Digital Commons Network^™

An Analysis And Conductor's Guide To Allen Webber'sThree American Poets, John Wayne Weatherspoon

Theses and Dissertations--Music

Allen Webber’s Three American Poets is a three-movement choral work based on texts by several American poets. This monograph shines light on the compositional style of Webber by means of an in-depth score analysis of this work. Webber’s experience as a written theory and aural skills professor informs his writing style. Frequent correspondence and interviews with the composer informed the study through qualitative data. Though the piece is accessible to advanced high school choruses and beyond, it will at times challenge those choirs with unexpected chromatic movements. This study provides conductors with a guide to develop a creative and scholarly …

Beyond The Score: Interdisciplinary Connections In The High School Choral Ensemble, Kellie Clark

Theses and Dissertations--Music

An interest in interdisciplinary instruction, generally and within the arts, can be traced through numerous progressive educational movements extending back to the earliest philosophers. There has, however, been limited discussion regarding an interdisciplinary approach in high school ensemble classrooms. If a holistic teaching approach, one which examines a musical work from multiple angles while inviting and encouraging student curiosity and agency, can benefit music students in profound ways, why are secondary choral educators hesitant to employ such methods?

This monograph presents a concrete and practical application for the inclusion of interdisciplinary instruction in the high school choral classroom developed through …

Dimitris Kafyris: The Legacy And Pedagogy Of A Trailblazing Greek Trumpeter, Stephen M. Wadsack

Theses and Dissertations--Music

Dimitris Kafyris (Δημήτρης Κάφυρης, 1932–2020) is regarded as one of the most talented trumpeters of the twentieth century, within his native homeland of Greece. From the early 1950s into the mid-1980s, Kafyris performed with the Athens State Orchestra (Greece’s premier orchestral ensemble), the Greek Radio Symphony, and the National Opera. During this period, Kafyris also maintained a teaching position at the Hellenikon Conservatory (Ελληνικόν Ωδείον) in Athens. Following what many would already consider to be a robust career, Kafyris returned home to the Greek island of Corfu, where he assumed the roles of Bandmaster and Director of the Corfu Philharmonic …

Exploring How Music Therapy Can Support Transition-Aged Young Adults With Intellectual And Developmental Disabilities: An Adapted Multiple Case Study, Hayley Davis

Theses and Dissertations--Music

Young adults with Intellectual and Developmental Disabilities (IDD) face barriers and challenges after their transition from high school to their post-high school lives. While in high school, a student with IDD receives support and services through the Individuals with Disabilities Education Act, but once a student with IDD graduates high school, they no longer have access to the services that they were once receiving. While this phenomenon (often referred to as the “disability cliff”) has been examined, there is a lack of research surrounding the perspectives and lived experiences of young adults with IDD. Furthermore, there is very limited research …

Humor Matters: An Adapted Multiple Case Study Exploring Music Therapists’ Perspectives Of Humor With Older Adults, Caleb M. Posey

Theses and Dissertations--Music

Humor is a ubiquitous human experience and a skill retained in older adulthood. It is also an integral but elusive therapeutic tool with numerous benefits and risks to well-being. Therapeutic humor – the application of humor to client well-being – is an emerging area of study. However, scant music therapy literature on humor is available. The purpose of this qualitative thesis was to explore the use and function of humor in music therapy with older adults from the perspectives of experienced music therapists. There were three research questions: (1) how do music therapists describe their use of humor with older …

Understanding The Effects Of Hormone Treatments On The Transgender Singer: A Pedagogical Study And Voice Studio Guide, Erin M. Hannon

Theses and Dissertations--Music

Transitioning from one gender to another can be an arduous and emotionally charged experience, accompanied by many physical and mental transformations. The journey of self-discovery and vocal explorations is both unique and deeply personal. Modifications that emerge in an individual's vocal characteristics have a profound influence on their capacity to communicate and express themselves.

Transgender vocal students and professional singers must navigate the delicate balance between their vocal and gender identities while considering the possible risks of Gender Affirming Hormone Therapy. Though these therapies may significantly alter one's appearance and overall well-being, they are also capable of causing notable declines …

Honk!: Meaning And Activism In 21st Century American Street Bands, Isaac Maupin

Theses and Dissertations--Music

In this dissertation, I explore activism, music, and meaning through the lens of HONK! Bands in the United States. HONK! A Festival of Activist Street Bands began in Sommerville, Massachusetts, in 2006. Since its inception, the festivals have grown on a national and global scale. The festivals, however, operate as a convenient organizing structure for the bands themselves and are not a primary focus of this work. Instead, I examine activism, learning, and value as systems within the HONK! culture (each topic with a devoted chapter) to, through a phenomenological lens, better understand how HONK! bands fit within American culture. …

Formative Musical Experiences Of Older Adult Sexual Minority Women From Rural Areas: An Adapted Case Study, Sabrina Hartsfield

Theses and Dissertations--Music

People often have strong emotional connections between music and memories, which can affect a person’s identity and self-concept. The deep meaning that individuals find within music that is important to them helps music therapists to make connections to clients and to work with clients to understand their experiences through the lens of music. The purpose of this project was to examine in depth the musical experiences of sexual minority women aged 65 and older from rural areas, and to see how musical experiences may have impacted their identity. In this adapted case study, I conducted in-depth one-on-one interviews and constructed …

How Spirituals Influenced Both Resistance To Nazis And Civil Rights Protests, Chandi Plummer

Theses and Dissertations--Music

How have American Negro Spirituals inspired later generations of oppressed and marginalized people? Which songs of suffering and hope were particularly poignant in providing courage and inspiration? Questions such as these sparked my research journey, reaching a crescendo during a lecture recital on November 10, 2023, and now culminating in a dissertation.

Spirituals inspired Albert Franklin Fisher and Dietrich Bonhoeffer in New York City in 1930 during the Harlem Renaissance and traveled (via phonograph and music books) with Bonhoeffer to Nazi Germany during World War II. In America, spirituals influenced Myles and Zilphia Horton, Rosa Parks, and Martin Luther King, …

Expert Perceptions Of Needs Of Pregnant Individuals With Substance Use Disorder In Kentucky: A Qualitative Multiple Case Study, Emma Foret Latham

Theses and Dissertations--Music

Substance misuse is a pandemic with far reaching effects on those personally affected, their families, and their communities. Kentucky has one of the highest rates of substance use disorder (SUD) in the country, and most research has focused on how to help men in recovery. There is very little research regarding how to support pregnant individuals with SUD. The purpose of this qualitative thesis was to identify the perceived needs of pregnant individuals with SUD, define characteristics of effective care, and learn how music therapists can support this population in substance use rehabilitation settings from the perspectives of experienced professionals. …

Ecuadorian Vocal Anthology In Four Rhythms, Wagner Mauricio Pástor Pazmiño Dr.

Theses and Dissertations--Music

Ecuador is a pluricultural and multilingual territory with four natural regions, several musical genres, and interpretations. Amazon, Galápagos, Mountain Range, and Coastal region. In the following dissertation, the author develops concepts of four traditional rhythms, their composers, and harmonic and phonetic characteristics from the mountain range region of his homeland, Ecuador.

The present document is a descriptive study of vocal Andean music and the application of the operatic style in classical vocal technique for performance practice.

The dissertation will support a lecture recital to fulfill the doctoral program's requirement in voice performance from the University of Kentucky.

Conceptual Blending: A Singer’S Analysis Of Libby Larsen’S Try Me, Good King: Last Words Of The Wives Of Henry Viii And A Conversation With The Composer, Kelsey Paige Ann Loeslie

Theses and Dissertations--Music

American composer Libby Larsen is celebrated for her versatility and expertise in crafting intricate text-music relationships, notably exemplified in her song cycle Try Me Good King: Last Words of the Wives of Henry VIII. This research explores Larsen's innovative compositional techniques in this cycle using Cross-Domain Mapping and Conceptual Blending Theory. Drawing from Lawrence Zbikowski's work, the study employs Conceptual Integration Networks to analyze Larsen's music, revealing the intricate interplay between text and music. By synthesizing these methodologies, the research comprehensively examines Larsen's song cycle, enhancing our understanding of her composition both from a music theory perspective and from a …

The Mechanism Of Sperm (Pro)Nuclear Migration In Plants And Animals, Yilin Zhang, Tomokazu Kawashima

Plant and Soil Sciences Faculty Publications

Gamete nuclear migration is a critical process during fertilization in flowering plants, yet its molecular mechanisms remain poorly understood. Recent studies have highlighted the essential role of cytoskeletal elements, particularly F-actin, in directing sperm nuclear migration, contrasting with the microtubule-driven migration in animals. We summarize the process of sperm nuclear migration in plants and the involvement of Class XI myosin XI-G in Arabidopsis, along with the ROP8-SCAR2 pathway’s ARP2/3-independent mechanism for F-actin nucleation. We also provide a comparative overview of examples from sea urchins, C. elegans, mice and yeast contrasting these mechanisms with those in plants. Finally, we …

Welcome To The Fruit Farm: How Queer Farmers Are Shaping The Agroecology Of The Future, Alessandra Del Brocco

Theses and Dissertations--Sociology

The question of sustainability has many different facets, but one of the most urgent issues is that of sustainable agriculture. Decades of agricultural policy demanded farmers go big or get out, more colloquially known as the government directive of the 20^th century to farm “fencerow to fencerow”. In the 21^st century, we now face a near-critical consolidation of farmland and decline in the overall number of farmers. If sustainability calls for a resilient, diversified agrisystem, how can we change direction at this point in the trajectory?

In this study, I demonstrate how queer farmers make valuable contributions to …

A Gis Tool For Optimal Forage Species Selection, David B. Hannaway, Christopher Daly, Michael D. Halbleib, Linda Brewer, Sophie Baur, Chelsea Clark, Emilie Krecklow, Scott Bassett

IGC Proceedings (1977-2023)

To determine appropriate forage species for US ecoregions, geographic information technologies (GIS) are being used to create climatic and soil factor maps. Excel spreadsheets and RStudio are used to create response functions of forage species to minimum and maximum temperature, annual precipitation, soil pH, soil salinity, and salinity. National forage data and expert opinion will evaluate quantitative tolerances, seasonal yield profiles, and pollinator suitability. These maps and agronomic and livestock use information will be shared with forage specialists and farmers to provide alternatives for improved perenniality, increased diversity, and system circularity. Future work will include development and evaluation of climate …

Navigating Asynchronous Online Learning: The Impacts Of Active Learning And Assigned Group Work On Student Motivation, Belonging, And Inclusion, Shea Elisabeth Carr

Theses and Dissertations--Biology

Motivation, belonging, and inclusion are all critical factors for student success but can be difficult to support in asynchronous online courses. Active learning and required group work have been shown to increase student motivation in in-person and synchronous online courses, but little is known about their impact in online asynchronous settings. This dissertation aimed to 1) evaluate the effect of active learning on student motivation in an online asynchronous setting and 2) evaluate the impact of assigned group work on student motivation and perceptions of belonging and inclusion within the context of an online, asynchronous physiology laboratory course. It was …

Elucidating The Effect Of Jak/Stat Signaling On Initiation Of Individualization, Sepideh Dadkhah

Theses and Dissertations--Biology

The JAK/STAT pathway is renowned for its involvement in diverse cellular processes, yet its precise role in the later events of spermiogenesis needs to be clarified. Spermiogenesis unfolds in the testis, where synchronized spermatid development occurs within two somatic cyst cells before being released into the seminal vesicle. Prior to this release, spermatid bundles undergo individualization, where F-actin investment cones accumulate at the nuclei of elongated spermatids and move down the length of the interconnected cysts, stripping away excess organelles and cytoplasm, resulting in individual spermatids that are then coiled and released into the testis lumen. Individualization depends on JAK/STAT …

Co-Divergence Of Lemur Hosts And Gut Microbiomes Across Multiple Evolutionary Scales, Mariah E. Donohue

Theses and Dissertations--Biology

This dissertation bridges micro- and macroevolutionary approaches to understand the co-diversification of animal hosts and their gut microbiomes at different evolutionary timescales. I examined these dynamics using wild lemurs, a diverse Primate clade endemic to the island of Madagascar.

First, I tested the relative effects of host phylogenetic relationships, diet, and habitat in shaping the gut microbiome through deep evolutionary time and across distinct microbial kingdoms. I designed a natural experiment sampling feces from rainforest and dry forest lemur communities with similar phylogenetic assemblages and considerable variation in dietary strategy. Then, I amplified and sequenced two metabarcoding genes, the V4 …

Abnormal Regulation Of Mitochondrial Sphingolipids During Aging And Alzheimer’S Disease, Simone M. Crivelli, Zainuddin Quadri, Ahmed Elsherbini, Hemendra J. Vekaria, Patrick G. Sullivan, Wenbo Zhi, Pilar Martinez-Martinez, Stefka D. Spassieva, Erhard Bieberich

Markey Cancer Center Faculty Publications

During pathogenesis of Alzheimer’s disease (AD), mitochondria suffer alterations that lead to low energy production and reactive oxygen species formation. However, the mechanism of impaired mitochondria homeostasis in AD is not fully understood. We hypothesized that abnormal sphingolipid metabolism in mitochondria could be one of the contributing factors to mitochondrial dysfunction. Synaptic and non-synaptic mitochondria were isolated from 5xFAD and wild type (WT) mice at 3 and 7 months using Ficoll gradient ultracentrifugation, and their function was analyzed using Seahorse assay. Additionally, mitochondria were ana- lyzed using mass spectrometry for proteomics and sphingolipidomics analyses. Sphingolipid levels were also determined in …

Mechanisms Of Γδ T Cell Accumulation In Visceral Adipose Tissue With Aging, Sujata Mukherjee, Maria E. C. Bruno, Jason Oakes, Gregory S. Hawk, Arnold Stromberg, Donald A. Cohen, Marlene E. Starr

Markey Cancer Center Faculty Publications

γδ T cells are resident in visceral adipose tissue (VAT) where they show an age- associated increase in numbers and contribute to local and systemic chronic inflammation. However, regulation of this population and mechanisms for the age-dependent accumulation are not known. In this study, we identified a progressive trend of γδ T cell accumulation in VAT over the lifespan in mice and explored physiological mechanisms contributing to accumulation. Using isochronic parabiotic pairs of wild-type (WT) and T cell receptor delta knockout (TCRδ KO) mice at young and old age, we confirmed that VAT γδ T cells are predominately a tissue-resident …

Pai-1 As A Critical Factor In The Resolution Of Sepsis And Acute Kidney Injury In Old Age, Maria E. C. Bruno, Sujata Mukherjee, Jamie L. Sturgill, Virgilius Cornea, Peng Yeh, Gregory S. Hawk, Hiroshi Saito, Marlene E. Starr

Markey Cancer Center Faculty Publications

Elevated plasma levels of plasminogen activator inhibitor type 1 (PAI-1) are documented in patients with sepsis and levels positively correlate with disease severity and mortality. Our prior work demonstrated that PAI-1 in plasma is positively associated with acute kidney injury (AKI) in septic patients and mice. The objective of this study was to determine if PAI-1 is causally related to AKI and worse sepsis outcomes using a clinically-relevant and age-appropriate murine model of sepsis. Sepsis was induced by cecal slurry (CS)-injection to wild-type (WT, C57BL/6) and PAI-1 knockout (KO) mice at young (5–9 months) and old (18–22 months) age. Survival …

A Community-Engaged, Mixed-Methods Approach To Prioritizing Needs In A Statewide Assessment Of Community Cancer Needs, Jessica R. Thompson, Todd Burus, Caree R. Mcafee, Christine Stroebel, Madeline Brown, Keeghan Francis, Melinda Rogers, Jennifer Redmond Knight, Elaine Russell, Connie L. Sorrell, Elizabeth A. Westbrook, Pamela C. Hull

Markey Cancer Center Faculty Publications

Introduction Kentucky has the highest all-site cancer incidence and death rate in the US. In 2021, the University of Kentucky Markey Cancer Center convened a steering committee to conduct a statewide community cancer needs assessment (CNA). The goal of the final CNA phase was to gather community input on prioritizing Kentucky’s cancer-related needs and ways to address them. Methods In 2021, we recruited 162 people to participate in online concept mapping, a participatory mixed method, to explore connections and identify priority areas. Fifty-one community members and 111 organizational partners participated in survey-based activities to prioritize 80 items representing key CNA …

Population-Level Incidence Of Human Papillomavirus–Positive Oropharyngeal, Cervical, And Anal Cancers, By Smoking Status, Sameer V. Gopalani, Mona Saraiya, Bin Huang, Thomas Tucker, Jacqueline M. Mix, Anil K. Chaturvedi

Markey Cancer Center Faculty Publications

We estimated the population-level incidence of human papillomavirus (HPV)–positive oropharyngeal, cervical, and anal cancers by smoking status. We combined HPV DNA genotyping data from the Centers for Disease Control and Prevention’s Cancer Registry Sentinel Surveillance System with data from the Kentucky Cancer Registry and Behavioral Risk Factor Surveillance System across smoking status. During 2004-2005 and 2014-2015 in Kentucky, most cases of oropharyngeal (63.3%), anal (59.7%), and cervical (54.9%) cancer were among individuals who ever smoked. The population-level incidence rate was higher among individuals who ever smoked than among those who never smoked for HPV-positive oropharyngeal (7.8 vs 2.1; adjusted incidence …

Neurotensin Accelerates Atherosclerosis And Increases Circulating Levels Of Short-Chain And Saturated Triglycerides, Jing Li, Liping Yang, Jun Song, Baoxiang Yan, Andrew J. Morris, Hunter Moseley, Robert M. Flight, Chi Wang, Jinpeng Liu, Heidi L. Weiss, Edward F. Morris, Ilyes Abdelhamid, Mathias J. Gerl, Olle Melander, Susan Smyth, B. Mark Evers

Markey Cancer Center Faculty Publications

Background and aims: Obesity and type 2 diabetes are significant risk factors for atherosclerotic cardiovascular disease (CVD) worldwide, but the underlying pathophysiological links are poorly understood. Neurotensin (NT), a 13-amino-acid hormone peptide, facilitates intestinal fat absorption and contributes to obesity in mice fed a high-fat diet. Elevated levels of pro-NT (a stable NT precursor produced in equimolar amounts relative to NT) are associated with obesity, type 2 diabetes, and CVD in humans. Whether NT is a causative factor in CVD is unknown.

Methods: Nt+/+ and Nt–/– mice were either injected with adeno-associated virus encoding PCSK9 mutants or crossed with Ldlr–/– …