Digital Commons Network^™

Prediction Model To Estimate The Zero Crossing Point For Faulted Waveforms, Md. Shakawat Hossan

Theses and Dissertations--Electrical and Computer Engineering

In any power system, fault means abnormal flow of current. Insulation breakdown is the cause of fault generation. Different factors can cause the breakdown: Wires drifting together in the wind, Lightning ionizing air, wires with contacts of animals and plants, Salt spray or pollution on insulators. The common type of faults on a three phase system are single line-to-ground (SLG), Line-to-line faults (LL), double line-to-ground (DLG) faults, and balanced three phase faults. And these faults can be symmetrical (balanced) or Unsymmetrical (imbalanced).In this Study, a technique to predict the zero crossing point has been discussed and simulated. Zero crossing point …

Robomirror: A Simulated Mirror Display With A Robotic Camera, Yuqi Zhang

Theses and Dissertations--Electrical and Computer Engineering

Simulated mirror displays have a promising prospect in applications, due to its capability for virtual visualization. In most existing mirror displays, cameras are placed on top of the displays and unable to capture the person in front of the display at the highest possible resolution. The lack of a direct frontal capture of the subject's face and the geometric error introduced by image warping techniques make realistic mirror image rendering a challenging problem. The objective of this thesis is to explore the use of a robotic camera in tracking the face of the subject in front of the display to …

Commentary On: "Facilitating Transparency In Spinal Cord Injury Studies Using Data Standards And Ontologies", Diane M. Snow

Spinal Cord and Brain Injury Research Center Faculty Publications

No abstract provided.

Are Major Repeater Patients Addicted To Suicidal Behavior?, Hilario Blasco-Fontecilla, Paula Artieda-Urrutia, Nuria Berenguer-Elias, Juan Manuel Garcia-Vega, Monica Fernandez-Rodriguez, Cesar Rodriguez-Lomas, Isabel Gonzalez-Villalobos, Luis Iruela-Cuadrado, Jose De Leon

Psychiatry Faculty Publications

The literature provides support for the hypothesis that some major repeaters (individuals with >=5 lifetime suicide attempts) are addicted to suicidal behavior (SB). This study explores whether major repeaters are addicted to SB or not using 7 criteria: tolerance (Criterion 1), withdrawal (Criterion 2), loss of control (Criterion 3), problems in quitting/cutting down (Criterion 4), much time spent using (Criterion 5), substantial reduction in activities (Criterion 6), and adverse physiological/physical consequences (Criterion 7). Total dependence on SB was indicated by the presence of 3 or more of the 7 criteria in the last 12 months. This cross-sectional study at Puerta …

Firesetting Behavior And Psychiatric Disorders, Stephanie Stockburger, Hatim A. Omar

Pediatrics Faculty Publications

Firesetting behavior results in serious damage to lives and property every year. Firesetting has been linked to a number of comorbid psychiatric disorders including depression, substance abuse, conduct disorder, antisocial personality disorder, obsessive compulsive disorder, psychotic disorder, schizoid personality disorder, and schizophrenia. Psychiatric disorders differ by gender. In addition, juvenile firesetters have history of a separate set of psychiatric comorbidities. The strong correlation between psychiatric comorbidities and firesetting behavior illustrates the need for fire service and mental health collaboration.

Self-Reported Juvenile Firesetting, Carrie Howell Bowling, Hatim A. Omar

Pediatrics Faculty Publications

In this chapter we address gaps in existing research by examining the relationship between academic performance and attention problems with juvenile firesetting. Two datasets from the Achenbach System for Empirically Based Assessment (ASEBA) were used. The Factor Analysis Dataset (N = 975) was utilized and results indicated that adolescents who report lower academic performance are more likely to set fires. Additionally, adolescents who report a poor attitude toward school are even more likely to set fires. Logistic regressions were run to determine if attention problems predicted firesetting and the findings indicated that attention problems are predictive of self-reported firesetting. The …

Academic Predictors And Characteristics Of Self-Reported Juvenile Firesetting, Carrie Howell Bowling, Hatim A. Omar

Pediatrics Faculty Publications

The main purpose of this study was to address gaps in existing research by examining the relationship between academic performance and attention problems with juvenile firesetting. Two datasets from the Achenbach System for Empirically Based Assessment (ASEBA) were used. The Factor Analysis Dataset (N = 975) was utilized and results indicated that adolescents who report lower academic performance are more likely to set fires. Additionally, adolescents who report a poor attitude toward school are even more likely to set fires. Logistic regressions were run to determine if attention problems predicted firesetting and the findings indicated that attention problems are predictive …

Mrp1: A Target For Hematopoietic Stem Cell Diseases, Cassandra Reiling

Theses and Dissertations--Toxicology and Cancer Biology

Multidrug resistance-associated protein 1 (MRP1) is a member of the adenosine 5’-triphosphate (ATP)-binding cassette (ABC) transporters. MRP1 actively effluxes a variety of endogenous and exogenous substrates from cells, ultimately, working to remove these compounds from the body. MRP1 was initially discovered based on its ability to confer resistance against a variety of chemotherapeutics when overexpressed in cancer cells lines. MRP1 function is important for a number of physiological processes, including regulating cellular and extracellular levels of the anti-inflammatory leukotriene C4 (LTC4) and the antioxidant glutathione (GSH). Our studies have focused on the role of MRP1 in regulating hematopoietic stem cell …

Distribution Of Wildlife Rabies In Central Appalachia And Analysis Of Factors Influencing Human Exposure, Sara J. Reilly

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Abstract Background: The rabies virus is a Lyssavirus of the family Rhabdoviridae which affects all mammals and causes progressive encephalomyelitis that is fatal in nearly one hundred percent of untreated cases. In the United States, wildlife act as the primary reservoir for rabies and prevention, surveillance, and control costs remain high. The purpose of this study is to understand the current distribution of wildlife rabies in Central Appalachia, as well as identify any demographic or geographic factors which may affect the risk of human exposure at the county level. Methods: A spatial statistical analysis using StatScan was performed to identify …

Training Teaching Assistants To Implement Systemic Teaching Strategies In Preschool Classrooms With Reliability, Rebecca V. Crawford

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

We are currently in an era of accountability, so the need for measuring fidelity of implementation is gaining attention. However, there is little research in the area of fidelity of implementation and an inclusive early childhood classroom. In addition, most of the research is conducted using teachers. This study examined the fidelity of implementation by two teaching assistants using the teaching strategies of time delay and system of least prompts with children with and without disabilities in an inclusive early childhood setting. A multiple-probe design with conditions across two behaviors and across two participants design was used to determine the …

Effect Of Dietary Exposure To Ergot Alkaloids On Contractility Of Bovine Mesenteric Vasculature And Rumen Motility, Amanda M. Egert

Theses and Dissertations--Animal and Food Sciences

Endophyte-infected (E+) tall fescue grass has been associated with fescue toxicosis, a costly syndrome characterized by poor cattle performance and health resulting in significant production losses. The fungal endophyte produces ergot alkaloids, which help the grass thrive in poor conditions but are toxic to mammals. A number of symptoms of fescue toxicosis can be related to vasoconstriction of bovine core, peripheral, and foregut vasculature. The first part of this series of experiments demonstrated ergot alkaloids were also vasoactive in midgut vasculature, with the exception of lysergic acid. Additionally, prior dietary exposure to ergot alkaloids decreased the contractile response of mesenteric …

Interaction Of Isoflavones And Endophyte-Infected Tall Fescue Seed Extract On Vasoactivity Of Bovine Mesenteric Vasculature, Yang Jia

Theses and Dissertations--Animal and Food Sciences

Endophyte-infected tall fescue produces many ergot alkaloids, which have been shown to be vasoconstrictive in various vessel types of bovine. On the other hand, substantial evidence has been reported on the vasodilative effects of formononetin and biochanin A in different vessel types in humans and rats. So, a study was conducted using mesenteric vasculature collected from heifers shortly after slaughter. After 2-h incubation with formononetin (F), biochanin A (B), or an ergovaline-containing tall fescue seed extract (EXT) and their combinations, vessels were mounted in a multi-myograph to determine their ergotamine-induced contractility. Results indicated that F and B at 1 × …

Effect Of Direct-Fed Microbials And Monensin On In Vitro Rumen Fermentation, Sheryl Wingard

Theses and Dissertations--Animal and Food Sciences

The impact of supplying a mixed culture of lactate producing bacteria on in-vitro rumen fermentation of forage- (Experiment 1) and concentrate- (Experiment 2) based diets in the presence and absence of monensin was explored. In experiment 1, interactions between DFM and MON were absent (P>0.10) for gas production and fermentative end products. Gas production and fermentative end products were unaffected by DFM alone (P>0.10). Monensin decreased (P<0.001) CH₄ and NH₃ production, rate and total gas production, as well as total VFA concentration and molar proportions of acetate and butyrate. However, MON increased (P<0.001) proportions of propionate, valerate, isobutyrate and isovalerate. Independently, DFM and MON increased (P<0.001) end point pH. In experiment 2, DFM x MON interactions or tendencies (P=0.07, P<0.01, P<0.01) were present, DFM effects were abated by MON, for rate, total gas production and total VFA concentrations. Acetate:propionate ratio was decreased (P<0.01) with MON and was unaffected by DFM. Ammonia-N concentration was increased (P<0.01) by DFM and unaffected (P=0.75) by MON. Both DFM and MON treatment increased (P<0.01) ruminal pH levels. These studies suggest the effects of DFM and MON of in-vitro fermentation are …

Evaluating Dietary Amino Acid Adequacy In Horses Using Isotopic Techniques, Sara L. Tanner

Theses and Dissertations--Animal and Food Sciences

Little is known about amino acid (AA) requirements in horses despite muscle mass accretion being of importance to an athletic species. Isotope methods for determining AA requirements and whole-body protein synthesis (WBPS) had not been previously used in growing horses. The first study herein was the first to apply isotope methods to determine WBPS in growing horses. In the study, weanling colts received two different levels of crude protein. Whole-body protein kinetics indicated that WBPS was greater when the weanlings were fed the diet with a greater crude protein content (P<0.05). The second study sought to determine a lysine requirement for yearling horses using the indicator AA oxidation (IAAO) method. Despite using six dietary levels of lysine; three above and three below the current recommendation, no breakpoint could be determined. Phenylalanine kinetics were not affected by lysine level (P>0.05), but plasma lysine increased linearly with lysine intake …

Procedural Predictability And The Employer As Litigator: The Supreme Court’S 2012-2013 Term, Scott R. Bauries

Law Faculty Scholarly Articles

In this contribution to the University of Louisville Law Review’s Annual Carl A. Warns Labor and Employment Institute issue, I examine the Supreme Court’s labor and employment-related decisions from the October Term 2012 (OT 2012). I argue that the Court’s decisions assisted employers as litigators—as repeat players in the employment dispute resolution system—in two ways. First, the Court established simple contract drafting strategies that employers may use to limit their exposure to employment claims. Second, the Court adopted bright-line interpretations of employment statutes. Both forms of assistance served a formalist interest in what I term “procedural predictability”—enhanced employer predictability and …

A Framework For Judicial Review And Remand In Immigration Law, Collin D. Schueler

Law Faculty Scholarly Articles

This Article breaks new ground at the intersection of administrative law and immigration law. One of the more important questions in both fields is whether a reviewing court should resolve a legal issue in the first instance or remand that issue to the agency. This Article advances the novel claim that courts should use the modem framework for judicial review of agency statutory interpretations to inform their resolution of this remand question. Then, using this framework, the Article identifies when remand is and is not appropriate in immigration cases. This critical analysis, which urges a departure from conventional academic wisdom, …

Texas Groundwater And Tragically Stable “Crossovers”, Zachary A. Bray

Law Faculty Scholarly Articles

One recurring question in the academic literature on common-pool resources relates to the persistence of “tragic” commons regimes—systems that encourage, or at least tolerate, the inefficient, wasteful, hazardous, or unfair exploitation of a resource that is easily accessed for and diminished by individual use and consumption. Of course, not all commons are tragic: some common-pool resources invite individual access in efficient, fair, and durable ways. Yet many commonly held resources do lie under systems of governance that are not just tragic but persistently and stubbornly so. Often the tragic aspects of such commons regimes are well known; indeed, for some …

Milk And Other Intoxicating Choices: Official State Symbol Adoption, Ryan A. Valentin

Law Faculty Scholarly Articles

Although the practice of adopting official state symbols is widespread, little has been written on what legislators, when tasked with choosing a state symbol, should take into consideration. An examination of select official state symbols of the Commonwealth of Kentucky will contribute to an understanding of what official state symbols are, the purpose they serve, the qualities they should reflect, and how the value of symbols adopted may be improved through the application of standard best practices.

Human Cardiovascular Responses To Artificial Gravity Variables: Ground-Based Experimentation For Spaceflight Implementation, Mark Howarth

Theses and Dissertations--Biomedical Engineering

One countermeasure to cardiovascular spaceflight deconditioning being tested is the application of intermittent artificial gravity provided by centripetal acceleration of a human via centrifuge. However, artificial gravity protocols have not been optimized for the cardiovascular system, or any other physiological system for that matter. Before artificial gravity protocols can be optimized for the cardiovascular system, cardiovascular responses to the variables of artificial gravity need to be quantified.

The research presented in this document is intended to determine how the artificial gravity variables, radius (gravity gradient) and lower limb exercise, affect cardiovascular responses during centrifugation. Net fluid (blood) shifts between body …

Considering The Human And Nonhuman In Literary Studies: Notes For A Biographic Network Approach For The Study Of Literary Objects, Edward L. Bullock

Theses and Dissertations--English

In recent years critical projects spanning philosophy, the social sciences, science studies, and nearly everywhere that has employed the term ecology have engaged in thinking humans and non-humans together as collectively producing outcomes, where objects do work beyond how humans perceive or make use of them. Taking Zelda Fitzgerald’s Save Me the Waltz as its focus, this thesis explores how this reorientation might contribute to literary studies and to literary criticism more specifically. The thesis considers a notion that novels constitute objects with biographies running “against” the biographic material of their authors, mobilizes actor network theory as a manner of …

Settling Mud, Running Streams, And “The Whole Thing About Men And Women”: Subverting Classical Discourse And The Role Of Character In Gertrude Stein’S “Melanctha”, Elizabeth D. S. Wise

Theses and Dissertations--English

The thesis begins by exploring Stein’s autobiographical connections to the Jamesian concepts of bottom nature and habit, in an attempt to demonstrate that both, in the pen of Gertrude Stein, are as connected to classical virtue theory and the development of character as a moral state and characters as created persons within her creative oeuvre, as they are connected to psychological experiments in William James’ laboratory. In wading through what may seem to be muddy waters of Stein’s slippery definitions and circular sentences, the thesis shows that Stein uses the discourse of classical virtue theory to achieve her goal—breaking down …

Development Of A Moldable Composite Bone Graft Substitute Releasing Antibacterial And Osteogenic Drugs, Matthew E. Brown

Theses and Dissertations--Biomedical Engineering

Large infected bone defects (IBD) are very complicated to treat due to their high variability; they often require multiple procedures. Bone autografts are the gold standard for treatment but have several drawbacks, such as a need for a second surgery site, limited grafting material, and donor site morbidity. The objective of this research was to develop a moldable synthetic bone grafting material capable of releasing both antimicrobial and osteogenic drugs over a clinically relevant time course for the treatment of IBDs. Current treatment methods for large IBDs require two separate procedures to treat the bone defect and the infection.

This …

Bioerodible Calcium Sulfate Bone Grafting Substitutes With Tailored Drug Delivery Capabilities, Bryan R. Orellana

Theses and Dissertations--Biomedical Engineering

Bone regeneration or augmentation is often required prior to or concomitant with implant placement. With the limitations of many existing technologies, a biologically compatible synthetic bone grafting substitute that is osteogenic, bioerodible, and provides spacing-making functionality while acting as a drug delivery vehicle for bioactive molecules could provide an alternative to ‘gold standard’ techniques.

In the first part of this work, calcium sulfate (CS) space-making synthetic bone grafts with uniformly embedded poly(β-amino ester) (PBAE) biodegradable hydrogel particles was developed to allow controlled release of bioactive agents. The embedded gel particles’ influence on the physical and chemical characteristics of CS was …

Mucoadhesive Films For Treatment Of Local Oral Disorders: Development, Characterization And In Vivo Testing, Sandeep K. Ramineni

Theses and Dissertations--Biomedical Engineering

Mucoadhesive drug delivery systems which are being used from 1980’s to avoid first pass metabolism of drugs, commercially exist for only systemic drug delivery with fast erosion times (15-60 min), that may not be appropriate for local oral disorders. The goal of this research was to develop and characterize mucoadhesive films with flexibility of carrying different drugs and proteins and provide sustained release for local treatment of oral disorders.

Mucoadhesive films composed of polyvinylpyrrolidone (PVP) and carboxymethlycellulose (CMC) were formulated with imiquimod, an immune response modifier. Problems such as solubilization of imiquimod to increase drug loading, uniformity in films and …

Clogging Of Fine Sediment Within Gravel Substrates: Macro-Analysis And Momentum-Impulse Model, Davis Huston

Theses and Dissertations--Civil Engineering

An understanding of the clogging of fine sediments within gravel substrates is advanced through the use of dimensional analysis and macro-analysis of clogging experiments in hydraulic flumes. Dimensional analysis is used to suggest that the dimensionless clogging depth can be collapsed using the original and adjusted bed-to-grain ratios, substrate porosity, roughness Reynolds number, and Peclet number. Macro-analysis followed by statistical analysis of 146 experimental test results of fine sediment deposition in gravel substrates suggests that the dimensionless clogging depth can be collapsed using the substrate porosity and roughness Reynolds number reflecting the processes of gravity settling and turbulence induced fluid …

Additives To Control Mechanical Properties And Drug Delivery Of Injectable Polymeric Scaffolds, Paul Fisher

Theses and Dissertations--Biomedical Engineering

In situ forming implants (ISIs) are popular due to their ease of use and local drug delivery potential, but they suffer from high initial drug burst, and release behavior is tied closely to solvent exchange and polymer properties. Additionally, such systems are traditionally viewed purely as drug delivery devices rather than potential scaffold materials due to their poor mechanical properties and minimal porosity. The aim of this research was to develop an injectable ISI with drug release, mechanical, and microstructural properties controlled by micro- and nanoparticle additives.

First, an injectable ISI was developed with appropriate drug release kinetics for orthopedic …

Cold Warriors In The Sunbelt: Southern Baptists And The Cold War, 1947-1989, Matthew J. Hall

Theses and Dissertations--History

Cold Warriors in the Sunbelt studies the ways in which the Cold War experience shaped the attitudes, values, and beliefs of white evangelicals in the South. It argues that for Southern Baptists in particular—the region’s most dominant religious majority—the Cold War provided a cohesive and unifying fabric that informed the world views Southern Baptists constructed, shaping how they interpreted everything from global communism, the black freedom movement, the Vietnam War, and controversies regarding the family and gender. This dissertation further contends that the Cold War experience, and the formative influence it had over several decades, laid the groundwork for the …

Determining Hillslope Diffusion Rates In A Boreal Forest: Quaternary Fluvial Terraces In The Nenana River Valley, Central Alaska Range, Laurel Anne Walker

Theses and Dissertations--Earth and Environmental Sciences

The subarctic boreal forest biome is predicted to experience higher magnitudes of warming than other biomes due to climate change. The effects of this warming will be pronounced in areas underlain by discontinuous permafrost where melting permafrost and distinct changes in vegetation patterns are expected. To better understand rates of hillslope diffusion in the boreal forest I have used a geomorphic process modeling approach, using data from a sequence of Quaternary fluvial terraces located in the Nenana River valley of central Alaska. I hypothesized that diffusion rates here would be slower when compared to the mid-latitudes, and faster on north …

Temporal And Spatial Characterization Of Macondo 252 Signatures In Gulf Of Mexico Shelf And Slope Sediments, Olivia P. Woodruff

Theses and Dissertations--Earth and Environmental Sciences

The long-term fate of hydrocarbons in the Gulf of Mexico (GOMx) following the 2010 Deepwater Horizon oil spill has yet to be fully characterized. Elemental (% C and % N), stable isotopes (δ¹³C_organic), and polycyclic aromatic hydrocarbon (PAH) molecular signatures were investigated in shelf and slope sediments collected in October 2010 and 2011 to gain insight into processes affecting the distribution and fate of spilled Macondo oil. Particulate organic carbon (POC) ranged between 1.55 and 2.22 wt. % in 2010 and 0.55 and 2.06 % in 2011 while the corresponding δ¹³C_organic ranges were …

A Petrographic Characterization Of The Leatherwood Coal Bed In Eastern Kentucky, Michelle N. Johnston

Theses and Dissertations--Earth and Environmental Sciences

The Eastern Kentucky Coal Field is located in the central portion of the Appalachian Basin. The Pennsylvanian Breathitt Formation in this region is characterized by numerous sequences of bituminous coal-bearing sedimentary rocks. These coals have distinct maceral compositions due to variations in depositional environments. Coal characterization is an important method for determining conditions that influenced peat accumulation and overall depositional settings of mires.

This study focuses on the characterization of the maceral composition of the Middle Pennsylvanian-age Leatherwood coal bed. It utilizes petrographical, palynological, and geochemical analyses to describe specific depositional environments and associated peat accumulation conditions.

Petrographic analyses indicate …