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Articles 3301 - 3330 of 12202
Full-Text Articles in Entire DC Network
People-Environment Trade-Offs In Managing Communal Rangelands Of South Africa, J. E. Bennett, S. Lemke, T. Marandure
People-Environment Trade-Offs In Managing Communal Rangelands Of South Africa, J. E. Bennett, S. Lemke, T. Marandure
IGC Proceedings (1977-2023)
Communal rangelands in South Africa support a range of ecosystem services including water provision, carbon sequestration and livestock production for different stakeholders. Delivering these in a sustainable and socially appropriate manner necessarily requires trade-offs to be made between the different environmental and social outcomes required. We draw on empirical fieldwork and a two-day participatory stakeholder workshop to report on the early stages of a project evaluating these trade-offs in communal rangelands of the uMzimvubu catchment in Eastern Cape Province. Our findings suggest that trade-offs will be necessary at a variety of different levels within this system. For example, a key …
Parasite Dynamics In Untreated Horses Through One Calendar Year, Ashley E. Steuer, Haley P. Anderson, Taylor Shepherd, Morgan Clark, Jessica A. Scare, Holli S. Gravatte, Martin K. Nielsen
Parasite Dynamics In Untreated Horses Through One Calendar Year, Ashley E. Steuer, Haley P. Anderson, Taylor Shepherd, Morgan Clark, Jessica A. Scare, Holli S. Gravatte, Martin K. Nielsen
Veterinary Science Faculty Publications
BACKGROUND: Horses are host to a plethora of parasites. Knowledge of the seasonality of parasite egg shedding and transmission is important for constructing parasite control programs. However, studies describing these patterns are sparse, and have largely been conducted only in the United Kingdom. This study evaluated strongylid egg shedding patterns and transmission dynamics of Strongylus vulgaris in naturally infected and untreated mares and foals through one calendar year in Kentucky, USA. The study also investigated the existence of a peri-parturient rise (PPR) in strongylid egg counts in foaling mares and collected information about Strongyloides westeri and Parascaris spp. in the …
Prostacyclin Promotes Degenerative Pathology In A Model Of Alzheimer’S Disease, Tasha R. Womack, Craig T. Vollert, Odochi Ohia-Nwoko, Monika Schmitt, Saghi Montazari, Tina L. Beckett, David Mayerich, M. Paul Murphy, Jason L. Eriksen
Prostacyclin Promotes Degenerative Pathology In A Model Of Alzheimer’S Disease, Tasha R. Womack, Craig T. Vollert, Odochi Ohia-Nwoko, Monika Schmitt, Saghi Montazari, Tina L. Beckett, David Mayerich, M. Paul Murphy, Jason L. Eriksen
Molecular and Cellular Biochemistry Faculty Publications
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is the most common form of dementia in aged populations. A substantial amount of data demonstrates that chronic neuroinflammation can accelerate neurodegenerative pathologies. In AD, chronic neuroinflammation results in the upregulation of cyclooxygenase and increased production of prostaglandin H2, a precursor for many vasoactive prostanoids. While it is well-established that many prostaglandins can modulate the progression of neurodegenerative disorders, the role of prostacyclin (PGI2) in the brain is poorly understood. We have conducted studies to assess the effect of elevated prostacyclin biosynthesis in a mouse model of AD. Upregulated prostacyclin expression …
Using Low-Fix Rate Gps Telemetry To Expand Estimates Of Ungulate Reproductive Success, Nathan D. Hooven, Kathleen E. Williams, John T. Hast, Joseph R. Mcdermott, R. Daniel Crank, Gabe Jenkins, Matthew T. Springer, John J. Cox
Using Low-Fix Rate Gps Telemetry To Expand Estimates Of Ungulate Reproductive Success, Nathan D. Hooven, Kathleen E. Williams, John T. Hast, Joseph R. Mcdermott, R. Daniel Crank, Gabe Jenkins, Matthew T. Springer, John J. Cox
Forestry and Natural Resources Faculty Publications
Background
Population parameters such as reproductive success are critical for sustainably managing ungulate populations, however obtaining these data is often difficult, expensive, and invasive. Movement-based methods that leverage Global Positioning System (GPS) relocation data to identify parturition offer an alternative to more invasive techniques such as vaginal implant transmitters, but thus far have only been applied to relocation data with a relatively fine (one fix every < 8 h) temporal resolution. We employed a machine learning method to classify parturition/calf survival in cow elk in southeastern Kentucky, USA, using 13-h GPS relocation data and three simple movement metrics, training a random forest on cows that successfully reared their calf to a week old.
Results
We developed a decision rule based upon a predicted probability threshold across individual cow time series, accurately classifying 89.5% (51/57) of cows with a known reproductive status. When used to infer status of …
How Does N Fertilization Or Forage Legumes Affect Forage And Animal Production?, B. G. C. Homem, I. B. G. Lima, P. P. Spasiani, José C. B. Dubeux Jr., R. M. Boddey, D. R. Casagrande
How Does N Fertilization Or Forage Legumes Affect Forage And Animal Production?, B. G. C. Homem, I. B. G. Lima, P. P. Spasiani, José C. B. Dubeux Jr., R. M. Boddey, D. R. Casagrande
IGC Proceedings (1977-2023)
Livestock grazing in tropical climates is characterized by low productivity. Forage and animal production can be improved by applying nitrogen (N) fertiliser or using forage legumes. This 2.5-yr study assessed the canopy structure and productivity of beef cattle grazing either a mixed pasture of Brachiaria brizantha cv. Marandu (palisadegrass) and Arachis pintoi (forage peanut) cv. BRS Mandobi or a Marandu palisade grass monoculture with or without N fertilisation. The experiment was carried out in Southeast Brazil, where the canopy structure (herbage mass) and animal productivity (stocking rate and liveweight gain per ha) were compared for three types of pastures: 1) …
Managing Vegetation In Grasslands Habitats To Meet Livestock Or Wildlife Objectives, B. Sleugh, S. Flynn, D. C. Cummings, W. Hatler, D. Hillger, C. Hart
Managing Vegetation In Grasslands Habitats To Meet Livestock Or Wildlife Objectives, B. Sleugh, S. Flynn, D. C. Cummings, W. Hatler, D. Hillger, C. Hart
IGC Proceedings (1977-2023)
Sustainably stewarding grassland systems involves applying various practices to manipulate forage interactions with other plants, the environment, and grazing animals to meet resource manager objectives. These interactions can result in invasion or encroachment and increased abundance of weeds which hinder attainment of management objectives. Weeds influence the structure and function of pasture ecosystems whether forages are grown in improved pastures, rangeland, or grassland communities. They degrade pasture quality and reduce livestock performance by interfering with forage establishment, yield, and quality by competing for resources. Weeds reduce the feed value of forage, decrease pasture carrying capacity, and can be toxic or …
Improving Pasture Productivity And Persistence By Renovating Or Rejuvenating, A. Omokanye, D. Westerlund, G. Hernandez-Ramirez
Improving Pasture Productivity And Persistence By Renovating Or Rejuvenating, A. Omokanye, D. Westerlund, G. Hernandez-Ramirez
IGC Proceedings (1977-2023)
Forages make up a large part of the feed requirements of beef cattle, and grazing remains the most economical form of feed delivery. However, several years after pasture establishment, forage productivity and longevity usually decline. Maintaining productive forage stands in the long term becomes a major challenge that beef producers face. A 3-yr on-farm study was conducted to determine the comparative effects of several pasture rejuvenation methods, such as spraying of herbicides to control weeds and brush, Spray herbicide + direct seed in spring (RSS), forage seeding methods, fertilizer application (FERT), and pasture rest as well as aeration/spiking in fall …
Improving Forage Production Quantity And Quality Using Native Legume Species In Semi-Arid Agrosilvopastoral System, M. Louhaichi, S. Slim, M. Gamoun, S. Hassan, J. Kailene, I. Hamdaoui
Improving Forage Production Quantity And Quality Using Native Legume Species In Semi-Arid Agrosilvopastoral System, M. Louhaichi, S. Slim, M. Gamoun, S. Hassan, J. Kailene, I. Hamdaoui
IGC Proceedings (1977-2023)
Agrosilvopastoral systems provide a range of livelihood services, either directly through forage production or indirectly by the beneficial effects on soil conservation, nutrient cycling, pollutant filtering, and biodiversity enhancement. Hence, improved silvopastoral systems have ample scope to rehabilitate degraded pastures to sustain livestock production, which remains a strong pillar for the livelihoods of the agrosilvopastoral communities. To evaluate the impact of Hedysarum coronarium L. (sulla) reseeding on pasture productivity, plant cover and plant density in semi-arid silvopastoral systems, an experiment was carried out in Sbaihia Site, Zaghouan Governorate, Tunisia during 2018-2019 growing season. The experiment was laid out under a …
Improvement Of Feeding Value Of Quinoa Stalk With White Rot Fungi Treatment, M. Hanada, T. Egi, S. Muyila, J. Njiolomba, Y. Tokura
Improvement Of Feeding Value Of Quinoa Stalk With White Rot Fungi Treatment, M. Hanada, T. Egi, S. Muyila, J. Njiolomba, Y. Tokura
IGC Proceedings (1977-2023)
Two trials were conducted to evaluate the effect of white rot fungi treatment on feeding value of quinoa stalk. In trial 1, quinoa stalk was inoculated with Pleurotus osteratus (PO) or Pleurotus citrinopileatus (PC) at 25 °C for 90 days, and chemical composition and hardness of the stalk were measured. In trial 2, quinoa stalk was inoculated with PO, and incubated at 10 and 25 °C for 60, 90 and 120 days. After incubation, the chemical composition and hardness of the stalk were measured. In trial 1, acid detergent lignin (ADL) content in the stalk decreased in both treatments, and …
Impact Of Abnormal Climate Events On The Production Of Italian Ryegrass As A Season In The Republic Of Korea, M. Kim, J. Y. Kim, M. H. Jo, H. Jo, K. Sung
Impact Of Abnormal Climate Events On The Production Of Italian Ryegrass As A Season In The Republic Of Korea, M. Kim, J. Y. Kim, M. H. Jo, H. Jo, K. Sung
IGC Proceedings (1977-2023)
This study aimed to assess the impact of abnormal climate events on the production of Italian ryegrass (IRG), such as autumn low-temperature, severe winter cold and spring droughts in the central inland, southern inland and southern coastal regions. Seasonal climatic variables, including temperature, precipitation, wind speed, relative humidity, and sunshine duration, were used to set the abnormal climate events using principal component analysis, and the abnormal climate events were distinguished from normal using Euclidean-distance cluster analysis. Furthermore, to estimate the impact caused by abnormal climate events, the dry matter yield (DMY) of IRG between abnormal and normal climate events was …
Global Assessment Of Grassland Carrying Capacities And Relative Stocking Densities Of Livestock, J. Piipponen, M. Jalava, J. De Leeuw, A. Rizayeva, C. Godde, M. Herrero, M. Kummu
Global Assessment Of Grassland Carrying Capacities And Relative Stocking Densities Of Livestock, J. Piipponen, M. Jalava, J. De Leeuw, A. Rizayeva, C. Godde, M. Herrero, M. Kummu
IGC Proceedings (1977-2023)
Although many suggest that future diets should include more plant-based proteins, animal-sourced foods are unlikely to completely disappear from our diet. Grasslands yield a notable part of the world’s animal protein production, but thus far, there is no global insight into the relationship between current livestock stocking densities and the availability of grassland forage resources. This inhibits acting upon concerns over the negative effects of overgrazing in some areas and utilising the potential for increasing production in others. Previous research has examined the potential of sustainable grazing but lacks generic and observation-based methods needed to fully understand the opportunities and …
Design, Development, And Validation Of An Augmented Reality-Enabled Production Strategy Process, Hala Nassereddine, Dharmaraj Veeramani, Awad S. Hanna
Design, Development, And Validation Of An Augmented Reality-Enabled Production Strategy Process, Hala Nassereddine, Dharmaraj Veeramani, Awad S. Hanna
Civil Engineering Faculty Publications
The Production Strategy Process (PSP) is an integral part of production planning and control as it defines how production processes are structured and designed and outlines how production will be executed. PSP involves massive information transfer and communication among project participants. While BIM can improve the flow of information, the paradox of designing 3D models in 2D space remains. This paradox indicates that new visualization technologies are needed to leverage the use of information in the PSP. As Industry 4.0, the fourth industrial revolution, continues to evolve, it is imperative that construction firms seek, find, and adopt new technologies. This …
Evaluation Of Microbial Biomass In Agroforestry Systems Using Forage Cactus And Leucaena Leucocephala And Gliricidia Sepium, Dayanne Camelo, José C. B. Dubeux Jr., Mario De Andrade Lira Jr., Mércia V. F. Dos Santos, Diana Valadares Pessoa, Erick Santos
Evaluation Of Microbial Biomass In Agroforestry Systems Using Forage Cactus And Leucaena Leucocephala And Gliricidia Sepium, Dayanne Camelo, José C. B. Dubeux Jr., Mario De Andrade Lira Jr., Mércia V. F. Dos Santos, Diana Valadares Pessoa, Erick Santos
IGC Proceedings (1977-2023)
Vegetation type can affect soil microbiology in agroforestry systems. Plants release different organic exudates in the rhizosphere, affecting microbial growth. This study evaluated the effect of forage cactus intercropped with different tree legumes on soil microbial biomass. The research was performed in a tropical semiarid Regosol at Caruaru Experimental Station, Agronomic Institute of Pernambuco, Northeast Brazil. Treatments included: i) Gliricidia sepium (Jacq.) Steud and forage cactus IPA-Sertânia (Nopalea cochenillifera Salm Dyck); and ii) Leucaena leucocephala [Lam.] de Wit.) and forage cactus IPA-Sertânia. Treatments were allocated in a randomized complete block design in a split-split-plot scheme, with four replications. Main …
Elephants Mitigate The Effects Of Cattle On Wildlife And Other Ecosystem Traits: Experimental Evidence, Truman P. Young, Duncan N. Kimuyu, Kari E. Veblen, Corinna Riginos, Judith Sitters, Lauren Porensky, Wilfred O. Odadi
Elephants Mitigate The Effects Of Cattle On Wildlife And Other Ecosystem Traits: Experimental Evidence, Truman P. Young, Duncan N. Kimuyu, Kari E. Veblen, Corinna Riginos, Judith Sitters, Lauren Porensky, Wilfred O. Odadi
IGC Proceedings (1977-2023)
On rangelands worldwide, cattle interact with many ecosystem components, most obviously with soils, plants, and other large herbivores. Since 1995, we have been manipulating the presence of cattle, mesoherbivores, and megaherbivores (elephants and giraffes) in a series of eighteen 4-ha (10-acre) plots at the Kenya Long-term Exclosure Experiment. We have demonstrated a wide array of cattle effects on this savanna rangeland, including their reduction of grass cover, wildlife use, and soil nitrogen and phosphorus pools, but their increase of primary productivity and termite abundance. Strikingly, we demonstrate that the presence of mega-herbivores (elephants, mainly) reduces the sizes of these cattle. …
Apoe Genetics Influence Murine Gut Microbiome, Diana J. Zajac, Stefan J. Green, Lance A. Johnson, Steven Estus
Apoe Genetics Influence Murine Gut Microbiome, Diana J. Zajac, Stefan J. Green, Lance A. Johnson, Steven Estus
Physiology Faculty Publications
Apolipoprotein E (APOE) alleles impact pathogenesis and risk for multiple human diseases, making them primary targets for disease treatment and prevention. Previously, we and others reported an association between APOE alleles and the gut microbiome. Here, we evaluated effects of APOE heterozygosity and tested whether these overall results extended to mice maintained under ideal conditions for microbiome analyses. To model human APOE alleles, this study used APOE targeted replacement (TR) mice on a C57Bl/6 background. To minimize genetic drift, homozygous APOE3 mice were crossed to homozygous APOE2 or homozygous APOE4 mice prior to the study, and the resulting …
Nutritive Evaluation Of Mulberry Leaves Based Apple Pomace Silage, Ngahanyui Kengoo, Rohit Bishist
Nutritive Evaluation Of Mulberry Leaves Based Apple Pomace Silage, Ngahanyui Kengoo, Rohit Bishist
IGC Proceedings (1977-2023)
The present study was conducted to evaluate the nutritive value of mulberry leaves based apple pomace silage in Dr Y S Parmar University of Horticulture and Forestry, Nauni, Solan, Himachal Pradesh, India. In the study, the silage was prepared by mixing of maize, apple pomace (AP) and mulberry leaves in ratios of 80:10:10 (T1), 70:20:10(T2) and 60:30:10 (T3), and mixing of apple pomace with wheat straw in the ratio of 85:15(T4), and the silage prepared by using 100 per cent chopped maize was taken as control. Silage bags were opened after a period of three months and the proportionate samples …
Dairy Cattle Genetics By Environment Interaction Mismatch Contributes To Poor Mitigation And Adaptation Of Grazing Systems To Climate Change Actions In The Peruvian High Andes: A Review, V. M. Velez Marroquin, J. Manhire, R. Garcia Ticllacuri, J. L. Bernal Madrid, C. S. Pinares-Patino
Dairy Cattle Genetics By Environment Interaction Mismatch Contributes To Poor Mitigation And Adaptation Of Grazing Systems To Climate Change Actions In The Peruvian High Andes: A Review, V. M. Velez Marroquin, J. Manhire, R. Garcia Ticllacuri, J. L. Bernal Madrid, C. S. Pinares-Patino
IGC Proceedings (1977-2023)
The high Andes of Peru includes fragile ecosystems. Nevertheless, it plays important ecosystem functions (e.g., biodiversity, water supply for the lowlands, CO2 sinks in soil, etc). More than 80% of the livestock population of Peru is farmed in this area, supporting the livelihood of approximately 1’400,000 poor families, who are vulnerable to climate change (CC). Climate change in the high Andes is occurring at accelerated rates, compared to lowlands regions. Prevalent factors in the high Andes, such as hypoxia, high UV radiation, climatic extremes, large variation between maximum and minimum temperatures, seasonality in rainfall (determining highly seasonal forage growth) …
Exploring The Variation In Spatial Landscape Utilisation By Cows In The Pre- And Post-Partum Period Using Gnss Technology, A Z. Chang, M. G. Trotter
Exploring The Variation In Spatial Landscape Utilisation By Cows In The Pre- And Post-Partum Period Using Gnss Technology, A Z. Chang, M. G. Trotter
IGC Proceedings (1977-2023)
On-animal sensors refer to systems that monitor the location, behaviour, or physiological characteristics of livestock. These technologies provide a method to overcome many of the challenges that are associated with monitoring livestock within an extensive grazing system. A global navigation satellite system (GNSS) could be used to detect the changes in spatial utilisation associated with when a cow has a calf at foot. In this study, forty pregnant Belmont Red heifers were fitted with GNSS collars programmed to provide a location reading at 5 minute intervals. The data was cleaned and mapped in ArcGIS to identify changes in paddock area …
Sustainable Intensification Of Livestock Systems Using Forage Legumes, José C. B. Dubeux Jr., Lynn E. Sollenberger
Sustainable Intensification Of Livestock Systems Using Forage Legumes, José C. B. Dubeux Jr., Lynn E. Sollenberger
IGC Proceedings (1977-2023)
Global human population is increasing and expected to reach 9.7 billion people by 2050. Sustainable intensification (SI) of agricultural systems is key to increase food production while minimizing impact on global natural resources. Forage legumes provide a myriad of ecosystem services (ES) and represent an important tool for promoting SI in livestock systems. Forage legumes associate with soil microorganisms to reduce atmospheric N2. This N input represents a valuable contribution to increase net primary productivity with reduced C footprint. In addition, forage nutritive value generally increases, resulting in greater animal performance. When forage legumes are integrated into livestock …
The Optimum Grazing Time Based On Milk Fatty Acids And Yield For Holstein Lactating Cows Through Eco-Pastoral System In Alpine Grassland, M. Kim, J. Y. Kim, M. H. Jo, C. H. Kim, K. Sung
The Optimum Grazing Time Based On Milk Fatty Acids And Yield For Holstein Lactating Cows Through Eco-Pastoral System In Alpine Grassland, M. Kim, J. Y. Kim, M. H. Jo, C. H. Kim, K. Sung
IGC Proceedings (1977-2023)
This study aimed to detect the optimum grazing time based on milk fatty acids and yield for the Holstein cow (Bos taurus) through eco-pastoral system in Korean alpine grassland. The treatment of grazing time was 3 levels: Non-grazing, Half-day grazing, Full-day grazing. First, the difference of milk fatty acids (saturated fatty acid, unsaturated fatty acid, Total ω-3, etc.) and milk yield was checked by grazing time via ANOVA. Second, various measurements of milk fatty acids were reduced to principal components for effective and obvious detecting the variation as a grazing time. Final, the variations of milk fatty acid …
Effects Of Seasonal Rest Grazing And Diet Selection Of Sheep On Pasture Composition In Bromus Inermis Improved Meadow Steppe, H. Zhang, Y. J. Zhang, N. Liu
Effects Of Seasonal Rest Grazing And Diet Selection Of Sheep On Pasture Composition In Bromus Inermis Improved Meadow Steppe, H. Zhang, Y. J. Zhang, N. Liu
IGC Proceedings (1977-2023)
To develop sustainable grazing management systems based on highly-productive dominant species, it is critical to maintain pasture growth and prevent land degradation on meadow steppe. A field study was performed to identify the impact of seasonal rest grazing on diet selection of sheep and pasture composition in Bromus inermis improved meadow steppe from 2015 to 2017 in Hulunbuir, Inner Mongolia, China. Three seasonal rest grazing strategies were conducted: R1 included a spring rest from June 15 to July 15, R2 a summer rest from July 15 to August 15 and R3 an autumn rest from August 15 to September 15. …
The Effect Of Hay Supplementation On Performance Of Grazing Alpaca In The Peruvian Andes, M. Enciso, C. Gómez, C. Osorio
The Effect Of Hay Supplementation On Performance Of Grazing Alpaca In The Peruvian Andes, M. Enciso, C. Gómez, C. Osorio
IGC Proceedings (1977-2023)
Productivity of alpaca grazing rangelands in the Andes is often limited by the low availability and quality of those pastures during the dry season of the year. The use as supplements of forages cultivated during the rainy season in appropriate areas in the Andes may be a strategy to improve performance of alpacas. Therefore, the supplementation of oat-vetch pellets or oat hay was evaluated and compared with a control group without supplementation. Sixty three female alpacas (15 months of age, 34 ± 1.0 kg BW), divided in three groups, grazing range pastures (6.1% crude protein and 61.3% NDF) during dry …
Ppld Is A De-N-Acetylase Of The Cell Wall Linkage Unit Of Streptococcal Rhamnopolysaccharides, Jeffrey S. Rush, Prakash Parajuli, Alessandro Ruda, Jian Li, Amol Arunrao Pohane, Svetlana Zamakhaeva, Mohammad M. Rahman, Jennifer C. Chang, Artemis Gogos, Cameron W. Kenner, Gérard Lambeau, Michael J. Federle, Konstantin V. Korotkov, Göran Widmalm, Natalia Korotkova
Ppld Is A De-N-Acetylase Of The Cell Wall Linkage Unit Of Streptococcal Rhamnopolysaccharides, Jeffrey S. Rush, Prakash Parajuli, Alessandro Ruda, Jian Li, Amol Arunrao Pohane, Svetlana Zamakhaeva, Mohammad M. Rahman, Jennifer C. Chang, Artemis Gogos, Cameron W. Kenner, Gérard Lambeau, Michael J. Federle, Konstantin V. Korotkov, Göran Widmalm, Natalia Korotkova
Molecular and Cellular Biochemistry Faculty Publications
The cell wall of the human bacterial pathogen Group A Streptococcus (GAS) consists of peptidoglycan decorated with the Lancefield group A carbohydrate (GAC). GAC is a promising target for the development of GAS vaccines. In this study, employing chemical, compositional, and NMR methods, we show that GAC is attached to peptidoglycan via glucosamine 1-phosphate. This structural feature makes the GAC-peptidoglycan linkage highly sensitive to cleavage by nitrous acid and resistant to mild acid conditions. Using this characteristic of the GAS cell wall, we identify PplD as a protein required for deacetylation of linkage N-acetylglucosamine (GlcNAc). X-ray structural analysis indicates …
Forage News [2022-02], Department Of Plant And Soil Sciences, University Of Kentucky
Forage News [2022-02], Department Of Plant And Soil Sciences, University Of Kentucky
Forage News
No abstract provided.
Prostacyclin Promotes Degenerative Pathology In A Model Of Alzheimer’S Disease, Tasha R. Womack, Craig T. Vollert, Odochi Ohia-Nwoko, Monika Schmitt, Saghi Montazari, Tina L. Beckett, David Mayerich, Michael Paul Murphy, Jason L. Eriksen
Prostacyclin Promotes Degenerative Pathology In A Model Of Alzheimer’S Disease, Tasha R. Womack, Craig T. Vollert, Odochi Ohia-Nwoko, Monika Schmitt, Saghi Montazari, Tina L. Beckett, David Mayerich, Michael Paul Murphy, Jason L. Eriksen
Sanders-Brown Center on Aging Faculty Publications
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is the most common form of dementia in aged populations. A substantial amount of data demonstrates that chronic neuroinflammation can accelerate neurodegenerative pathologies. In AD, chronic neuroinflammation results in the upregulation of cyclooxygenase and increased production of prostaglandin H2, a precursor for many vasoactive prostanoids. While it is well-established that many prostaglandins can modulate the progression of neurodegenerative disorders, the role of prostacyclin (PGI2) in the brain is poorly understood. We have conducted studies to assess the effect of elevated prostacyclin biosynthesis in a mouse model of AD. Upregulated prostacyclin expression …
Kentucky Annual Economic Report 2022, Michael W. Clark, James P. Ziliak, Simon Sheather
Kentucky Annual Economic Report 2022, Michael W. Clark, James P. Ziliak, Simon Sheather
Kentucky Annual Economic Report
This report is one of the important ways that the Center for Business and Economic Research fulfills its mission to examine various aspects of Kentucky’s economy as directed by the Kentucky Revised Statutes (KRS 164.738). The analysis and data presented here cover a variety of topics that range from a discussion of Kentucky’s current economic climate to a broad presentation of factors affecting the economy.
The report covers numerous dimensions of Kentucky’s economy including the effects of COVID-19. As the pandemic approaches its third year, COVID-19 continues to dominate the economic narrative. Many aspects of the economy have improved substantially …
Regulatory T Cells Control Effector T Cell Inflammation In Human Prediabetes, Rui Liu, Gabriella H. Pugh, Erin Tevonian, Katherine Thompson, Douglas A. Lauffenburger, Philip A. Kern, Barbara S. Nikolajczyk
Regulatory T Cells Control Effector T Cell Inflammation In Human Prediabetes, Rui Liu, Gabriella H. Pugh, Erin Tevonian, Katherine Thompson, Douglas A. Lauffenburger, Philip A. Kern, Barbara S. Nikolajczyk
Clinical and Translational Science Faculty Publications
A disparate array of plasma/serum markers provides evidence for chronic inflammation in human prediabetes, a condition that is most closely replicated by standard mouse models of obesity and metaflammation. These remain largely nonactionable and contrast with our rich understanding of inflammation in human type 2 diabetes. New data show that inflammatory profiles produced by CD4+ T cells define human prediabetes as a unique inflammatory state. Regulatory T cells (Treg) control mitochondrial function and cytokine production by CD4+ effector T cells (Teff) in prediabetes and type 2 diabetes by supporting T helper (Th)17 or Th1 cytokine production, respectively. These data suggest …
Perceptions On Governance For Effective Adaptation To Climate Change Within Community-Based Wildlife Conservancies In Kenya, S. Kibet, Oliver Vivian Wasonga
Perceptions On Governance For Effective Adaptation To Climate Change Within Community-Based Wildlife Conservancies In Kenya, S. Kibet, Oliver Vivian Wasonga
IGC Proceedings (1977-2023)
Community-based wildlife conservancies (CBC) represent a broad spectrum of new management arrangements and benefit sharing partnerships in natural resource management by none state agents, but who, by virtue of their collective location and activities, are critically placed to shape the present and future status of these resources. This approach of wildlife management is increasingly gaining popularity as an option for achieving sustainable co-existence and complementarity between wildlife conservation and livestock production in the drylands of Kenya. Despite difference in ownership and governance structure in place, all conservancies have instituted new rules of control and access. This study sought to understand …
The Cleaned Approach For Flagging And Addressing Environmental Issues, A. Notenbaert, B. Paul, R. Van Der Hoek, J. Mukiri
The Cleaned Approach For Flagging And Addressing Environmental Issues, A. Notenbaert, B. Paul, R. Van Der Hoek, J. Mukiri
IGC Proceedings (1977-2023)
While livestock presents an important livelihood strategy for many smallholders, it is also held responsible for important environmental impacts. In this paper, we used an online survey to identify the perceptions of global livestock experts on environmental impacts of livestock and how these might be tackled. We then explored how the CLEANED environmental ex-ante assessment tool (Comprehensive Livestock Environmental Assessment for improved Nutrition, a secured Environment and sustainable Development = CLEANED) responds to this and how it can be used to influence decision making towards more environmentally-friendly livestock production.
According to the survey, there was general agreement between researchers, development …
Survey Of The Farm Management, Focusing On The Regional Difference And Cattle Farming In Burkina Faso, H. Kumagai, T. Kawashima, A. Sienou, F. Nagumo
Survey Of The Farm Management, Focusing On The Regional Difference And Cattle Farming In Burkina Faso, H. Kumagai, T. Kawashima, A. Sienou, F. Nagumo
IGC Proceedings (1977-2023)
In Burkina Faso the history using of cattle as draft power for cultivation is not long. This study was conducted to investigate the farm management, focusing on the regional difference and the presence of cattle farming in the country. Interview was carried out on 30 farms from B Province in the Centre-West Region consisting of 8 non-cattle owners (BNs) and 22 cattle owners (BCs), and on 9 farms of cattle owners from H Province in the Haut-Bassins Region (HCs) in November 2013. The average household sizes of BNs, BCs and HCs were 16.5, 27.2 and 31.3, respectively. The ratios of …