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Reversible Downregulation Of Hypothalamic-Pituitary-Gonadal Axis In The Stallion With A Third-Generation Gnrh Antagonist, Gabriel Monteiro Davolli

Theses and Dissertations--Veterinary Science

The objectives of this thesis were: (1) to evaluate the downregulation of the stallion hypothalamic-pituitary-gonadal (HPG) axis by a GnRH antagonist (acyline) based upon endocrine, seminal, testicular and behavioral effects, and (2) to assess recovery after treatment. Stallions were treated for 50 days (n=4; 330µg/kg acyline q 5d) and controls (n=4) received vehicle alone. Stallions were assessed pre-treatment and for 72 days after last treatment. Treatment induced declines (p<0.05) in FSH, LH, testosterone (to castrate levels) and estrone sulfate. Gonadotropins and testosterone returned to control values within nine days and estrone sulfate by 14 days after treatment discontinuation. Acyline-treated stallions failed to respond with FSH, LH and testosterone increase after exogenous GnRH stimulation (25µg gonadorelin, IV) compared to pre-treatment and control stimulation. Total sperm numbers and motility were reduced in acyline-treated stallions, as well as total seminal plasma protein and testicular volume (p<0.05). Time to ejaculation was increased in acyline group (p<0.5). Testicular, sexual behavior and most seminal parameters regained normal levels within 72 days after treatment ceased. Sperm output of acyline-treated stallions was regained within seven months after ending treatment. Acyline reversibly suppressed the stallion HPG axis, thus has potential for treating the androgen-dependent Equine-Arteritis-Virus carrier state and as behavior modulator.

Glucocorticoid-Induced Chondrocyte Cytotoxicity At Doses Recommended For Intra-Articular Therapy In Horses, Wenying Zhu

Theses and Dissertations--Veterinary Science

Intra-articular glucocorticoid injections are commonly used to treat synovitis and osteoarthritis in horses. These agents are highly effective at relieving pain, swelling, and other symptoms of joint inflammation. The drugs also have therapeutic benefits by down regulating the expression of cytokines and protease enzymes that participate in the degradation of articular cartilage. However, detrimental effects on chondrocyte function and cell viability that is independent of osteoarthritis pathogenesis have been described and linked to glucocorticoid use. These side effects are both drug- and dose-dependent. This study tested the hypothesis that manufacture recommended dosage levels of methylprednisolone, betamethasone, and triamcinolone that are …

Uterine Artery Rupture, An Angiopathy Of The Reproductive System Of The Mare: Occurrence And Potential Effects, Ana G. Toro Mayorga

Theses and Dissertations--Veterinary Science

The intent of this research was to identify if the degenerative changes within arteries in the endometrium (endometrial angiopathies) correlate with degenerative changes in the uterine arteries and can be used as a predictor of increased risk for uterine artery rupture (UAR). With this objective specimens from 20 mares that died from uterine artery rupture and 21 control mares that died from unrelated causes were obtained from cases submitted to the University of Kentucky Veterinary Diagnostic Laboratory (UKVDL) over a two-year period. Postmortem specimens of each mare were collected from the left and right uterine arteries at the origin, bifurcation, …

The Use Of Improved Technology And Market-Based Incentives To Increase Forest Resource And Biodiversity Conservation In Rwanda, Kelly M. Rayens

Theses and Dissertations--Forestry and Natural Resources

This study evaluated the effectiveness of two distinct approaches to ecosystem conservation in Rwanda’s Nyungwe National Park: cookstove technology adoption and market-based policy instruments. A June 2014 survey of 250 households revealed that use of improved cookstove technology dramatically decreased fuelwood consumption for households in rural Rwanda, but that design, engineering and conflicting policy issues can hamper the widespread use of energy-efficient cooking technology. The second component of this research used the analytic hierarchy process (AHP) within a multi-criteria analysis (MCA) framework to explore the options for designing and implementing market-based instruments around the country’s conservation targets, particularly the highly …

Invasiveness Of An Exotic Gall Wasp Is Influenced By Interactions With Exotic And Endemic Organisms, Ignazio Graziosi

Theses and Dissertations--Entomology

American chestnut was once a crucial component of North American forests, but it was functionally eliminated by the introduction of the chestnut blight fungus. Chestnut is recently experiencing resurgence, but the introduced Asian chestnut gall wasp, a specialist herbivore, threatens chestnut recovery. I characterized this invasion and the interactions developing with host associates as the gall wasp spread in North America. Gall wasp dispersal is attributable to host plant distribution, effects of prevailing winds during adult insect emergence, and to topography. This knowledge may be useful to more accurately predict locations of future gall wasp infestations. Gall wasp invasiveness is …

Evaluating A Novel Endophytic Grass For Its Potential To Reduce Invertebrate Populations And Associated Bird Strike Risk At Airports, Diana M. Miller

Theses and Dissertations--Entomology

Aircraft strikes are a significant safety hazard on airports worldwide. Wildlife management at airfields is the most effective tactic to reduce airstrike risk – to modify the habitat to be undesirable to animals. Tall fescue grasses containing a fungal symbiont may serve that purpose. They produce alkaloids that convey resistance to some grass-feeding invertebrates, which might in turn reduce incidence of insectivorous birds. A commercial endophytic grass (Avanex™) consisting of ‘Jackal’ tall fescue infected with a unique endophyte (AR 601) is purported to contain especially high levels of alkaloids and to reduce bird populations if planted at airports. I evaluated …

Mechanical Exclusion And Biological Control Strategies For The Invasive Brown Marmorated Stink Bug, Halyomorpha Halys (Hemiptera: Pentatomidae), Rachelyn Dobson

Theses and Dissertations--Entomology

The brown marmorated stink bug (Halyomorpha halys) is an invasive, agriculturally destructive pest present in most of the United States. Because organic farmers have few effective control options to combat this pest, three potential control options were investigated. Screens of different mesh sizes (0.42cm, 0.32cm, and 0.10cm) that covered vegetable crops were evaluated for their ability to exclude H. halys, allow the entry of beneficial insects, and protect the crop from various types of damage. H. halys and native stink bug egg masses were placed in an organic field and evidence of predation and parasitism from native …

Developing A Sustainable Approach To Emerald Ash Borer Management, William C. Davidson

Theses and Dissertations--Entomology

Emerald ash borer, Agrilus planipennis Fairmaire, is an invasive wood boring beetle native to eastern Asia which was first detected in North America in 2002. All North American Fraxinus (ash) species are suitable hosts and susceptible to attack. Emerald ash borer larvae feed on phloem beneath the bark of infested trees resulting in girdling and mortality in as little as five years following initial infestation. Since its introduction near Detroit, Michigan, emerald ash borer has rapidly spread throughout much of the United States and portions of Canada, threatening the persistence of ash in invaded regions.

I tested a management strategy …

Food Security Factors Affect Growth In Young Children In An Ecuadorian Indigenous Community, Whitney Jeannine Asher

Theses and Dissertations--Nutrition and Food Systems

Inadequate nutrition in preschool-aged children in an urban indigenous community outside of Santo Domingo, Ecuador has a negative impact on growth and development. Nutritional assessments have shown that children are underweight and that there are some effects of stunting and wasting in the population. This study was conducted to assess the extent of food security in this indigenous community in preparation for addressing two of the Millennium Development Goals for 2015: reducing the under-five child mortality rate by two-thirds and eradicating extreme poverty and hunger. An aim was to validate on-site assessment measures in this indigenous community regarding geographic circumstances, …

New Insights Into The Function And Development Of The Soldier Caste In Termites, Li Tian

Theses and Dissertations--Entomology

The evolution of nonreproductive castes is a defining characteristic of eusociality. The function and developmental regulation of the altruistic worker and soldier caste is the central element contributing to major advantages of eusociality over solitary animals. The soldier caste is the first evolved sterile caste in termites. Their primary function is believed to be colony defense. However, the function and development of termite soldiers remains largely unknown. Because of their apparent morphological adaptation for fighting and their limited behavior repertoire, our understanding of colony defense by termite soldiers is limited to their physical defense. In addition, we know little about …

Dietary Habits And Knowledge Of College Age Students, Matthew R. Majors

Theses and Dissertations--Nutrition and Food Systems

College is a time of emerging identity and habit formation for students. One hundred and sixty-two (162) college students were surveyed via an internet based survey. The survey asked questions regarding dietary habits such as consumption of dairy, vegetables, fruit, and protein. The survey also examined dietary knowledge such as ability to read food labels. The students were divided into two groups for analysis, nutrition majors and non-nutrition majors. The two groups differed in Body Mass Index (BMI) (p=0.004), but not nutrition knowledge (p=0.082). The nutrition students had an average BMI of 22.0+/-2.42 and a nutrition knowledge score of 2.44+/-0.60, …

Student Perceptions Of Organic Food In Relation To Health, Environment And Pricing, Stacey Paterson

Theses and Dissertations--Nutrition and Food Systems

The organic industry is full of opinions and perceptions, which influence consumer purchasing decisions. A convenience sample of 69 college students between the ages of 19-23 registered in a basic food preparation class participated in this study. A sensory analysis of organic and conventional fruits, vegetables, meat and poultry, eggs and dairy measuring categorical taste differences between the two types of food. Student perceptions of organic foods in relation to health, environment and pricing and the likelihood of purchase were also studied. The influence of Diet and Well-being on organic purchases predominantly mattered somewhat to students, while price mattered completely. …

High Quality Human 3d Body Modeling, Tracking And Application, Qing Zhang

Theses and Dissertations--Computer Science

Geometric reconstruction of dynamic objects is a fundamental task of computer vision and graphics, and modeling human body of high fidelity is considered to be a core of this problem. Traditional human shape and motion capture techniques require an array of surrounding cameras or subjects wear reflective markers, resulting in a limitation of working space and portability. In this dissertation, a complete process is designed from geometric modeling detailed 3D human full body and capturing shape dynamics over time using a flexible setup to guiding clothes/person re-targeting with such data-driven models. As the mechanical movement of human body can be …

Inducible Depletion Of Satellite Cells In Adult, Sedentary Mice Impairs Muscle Regenerative Capacity Without Affecting Sarcopenia, Christopher S. Fry, Jonah D. Lee, Jyothi Mula, Tyler J. Kirby, Janna R. Jackson, Fujun Liu, Lin Yang, Christopher L. Mendias, Esther E. Dupont-Versteegden, John J. Mccarthy, Charlotte A. Peterson

Physical Therapy Faculty Publications

A key determinant of geriatric frailty is sarcopenia, the age-associated loss of skeletal muscle mass and strength. Although the etiology of sarcopenia is unknown, the correlation during aging between the loss of activity of satellite cells, which are endogenous muscle stem cells, and impaired muscle regenerative capacity has led to the hypothesis that the loss of satellite cell activity is also a cause of sarcopenia. We tested this hypothesis in male sedentary mice by experimentally depleting satellite cells in young adult animals to a degree sufficient to impair regeneration throughout the rest of their lives. A detailed analysis of multiple …

Optimal Uses Of Biomass Resources In Distributed Applications, Joshua J. Jackson

Theses and Dissertations--Biosystems and Agricultural Engineering

Biomass production is spatially distributed resulting in high transportation costs when moving dedicated biomass crops and crop residues. A multifaceted approach was taken to address this issue as the low bulk and energy density of biomass limits transportation efficiency. Two systems were analyzed for the conversion of biomass into a denser feedstock applicable to on-farm use. Pelletization was able to densify the material into a solid fuel. Using a pilot scale flat ring pellet mill, the density of the material was able to be increased to at least 4.4 times that of uncompressed material. Pellet durability was found to be …

Characterization Of Two Biochars Derived From Horse Muck And Their Ability To Reduce Pathogen Transport In Soil, David Griffith

Theses and Dissertations--Biosystems and Agricultural Engineering

Biochars have been created and characterized from a variety livestock manure biomass including poultry, dairy, and swine. However, no research has been conducted on the physical and chemical makeup of biochar pyrolyzed from horse muck. Two horse muck derived biochars containing either straw (HS) or woodchip (HW) bedding were pyrolyzed at 700°C and characterized for their physical and chemical properties. Tests revealed both biochars had high alkalinity, moderate specific conductivity, and low surface area as compared to other biochars in the literature. HS contained more mineral structures than HW. Scanning electron microscopy presented differences in particle shape, size, and presence …

Towards Intelligent Telerobotics: Visualization And Control Of Remote Robot, Bo Fu

Theses and Dissertations--Computer Science

Human-machine cooperative or co-robotics has been recognized as the next generation of robotics. In contrast to current systems that use limited-reasoning strategies or address problems in narrow contexts, new co-robot systems will be characterized by their flexibility, resourcefulness, varied modeling or reasoning approaches, and use of real-world data in real time, demonstrating a level of intelligence and adaptability seen in humans and animals. The research I focused is in the two sub-field of co-robotics: teleoperation and telepresence. We firstly explore the ways of teleoperation using mixed reality techniques. I proposed a new type of display: hybrid-reality display (HRD) system, which …

Living On The Edge: Rethinking Pueblo Period: (Ad 700 – Ad 1225) Indigenous Settlement Patterns Within Grand Canyon National Park, Northern Arizona, Philip B. Mink Ii

Theses and Dissertations--Anthropology

This dissertation challenges traditional interpretations that indigenous groups who settled the Grand Canyon during the Pueblo Period (AD 700 -1225) relied heavily on maize to meet their subsistence needs. Instead they are viewed as dynamic ecosystem engineers who employed fire and natural plant succession to engage in a wild plant subsistence strategy that was supplemented to varying degrees by maize. By examining the relationship between archaeological sites and the natural environment throughout the Canyon, new settlement pattern models were developed. These models attempt to account for the spatial distribution of Virgin people, as represented by Virgin Gray Ware ceramics, Kayenta …

A Therapeutic Approach For Senile Dementias: Neuroangiogenesis, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Alzheimer's disease (AD) and related senile dementias (SDs) represent a growing medical and economic crisis in this country. Apart from cautioning persons about risk factors, no practical, effective therapy is currently available. Much of the recent research in AD has been based on the amyloid cascade theory. Another approach assumes a vascular basis for SDs. This paper presents evidence from a score of studies that cerebral capillary density (CCD) declines during old age in animals and people as well as in AD. Neuroangiogenic (NAG) factors initiate and maintain capillaries in the brain. Thus a waning level of these factors and …

Examining Memory Consolidation And Reconsolidation In An Appetitive Pavlovian Task, Jonathan J. Chow

Theses and Dissertations--Psychology

Memory plays an important role in defining how one behaves. The neurobiological mechanisms of memory have been studied extensively in animal models and the NMDA glutamate receptor has been identified to play an important role in the consolidation and reconsolidation of appetitive memories. Certain memories, depending on what was learned, can function differently and can be more difficult to disrupt based on a number of factors. Currently, no study has examined whether or not a reward-predictive stimulus attributed with incentive value is more difficult to disrupt than a stimulus that functions as a general reward-predictor. To determine the role of …

Front Matter [Preface And List Of Contributors], National Organizing Committee, International Grassland Congress

IGC Proceedings (1977-2023)

No abstract provided.

Promising Forage Options To Enhance Livestock Production In Mediterranean Climate Agricultural Systems, Serkan Ates, Hayley C. Norman, Hichem Ben Salem, Bradley Nutt, Harun Cicek

IGC Proceedings (1977-2023)

The increasing demand for food, fibre and animal products inevitably requires intensifying agricultural production worldwide. This can present a number of environmental and farming systems challenges in Mediterranean climate areas of the world. Developments of novel strategies, employing ecologically sound intensification practices, are crucial to enhance production in the Mediterranean agropastoral production systems. In this paper, we have discussed forage based systems that improve productivity, profitability, environmental quality and resilience of the farming systems. Key opportunities include better use and integration of diverse genetic resources, new agronomic techniques and the utilization of perennial forage plants that are adapted to land …

New Methodologies For Grasslands Monitoring, Katarzyna Dabrowska-Zielinska, Piotr Goliński, Marit Jorgensen, Jørgen Mølmann, Gregory Taff, Monika Tomaszewska, Barbara Golińska, Maria Budzynska, Martyna Gatkowska

IGC Proceedings (1977-2023)

Monitoring grassland areas to assess changes in their condition over time has been the subject of a lot of research at different scales. Initially the techniques focused on field-based measurements, and modelling. However, several obtained data were site specific. Based on the increase in availability of remote sensing data and products, there is an expectation that remote sensing can provide rapid and definite answers to the challenges of detecting and monitoring grassland conditions and associated changes in productivity. At the time of European Copernicus Programme, the new possibilities of satellite data from the group of Sentinel satellites give the new …

Grazing Management Options For Maintaining Optimum Pasture Composition And Utilization, Glen E. Aiken

IGC Proceedings (1977-2023)

Global demand for meat and dairy products will continue to increase over the 21st century, however, the global forage-based livestock industry will be challenged in meeting production goals with minimal impact of the environment. Sustainable production of grazing livestock will depend on the use of carefully planned grazing management strategies. Development of a grazing management plan involves making two decisions: determining the livestock density at which pastures are stocked and settling on the method used to graze the pastures. Stocking rate indirectly affects output per animal and per hectare through its direct effect on forage mass and pasture composition. A …

Enhancing Grassland Productivity Through Disease Management Of Grass And Forage Species, Tingyu Duan, Chunjie Li, Yanzhong Li, Binhua Yu, Zhibiao Nan

IGC Proceedings (1977-2023)

The total area of grassland in China is about 400 million hectares, accounting for 41.7% of the country’s land area, which plays important role in ecological construction and food security assurance of the national. However, diseases of grass and forage limited the development of the pastoral agriculture. There are more than1500 new diseases were reported in the past 16 years with more and more new diseases were discovered. The damage to grassland is becoming more severe with the known diseases prevalent areas expanding.

Management Of Pasture Soils: Biochar Stability, Carbon Storage Potential And Its Effect On Production And Quality, Bhupinder Pal Singh, Yunying Fang, Mark Boersma, Damian Collins, Lukas Van Zwieten, Lynne M. Macdonald

IGC Proceedings (1977-2023)

The use of biochar has been proposed as a stable carbon (C) amendment with long-term carbon (C) storage potential in agricultural soils while improving primary productivity. However, this concept has not been widely tested in contrasting soils under temperate pasture systems. To address this knowledge gap, a ¹³C-labelled biochar, produced from Eucalyptus saligna biomass by slow pyrolysis (450° C; d¹³C -36.7‰) was surface (0"10 cm) applied in C₃ dominated, annual temperate pasture systems across Arenosol, Cambisol and Ferralsol. The results show that only 2% of the applied biochar-C was mineralised in a relatively clay- and C-poor …

Grassland Renovation And Consequences For Nutrient Management, Johannes Isselstein, Manfred Kayser

IGC Proceedings (1977-2023)

Sward degradation is a serious threat to the functioning of grassland and the provision of ecosystem services. Renovation measures are frequently applied in order to restore degraded swards. However, the success is highly variable and substantial tradeoffs are often found following renovation such as among agronomic and environmental services. Starting from a general classification of renovation measures the paper investigates the processes induced by renovation that lead to a change of the vegetation and that affect carbon and nitrogen fluxes. These processes are strongly interrelated and dependent on site, climate and management condition as well as on the time scale. …

Impaired Glucose Metabolism In The Absence Of Skeletal Muscle Brain And Muscle Arnt-Like-Protein 1 (Bmal1), Brianna D. Harfmann

Theses and Dissertations--Physiology

Metabolism is a critical physiological function that works to generate energy for cells, store substrates and maintain homoeostasis. Alterations in normal metabolism can have a severe effect on physiology, leading to metabolic disease. Skeletal muscle is a key metabolic tissue, taking up ~80% of postprandial glucose. Therefore it contributes considerably to glucose metabolism: glucose uptake, oxidation and homeostasis. To address the role of the skeletal muscle clock in insulin sensitivity and glucose tolerance, our lab generated an inducible skeletal muscle specific Bmal1^-/- mouse (iMSBmal1^-/-). 5 weeks post-recombination we observed impairment in both insulin- and AICAR-stimulated skeletal …

A Comprehensive Method For Tuning And Pedaling Timpani, Brandon M. Arvay

Theses and Dissertations--Music

Method books are an integral part of the percussion pedagogy. Because of the vast number of instruments a modern percussionist is expected to play, they often look for progressive, concise, and effective resources that can make learning such a variety of instruments more efficient. Instructional books currently exist for many areas of percussion performance, including snare drum, mallet percussion, timpani, World music, accessories, and marching percussion. Included in these books are information and procedures on music reading, rhythm studies, listening skills, part preparation, and technical approach. Focusing on timpani methods specifically, many of these books include tuning and pedaling exercises …

Interdisciplinary Collaboration With Music Therapy During Routine Pediatric Dental Procedures, Austin S. Robinson

Theses and Dissertations--Music

The incorporation of integrative medicine into traditional treatment options has steadily increased during the past two decades. This has resulted in a change in the dynamics of interdisciplinary teams creating the need to better understand the roles and responsibilities of team members. The purpose of this study was to examine the perceptions of dental treatment team members regarding the role and responsibilities of music therapy during treatment.

A total of 10 participants were included in this study. Participants completed a pre-music therapy survey to establish prior knowledge, experience with, and perceptions of music therapy. Following an experiential intervention, participants completed …