Digital Commons Network^™

Methods And Compositions For Treating Neurological Disorders, Tae H. Ji, Inhae Ji

Chemistry Faculty Patents

This disclosure relates to methods and compositions useful for the treatment of senile dementia. More particularly the disclosure relates to methods and compositions for the treatment of senile dementia related to diabetes.

Transfected Mosquito Vectors, Stephen L. Dobson

Entomology Faculty Patents

A method is provided for producing an artificial infection in a Culicidae (mosquito) species. The mosquitoes include species within the subfamilies Culicinae and Anophelinae, and the species include Aedes albopictus, Aedes aegypti and Aedes polynesiensis infected with a Wolbachia infection. The infection may be a strain of Wolbachia which does not normally or naturally infect the selected mosquito species. The artificially infected Aedes mosquito can be introduced into a mosquito population to control the reproduction capability of the population by introducing an incompatible Wolbachia infection. The present method can be used as a novel means to limit mosquito-borne pathogens and …

Comparative Analysis Of Rural And Urban Start-Up Entrepreneurs, Hyunjeong Joo

Theses and Dissertations--Agricultural Economics

This study investigates the reasons for apparent differences in entrepreneurship rates in rural and urban areas using a Survey of Rural Kentucky Residents (SRKR) and the Panel Study of Entrepreneurial Dynamics (PSED) data. We estimate the determinants of dissimilar characteristics for rural and urban areas in two aspects: one is individual and contextual resources; the other is cultural tendencies of resources.

The results of the analysis suggest that the difference in available individual, economic, and social support resources does not explain the observed difference in entrepreneurship rate. The results also indicate that gender, ethnicity, income, and number of children in …

Finding Access To The Federal Courts: How The Inconsistent Application Of Federal Jurisdiction In Cases With Significant Foreign Relations Implications Affects Mining And Agriculture Industries, Rebecca C. Griffin

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Seeds Of Compromise: A Proposal And Justification For The Partial Deregulation Of Genetically Modified Alfalfa And Sugar Beets, Whitney J. Waters

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Animal Models For Periodontal Disease, Helieh S. Oz, David A. Puleo

Center for Oral Health Research Faculty Publications

Animal models and cell cultures have contributed new knowledge in biological sciences, including periodontology. Although cultured cells can be used to study physiological processes that occur during the pathogenesis of periodontitis, the complex host response fundamentally responsible for this disease cannot be reproduced in vitro. Among the animal kingdom, rodents, rabbits, pigs, dogs, and nonhuman primates have been used to model human periodontitis, each with advantages and disadvantages. Periodontitis commonly has been induced by placing a bacterial plaque retentive ligature in the gingival sulcus around the molar teeth. In addition, alveolar bone loss has been induced by inoculation or …

Forage News [2011-01], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Forages at KCA
• Small Ruminant Grazing Conference
• Mid-South Stocker Conference
• Kentucky's Agricultural Economy
• Forage Variety Test Results
• Regional Grazing Conference Coming to Louisville - Register Now!
• Alfalfa - Tall Fescue Row Orientation / Compatibility Comparisons on Establishment and Persistence Under Grazing
• Why Graze

Characterization Of Viral And Host Proteins And Rna Elements In Tombusvirus Replication, Kunj Bihari Pathak

Theses and Dissertations--Plant Pathology

Two thirds of plant viruses are positive-strand RNA viruses including the family Tombusviridae. One of the best-studied members of this family is Tomato bushy stunt virus (TBSV). Like many other viruses, TBSV has much fewer genes when compared to its hosts’ genome. Nevertheless, TBSV utilizes its genome very judiciously. To compensate for a lack of many proteins of its own, it codes for multi-functional replication protein p33 and also co-opts host factors to facilitate its replication.

By using recombinant replication proteins p33 and p92 containing single amino acid changes in protein-protein interaction domains (S1 and S2), I demonstrated that the …

The Sophistic Method?: Dialectic And Eristic In Legal Pedagogy, Thomas Cothran

Kentucky Law Journal

No abstract provided.

Cheap Meat: How Factory Farming Is Harming Our Health, The Environment, And The Economy, R. Jason Richards, Erica L. Richards

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

In Pari Delicto And Crop Gene Patents: An Equitable Defense For Innocently Infringing Farmers, David Costa

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Institutionalized Horse Abuse: The Soring Of Tennessee Walking Horses, Keith Dane

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Legal And Policy Issues Related To Anaerobic Digestion At United States Livestock Facilities, Jennifer C. Fiser

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

The Food Safety Modernization Act: Keeping Dinner Safe And Farmers In The Fields, Sarah K. Baker

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Equestrian Helmet Laws And Their Effect On Equestrian Liability, Litany Webster

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

A Dead Horse, You Can't Beat It: Equine Carcass Disposal Laws And Practices, Robert F. Dahlstrom, Kerry O'Neill Irwin, Emily J. Plant

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Down The Stretch: Reining In State Approaches Toward A Universal Medication Rule For Racehorses, Laurel Benson

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Consumer’S Motivation For Purchasing Fair Trade Clothing, Erika Ferrell

Theses and Dissertations--Retailing and Tourism Management

The purpose of this research is to determine if a consumer’s demographics, perceived consumer effectiveness, and awareness of fair trade practices affect their level of hedonic and utilitarian motivations that ultimately influence their purchase intentions. Two separate studies were conducted: a focus group and a survey. Middle-aged and older respondents were more motivated to buy fair trade clothing by both hedonic and utilitarian motivations than younger respondents. Respondents with only some college or an Associate’s degree are more hedonically motivated than other education levels. Respondents with a high household income are more motivated by their hedonic and utilitarian motivations than …

Kentucky Water Resources Research Institute Annual Technical Report Fy 2010, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The 2010 Annual Technical Report for Kentucky consolidates reporting requirements for the Section 104(b) base grant award into a single document that includes: 1) a synopsis of each research project that was conducted during the period, 2) citations for related publications, reports, and presentations, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable awards and achievements during the year.

Summary Of Kentucky River Watershed Watch 2011 Water Sampling Results, Kentucky Water Resources Research Institute

Kentucky River Watershed Watch

No abstract provided.

Snyder V. Phelps: A Hard Case That Did Not Make Bad Law, Paul E. Salamanca

Law Faculty Scholarly Articles

In Snyder v. Phelps, the Court stood by the First Amendment in hard times. A religious group conducted a protest some 1,000 feet from a fallen marine's funeral, holding such pickets as “God Hates the USA,” “Thank God for Dead Soldiers,” and “You're Going to Hell.” Despite the empathy that virtually anyone would feel for the marine's grieving father, the Court held by a vote of eight to one that his action for intentional infliction of emotional distress and intrusion upon seclusion could not survive, owing largely to the public nature of the issues the protesters had raised. “Hard …

Joseph Hersey Pratt, M.D.: The Man Who Would Be Osler, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Joseph Hersey Pratt (1872-1956) was a member of the second class of the Johns Hopkins Medical School, where he became a devoted student of William Osler and life-long disciple. Pratt received his medical degree in 1898 and spent his professional career in Boston. He maintained a close association with Osler until the latter's death in 1919, when Osler's deification as a secular medical saint began. When Pratt died in 1956 at age 83, the Boston Globe eulogized him in an editorial which read, "Dr. Pratt earned a place in the group of Boston medical immortals who have done so much …

Evaluation Of Mass Spectrometric Methods For Detection Of The Anti-Protozoal Drug Imidocarb, A. F. Lehner, J. A. Hitron, J. May, C. Hughes, R. Eisenberg, N. Schwint, D. P. Knowles, P. Timoney, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Imidocarb [N,N'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea, C₁₉H₂₀N₆O₁, m.w. 348.41] is a symmetrical carbanilide derivative used to treat disease caused by protozoans of the Babesia genus. Imidocarb, however, is also considered capable of suppressing Babesia-specific immune responses, allowing Babesia-positive horses to pass a complement fixation test (CFT) without eliminating the infection. This scenario could enable Babesia-infected horses to pass CFT-based importation tests. It is imperative to unequivocally identify and quantify equine tissue residues of imidocarb by mass spectrometry to address this issue. As a pretext to development of sensitive tissue assays, we have investigated possibilities of mass …

Kentucky Traffic Collision Facts 2011 Report, Kentucky Transportation Center, Kentucky State Police

Kentucky Transportation Center Research Report

KENTUCKY’S TRAFFIC COLLISION FACTS report for 2011 is based on collision reports submitted to the Kentucky State Police Records Branch. As required by Kentucky Revised Statutes 189.635, “every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.” The stated purpose of this requirement is to utilize data on traffic collisions for such purposes as will improve the traffic safety program in the Commonwealth. Data contained in this report are based solely on the observations …

Fish Oil And Barley Supplementation In Diets For Adult Dogs: Effects On Lipid And Protein Metabolism, Nutrient Digestibility, Fecal Quality, And Postprandial Glycemia, Maria Regina Cattai De Godoy

Theses and Dissertations--Animal and Food Sciences

Obesity is the most prevalent nutritional disorder encountered in small animal medicine. Problems related with obesity are the higher incidence of morbidity and mortality. Nutritional and physical activity interventions have been common strategies employed; however, they have shown low compliance rates. Because of it more attention has been given to the nutrient composition of diets. Using the canine model, three experiments were conducted to examine the effect of fish oil or barley on protein and lipid metabolism, as well as postprandial glycemia, and nutrient digestibility in mature and in young adult dogs.

In Exp. 1, seven female dogs were randomly …

Adaptation Of Lambs To An Endophyte Infected Tall Fescue Seed Diet, Rachel Ann Rickly Zinner

Theses and Dissertations--Animal and Food Sciences

Ten wether lambs were used to determine the effects of ergovaline consumption from endophyte infected tall fescue, on nutrient utilization and metabolism. Lambs were fed a diet of 23% endophyte free tall fescue seed (E-) and 77% concentrate from d -14 to -1 (adaptation phase). On d 0, five lambs were switched to an endophyte infected seed diet (E+) where they remained through d 14. Nutrient digestibilities tended to increase from adaptation through the acute (d 1 to 4) to subacute (d 10 to 14) phases when E- was fed. E+ digestibilities were highest (P < 0.05) in the acute phase. Lambs fed E+ had higher rectal temperatures in the acute (P < 0.01) and subacute phases (P < 0.05). Fecal recovery of ergovaline increased as day of collection increased in the acute and subacute phases. Lysergic acid fecal recovery increased with day of collection in the acute phase, but no effect was found in the subacute phase. Serum enzyme analyses did not indicate tissue damage from alkaloid consumption. These results demonstrate lambs try to adapt to endophyte infected fescue seed consumption through increased nutrient digestibilities and increased ergovaline and lysergic acid excretion.

Factors Affecting Skeletal Muscle Protein Synthesis In The Horse, Ashley Leigh Wagner

Theses and Dissertations--Animal and Food Sciences

Skeletal muscle protein synthesis is regulated by the mammalian target of rapamycin (mTOR) signaling pathway. The first objective was to optimize the methodological procedures for assessing mTOR signaling in horses. The response of mTOR signaling (P-Akt Ser⁴⁷³, P-S6K1 Thr³⁸⁹, P-rpS6 Ser^{235/26 & 240/244}, and P-4EBP1 Thr^37/46 by Western blotting techniques) to meal consumption was determined at three gluteal muscle biopsy depths (6, 8, and 10 cm), and the repeatability of the contralateral side at 8 cm during 5 days of repeated biopsies. There was no effect (P > 0.05) of sampling side or biopsy …

The Evolution Of Constitutional Environmental Law In Kenya, J. Bradley Larkin

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

The Constitutional Imperative Of Equitably Distributing The Proceeds Of Mineral Resource Extraction From China's Ethnic Minority Autonomous Areas, Lin Feng, Jason Buhi

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

The Healthy Monday Campaign: Health Awareness In Elementary Schools, Sheena Pravin Patel

Theses and Dissertations--Nutrition and Food Systems

Childhood obesity is a major public health concern for Americans. Many school-based health interventions and campaigns have been in place in the elementary school setting to help lower the rates of childhood obesity and to make students aware of their health. This study focuses on the implementation of the Healthy Monday campaign to fourth and fifth grade students in two Kentucky elementary schools. Particularly the focal points of the campaign consist of nutrition and physical activity. The campaign highlights two spin-off campaigns from the Healthy Monday campaign titled the Monday Mile and Meatless Monday. This study looks at the effectiveness …