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Volume 29: Populism, Aimee Imlay, Matthew Wentz Jul 2020

Volume 29: Populism, Aimee Imlay, Matthew Wentz

disClosure: A Journal of Social Theory

The 2019-2020 disClosure collective is thrilled to present the 29th volume of disClosure: A Journal of Social Theory. This volume focuses on theories of populism and brings together a wide range of perspectives relating to the phenomenon, experience, and study of populism. The recent uptick in populism signals political, economic, and/or social unrest across the globe, yet, populism remains a phenomenon that is difficult to define. Our goal with this volume was not to define populism. Instead, this issue engages conversations about the various types and origins of populisms, as it is our belief that the development and definition …

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Population Data-Driven Formulation Of A Covid-19 Therapeutic, Heather R. Campbell, Regan P. Cecil, Robert A. Lodder Jul 2020

Population Data-Driven Formulation Of A Covid-19 Therapeutic, Heather R. Campbell, Regan P. Cecil, Robert A. Lodder

Pharmaceutical Sciences Faculty Publications

This study is designed to utilize computer modeling of the US population through the ongoing CDC NHANES trial to reduce the need for preclinical formulation and toxicology studies of an Ebola antiviral (BSN389) being repurposed for COVID-19, and to thereby speed the candidate therapeutic to the clinic. BSN389 has poor solubility in water and that limits its bioavailability. BCD greatly increases the solubility of BSN389 and results in high bioavailability of BSN389 in animal studies. The goal of this study is to determine the current daily exposure of the population to beta cyclodextrin (BCD), and then keep the amount of …

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Patterns Of Inheritance Of Acylsugar Acyl Groups In Selected Interspecific Hybrids Of Genus Nicotiana, Antoaneta B. Mihaylova-Kroumova, Ivan Artiouchine, Victor D. Korenkov, George J. Wagner Jul 2020

Patterns Of Inheritance Of Acylsugar Acyl Groups In Selected Interspecific Hybrids Of Genus Nicotiana, Antoaneta B. Mihaylova-Kroumova, Ivan Artiouchine, Victor D. Korenkov, George J. Wagner

Kentucky Tobacco Research and Development Center Faculty Publications

Glandular trichomes on the surface of Solanaceae species produce acyl sugars that are species-, and cultivar-specific. Acyl sugars are known to possess insecticidal, antibiotic, and hormone-like properties, and as such have great potential as a class of naturally occurring pesticides and antibiotics. The objective of this work was to analyze the acyl composition of acyl sugars in the leaf trichome exudate from selected Nicotiana species and to follow the inheritance of acyl content in their hybrids. Trichome exudates were collected, and the acyl profiles of acyl sugars were identified via GC–MS. The variations in acyl group inheritance in the hybrids …

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Vehicle On Shoulder And Crash — Correlation Or Causation?, Mei Chen, Xu Zhang, Benjamin L. Blandford, Eugene Antwi Boasiako Jul 2020

Vehicle On Shoulder And Crash — Correlation Or Causation?, Mei Chen, Xu Zhang, Benjamin L. Blandford, Eugene Antwi Boasiako

Kentucky Transportation Center Research Report

This study sought to evaluate the relationships between vehicles on shoulder, congestion, and crashes. Three pertinent datasets on interstates were obtained and then integrated using a spatiotemporal approach. The analysis showed that about 36% of the crashes had vehicle on shoulder present in their vicinity, defined as 0.25 miles upstream and downstream of a crash site and 30 minutes before crash occurrence. The percentage increased considerably as spatial/temporal window expanded. In addition, congestion was found to be associated with about 25% of the crashes. The presence of both vehicle on shoulder and congestion was found for 11.7% of the crashes, …

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Assessment Of Important Environmental Factors Affecting Agropyron Trichophrum Establishment By Using An Ordination Method, Fazel Amiri, M. R. Chaichi, T. Tabatabai Jun 2020

Assessment Of Important Environmental Factors Affecting Agropyron Trichophrum Establishment By Using An Ordination Method, Fazel Amiri, M. R. Chaichi, T. Tabatabai

IGC Proceedings (1977-2023)

No abstract provided.

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Photosynthesis And Soil Respiration From A Mixed‐Grass Prairie: Effects Of Grazing And Drought, Xuejun Dong, Paul Nyren, Bob Patton, Guojie Wang, Brian Kreft, Anne Nyren, Ryan Limb, Don Kirby, Larry Cihacek Jun 2020

Photosynthesis And Soil Respiration From A Mixed‐Grass Prairie: Effects Of Grazing And Drought, Xuejun Dong, Paul Nyren, Bob Patton, Guojie Wang, Brian Kreft, Anne Nyren, Ryan Limb, Don Kirby, Larry Cihacek

IGC Proceedings (1977-2023)

No abstract provided.

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Electrochemical Evaluation Of A Multi-Site Clinical Depth Recording Electrode For Monitoring Cerebral Tissue Oxygen, Ana Ledo, Eliana Fernandes, Jorge E. Quintero, Greg A. Gerhardt, Rui M. Barbosa Jun 2020

Electrochemical Evaluation Of A Multi-Site Clinical Depth Recording Electrode For Monitoring Cerebral Tissue Oxygen, Ana Ledo, Eliana Fernandes, Jorge E. Quintero, Greg A. Gerhardt, Rui M. Barbosa

Neurosurgery Faculty Publications

The intracranial measurement of local cerebral tissue oxygen levels—PbtO2—has become a useful tool for the critical care unit to investigate severe trauma and ischemia injury in patients. Our preliminary work in animal models supports the hypothesis that multi-site depth electrode recording of PbtO2 may give surgeons and critical care providers needed information about brain viability and the capacity for better recovery. Here, we present a surface morphology characterization and an electrochemical evaluation of the analytical properties toward oxygen detection of an FDA-approved, commercially available, clinical grade depth recording electrode comprising 12 Pt recording contacts. We found that …

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Spermine Synthase And Myc Cooperate To Maintain Colorectal Cancer Cell Survival By Repressing Bim Expression, Yubin Guo, Qing Ye, Pan Deng, Yanan Cao, Daheng He, Zhaohe Zhou, Chi Wang, Yekaterina Y. Zaytseva, Charles E. Schwartz, Eun Young Lee, B. Mark Evers, Andrew J. Morris, Side Liu, Qing-Bai She Jun 2020

Spermine Synthase And Myc Cooperate To Maintain Colorectal Cancer Cell Survival By Repressing Bim Expression, Yubin Guo, Qing Ye, Pan Deng, Yanan Cao, Daheng He, Zhaohe Zhou, Chi Wang, Yekaterina Y. Zaytseva, Charles E. Schwartz, Eun Young Lee, B. Mark Evers, Andrew J. Morris, Side Liu, Qing-Bai She

Markey Cancer Center Faculty Publications

Dysregulation of polyamine metabolism has been linked to the development of colorectal cancer (CRC), but the underlying mechanism is incompletely characterized. Here, we report that spermine synthase (SMS), a polyamine biosynthetic enzyme, is overexpressed in CRC. Targeted disruption of SMS in CRC cells results in spermidine accumulation, which inhibits FOXO3a acetylation and allows subsequent translocation to the nucleus to transcriptionally induce expression of the proapoptotic protein Bim. However, this induction is blunted by MYC-driven expression of miR-19a and miR-19b that repress Bim production. Pharmacological or genetic inhibition of MYC activity in SMS-depleted CRC cells dramatically induces Bim expression and apoptosis …

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The Role Of Plant Richness & Diversity On Ecological Equilibrium Of Rangeland Habitats On Alborz Mountain (North Of Iran), D. Asgarizadeh, M. H. Jouri, V. Rahimi, J. Shahi Jun 2020

The Role Of Plant Richness & Diversity On Ecological Equilibrium Of Rangeland Habitats On Alborz Mountain (North Of Iran), D. Asgarizadeh, M. H. Jouri, V. Rahimi, J. Shahi

IGC Proceedings (1977-2023)

No abstract provided.

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Effect Of Nacl Concentration On Embryogenic Callus Growth And Plant Regeneration Of Pennisetum Purpureum Schumach (Napier Grass) In Vitro, Xiaoxian Zhong, Jianming She, Hongru Gu Jun 2020

Effect Of Nacl Concentration On Embryogenic Callus Growth And Plant Regeneration Of Pennisetum Purpureum Schumach (Napier Grass) In Vitro, Xiaoxian Zhong, Jianming She, Hongru Gu

IGC Proceedings (1977-2023)

No abstract provided.

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Grassland Sustainability And Livestock Production In Taipusi Banner, Inner Mongolia, Y. Zheng, David R. Kemp, Z. Xu, R. Jones, T. Takahashi, Q. Tian, T. Xilin Jun 2020

Grassland Sustainability And Livestock Production In Taipusi Banner, Inner Mongolia, Y. Zheng, David R. Kemp, Z. Xu, R. Jones, T. Takahashi, Q. Tian, T. Xilin

IGC Proceedings (1977-2023)

No abstract provided.

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Alteration Of Tobacco Alkaloid Content Through Modification Of Specific Cytochrome P450 Genes, Ralph E. Dewey, Balazs Siminszky, Steven W. Bowen, Lily Gavilano Jun 2020

Alteration Of Tobacco Alkaloid Content Through Modification Of Specific Cytochrome P450 Genes, Ralph E. Dewey, Balazs Siminszky, Steven W. Bowen, Lily Gavilano

Plant and Soil Sciences Faculty Patents

Compositions and methods for reducing the level of nornicotine and N'-nitrosonomicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic con- version of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use …

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Studies On Formation Classification And Composing Characteristic Of Helophyte In Maqu Meadow, China, Huaishan Zhang, Fuping Tian, Jinghua Li Jun 2020

Studies On Formation Classification And Composing Characteristic Of Helophyte In Maqu Meadow, China, Huaishan Zhang, Fuping Tian, Jinghua Li

IGC Proceedings (1977-2023)

No abstract provided.

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Effects Of Atriplex Canescens On Planted Areas In Iran, M. A. Zare Chahouki, Mohammad Jafari, Hossein Azarnivand, M. Shafi Zadeh Jun 2020

Effects Of Atriplex Canescens On Planted Areas In Iran, M. A. Zare Chahouki, Mohammad Jafari, Hossein Azarnivand, M. Shafi Zadeh

IGC Proceedings (1977-2023)

No abstract provided.

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Strategy Of Reproductive Allocation Of Stellera Chamae Jasme Population, F. Xing, J. X. Guo, Y. Wang, Y. Chen Jun 2020

Strategy Of Reproductive Allocation Of Stellera Chamae Jasme Population, F. Xing, J. X. Guo, Y. Wang, Y. Chen

IGC Proceedings (1977-2023)

No abstract provided.

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Plasmogamic Paternal Contributions To Early Zygotic Development In Flowering Plants, Yukinosuke Ohnishi, Tomokazu Kawashima Jun 2020

Plasmogamic Paternal Contributions To Early Zygotic Development In Flowering Plants, Yukinosuke Ohnishi, Tomokazu Kawashima

Plant and Soil Sciences Faculty Publications

Flowering plant zygotes possess complete developmental potency, and the mixture of male and female genetic and cytosolic materials in the zygote is a trigger to initiate embryo development. Plasmogamy, the fusion of the gamete cytoplasms, facilitates the cellular dynamics of the zygote. In the last decade, mutant analyses, live cell imaging-based observations, and direct observations of fertilized egg cells by in vitro fusion of isolated gametes have accelerated our understanding of the post-plasmogamic events in flowering plants including cell wall formation, gamete nuclear migration and fusion, and zygotic cell elongation and asymmetric division. Especially, it has become more evident that …

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Dynamic Change Of Production And Botanical Composition In Trifolium Repens And Perennial Grass Mixtures Over 20 Years In The Karst Region, Southwest China, Yuansu Wang, Fuzeng Hong, Qingrong Wa, Alan Mcdermott Jun 2020

Dynamic Change Of Production And Botanical Composition In Trifolium Repens And Perennial Grass Mixtures Over 20 Years In The Karst Region, Southwest China, Yuansu Wang, Fuzeng Hong, Qingrong Wa, Alan Mcdermott

IGC Proceedings (1977-2023)

No abstract provided.

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The Consequences Of Exercise-Induced Weight Loss On Food Reinforcement. A Randomized Controlled Trial, Kyle D. Flack, Harry M. Hays, Jack Moreland Jun 2020

The Consequences Of Exercise-Induced Weight Loss On Food Reinforcement. A Randomized Controlled Trial, Kyle D. Flack, Harry M. Hays, Jack Moreland

Dietetics and Human Nutrition Faculty Publications

BACKGROUND: Obesity remains a primary threat to the health of most Americans, with over 66% considered overweight or obese with a body mass index (BMI) of 25 kg/m2 or greater. A common treatment option many believe to be effective, and therefore turn to, is exercise. However, the amount of weight loss from exercise training is often disappointingly less than expected with greater amounts of exercise not always promoting greater weight loss. Increases in energy intake have been prescribed as the primary reason for this lack of weight loss success with exercise. Research has mostly focused on alterations in hormonal mediators …

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Prescribed Burning Based On Range Condition In The Okavango Delta Ramsar Site In Botswana, Africa, W. S. W. Trollope, L. A. Trollope, C. De B. Austin, A. C. Held Jun 2020

Prescribed Burning Based On Range Condition In The Okavango Delta Ramsar Site In Botswana, Africa, W. S. W. Trollope, L. A. Trollope, C. De B. Austin, A. C. Held

IGC Proceedings (1977-2023)

No abstract provided.

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Genome Diversity And The Origin Of The Arabian Horse, Elissa J. Cosgrove, Raheleh Sadeghi, Florencia Schlamp, Heather M. Holl, Mohammad Moradi-Shahrbabak, Seyed Reza Miraei-Ashtiani, Salma Abdalla, Ben Shykind, Mats H. T. Troedsson, Monika Stefaniuk-Szmukier, Anil Prabhu, Stefania Bucca, Monika Bugno-Poniewierska, Barbara Wallner, Joel Malek, Donald C. Miller, Andrew G. Clark, Douglas F. Antczak, Samantha A. Brooks Jun 2020

Genome Diversity And The Origin Of The Arabian Horse, Elissa J. Cosgrove, Raheleh Sadeghi, Florencia Schlamp, Heather M. Holl, Mohammad Moradi-Shahrbabak, Seyed Reza Miraei-Ashtiani, Salma Abdalla, Ben Shykind, Mats H. T. Troedsson, Monika Stefaniuk-Szmukier, Anil Prabhu, Stefania Bucca, Monika Bugno-Poniewierska, Barbara Wallner, Joel Malek, Donald C. Miller, Andrew G. Clark, Douglas F. Antczak, Samantha A. Brooks

Veterinary Science Faculty Publications

The Arabian horse, one of the world's oldest breeds of any domesticated animal, is characterized by natural beauty, graceful movement, athletic endurance, and, as a result of its development in the arid Middle East, the ability to thrive in a hot, dry environment. Here we studied 378 Arabian horses from 12 countries using equine single nucleotide polymorphism (SNP) arrays and whole-genome re-sequencing to examine hypotheses about genomic diversity, population structure, and the relationship of the Arabian to other horse breeds. We identified a high degree of genetic variation and complex ancestry in Arabian horses from the Middle East region. Also, …

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Preliminary Investigations On Columbus Grass (Sorghum Almum Parodi) For Fodder In Semi‐Arid Nigeria: Effects Of Sowing Methods On Growth Components And Herbage Yield, B. S. Malami, H. M. Tukur, H. Dahiru Jun 2020

Preliminary Investigations On Columbus Grass (Sorghum Almum Parodi) For Fodder In Semi‐Arid Nigeria: Effects Of Sowing Methods On Growth Components And Herbage Yield, B. S. Malami, H. M. Tukur, H. Dahiru

IGC Proceedings (1977-2023)

No abstract provided.

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Regional Phenotypic Differences Of The Opener Muscle In Procambarus Clarkii: Sarcomere Length, Fiber Diameter, And Force Development, Rachel C. Holsinger, Robin L. Cooper Jun 2020

Regional Phenotypic Differences Of The Opener Muscle In Procambarus Clarkii: Sarcomere Length, Fiber Diameter, And Force Development, Rachel C. Holsinger, Robin L. Cooper

Biology Faculty Publications

The opener muscle in the walking legs of the crayfish (Procambarus clarkii) has three distinct phenotypic regions although innervated by only one excitatory motor neuron. These regions (distal, central, and proximal) have varied biochemistry and physiology, including synaptic structure, troponin-T levels, fiber diameter, input resistance, sarcomere length, and force generation. The force generated by the central fibers when the excitatory neuron was stimulated at 40 Hz was more than the force generated by the other regions. This increase in force was correlated with the central fibers having longer sarcomeres when measured in a relaxed claw. These data support …

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Recent Shrinkage And Fragmentation Of Bluegrass Landscape In Kentucky, Bo Tao, Yanjun Yang, Jia Yang, S. Ray Smith, James F. Fox, Alex C. Ruane, Jinze Liu, Wei Ren Jun 2020

Recent Shrinkage And Fragmentation Of Bluegrass Landscape In Kentucky, Bo Tao, Yanjun Yang, Jia Yang, S. Ray Smith, James F. Fox, Alex C. Ruane, Jinze Liu, Wei Ren

Plant and Soil Sciences Faculty Publications

The Bluegrass Region is an area in north-central Kentucky with unique natural and cultural significance, which possesses some of the most fertile soils in the world. Over recent decades, land use and land cover changes have threatened the protection of the unique natural, scenic, and historic resources in this region. In this study, we applied a fragmentation model and a set of landscape metrics together with the satellite-derived USDA Cropland Data Layer to examine the shrinkage and fragmentation of grassland in the Bluegrass Region, Kentucky during 2008–2018. Our results showed that recent land use change across the Bluegrass Region is …

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Form Of Supplemental Selenium In Vitamin-Mineral Premixes Differentially Affects Early Luteal And Gestational Concentrations Of Progesterone, And Postpartum Concentrations Of Prolactin In Beef Cows, Sarah Carr, Yang Jia, Benjamin R. Crites, Charles Hamilton, Walter Burris, J. Lannett Edwards, James C. Matthews, Phillip J. Bridges Jun 2020

Form Of Supplemental Selenium In Vitamin-Mineral Premixes Differentially Affects Early Luteal And Gestational Concentrations Of Progesterone, And Postpartum Concentrations Of Prolactin In Beef Cows, Sarah Carr, Yang Jia, Benjamin R. Crites, Charles Hamilton, Walter Burris, J. Lannett Edwards, James C. Matthews, Phillip J. Bridges

Animal and Food Sciences Faculty Publications

Soils with marginal to deficient levels of selenium (Se) are widespread in the northwest, northeast, and southeast US. Supplementation to the diet of forage-grazing beef cattle with a vitamin-mineral mix containing additional Se is recommended in these geographic regions. We have reported that the form of supplemental Se provided to Angus-cross beef cows can affect circulating levels of progesterone (P4) on day 6 of the estrous cycle, a time when increased P4 is known to promote fertility. The objectives of this study were to (1) confirm and expand upon our initial report that the form of Se provided to cows …

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Kytc Maintenance Field Operations Guide Supplement, Bryan Gibson, Candice Y. Wallace, Nancy Albright, Christopher W. Van Dyke, Steven Douglas Kreis Jun 2020

Kytc Maintenance Field Operations Guide Supplement, Bryan Gibson, Candice Y. Wallace, Nancy Albright, Christopher W. Van Dyke, Steven Douglas Kreis

Kentucky Transportation Center Research Report

The Kentucky Transportation Cabinet (KYTC) is tasked with managing an asset portfolio that includes over 27,500 miles of roadway and 9,000 bridges. Keeping these assets in sound condition demands significant effort from KYTC’s Division of Maintenance, which includes activities ranging from mowing and litter pickup to cleaning out culverts and performing emergency roadway work. Despite the immense responsibilities shouldered by Maintenance personnel, until this project the Cabinet’s 12 districts lacked a systematic method for capturing and recording maintenance activities. Through a series of workshops held in each KYTC’s district with Section Engineer and Maintenance Supervisors, researchers at the Kentucky Transportation …

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Postnatal Loss Of The Insulin Receptor In Osteoprogenitor Cells Does Not Impart A Metabolic Phenotype, John L. Fowlkes, R. Clay Bunn, Evangelia Kalaitzoglou, Phil Ray, Iuliana Popescu, Kathryn M. Thrailkill Jun 2020

Postnatal Loss Of The Insulin Receptor In Osteoprogenitor Cells Does Not Impart A Metabolic Phenotype, John L. Fowlkes, R. Clay Bunn, Evangelia Kalaitzoglou, Phil Ray, Iuliana Popescu, Kathryn M. Thrailkill

Barnstable Brown Diabetes Center Faculty Publications

The relationship between osteoblast-specific insulin signaling, osteocalcin activation and gluco-metabolic homeostasis has proven to be complex and potentially inconsistent across animal-model systems and in humans. Moreover, the impact of postnatally acquired, osteoblast-specific insulin deficiency on the pancreas-to-skeleton-to-pancreas circuit has not been studied. To explore this relationship, we created a model of postnatal elimination of insulin signaling in osteoprogenitors. Osteoprogenitor-selective ablation of the insulin receptor was induced after ~10 weeks of age in IRl°x/lox/Osx-Cre+/− genotypic male and female mice (designated postnatal-OIRKO). At ~21 weeks of age, mice were then phenotypically and metabolically characterized. Postnatal-OIRKO mice demonstrated …

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Effects Of Endophyte Infection On The Response Of Achnatherum Inebrians To Water Stress And Nitrogen Fertilizer Under Controlled Growth Conditions, X. S. Li, X. Z. Zhang, X. Gu May 2020

Effects Of Endophyte Infection On The Response Of Achnatherum Inebrians To Water Stress And Nitrogen Fertilizer Under Controlled Growth Conditions, X. S. Li, X. Z. Zhang, X. Gu

IGC Proceedings (1977-2023)

No abstract provided.

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Sustainable Recultivation And Land Use On Karst Regions--Shrub System, Z. Q. Lai, S, M. Qin, Y. R. Chen, S. Z. Qin, M. Pogacnik, X. F. Yi, N. Yao, Y. L. Liang, D. Kompan, X. Su May 2020

Sustainable Recultivation And Land Use On Karst Regions--Shrub System, Z. Q. Lai, S, M. Qin, Y. R. Chen, S. Z. Qin, M. Pogacnik, X. F. Yi, N. Yao, Y. L. Liang, D. Kompan, X. Su

IGC Proceedings (1977-2023)

No abstract provided.

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Sustainable Recultivation And Land Use On Karst Regions--Pasture System, Z. Q. Lai, Y. R. Chen, M. Pogacnik, S. Z. Qin, X. F. Yi, N. Yao, Y. L. Liang, J. H. Deng, X. F. Zhang, B. Zhang, H. J. Zhong, D. Kompan, X. J. Lu, X. Su, D. Y. Shen May 2020

Sustainable Recultivation And Land Use On Karst Regions--Pasture System, Z. Q. Lai, Y. R. Chen, M. Pogacnik, S. Z. Qin, X. F. Yi, N. Yao, Y. L. Liang, J. H. Deng, X. F. Zhang, B. Zhang, H. J. Zhong, D. Kompan, X. J. Lu, X. Su, D. Y. Shen

IGC Proceedings (1977-2023)

No abstract provided.

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A Model For Managing An Endangered Species In Sandhills Rangeland, Kay L. Kottas, James Stubbendieck May 2020

A Model For Managing An Endangered Species In Sandhills Rangeland, Kay L. Kottas, James Stubbendieck

IGC Proceedings (1977-2023)

No abstract provided.

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