Digital Commons Network^™

Cass Sunstein's "New Deal" For Free Speech: Is It An "Un-American" Theory Of Speech?, Richard J. Vangelisti

Kentucky Law Journal

No abstract provided.

Truth Verifiers: From The Hot Iron To The Lie Detector, Richard H. Underwood

Kentucky Law Journal

No abstract provided.

An Examination Of The Training And Reliability Of The Narcotics Detection Dog, Robert C. Bird

Kentucky Law Journal

No abstract provided.

Vegetative Filter Strip Design For Grassed Areas Treated With Animal Manures, Dwayne R. Edwards, Tommy C. Daniel, Philip A. Moore Jr.

Biosystems and Agricultural Engineering Faculty Publications

Vegetative filter strips (VFS) are a low-cost management option that have been demonstrated to be effective in reducing runoff transport of fertilizer constituents applied to grassed areas (pasture or meadow). Runoff quality studies involving fertilizers applied to grassed areas suggest that VFS can be designed by assuming that (1) only infiltration is responsible for pollutant removal, (2) the first post-application runoff event is most important from a water quality perspective (enabling a design event approach), and (3) no pollutant build-up that degrades VFS performance will occur. The purpose of this study was to develop a VFS design algorithm for grassed …

Simulation Of Runoff Transport Of Animal Manure Constituents, Yang Wang, Dwayne R. Edwards, Tommy C. Daniel, H. Don Scott

Biosystems and Agricultural Engineering Faculty Publications

Runoff losses of land-applied animal manure constituents can adversely affect the quality of downstream waters. Reliable mathematical simulation models can help estimate runoff losses of animal manure constituents and identify management measures to reduce these losses. The objective of this study was to develop and calibrate an event-based simulation model to describe the runoff transport of solids (soil and manure particles) and nutrients (nitrogen and phosphorus) from areas treated with animal manure. The resulting model, consisting of linked hydrology, soil/manure transport, and nutrient transport components, is process-oriented and uses measurable parameters to the greatest degree possible. The three components of …

Quality Of Runoff From Four Northwest Arkansas Pasture Fields Treated With Organic And Inorganic Fertilizer, Dwayne R. Edwards, Tommy C. Daniel, John F. Murdoch, Philip A. Moore Jr.

Biosystems and Agricultural Engineering Faculty Publications

Long-term land application of animal manures, even at agronomic rates, can promote accumulation of soil phosphorus (P) which can, in turn, contribute to increased P loadings to downstream waters. The objective of this study was to assess the soil and runoff effects of replacing animal manure as a soil amendment with inorganic fertilizer (ammonium nitrate, NH₄NO₃) on fields that had been treated previously with animal manures. Runoff from two pairs of small fields (0.57 to 1.46 ha) was sampled from September 1991 to April 1994. All fields had been treated previously with animal manures; after runoff …

Poultry Litter-Treated Length Effects On Quality Of Runoff From Fescue Plots, Dwayne R. Edwards, Philip A. Moore Jr., Tommy C. Daniel, Puneet Srivastava

Biosystems and Agricultural Engineering Faculty Publications

Using experimental data and/or mathematical simulation models to identify practices that reduce pollution from manure-treated areas is sometimes perceived as limited by the unknown validity of extrapolating plot-scale data to larger areas and by uncertainties in modeling transport of various pollutants. The objectives of this study were to assess the effect of length of manure treatment on runoff concentrations of poultry litter constituents and to define the modes of transport (particulate versus soluble) for nitrogen (N), phosphorus (P), carbon (C), and solids. Poultry litter was applied to three 1.5- x 18.3-m fescue (Festuca arundinacea Schreb.) plots with runoff collection …

Application Of Simplified Phosphorus Transport Models To Pasture Fields In Northwest Arkansas, Dwayne R. Edwards, C. T. Haan, Andrew N. Sharpley, John F. Murdoch, Tommy C. Daniel, Philip A. Moore Jr.

Biosystems and Agricultural Engineering Faculty Publications

Runoff transport of phosphorus (P) is often predicted from simple equations with parameters determined from data applicable primarily to row-cropped and fallow cover conditions. The applicability, accuracy, and precision of such P transport prediction equations under pasture situations are less well defined. The objectives of this study were to determine parameters of simplified runoff P transport equations for pasture fields and to assess the accuracy and precision of the equations. Runoff, sediment yield, soluble P transport, and particulate P transport data were collected from four pasture fields in northwestern Arkansas. Runoff event enrichment ratios and extraction coefficients were computed, and …

Kentucky Traffic Accident Facts 1996 Report, Kentucky Transportation Center, Kentucky State Police

Kentucky Transportation Center Research Report

KENTUCKY’S TRAFFIC ACCIDENT FACTS report for 1996 is based on accident reports submitted to the Accident Unit housed in the Kentucky State Police Information Services Branch, Records Section. As required by Kentucky Revised statutes 189.635, “every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.” The stated purpose of this requirement is to utilize date on traffic accidents” for such purposes as will improve the traffic safety program in the Commonwealth.” Data contained in …

2,4-Disulfonyl Phenyl Butyl Nitrone, Its Salt And Their Use As Pharmaceuticals, John M. Carney

Pharmacology and Nutritional Sciences Faculty Patents

2,4-disulfonyl α-phenyl-tert-butyl nitrone and its pharmaceutically acceptable salts are disclosed. These materials are useful as pharmaceutical agents for oral or parenteral, e.g. intravenous administration to patients suffering from acute central nervous system oxidation as occurs in a stroke or from gradual central nervous system oxidation which can exhibit itself as progressive central nervous system function loss. The materials are also used to ameliorate the side effects of oxidative-damage causing antineoplastic disease treatments.

Phenyl Butyl Nitrone Compositions And Methods For Treatment Of Oxidative Tissue Damage, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions for treating tissue damage from ischemia contain PBN, or active derivatives thereof, which are active during ischemia in preventing ATP depletion of the cells which predisposes them to subsequent injury during reperfusion, and which are active during reperfusion as oxygen radical scavengers, in a suitable pharmaceutical carrier for systemic or local administration, especially to the CNS, spinal column and eyes. Based on animal studies, the dosage for treating damage due to stroke is in the range of 10 to 300 mg/kg. Similar dosages are useful in treating damage resulting from free radical generation during inflammation, either as a product …

Nitrous Oxide Loss From Poultry Manure-Amended Soil After Rain, Mark S. Coyne, A. Villalba, Robert L. Blevins

Plant and Soil Sciences Faculty Publications

Land application of poultry wastes in Kentucky will increase as the broiler industry grows. If poultry manure stimulates N₂O loss from soil it will reduce the fertilizer N value of this waste. In contrast, stimulated N₂O loss in grass filter strips receiving the runoff from manured fields could help reduce contamination of surface water by NO⁻₃. Our objectives were to determine (i) if poultry manure stimulated N₂O loss in soil after rainfall and (ii) if there was an edge-of-field effect on N₂O loss in grass filters intercepting runoff from …

Polyamine-Polyamine And Polyamine-Protein Transport Inhibitor Conjugates And Their Use As Pharmaceuticals And In Research Relating To Polyamine Transport, Shewan M. Aziz, Mark N. Gillespie

Pharmaceutical Sciences Faculty Patents

Novel classes of inhibitors which selectively inhibit the cellular transport of normally transported substances, specifically polyamines are taught which comprise (i) polymers of the transported substance or (ii) protein or polypeptide conjugates of the transported substance. These inhibitors may be used in vitro to assess the effect of the transported substance on cellular functions and in vivo for treating disease conditions involving transport of the particular substance, e.g., a polyamine.

Involvement Of P59FynT In Interleukin-5 Receptor Signaling, Mark W. Appleby, James D. Kerner, Sylvia Chien, Charles R. Maliszewski, Subbarao Bondada, Roger M. Perlmutter

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Previous studies implicate the nonreceptor protein tyrosine kinase (PTK) p59fyn in the propagation of signals from the B cell antigen receptor. To elucidate the functions of this kinase, we examined B cell responsiveness in mice engineered to lack the hematopoietic isoform of p59fyn. Remarkably, antigen receptor signaling was only modestly defective in fyn^Tnull B cells. In contrast, signaling from the interleukin (IL)-5 receptor which ordinarily provides a comitogenic stimulus with antiimmunoglobulin, was completely blocked. Our results document the importance of p59fyn^T in IL-5 responses in B cells, and they support a general model …

Method For Inhibiting Angiogenesis With Aurintricarboxylic Acid, Its Analogues Or Salts, Delwood C. Collins, Antonio Gagliardi, Anjan Bhattacharyya

Obstetrics and Genecology Faculty Patents

Aurintricarboxylic acid has potent anti-angiogenic activity and may be used for new therapeutic approaches for diseases of neovascularization including the treatment of solid tumors, diabetic retinopathy and arthritis, among others.

Immune Response To The Carcinoembryonic Antigen In Patients Treated With An Anti-Idiotype Antibody Vaccine, Kenneth A. Foon, Mala Chakraborty, William J. John, Amanda Sherratt, Heinz Köhler, Malaya Bhattacharya-Chatterjee

Markey Cancer Center Faculty Publications

We have generated an IgG1 murine monoclonal anti-idiotype antibody (Ab2) designated 3H1, which mimics a specific epitope on the carcinoembryonic antigen (CEA). Patients with CEA positive tumors are immunologically "tolerant" to CEA. We used 3H1 as a surrogate for CEA for vaccine therapy of 12 patients with advanced colorectal cancer. Each of the patients received a minimum of four intracutaneous injections of aluminum hydroxide precipitated 3H1 at either 1, 2, or 4 mg dosage per injection. 9 of 12 patients demonstrated anti-anti-idiotypic (Ab3) response to 3H1. All nine patients generated specific anti-CEA antibody demonstrated by reactivity with radiolabeled purified CEA; …

Non-Destructive Method For Radiolabelling Biomolecules By Halogenation, Anwar A. Hussain, Lewis W. Dittert

Pharmaceutical Sciences Faculty Patents

A kit and method of non-destructively radiolabelling a biomolecule substrate by halogenation, including the steps of: a) reacting a secondary amine with a chlorinating agent to produce an N-chloro secondary amine, (b) reacting the N-chloro secondary amine with a salt of a radiolabelled halogen to produce a radiolabelled halogenating agent, (c) reacting a solution of the biomolecule substrate with the radiolabelled halogenating agent, and (d) recovering a radiohalogenated biomolecule from the reaction of step (c). The kit and method allow for more complete iodination with a lessening of side reactions such as decomposition of the biomolecule substrate to be labelled.

College Of Law Commencement Program, 1995, University Of Kentucky

Graduation Programs

No abstract provided.

Fecal Bacteria In Agricultural Waters Of The Bluegrass Region Of Kentucky, J. M. Howell, Mark S. Coyne, P. L. Cornelius

Plant and Soil Sciences Faculty Publications

Agricultural runoff influenced by nonpoint pollution frequently exceeds the USEPA standards for bacterial contamination of primary contact water (200 fecal coliforms/100 mL). Few studies have evaluated the effect of cattle (Bos taurus) grazing on fecal contamination of ground water in the karst topography of central Kentucky. Our objectives were to: (i) observe the extent and pattern of fecal bacteria in agricultural waters from two central Kentucky watersheds; (ii) determine if monthly sampling accurately assessed the extent and variability of fecal contamination; and (iii) assess the fecal coliform/fecal streptococci ratio (FC/FS) as an indicator of fecal bacteria source. Springs, …

Working The Borderlands, Becoming Mestiza: An Interview With Gloria Anzaldúa, Kakie Urch, Michael L. Dorn, J. Abraham

disClosure: A Journal of Social Theory

No abstract provided.

Artwork: "Garden Series, Iii", Audrey Rooney

disClosure: A Journal of Social Theory

No abstract provided.

I Wanna See Some History: The Border, Identity, Writing, Alan Wright

disClosure: A Journal of Social Theory

No abstract provided.

Pbn, Dmpo, And Pobn Compositions And Method Of Use Thereof For Inhibition Of Age-Associated Oxidation, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing as the active ingredient a spin-trapping reagent, preferably α-phenyl butyl nitrone (PBN) or spin-trapping derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient are disclosed for treating or preventin symptoms associated with aging or other conditions associated with oxidative tissue damage. Other spin-trapping agents can also be used, such as 5,5-dimethyl pyrroline N-oxide (DMPO) or α-(4-pyridyl 1-oxide)-N-tert-butylnitrone (POBN), and other spin-trapping derivatives thereof. These compositions and methods are useful in the treatment of age-related disorders, pre-surgical and/or pre-anesthetic preparation or administration of chemotherapeutic agents, and in the treatment of disorders or trauma of the brain, …

The Use Of Audited Self-Regulation As A Regulatory Technique, Douglas C. Michael

Law Faculty Scholarly Articles

At first blush, "self-regulation" seems to be self-contradicting. If government regulation of an industry or problem is considered necessary, how can that responsibility then be returned to those from whom it was taken? Notwithstanding this apparent contradiction, audited self-regulation is used successfully by federal regulatory agencies. It is apparently adopted, however, on an ad hoc basis: in one industry or application but not in another that possesses similar characteristics. This article reviews these previously uncollected efforts at audited self-regulation to evaluate the general usefulness of this regulatory technique across industries and applications. These insights would be relevant not only to …

Condition Scoring For Your Horse, Craig H. Wood

Agriculture and Natural Resources Publications

In a world where millions of people are taking steps to improve their own physical condition in order to live healthier lives, it only stands to reason that this same concept would be applied to other aspects of their lives and businesses. In Kentucky where horses are a multi-billion dollar industry, the health and welfare (condition) of the horses are of utmost importance to their owners. The ability to accurately assess a horse’s body condition, which is vital to its welfare, weighs heavily on the industry.

Floyd Collins And The Sand Cave Tragedy: A Possible Source For Faulkner's As I Lay Dying, Lucas Carpenter

The Kentucky Review

No abstract provided.

Ceremonies Of Separation In Australian Literature, T. G. Bishop

The Kentucky Review

No abstract provided.

Current Issues In Environmental Law, Office Of Continuing Legal Education At The University Of Kentucky College Of Law, W. Henry Graddy Iv, Jack C. Bender, Thomas W. Fitzgerald, Carl W. Breeding, Marcus P. Mcgraw, Phillip J. Shepherd, David J. Smart, Dennis J. Conniff, Lloyd R. Cress Jr., E. Douglas Stephan, James L. Dickinson, Todd E. Leatherman, Elizabeth U. Natter, W. Patrick Stallard, Rick L. Thomas, Bradley E. Dillon, Vanessa M. Berge, Ronald R. Van Stockum Jr.

Continuing Legal Education Materials

Materials from the Current Issues in Environmental Law seminar held by UK/CLE in April 1995.

How To Make Your Alfalfa More Profitable, Clive Holland

Kentucky Alfalfa and Stored Forage Conference

As a perennial plant, alfalfa can be expected to continue to live and produce for an indefinite period of time. Why then do stands need to be replanted every few years? Is modern seed available today, weakened and unable to live up to the perennial label? What about yield? How does your stand measure up? Are you barely making the state average, or struggling to even meet this modest yield level?

The first harvest each spring can produce over 40% of the yield in a single growing season. Why is a stand slower growing in the spring than you would …

Role Of Alfalfa In Animal Diets, Jennifer L. Garrett

Kentucky Alfalfa and Stored Forage Conference

Alfalfa forage use has increased in all classes of livestock - dairy, beef, horses, sheep, and swine - during the last 40 years. The highest utilization of alfalfa by livestock is found in dairy cattle diets. Additionally, the use of alfalfa as a grazing crop has also undergone a considerable increase with the use of new grazing management techniques and the development of new grazing varieties.

Alfalfa's strength as a forage crop is its high nutritional value. Alfalfa is higher in protein, minerals, and net energy than grasses and small grains. High quality alfalfa also helps to promote intake, especially …