Digital Commons Network^™

Effects Of Endogenous Angiotensin Ii On Abdominal Aortic Aneurysms And Atherosclerosis In Angiotensin Ii-Infused Mice, Masayoshi Kukida, Hisashi Sawada, Satoko Ohno-Urabe, Deborah A. Howatt, Jessica J. Moorleghen, Marko Poglitsch, Alan Daugherty, Hong S. Lu

Saha Cardiovascular Research Center Faculty Publications

No abstract provided.

Intrauterine Blood Plasma Platelet-Therapy Mitigates Persistent Breeding-Induced Endometritis, Reduces Uterine Infections, And Improves Embryo Recovery In Mares, Lorenzo G. T. M. Segabinazzi, Igor F. Canisso, Giorgia Podico, Lais L. Cunha, Guilherme Novello, Michael F. Rosser, Shavanh C. Loux, Fabio S. Lima, Marco A. Alvarenga

Maxwell H. Gluck Equine Research Center Faculty Publications

Microorganisms, including pathogenic or opportunistic bacteria and fungi, may gain access to the uterus during breeding, and infectious endometritis plays a major role in equine subfertility. This study aimed to assess the post-breeding inflammatory response, endometrial culture, and embryo recovery of mares susceptible to persistent breeding-induced endometritis (PBIE) treated with plasma-rich (PRP) or -poor (PPP) plasma. Mares (n = 12) susceptible to PBIE had three cycles randomly assigned to receive intrauterine infusions of lactate ringer solution (LRS, control), or autologous PRP or PPP pre- (−48 and −24 h) and post-breeding (6 and 24 h). Mares were bred with fresh …

Polymers And Solvents Used In Membrane Fabrication: A Review Focusing On Sustainable Membrane Development, Xiaobo Dong, David Lu, Tequila A. L. Harris, Isabel C. Escobar

Chemical and Materials Engineering Faculty Publications

(1) Different methods have been applied to fabricate polymeric membranes with non-solvent induced phase separation (NIPS) being one of the mostly widely used. In NIPS, a solvent or solvent blend is required to dissolve a polymer or polymer blend. N-methyl-2-pyrrolidone (NMP), dimethylacetamide (DMAc), dimethylformamide (DMF) and other petroleum-derived solvents are commonly used to dissolve some petroleum-based polymers. However, these components may have negative impacts on the environment and human health. Therefore, using greener and less toxic components is of great interest for increasing membrane fabrication sustainability. The chemical structure of membranes is not affected by the use of different solvents, …

Scaffolding High-Impact Practices For Asian Studies And The Environment, Brett Werner, Kyle Anderson, Matthew Klooster, Daniel Kirchner, Aaron Godlaski

Lewis Honors College Faculty Publications

Support from the Henry Luce Foundation allowed a team of Centre College faculty to develop multiple integrated programs connecting the study of Asia to the environment: the Centre Summer Language Institute (CSLI), the Asia & the Environment Lab (A&E Lab), January term courses abroad, student summer research and internships abroad, and student dissemination of research. Each of these high-impact practices (HIPs) alone has been empirically demonstrated to enrich student experiences, but when linked in succession through a scaffolded framework, student learning was synergistically magnified. The personal growth, academic interests, and career trajectory of students who completed all stages of the …

A Genetic Diversity Analysis Of Wild Caragana Korshinskii Based On Allozyme And Aflp, Zan Wang, Xuemin Wang, Hongwen Gao

IGC Proceedings (1977-2023)

No abstract provided.

The Context-Dependent Impact Of Integrin-Associated Cd151 And Other Tetraspanins On Cancer Development And Progression: A Class Of Versatile Mediators Of Cellular Function And Signaling, Tumorigenesis And Metastasis, Sonia F. Erfani, Hui Hua, Yueyin Pan, Binhua P. Zhou, Xiuwei H. Yang

Molecular and Cellular Biochemistry Faculty Publications

As a family of integral membrane proteins, tetraspanins have been functionally linked to a wide spectrum of human cancers, ranging from breast, colon, lung, ovarian, prostate, and skin carcinomas to glioblastoma. CD151 is one such prominent member of the tetraspanin family recently suggested to mediate tumor development, growth, and progression in oncogenic context- and cell lineage-dependent manners. In the current review, we summarize recent advances in mechanistic understanding of the function and signaling of integrin-associated CD151 and other tetraspanins in multiple cancer types. We also highlight emerging genetic and epigenetic evidence on the intrinsic links between tetraspanins, the epithelial-mesenchymal transition …

Insects Provide Unique Systems To Investigate How Early-Life Experience Alters The Brain And Behavior, Rebecca R. Westwick, Clare C. Rittschof

Entomology Faculty Publications

Early-life experiences have strong and long-lasting consequences for behavior in a surprising diversity of animals. Determining which environmental inputs cause behavioral change, how this information becomes neurobiologically encoded, and the functional consequences of these changes remain fundamental puzzles relevant to diverse fields from evolutionary biology to the health sciences. Here we explore how insects provide unique opportunities for comparative study of developmental behavioral plasticity. Insects have sophisticated behavior and cognitive abilities, and they are frequently studied in their natural environments, which provides an ecological and adaptive perspective that is often more limited in lab-based vertebrate models. A range of cues, …

Biological And Economical Characteristics Of Galega Orientalis Lam, Zhongsheng Zhi, Wanquan Lian, Jianguang Wang, Weihua Gao, Yajun Zhi

IGC Proceedings (1977-2023)

No abstract provided.

Distribution Law And Utilizable Potentialities Of Three Kinds Of Clover Germplasm Resources In Xinjiang, Laixi Zhao, Yuqing Wang, Chunbo Xu, Ying De

IGC Proceedings (1977-2023)

No abstract provided.

Physiological Responses To Salt Stress At Seedling Stage In Festuca, Xinming Wu, Y. Q. Wang, J. N. Liu, P. Guo, Y. Zhang, H. W. Chi

IGC Proceedings (1977-2023)

No abstract provided.

Domestication Of Leymus Paboanus (Claus) Pilger, Dusu Wen, Hailian Sun, Chunli Bai, A. Lata

IGC Proceedings (1977-2023)

No abstract provided.

Study On Hybrid Selective Breeding Of High Quality Variety — Medicago Sativa L. Cv. Xinduo, Zhizhong Yang, Aikebar, Jie Li, Ming Din

IGC Proceedings (1977-2023)

No abstract provided.

Antibiotic Prescription Practices And Opinions Regarding Antimicrobial Resistance Among Veterinarians In Kentucky, Usa, Agricola Odoi, Ronita Samuels, Craig N. Carter, Jackie Smith

Veterinary Diagnostic Laboratory Faculty Publications

Background
Inappropriate antimicrobial use (AMU) is a global concern. Opinions of veterinarians regarding AMU and its role in the development of antimicrobial resistance (AMR) may influence their prescription practices. It is important to understand these opinions, prescription practices and their potential impact on the development of AMR in order to guide efforts to curb the problem. Therefore, the objective of this study was to investigate the antimicrobial prescription practices and opinions of veterinarians in Kentucky regarding AMU and AMR.

Methods
This cross-sectional study used a 30-question survey questionnaire administered to veterinarians who were members of the Kentucky Veterinary Medical Association. …

Functional Activation Of Newborn Neurons Following Alcohol-Induced Reactive Neurogenesis, Natalie N. Nawarawong, Chelsea G. Nickell, Deann M. Hopkins, James R. Pauly, Kimberly Nixon

Pharmaceutical Sciences Faculty Publications

Abstinence after alcohol dependence leads to structural and functional recovery in many regions of the brain, especially the hippocampus. Significant increases in neural stem cell (NSC) proliferation and subsequent “reactive neurogenesis” coincides with structural recovery in hippocampal dentate gyrus (DG). However, whether these reactively born neurons are integrated appropriately into neural circuits remains unknown. Therefore, adult male rats were exposed to a binge model of alcohol dependence. On day 7 of abstinence, the peak of reactive NSC proliferation, rats were injected with bromodeoxyuridine (BrdU) to label dividing cells. After six weeks, rats underwent Morris Water Maze (MWM) training then were …

Gait And Balance Changes With Investigational Peripheral Nerve Cell Therapy During Deep Brain Stimulation In People With Parkinson’S Disease, Geetanjali Gera, Zain Guduru, Tritia R. Yamasaki, Julie A. Gurwell, Monica Chau, Anna Krotinger, Frederick A. Schmitt, John T. Slevin, Greg A. Gerhardt, Craig G. Van Horne, Jorge E. Quintero

Physical Therapy Faculty Publications

Background: The efficacy of deep brain stimulation (DBS) and dopaminergic therapy is known to decrease over time. Hence, a new investigational approach combines implanting autologous injury-activated peripheral nerve grafts (APNG) at the time of bilateral DBS surgery to the globus pallidus interna. Objectives: In a study where APNG was unilaterally implanted into the substantia nigra, we explored the effects on clinical gait and balance assessments over two years in 14 individuals with Parkinson’s disease. Methods: Computerized gait and balance evaluations were performed without medication, and stimulation was in the off state for at least 12 h to best assess the …

Evaluation Of Native Ecotypes And Modern Cultivars Of Grasses And Legumes In Mongolia, D. Tumenjargal, D. Namkhai, B. Turtogtokh, N. Enkhtuya, L. Bayarmaa, D. Lkhagvasuren, Sodnomdarjaa Jigjidsuren

IGC Proceedings (1977-2023)

No abstract provided.

Prospects Of Triticale As Fodder And Feed In Farming Of Bangladesh, N. Tabassum, M. R. Uddin, U. S. Gim

IGC Proceedings (1977-2023)

No abstract provided.

Evaluation Of The Performance Of Seventeen Varieties Of Alfalfa (Medicago Sativa L), Yan Sun, Qingchuan Yang

IGC Proceedings (1977-2023)

No abstract provided.

Seed Rain And Viable Soil Seed Bank Of 'Black Soil Land' Degraded Alpine Meadow In Qinghai‐Tibetan Plateau, Zhanhuan Shang, Yushou Ma, Ruijun Long

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Sowing Methods And Seeding Rates On Chemical Composition Of Tephrosia Bracteolata, Olufemi S. Onifade, T. A. Amole, Alaba O. Jolaosho, O. M. Arigbede, Jimoh A. Olanite, U. Y. Anele, A. M. Oyeladun

IGC Proceedings (1977-2023)

No abstract provided.

Vitamin D Promotes Skeletal Muscle Regeneration And Mitochondrial Health, Christine M. Latham, Camille R. Brightwell, Alexander R. Keeble, Brooke D. Munson, Nicholas T. Thomas, Alyaa M. Zagzoog, Christopher S. Fry, Jean L. Fry

Athletic Training and Clinical Nutrition Faculty Publications

Vitamin D is an essential nutrient for the maintenance of skeletal muscle and bone health. The vitamin D receptor (VDR) is present in muscle, as is CYP27B1, the enzyme that hydroxylates 25(OH)D to its active form, 1,25(OH)D. Furthermore, mounting evidence suggests that vitamin D may play an important role during muscle damage and regeneration. Muscle damage is characterized by compromised muscle fiber architecture, disruption of contractile protein integrity, and mitochondrial dysfunction. Muscle regeneration is a complex process that involves restoration of mitochondrial function and activation of satellite cells (SC), the resident skeletal muscle stem cells. VDR expression is strongly upregulated …

Method For Designing Compounds And Compositions Useful For Targeting High Stoichiometric Complexes To Treat Conditions, Including Treatment Of Viruses, Bacteria, And Cancers Having Acquired Drug Resistance, Peixuan Guo, Dan Shu

Pharmaceutical Sciences Faculty Patents

A method is described for the identification o f multi-subunit biocomplex drug targets. The method includes identifying a target that performs a biological function, wherein the target comprises one or more subunits, wherein a minimum number of the one or more subunits is inactivated to inhibit the biological function. The method includes selecting a drug that binds specifically to each subunit of the one or more subunits with a target probability. The method describes a relationship between inhibition efficiency of the drug and total number of the one or more subunits using a binomial distribution, wherein the inhibition efficiency comprises …

Pyrrolizidine Alkaloid Content And Seed Toxicity In Crotalaria Species, J. A. Mosjidis, I. Khan, J. Hess

IGC Proceedings (1977-2023)

No abstract provided.

Indices To Volumes 8 - 13, Journal Of Natural Resources & Environmental Law

Journal of Natural Resources & Environmental Law

No abstract provided.

Risk Assessment, Redevelopment, And Environmental Justice: Evaluating The Brownfields Bargain, John S. Applegate

Journal of Natural Resources & Environmental Law

No abstract provided.

Radical Restructuring Of Environmental Policy To Preserve Biodiversity In Southern Africa: Malawi At The Crossroads, Tracy Dobson

Journal of Natural Resources & Environmental Law

No abstract provided.

Indices To Volumes 8 - 12, Journal Of Natural Resources & Environmental Law

Journal of Natural Resources & Environmental Law

No abstract provided.

Congress Should Exempt "Critical Habitat" Designation Under The Endangered Species Act From Compliance With The National Environmental Policy Act, Kurt Warmbier

Journal of Natural Resources & Environmental Law

No abstract provided.

Mountain States Legal Foundation V. Glickman: Disputes Over Timber Removal From National Forests, Elizabeth Monohan, Brian Wright

Journal of Natural Resources & Environmental Law

No abstract provided.

Danger For The Endangered Species Act?: Catron County Board Of Commissioners, New Mexico V. United States Fish And Wildlife Service, Richard W. Bertelson Iii

Journal of Natural Resources & Environmental Law

No abstract provided.