communication inventions’ of Brenda Dervin was the ‘Good news newsletter’ where she developed infosheets for doctors, schools, and medical clinics (Neill, 1992, p. 6). I am no Brenda Dervin. But I am a strongly interdisciplinary scholar who has been a tenured librarian, LIS school faculty, library director, publisher for the voiceless, …

Beyond The Numbers: Capturing Impactful Patron Interactions In Library Data, Jenica Ibarra, Triveni Kuchi, Julie Still

Library Research Seminar 8: Telling Library Stories

No abstract provided.

Stories From The Road: Embedding A Librarian With An Immersive Leadership Development Travel Experience, Eric Tans

Library Research Seminar 8: Telling Library Stories

No abstract provided.

Lessons Learned From Developing Dashboards To Support Decision-Making For Community Opioid Response By Community Stakeholders: Mixed Methods And Multisite Study., Naleef Fareed, Ramona G. Olvera, Yiting Wang, Michael Hayes, Elizabeth Liz Larimore, Peter Balvanz, Ronald Langley, Corinna A. Noel, Peter J. Rock, Daniel Redmond, Jessica Neufeld, Sarah Kosakowski, Daniel R. Harris, Marc Larochelle, Timothy R. Huerta, Lashawn Glasgow, Emmanuel Oga, Jennifer Villani, Elwin Wu

Center on Drug and Alcohol Research Faculty Publications

BACKGROUND: Data dashboards are published tools that present visualizations; they are increasingly used to display data about behavioral health, social determinants of health, and chronic and infectious disease risks to inform or support public health endeavors. Dashboards can be an evidence-based approach used by communities to influence decision-making in health care for specific populations. Despite widespread use, evidence on how to best design and use dashboards in the public health realm is limited. There is also a notable dearth of studies that examine and document the complexity and heterogeneity of dashboards in community settings.

OBJECTIVE: Community stakeholders engaged in the …

Planetary Health Learning Objectives: Foundational Knowledge For Global Health Education In An Era Of Climate Change, Kathryn H. Jacobsen, Caryl E. Waggett, Pamela Berenbaum, Brett R. Bayles, Gail L. Carlson, René English, Carlos A Faerron Guzmán, Meredith L. Gartin, Liz Grant, Thomas L. Henshaw, Lora L. Iannotti, Philip J. Landrigan, Nina Lansbury, Hao Li, Maureen Y. Lichtveld, Ketrell Mcwhorter, Jessica E. Rettig, Cecilia J. Sorensen, Eric J. Wetzel, Dawn Michele Whitehead, Peter J. Winch, Keith Martin

Earth and Environmental Sciences Faculty Publications

Planetary health is an emerging field that emphasises that humans depend on a healthy Earth for survival and, conversely, that the sustainability of Earth systems is dependent on human behaviours. In response to member demands for resources to support teaching and learning related to planetary health, the Consortium of Universities for Global Health (CUGH) convened a working group to develop a set of planetary health learning objectives (PHLOs) that would complement the existing ten CUGH global health learning objectives. The eight PHLOs feature Earth system changes, planetary boundaries, and climate change science; ecological systems and One Health; human health outcomes; …

China In Global Digital Trade Governance: Towards A Development-Oriented Agenda?, Yujia He, Ka Zeng

Patterson School of Diplomacy and International Commerce Faculty Publications

Existing literature on the behaviour of rising powers in global trade governance has yielded inconclusive evidence about their role and impact. This article contributes to this literature by examining China's role in global digital trade governance, an issue area which so far has not received sufficient scholarly attention. Specifically, it addresses the following question: as a self-proclaimed leader of the developing world in digital development, to what extent do its preferences and negotiation approach align with the interests of other developing countries? Analysing China's participation in three sets of negotiations using process tracing, the article argues that China's dual identity …

The Seattle Amyotrophic Lateral Sclerosis (Als) Patient Project Database: Observational, Longitudinal, Dyadic Characterization Of People With Als And Their Partners, Suzanne C. Segerstrom, Edward J. Kasarskis

Neurology Faculty Publications

Introduction: The median survival time in ALS is approximately 3 years, but survival times range from less than a year to more than 10 years and much variance in disease course remains to be explained. As is true for physical outcomes, there is considerable variance in QOL, which is influenced by psychological health, coping, and social support, among other psychosocial factors. The Seattle ALS Patient Project Database (SALSPPD) provides a unique opportunity for researchers to address established and novel hypotheses about disease progression and QOL in ALS.

Methods: The SALSPPD is a longitudinal dataset of people with ALS (n = …

Regenerating Family Member 3 Alpha Is Predictive Of Mortality Following Emergent Large Vessel Occlusion, Madison Sands, Christopher J. Mclouth, Jacqueline A. Frank, Benton Maglinger, Nathan Millson, Mais N. Al-Kawaz, Shivani Pahwa, David L. Dornbos, Douglas E. Lukins, Amanda L. Trout, Ann M. Stowe, Justin F. Fraser, Keith R. Pennypacker

Biostatistics Faculty Publications

Regenerating Family Member 3 Alpha (REG3A) is an antimicrobial protein secreted by the intestine and pancreas with additional immunomodulatory properties. Previously, we published that REG3A expression in ischemic stroke patient systemic blood, during mechanical thrombectomy (MT), is significantly associated with inflammatory cytokines and patient function on admission. This paper, however, did not investigate post-acute death rates. Therefore, we investigated plasma REG3A protein expression, during MT, in patients (n = 141) that survived or died within the end of the follow-up after MT. Subjects who died had significantly higher systemic plasma REG3A levels at the time of MT compared to survivors …

Investigating Effectiveness Of Inverted Classroom In Undergraduate Statistics Education, Xin Ma, Jing Zhang, Petya Karkelanova, Michael C. Osborne, Anushka Karkelanova

Educational, School, and Counseling Psychology Faculty Publications

Data collected from an educational experiment were analyzed to investigate the effectiveness of an instructional reform referred to as the inverted classroom (learning activities traditionally taking place inside the classroom now take place outside the classroom and vice versa) in undergraduate statistics education. Students were taught the same statistics course in the inverted classroom (135 students) and the traditional classroom (135 students) over one semester. A small sample HLM (hierarchical linear modeling) approach was used to account for the data structure of students nested within 12 sections of the course and small sample sizes at both student and section levels. …